PROFILE

OKUMURA Ko, M.D., Ph.D.


Department of Biofunctional Microbiota

Short Biography

1969
M.D. Chiba University School of Medicine
1973
Ph.D. (Pathology) Chiba University Graduate School of Medicine
1973
Research Associate, NIH
1974
Research Fellow, Department of Genetics, Stanford University
1977
Assistant Professor, Department of Immunology, The University of Tokyo
1979
Associate Professor, Department of Immunology, The University of Tokyo
1983
Professor, Department of Immunology, Juntendo University Faculty of Medicine
2000
Dean, Juntendo University Faculty of Medicine
2008
Director, Atopy Research Center, Juntendo University Graduate School of Medicine
 

Keywords

  • Immunology
  • Allergy
  • Transplantation
  • Cancer
  • Microbiota
  • Probiotics

Main Research Topics and Interests

  • Biological function of Microbiota and Probiotics
  • Immunological mechanisms of Allergy and Atopy
  • Immune responses against cancer
  • Immunological tolerance induction in transplantation

Publications in the last 5 years (English)

  • Original Articles (50)
  • Total Impact Factor (259.37)
  • Total Citation Index (138)

Recent Main Publications

  • Kojima, Y., Nishina, T., Nakano, H., Okumura, K. and Takeda, K.: Inhibition of Importin β1 Augments the Anticancer Effect of Agonistic Anti-Death Receptor 5 Antibody in TNF-Related Apoptosis-Inducing Ligand-Resistant Tumor Cells. Mol. Cancer Ther. 19 (5): 1123-1133, 2020. DOI: 10.1158/1535-7163.MCT-19-0597
  • Takeda, K., Kitaura, K., Suzuki, R., Owada, Y., Muto, S., Okabe, N., Hasegawa, T., Osugi, J., Hoshino, M., Tsunoda, T., Okumura, K., and Suzuki, H.: Quantitative T cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination. Cancer Immunol. Immunother. 67 (6): 946-964, 2018. DOI 10.1007/s00262-018-2152-x.
  • Takeda, K., Nakayama, M., Hayakawa, Y., Kojima, Y., Ikeda, H., Naoko Imai, N., Ogasawara, K., Okumura, K., Thomas, D. M. and Smyth, M. J.: IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting. Nature Commun. 8: 14607, 2017. DOI: 10.1038/ncomms14607.
  • Makino, S., Sato, A., Goto, A., Nakamura, M., Ogawa, M., Chiba, Y., Hemmi, J., Kano, H., Takeda, K., Okumura, K. and Asami, Y.: Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. J. Dairy Science. 99 (2): 915-923. 2016. doi.org/10.3168/jds.2015-10376
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