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研究業績詳細

福 典之(フク ノリユキ)

研究テーマ 運動能力・長寿ならびに生活習慣病に関連する遺伝要因の解明
研究業績(論文) 論文(計146件)

【2020年】(12件)
Zempo H, Kim SJ, Fuku N, Nishida Y, Higaki Y, Wan J, Yen K, Miller B, Vicinanza R, Miyamoto-Mikami E, Kumagai H, Naito H, Xiao J, Mehta HH, Lee C, Hara M, Patel YM, Setiawan VW, Moore TM, Hevener AL, Sutoh Y, Shimizu A, Kojima K, Kinoshita K, Arai Y, Hirose N, Maeda S, Tanaka K, Cohen P. A Pro-Diabetogenic mtDNA Polymorphism in the Mitochondrial-Derived Peptide, MOTS-c. Aging. 2020. [in press]

Kumagai H, Miyamoto-Mikami E, Kikuchi N, Kamiya N, Zempo H, Fuku N. A rs936306 C/T Polymorphism in the CYP19A1 Is Associated With Stress Fractures. J Strength Cond Res. 2020. [in press]

Guilherme JPLF, Semenova EA, Zempo H, Martins GL, Lancha Junior AH, Miyamoto-Mikami E, Kumagai H, Tobina T, Shiose K, Kakigi R, Tsuzuki T, Ichinoseki-Sekine N, Kobayashi H, Naito H, Borisov OV, Kostryukova ES, Kulemin NA, Larin AK, Generozov EV, Fuku N, Ahmetov II. Are Genome-Wide Association Study Identified Single-Nucleotide Polymorphisms Associated With Sprint Athletic Status? A Replication Study With 3 Different Cohorts. Int J Sports Physiol Perform. 2020. [in press]

Miyamoto-Mikami E, Kumagai H, Kikuchi N, Kamiya N, Miyamoto N, and Fuku N. eQTL variants in COL22A1 are associated with muscle injury in athletes. Physiol Genomics. 52(12):588-589. 2020.

Miyamoto-Mikami E and Fuku N. Genetics and genomics in sports. Juntendo Med J. 66(Suppl.1):72-77. 2020.

Yvert T, Miyamoto-Mikami E, Tobina T, Shiose K, Kakigi R, Tsuzuki T, Takaragawa M, Ichinoseki-Sekine N, Pérez M, Kobayashi H, Tanaka H, Naito H, Fuku N. PPARGC1A rs8192678 and NRF1 rs6949152 Polymorphisms Are Associated with Muscle Fiber Composition in Women. Genes. 11(9):E1012.

Massidda M, Myamoto-Mikami E, Kumagai H, Ikeda H, Shimasaki Y, Yoshimura M, Cugia P, Piras F, Scorcu M, Kikuchi N, Calò CM, Fuku N. Association between the ACE I/D polymorphism and muscle injuries in Italian and Japanese elite football players. J Sports Sci. 2:1-7, 2020.

Nishida Y, Hara M, Fuku N, Taguchi N, Horita M, Shimanoe C, Higaki Y, Tanaka K. The interaction between mitochondrial haplogroups (M7a/D) and physical activity on adiponectin in a Japanese population. Mitochondrion. 53:234-242, 2020.

Al-Khelaifi F, Yousri NA, Diboun I, Semenova EA, Kostryukova ES, Kulemin NA, Borisov OV, Andryushchenko LB, Larin AK, Generozov EV, Miyamoto-Mikami E, Murakami H, Zempo H, Miyachi M, Takaragawa M, Kumagai H, Naito H, Fuku N, Abraham D, Hingorani A, Donati F, Botrè F, Georgakopoulos C, Suhre K, Ahmetov II, Albagha O, Elrayess MA. Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism. Front Genet. 11:595, 2020.

Kidokoro T, Fuku N, Yanagiya T, Takeshita T, Takaragawa M, Annear M, Xiaojie T, Waiganjo LB, Bogonko LF, Isika JK, Kigaru MD, Mwangi FM. Physical Activity and Sedentary Behaviour Patterns among Kenyan and Japanese Children: A Comprehensive Cross-Country Comparison. Int J Environ Res Public Health.17(12):E4254, 200.

Semenova EA, Miyamoto-Mikami E, Akimov EB, Al-Khelaifi F, Murakami H, Zempo H, Kostryukova ES, Kulemin NA, Larin AK, Borisov OV, Miyachi M, Popov DV, Boulygina EA, Takaragawa M, Kumagai H, Naito H, Pushkarev VP, Dyatlov DA, Lekontsev EV, Pushkareva YE, Andryushchenko LB, Elrayess MA, Generozov EV, Fuku N, Ahmetov II. The association of HFE gene H63D polymorphism with endurance athlete status and aerobic capacity: novel findings and a meta-analysis. Eur J Appl Physiol. 120(3):665-673, 2020.

Kidokoro T, Kohmura Y, Fuku N, Someya Y, Suzuki K. Secular trends in the grip strength and body mass index of sport university students between 1973 and 2016: J-Fit+Study. J Exerc Sci Fit. 18(1):21-30, 2020.

【2019年】(7件)
Miyamoto-Mikami E, Miyamoto N, Kumagai H, Hirata K, Kikuchi N, Zempo H, Kimura N, Kamiya N, Kanehisa H, Naito H, Fuku N. COL5A1 rs12722 polymorphism is not associated with passive muscle stiffness and sports-related muscle injury in Japanese athletes. BMC Med Genet. 20(1):192, 2019.

Noriyuki Fuku, Hiroshi Kumagai, Ildus I. Ahmetov. Genetics of muscle fiber composition. Sports Exer Nutri Genom. 295-313, 2019.

Myosotis Massidda, Naokazu Miyamoto, Samantha Beckley, Naoki Kikuchi, Noriyuki Fuku. Genetics of flexibility. Sports Exer Nutri Genom. 273-293, 2019.

Eri Miyamoto-Mikami, Noriyuki Fuku. Variation of Mitochondrial DNA and elite athletic performance. Sports Exer Nutri Genom. 129-145, 2019.

Ekaterina A. Semenova, Noriyuki Fuku, Ildus I. Ahmetov. Genetic profile of elite endurance athletes. Sports Exer Nutri Genom. 73-104, 2019.

Hirofumi Zempo, Eri Miyamoto-Mikami, Noriyuki Fuku, Haruka Murakami. Heritability estimates of physical performance-related phenotypes. Sports Exer Nutri Genom. 23-39, 2019.

Kumagai H, Miyamoto-Mikami E, Hirata K, Kikuchi N, Kamiya N, Hoshikawa S, Zempo H, Naito H, Miyamoto N, Fuku N. ESR1 rs2234693 Polymorphism Is Associated with Muscle Injury and Muscle Stiffness. Med Sci Sports Exerc. 51(1):19-26, 2019.

【2018年】(5件)
宮本(三上)恵里、福典之.子どもの体格や運動能力の発育発達におよぼす遺伝の影響. 子どもと発育発達.16(3):193-197, 2018.

Yvert TP, Zempo H, Gabdrakhmanova LJ, Kikuchi N, Miyamoto-Mikami E, Murakami H, Naito H, Cieszczyk P, Leznicka K, Kostryukova ES, Alexeev DG, Egorova ES, Maciejewska-Skrendo A, Larin AK, Generozov EV, Kulemin NA, Ospanova EA, Pavlenko AV, Sawczuk M, Zmijewski P, Lulinska-Kuklik E, Govorun VM, Miyachi M, Ahmetov II, Fuku N. AGTR2 and sprint/power performance: a case-control replication study for rs11091046 polymorphism in two ethnicities. Biol Sport. 35(2):105-109, 2018.

Kumagai H, Tobina T, Ichinoseki-Sekine N, Kakigi R, Tsuzuki T, Zempo H, Shiose K, Yoshimura E, Kumahara H, Ayabe M, Higaki Y, Yamada R, Kobayashi H, Kiyonaga A, Naito H, Tanaka H, Fuku N. Role of selected polymorphisms in determining muscle fiber composition in Japanese men and women. J Appl Physiol (1985). 124(5):1377-1384, 2018.

Miyamoto N, Miyamoto-Mikami E, Hirata K, Kimura N, Fuku N. Association analysis of the ACTN3 R577X polymorphism with passive muscle stiffness and muscle strain injury. Scand J Med Sci Sports. 28(3):1209-1214, 2018.

Miyamoto-Mikami E, Zempo H, Fuku N, Kikuchi N, Miyachi M, Murakami H. Heritability estimates of endurance-related phenotypes: A systematic review and meta-analysis. Scand J Med Sci Sports. 28(3):834-845, 2018.

【2017年】(11件)
Zempo H, Miyamoto-Mikami E, Kikuchi N, Fuku N, Miyachi M, Murakami H. Heritability estimates of muscle strength-related phenotypes: A systematic review and meta-analysis. Scand J Med Sci Sports. 27(12):1537-1546, 2017.

Wang G, Durussel J, Shurlock J, Mooses M, Fuku N, Bruinvels G, Pedlar C, Burden R, Murray A, Yee B, Keenan A, McClure JD, Sottas PE, Pitsiladis YP. Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration. BMC Genomics. 18(Suppl 8):817, 2017.

Fuku N, Díaz-Peña R, Arai Y, Abe Y, Zempo H, Naito H, Murakami H, Miyachi M, Spuch C, Serra-Rexach JA, Emanuele E, Hirose N, Lucia A. Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE. BMC Genomics. 18(Suppl 8):803, 2017.

Aibast H, Okutoyi P, Sigei T, Adero W, Chemjor D, Ongaro N, Fuku N, Konstabel K, Clark C, Lieberman DE, Pitsiladis Y. Foot Structure and Function in Habitually Barefoot and Shod Adolescents in Kenya. Curr Sports Med Rep. 16(6):448-458, 2017.

Matsuo K, Sato K, Suemoto K, Miyamoto-Mikami E, Fuku N, Higashida K, Tsuji K, Xu Y, Liu X, Iemitsu M, Hamaoka T, Tabata I. A Mechanism Underlying Preventive Effect of High-Intensity Training on Colon Cancer. Med Sci Sports Exerc. 49(9):1805-1816, 2017.

Willems S, Wright D, Day D, Trajanoska K, Joshi P, Morris J, Matteini A, Garton F, Grarup N, Oskolkov N, Thalamuthu A, Mangino M, Liu J, Demirkan A, Lek M, Xu L, Wang G, Oldmeadow C, Gaulton K, Lotta L, Miyamoto-Mikami E, Rivas M, White T, Loh PR, Aadahl M, Amin N, Attia J, Austin K, Benyamin B, Brage S, Cheng YC, Cieszczyk P, Derave W, Eriksson KF, Eynon N, Linneberg A, Lucia A, Massidda M, Mitchell B, Miyachi M, Murakami H, Padmanabhan S, Pandey A, Papadimitriou I, Rajpal D, Sale C, Schnurr T, Sessa F, Shrine N, Tobin M, Varley I, Wain L, Wray N, Lindgren C, MacArthur D, Waterworth D, McCarthy M, Pedersen O, Khaw K, Kiel D, GEFOS Anytype of Fracture Consortium, Pitsiladis P, Fuku N, Franks P, North K, Duijn C, Mather K, Hansen T, Hansson O, Spector T, Murabito J, Richards B, Rivadeneira F, Langenberg C, Perry J, Wareham N, Scott R. Large-Scale GWAS Identifies Multiple Loci for Hand Grip Strength Providing Biological Insights into Muscular Fitness. Nat Commun. 8:16015, 2017.

Kikuchi N, Zempo H, Fuku N, Murakami H, Sakamaki-Sunaga M, Okamoto T, Nakazato K, Miyachi M. Association between ACTN3 R577X polymorphism and trunk flexibility in 2 different cohorts. Int J Sports Med. 38(5):402-406, 2017.

Murakami H, Fuku N, Kawakami R, Gando Y, Iemitsu M, Sanada K, Miyachi M. DRD2/ANKK1 gene polymorphism rs1800497 is associated with exercise habit in the period from childhood to adolescence in Japanese. 6(2):95-102, 2017.

Miyamoto-Mikami E, Murakami H, Tsuchie H, Takahashi H, Ohiwa N, Miyachi M, Kawahara T, Fuku N. Lack of association between genotype score and sprint/power performance in the Japanese population. J Sci Med Sport. 20(1):98-103, 2017.

Kiluchi N, Fuku N, Matsumoto R, Murakami H, Miyachi M, Nakazato K. The association between MCT1 T1470A polymorphism and power-oriented athlete performance. Int J Sports Med. 38(1):76-80, 2017.

福典之.基礎体力の遺伝率と遺伝子多型. Journal of Training Science for Exercise and Sport.29(2):81-88, 2017.

【2016年】(12件)
Ishioka YL, Gondo Y, Fuku N, Inagaki H, Masui Y, Takayama M, Abe Y, Arai Y, Hirose N. Effects of the APOE ε4 allele and education on cognitive function in Japanese centenarians. Age (Dordr). 38(5-6):495-503, 2016.

Fuku N, Alis R, Yvert T, Zempo H, Naito H, Abe Y, Arai Y, Murakami H, Miyachi M, Pareja-Galeano H, Emanuele E, Hirose N, Lucia A. Muscle-related polymorphisms MSTN rs1805086 and ACTN3 rs1815739 are not associated with exceptional longevity in Japanese centenarians. PLoS One. 11(11):e0166605, 2016.

Santos-Lozano A, Pareja-Galeano H, Fuku N, Hirose N, Emanuele E, Lucia A, Sanchis-Gomar F. Implication of obesity in exceptional longevity. Ann Transl Med. 4(20):416, 2016.
Yvert T, Miyamoto-Mikami E, Murakami H, Miyachi M, Kawahara T, Fuku N. Lack of replication of associations between multiple genetic polymorphisms and endurance athlete status in Japanese population. Physiol Rep. 4(20):13003, 2016.

Fuku N, Díaz-Peña R, Arai Y, Abe Y, Pareja-Galeano H, Sanchis-Gomar F, Santos-Lozano A, Zempo H, Naito H, Murakami H, Miyachi M, Venturini L, Ricevuti G, Nobuyoshi H, Emanuele E, Lucia A. rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts. Maturitas. 92:110-114, 2016.

Kikuchi N, Miyamoto-Mikami E, Murakami H, Nakamura T, Min SK, Mizuno M, Naito H, Miyachi M, Nakazato K, Fuku N. ACTN3 R577X genotype and athletic performance in a large cohort of Japanese athletes. Eur J Sport Sci. 16(6):694-701, 2016.

Miyamoto-Mikami E, Fujita Y, Murakami H, Ito M, Miyachi M, Fuku N. CNTFR genotype and sprint/power performance: Case-control association and functional studies. Int J Sports Med. 37(5):411-417, 2016.

Fuku N, Miyamoto-Mikami E, Kikuchi N, Zempo H, Naito H. Does the Sports Gene Affect Lifestyle-Related Diseases? Juntendo Med. J. 62(Supple 1):22-28, 2016.

Pitsiladis YP, Tanaka M, Eynon N, Bouchard C, North KN, Williams AG, Collins M, Moran CN, Britton SL, Fuku N, Ashley EA, Klissouras V, Lucia A, Ahmetov II, de Geus EJ, Alsayrafi M. The Athlome Project Consortium: A Concerted Effort to Discover Genomic and other ""OMIC"" Markers of Athletic Performance. Physiol Genomics. 48(3):183-190, 2016.

Wang G, Tanaka M, Eynon N, North KN, Williams AG, Collins M, Moran CN, Britton SL, Fuku N, Ashley EA, Klissouras V, Lucia A, Ahmetov II, de Geus EJ, Alsayrafi M, Pitsiladis YP. The Future of Genomic Research in Athletic Performance and Adaptation to Training. Med Sports Sci. 61:55-67, 2016.

Rankinen T, Fuku N, Wolfarth B, Wang G, Sarzynski MA, Alexeev DG, Ahmetov II, Boulay MR, Cieszczyk P, Eynon N, Filipenko ML, Garton FC, Generozov EV, Govorun VM, Houweling PJ, Kawahara T, Kostryukova ES, Kulemin NA, Larin AK, Maciejewska-Karłowska A, Miyachi M, Muniesa CA, Murakami H, Ospanova EA, Padmanabhan S, Pavlenko AV, Pyankova ON, Santiago C, Sawczuk M, Scott RA, Uyba VV, Yvert T, Perusse L, Ghosh S, Rauramaa R, North KN, Lucia A, Pitsiladis Y, Bouchard C. No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes. PLoS One. 29;11(1):e0147330, 2016.

村上晴香, 膳法浩史, 宮本(三上)恵里, 菊池直樹, 福典之. 運動能力・運動行動の遺伝率. 体力科学. 65(3):277-286, 2016.

菊池直樹, 福典之. 遺伝情報を活用したアスリートのトレーニング方法―. 体育の科学. 66(1):44-49, 2016.

【2015年】(7件)
Webborn N, Williams A, McNamee M, Bouchard C, Pitsiladis Y, Ahmetov I, Ashley E, Byrne N, Camporesi S, Collins M, Dijkstra P, Eynon N, Fuku N, Garton FC, Hoppe N, Holm S, Kaye J, Klissouras V, Lucia A, Maase K, Moran C, North KN, Pigozzi F, Wang G. Direct-to-consumer genetic testing for predicting sports performance and talent identification. Br J Sports Med. 49:1486-1491, 2015.

Fuku N, Pareja-Galeano H, Zempo H, Alis R, Arai Y, Lucia A, Hirose N. The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?. Aging Cell. 14:921-923, 2015.

Fuku N, He ZH, Sanchis-Gomar F, Pareja-Galeano H, Tian Y, Arai Y, Abe Y, Murakami H, Miyachi M, Zempo H, Naito H, Yvert T, Verde Z, Venturini L, Fiuza-Luces C, Santos-Lozano A, Rodriguez-Romo G, Ricevuti G, Hirose N, Emanuele E, Garatachea N, Lucia A. Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795, and ACSL1 rs6552828. Front Aging Neurosci. 6:59, 2015

福典之. DNAとパフォーマンスの関係. Sports Science Magazine. 1(1):6-14, 2015.

福典之. The Sports Gene-人類の遺伝的多様性と運動能力-. Sports Science Magazine.1(1):15, 2015.

福典之. 東アフリカ人の持久的運動能力を規定する遺伝要因ならびに環境要因. ランニング研究. 26:92-99, 2015.

福典之. スポーツと遺伝. 予防医療Aggressive. 2(1):48, 2015.

【2014】(6件)
Sanchis-Gomar F, Garatachea N, He ZH, Pareja-Galeano H, Fuku N, Tian Y, Arai Y, Abe Y, Murakami H, Miyachi M, Yvert T, Santiago C, Venturini L, Fiuza-Luces C, Santos-Lozano A, Rodríguez-Romo G, Ricevuti G, Hirose N, Emanuele E, Lucia A. FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs. Age (Dordr). 36:9733, 2014.

Garatachea N, Fuku N, He ZH, Tian Y, Arai Y, Abe Y, Murakami H, Miyachi M, Yvert T, Venturini L, Santiago C, Santos-Lozano A, Rodriguez-Romo G, Ricevuti G, Pareja-Galiano H, Sanchis-Gomar F, Emanuele E, Hirose N, Lucia A. PTK2 rs7460 and rs7843014 polymorphisms and exceptional longevity: a functional replication study. Rejuvenation Res. 17:430-438, 2014.

Garatachea N, Emanuele E, Calero M, Fuku N, Arai Y, Abe Y, Murakami H, Miyachi M, Yvert T, Verde Z, Zea MA, Venturini L, Santiago C, Santos-Lozano A, Rodríguez-Romo G, Ricevuti G, Hirose N, Rábano A, Lucia A. ApoE gene and exceptional longevity: Insights from three independent cohorts. Exp Gerontol. 53:16-23, 2014.

Pinós T, Fuku N, Cámara Y, Arai Y, Abe Y, Rodríguez-Romo G, Garatachea N, Santos-Lozano A, Miro-Casas E, Ruiz-Meana M, Otaegui I, Murakami H, Miyachi M, Garcia-Dorado D, Hinohara K, Andreu AL, Kimura A, Hirose N, Lucia A. The rs1333049 polymorphism on locus 9p21.3 and extreme longevity in Spanish and Japanese cohorts. Age (Dordr). 36:933-943, 2014.

Murakami H, Iemitsu M, Fuku N, Sanada K, Gando Y, Kawakami R, Miyachi M. The Q223R polymorphism in the leptin receptor associates with objectively measured light physical activity in free-living Japanese. Physiol Behav. 129:199-204, 2014.

Mikami E, Fuku N, Murakami H, Tsuchie H, Takahashi H, Ohiwa N, Tanaka H, Pitsiladis YP, Higuchi M, Miyachi M, Kawahara T, Tanaka M. ACTN3 R577X Genotype is Associated with Sprinting in Elite Japanese Athletes. Int J Sports Med. 35:172-177, 2014.

【2013年】(9件)
Mikami E, Fuku N, Kong QP, Takahashi H, Ohiwa N, Murakami H, Miyachi M, Higuchi M, Tanaka M, Pitsiladis YP, Kawahara T: Comprehensive analysis of common and rare mitochondrial DNA variants in elite Japanese athletes: a case-control study. J Hum Genet. 58:780-787, 2013.

Pitsiladis YP, Wang G, Padmanabhan S, Wolfarth B, Fuku N, Lucia A, Ahmetov II, Cieszczyk P, Collins M, Eynon N, Williams A.: Genetic testing in Sports and exercise. The Sport and Exercise Scientist. 38:16-17, 2013.

Wang G, Padmanabhan S, Wolfarth B, Fuku N, Lucia A, Ahmetov II, Cieszczyk P, Collins M, Eynon N, Klissouras V, Williams A, Pitsiladis Y. Genomics of Elite Sporting Performance: What little We Know and Necessary Advances. Adv Genet. 84:123-149, 2013.

Mikami E, Fuku N, Takahashi H, Ohiwa N, Pitsiladis YP, Higuchi M, Kawahara T, Tanaka M. Polymorphisms in the control region of mitochondrial DNA associated with elite Japanese athlete status. Scand J Med Sci Sports. 23:593-599, 2013.

Pitsiladis Y, Wang G, Wolfarth B, Scott R, Fuku N, Mikami E, He Z, Fiuza-Luces C, Eynon N, Lucia A. Genomics of elite sporting performance: what little we know and necessary advances. Br J Sports Med. 47:550-555, 2013.

Wang G, Mikami E, Chiu LL, DE Perini A, Deason M, Fuku N, Miyachi M, Kaneoka K, Murakami H, Tanaka M, Hsieh LL, Hsieh SS, Caporossi D, Pigozzi F, Hilley A, Lee R, Galloway SD, Gulbin J, Rogozkin VA, Ahmetov II, Yang N, North KN, Ploutarhos S, Montgomery HE, Bailey ME, Pitsiladis YP. Association analysis of ACE and ACTN3 in elite Caucasian and East Asian swimmers. Med Sci Sports Exerc. 45:892-900, 2013.

Tanisawa K, Mikami E, Fuku N, Honda Y, Honda S, Ohsawa I, Ito M, Endo S, Ihara K, Ohno K, Kishimoto Y, Ishigami A, Maruyama N, Sawabe M, Iseki H, Okazaki Y, Hasegawa-Ishii S, Takei S, Shimada A, Hosokawa M, Mori M, Higuchi K, Takeda T, Higuchi M, Tanaka M. Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes. BMC Genomics. 14:248, 2013.

Fuku N, Mikami E, Tanaka M. Association of mitochondrial DNA polymorphisms and/or haplogroups with elite Japanese athlete status. J Phys Fitness Sports Med. 2:17-27, 2013.

Zhou H, Mori S, Kou I, Fuku N, Naka Mieno M, Honma N, Arai T, Sawabe M, Tanaka M, Ikegawa S, Ito H. Association of the formiminotransferase N-terminal sub-domain containing gene and thrombospondin, type 1, domain-containing 7A gene with the prevalence of vertebral fracture in 2427 consecutive autopsy cases. J Hum Genet. 58:109-112, 2013.

【2012年】(9件)
Kato T, Nishigaki Y, Noguchi Y, Fuku N, Ito T, Mikami E, Kitamura K, Tanaka M. Extended screening for major mitochondrial DNA point mutations in patients with hereditary hearing loss. J Hum Genet. 57(12):772-775, 2012.

Kato T, Fuku N, Noguchi Y, Murakami H, Miyachi M, Kimura Y, Tanaka M, Kitamura K. Mitochondrial DNA haplogroup associated with hereditary hearing loss in a Japanese population. Acta Oto-Laryngologica. 132(11):1178-1182, 2012.

de Saint Pierre M, Bravi CM, Motti JM, Fuku N, Tanaka M, Llop E, Bonatto SL, Moraga M. An alternative model for the early peopling of southern South America revealed by analyses of three mitochondrial DNA haplogroups. PLoS One. 7:e43486, 2012.

Muyderman H, Sims NR, Tanaka M, Fuku N, Raghupathi R, Thyagarajan D. The mitochondrial T1095C mutation increases gentamicin-mediated apoptosis. Mitochondrion. 12:465-471, 2012.

Fuku N, Murakami H, Iemitsu M, Sanada K, Tanaka M, Miyachi M. Mitochondrial macrohaplogroup associated with muscle power in healthy adults. Int J Sports Med. 33:410-414, 2012.

Deason M, Scott R, Irwin L, Macaulay V, Fuku N, Tanaka M, Irving R, Charlton V, Morrison E, Austin K, Pitsiladis YP. Impotance of mitochondrial haplotypes and maternal lineage in sprint performance among individuals of West African ancestry. Scand J Med Sci Sports. 22:217-223, 2012.

Fuku N, Mori S, Murakami H, Gando Y, Zhou H, Ito H, Tanaka M, Miyachi M. Association of 29C>T Polymorphism in the Transforming Growth Factor-β1 Gene with Lean Body Mass in Community-Dwelling Japanese Population. Geriatr Gerontol Int. 12:292-297, 2012.

福典之, 家光素行. 遺伝的要因を考慮したコンディショニング⑧ロンドンオリンピックのメダリストと遺伝-メダリストのDNAは特別なのか?-. JATI Express.31:16-17, 2012.

福典之, 田中雅嗣. ミトコンドリアゲノムとヒトの寿命. メディカル・サイエンス・ダイジェスト.38(2):7-10, 2012.

【2011年】(3件)
Mikami E, Fuku N, Takahashi H, Ohiwa N, Scott RA, Pitsiladis YP, Higuchi M, Kawahara T, Tanaka M. Mitochondrial haplogroups associated with elite Japanese athlete status. Br J Sports Med. 45(15):1179-1183, 2011.

Yamada Y, Nishida T, Ichihara S, Sawabe M, Fuku N, Nishigaki Y, Aoyagi Y, Tanaka M, Fujiwara Y, Yoshida H, Shinkai S, Satoh K, Kato K, Fujimaki T, Yokoi K, Oguri M, Yoshida T, Watanabe S, Nozawa Y, Hasegawa A, Kojima T, Han BG, Ahn Y, Lee M, Shin DJ, Lee JH, Jang Y. Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations. Atherosclerosis. 215(1):145-152, 2011.

Sawabe M, Tanaka M, Chida K, Arai T, Nishigaki Y, Fuku N, Mieno MN, Kuchiba A, Tanaka N. Mitochondrial haplogroups A and M7a confer a genetic risk for coronary atherosclerosis in the Japanese elderly: an autopsy study of 1,536 patients. J Atheroscler Thromb. 18(2):166-175, 2011.

【2010年】(9件)
Scott RA, Bailey ME, Moran CN, Wilson RH, Fuku N, Tanaka M, Tsiokanos A, Jamurtas AZ, Grammatikaki E, Moschonis G, Manios Y, Pitsiladis YP. FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males. Eur J Hum Genet. 18(12):1339-1343, 2010.

Mori S, Fuku N, Chiba Y, Tokimura F, Hosoi T, Kimbara Y, Tamura Y, Araki A, Tanaka M, Ito H. Cooperative effect of serum 25-hydroxyvitamin D concentration and a polymorphism of transforming growth factor-beta1 gene on the prevalence of vertebral fractures in postmenopausal osteoporosis. J Bone Miner Metab. 28(4):446-450, 2010.

Nishigaki Y, Fuku N, Tanaka M. Mitochondrial haplogroups associated with lifestyle-related diseases and longevity in the Japanese population. Geriatr Gerontol Int. 10(Suppl 1):S221-S235, 2010.

Wu IC, Ohsawa I, Fuku N, Tanaka M. Metabolic analysis of 13C-labeled pyruvate for noninvasive assessment of mitochondrial function. Ann N Y Acad Sci. 1201:111-120, 2010.

Komaki H, Nishigaki Y, Fuku N, Hosoya H, Murayama K, Ohtake A, Goto Y, Wakamoto H, Koga Y, Tanaka M. Pyruvate therapy for Leigh syndrome due to cytochrome c oxidase deficiency. Biochim Biophys Acta, 1800(3), 313-315, 2010.

Kokubo K, Soeda S, Shinbo T, Hirose M, Fuku N, Nishigaki Y, Tanaka M, Kobayashi H. Macrophages that survive hyperoxia exposure have higher superoxide dismutase activities in their mitochondria. Adv Exp Med Biol. 662:63-69, 2010.

福典之, 田中雅嗣. 特集:分子遺伝学-ミトコンドリアゲノム多型と長寿・健康-. 公衆衛生. 74(9):754-760, 2010.

三上恵里, 福典之, 田中雅嗣. 遺伝子多型とサルコペニア. Geriat Med. 48(2):221-225, 2010.

福典之. ミトコンドリアゲノム多型を利用した生活習慣病予防のためのオーダーメイド運動処方の開発. 上原記念生命科学財団研究報告集. 24:27, 2010.

【2009年】(7件)
Yamada Y, Fuku N, Tanaka M, Aoyagi Y, Sawabe M, Metoki N, Yoshida H, Satoh K, Kato K, Watanabe S, Nozawa Y, Hasegawa A, Kojima T. Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study. Atherosclerosis. 207(1):144-149, 2009.

Ueno H, Nishigaki Y, Kong QP, Fuku N, Kojima S, Iwata N, Ozaki N, Tanaka M. Analysis of mitochondrial DNA variants in Japanese patients with schizophrenia. Mitochondrion. 9(6):385-393, 2009.

Fuku N, Nishigaki Y, Tanaka M. Mitochondrial haplogroup N9a confers resistance against metabolic syndrome and type 2 diabetes mellitus in Asian individuals. Asia Pac J Endcrinol. 1(1):65-73, 2009.

Scott RA, Fuku N, Onywera VO, Boit M, Wilson RH, Tanaka M, H Goodwin W, Pitsiladis YP. Mitochondrial haplogroups associated with elite Kenyan athlete status. Med Sci Sports Exerc. 41(1):123-128, 2009.

福典之, 田中雅嗣. 身体活動とゲノム. 日本臨床. 67(2):108-112, 2009.

福典之. 大腸癌予防のための運動・身体活動. 臨床栄養. 115(6):673-681, 2009.

西垣裕, 上野仁美, 細矢博子, 福典之, 田中雅嗣. 蛍光ビーズアレイを用いたミトコンドリアDNAの網羅的迅速解析法. 基礎老化研究. 33:23-26, 2009.

【2008年】(5件)
Bilal E, Rabadan R, Alexe G, Fuku N, Ueno H, Nishigaki Y, Fujita Y, Ito M, Arai Y, Hirose N, Ruckenstein A, Bhanot G, Tanaka M. Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan. PLoS One. 3(6):e2421, 2008.

Kong QP, Salas A, Sun C, Fuku N, Tanaka M, Zhong L, Wang CY, Yao YG, Bandelt HJ. Distilling artificial recombinants from large sets of complete mtDNA genomes. PLoS One. 3(8):e3016-, 2008.

福典之, 田中雅嗣. サクセスフルエイジングに関連するミトコンドリアゲノム多型の探索. 健康医科学. 23:125-132, 2008.

福典之, 田中雅嗣. 高齢者の体力および身体運動トレーニングに対する身体機能改善効果を規定するミトコンドリアゲノム多型の探索. デサントスポーツ科学. 29:175-182, 2008.

西垣裕, 福典之, 田中雅嗣. ミトコンドリアと酸化ストレス・アポトーシス. Medical Science Digest. 34:339-342, 2008.

【2007年】(9件)
Fuku N, Ochiai M, Terada S, Fujimoto E, Nakagama H, Tabata I. Effect of running training on DMH-induced aberrant crypt foci in rat colon. Med Sci Sports Exerc. 39(1):70-74, 2007.

Nishigaki Y, Yamada Y, Fuku N, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Yamaguchi S, Nozawa Y, Tanaka M. Mitochondrial haplogroup N9b is protective against myocardial infarction in Japanese males. Hum Genet. 120(6):827-836, 2007.

Nishigaki Y, Yamada Y, Fuku N, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Yamaguchi S, Nozawa Y, Tanaka M. Mitochondrial haplogroup A is a genetic risk factor for atherothrombotic cerebral infarction in Japanese females. Mitochondrion. 7(1-2):72-79, 2007.

Tanaka M, Fuku N, Nishigaki Y, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Ito M, Nozawa Y, Yamada Y. Women with mitochondrial haplogroup N9a are protected against metabolic syndrome. Diabetes. 56(2):518-521, 2007.

Fuku N, Park KS, Yamada Y, Nishigaki Y, Cho YM, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Nozawa Y, Lee HK, Tanaka M. Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians. Am J Hum Genet. 80(3):407-415, 2007.

Alexe G, Fuku N, Bilal E, Ueno H, Nishigaki Y, Fujita Y, Ito M, Arai Y, Hirose N, Bhanot G, Tanaka M. Enrichment of longevity phenotype in mtDNA haplogroups D4b2b, D4a, and D5 in the Japanese population. Hum Genet. 121(3-4):347-356, 2007.

Tanaka M, Nishigaki Y, Fuku N, Ibi T, Sahashi K, Koga Y. Therapeutic potential of pyruvate therapy for mitochondrial diseases. Mitochondrion. 7(6):399-401, 2007.

福典之, 西垣裕, 田中雅嗣. ミトコンドリアDNA多型及びハプログループと生活習慣病. ファルマシア. 43:982-987, 2007.

福典之. 生活習慣病の発症機序と身体活動・運動-大腸がん-. 体育の科学. 57(12):894-900, 2007.

【2006年】(5件)
Wu J, Oka J, Higuchi M, Tabata I, Toda T, Fujioka M, Fuku N, Teramoto T, Okuhira T, Ueno T, Uchiyama S, Urata K, Yamada K, Ishimi Y. Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: a randomized placebo-controlled trial. Metabolism. 55(4):423-433, 2006.

Wu J, Oka J, Tabata I, Higuchi M, Toda T, Fuku N, Ezaki J, Sugiyama F, Uchiyama S, Yamada K, Ishimi Y. Effects of isoflavone and exercise on BMD and fat mass in postmenopausal Japanese women: a 1-year randomized placebo-controlled trial. J Bone Miner Res. 21(5):780-789, 2006.

西垣裕, 福典之, 田中雅嗣. 老化とミトコンドリア. Clinical Neuroscience. 24(6):647-649, 2006.

西垣裕, 福典之, 田中雅嗣. ミトコンドリア機能異常と老年病. 日本老年医学会雑誌. 43(3):274-282, 2006.

西垣裕, 福典之, 田中雅嗣. 老化に関連するミトコンドリアゲノム多型. 化学と生物. 44(10):674-680, 2006.

【2005年】(4件)
Guo LJ, Oshida Y, Fuku N, Takeyasu T, Fujita Y, Kurata M, Sato Y, Ito M, Tanaka M. Mitochondrial genome polymorphisms associated with type-2 diabetes or obesity. Mitochondrion. 5(1):15-33, 2005.

福典之, 西垣裕, 田中雅嗣. 長寿に関連するミトコンドリアゲノム多型の網羅的解析技術. 細胞工学. 24:854-860, 2005.

福典之, 西垣裕, 田中雅嗣. 哺乳類ミトコンドリアゲノムの遺伝と進化. ヒトミトコンドリアゲノム多型データベース(mtSNP). 蛋白質・核酸・酵素. 50(14):1753-1758, 2005.

田中雅嗣, 福典之, 武安岳史, 藤田泰典, 伊藤雅史. ミトコンドリア病DNA診断のバイオインフォーマティクス-ミトコンドリアDNAデータベース-. 臨床検査. 49(1):33-43, 2005.

【2004年】(6件)
Tanaka M, Takeyasu T, Fuku N, Li-Jun G, Kurata M. Mitochondrial genome singlenucleotide polymorphisms and their phenotypes in the Japanese. Ann N Y Acad Sci. 1011:7-20, 2004.

Tanaka M, Cabrera VM, González AM, Larruga JM, Takeyasu T, Fuku N, Guo LJ, Hirose R, Fujita Y, Kurata M, Shinoda K, Umetsu K, Yamada Y, Oshida Y, Sato Y, Hattori N, Mizuno Y, Arai Y, Hirose N, Ohta S, Ogawa O, Tanaka Y, Kawamori R, Shamoto-Nagai M, Maruyama W, Shimokata H, Suzuki R, Shimodaira H. Mitochondrial genome variation in eastern Asia and the peopling of Japan. Genome Res. 14(10A):1832-1850, 2004.

田中雅嗣, 武安岳史, 福典之, 藤田泰典. ミトコンドリアDNA多型と生活習慣病. Molecular Medicine. 41(3):22-35, 2004.

田中雅嗣, 武安岳史, 福典之, 藤田泰典. 長寿に関連するミトコンドリアゲノム多型. 日本老年医学会雑誌. 41(4):384-386, 2004.

田中雅嗣, 武安岳史, 福典之, 藤田泰典, 伊藤雅史. 多因子遺伝子疾患としての生活習慣病―SNPs研究の最前線―ミトコンドリア遺伝子型と生活習慣病. 内分泌・糖尿病科. 19(4):382-391, 2004.

福典之, 田畑泉, 佐藤祐造. 多因子遺伝子疾患としての生活習慣病―SNPs研究の最前線―:運動療法の効果と遺伝子多型. 内分泌・糖尿病科. 19(4):392-398, 2004.

【2003年】(4件)
福典之, 武安岳史, 田中雅嗣, 押田芳治. ダイエットの科学−体質と遺伝子型−. 体育の科学. 53(3):167-171, 2003.

福典之, 田中雅嗣. 肥満に関連するミトコンドリアゲノム多型. 肥満研究. 9(1):88-89, 2003.

福典之, 田中雅嗣. 肥満に関連するミトコンドリアゲノム一塩基多型の発見. 医学のあゆみ. 205(6):420-421, 2003.

田中雅嗣, 武安岳史, 福典之. 日本人のミトコンドリア遺伝子多型とその表現型−ミトコンドリアゲノム多型データベース−. 実験医学. 21(13):1717-1723, 2003.

【2002年】(3件)
Fuku N, Oshida Y, Takeyasu T, Guo LJ, Kurata M, Yamada Y, Sato Y, Tanaka M. Mitochondrial ATPase subunit 6 and cytochrome B gene polymorphisms in young obese adults. Biochem Biophys Res Commun. 290(4):1199-1205, 2002.

Tanaka M, Borgeld HJ, Zhang J, Muramatsu S, Gong JS, Yoneda M, Maruyama W, Naoi M, Ibi T, Sahashi K, Shamoto M, Fuku N, Kurata M, Yamada Y, Nishizawa K, Akao Y, Ohishi N, Miyabayashi S, Umemoto H, Muramatsu T, Furukawa K, Kikuchi A, Nakano I, Ozawa K, Yagi K. Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria. J Biomed Sci. 9(6):534-541, 2002.

Tanaka M, Fuku N, Takeyasu T, Guo LJ, Hirose R, Kurata M, Borgeld HJ, Yamada Y, Maruyama W, Arai Y, Hirose N, Oshida Y, Sato Y, Hattori N, Mizuno Y, Iwata S, Yagi K. Golden mean to longevity: rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease. J Neurosci Res. 70(3):347-355, 2002.

【2001年】(4件)
Umetsu K, Tanaka M, Yuasa I, Saitou N, Takeyasu I, Fuku N, Naito E, Ago K, Nakayashiki N, Miyoshi A, Kashimura S, Watanabe G, Osawa M. Multiplex amplified product-length polymorphism analysis for rapid detection of human mitochondrial DNA variations. Electrophoresis. 22(16):3533-3538, 2001.

Han Y, Oshida Y, Li L, Koshinaka K, Fuku N, Yamanouchi K, Sato Y. Effect of voluntary wheel-running on insulin sensitivity and responsiveness in high-fat-fed rats. Endocr J. 48(5):551-555, 2001.

李玲, 押田芳治, 韓艶清, 福典之, 北越香織, 佐藤祐造. 一酸化窒素(NO)のインスリン作用発現に果たす役割−euglycemic clamp法を用いた検討−. 糖尿病. 43(4):301-306, 2001.

福典之, 押田芳治, 韓艶清, 越中敬一, 佐藤祐造. 高CO2吸入が糖負荷後の血糖値に及ぼす影響. 総合保健体育科学. 24(1):25-28, 2001.

【2000年】(4件)
Oshida Y, Tachi Y, Morishita Y, Kitakoshi K, Fuku N, Han YQ, Ohsawa I, Sato Y. Nitric oxide decreases insulin resistance induced by high-fructose feeding. Horm Metab Res. 32(9):339-342, 2000.

北越香織, 押田芳治, 韓艶清, 福典之, 佐藤祐造. 食事組成の相違がインスリン作用に及ぼす影響. 総合保健体育科学. 23(1):19-21, 2000.

韓艶清, 押田芳治, 北越香織, 福典之, 佐藤祐造. 高血糖やグルコサミンがインスリン感受性におよぼす影響. 総合保健体育科学. 23(1):22-25, 2000.

加藤公彦, 山本貴子, 福典之, 柴田優子, 長崎大, 田村勝彦, 掛見宏一, 佐藤祐造: 携帯型血中乳酸濃度測定器(ラクテートプロTM)を用いた乳酸閾値(LT)測定の試み-糖尿病運動処方作成における有用性-. 臨床スポーツ医学. 17(8):1007-1011, 2000.

【1999年】(1件)
李玲, 押田芳治, 韓艶清, 北越香織, 福典之, 佐藤祐造. 一酸化窒素(NO)のインスリン作用に及ぼす影響−euglycemic clamp法を用いた検討−. 総合保健体育科学. 22(1):53-56, 1999.

【1998年】(1件)
小林啓三, 猪股俊二, 成澤三雄, 関和彦, 刈谷文彦, 福典之, 朱容仁, 春日規克, 湊久美子. 発育期の運動習慣がそれ以降の時期における運動機能にどのような影響を与えているか?−発育期の運動習慣が身体に与える影響−. 武道・スポーツ科学研究所年報. 3:41-56, 1998.

【1997年】(1件)
春日規克, 成澤三雄, 福典之. 個体差の発生にどのような因子が関与しているか−同腹ラット骨格筋の形態と機能における加齢と個体差−. 小野スポーツ科学. 5:139-149, 1997.

【1996年】(1件)
成澤三雄, 小林啓三, 関和彦, 刈谷文彦, 福典之, 春日規克, 鈴木英樹, 辻本尚弥,山下晋,稲垣洋,小笠原仁美,湊久美子, 森本茂,原 英喜. 個体差の発生にどのような因子が関与しているか−生理的諸項目の因子分析による新たな解釈について−. 小野スポーツ科学. 4:155-172, 1996.

【1995年】(1件)
成澤三雄, 小林啓三, 関和彦, 刈谷文彦, 福典之, 春日規克, 鈴木英樹, 小坂井留美, 辻本尚弥, 稲垣洋, 小笠原仁美, 湊久美子, 山内秀樹, 森本茂, 原英喜, 町田修一. 個体差の発生にどのような因子が関与しているか−成長期における体重と骨格筋について−. 小野スポーツ科学. 3:145-166, 1995.

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