全て開く
2022年
  • T Mimori, T Shukuya, R Ko, Y Okuma, T Koizumi, H Imai, Y Takiguchi, E Miyauchi, H Kagamu, T Sugiyama, K Azuma, Y Namba, M Yamasaki, H Tanaka, Y Takashima, S Soda, O Ishimoto, N Koyama, K Kobayashi, K Takahashi. Clinical Significance of Tumor Markers for Advanced Thymic Carcinoma: A Retrospective Analysis from the NEJ023 Study. Cancers (Basel)., 2022; 14(2): 331.
  • MR Woodford, A Andreou, M Baba, I van de Beek, C Di Malta, I Glykofridis, H Grimes, EP Henske, O Iliopoulos, M Kurihara, R Lazor, WM Linehan, K Matsumoto, SJ Marciniak, Y Namba, A Pause, N Rajan, A Ray, LS Schmidt, W Shi, OK Steinlein, J Thierauf, R Zoncu, A Webb, M Mollapour. Seventh BHD international symposium: recent scientific and clinical advancement. Oncotarget., 2022; 13: 173-181.
  • H Tad, T Mitsudomi, T Misumi, K Sugio, M Tsuboi, I Okamoto, Y Iwamoto, N Sakakura, S Sugawara, S Atagi, T Takahashi, H Hayashi, M Okada, H Inokawa, H Yoshioka, K Takahashi, M Higashiyama, I Yoshino, K Nakagawa; West Japan Oncology Group. Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non-Small-Cell Lung Cancer With EGFR Mutation (IMPACT). J Clin Oncol., 2022; 40(3): 231-241.
  • A Wirawan, K Tajima, F Takahashi, Y Mitsuishi, W Winardi, M Hidayat, D Hayakawa, N Matsumoto, K Izumi, T Asao, R Ko, N Shimada, K Takamochi, K Suzuki, M Abe, O Hino, Y Sekido, K Takahashi. A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma By Suppressing LSD1. Mol Cancer Res., 2022; 20(1): 127-138.
  • H Nakayama, E Oshima, T Hotta, K Hanafusa, K Nakamura, N Yokoyama, H Ogawa, K Takamori, K Iwabuchi. Identification of anti-lipoarabinomannan antibodies against mannan core and their effects on phagocytosis of mycobacteria by human neutrophils. Tuberculosis (Edinb)., 2022; 132: 102165.
  • H Jo, T Yoshida, H Horinouchi, S Yagishita, Y Matsumoto, Y Shinno, Y Okum, Y Goto, N Yamamoto, K Takahashi, N Motoi, Y Ohe. Prognostic significance of cachexia in advanced non-small cell lung cancer patients treated with pembrolizumab. Cancer Immunol Immunother., 2022; 71(2):387-398.
  • N Enomoto, S Homma, N Inase, Y Kondoh, T Saraya, H Takizawa, Y Inoue, H Ishii, Y Taguchi, S Izumi, Y Yamano, Y Tanino, Y Nishioka, M Toyoshima, K Yokomura, S Imokawa, N Koshimizu, T Sano, T Akamatsu, H Mukae, M Kato, N Hamada, H Chiba, S Akagawa, S Muro, H Uruga, H Matsuda, Y Kaida, M Kanai, K Mori, M Masuda, H Hozumi, T Fujisawa, Y Nakamura, N Ogawa, T Suda. Prospective nationwide multicentre cohort study of the clinical significance of autoimmune features in idiopathic interstitial pneumonias. Thorax., 2022; 77(2): 143-153.
  • N Enomoto, S Homma, N Inase, Y Kondoh, T Saraya, H Takizawa, Y Inoue, H Ishii, Y Taguchi, S Izumi, Y Yamano, Y Tanino, Y Nishioka, M Toyoshima, K Yokomura, S Imokawa, N Koshimizu, T Sano, T Akamatsu, H Mukae, M Kato, N Hamada, H Chiba, S Akagawa, S Muro, Uruga H, Matsuda H, Kaida Y, Kanai M, Mori K, Masuda M, Hozumi H, Fujisawa T, Nakamura Y, Ogawa N, Suda T. Prospective nationwide multicentre cohort study of the clinical significance of autoimmune features in idiopathic interstitial pneumonias. Thorax. 2022 Feb;77(2):143-153.
  • K Enomoto, Y Eguchi, T Sato, M Norimoto, M Inoue, A Watanabe, T Sakai, M Yoneyama, Y Aoki, S Orita, M Narita, K Inage, Y Shiga, T Umimura, M Sato, M Suzuki, H Takaoka, N Mizuki, G Kim, T Hozumi, N Hirosawa, T Furuya, S Maki, J Nakamura, S Hagiwara, M Koda, T Akazawa, H Takahashi, K Takahashi, S Ohtori. Usefulness of Simultaneous Magnetic Resonance Neurography and Apparent T2 Mapping for the Diagnosis of Cervical Radiculopathy. Asian Spine J., 2022; 16(1): 47-55.
  • E Miyawaki, H Kenmotsu, Y Shintani, I Sekine, T Shukuya, K Takayama, A Inoue, I Okamoto, K Kiura, K Takahashi, Yamamoto N, Kawaguchi T, Miyaoka E, Yoshino I, Date H. Efficacy of platinum agents for stage III non-small-cell lung cancer following platinum-based chemoradiotherapy: a retrospective study. BMC Cancer., 2022; 22(1): 342.
  • SS Shimamura, T Shukuya, T Asao, D Hayakawa, K Kurokawa, S Xu, K Miura, Y Mitsuishi, K Tajima, R Shibayama, N Shimada, F Takahashi, K Takahashi. Survival past five years with advanced, EGFR-mutated or ALK-rearranged non-small cell lung cancer-is there a "tail plateau" in the survival curve of these patients? BMC Cancer., 2022; 22(1): 323.
  • A Harigai, AI Saito, T Inoue, M Suzuki, Y Namba, Y Suzuki, F Makino, O Nagashima, S Sasaki, K Sasai. The prognostic value of (18)F-FDG PET/CT taken immediately after completion of radiotherapy for lung cancer treated with concurrent chemoradiotherapy: A pilot study. Cancer Radiother., 2022; 26: 711-716
  • S Ueda, J Ito, N Harada, S Harada, H Sasano, Y Sandhu, Y Tanabe, S Abe, S Shiota, Y Kodama, T Nagaoka, F Makino, A Chiba, H Akiba, R Atsuta, A Miyake, K Takahashi. Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen. Biomolecules., 2022; 12(4): 518.
  • S Xu, T Shukuya, J Tamura, S Shimamura, K Kurokawa, K Miura, T Miyawaki, D Hayakawa, T Asao, K Yamamoto, K Takahashi. Heterogeneous Outcomes of Immune Checkpoint Inhibitor Rechallenge in Patients With NSCLC: A Systematic Review and Meta-Analysis. JTO Clin Res Rep., 2022; 3(4): 100309.
  • K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi. Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation. Sci Rep., 2022; 12(1): 5181
  • Y Yan, T Naito, Y Tabe, K Ito, S Nojiri, GA Deshpande, K Seyama, K Takahashi. Increased delta variant SARS-CoV-2 infections in a highly vaccinated medical center in Japan. Vaccine., 2022; 40(23): 3103-3108.
  • NA Nitta, T Sato, M Komura, H Yoshikawa, Y Suzuki, A Mitsui, E Kuwasaki, F Takahashi, Y Kodama, K Seyama, K Takahashi. Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs. Am J Physiol Lung Cell Mol Physiol., 2022; 322(5): L699-L711.
  • K Tsuchihashi, Y Hirata, J Yamasaki, K Suina, K Tanoue, T Yae, K Masuda, E Baba, K Akashi, Y Kitagawa, H Saya, O Nagano. Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer. Biochem Biophys Rep., 2022; 30: 101246.
  • G Igawa, T Ai, T Yamamoto, K Ito, S Nojiri, K Saito, M Wakita, H Fukuda, S Hori, S Misawa, T Miida, K Seyama, K Takahashi, Y Tabe, T Naito. Antibody response and seroprevalence in healthcare workers after the BNT162b2 vaccination in a University Hospital at Tokyo. Sci Rep., 2022; 12(1): 8707.
  • Y Nanjo, T Okuma, Y Kuroda, E Hayakawa, K Shibayama, T Akimoto, R Murashima, K Kanamori, T Tsutsumi, Y Suzuki, Y Namba, F Makino, O Nagashima, S Sasaki, K Takahashi. Multiple Types of Taste Disorders among Patients with COVID-19. Intern Med. , 2022; ;61(14): 2127-2134.
  • M Torasawa, T Yoshida, S Yagishita, Y Shimoda, M Shirasawa, Y Matsumoto, K Masuda, Y Shinno, Y Okuma, Y Goto, H Horinouchi, N Yamamoto, K Takahashi, Y Ohe. Nivolumab versus pembrolizumab in previously-treated advanced non-small cell lung cancer patients: A propensity-matched real-world analysis. Lung Cancer., 2022; 167: 49-57.
  • K Tsuchiya, Y Hosaka, T Takahashi, M Chonan, Y Makita, I Katayama, T Ai, M Idei, Y Horiuchi, K Yamatani, M Wakita, S Misawa, A Okuzawa, T Miida, T Naito, K Takahashi, Y Tabe. Meals and Room Temperature Storage do not Significantly Affect Feasibility of Direct RT-PCR Tests for SARS-CoV-2 Using Saliva. Clin Lab., 2022; 68(6). doi:10.7754/Clin.Lab.2021.210451.
  • T Miyawaki, T Naito, K Doshita, H Kodama, M Mori, N Nishioka, Y Iida, E Miyawaki, N Mamesaya, H Kobayashi, S Omori, R Ko, K Wakuda, A Ono, H Kenmotsu, H Murakami, K Mori, H Harada, M Endo, K Takahashi, T Takahashi. Predicting the efficacy of first-line immunotherapy by combining cancer cachexia and tumor burden in advanced non-small cell lung cancer. Thorac Cancer., 2022; 13(14): 2064-2074.
  • T Yoshida, T Nagaoka, Y Nagata, Y Suzuki, T Tsutsumi, S Kuriyama, J Watanabe, S Togo, F Takahashi, M Matsushita, Y Joki, H Konishi, S Nunomura, K Izuhara, SJ Conway, K Takahashi. Periostin-related progression of different types of experim;ental pulmonary hypertension: A role for M2 macrophage and FGF-2 signalling. Respirology.; 2022; 27(7): 529-538.
  • H Namkoong, K Takahashi, Y Okada, et al. DOCK2 is involved in the host genetics and biology of severe COVID-19. Nature., 2022; 609(7928): 754-760.
  • C Iwamura, K Hirahara, M Kiuchi, S Ikehara, K Azuma, T Shimada, S Kuriyama, S Ohki, E Yamamoto, Y Inaba, Y Shiko, A Aoki, K Kokubo, R Hirasawa, T Hishiya, K Tsuji, T Nagaoka, S Ishikawa, A Kojima, H Mito, R Hase, Y Kasahara, N Kuriyama, T Tsukamoto, S Nakamura, T Urushibara, S Kaneda, S Sakao, M Tobiume, Y Suzuki, M Tsujiwaki, T Kubo, T Hasegawa, H Nakase, O Nishida, K Takahashi, K Baba, Y Iizumi, T Okazaki, MY Kimura, I Yoshino, H Igari, H Nakajima, T Suzuki, H Hanaoka, TA Nakada, Y Ikehara, K Yokote, T Nakayama. Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity. Proc Natl Acad Sci U S A., 2022; 119(33): e2203437
  • SQ Wang, K Takahashi, Y Okada, et al. The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force. Nat Commun., 2022; 13(1): 4830.
  • M Komura, T Sato, H Yoshikawa, N Arano Nitta, Y Suzuki, K Koike, Y Kodama, K Seyama, K Takahashi. Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways. Respir Res., 2022; 23(1): 216.
  • M Takahashi, T Ai, K Sinozuka, Y Baba, G Igawa, S Nojiri, T Yamamoto, M Yuri, S Takei, K Sait, Y Horiuchi, T Kanno, M Tobiume, A Khasawneh, FJ Paran, M Hiki, M Wakita, T Miida, T Suzuki, A Okuzawa, K Takahashi, T Naito, Y Tabe. Activation of SARS-CoV-2 neutralizing antibody is slower than elevation of spike-specific IgG, IgM, and nucleocapsid-specific IgG antibodies. Scientific reports., 2022; 12(1): 14909.
  • B Heissig, Y Salama, R Iakoubov R, Vehreschil JJ, Rios R, Nogueira T, Vehreschild MJGT, Stecher M, Mori H, Lanznaster J, Adachi E, Jakob C, Tabe Y, Ruethrich M, Borgmann S, Naito T, Wille K, Valenti S, Hower M, Hattori N, Rieg S, Nagaoka T, Jensen BE, Yotsuyanagi H, Hertenstein B, Ogawa H, Wyen C, Kominami E, Roemmele C, Takahashi S, Rupp J, Takahashi K, Hanses F, Hattori K. COVID-19 Severity and Thrombo-Inflammatory Response Linked to Ethnicity. Biomedicine., 2022; 10(10) :2549.
  • K Kurokawa, Y Mitsuishi, N Shimada, Y Kawakami, K Miura, T Miyawaki, T Asao, R Ko, T Shukuya, R Shibayama, S Nojiri, K Takahashi. Association between the efficacy and immune-related adverse events of pembrolizumab and chemotherapy in non-small cell lung cancer patients: a retrospective study. BMC Cancer., 2022; 22(1): 1047.
  • K Takamochi K, K Hara, T Hayashi, S Kohsaka, F Takahashi, Y Suehara, M Shimokawa, K Suzuki. Clinical relevance of PD-L2 expression in surgically resected lung adenocarcinoma. Lung Cancer., 2022; 168: 50-58.
  • S Kishikawa, T Hayashi, T Saito, K Takamochi, K Sasa, Y Suehara, F Takahashi, N Sasahara, S Kohsaka, K Suzuki, T Yao. Distinct properties of pure and mixed-type high-grade fetal lung adenocarcinomas by genetic profiling and transcription factor expression. Virchows Archiv., 2022; 480(3): 609-619.
  • S Otake, S Chubachi, H Namkoong, K Nakagawara, H Tanaka, H Lee, A Morita, T Fukushima, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyama, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Japan C-TF. Clinical clustering with prognostic implications in Japanese COVID-19 patients: report from Japan COVID-19 Task Force, a nation-wide consortium to investigate COVID-19 host genetics. BMC Infect Dis., 2022; 22(1): 735.
  • R Hatano, T Itoh, H Otsuka, H Saeki, A Yamamoto, D Song, Y Shirakawa, S Iyama, T Sato, N Iwao, N Harada, TM Aune, NH Dang, Y Kaneko, T Yamada, C Morimoto, K Ohnuma. Humanized anti-IL-26 monoclonal antibody as a novel targeted therapy for chronic graft-versus-host. Am J Transplant., 2022; 22(12): 2804-2820.
  • H Lee, S Chubachi, H Namkoong, H Tanaka, S Otake, K Nakagawara, A Morita, T Fukushima, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyama, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Japan C-TF. Effects of mild obesity on outcomes in Japanese patients with COVID-19: a nationwide consortium to investigate COVID-19 host genetics. Nutr Diabetes., 2022; 12(1): 38.
  • T Fukushima, S Chubachi, H Namkoong, S Otake, K Nakagawara, H Tanaka, H Lee, A Morita, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyam, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Japan C-TF. U-shaped association between abnormal serum uric acid levels and COVID-19 severity: reports from the Japan COVID-19 Task Force. Int J Infect Dis. 2022;122:747-54.
  • LP McGarvey, SS Birring, AH Morice, PV Dicpinigaitis, ID Pavord, J Schelfhout, AM Nguyen, Q Li, A Tzontcheva, B Iskold, SA Green, C Rosa, DR Muccino, JA Smith, COUGH-1 and COUGH-2 Investigators including(Harada N). Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials. Lancet., 2022; 399(10328): 909-23.
  • S Oizumi, K Takamura, T Harada, M Tachihara, N Morikawa, R Honda, S Watanabe, T Asao, M Kunisaki, T Fukuhara, R Noro, E Kikuchi, Y Tsutani, T Tenma, K Kobayashi, H Dosaka-Akita; North East Japan Study Group, Hokkaido Lung Cancer Clinical Study Group. Phase II study of carboplatin-paclitaxel alone or with bevacizumab in advanced sarcomatoid carcinoma of the lung: HOT1201/NEJ024. Int J Clin Oncol., 2022; 27(4): 676-683.
  • T Asao, S Wtanabe, T Tanaka, S Morita, K Kobayashi. A phase II study of carboplatin and etoposide plus durvalumab for previously untreated extensive-stage small-cell lung cancer (ES-SCLC) patients with a poor performance status (PS): NEJ045A study protocol. BMC Cancer., 2022; 22: 1135.H
  • H Terai, K Soejima, A Shimokawa, H Horinouchi, J Shimizu, T Hase, R Kanemaru, K Watanabe, K Ninomiya, N Aragane, N Yanagitani, Y Sakata, M Seike, D Fujimoto, M Kasajima, A Kubo, S Kusumoto, Y Oyamada, K Fujiwara, M Mori, M Hashimoto, M Shingyoji, M Kodani, J Sakamoto, T Agatsuma, K Kashiwabara, M Inomata, M Tachihara, K Tanaka, K Hayashihara, N Koyama, K Matsui, K Minato, D Jingu, H Sakashita, S Hara, T Naito, A Okada, M Tanahashi, Y Sato, K Asano, T Takeda, K Nakazawa, T Harada, K Shibata, T Kato, E Miyaoka, I Yoshino, A Gemma, T Mitsudomi. Real-World Data Analysis of Pembrolizumab Monotherapy for NSCLC Using Japanese Postmarketing All-Case Surveillance Data. JTO Clin Res Rep., 2022; 3(11): 100404
  • A Yoshimura, T Yamada, M Serizawa, H Uehara, K Tanimura, Y Okuma, A Fukuda, S Watanabe, N Nishioka, T Takeda, Y Chihara, S Takemoto, T Harada, O Hiranuma, Y Shirai, T Shukuya, A Nishiyama, Y Goto, S Shiotsu, K Kunimasa, K Morimoto, Y Katayama, K Suda, T Mitsudomi, S Yano, H Kenmotsu, T Takahashi, K Takayama. High levels of AXL expression in untreated EGFR-mutated non-small cell lung cancer negatively impacts the use of osimertinib. Cancer Sci., 2023; 114(2):606-618.
  • Y Nishioka, Y Toyoda, R Egashira, T Johkoh, Y Terasaki, A Hebisawa, K Abe, T Baba, Y Fujikura, E Fujita, N Hamada, T Handa, Y Hasegawa, K Hidaka, T Hisada, S Hisata, C Honjo, K Ichikado, Y Inoue, S Izumi, M Kato, T Kishimoto, M Okamoto, K Miki, M Mineshita, Y Nakamura, S Sakamoto, M Sano, Y Tsukada, M Yamasue, Y Bando, S Homma, K Hagiwara, T Suda, N Inase. Nationwide retrospective observational study of idiopathic dendriform pulmonary ossification: clinical features with a progressive phenotype. BMJ Open Respir Res., 2022; 9(1): e001337
  • LTH Nguyen, J Zhang, XY Rima, X Wang, KJ Kwak, T Okimoto, J Amann, MJ Yoon, T Shukuya, CL Chiang, N Walters, Y Ma, D Belcher, H Li, AF Palmer, DP Carbone, LJ Lee, E Reátegui. An immunogold single extracellular vesicular RNA and protein (Au SERP) biochip to predict responses to immunotherapy in non-small cell lung cancer patients. J Extracell Vesicles., 2022; 11(9): e12258.
  • K Hotta, T Hida, H Nokihara, M Morise, YH Kim, K Azuma, T Seto, Y Takiguchi, M Nishio, H Yoshioka, T Kumagai, S Watanabe, K Goto, M Satouchi, T Kozuki, T Shukuya,K Nakagawa, T Mitsudomi, N Yamamoto, T Asakawa, T Yoshimoto, S Takata, T Tamura. Final overall survival analysis from the phase III J-ALEX study of alectinib versus crizotinib in ALK inhibitor-naïve Japanese patients with ALK-positive non-small-cell lung cancer. ESMO Open., 2022; 7(4): 100527.
  • C Zhang, C Wang, Z Yang, Y Bai, T Shukuya, ME Poh, S Ekman, J Li, Y Xu, S Deng. Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance. Transl Lung Cancer Res., 2022; 11(5): 786-801.
  • H Kenmotsu, K Wakuda, K Mori, T Kato, S Sugawara, K Kirita, Y Yoneshima, K Azuma, K Nishino, S Teraoka, T Shukuya, K Masuda, H Hayashi, R Toyozawa, S Miura, D Fujimoto, K Nakagawa, N Yamamoto, T Takahashi. Randomized Phase 2 Study of Osimertinib Plus Bevacizumab Versus Osimertinib for Untreated Patients With Nonsquamous NSCLC Harboring EGFR Mutations: WJOG9717L Study. J Thorac Oncol., 2022; 17(9): 1098-1108.
  • T Shukuya, K Takamochi, H Sakurai, K Yoh, T Hishida, M Tsuboi, Y Goto, Y Kudo, Y Ohde, S Okumura, M Taguri, H Kunitoh. Efficacy of Adjuvant Chemotherapy With Tegafur-Uracil in Patients With Completely Resected, Node-Negative NSCLC-Real-World Data in the Era of Molecularly Targeted Agents and Immunotherapy. JTO Clin Res Rep., 2022; 3(5):100320.
  • K Nakagawara, S Chubachi, H Namkoong, H Tanaka, H Lee, S Azekawa, S Otake, T Fukushima, A Morita, M Watase, K Sakurai, T Kusumoto, T Asakura, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyama, Y Nakano, Y Mutoh, Y Suzuki, R Edahiro, K Murakami, Y Sato, Y Okada, R Koike, Y Kitagawa, K Tokunaga, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga. Impact of upper and lower respiratory symptoms on COVID-19 outcomes: a multicenter retrospective cohort study. Respir Res., 2022; 23(1): 315.
  • Y Ozawa, N Yamamoto, K Yamamoto, K Ito, H Kenmotsu, H Hayashi, T Shukuya, D Fujimoto, S Sugawara, S Niho, Y Ohe, H Okamoto, K Nakagawa, K Kiura, I Yoshino, A Gemma. Creation of an Integrated Clinical Trial Database and Data Sharing for Conducting New Research by the Japan Lung Cancer Society. JTO Clin Res Rep., 2022; 3(5): 100317.
  • H Toei, X Zhang, K Seyama, D Yashiro, Y Kuwatsuru, R Kuwatsuru. Prophylactic renal artery embolization before pregnancy in patients with lymphangioleiomyomatosis and renal angiomyolipoma. J Int Med Res., 2022; 50(9): 3000605221123897.
  • K Seyama, M Suzuki, S Tasaka, T Nukiwa, T Sato, S Konno, S Sorrells, J Chen, ME Aragonés, H Minamino. Long-term safety of Prolastin®-C, an alpha1-proteinase inhibitor, in Japanese patients with alpha1-antitrypsin deficiency. Respir Investig., 2022; 60: 831-839.
  • C Inoue, Y Miki, Saito-Koyama R, Kobayashi K, Seyama K, Okada Y, Sasano H. Vasohibin-1 and -2 in pulmonary lymphangioleiomyomatosis (LAM) cells associated with angiogenic and prognostic factors. Pathol Res Pract., 2022;230:153758.
  • H Lee, S Chubachi, H Namkoong, T Asakura, H Tanaka, S Otake, K Nakagawara, A Morita, T Fukushima, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyama, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga K; Japan COVID-19 Task Force. Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force. BMC Infect Dis., 2022; 22(1): 935.
  • M Saita, Y Yan, K Ito, H Sasano, K Seyama, T Naito. Reactogenicity following two doses of the BNT162b2 mRNA COVID-19 vaccine: Real-world evidence from healthcare workers in Japan. J Infect Chemother., 2022; 28:116-119.
  • N Nomura, H Matsumoto, A Yokoyama, Y Nishimura, K Asano, A Niimi, Y Tohda, N Harada, H Nagase, M Nagata, H Inoue, M Kondo, T Horiguchi, N Miyahara, N Hizawa, M Hojo, N Hattori, N Hashimoto, A Yamasaki, T Kadowaki, T Kimura, M Miki, H Taniguchi, M Toyoshima, T Kawamura, O Matsuno, Y Sato, H Sunadome, T Nagasaki, T Oguma, T Hirai; BEXAS study. Nationwide survey of refractory asthma with bronchiectasis by inflammatory subtypes. Respir Res., 2022; 23(1): 365.
2021年
  • Ko R, Shukuya T, Imamura C, Tokito T, Shimada N, Koyama R, Yamada K, Ishii H, Azuma K, Takahashi K. Phase I study of afatinib plus bevacizumab in patients with advanced non-squamous non-small cell lung cancer harboring EGFR mutations. Transl Lung Cancer Res., 2021;10(1): 183-192.
  • Miyawaki T, Wakuda K, Kenmotsu H, Miyawaki E, Mamesaya N, Kobayashi H, Omori S, Ono A, Naito T, Murakami H, Notsu A, Mori K, Harada H, Endo M, Ohde Y, Takahashi K, Takahashi T. Proposing Synchronous Oligometastatic Non-Small Cell Lung Cancer Based on Progression after First-line Systemic Therapy. Cancer Sci., 2021;112(1): 359-368.
  • Kato M, Sasaki S, Tateyama M, Arai Y, Motomura H, Sumiyoshi I, Ochi Y, Watanabe J, Ihara H, Togo S, Takahashi K. Clinical Significance of Continuable Treatment with Nintedanib Over 12 Months for Idiopathic Pulmonary Fibrosis in a Real-World Setting. Drug Design, Development and Therapy., 2021; 15: 223-230.
  • Miyashita Y, Ko R, Shimada N, Mitsuishi Y, Miura K, Matsumoto N, Asao T, Shukuya T, Shibayama R, Koyama R, Takahashi K. Impact of the generation of EGFR-TKIs administered as priortherapy on the effcacy of osimertinib in patients with non-small cell lung cancer harboring EGFR T790M mutation. Thoracic Cancer. 2021;12: 329-338.
  • Wakita M, Idei M, Saito K, Horiuchi Y, Yamatani K, Ishikawa S, Yamamoto T, Igawa G, Hinata M, Kadota K, Kurosawa T, Takahashi S, Saito T, Misawa S, Akazawa C, Naito T, Miida T, Takahashi K, Ai T, Tabe Y. Comparison of the clinical performance and usefulness of five SARS-CoV-2 antibody tests. PLoS One. 2021;16(2): e0246536.
  • Sumiyoshi I, Okabe T, Togo S, Takagi H, Motomura H, Ochi Y, Shimada N, Haraguchi M, Shibayama R, Fujimoto Y, Watanabe J, Iwai M, Kadoya K, Iwakami SI, Takahashi K. High lymphocyte population-related predictive factors for a long-term response in non-small cell lung cancer patients treated with pemetrexed: a retrospective observational study. J Transl Med., 2021; 19(1): 92.
  • Asahina H, Tanaka K, Morita S, Maemondo M, Seike M, Okamoto I, Oizumi S, Kagamu H, Takahashi K, Kikuchi T, Isobe T, Sugio K, Kobayashi K. A Phase II Study of Osimertinib Combined With Platinum Plus Pemetrexed in Patients With EGFR-Mutated Advanced Non-Small-cell Lung Cancer: The OPAL Study (NEJ032C/LOGIK1801). Clin Lung Cancer., 2021; 22(2): 147-151.
  • Sekimoto Y, Suzuki K, Okura M, Hayashi T, Ebana H, Kumasaka T, Mitani K, Nishino K, Okamoto S, Kobayashi E, Takahashi K, Seyama K. Uncommon radiologic computed tomography appearances of the chest in patients with lymphangioleiomyomatosis. Sci Rep., 2021;11(1): 7170.
  • Hiki M, Tabe Y, Ai T, Matsue Y, Harada N, Sugimoto K, Matsushita Y, Matsushita M, Wakita M, Misawa S, Idei M, Miida T, Tamura N, Takahashi K. Naito T. Seroprevalence of anti-SARS-CoV-2 antibodies in Japanese COVID-19 patients. PLoS One., 2021;16(4): e0249449.
  • Udagawa H, Sugiyama E, Harada T, Atagi S, Koyama R, Watanabe S, Nakamura Y, Harada D, Hataji O, Tanaka F, Kida H, Satouchi M, Maeno K, Inoue A, Yoh K, Yamane Y, Urata Y, Yoshioka H, Yanaka T, Goto K. Bevacizumab plus platinum-based chemotherapy in advanced non-squamous non-small-cell lung cancer: a randomized, open-label phase 2 study (CLEAR) Transl Lung Cancer Res. 2021;10(7): 3059-3070.
  • Nishino K, Yoshimatsu Y, Muramatsu T, Sekimoto Y, Mitani K, Kobayashi E, Okamoto S, Ebana H, Okada Y, Kurihara M, Suzuki K, Inazawa J, Takahashi K, Watabe T, Seyama K. Isolation and characterisation of lymphatic endothelial cells from lung tissues affected by lymphangioleiomyomatosis. Sci Rep., 2021;11(1): 8406.
  • Nakamura IT, Ikegami M, Hasegawa N, Hayashi T, Ueno T, Kawazu M, Yagishita S, Goto Y, i Shinno Y, Kojima Y, Takamochi, Takahashi F, Takahashi K, Mano H, Kohsaka S. Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level. Cancer Sci., 2021;112(5): 2006-2019.
  • Iwai M, Tulafu M, Togo S, Kawaji H, Kadoya K, Namba Y, Jin J, Watanabe J, Okabe T, Hidayat M, Sumiyoshi I, Itoh M, Koyama R, Ito Y, Orimo A, Takamochi K, Oh S, Suzuki K, Hayashizaki Y, Yoshida K, Takahashi K. Cancer-associated fibroblast migration in non-small cell lung cancers is modulated by increased integrin α11 expression. Mol Oncol., 2021;15(5): 1507-1527.
  • Tajima M, Togo S, Ko R, Koinuma Y, Sumiyoshi I, Torasawa M, Kikuchi N, Shiraishi A, Sasaki S, Kyogoku S, Kuwatsuru R, Takahashi K. CT Guided Needle Biopsy of Peripheral Lesions-Lesion Characteristics That May Increase the Diagnostic Yield and Reduce the Complication Rate. J Clin Med., 2021;10(9): 2031.
  • Okamoto S, Ebana H, Kurihara M, Mitani K, Kobayashi E, Hayashi T, Sekimoto Y, Nishino K, Otsuji M, Kumasaka T, Takahashi K, Seyama K. Folliculin haploinsufficiency causes cellular dysfunction of pleural mesothelial cells. Sci Rep., 2021;11(1): 10814.
  • Nurwidya F, Takahashi F, Winardi W, Tajima K, Mitsuishi Y, Murakami A, Kobayashi I, Nara T, Hashimoto M, Kato M, Hidayat M, Suina K, Hayakawa D, Asao T, Ko R, Shukuya T, Yae T, Shimada N, Yoshioka Y, Sasaki S, Takahashi K. Zinc-finger E-box-binding homeobox 1 (ZEB1) plays a crucial role in the maintenance of lung cancer stem cells resistant to gefitinib. Thorac Cancer., 2021;12(10): 1536-1548.
  • Sugiyama A, Shiota S, Yanagihara M, Nakayama H, Tsuiki S, Hayashida K, Inoue Y, Takahashi K. The role of long-term continuous positive airway pressure in the progression of obstructive sleep apnoea: A longitudinal cohort study. J Sleep Res., 2021;16: e13374.
  • Takeshige T, Harada N, Harada S, Ishimori A, Katsura Y, Sasano H, Sandhu Y, Matsuno K, Makino F, Ito J, Atsuta R, Akiba H, Takahashi K. Chitin induces steroid-resistant airway inflammation and airway hyperresponsiveness in mice. Allergol Int., 2021;70(3): 343-350.
  • Nakamura Takeda I, Kohsaka S, Ikegami M, Ikeuchi H, Ueno T, Li K, Beyett TS, Koyama T, Shimizu T, Yamamoto N, Takahashi F, Takahashi K, Eck MJ, Mano H. Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer. NPJ Precis Oncol., 2021;5(1): 66.
  • Ohara K, Kinoshita S, Ando J, Azusawa Y, Ishii M, Harada S, Mitsuishi Y, Asao T, Tajima K, Yamamoto T, Takahashi F, Komatsu N, Takahashi K, Ando M. SCLC-J1, a novel small cell lung cancer cell line. Biochem Biophys Rep., 2021;27: 101089.
  • Fukuda H, Seyama K, Ito K, Ai T, Nojiri S, Hori S, Wakita M, Saito K, Shida Y, Nagura R, Hasegawa M, Kanemoto C, Tokuhara M, Okajima K, Yoshikawa Y, Katsuta N, Yamamoto T, Idei M, Horiuchi Y, Yamatani K, Misawa S, Naito T, Miida T, Sato H, Hattori N, Tabe Y, Takahashi K. Author Correction: SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo. Sci Rep., 2021;11(1): 16042.
  • Matsushita Y, Kusaoi M, Hiki M, Murayama G, Abe Y, Nozawa K, Takahashi K, Yamaji K, Tamura N, Naito T. Combination therapy with plasma exchange and glucocorticoid may be effective for severe COVID-19 infection: A retrospective observational study. Ther Apher Dial., 2021;25(4): 390-400.
  • Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, Narita A, Konuma T, Yamamoto K, Akiyama M, Ishigaki K, Suzuki A, Suzuki K, Obara W, Yamaji K, Takahashi K, Asai S, Takahashi Y, Suzuki T, Shinozaki N, Yamaguchi H, Minami S, Murayama S, Yoshimori K, Nagayama S, Obata D, Higashiyama M, Masumoto A, Koretsune Y; FinnGen, Ito K, Terao C, Yamauchi T, Komuro I, Kadowaki T, Tamiya G, Yamamoto M, Nakamura Y, Kubo M, Murakami Y, Yamamoto K, Kamatani Y, Palotie A, Rivas MA, Daly MJ, Matsuda K, Okada Y. A cross-population atlas of genetic associations for 220 human phenotypes. Nat Genet., 2021;53(10): 1415-1424.
  • Hasegawa N, Kohsaka S, Kurokawa K, Shinno Y, Nakamura IT, Ueno T, Kojima S, Kawazu M, Suehara Y, Ishijima M, Goto Y, Kojima Y, Yonemori K, Hayashi T, Saito T, Shukuya T, Takahashi F, Takahashi K, Mano H. Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers. Cancer Sci., 2021;112(10): 4393-4403.
  • Miyawaki T, Kenmotsu H, Yabe M, Kodama H, Nishioka N, Miyawaki E, Mamesaya N, Kobayashi H, Omori S, Wakuda K, Ono A, Deguchi S, Mitsuya K, Naito T, Murakami H, Mori K, Harada H, Hayashi N, Takahashi K, Takahashi T. Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis. Invest New Drugs 2021;39(6): 1732-1741.
  • Miyawaki T, Kenmotsu H, Kodama H, Nishioka N, Miyawaki E, Mamesaya N, Kobayashi H, Omori S, Ko R, Wakuda K, Ono A, Naito T, Murakami H, Mori K, Harada H, Endo M, Takahashi K, Takahashi T. Association between oligo-residual disease and patterns of failure during EGFR-TKI treatment in EGFR-mutated non-small cell lung cancer: a retrospective study. BMC Cancer., 2021;21(1): 1247.
  • Saito K, Ai T, Kawai A, Matsui J, Fukushima Y, Kikukawa N, Kyoutou T, Chonan M, Kawakami T, Hosaka Y, Misawa S, Takagi H, Matsushita Y, Hiki M, Okuzawa A, Hori S, Naito T, Miida T, Takahashi K, Tabe Y. Performance and usefulness of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit for the diagnosis of COVID-19. Sci Rep., 2021;11(1): 23196.
  • Katsuta N, Ito K, Fukuda H, Seyama K, Hori S, Shida Y, Nagura R, Nojiri S, Sato H. Elevated depressive symptoms among newer and younger healthcare workers in Japan during the COVID-19 pandemic. Neuropsychopharmacol Rep. 2021 Dec;41(4):544-547.
  • Takamochi K, Hara K, Hayashi T, Kohsaka S, Takahashi F, Suehara Y, Suzuki K. Programmed death-ligand 1 expression and its associations with clinicopathological features, prognosis, and driver oncogene alterations in surgically resected lung adenocarcinoma. Lung Cancer., 2021;61: 163-170.
  • Sano K, Hayashi T, Suehara Y, Hosoya M, Takamochi K, Kohsaka S, Kishikawa S, Kishi M, Saito S, Takahashi F, Kaneko K, Suzuki K, Yao T, Ishijima M, Saito T. Transcription start site-level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance. Journal of Pathology: Clinical Research., 2021;7(4): 361-374.
  • Hayashi T, Kohsaka S, Takamochi K, Kishikawa S, Sano K, Hara K, Suehara Y, Takahashi F, Saito T, Suzuki K, Yao T. Histological Characteristics of Lung Adenocarcinoma With Uncommon Actionable Alterations: Special Emphasis on MET exon 14 Skipping Alterations. Histopathology., 2021;78(7): 987-999.
  • Kishikawa S, Hayashi T, Saito T, Takamochi K, Kohsaka S, Sano K, Sasahara N, Sasa K, Kurihara T, Hara K, Suehara Y, Takahashi F, Suzuki K, Yao T. Diffuse expression of MUC6 defines a distinct clinicopathological subset of pulmonary invasive mucinous adenocarcinoma. Modern Pathology., 2021;34(4):786-797.
  • Nakagawara K, Namkoong H, Terai H, Masaki K, Tanosaki T, Shimamoto K, Lee H, Tanaka H, Okamori S, Kabata H, Chubachi S, Ikemura S, Kamata H, Yasuda H, Kawada I, Ishii M, Ishibashi Y, Harada S, Fujita T, Ito D, Bun S, Tabuchi H, Kanzaki S, Shimizu E, Fukuda K, Yamagami J, Kobayashi K, Hirano T, Inoue T, Kagyo J, Shiomi T, Ohgino K, Sayama K, Otsuka K, Miyao N, Odani T, Oyamada Y, Masuzawa K, Nakayama S, Suzuki Y, Baba R, Nakachi I, Kuwahara N, Ishiguro T, Mashimo S, Minematsu N, Ueda S, Manabe T, Funatsu Y, Koh H, Yoshiyama T, Saito F, Ishioka K, Takahashi S, Nakamura M, Goto A, Harada N, Kusaka Y, Nakano Y, Nishio K, Tateno H, Edahiro R, Takeda Y, Kumanogoh A, Kodama N, Okamoto M, Umeda A, Hagimura K, Sato T, Miyazaki N, Takemura R, Sato Y, Takebayashi T, Nakahara J, Mimura M, Ogawa K, Shimmura S, Negishi K, Tsubota K, Amagai M, Goto R, Ibuka Y, Hasegawa N, Kitagawa Y, Kanai T, Fukunaga K. Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol. BMJ Open Respir Res., 2021;8(1): e001015.
  • Tanaka H, Lee H, Morita A, Namkoong H, Chubachi S, Kabata H, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan C-TF. Clinical Characteristics of Patients with Coronavirus Disease (COVID-19): Preliminary Baseline Report of Japan COVID-19 Task Force, a Nationwide Consortium to Investigate Host Genetics of COVID-19. Int J Infect Dis., 2021;113: 74-81.
  • COVID-19 Host Genetics Initiative(Takahashi K, Harada N, Takagi H, Nakamura A, et al.). Mapping the human genetic architecture of COVID-19. Nature., 2021;600(7889): 472-477.
  • Kawaguchi K, Hashimoto M, Mikawa R, Asai A, Sato T, Sugimoto M. Protocol for assessing the senescence-associated lung pathologies. STAR Protoc. 2021 Dec 4;2(4):100993.
  • Fujimoto D, Miura S, Yoshimura K, Wakuda K, Oya Y, Yokoyama T, Yokoi T, Asao T, Tamiya M, Nakamura A, Yoshioka H, Haratani K, Teraoka S, Tokito T, Murakami S, Tamiya A, Itoh S, Yokouchi H, Watanabe S, Yamaguchi O, Tomii K, Yamamoto N. Pembrolizumab plus chemotherapy-induced pneumonitis in chemo-naïve patients with non-squamous non-small cell lung cancer: A multicentre, retrospective cohort study. Eur J Cancer., 2021;150: 63-72.
  • Miyawaki T, Kenmotsu H, Harada H, Ohde Y, Chiba Y, Haratani K, Okimoto T, Sakamoto T, Wakuda K, Ito K, Uemura T, Sakata S, Kogure Y, Nishimura Y, Nakagawa K, Yamamoto N. Phase II study of multidisciplinary therapy combined with pembrolizumab for patients with synchronous oligometastatic non-small cell lung cancer TRAP OLIGO study (WJOG11118L). BMC Cancer. 2021 Oct 18;21(1):1121.
  • Wakuda K, Yabe M, Kodama H, Nishioka N, Miyawaki T, Miyawaki E, Mamesaya N, Kobayashi H, Omori S, Ono A, Kenmotsu H, Naito T, Murakami H, Shimizu T, Gon Y, Takahashi T. Long-term outcomes in extensive disease small cell lung cancer patients treated without immune checkpoint inhibitors. Jpn J Clin Oncol., 2021;51(12): 1736-1743.
  • Kodama H, Kenmotsu H, Kawabata T, Notsu A, Yabe M, Nishioka N, Miyawaki E, Miyawaki T, Mamesaya N, Kobayashi H, Omori S, Wakuda K, Ono A, Naito T, Murakami H, Takahashi T. Impact of angiogenesis inhibitor eligibility on the prognosis of patients with non-small cell lung cancer harboring EGFR mutation. Cancer Med., 2021;10(21): 7503-7513.
  • Omori S, Muramatsu K, Kawata T, Miyawaki E, Miyawaki T, Mamesaya N, Kawamura T, Kobayashi H, Nakashima K, Wakuda K, Ono A, Kenmotsu H, Naito T, Murakami H, Sugino T, Takahashi T. Trophoblast cell-surface antigen 2 expression in lung cancer patients and the effects of anti-cancer treatments. J Cancer Res Clin Oncol., 2021;17. doi: 10.1007/s00432-021-03784-3.
  • Mamesaya N, Muramatsu K, Yabe M, Kodama H, Nishioka N, Miyawaki T, Miyawaki E, Kobayashi H, Omori S, Wakuda K, Ono A, Kenmotsu H, Naito T, Murakami H, Harada H, Sugino T, Shimizu T, Gon Y, Takahashi T. Detection of programmed cell death-ligand 1 using 22C3 antibody in patients with unresectable stage III non-small cell lung cancer receiving chemoradiotherapy. Int J Clin Oncol. 2021 Apr;26(4):659-669.
  • Sakamoto S, Kataoka K, Kondoh Y, Kato M, Okamoto M, Mukae H, Bando M, Suda T, Yatera K, Tanino Y, Kishaba T, Hattori N, Taguchi Y, Saito T, Nishioka Y, Kuwano K, Kishi K, Inase N, Sasaki S, Takizawa H, Johkoh T, Sakai F, Homma S; Diffuse Lung Diseases Research Group of the Ministry of Health, Labour and Welfare, Japan. Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial. Eur Respir J., 2021;57: 2000348.
  • Hisata S, Bando M, Homma S, Kataoka K, Ogura T, Izumi S, Sakamoto S, Watanabe K, Saito Y, Shimizu Y, Kato M, Nishioka Y, Hara H, Waseda Y, Tanino Y, Yatera K, Hashimoto S, Mukae H, Inase N; Diffuse Lung Diseases Research Group of the Ministry of Health, Labour and Welfare, Japan. Safety and tolerability of combination therapy with pirfenidone and nintedanib for idiopathic pulmonary fibrosis: A multicenter retrospective observational study in Japan. Respir Investig., 2021;59(6): 819-826.
  • Nakagawa K, Kijima T, Okada M, Morise M, Kato M, Hirano K, Fujimoto N, Takenoyama M, Yokouchi H, Ohe Y, Hida T, Aoe K, Kishimoto T, Hirokawa M, Matsuki H, Kaneko Y, Yamada T, Morimoto C, Takeda M. Phase 2 Study of YS110, a Recombinant Humanized Anti-CD26 Monoclonal Antibody, in Japanese Patients With Advanced Malignant Pleural Mesothelioma. JTO Clin Res Rep., 2021;2(6): 100178.
  • Carrot-Zhang J, Soca-Chafre G, Patterson N, Thorner AR, Nag A, Watson J, Genovese G, Rodriguez J, Gelbard MK, Corrales-Rodriguez L, Mitsuishi Y, Ha G, Campbell JD, Oxnard GR, Arrieta O, Cardona AF, Gusev A, Meyerson M. Genetic Ancestry Contributes to Somatic Mutations in Lung Cancers from Admixed Latin American Populations. Cancer Discov., 2021;11(3): 591-598.
  • Kobayashi K, Terai H, Yasuda H, Hamamoto J, Hayashi Y, Takeuchi O, Mitsuishi Y, Masuzawa K, Manabe T, Ikemura S, Kawada I, Suzuki Y, Soejima K, Fukunaga K. Functional dissection of the KRAS G12C mutation by comparison among multiple oncogenic driver mutations in a lung cancer cell line model. Biochem Biophys Res Commun., 2021;534: 1-7.
  • Sueoka-Aragane N, Nakashima C, Yoshida H, Matsumoto N, Iwanaga K, Ebi N, Nishiyama A, Yatera K, Kuyama S, Fukuda M, Ushijima S, Umeguchi H, Harada D, Kashiwabara K, Suetsugu T, Fujimoto N, Tanaka F, Uramoto H, Yoshii C, Nakatomi K, Koh G, Seki N, Aoe K, Nosaki K, Inoue K, Takamori A, Kawaguchi A. The role of comprehensive analysis with circulating tumor DNA in advanced non-small cell lung cancer patients considered for osimertinib treatment. Cancer Med., 2021;10(12): 3873-3885.
  • Ikarashi D, Okimoto T, Shukuya T, Onagi H, Hayashi T, Sinicropi-Yao SL, Amann JM, Nakatsura T, Kitano S, Carbone DP. Comparison of Tumor Microenvironments Between Primary Tumors and Brain Metastases in Patients With NSCLC. JTO Clin Res Rep., 2021;2(10): 100230.
  • Sata M, Sasaki S, Oikado K, Saito Y, Tominaga J, Sakai F, Kato T, Iwasawa T, Kenmotsu H, Kusumoto M, Baba T, Endo M, Fujiwara Y, Sugiura H, Yanagawa N, Ito Y, Sakamoto T, Ohe Y, Kuwano K. Treatment and relapse of interstitial lung disease in nivolumab-treated patients with non-small cell lung cancer. Cancer Sci., 2021;112(4): 1506-1513.
  • Saito Y, Sasaki S, Oikado K, Tominaga J, Sata M, Sakai F, Kato T, Iwasawa T, Kenmotsu H, Kusumoto M, Baba T, Endo M, Fujiwara Y, Sugiura H, Yanagawa N, Ito Y, Sakamoto T, Ohe Y, Kuwano K. Radiographic features and poor prognostic factors of interstitial lung disease with nivolumab for non-small cell lung cancer. Cancer Sci., 2021;112(4): 1495-1505.
  • Shimoda Y, Yoshida T, Shirasawa M, Mizuno T, Jo H, Matsumoto Y, Shinno Y, Okuma Y, Goto Y, Horinouchi H, Yamamoto N, Yatabe Y, Ohe Y, Motoi N. Smoking History Predicts High Presence of TILs and Efficacy of PD-1 Blockade in PD-L1 Expression-negative Non-small Cell Lung Cancer Patients. Anticancer Res., 2021;41(11): 5739-5747.
  • Takagi S, Sasaki Y, Koike S, Takemoto A, Seto Y, Haraguchi M, Ukaji T, Kawaguchi T, Sugawara M, Saito M, Funauchi Y, Ae K, Matsumoto S, Fujita N, Katayama R. Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis. Oncogene., 2021;40(36): 5548-5558.
  • Harada N, Ito J, Takahashi K. Clinical effects and immune modulation of biologics in asthma. Respir Investig., 2021;59: 389-396.
  • Abe S, Ito J, Harada S, Sasano H, Ueda S, Sandhu Y, Takeshige T, Katsura Y,Harada N, Takahashi K. A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction. Allergy Asthma Clin Immunol. 2021; 17(1): 36.
  • Ueda S, Shukuya T, Hayashi T, Suzuki M, Kondo A, Aai Y, Takeshige T, Ninomiya H, Takahashi K. Transformation from adenocarcinoma to squamous cell lung carcinoma with MET amplification after lorlatinib resistance: A case report. Thorac Cancer., 2021;12(5): 715-719.
  • Miyashita Y, Hara M, Iwakami SI, Matsuda H, Iwakami N, Takahashi K. Sarcoidosis with marked necrosis in enlarged lymph nodes mimics mycobacterial infection: a case report. J Med Case Rep., 15(1):178, 2021
  • Matsuda H, Hara M, Iwakami S, Takahashi K. EML4-ALK positive lung adenocarcinoma with skeletal muscle metastasis in the right calf which was treatable with lorlatinib after resistance to treatment with alectinib. BMJ Case Rep., 2021;14(4): e240295.
  • Haraguchi M, Harada N, Watanabe J, Yoshikawa H, Shirai Y, Komura M, Koyama M, Ito J, Tsukune Y, Horimoto Y, Hayashi T, Nagaoka T, Uekusa T, Takahashi K. Disseminated nontuberculous mycobacteriosis and fungemia after second delivery in a patient with MonoMAC syndrome/GATA2 mutation: a case report. BMC Infect Dis., 2021;21(1): 502.
  • Kato M, Mori M, Miura K, Asao T, Motomura H, Nishino K, Ko R, Koyama R, Hayashi T, Takahashi K. Dramatic, significant metabolic response to a one-time pembrolizumab treatment following a relapse of pre-existing organizing pneumonia in a patient with advanced non-small cell lung cancer: A case report. Thorac Cancer., 2021; 12(22): 3076-3079.
  • Ishida M, Hiraoka M, Yaguchi A, Sugano K, Adachi N, Itoga T, Ishiguro T, Onishi H. Naldemedine-induced opioid withdrawal syndrome with severe psychiatric symptoms in an advanced cervical cancer patient without brain metastasis. Palliat Support Care., 27: 1-3, 2021
2020年
  • Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H, Takahashi K. Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation. Thorac Cancer. 11(1):140-149, 2020 Jan
  • Hosomi Y, Morita S, Sugawara S, Kato T, Fukuhara T, Gemma A, Takahashi K, Fujita Y, Harada T, Minato K, Takamura K, Hagiwara K, Kobayashi K, Nukiwa T, Inoue A; North-East Japan Study Group. Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study. J Clin Oncol. 38(2):115-123, 2020 Jan
  • Ko Y, Asakawa K, Tobino K, Oguma T, Hirai T, Takada T, Takahashi K, Seyama K; Multicenter Lymphangioleiomyomatosis Sirolimus Trial for Safety Study Group. Quantitative analysis of computed tomography of the lungs in patients with lymphangioleiomyomatosis treated with sirolimus. Heliyon 6(2):e03345. 2020 Feb 6
  • Tateishi K, Ko R, Shukuya T, Okuma Y, Watanabe S, Kuyama S, Murase K, Tsukita Y, Ashinuma H, Nakagawa T, Uematsu K, Nakao M, Mori Y, Kaira K, Mouri A, Miyabayashi T, Sakashita H, Matsumoto Y, Tanigawa T, Koizumi T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group. Clinical Outcomes of Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma: A Retrospective Analysis of 191 Patients from the NEJ023 Study. Oncologist 25(4): e668-e674. 2020 Apr
  • Sekine I, Shintani Y, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K, Dosaka-Akita H, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I. A Japanese lung cancer registry study on demographics and treatment modalities in medically treated patients. Cancer Sci. 111(5):1685-1691, 2020 May
  • Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K, Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis. Eur Respir J. 55(5):1902150, 2020 May
  • Okamoto S, Suzuki K, Hayashi T, Muraki K, Nagaoka T, Nishino K, Sekimoto Y, Sasaki S, Takahashi K, Seyama K. Transbronchial lung biopsy for the diagnosis of lymphangioleiomyomatosis: the severity of cystic lung destruction assessed by the modified Goddard scoring system as a predictor for establishing the diagnosis. Orphanet J Rare Dis 15(1):125, 2020 May
  • Kohsaka S, Hayashi T, Nagano M, Ueno T, Kojima S, Kawazu M, Shiraishi Y, Kishikawa S, Suehara Y, Takahashi F, Takahashi K, Suzuki K, Takamochi K, Mano H. Identification of Novel CD74-NRG2αFusion From Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers. J Thorac Oncol 15(6):948-961, 2020 Jun
  • Kozuki T, Nogami N, Hataji O, Tsunezuka Y, Seki N, Harada T, Fujimoto N, Bessho A, Takamura K, Takahashi K, Satouchi M, Kato T, Shukuya T, Yamashita N, Okamoto H, Shinkai T, Thoracic Oncology Research Group. Open-label, multicenter, randomized phase II study on docetaxel plus bevacizumab or pemetrexed plus bevacizumab for treatment of elderly (aged ≥75 years) patients with previously untreated advanced non-squamous non-small cell lung cancer: TORG1323. Transl Lung Cancer Res 9(3): 459-470, 2020 Jun
  • Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Terao C, Amariuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y, Sakata Y, Kohno T, Shiraishi K, Momozawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y, Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N, Minami S, Yamaguchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A, Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T, Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K, Murakami Y, Nakamura Y, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nat Genet. 52(7):669-679, 2020 Jun
  • Ihara H, Mitsuishi Y, Kato M, Takahashi F, Tajima K, Hayashi T, Hidayat M, Winardi W, Wirawan A, Hayakawa D, Kanamori K, Matsumoto N, Yae T, Sato T, Sasaki S, Takamochi K, Suehara Y, Ogura D, Niwa SI, Suzuki K, Takahashi K. Nintedanib Inhibits Epithelial-Mesenchymal Transition in A549 Alveolar Epithelial Cells Through Regulation of the TGF-β/Smad Pathway. Respir Investig 58(4): 275-284, 2020 Jul
  • Kobayashi K, Soejima K, Fukunaga K, Shintani Y, Sekine I, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K, Yamamoto N, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I, and on behalf of the Group on behalf of the Japanese Joint Committee of Lung Cancer Registry. Key prognostic factors for EGFR-mutated non-adenocarcinoma lung cancer patients in the Japanese Joint Committee of Lung Cancer Registry Database. Lung Cancer 146: 236-243, 2020 Aug
  • Igawa S, Naoki K, Shintani Y, Sekine I, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K, Yamamoto N, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I. Survival and Prognostic Factors in Elderly Patients Receiving Second-line Chemotherapy for Relapsed Small-Cell Lung Cancer: Results from the Japanese Joint Committee of Lung Cancer Registry. Lung Cancer. 146: 160-164, 2020 Aug
  • Harada N, Harada S, Ito J, Atsuta R, Hori S, Takahashi K. Mobile Health App for Japanese Adult Patients With Asthma: Clinical Observational Study. J Med Internet Res. 22(8):e19006, 2020 Aug 14
  • Miyawaki T, Kenmotsu H, Mori K, Miyawaki E, Mamesaya N, Kawamura T, Kobayashi H, Omori S, Wakuda K, Ono A, Naito T, Murakami H, Harada H, Endo M, Ohde Y, Takahashi K, Takahashi T. Association Between Clinical Tumor Burden and Efficacy of Immune Checkpoint Inhibitor Monotherapy for Advanced Non-Small-Cell Lung Cancer. Clin Lung Cancer. 21(5): e405-e414, 2020 Sep
  • Hayashi T, Kohsaka S, Takamochi K, Hara K, Kishikawa S, Sano K, Takahashi F, Suehara Y, Saito T, Takahashi K, Suzuki K, Yao T. Clinicopathological characteristics of lung adenocarcinoma with compound EGFR mutations. Hum Pathol. 103:42-51, 2020 Sep
  • Takei S, Ihara H, Togo S, Nakamura A, Fujimoto Y, Watanabe J, Kurokawa K, Shibayama K, Sumiyoshi I, Ochi Y, Iwai M, Okabe T, Chonan M, Misawa S, Ohsaka A, Takahashi K. The synergetic effect of Imipenem-clarithromycin combination in the Mycobacteroides abscessus complex. BMC Microbiol. 20(1):316, 2020 Oct 19
  • Okuma Y, Ko R, Shukuya T, Tateishi K, Imai H, Iwasawa S, Miyauchi E, Kojima T, Fujita Y, Hino T, Yamanda S, Suzuki T, Fukuizumi A, Sakakibara T, Harada T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group. Prognostic factors for patients with metastatic or recurrent thymic carcinoma receiving palliative-intent chemotherapy. Lung Cancer. 148:122-128, 2020 Oct
  • Kato M, Takahashi F, Sato T, Mitsuishi Y, Tajima K, Ihara H, Nurwidya F, Baskoro H, Murakami A, Kobayashi I, Hidayat M, Shimada N, Sasaki S, Mineki R, Fujimura T, Kumasaka T, Niwa S, Takahashi K. Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway. Drug Des Devel Ther. 14: 4593-4603, 2020 Oct 29
  • Tsuboshima K, Kurihara M, Yamanaka T, Watanabe K, Matoba Y, Seyama K. Does a gender have something to do with clinical pictures of primary spontaneous pneumothorax? Gen Thorac Cardiovasc Surg. 68(8):741-745, 2020.
  • Suzuki K, Seyama K, Ebana H, Kumasaka T, Kuwatsuru R. Quantitative analysis of cystic lung diseases by use of paired inspiratory and expiratory CT: estimation of the extent of cyst-airway communication and evaluation of diagnostic utility. Radiology: Cardiothoracic Imaging. 2: e190097, 2020
  • Suzuki E, Kurihara M, Tsuboshima K, Watanabe K, Okamoto S, Seyama K. The effects of total pleural covering on pneumothorax recurrence and pulmonary function in lymphangioleiomyomatosis patients without history of pleurodesis or thoracic surgeries for pneumothorax. J Thorac Dis in press, 2020.
  • Miyazaki K, Togo S, Okamoto R, Idiris A, Kumagai H, Miyagi Y. Collective cancer cell invasion in contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix. Cancer Sci. 2020 Sep 26.
  • Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Harada N, Atsuta R, Fujisawa T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez FD, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in asthma: practical considerations. Eur Respir J 2020; 56: 2002809.
  • Mikawa R, Sato T, Suzuki Y, Baskoro H, Kawaguchi K, Sugimoto M. p19Arf exacerbates cigarette smoke-induced pulmonary dysfunction. Biomolecules 10(3), 462. (2020)
  • Llabata P, Mitsuishi Y, Choi PS, Cai D, Francis JM, Torres-Diz M, Udeshi ND, Golomb L, Wu Z, Zhou J, Svinkina T, Aguilera-Jimenez E, Liu Y, Carr SA, Sanchez- Cespedes M, Meyerson M, Zhang X. Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma. Mol Cancer Res. 2020 Apr;18(4):574-584.
  • Sakamoto S, Kataoka K, Kondo Y, Kato M, Okamoto M, Mukae H, Bando M, Suda T, Yatera K, Tanino Y, Kishaba T, Hattori N, Taguchi Y, Saito T, Nishioka Y, Kuwano K, Kishi K, Inase N, Sasaki S, Takizawa H, Johkoh T, Sakai F, Homma S; Diffuse Lung Diseases Research Group of the Ministry of Health, Labour and Welfare, Japan. Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial. Eur Respir J. 2020 Jul 23:2000348.
  • Tanaka K, Morita S, Ando M, Yokoyama T, Nakamura A, Yoshioka H, Ishiguro T, Miura S, Toyozawa R, Oguri T, Daga H, Ko R, Bessho A, Tashihara M, Iwamoto Y, Hirano K, Nakanishi Y, Nakagawa K, Yamamoto N, Okamoto I. A randomized phase 3 study of maintenance therapy with S-1 plus best supportive care versus best supportive care after induction therapy with carboplatin plus S-1 for advanced or relapsed squamous cell carcinoma of the lung (WJOG7512L). Cancer 2020; 125: 3648-3656.
  • Shukuya T, Ghai V, Amann JM, Okimoto T, Shilo K, Kim TK, Wang K, Carbone DP. Circulating MicroRNAs and Extracellular Vesicle-Containing MicroRNAs as Response Biomarkers of Anti-programmed Cell Death Protein 1 or Programmed Death-Ligand 1 Therapy in NSCLC. J Thorac Oncol. 2020 Nov;15(11):1773-1781.
  • Shukuya T, Oyanagi J, Serizawa M, Watanabe M, Yamamoto N, Koh Y. Hypoxia Inducible Factor-1α Inhibition in Von Hippel Lindau-mutant Malignant Pleural Mesothelioma Cells. Anticancer Res. 2020 Apr;40(4):1867-1874.
  • Yamauchi M, Nakayama H, Shiota S, Ohshima Y, Terada J, Nishijima T, Kosuga M, Kitamura T, Tachibana N, Oguri T, Shirahama R, Aoki Y, Ishigaki K, Sugie K, Yagi T, Muraki H, Fujita Y, Takatani T, Muro S. Potential patient screening for late-onset Pompe disease in suspected sleep apnea: a rationale and study design for a Prospective Multicenter Observational Cohort Study in Japan (PSSAP-J Study). Sleep Breath. 2020 Aug 18. Online ahead of print.
  • Sata N, Inoshita A, Suda S, Shiota S, Shiroshita N, Kawana F, Suzuki Y, Matsumoto F, Ikeda K, Kasai T. Clinical, polysomnographic, and cephalometric features of obstructive sleep apnea with AHI over 100. Sleep Breath. 2020 Nov 17. Online ahead of print.
  • Nakagawa K, Hida T, Nokihara H, Morise M, Azuma K, Kim Y.K, Seto T, Takiguchi Y, Nishio M, Yoshioka H, Kumagai T, Hotta K, Watanabe S, Goto K, Satouchi M, Kozuki T, Koyama R, Mitsudomi T, Yamamoto N, Asakawa T, Hayashi M, Hasegawa W, Tamura T.Final progression-free survival results from the J-ALEX study of alectinib versus crizotinib in ALK-positive non-small-cell lung cancer. Lung Cancer., 2020 Jan; 139: 195-199.
  • Nakazawa Y, Sakashita A, Kaizu M, Abo H, Ise Y, Shinada Y, Sugano K, Yamashiro A, Akizuki N, Kato M. A Self-Check Program Targeting Quality Improvement in a Hospital-Based Palliative Care Consultation Team, Japanese Society for Palliative Medicine: Issues Regarding Team Activities Identified through the Plan-Do-Check-Act Cycle. J Palliat Med. 2020 Mar; 23(3):359-367
  • Matsuda Y, Tanimukai H, Inoue S, Inada S, Sugano K, Hasuo H, Yoshimura M, Wada S, Dotani C, Adachi H, Okamoto Y, Takeuchi M, Fujisawa D, Kako J, Sasaki C, Kishi Y, Akizuki N, Inagaki M, Uchitomi Y, Matsushima E, Okuyama T. JPOS/JASCC clinical guidelines for delirium in adult cancer patients: a summary of recommendation statements. Jpn J Clin Oncol 2020 May; 50(5): 586-593
  • Kogami M, Suzuki S, Nanjo Y, Ikeda K, Tamura N, Sasaki S, Morimoto S. Complication of coronavirus disease 2019 during remission induction therapy against anti-MDA5 antibody-positive dermatomyositis. Rheumatol Adv Pract. 4(2): rkaa068, 2020 Nov
  • Sugiyama AI, Shiota S, Yamada T, Ito J, Suzuki K, Takahashi K. Sleep-related breathing disorders associated with the characteristics of underlying congenital rare diseases of Moebius syndrome and Poland syndrome. Respirol Case Rep 8(5): e00579, 2020 May
  • Jingo K, Harada N, Nishioki T,Torasawa M,Yamada T, Asao T, Takagi T,Takeshige T, Ito J, Takahashi K. Anaphylaxis to three humanized antibodies for severe asthma: A case study. Allergy Asthma Clin Immunol. 10;16:46. eCollection 2020 Jun
  • Kato Y, Kato M, Ihara H, Hayakawa E, Shibayama K, Miura K, Yamada T, Mitsuishi Y, Shukuya T, Ito J, Matsunaga T, Sato T, Suzuki K, Takahashi K. Hermansky-Pudlak syndrome-associated pneumothorax with rapid progression of respiratory failure: a case report. BMC Pulm Med. 20(1):259, 2020 Oct
  • Nishioki T, Kato M, Kataoka S, Miura K, Nagaoka T, Takahashi K. Atezolizumab‐induced fulminant type 1 diabetes mellitus occurring four months after treatment cessation. Respirology Case Reports. 8(9):doi.org/10.1002/rcr2.685, 20020 Oct
  • Kurokawa K, Harada N, Sasano H, Takahagi H, Takei S, Nakamura A, Kamada K, Yoshida A, Kikuchi K, Takahashi K. Pulmonary infection due to fluoroquinolone-resistant Mycolicibacterium fortuitum: a case report. BMC Infectious Diseases. 20: 866, 2020 Nov
  • Ochi Y, Kato M, Fujioka M, Hayashi M, Takagi H, Takahashi K. Thrombocytopaenia during nintedanib treatment in a patient with idiopathic pulmonary fibrosis. Respirol Case Rep. 2020, 8: e00628.
  • Kurata K, Matsumoto H, Jimbo N, Yakushijin K, Yamamoto K, Ito M, Nakamachi Y, Matsuoka H, Saegusa J, Seyama K, Itoh T, Minami H. Lymphoplasmacytic lymphoma in a patient with Birt-Hogg-Dubé syndrome. Int J Hematol. 2020 Dec;112(6):864-870.
  • Hayashi T, Takamochi K, Kohsaka S, Kishikawa S, Suehara Y, Takahashi F, Suzuki K, Saito T. Spontaneous transformation from EGFR/PTEN co-mutated lung adenocarcinoma to small cell carcinoma in lymph node metastasis. Pathol Int 70(5):295-299 (2020)
  • Kumakawa Y, Hirano Y, Sueyoshi K, Ishihara T, Kondo Y, Kawasaki T, Takeuchi Y, Nakamura Y, Ishikawa K, Watanabe Y, Saito W, Matsuda S, Nakazawa T, Sasaki S, Okamoto K, Hiroshi T. Late i.v. steroid treatment for severe COVID-19-induced acute respiratory distress syndrome: a case report. Acute Med Surg., 7(1): e569, 2020 Sep
  • Hayama N, Ihara H, Honma Y, Itoigawa Y, Kaira K, Fujii M: Severe gastritis due to pembrolizumab treatment in a lung cancer patient. Respirol Case Rep. 8(7) : e00636, 2020 Oct
2019年
  • Tsutsumi T, Nagaoka T, Yoshida T, Wang L, Kuriyama S, Suzuki Y, Nagata Y, Harada N, Kodama Y, Takahashi F, Morio Y, Takahashi K. Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation. PLoS one 24;14(7):e0214697. eCollection 2019.
  • Kadoya K, Togo S, Tulafu M, Namba Y, Iwai M, Watanabe J, Okabe T, Jin J, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Takeda T, Kondo N, Takahashi K. Specific features of fibrotic lung fibroblasts highly sensitive to fibrotic processes mediated via TGF-β-ERK5 interaction. Cell Physiol Biochem. 52(4):822-837, 2019 Jun
  • Tajima K, Matsuda S, Yae T, Drapkin BJ, Morris R, Boukhali M, Niederhoffer K, Comaills V, Dubash T, Nieman L, Guo H, Magnus NKC, Dyson N, Shioda T, Haas W, Haber DA, Maheswaran S. SETD1A protects from senescence through regulation of the mitotic gene expression program. Nat Commun. 2019 Jun 28;10(1):2854.
  • Shukuya T, Yamada T, Koenig MJ, Xu J, Okimoto T, Li F, Amann JM, Carbone DP. The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer. J Thorac Oncol. 2019 Jun;14(6):1061-1076. Epub 2019
  • Kitajima S, Ivanova E, Guo S, Yoshida R, Campisi M, Sundararaman SK, Tange S, Mitsuishi Y, Thai TC, Masuda S, Piel BP, Sholl LM, Kirschmeier PT, Paweletz CP, Watanabe H, Yajima M, Barbie DA. Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer. Cancer Discov. 2019 Jan;9(1):34-45. Epub 2018 Oct 8.
  • Kohsaka S, Tatsuno K, Ueno T, Nagano M, Shinozaki-Ushiku A, Ushiku T, Takai D, Ikegami M, Kobayashi H, Kage H, Ando M, Hata K, Ueda H, Yamamoto S, Kojima S, Oseto K, Akaike K, Suehara Y, Hayashi T, Saito T, Takahashi F, Takahashi K, Takamochi K, Suzuki K, Nagayama S, Oda Y, Mimori K, Ishihara S, Yatomi Y, Nagase T, Nakajima J, Tanaka S, Fukayama M, Oda K, Nangaku M, Miyazono K, Miyagawa K, Aburatani H, Mano H. Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens. Cancer Sci. 110(4):1464-1479, 2019 Apr
  • Koike K, Berdyshev EV, Mikosz AM, Bronova IA, Bronoff AS, Jung JP, Beatman EL, Ni K, Cao D, Scruggs AK, Serban KA, Petrache I. Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema. Am J Respir Crit Care Med. 2019 Nov 1;200(9):1113-1125. doi: 10.1164/rccm.201812-2311OC.
  • Kato M, Sasaki S, Nakamura T, Kurokawa K, Yamada T, Ochi Y, Ihara H, Takahashi F, Takahashi K. Gastrointestinal adverse effects of nintedanib and the associated risk factors in patients with idiopathic pulmonary fibrosis. Scientific Reports 19;9(1):12062. 2019.
  • Kato M, Sasaki S, Kurokawa K, Nakamura T, Yamada T, Sasano H, Arano N, Komura M, Ihara H, Nagashima O, Shiota S, Takahashi F, Takahashi K. Usual interstitial pneumonia pattern in the lower lung lobes as a prognostic factor in idiopathic pleuroparenchymal fibroelastosis. Respiration. 97(4):319-328, 2019 Jan
  • Tateishi K, Ko R, Shukuya T, Okuma Y, Watanabe S, Kuyama S, Murase K, Tsukita Y, Ashinuma H, Nakagawa T, Uematsu K, Nakao M, Mori Y, Kaira K, Mouri A, Miyabayashi T, Sakashita H, Matsumoto Y, Tanigawa T, Koizumi T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group. Clinical Outcomes of Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma: A Retrospective Analysis of 191 Patients from the NEJ023 Study. Oncologist. 2019 Nov 26. pii: theoncologist.2019-0593. [Epub ahead of print]
  • Seyama K, Nukiwa T, Sato T, Suzuki M, Konno S, Takahashi K, Nishimura M, Steinmann K, Sorrells S, Chen J, Hayashi KI. Safety and pharmacokinetics of Alpha-1 MP (Prolastin®-C) in Japanese patients with alpha1-antitrypsin (AAT) deficiency. Respir Investig. 57(1):89-96, 2019 Jan
  • Yamaguchi Y, Shiota S, Kusunoki Y, Hamaya H, Ishii M, Kodama Y, Akishita M, Kida K, Takahashi K, Nagase T, Fukuchi Y. Polysomnographic features of low arousal threshold in overlap syndrome involving obstructive sleep apnea and chronic obstructive pulmonary disease. Sleep Breath. 2019 Jan 26. [Epub ahead of print]
  • Tanabe Y, Harada N, Ito J, Matsuno K, Takeshige T, Harada S, Takemasa M, Kotajima M, Ishimori A, Katsura Y, Makino F, Atsuta R, Takahashi K. Difference between two exhaled nitric oxide analyzers, NIOX VERO® electrochemical hand-held analyzer and NOA280i® chemiluminescence stationary analyzer. J Asthma. 56(2):167-172, 2019 Feb
  • Kuwasaki E, Nagaoka T, Ihara H, Tsutsumi T, Nakamura A, Yoshikawa H, Yoshida T, Watanabe J, Ichikawa M, Koyama R, Shimada N, Takahashi K. Age is an independent predictor in pathological diagnosis of sarcoidosis: a retrospective analysis of diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration. J Thorac Dis. 11(5):2175-2180, 2019 May
  • Hidayat M, Mitsuishi Y, Takahashi F, Tajima K, Yae T, Miyahara K, Hayakawa D, Winardi W, Ihara H, Koinuma Y, Wirawan A, Nurwidya F, Kato M, Kobayashi I, Sasaki S, Takamochi K, Hayashi T, Suehara Y, Moriyama M, Moriyama H, Habu S, Takahashi K. Role of FBXW7 in the quiescence of gefitinib-resistant lung cancer stem cells in EGFR-mutant non-small cell lung cancer. Bosn J Basic Med Sci. 2019 May 28. [Epub ahead of print]
  • Jin J, Togo S, Kadoya K, Tulafu M, Namba Y, Iwai M, Watanabe J, Nagahama K, Okabe T, Hidayat M, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Sasaki S, Tominaga S, Takahashi K. Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1. Respir Res. 20(1):119, 2019 Jun 11
  • Nanjo Y, Newstead MW, Aoyagi T, Zeng X, Takahashi K, Yu FS, Tateda K, Standiford TJ. Overlapping Roles for Interleukin-36 Cytokines in Protective Host Defense against Murine Legionella pneumophila Pneumonia. Infect Immun. 19;87(1). pii: e00583-18. 2019
  • Zuoyou L, Shiota S, Morio Y, Sugiyama A, Sekiya M, Iwakami SI, Ienaga H, Fukuchi Y, Takahashi K. Borderline pulmonary hypertension associated with chronic hypercapnia in chronic pulmonary disease. Respir Physiol Neurobiol. 2019 Apr;262:20-25. Epub 2019
  • Ihara H, Kikuchi K, Taniguchi H, Fujita S, Tsuruta Y, Kato M, Mitsuishi Y, Tajima K, Kodama Y, Takahashi F, Takahashi K, Azuma N. 23-valent pneumococcal polysaccharide vaccine improves survival in dialysis patients by preventing cardiac events. Vaccine. 2019 Oct 8;37(43):6447-6453. Epub 2019
  • Karasutani K, Baskoro H, Sato T, Arano N, Suzuki Y, Mitsui A, Shimada N, Kodama Y, Seyama K, Fukuchi Y, Takahashi K. Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice. J Vis Exp. 2019 Sep 26;(151).
  • Shoji T, Konno S, Niida Y, Ogi T, Suzuki M, Shimizu K, Hida Y, Kaga K, Seyama K, Naka T, Matsuno Y, Nishimura M. Familial multifocal micronodular pneumocyte hyperplasia with a novel splicing mutation in TSC1: Three cases in one family. PLoS One. 2019 Feb 22;14(2):e0212370. eCollection 2019.
  • Oba S, Inaba Y, Shibuya T, Oshima J, Seyama K, Kobayashi T, Kunugita N, Ino T. Changes in oxidative stress levels during two weeks of smoking cessation treatment and their association with nutritional characteristics in Japanese smokers. Exp Ther Med. 2019 Apr;17(4):2757-2764. Epub 2019
  • Tsuyama S, Saito T, Akazawa Y, Yanai Y, Yatagai N, Akaike K, Hayashi T, Suehara Y, Takahashi F, Takamochi K, Hashimoto T, Kajiyama Y, Tsurumaru M, Fukunaga T, Yao T. Molecular and clinicopathological analyses of esophageal carcinosarcoma with special reference to morphological change. Virchows Archiv ;475(4):415-424. Epub 2019 Aug 23.
  • Suehara Y, Okubo T, Kurihara T, Hayashi T, Kohsaka S, Kazuno S, Sano K, Hasegawa N, Miura Y, Akaike K, Kim Y, Takamochi K, Takahashi F, Ueno T, Kaneko K, Saito T. Protein Expression Profiles Corresponding to Histological Changes with Denosumab Treatment in Giant Cell Tumors of Bone. Proteomics Clin Appl. e1800147. (2019)
  • Miyazaki K, Oyanagi J, Hoshino D, Togo S, Kumagai H, Miyagi Y. Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix. Sci Rep. 2019 Jan 22;9(1):292.
  • Maruyama N, Takai T, Kamijo S, Suchiva P, Ohba M, Takeshige T, Suzuki M, Hara M, Matsuno K, Harada S, Harada N, Nakae S, Sudo K, Okuno T, Yokomizo T, Ogawa H, Okumura K, Ikeda S. Cyclooxygenase inhibition in mice heightens adaptive- and innate-type responses against inhaled protease allergen and IL-33. Allergy. 2019 Nov;74(11):2237-2240. Epub 2019
  • Mizugaki H, Hamada A, Shibata T, Hosoda F, Nakamura H, Okuma Y, Shukuya T, Umemura S, Horiike A, Fukui T, Kogure Y, Daga H, Urata Y, Yamada K, Saeki S, Fujisaka Y, Nakamura Y, Sato M, Yoshida T, Hotta T, Oizumi S, Fujiwara Y, Ohe Y, Fujiwara Y. Exploration of germline variants responsible for adverse events of crizotinib in anaplastic lymphoma kinase-positive non-small cell lung cancer by target-gene panel sequencing. Lung Cancer. 2019 Feb;128:20-25.
  • Yoh K, Takamochi K, Shukuya T, Hishida T, Tsuboi M, Sakurai H, Goto Y, Yoshida K, Ohde Y, Okumura S, Ohashi Y, Kunitoh H. Pattern of care in adjuvant therapy for resected Stage I non-small cell lung cancer: real-world data from Japan. Jpn J Clin Oncol. 2019 Jan 1;49(1):63-68.
  • Kenmotsu H, Yoh K, Mori K, Ono A, Baba T, Fujiwara Y, Yamaguchi O, Ko R, Okamoto H, Yamamoto N, Ninomiya T, Ogura T, Kato T. Phase II study of nab-paclitaxel + carboplatin for patients with non-small-cell lung cancer and interstitial lung disease. Cancer Sci. 2019 Dec;110(12):3738-3745.
  • Nakashima K, Kimura M, Akamatsu H, Daga H, Imai H, Taira T, Ko R, Hisamatsu Y, Nishino K, Sugimoto T, Miyashita Y, Takahashi T. Osimertinib for patients with EGFR T790M mutation-positive non-small-cell lung cancer and a poor performance status. Jpn J Clin Oncol. 2019 Jul 1;49(7):671-675.
  • Okazaki S, Umene K, Yamasaki J, Suina K, Otsuki Y, Yoshikawa M, Minami Y, Masuko T, Kawaguchi S, Nakayama H, Banno K, Aoki D, Saya H, Nagano O. Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma. Cancer Sci. 2019 Nov;110(11):3453-3463.
  • Koike K, Beatman EL, Schweitzer KS, Justice MJ, Mikosz AM, Ni K, Clauss MA, Petrache I. Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L558-L566.
  • Baba T, Akai F. S, Kato T, Kusumoto M, Kenmotsu H, Sugiura H, Tominaga J, Oikado K, Sata M, Endo M, Yanagawa N, Sasaki S, Iwasawa T, Saito Y, Fujiwara Y, Ohe Y, Yamazaki N, Sakamoto T, Koshiba T, Kuwano K. Radiologic features of pneumonitis associated with nivolumab in non-small-cell lung cancer and malignant melanoma. Future Oncol., 2019 Jun; 15(16): 1911-1920.
  • Murata K, Inoue Y, Kaiho M, Nakazawa T, Sasaki S, Miyake K, Matsuda S, Tanaka H. Genomic analysis of antibiotic resistance for Acinetobacter baumannii in a critical care center. Acute Med Surg., 2019 Jul; 7(1): e445.
  • Kato M, Yamada T, Kataoka S, Arai Y, Miura K, Ochi Y, Ihara H, Koyama R, Sasaki S, Takahashi K. Prognostic differences among patients with idiopathic interstitial pneumonias with acute exacerbation of varying pathogenesis: a retrospective study. Respir Res. 2019 Dec 18;20(1):287.
  • Sasaki S, Kato M, Nakamura K, Namba Y, Nagashima O, Takahashi K. Management of skin sarcoidosis with minocycline monotherapy. Respirol Case Rep. 2019 Mar 13;7(4):e00413, 2019 Mar eCollection 2019 May.
  • Kurokawa K, Asao T, Ko R, Nagaoka T, Suzuki K, Takahashi K. Severe mediastinitis over a month after endobronchial ultrasound-guided transbronchial needle aspiration. Respirol Case Rep. 2019 Apr 9;7(5):e00426. eCollection 2019 Jul
  • Kurokawa K, Hara H, Iwakami S, Genda T, Iwakami N, Miyashita Y, Fujioka M, Sasaki S, Takahashi K. Cholestatic Liver Injury Induced by Pembrolizumab in a Patient with Lung Adenocarcinoma. Intern Med 58(22):3283-3287. Epub 2019 Nov 15.
2018年
  • Yasuda M, Harada N, Harada S, Ishimori A, Katsura Y, Itoigawa Y, Matsuno K, Makino F, Ito J, Ono J, Tobino K, Akiba H, Atsuta R, Izuhara K, Takahashi K. Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E. Allergy Asthma Clin Immunol 2018; 14: 72.
  • Kanemaru R, Takahashi F, Kato M, Mitsuishi Y, Tajima K, Ihara H, Hidayat M, Wirawan A, Koinuma Y, Hayakawa D, Yagishita S, Ko R, Sato T, Harada N, Kodama Y, Nurwidya F, Sasaki S, Niwa SI, Takahashi K. Dasatinib Suppresses TGFbeta-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Inhibits Pulmonary Fibrosis. Lung 2018;196(5):531-541.
  • Glowacka WK, Jain H, Okura M, Maimaitiming A, Mamatjan Y, Nejad R, Farooq H, Taylor MD, Aldape K, Kongkham P.
    5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma. Acta Neuropathol. 2018 Apr;135(4):617-634.
  • Horimoto Y, Tokuda E, Murakami F, Uomori T, Himuro T, Nakai K, Orihata G, Iijima K, Togo S, Shimizu H, Saito M. Analysis of circulating tumour cell and the epithelial mesenchymal transition (EMT) status during eribulin-based treatment in 22 patients with metastatic breast cancer: a pilot study. J Transl Med. 2018 Oct 20;16(1):287. doi: 10.1186/s12967-018-1663-8.
  • Miharu Kato, Yumiko Kanehiro, Kaku Yoshimi, Yuzo Kodama, Mitsuaki Sekiya, Tadashi Sato, Kazuhisa Takahashi, Kuniaki Seyama. COPD assessment test as a possible tool for evaluating health-related quality of life in lymphangioleiomyomatosis Respiratory Investigation, 2018;56;480-488.
  • Miharu Kato, Mitsuaki Sekiya, Yohei Suzuki, Tadashi Sato, Masako Ichikawa, Yuzo Kodama, Kuniaki Seyama, Eri Aikawa-Hirasawa, Kazuhisa Takahashi. Evaluation of Physical Activity in Patients with Chronic Obstructive Pulmonary Disease Using an Accelerometer with Tapestry-Style Display Capability. Juntendo Medical Journal 2018;64: (4): 286-294.
  • Kato M, Sasaki S, Kurokawa K, Nakamura T, Yamada T, Sasano H, Arano N, Komura M, Ihara H, Nagashima O, Shiota S, Takahashi F, Takahashi K. Usual Interstitial Pneumonia Pattern in the Lower Lung Lobes as a Prognostic Factor in Idiopathic Pleuroparenchymal Fibroelastosis. Respiration. 2018 Dec 6:1-10. doi: 10.1159/000494061.
  • Takahashi K, Ueda S, Kobayashi T, Nishiyama A, Fujisawa Y, Sugaya T, Shiota S, Takahashi K, Gohda T, Horikoshi S, Suzuki Y. Chronic intermittent hypoxia-mediated renal sympathetic nerve activation in hypertension and cardiovascular disease. Sci Rep. 2018 Dec 18;8(1):17926. doi: 10.1038/s41598-018-36159-9.
  • Mikawa R, Suzuki Y, Baskoro H, Kanayama K, Sugimoto K, Sato T, Sugimoto M. Elimination of p19ARF-expressing cells protects against pulmonary emphysema in mice. Aging Cell, 2018;17(5):e12827.
  • Kobayashi K, Miki Y, Saito R, Adachi K, Seyama K, Okada Y, Sasano H. Roles of human epidermal growth factor receptor family in pulmonary lymphangioleiomyomatosis Hum Pathol. 2018 Nov;81:121-130.
  • Oishi H, Watanabe T, Matsuda Y, Noda M, Ejima Y, Saiki Y, Seyama K, Kondo T, Okada Y. Single lung transplantation for lymphangioleiomyomatosis: a single-center experience in Japan. Surg Today. 2018 Oct;48(10):944-950.
  • Callea F, Giovannoni I, Francalanci P, Boldrini R, Faa G, Medicina D, Nobili V, Desmet VJ, Ishak K, Seyama K, Bellacchio E. Mineralization of alpha-1-antitrypsin inclusion bodies in Mmalton alpha-1-antitrypsin deficiency. Orphanet J Rare Dis. 2018 May 16;13(1):79.
  • Mizobuchi T, Kurihara M, Ebana H, Yamanaka S, Kataoka H, Okamoto S, Kobayashi E, Kumasaka T, Seyama K. A total pleural covering of absorbable cellulose mesh prevents pneumothorax recurrence in patients with Birt-Hogg-Dubé syndrome. Orphanet J Rare Dis. 2018 May 15;13(1):78.
  • Iwabuchi C, Ebana H, Ishiko A, Negishi A, Mizobuchi T, Kumasaka T, Kurihara M, Seyama K. Skin lesions of Birt-Hogg-Dubé syndrome: Clinical and histopathological findings in 31 Japanese patients who presented with pneumothorax and/or multiple lung cysts. J Dermatol Sci. 2018 Jan;89(1):77-84.
  • Mina Y,Norihiro H. Characterization of tenascin-C as a novel biomarker for asthma: Utility of tenascin-C in combination with periostin or immunoglobulin E. Allergy Asthma Clin Immunol. 2018;14:72.
  • Watanabe M, Kenmotsu H, Ko R, Wakuda K, Ono A, Imai H, Taira T, Naito T, Murakami H, Abe M, Endo M, Nakajima T, Koh Y, Takahashi T. Isolation and molecular analysis of circulating tumor cells from lung cancer patients using a microfluidic chip type cell sorter. Cancer Sci. 2018; 109(8): 2539-2548.
  • Kamei R, Yoshimura K, Yoshino S, Inoue M, Asao T, Fuse M, Wada S, Kuramasu A, Furuya-Kondo T, Oga A, Iizuka N, Suzuki N, Maeda N, Watanabe Y, Matsukuma S, Iida M, Takeda S, Ueno T, Yamamoto N, Fukagawa T, Katai H, Sasaki H, Hazama S, Oka M, Nagano H. Expression levels of UL16 binding protein 1 and natural killer group 2 member D affect overall survival in patients with gastric cancer following gastrectomy. Oncol Lett 2018; 15(1): 747-754.
  • Otani H, Takahashi A, Kato K, Kano N, Watanabe D, Yoshioka R, Fujikawa S, Hongo T, Sugahara R, Hisanaga M, Hirai Y, Mita T, Suzuki K, Takahashi K. Aim and future perspectives of the tropical medicine association of Juntendo University through the activity of the 53rd south east asia research group. Juntendo Medical Journal, 2018; 64(1): 59-63
  • Ebana H, Mizobuchi T, Kurihara M, Kobayashi E, Haga T, Okamoto S, Takahashi K, Seyama K. Novel clinical scoring system to identify patients with pneumothorax with suspicion for Birt-Hogg-Dubé syndrome. Respirology, 2018; 23(4):414-418
  • Ebana H, Hayashi T, Mitani K, Kobayashi E, Kumasaka T, Mizobuchi T, Kurihara M, Takahashi F, Takahashi K, Seyama K. Oxidized regenerated cellulose induces pleural thickening in patients with pneumothorax: possible involvement of the mesothelial-mesenchymal transition. Surg Today, 2018; 48(4):462-472
  • Ihara H, Harada N, Shimada N, Kanamori K, Hayashi T, Uekusa T, Takahashi K. A Case of Malignant Pleural Mesothelioma with Bone Marrow Metastases. Intern Med, 2018; 57(17):2541-2545
  • Ko R, Shukuya T, Okuma Y, Tateishi K, Imai H, Iwasawa S, Miyauchi E, Fujiwara A, Sugiyama T, Azuma K, Muraki K, Yamasaki M, Tanaka H, Takashima Y, Soda S, Ishimoto O, Koyama N, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group. Prognostic Factors and Efficacy of First-Line Chemotherapy in Patients with Advanced Thymic Carcinoma: A Retrospective Analysis of 286 Patients from NEJ023 Study. Oncologist, 2018; 23(10):1210-1217
  • Iwakami N, Iwakami SI, Hara M, Sekiya M, Dambara T, Takahashi K. The diagnostic yield using ultrasound-guided needle-aspiration for subpleural primary lung cancer is not affected by the radiological properties of the lesions resulting from computed tomography. Respir Investig. 2018; 56(3):238-242
  • Watanabe J, Togo S, Sumiyoshi I, Namba Y, Suina K, Mizuno T, Kadoya K, Motomura H, Iwai M, Nagaoka T, Sasaki S, Hayashi T, Uekusa T, Abe K, Urata Y, Sakurai F, Mizuguchi H, Kato S, Takahashi K. Clinical features of squamous cell lung cancer with anaplastic lymphoma kinase (ALK)-rearrangement: a retrospective analysis and review. Oncotarget. 2018; 9(35):24000-24013
  • Homma S, Bando M, Azuma A, Sakamoto S, Sugino K, Ishii Y, Izumi S, Inase N, Inoue Y, Ebina M, Ogura T, Kishi K, Kishaba T, Kido T, Gemma A, Goto Y, Sasaki S, Johkoh T, Suda T, Takahashi K, Takahashi H, Taguchi Y, Date H, Taniguchi H, Nakayama T, Nishioka Y, Hasegawa Y, Hattori N, Fukuoka J, Miyamoto A, Mukae H, Yokoyama A, Yoshino I, Watanabe K; Ministry of Health, Labour and Welfare, the Study Group on Diffuse Pulmonary Disorders, Scientific Research/Research on Intractable Diseases, and Japanese Respiratory Society. Japanese guideline for the treatment of idiopathic pulmonary fibrosis. Respir Investig. 2018; 56(4):268-291
  • Yamada T, Iwakami SI, Hara SAM, Iwakami N, Nakamura A, Suzuki Y, Sasaki SI, Takahashi K. Disseminated non-tuberculous mycobacterial infection caused by anti-interferon-γ autoantibodies in a patient of very advanced age. Geriatr Gerontol Int. 2018; 18(7):1132-1133
  • Baskoro H, Sato T, Karasutani K, Suzuki Y, Mitsui A, Arano N, Nurwidya F, Kato M, Takahashi F, Kodama Y, Seyama K, Takahashi K. Regional heterogeneity in response of airway epithelial cells to cigarette smoke. BMC Pulm Med. 2018; 4;18(1):148
  • Matsuno K, Harada N, Harada S, Takeshige T, Ishimori A, Itoigawa Y, Katsura Y, Kodama Y, Makino F, Ito J, Atsuta R, Akiba H, Takahashi K. Combination of TWEAK and TGF-β1 induces the production of TSLP, RANTES, and TARC in BEAS-2B human bronchial epithelial cells during epithelial-mesenchymal transition. Exp Lung Res. 2018; 44(7):332-343
  • Komura M, Yagishita S, Nakamura K, Arano N, Takeshige T, Muraki K, Nagashima O, Izumi H, Tomita S, Sasaki S, Takahashi K. A Case of a Pregnant Woman Diagnosed as Having ALK-rearranged Lung Adenocarcinoma.In Vivo. 2018; 32(5):1205-1209
    F
  • Hara M, Iwakami SI, Sumiyoshi I, Yoshida T, Sasaki S, Takahashi K. Hydrocarbon pneumonitis caused by the inhalation of wood preservative. Respirol Case Rep. 2018; 26;6(9):e00379
  • Nanjo Y, Newstead MW, Aoyagi T, Zeng X, Takahashi K, Yu FS, Tateda K, Standiford TJ. Overlapping Roles for Interleukin-36 Cytokines in Protective Host Defense against Murine Legionella pneumophila Pneumonia. Infect Immun. 2018; 19;87(1)
  • Suina K, Tsuchihashi K, Yamasaki J, Kamenori S, Shintani S, Hirata Y, Okazaki S, Sampetrean O, Baba E, Akashi K, Mitsuishi Y, Takahashi F, Takahashi K, Saya H, Nagano O. Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling. Cancer Sci. 2018; 109(12):3874-3882
  • Ishii M, Suehara Y, Kohsaka S, Hayashi T, Kazuno S, Tanabe Y, Akaike K, Mukaihara K, Kim Y, Okubo T, Takamochi K, Takahashi F, Kaneko K, Saito T. Proteomic signatures corresponding to the SS18/SSX fusion gene in synovial sarcoma. Oncotarget 25;9(101):37509-37519. (2018)
  • Akazawa Y, Saito T, Hayashi T, Yanai Y, Tsuyama S, Akaike K, Suehara Y, Takahashi F, Takamochi K, Murakami T, Watanabe S. Yao T. Next-generation sequencing analysis for gastric adenocarcinoma with enteroblastic differentiation: emphasis on the relationship with hepatoid adenocarcinoma. Human pathology 78:79-88. (2018)
  • Akaike K, Suehara Y, Kohsaka S, Hayashi T, Tanabe Y, Kazuno S, Mukaihara K, Toda-Ishii M, Okubo T, Hayashi Y, Takamoch K, Takahashi F, Kaneko K, Saito T. PPP2R1A regulated by PAX3/FOXO3 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma. Oncotarget 18;9(38):25206-25215. (2018)
  • Hayashi T, Takamochi K, Yanai Y, Mitani K, Tomita H, Mogushi K, Suehara Y, Takahashi F, Suzuki K, Saito T, Yao T. Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p40. Human pathology 78:177-181. (2018)
  • Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, Giannakis M, Hahn WC1, Cherniack AD, Meyerson M. Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor. Cancer Discov. 2018 Jan;8(1):108-125.
  • Hirano T, Ohkouchi S, Tode N, Kobayashi M, Ono M, Satoh T, Mitsuishi Y, Watanabe A, Tabata M, Irokawa T, Ogawa H, Sugiura H, Kikuchi T, Akasaka K, Tazawa R, Inoue Y, Nakata K, Kurosawa H, Ichinose M. Peripheral alveolar nitric oxide concentration reflects alveolar inflammation in autoimmune pulmonary alveolar proteinosis. ERJ Open Res. 2018 Mar 23;4(1). pii: 00071-2017.
  • Okazaki S, Shintani S, Hirata Y, Suina K, Semba T, Yamasaki J, Umene K, Ishikawa M, Saya H, Nagano O. Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cells. Oncotarget. 2018 Sep 18;9(73):33832-33843.
  • hiota M, Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, Suematsu M. Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival. Nat Commun. 2018 Apr 19;9(1):1561.
  • Yamada T, Amann JM, Tanimoto A, Taniguchi H, Shukuya T, Timmers C, Yano S, Shilo K, Carbone DP. Histone Deacetylase Inhibition Enhances the Antitumor Activity of a MEK Inhibitor in Lung Cancer Cells Harboring RAS Mutations. Mol Cancer Ther. 2018 Jan;17(1):17-25.
2017年
  • Kohsaka S, Nagano M, Ueno T, Suehara Y, Hayashi T, Shimada N, Takahashi K, Suzuki K, Takamochi K, Takahashi F, Mano H.
    A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer.
    Sci Transl Med. 2017 Nov 15;9(416).
  • Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, Giannakis M, Hahn WC, Cherniack AD, Meyerson M.
    Somatic super-enhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor.
    Cancer Discov. 2017 Sep 29. pii: CD-17-0532.
  • Hida T, Nokihara H, Kondo M, Kim YH, Azuma K, Seto T, Takiguchi Y, Nishio M, Yoshioka H, Imamura F, Hotta K, Watanabe S, Goto K, Satouchi M, Kozuki T, Shukuya T, Nakagawa K, Mitsudomi T, Yamamoto N, Asakawa T, Asabe R, Tanaka T, Tamura T.
    Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.
    Lancet. 2017 Jul 1;390(10089):29-39.
  • Okamoto S, Togo S, Nagata I, Shimizu K, Koinuma Y, Namba Y, Ito J, Uekusa T, Takahashi K. Lung adenocarcinoma expressing receptor for advanced glycation end-products with primary systemic AL amyloidosis: a case report and literature review. BMC Cancer. 17(1):22. doi: 10.1186/s12885-016-3009-3, 2017 Jan 3.265
  • Namba Y, Togo S, Tulafu M, Kadoya K, Nagahama KY, Taka H, Kaga N, Orimo A, Liu XD, Takahashi K. Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes. Respiratory Research. 18(1):46, 2017 Mar 11
  • Ishimori A, Harada N, Chiba A, Harada S, Matsuno K, Makino F, Ito J, Ohta S, Ono J, Atsuta R, Izuhara K, Takahashi K, Miyake S. Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma. Allergol Int. 66(2): 302-309, 2017 Apr 2.355
  • Nishino K, Yoshimi K, Shibuya T, Hayashi T, Mitani K, Kobayashi E, Ichikawa M, Asao T, Suzuki Y, Sato T, Shiota S, Kodama Y, Takahashi K, Seyama K. Protein-losing Enteropathy Caused by Intestinal or Colonic Lymphangiectasia Complicated by Sporadic Lymphangioleiomyomatosis: A Report of Two Cases.Intern Med. 56(8):943-948, 2017 Apr 15.
  • Arano N, Morio Y, Futagawa T, Hashizume A, Nagashima O, Sasaki SI, Tominaga S, Takahashi K. Lung metastases from cutaneous adenoid cystic carcinoma 23 years after initial treatment. Respir Med Case Rep. 21:121-123, 2017 Apr 19
  • Yamada T, Amann JM, Tanimoto A, Taniguchi H, Shukuya T, Timmers C, Yano S, Shilo K, Carbone DP.
    Histone deacetylase inhibition enhances the antitumor activity of a MEK inhibitor in lung cancer cells harboring RAS mutations.
    Mol Cancer Ther. 2017 Oct 27. pii: molcanther.0146.2017.
  • Shukuya T, Patel S, Shane-Carson K, He K, Bertino EM, Shilo K, Otterson GA, Carbone DP.
    Lung Cancer Patients with Germline Mutations Detected by Next-Generation Sequencing and/or Liquid Biopsy.
    J Thorac Oncol. 2017 Oct 5. pii: S1556-0864(17)32764-8.
  • Otsubo K, Nosaki K, Imamura CK, Ogata H, Fujita A, Sakata S, Hirai F, Toyokawa G, Iwama E, Harada T, Seto T, Takenoyama M, Ozeki T, Mushiroda T, Inada M, Kishimoto J, Tsuchihashi K, Suina K, Nagano O, Saya H, Nakanishi Y, Okamoto I.
    Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non-small-cell lung cancer.
    Cancer Sci. 2017 Sep;108(9):1843-1849.
  • Ohta T, Mita M, Hishinuma S, Ishii-Nozawa R, Takahashi K, Shoji M. Inhibition of ectopic arginine vasopressin production by phenytoin in the small cell lung cancer cell line Lu-165. Original Research. 2017 April 28. doi: 10.3389/fendo.2017.00094
  • Ai T, Yuri M, Tabe Y, Kakimoto A, Morishita S, Tsuchiya K, Takamochi K, Kodama Y, Takahashi F, Shigeki M, Horii T, Suzuki K, Takahashi K, Miida T, Ohsaka A. Comparison of the Analytical Performance Between cobas EGFR Assay and PCR-Clamp Method in the Detection of EGFR Mutations in Japanese Non-Small Cell Lung Cancer Patients. Clin Lab. 63(5):1021-1026, 2017 May 1
  • Nakamura K, Kato M, Shukuya T, Mori K, Sekimoto Y, Ihara H, Kanemaru R, Ko R, Shibayama R, Tajima K, Koyama R, Shimada N, Nagashima O, Takahashi F, Sasaki S, Takahashi K. Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study.BMC Cancer. 17(1):302.doi: 10.1186/s12885-017-3285-6. 2017 May 2
  • Togo S, Katagiri N, Namba Y, Tulafu M, Nagahama K, Kadoya K, Takamochi K, Oh S, Suzuki K, Sakurai F, Mizuguchi H, Urata Y, Takahashi K. Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients. Oncotarget. 8(21):34884-34895, 2017 May 23
  • Okamoto S, Komura M, Terao Y, Kurisaki-Arakawa A, Hayashi T, Saito T, Togo S, Shiokawa A, Mitani K, Kobayashi E, Kumasaka T, Takahashi K, Seyama K. Pneumothorax caused by cystic and nodular lung metastases from a malignant uterine perivascular epithelioid cell tumor (PEComa).Respir Med Case Rep. 22:77-82, 2017 Jun 27
  • Asao T, Fujiwara Y, Itahashi K, Kitahara S, Goto Y, Horinouchi H, Kanda S, Nokihara H, Yamamoto N, Takahashi K, Ohe Y. Sequential Use of Anaplastic Lymphoma Kinase Inhibitors in Japanese Patients With ALK-Rearranged Non-Small-Cell Lung Cancer: A Retrospective Analysis. Clin Lung Cancer. 18(4): e251-e258, 2017 Jul 3.030
  • Takaeshige T, Harada N, Sekimoto Y, Kanemaru R, Tsutsumi T, Matsuno K, Shiota S, Masuda A, Gotoh A, Asahina M, Uekusa T, Takahashi K. Pulmonary Intravascular large B-cell lymphoma(IVLBCL) disguised as an Asthma exacerbation in a patient with asthma. Intern Med. 56: 1885-1891, 2017
  • Kodama Y, Kishimoto Y, Muramatsu Y, Tatebe J, Yamamoto Y, Hirota N, Itoigawa Y, Atsuta R, Koike K, Sato T, Aizawa K, Takahashi K, Morita T, Homma S, Seyama K, Ishigami A. Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome, and bronchial asthma. Clin Respir J. 2015 Dec 14. doi: 10.1111/crj.12436. [Epub ahead of print] 1.512
  • Nurwidya F, Takahashi F, Kato M, Baskoro H, Hidayat M, Wirawan A, Takahashi K. CD44 silencing decreases the expression of stem cell-related factors induced by transforming growth factor β1 and tumor necrosis factor α in lung cancer: Preliminary findings. Bosn J Basic Med Sci. 2017 Apr 24. doi: 10.17305/bjbms.2017.1966. [Epub ahead of print]
  • Sandhu Y, Ando K, Takekawa H, Takagi H, Hirama M, Kido K, Takahashi K.
    Safety of Bronchoscopy for Patients Undergoing Hemodialysis.
    Respir Investig. 2017 Mar;55(2):173-175.
  • Yoshikawa H, Fujii M, Iwakami SI, Takeda I, Hayakawa D, Takahashi K.
    Chylothorax ascribed to chronic heart failure in a woman of very advanced years.
    Geriatr Gerontol Int. 2017 Jul;17(7):1133-1135.
  • Suzuki Y, Sato T, Sugimoto M, Baskoro H, Karasutani K, Mitsui A, Nurwidya F, Arano N, Kodama Y, Hirano SI, Ishigami A, Seyama K, Takahashi K.
    Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
    Biochem Biophys Res Commun. 2017 Oct 7;492(1):74-81.
  • Honma Y, Togo S, Shimizu K, Tulafu M, Hayashi T, Uekusa T, Tominaga S, Kido K, Fujimoto Y, Nanba Y, Takamochi K, Oh S, Suzuki K, Takahashi K.
    Expression of thymidylate synthase predicts clinical outcomes of S-1-based chemotherapy in squamous cell lung cancer.
    Oncol Lett. 2017 Sep;14(3):3319-3326.
  • Jotatsu T, Yagishita S, Tajima K, Takahashi F, Mogushi K, Hidayat M, Wirawan A, Ko R, Kanemaru R, Shimada N, Mitani K, Saito T, Takamochi K, Suzuki K, Kohsaka S, Kojima S, Mukae H, Yatera K, Takahashi K.
    LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.
    Biochem Biophys Rep. 2016 Dec 1;9:86-94.
  • Ebana H, Mizobuchi T, Kurihara M, Kobayashi E, Haga T, Okamoto S, Takahashi K, Seyama K.
    Novel clinical scoring system to identify patients with pneumothorax with suspicion for Birt-Hogg-Dubé syndrome.
    Respirology. 2017 Sep 27. doi: 10.1111/resp.13191. [Epub ahead of print]
  • Ebana H, Hayashi T, Mitani K, Kobayashi E, Kumasaka T, Mizobuchi T, Kurihara M, Takahashi F, Takahashi K, Seyama K.
    Oxidized regenerated cellulose induces pleural thickening in patients with pneumothorax: possible involvement of the mesothelial-mesenchymal transition.
    Surg Today. 2017 Oct 12. doi: 10.1007/s00595-017-1597-4. [Epub ahead of print]
  • Nakamura K, Kato M, Miyashita Y, Nagashima O, Sasaki S, Tominaga S, Takahashi K.
    Development of interstitial pneumonia during treatment with eribulin: a case report.
    BMC Res Notes. 2017 Nov 6;10(1):557.
  • Tobino K, Hirai T, Johkoh T, Fujimoto K, Kawaguchi A, Tomiyama N, Takahashi K, Seyama K.
    Difference of the progression of pulmonary cysts assessed by computed tomography among COPD, lymphangioleiomyomatosis, and Birt-Hogg-Dubé syndrome.
    PLoS One. 2017 Dec 8;12(12):e0188771.
  • Takamochi K, Takahashi F, Suehara Y, Kitano S, Sato E, Kohsaka S, Hayashi T, Mano H, Suzuki K.
    DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel Lung Cancer.
    Lung Cancer 110:26-31. (2017)
  • Iwabuchi C, Ebana H, Ishiko A, Negishi A, Mizobuchi T, Kumasaka T, Kurihara M, Seyama K.
    Skin lesions of Birt-Hogg-Dubé syndrome: Clinical and histopathological findings in 31 Japanese patients who presented with pneumothorax and/or multiple lung cysts.
    J Dermatol Sci. 2017 Nov 2. pii: S0923-1811(17)30462-0.
  • Gupta N, Finlay GA, Kotloff RM, Strange C, Wilson KC, Young LR, Taveira-DaSilva AM, Johnson SR, Cottin V, Sahn SA, Ryu JH, Seyama K, Inoue Y, Downey GP, Han MK, Colby TV, Wikenheiser-Brokamp KA, Meyer CA, Smith K, Moss J, McCormack FX; ATS Assembly on Clinical Problems.
    Lymphangioleiomyomatosis Diagnosis and Management: High-Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guideline.
    Am J Respir Crit Care Med. 2017 Nov 15;196(10):1337-1348.
  • Kitamura N, Seyama K, Inoue Y, Nagai K, Suzuki M, Moriyama H, Takada T, Tazawa R, Hirai T, Mishima M, Hayashida M, Hirose M, Arai T, Sugimoto C, Hattori N, Watanabe K, Tamada T, Akazawa K, Tanaka T, Nakata K.
    Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator-initiated prospective study.
    Pharmacoepidemiol Drug Saf. 2017 Oct;26(10):1182-1189.
  • Onodera K, Sugiura H, Yamada M, Koarai A, Fujino N, Yanagisawa S, Tanaka R, Numakura T, Togo S, Sato K, Kyogoku Y, Hashimoto Y, Okazaki T, Tamada T, Kobayashi S, Yanai M, Miura M, Hoshikawa Y, Okada Y, Suzuki S, Ichinose M.
    Decrease in an anti-ageing factor, growth differentiation factor 11, in chronic obstructive pulmonary disease.
    Thorax. 2017 Oct;72(10):893-904.
  • Saito M, Fujiwara Y, Asao T, Honda T, Shimada Y, Kanai Y, Tsuta K, Kono K, Watanabe S, Ohe Y, Kohno T.
    The genomic and epigenomic landscape in thymic carcinoma.
    Carcinogenesis. 2017 Oct 26;38(11):1084-1091.
  • Konagai A, Yoshimura K, Hazama S, Yamamoto N, Aoki K, Ueno T, Fujioka M, Iijima H, Kato M, Uchida M, Wada T, Inoue M, Asao T, Fuse M, Wada S, Kuramasu A, Kamei R, Takeda S, Yamamoto S, Yoshino S, Oka M, Nagano H.
    Correlation Between NKG2DL Expression and Antitumor Effect of Protein-bound Polysaccharide-K in Tumor-bearing Mouse Models.
    Anticancer Res. 2017 Aug;37(8):4093-4101.
  • Nakamichi S, Horinouchi H, Asao T, Goto Y, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Ito Y, Watanabe SI, Ohe Y.
    Comparison of Radiotherapy and Chemoradiotherapy for Locoregional Recurrence of Non-small-cell Lung Cancer Developing After Surgery.
    Clin Lung Cancer. 2017 Nov;18(6):e441-e448.
  • Okuma HS, Horinouchi H, Kitahara S, Asao T, Sunami K, Goto Y, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Ohe Y.
    Comparison of Amrubicin and Weekly Cisplatin/Etoposide/Irinotecan in Patients With Relapsed Small-cell Lung Cancer.
    Clin Lung Cancer. 2017 Mar;18(2):234-240.
  • Shitara K, Doi T, Nagano O, Fukutani M, Hasegawa H, Nomura S, Sato A, Kuwata T, Asai K, Einaga Y, Tsuchihashi K, Suina K, Maeda Y, Saya H, Ohtsu A.
    Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407).
    Gastric Cancer. 2017 Nov;20(6):1004-1009.
  • Ikari J, Nelson AJ, Obaid J, Giron-Martinez A, Ikari K, Makino F, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Demeo D, Feghali-Bostwick C, Holz O, Rabe K, Liu X, Rennard SI.
    Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease.
    PLoS One. 2017 Sep 7;12(9):e0184039.
2016年
  • Ando K, Okada Y, Akiba M, Kondo T, Kawamura T, Okumura M, Chen F, Date H, Shiraishi T, Iwasaki A, Yamasaki N, Nagayasu T, Chida M, Inoue Y, Hirai T, Seyama K, Mishima M and the Respiratory Failure Research Group of the Japanese Ministry of Health, Labour, and Welfare.
    Lung transplantation for lymphangioleiomyomatosis in Japan.
    PLos One 2016; 11(1): e0146749.
  • Fujita A, Ando K, Kobayashi E, Mitani K, Okudera K, Nakashima M, Miyatake S, Tsurusaki Y, Saitsu H, Seyama K, Miyake N, Matsumoto N.
    Detection of low-prevalence somatic TSC2 mutations in sporadic pulmonary lymphangioleiomyomatosis tissues by deep sequencing.
    Hum Genet. 2016,135(1):61-8.
  • Gunji-Niitsu Y, Kumasaka T, Kitamura S, Hoshika Y, Hayashi T, Tokuda H, Morita R, Kobayashi E, Mitani K, Kikkawa M, Takahashi K, Seyama K.
    Benign clear cell sugar tumor of the lung in a patient with Birt-Hogg-Dub? syndrome: a case report.
    BMC Med Genet. 2016,17(1):85.
  • Jotatsu, T., Yagishita, S., Tajima, K., Takahashi, F., Mogushi, K., Hidayat, M., Wirawan, A., Ko, R., Kanemaru, R., Shimada, N., Mitani, K., Saito, T., Takamochi, K., Suzuki, K., Kohsaka, S., Kojima, S., Mukae, H., Yatera, K., and Takahashi, K.LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.
    Biochemical and biophysical research communications. 2016;473(1):125-132.
    Kato M, Sasaki S, Sekimoto Y, Arano N, Jo H, Suina K, Kuriyama S, Muraki K, Nagashima O, Yoshioka Y, Tominaga S, Takahashi K.
    Loxoprofen-induced interstitial pneumonia: a case report.
    J Med Case Rep. 2016,10(1):128.
  • Ko R, Kenmotsu H, Serizawa M, Koh Y, Wakuda K, Ono A, Taira T, Naito T, Murakami H, Isaka M, Endo M, Nakajima T, Ohde Y, Yamamoto N, Takahashi K, Takahashi T
    Frequency of EGFR T790M mutatoin and multimutational profiles of rebiopsy samples from non-small cell lung cancer developing acquired resistance to EGFR tryosine kinase inhibitors in Japanese patients
    BMC cancer, 2016; 16(1): 864
  • Kobayashi I, Takahashi F, Nurwydia F, Nara T, Hashimoto M, Murakami A, Yagishita S, Tajima K, Hidayat M, Shimada N, Suina K, Yoshioka Y, Sasaki S, Moriyama M, Moriyama H, Takahashi K.
    Oct4 plays a crucial role in the maintenance of gefitinib-resistant lung cancer stem cells.
    Biochem Biophys Res Commun. 2016,22;473(1):125-32.
  • Koyama R, Takahashi K.
    Non-Small-Cell lung cancer treatment: cytotoxic chemotherapy, molecular targeted therapy, and immunotherapy.
    untendo Medical Journal,2016, 62(1): 7-12.
  • Kato M, Morio Y, Matsunaga T, Shiraishi A, Uekusa T, Takahashi K.
    Bronchial-pulmonary arterial fistula with primary racemose hemangioma.
    Respirol Case Rep. 2016,4(2):e00148.
  • Nurwidya F, Takahashi F, Takahashi K.
    Gefitinib in the treatment of nonsmall cell lung cancer with activating epidermal growth factor receptor mutation.
    J Nat Sci Biol Med. 2016,7(2):119-23.
  • Sekimoto Y, Kato M, Shukuya T, Koyama R, Nagaoka T, Takahashi K.
    Bevacizumab-induced chronic interstitial pneumonia during maintenance therapy in non-small cell lung cancer.
    Respirol Case Rep. 2016 ,4(2):e00151.
  • Ebana H, Otsuji M, Mizobuchi T, Kurihara M, Takahashi K, Seyama K.
    Pleural Covering Application for Recurrent Pneumothorax in a Patient with Birt-Hogg-Dub? Syndrome.
    Ann Thorac Cardiovasc Surg.2016, 22(3):189-92.
  • Fukui M, Takamochi K, Matsunaga T, Oh S, Ando K, Suzuki K, Arakawa A, Uekusa T, Suzuki K.
    Risk of the preoperative underestimation of tumour size of lung cancer in patients Hayashida M, Yasuo M, Hanaoka M, Seyama K, Inoue Y, Tatsumi K, Mishima M; Respiratory Failure Research Group of the Ministry of Health, Labour, and Welfare, Japan.
    Reductions in pulmonary function detected in patients with lymphangioleiomyomatosis: An analysis of the Japanese National Research Project on Intractable Diseases database.
    Respir Investig. 2016,54(3):193-200.
  • Ebana H, Otsuji M, Mizobuchi T, Kurihara M, Takahashi K, Seyama K.
    Pleural Covering Application for Recurrent Pneumothorax in a Patient with Birt-Hogg-Dub? Syndrome.
    Ann Thorac Cardiovasc Surg. 2016,22(3):189-92.
  • Sakurai F, Narii N, Tomita K, Togo S, Takahashi K, Machitani M, Tachibana M, Ouchi M, Katagiri N, Urata Y, Fujiwara T, Mizuguchi H.
    Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus.
    Mol Ther Methods Clin Dev. 2016,3:16001.
  • Sawada T, Watanabe M, Fujimura Y, Yagishita S, Shimoyama T, Maeda Y, Kanda S, Yunokawa M, Tamura K, Tamura T, Minami H, Koh Y, Koizumi F.
    Sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells.
    Cancer Sci. 2016,107(3):307-14.
  • Seyama K, Hirai T, Mishima M, Tatsumi K, Nishimura M; Respiratory Failure Research Group of the Japanese Ministry of Health, Labour, and Welfare.
    A nationwide epidemiological survey of alpha1-antitrypsin deficiency in Japan.
    Respir Investig. 2016,54(3):201-6.
  • Yamada K, Ichiki M, Takahashi K, Hisamatsu Y, Takeoka H, Azuma K, Shukuya T, Nishikawa K, Tokito T, Ishii H, Hoshino T.
    A multicenter phase II trial of S-1 combined with bevacizumab after platinum-based chemotherapy in patients with advanced non-squamous non-small cell lung cancer
    Cancer Chemother Pharmacol. 2016,78(3):501-7.
  • Yoshimi K, Oh S, Suzuki K, Kodama Y, Sekiya M, Seyama K, Fukuchi Y.
    Impact of Airflow Limitation on Comorbidities and Postoperative Complications in Patients Undergoing Thoracic Surgery: A Retrospective Observationa
    Ann Thorac Cardiovasc Surg. 2016,22(3):146-52.
  • Hoshika Y, Takahashi F, Togo S, Hashimoto M, Nara T, Kobayashi T, Nurwidya F, Kataoka H, Kurihara M, Kobayashi E, Ebana H, Kikkawa M, Ando K, Nishino K, Hino O, Takahashi K, Seyama K.
    Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dub? syndrome.
    Physiol Rep. 2016,4(21). pii: e13025.
  • Kato M, Sasaki S, Izumi H, Uekusa T, Tominaga S, Takahashi K.
    Development of diffuse alveolar damage after initiation of Nijutsuto.
    Respirol Case Rep. 2016,25;4(6):e00195.
  • Ando K, Nakashita T, Kaneko N, Takahashi K, Motojima S.
    Associations between peripheral blood eosinophil counts in patients with systemic sclerosis and disease severity.
    Springer Plus 2016,5: 1401.
  • Nakashita T, Ando K, Takahashi K, Motojima S.
    Possible effect of abatacept on the progression of interstitial lung disease in rheumatoid arthritis patients.
    Respiratory Investigation. 2016,54(5): 376-379.
  • Comaills V, Kabeche L, Morris R, Buisson R, Yu M, Madden MW, LiCausi JA, Boukhali M, Tajima K, Pan S, Aceto N, Sil S, Zheng Y, Sundaresan T, Yae T, Jordan NV, Miyamoto DT, Ting DT, Ramaswamy S, Haas W, Zou L, Haber DA, Maheswaran S
    Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition
    Cell Rep. 2016,6;17(10):2632-2647
  • McCormack FX, Gupta N, Finlay GR, Young LR, Taveira-DaSilva AM, Glasgow CG, Steagall WK, Johnson SR, Sahn SA, Ryu JH, Strange C, Seyama K, Sullivan EJ, Kotloff RM, Downey GP, Chapman JT, Han MK, D'Armiento JM, Inoue Y, Henske EP, Bissler JJ, Colby TV, Kinder BW, Wikenheiser-Brokamp KA, Brown KK, Cordier JF, Meyer C, Cottin V, Brozek JL, Smith K, Wilson KC, Moss J; ATS/JRS Committee on LymphangioleiomyomatosisOfficial American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines:
    Lymphangioleiomyomatosis Diagnosis and Management.
    Am J Respir Crit Care Med. 2016,15;194(6):748-61
  • Shigematsu, M., T. Koga, A. Ishimori, K. Saeki, Y. Ishii, Y. Taketomi, M. Ohba, A. Jo-Watanabe, T. Okuno, N. Harada, T. Harayama, H. Shindou, J. D. Li, M. Murakami, S. Hoka, and T. Yokomizo.
    Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury. Sci Rep, 2016; 6: 34560.
  • Shigeru Tominaga
    Clinic-based lung cancer screening in Urayasu
    Juntendo Medical Journal 2016;62(6):455-459.
  • Ishimori A, Harada N, Chiba A, Harada S, Matsuno K, Makino F, Ito J, Ohta S, Ono J, Atsuta R, Izuhara K, Takahashi K, Miyake S.
    Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma.
    Allergol Int. 2016 Aug 26.
  • Hishida T, Miyaoka E, Yokoi K, Tsuboi M, Asamura H, Kiura K, Takahashi K, Dosaka-Akita H, Kobayashi H, Date H, Tada H, Okumura M, Yoshino I.
    Lobe-Specific Nodal Dissection for Clinical Stage I and II NSCLC: Japanese Multi-Institutional Retrospective Study Using a Propensity Score Analysis.
    J Thorac Oncol. 2016,11(9):1529-37.
  • Jiang L, Konishi H, Nurwidya F, Takahashi F, Ebinuma H, Fujimura K, Takasu K, Jiang M, Bujo H, Daida H.
    Deletion of smooth muscle cell migration regulator LR11 attenuates the hypoxia- induced pulmonary arterial remodeling with medial thickening in mice.
    Arterioscler Thromb Vasc Biol 2016,36(9):1972-9.
  • Kurihara M, Mizobuchi T, Kataoka H, Sato T, Kumasaka T, Ebana H, Yamanaka S, Endo R, Miyahashira S, Shinya N, Seyama K.
    A Total Pleural Covering for Lymphangioleiomyomatosis Prevents Pneumothorax Recurrence.
    PLoS One. 2016,22;11(9):e0163637
  • Ando K, Fujino N, Mitani K, Ota C, Okada Y, Kondo T, Mizobuchi T, Kurihara M, Suzuki K, Hoshika Y, Ebana H, Kobayashi E, Takahashi K, Kubo H, Seyama K.
    Isolation of individual cellular components from lung tissues of patients with lymphangioleiomyomatosis.
    Am J Physiol Lung Cell Mol Physiol. 2016;310(10):L899-908.
  • Kato M, Shukuya T, Mori K, Kanemaru R, Honma Y, Nanjo Y, Muraki K, Shibayama R, Koyama R, Shimada N, Takahashi F, Takahashi K.
    Cerebral infarction in advanced non-small cell lung cancer: a case control study.
    BMC Cancer. 2016,10;16:203.
  • Okuma HS, Horinouchi H, Kitahara S, Asao T, Sunami K, Goto Y, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Ohe Y.
    Comparison of amrubicin and weekly cisplatin/etoposide/irinotecan in patients with relapsed small-cell lung cancer.
    Clin Lung Cancer 2016 Oct 25.
  • Yuuki Sandhu, Katsutoshi Ando, Hidenori Takekawa, Haruhi Takagi, Michihiro Hirama, Kenji Kido, Kazuhisa Takahashi
    Safety of Bronchoscopy for Patients Undergoing Hemodialysis
    Respiratory Investigation, 2016; 10. 007
  • Shukuya T, Mori K, Amann JM, Bertino EM, Otterson GA, Shields PG, Morita S, Carbone DP.
    Relationship between Overall Survival and Response or Progression-Free Survival in Advanced Non-Small Cell Lung Cancer Patients Treated with Anti-PD-1/PD-L1 Antibodies.
    J Thorac Oncol. 2016,11(11):1927-1939.
  • Takada T, Mikami A, Kitamura N, Seyama K, Inoue Y, Nagai K, Suzuki M, Moriyama H, Akasaka K, Tazawa R, Hirai T, Mishima M, Hayashida M, Hirose M, Sugimoto C, Arai T, Hattori N, Watanabe K, Tamada T, Yoshizawa H, Akazawa K, Tanaka T, Yagi K, Young LR, McCormack FX, Nakata K.
    Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis.
    Ann Am Thorac Soc. 2016,13(11):1912-1922.
  • Asao T, Fujiwara Y, Itahashi K, Kitahara S, Goto Y, Horinouchi H, Kanda S, Nokihara H, Yamamoto N, Ohe Y.
    Sequential use of anaplastic lymphoma kinase inhibitors in Japanese patients with ALK-rearranged non-small-cell lung cancer Sequential use of anaplastic lymphoma kinase inhibitors in Japanese patients with ALK-rearranged non-small-cell lung cancer: A retrospective analysis.
    Clin Lung Cancer 2016 Dec 7
  • Hashimoto M, Asai A, Kawagishi H, Mikawa R, Iwashita Y, Kanayama K, Sugimoto K, Sato T, Maruyama M, Sugimoto M.
    Elimination of p19ARF-expressing cells enhances pulmonary function in mice
    JCI Insight, 2016;1(12):e87732
  • Yamane Y, Shiono A, Ishii Y, Isobe K, Miyauchi E, Kishi K, Nishino M, Sugawara S, Ko R, Koyama N, Yabuki Y, Kobayashi K
    Treatment and outcomes of advanced/recurrent non-small cell lung cancer harboring the EGFR T790M mutation: a retrospective observational study of 141 patients in Japan
    Jpn J Clin Oncol, 2016,46(12): 1135-1142
  • Atsuta R, To Y, Sakamoto S, Mukai I, Kobayashi A, Kinoshita A, Takahashi K.
    Assessing usability of the Adherence Starts with Knowledge 20 (ASK-20) questionnaire for Japanese adults with bronchial asthma receiving inhaled corticosteroids long term.
    Allergol Int. pii: S1323-8930(16)30150-2, 2016.
  • Hayashi T, Kumasaka T, Mitani K, Okada Y, Kondo T, Date H, Chen F, Oto T, Miyoshi S, Shiraishi T, Iwasaki A, Hara K, Saito T, Ando K, Kobayashi E, Gunji-Niitsu Y, Kunogi M, Takahashi K, Yao T, Seyama K.
    Bronchial involvement in advanced stage lymphangioleiomyomatosis: histopathologic and molecular analyses.
    Hum Pathol. 2016,50:34-42.
  • Katsuya Y, Horinouchi H, Asao T, Kitahara S, Goto Y, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Watanabe S, Tsuta K, Ohe Y.
    Expression of programmed death 1 (PD-1) and its ligand (PD-L1) in thymic epithelial tumors: Impact on treatment efficacy and alteration in expression after chemotherapy.
    Lung Cancer 2016; 99: 4-10.
  • Kentaro Suina , Takehito Shukuya, , Ryo Koyama , Tetsuhiko Asao , Yuichiro Honma , Motoyasu Kato , Keiko Muraki , Rina Shibayama , Naoko Shimada , Fumiyuki Takahashi , Shoko Sakuraba , Kazuhisa Takahashi
    Risk factors for serious adverse events due to cytotoxic chemotherapy for advanced non-small cell lung cancer.
    Cancer Treatment and Research Communications 2016;19:106
  • Kodama Y, Kishimoto Y, Muramatsu Y, Tatebe J, Yamamoto Y, Hirota N, Itoigawa Y, Atsuta R, Koike K, Sato T, Aizawa K, Takahashi K, Morita T, Homma S, Seyama K, Ishigami A
    Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome, and bronchial asthma.
    The Clinical Respiratory Journal2016 ISSN 1752-6981