RESEARCH

Keywords

• Biology of the skin, Keratin & keratinization, Enzyme/human keratinocyte (lysozyme, TGase, S-S cross linking etc.)
• Autoimmune and congenital bullous diseases & Hereditary skin diseases: (PV, BP, DHD, EBA, REBD, BC1E etc.)
• Atopic dermatitis (AD), Barrier & Immunological dysfunction of AD
• Hair biology and hair disorders, AA, Hair growth
• Medical mycology (keratinolytic protease & their inhibitor : CAPP=SAP, pepstatin)
• Others: Wound healing, Skin tumors

Main Research Topics and Interests

• The mechanism of epidermal differentiation (keratin, keratinization & dyskeratotic diseases)
• The role of proteinases & their inhibitors in skin and skin diseases
• Molecular and cellular biological analysis of hair growth and development

Publications (in English)

• Original Articles: 653
• Review Articles: 33
• Books including chapter: 64
• h-index: 68 (Scopus)
• Sum of Times Cited: 19,033

Recent Main Publications

• Kamata Y, Tominaga M, Umehara Y, Honda K, Kamo A, Moniaga CS, Komiya E, Toyama S, Suga Y, Ogawa H, Takamori K. Calcium-inducible MAPK/AP-1 signaling drives semaphorin 3A expression in normal human epidermal keratinocytes. J Invest Dermatol, 140(7): 1346-1354, 2020 <IF: 7.143>
• Niyonsaba F, Song P, Yue HN, Sutthammikorn N, Umehara Y, Okumura K, Ogawa H. Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 activates mas cells via Mas-related G protein-coupled receptor X2. Allergy, 75(1): 203-207, 2019 <IF: 8.706>
• Nishioka I, Takai T, Maruyama N, Kamijo S, Suchiva P, Suzuki M, Kunimine S, Ochi H, Shimura S, Sudo K, Ogawa H, Okumura K, Ikeda S. Airway inflammation after epicutaneous sensitization of mice requires protease activity of low-dose allergen inhalation. J Allergy Clin Immunol, 141(6): 2271-2273, 2018 <IF: 13.258>