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研究者詳細


区分 教員
学部・大学院 大学院医学研究科
所属 人体の生命機能 神経学
職名 主任教授 
氏名 服部 信孝(ハットリ ノブタカ)
連絡先住所 〒113-8421 東京都文京区本郷2-1-1
電話番号 03-3813-3111
メールアドレス nhattori@juntendo.ac.jp
研究分野 パーキンソン病の発症機序,神経変性疾患の分子生物学,臨床神経学
研究分野を表すキーワード パーキンソン病の発症機序,神経変性疾患の分子生物学,臨床神経学
出身学校、専攻等 順天堂大学医学部 1985年
出身大学院、研究科等 順天堂大学大学院 1994年
取得学位 医学博士 1994年
研究職歴 1985 M.D., Juntendo University Faculty of Medicine
1986-1988 Resident in Neurology, Department of Neurology, Fuji, National Hospital
1988-1989 Assistant Professor of Neurology, Juntendo University
1990-1994 Ph.D. Juntendo University Graduate School of Medicine
1990-1993 Study Molecular Biology as a Special Graduate Student at Department of Biological Chemistry at the Faculty of Medicine, University of Nagoya
1994-1995 Medical Staff, Department of Neurology, Tokyo Metropolitan Ebara Hospital
1995-1998 Assistant Professor, Department of Neurology, Juntendo University
1999-2003 Lecturer, Department of Neurology, Juntendo University
2003-2006 Associate Professor, Department of Neurology, Juntendo University
2006-Present Professor and Chairman, Department of Neurology, Juntendo University Faculty of Medicine
2019-Present Dean, Faculty of Medicine & Graduate School of Medicine, Juntendo University
2020-Present Team Leader, Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science


Prof. Nobutaka Hattori has been interested in the etiology and pathogenesis of Parkinson’s disease (PD) and he found decrease in the amount of complex I in the substantia nigra of Parkinson’s disease patients. Then he and his collaborators identified the disease gene for an autosomal recessive form of young onset familial PD, and named the gene as “parkin”. This is the second form of familial PD in which the disease gene was identified. And they found that the gene product, parkin is direct linked to ubiquitin-proteasome pathway as an ubiquitin ligase. This discovery suggested that protein degradation system is involved in the pathogenesis of not only monogenic PD but also sporadic form.
受賞学術賞 2001 The Encouragement prize for Japan Foundation for Aging and Hearlth
2002 The 39th Baelz Prize
2003 The Award for Japanese Society of Neurology
2012 The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology
2017  The Narabayashi Award from Japanese Society of Neurology

所属学会 Japan Society for the Promotion of Science, Program Officer of Research Center for Science System, 2015-

The Open University of Japan, Visiting Professor, 2016-

MDS member, MDS-AOS Leadership/ officers 2017-2019, Past Chair

American Neurological Association, Corresponding fellow, 2003-

Spanish Association of Neurology, Honorary member, 2017-

Japanese Society of Neurology
The Japanese Society of Mitochondrial Research and Medicine, Director

Movement Disorders Society Japan, Executive Committee
Japanese Society of Neurological Therapeutics, Director

The Japanese Society for Apheresis, Councilor

The Japanese Biochemical Society

The Molecular Biology Society of Japan

The Japanese Society of Neuropathology

Japanese Headache Society

Japan Society for Equilibrium Research

Japan Society for Dementia Research

Japan Parkinson Disease Association (Meeting of PD Patients); Adviser

International Association of Parkinsonism and related disorders (Executive member,2014~)

学位論文 Hattori N, Ikebe S, Tanaka M, Ozawa T, Mizuno Y. Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Adv Neurol. 1993;60:292-6. PubMed PMID: 8380521.
取得資格(認定、専門医等) 医師免許、神経内科専門医、国民健康保険医、内科認定医、難病指定医、肢体不自由診断医
科研費研究者番号 80218510
更新日 2023-09-01

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