PROFILE

HIRAMATSU Keiichi, M.D., Ph.D.


Emeritus Professor, Microbiology
Director, Center of Excellence for Infection Control Science

Short Biography

1975
M.D. The University of Tokyo Faculty of Medicine
1975-1978
Practiced internal medicine
1978-1983
Research student in Immunology at Tokyo University and Massachusetts Institute of Technology (MIT)
1984-1988
Assistant Professor in Retrovirology at Tokyo University and Tokyo Medical and Dental University
1988
Associate Professor, Department of Microbiology, Juntendo University Faculty of Medicine
1992-2016
Professor, Department of Microbiology, Juntendo University Faculty of Medicine
2012-Present
Director of Infection Control Science Research Center at Juntendo University
 

Main Research Topics and Interests

  • Discovery of staphylococcal cassette chromosome mec (SCCmec) as the genetic determinant of MRSA (1995), Discovery of vancomycin-intermediate Staphylococcus (S.) aureus (VISA) and heterogeneously intermediate-VISA (hVISA) (1997), The first whole genome sequence determination of S. aureus (N315 and Mu50)(2001) (ref. 6), then of CA-MRSA strain MW2 (2002), Proposal of the novel mechanism ‘peptidoglycan clogging’ for the vancomycin resistance of VISA (2006)
  • Discovery of the origin of mecA gene in S. flurettii (2010), Discovery of Reverse Antibiotic (2012)
  • Antibiotics, Antibiotic resistance, Microbiology of MRSA, Micorbial Genomics, Infection Control
  • Reverse Antibiotics, ß-lactam Resistance, Vancmycin resistance, Molecular Epidemiology of Staphylococcus aureus. Anti-MRSA chemotoerapy

Publications (in English)

  • Original Articles (222)
  • Review Articles (20)
  • Book (24)
  • Total Impact Factor (Top 50) (355.589)
  • Citation Index (20,476)

Recent Main Publications

  • Hiramatsu K, Ito T, Tsubakishita S, Sasaki T, Takeuchi F, Morimoto Y, Katayama Y, Matsuo M, Kuwahara-Arai K, Hishinuma T, Baba T: Genomic Basis for Methicillin Resistance in Staphylococcus aureus. Infect Chemother, 2013 Jun; 45 (2): 117-36.
  • Hiramatsu K, Katayama Y, Matsuo M, Sasaki T, Morimoto Y, Sekiguchi A, Baba T: Multi-Drug-Resistant Staphylococcus aureus and Future Chemotherapy. J Infect Chemother, 2014 Oct; 20 (10): 593-601.
  • Hiramatsu K, Katayama Y, Matsuo M, Aiba Y, Saito M, Hishinuma T, Iwamoto A: Vancomycin-intermediate resistance in Staphylococcus aureus. J Glob Antimicrob Resist; 2014 Dec; 2 (4) : 213-224.
  • More

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