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大学院医学研究科各研究分野紹介一覧寄付講座認知症診断・予防・治療学 寄付講座一覧へ

認知症診断・予防・治療学講座
 

業績


 

英文原著論文

 
  1. Hara Y, Motoi Y, Hikishima K, Mizum H, Onoe H, Matsumoto SE, Elahi M, Okano H, Aoki S, Hattori N Involvement of the septo-hippocampal cholinergic pathway in association with septal acetylcholinesterase upregulation in a mouse model of tauopathy. Hara. Curr Alzheimer Res. 2016 Jun 2
  2. Elahi M, Motoi Y, Matsumoto S, Hasan Z, Ishiguro K, Hattori N. Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice. Neurosci. Lett. 610 (2016)207-212.
  3. Elahi M, Hasan Z, Motoi Y, Matsumoto S, Ishiguro K, Hattori N. Region-specific vulnerability to oxidative stress, Neuroinflammation, and Tau hyperphosphorylation in experimental diabetes Mellitis mice. J Alz Dis. 2016 Feb 25;51(4):1209-1224
  4. Matsumoto SE, Motoi Y, Ishiguro K, Tabira T, Kametani F, Hasegawa M, Hattori N. The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties. Hum Mol Genet. 2015 Nov 15;24(22):6403-16
  5. Ogaki K, Li Y, Takanashi M, Ishikawa K, Kobayashi T, Nonaka T, Hasegawa M,Kishi M, Yoshino H, Funayama M, Tsukamoto T, Shioya K, Yokochi M, Imai H, Sasaki R, Kokubo Y, Kuzuhara S, Motoi Y, Tomiyama H, Hattori N. Analyses of the MAPT,PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS.Parkinsonism Relat Disord. 2013 Jan;19(1):15-20.
  6. Nakayama S, Kamagata K, Sano T, Shimada Y, Tanaka Y, Fukui T, Urabe T, Aoki S,Hattori N, Motoi Y. Verbal dysflucency as a consequence of basal ganglia infarction with selective involvement of dorsolateral prefrontal fiber tract. J Neurol. 2013 Sep;260(9):2427
  7. Shimada K, Motoi Y, Ishiguro K, Kambe T, Matsumoto S, Itaya M, Kunichika M, Mori H, Shinohara S, Chiba M, Mizuno Y, Ueno T, Hattori N. Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion Neurobiol Dis. 46 2012 101-108
  8. Kambe T, Motoi Y, Inoue R, Kojima N, Tada N, Kimura T, Sahara N, Yamashita S, Mizoroki T, Takashima A, Shimada K, Ishiguro K, Mizuma H, Onoe H, Mizuno Y, Hattori N. Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice Neurobiol Dis. 42 (2011) 404-414.
  9. Kamakagata K, Motoi Y, Shimogi K, Nakanishi A, Hori M, Mizuno Y, Hattori N, Aoki S. posterior hypoperfusion in Parkinson's disease and Parkinson's disease with dementia measured with arterial spin-labering MR imaging J MRI 33:803-807 (2011)
  10. Kamagata K, Motoi Y, Abe O, Shimoji K, Hori M, Nakanishi A, Sano T, Kuwatsuru R, Aoki S, Hattori N.White matter alterlation of the cingulum in Parkinson's disease with and without dementia: evaluation by diffusion tensor tract-specific analysis. America. AJNR 33:890-895
  11. Ogaki K, Motoi Y, Li Y, Tomiyama H, Shimizu N, Takanashi M, Nakanishi A, Yokoyama K, Hattori N. Visual grasping in FTDP-17 (MAPT): A comparison of N-isopropyl-p-[(123)I]-iodoamphetamine brain perfusion single photon emission computed tomography. Mov Disord 2011, 26(3) 561-563.
  12. Shibata N, Motoi Y, Tomiyama H, Ohnuma T, Kuerban B, Tomson K, Komatsy M, HattoriN, Arai H. Lack of Genetic association of the UCHL1Gene with Alzheimer's disease and Parkinson's disease with dementia. Demen Geriatr Cogn Disord 2012;33;250-254.
  13. Miyajima M, Makajima M, Ogino I, Miyata J, Motoi Y, Arai H. Soluble amyloid precursor protein α in the cerebrospinal fluid as a diagnostic and prognostic biomarker for idiopathic normal pressure hydrocephalus. Euopean J Neurol 2012:1468-1331
  14. Ogaki K, Li Y, Takanashi M, Ishikawa KI, Kobayashi T, Nonaka T, Hasegawa M, Kishi M, Yoshino H, Funayama M, Tsukamoto T, Shioya K, Yokochi M, Imai H, Sasaki R, Kokubo Y, Kuzuhara S, Motoi Y, Tomiyama H, Hattori N. Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS. Parkinsonism Relat Disord. 2012 Jul 18
  15. Hara, H., Mouri, A., Yonemitsu, Y., Nabeshima, T., & Tabira, T. Mucosal immunotherapy in an Alzheimer mouse model by recombinant Sendai virus vector carrying Aβ1-43/IL-10 cDNA Vaccine. 2011, Oct 6;29(43):7474-82
  16. Hara, H., Nanri, Y., Tabata, E., Mitsutake, S., & Tabira, T. Identification of astrocyte-derived immune suppressor factor that induces apoptosis of autoreactive T cells Journal of Neuroimmunology, 2011, 233(1-2), 135-146.
  17. Himeno, E., Ohyagi, Y., Ma, L., Nakamura, N., Miyoshi, K., Sakae, N., Motomura, K., Soejima N., Yamasaki R., Hashimoto T., Tabira T. Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation Annals of neurology, 69(2), 248-256.
 
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