英文論文
JUMP関連
- Kita Y, Baba H, Maeshima H, Nakano Y, Suzuki T, Arai H. Serum amyloid beta protein in young and elderly depression: a pilot study. Psychogeriatrics. 2009 Dec;9(4):180-5.
- Baba K, Baba H, Noguchi I, Arai R, Suzuki T, Mimura M, Arai H. Executive dysfunction in remitted late-life depression: Juntendo University Mood Disorder Projects (JUMP). J Neuropsychiatry Clin Neurosci. 2010, 22(1):70-4.
- Nakano Y, Baba H, Maeshima H, Kitajima A, Sakai Y, Baba K, Suzuki T, Mimura M, Arai H. Executive dysfunction in medicated, remitted state of major depression. J Affect Disord. 2008 Nov;111(1):46-51.
- Baba H, Kubota Y, Suzuki T, Arai H. Seven cases of late-life depression treated with cilostazol-augmented therapy. J Clin Psychopharmacol.Dec;27(6):727-8.2007
- Hatta K, Wolterink G, Van Ree JM: Prolyl-leucyl-glycinamide, thyrotropin-releasing hormone and β-endorphin-(10-16), like antidepressants, antagonize melatonin-induced behavioural changes in rats. Eur J Pharmacology 284: 327-330, 1995
- Kawada Y, Hattori M, Fukuda R, Arai H, Inoue R, Nanko S. No evidence of linkage or association between tyrosine hydroxylase gene and affective disorder. J Affect Disord. 1995 May 17;34(2):89-94.
JUSP関連
- Hanzawa R, Ohnuma T, Nagai Y, Shibata N, Maeshima H, Baba H, Hatano T, Takebayashi Y, Hotta Y, Kitazawa M, Arai H: No association between glutathione-synthesis-related genes and Japanese schizophrenia. Psychiatry Clin Neurosci 2010
- Hotta Y, Ohnuma T, Hanzawa R, Shibata N, Maeshima H, Baba H, Hatano T, Takebayashi Y, Kitazawa M, Higa M, Suzuki T, Arai H: Association study between Disrupted-in-Schizophrenia-1 (DISC1) and Japanese patients with treatment-resistant schizophrenia (TRS). Prog Neuropsychopharmacol Biol Psychiatry: 30; 636-9, 2011
- Ohnuma T, Arai H: Significance of NMDA receptor-related glutamatergic amino acid levels in peripheral blood of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 35: 29-39, 2011
- Hatano T, Ohnuma T, Sakai Y, Shibata N, Maeshima H, Hanzawa R, Suzuki T, Arai H. Plasma alanine levels increase in patients with schizophrenia as their clinical symptoms improve-Results from the Juntendo University Schizophrenia Projects (JUSP). Psychiatry Res 2010; 177: 27-31.
- Higa M, Ohnuma T, Maeshima H, Hatano T, Hanzawa R, Shibata N, Sakai Y, Suzuki T, Arai H. Association analysis between functional polymorphism of the rs4606 SNP in the RGS2 gene and antipsychotic-induced Parkinsonism in Japanese patients with schizophrenia: results from the Juntendo University Schizophrenia Projects (JUSP). Neurosci Lett 2010; 469: 55-9.
- Nagai Y, Ohnuma T, Karibe J, Shibata N, Maeshima H, Baba H, Hatano T, Hanzawa R, Arai H. No genetic association between the SLC1A2 gene and Japanese patients with schizophrenia. Neurosci Lett 2009; 463: 223-7.
- Nozawa M, Ohnuma T, Matsubara Y, Sakai Y, Hatano T, Hanzawa R, Shibata N, Arai H. The Relationship Between the Response of Clinical Symptoms and Plasma Olanzapine Concentration, Based on Pharmacogenetics: Juntendo University Schizophrenia Projects (JUSP). Ther Drug Monit 2008; 30: 35-40.
- Ohi K, Hashimoto R, Yasuda Y, Yoshida T, Takahashi H, Iike N, Fukumoto M, Takamura H, Iwase M, Kamino K, Ishii R, Kazui H, Sekiyama R, Kitamura Y, Azechi M, Ikezawa K, Kurimoto R, Kamagata E, Tanimukai H, Tagami S, Morihara T, Ogasawara M, Okochi M, Tokunaga H, Numata S, Ikeda M, Ohnuma T, Ueno SI, Fukunaga T, Tanaka T, Kudo T, Arai H, Ohmori T, Iwata N, Ozaki N, Takeda M. Association study of the G72 gene with schizophrenia in a Japanese population: A multicenter study. Schizophr Res 2009.
- Ohnuma T, Sakai Y, Maeshima H, Hatano T, Hanzawa R, Abe S, Kida S, Shibata N, Suzuki T, Arai H. Changes in plasma glycine, l-serine, and d-serine levels in patients with schizophrenia as their clinical symptoms improve: Results from the Juntendo University Schizophrenia Projects (JUSP). Prog Neuropsychopharmacol Biol Psychiatry 2008; 32: 1905-12.
- Ohnuma T, Shibata N, Baba H, Ohi K, Yasuda Y, Nakamura Y, Okochi T, Naitoh H, Hashimoto R, Iwata N, Ozaki N, Takeda M, Arai H. No association between DAO and schizophrenia in a Japanese patient population: a multicenter replication study. Schizophr Res 2010; 118: 300-2.
- Ohnuma T, Shibata N, Maeshima H, Baba H, Hatano T, Hanzawa R, Arai H. Association analysis of glycine- and serine-related genes in a Japanese population of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2009; 33: 511-8.
- Higashi M, Higashi S, Ohnuma T, Shibata N, Sakai Y, Arai H. Genetic analysis of the TrkB gene and schizophrenia in the Japanese population: Juntendo University Schizophrenia Projects (JUSP) Neurosci Lett. 2007
- Maeshima H, Ohnuma T, Sakai Y, Shibata N, Baba H, Ihara H, Higashi M, Ohkubo T, Nozawa E, Abe S, Ichikawa A, Nakano Y, Utsumi Y, Suzuki T, Arai H. Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia-Juntendo University Schizophrenia Projects (JUSP). Prog Neuropsychophamacol & Biol Psychiatry. 31(7) 1410-8.2007
- Inami R, Kirino E, Inoue R, Suzuki T, Arai H,: Nicotine Effects on Mismatch Negativity in Nonsmoking Schizophrenic Patients. Neuropsychobiology 56 (2-3):64-72, 2007
- Nakamura K, Koyama Y, Takahashi K, Tsurui H, Yan X , Ohtsuji M, Qing S-L, Sugawara Y, Sawabe K, Ohashi A, Ohnuma T, Arai H, Nishimura H, Hasegawa H,and Hirose S, Requirement of Trypotophan Hydroxylase During Development for Maturation of Sensorimotor Gating. J. Mol. Biol. 363,345-354. 2006
- Kawashima R, Ohnuma T, Shibata N, Arai H. No genetic association between postsynaptic density-95 gene polymorphisms and schizophrenia. Neurosci Lett. 400(1-2):168-71. 2006
- Shibata N, Ohnuma T, Higashi S, Higashi M, Usui C, Ohkubo T, Watanabe T, Kitajima A, Ueki A, Nagao M, Arai H. Genetic association between Notch4 polymorphisms and Japanese schizophrenics. Psychiatr Genet. Apr;16(2):77-9.2006
- Japanese Schizophrenia Sib-Pair Linkage Group (Arai H, Ohnuma T incl.). Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p Am J Hum Genet. Dec;77(6):937-44. 2005
- Minami Y, Kirino E: Schizophrenic Patients are Impaired in Memory Reinstatement Underlying Mismatch Negativity System. Clin Neurophysiol 116 (1): 120-128, 2005
- Inami R, Kirino E, Inoue R, Arai H. Transdermal nicotine administration enhances automatic auditory processing reflected by mismatch negativity. Pharmacology, Biochemistry and Behavior 80:453-461 2005
- Ohnuma T, Suzuki T, Arai H. Hypothesis: minimal changes in neural transmission in schizophrenia: decreased glutamatergic and GABAergic functions in the prefrontal cortex.Progress in Neuro-psychopharmacology & Biological Psychiatry29:889-894 2005
- Baba H, Suzuki T, Arai H and P C.Emson. Expression of nNOS and soluble guanylate cyclase in schizophrenic brain. NeuroReport.15(4):677-680 2004
- Ohnuma T, Shibata N, Matsubara Y and Arai H,: Haloperidol plasma concentration in Japanese psychiatric subjects with gene duplication of CYP2D6. Br J Clin Pharmacol. 56:315-320 2003
- Ohnuma T, Kato H, Arai H, P J.Mckenna, P C. Emson. Expression of Fyn, a non-receptor tyrosine kinase in prefrontal cortex from patients with schizophrenia and its correlation with clinical onset. Molecular Brain Research.112:90-94 2003
- Ohnuma T, Shibata N, Matsubara Y, Sato S, Yamashina M, and Arai H. No genetic association between polymorphisms in the Fyn kinase gene and age of schizophrenic onset Neurosci Lett, 343:70-72 2003
- Matsubara Y, Ohnuma T, Shibata N, Takahashi T, and Arai H. Plasma Concentration of Risperidone Showed a Correlation with Daily Dose, but not with Age nor Cytochrome P-450 2D6 Gene Polymorphisms in Japanese Schizophrenics. Psychogeriatrics, 2(4): 284-288 2002
- Takahashi T, Emson PC, Arai H. Region-specific and age-related decrease of parval bumin gene expression in the prefrontal cortex of elderly patients with schizophrenia. Psychogeriatrics, 2:26-34 2002
- Shimada H, Ohnuma T, Emson PC, Arai H::Effect of Aging on Gene Expression of Metabotropic Glutamate Receptor 5 and Glutamate Transporter-1 in the Prefrontal Cortex of Schizophrenics. Psychogeriatrics, 1:50-55,2001
- Kirino E, Belger A, Goldman-Rakic PS, McCarthy G: Prefrontal Activation to Infrequent Visual Target and Novel Stimuli: An Event-Related fMRI study. J Neurosci 20 (17): 6616-6618, 2000
- Niizato K, Iritani S, Ikeda K, Arai H. Astroglial function of schizophrenic brain: a study using lobotomized brain, Neuroreport, 12:1457-1460, 2000
- Ohnuma T, Kato H, Arai H, Faull RL.M., Mckenna PJ, Emson PC. Gene expression of PSD95 in prefrontal cortex and hippocampus in schizophrenia. Neuroreport, 11:3133- 3137, 2000
- Ohnuma T, Tessler S, Arai H, Faull RL, McKenna PJ, Emson PC. Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus. Brain research 85:24-31 2000.
- Ichiki M, Kunugi H, Takei N, Murray RM, Baba H, Arai H, Oshima I, Okagami K. Intra-uterine physical growth in schizophrenia evidence confirming excess of premature birth. Psychological Medicine. Psychological Medicine. 30: 597-604, 2000
- Ohnuma T, Augood SJ, Arai H, McKenna PJ, Emson PC. Measurement of GABA nergic parameters in the prefrontal cortex in schizophrenia: Focus on GABA content, GABA (A) receptor alpha- 1 subunit messenger RNA and human GABA transporter-1 (HGAT- 1) messenger RNA expression. Neuroscience. 93:441-448, 1999
- Shibata N, Ohnuma T, Baba H, Shimada T, Takahashi T, Arai H. Genetic association between cytochrome P-450 2D6 gene polymorphism and plasma concentration of haloperidol in Japanese schizophrenics. Psychiatric Geneti. 9:145-148, 1999
- Ohnuma T, Augood S J, Arai H, McKenna P J, Emson P C. Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Molecular Brain Research. 56: 207-217, 1998
- Ohnuma T, Kimura M, Takahashi T, Iwamoto N, Arai H. A magnetic resonance imaging study in first-episode disorganized-type patients with schizophrenia. Pshychiatry and Clin Neurosci.51:9-15,1997
- Nagaoka S, Iwamoto N, Arai H. First-episode neuroleptics-free schizophrenics: concentrations of monoamines and their metabolites in plasma and their correlations with clinical responses to haloperidol treatment. Biol Psychiat.41:857-864,1997
- Hatta K, Yamamoto T, Hori T, et al: Differential inhibition of magnesium- and glutamate-induced [3H]N-(1-[2-thienyl]cyclohexyl)-3,4-piperidine ([3H]TCP) binding by competitive N-methyl-D-aspartate antagonists. Mol Neuropharmacol 1: 173-177, 1992
- Hatta K, Yamamoto T, Hori T, Okuwa M, Moroji T: Effects of glycine antagonists on Mg2+- and glycine-induced [3H]N-(1-[2-thienyl]cyclohexyl)-3,4-piperidine binding. Neurosci Lett 138: 53-55, 1992
- Hatta K, Yamamoto T, Hori T, et al: 3-((+)2-Carboxypiperazine-4-yl)propyl-1-phosphonic acid (CPP) more potently antagonizes the high-affinity Mg2+ binding site on the N-methyl-D-aspartate/phencyclidine receptor ion channel complex than the L-glutamate recognition site. Neurosci Lett 124: 229-231, 1991
- Hori T, Yamamoto T, Hatta K, et al: Modulation of Mg2+-dependent [3H]TCP binding by L-glutamate, glycine, and guanine nucleotides in rat cerebral cortex. Synapse 8: 13-21, 1991
- Hori T, Yamamoto T, Hatta K, et al: Biphasic effects of magnesium on the [3H]TCP binding in the rat cerebral cortex. Neurosci Lett 119: 9-11, 1990
JBEP関連
- Ito M, Seki T, Liu J, Nakamura K, Namba T, Matsubara Y, Suzuki T, Arai H. Effects of repeated electroconvulsive seizure on cell proliferation in the rat hippocampus. Synapse. Nov;64(11):814-21. 2010
- Tanimura A, Liu J, Namba T, Seki T, Matsubara Y, Itoh M, Suzuki T, Arai H. Prenatal phencyclidine exposure alters hippocampal cell proliferation in offspring rats. Synapse. Sep;63(9):729-36. 2009
- Liu J, Suzuki T, Seki T, Namba T, Tanimura A, Arai H. Effects of repeated phencyclidine administration on adult hippocampal neurogenesis in the rat. Synapse. Apr 4;60(1):56-68 2006
- Abe S, Suzuki T, Endo K, Hori T, Arai H, Effects of single and repeated phencyclidine administration on [3H]flunitrazepam binding in rat brain. Progress in Neuro-psychopharmacology & Biological Psychiatry 29 (2005)133-140 2005
- Yamaguchi M, Suzuki T, Seki T, Namba T, Liu J, Arai H, Hori T, Shiga T. Decreased cell proliferation in the dentate gyrus of rats after repeated administration of cocaine. Synapse: 90-93 2005
- Yamaguchi M, Suzuki T, Seki T, Nanba T, Juan R, Arai H, Hori T, And Asada T, Repectitive Cocaine Administration Decreases Neurogenesis in Adult Rat Hippocampus. Ann. N. Y. Acad. Sci. 1025: 351-362 2004
- Suzuki T, Ohnuma T, Shozo , Abe M, Yamaguchi, Hori T, and Arai H. Glutamaterogic and GABAergic dysfunctions in animal models of schizophrenia-comparison of data with those from schizophrenia. Current Topics in Pharmacology 8(1): 92-120 2004
- Yamaguchi M, Suzuki T, Abe S, Hori T, Kurita H, Asada T, Okado N, Arai H. Repeated cocaine administration differentially affects NMDA receptor subunit (NR1, NR2A-C) mRNAs in rat brain. Synapse, 46:157-169.2002
JUAP関連
- Hirano S, Shinotoh H, Shimada H, Aotsuka A, Tanaka N, Ota T, Sato K, Ito H, Kuwabara S, Fukushi K, Irie T, Suhara T. Cholinergic imaging in corticobasal syndrome, progressive supranuclear palsy and frontotemporal dementia. Brain. 133:2058-68, 2010
- Ota T, Shinotoh H, Fukushi K, Kikuchi T, Sato K, Tanaka N, Shimada H, Hirano S, Miyoshi M, Arai H, Suhara T, Irie T. Estimation of plasma IC50 of donepezil for cerebral acetylcholinesterase inhibition in patients with Alzheimer disease using positron emission tomography. Clin Neuropharmacol. Mar-Apr;33(2):74-8. 2010
- Kuerban B, Shibata N, Komatsu M, Ohnuma T, Arai H. Genetic Association between PLTP Gene Polymorphisms and Alzheimer's Disease in a Japanese Population. Dement Geriatr Cogn Disord. 12;30(1):78-82, 2010
- Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, Riemenschneider M, Owen M, Harold D, Hollingworth P, Cellini E, Sorbi S, Nacmias B, Takeda M, Pericak-Vance MA, Haines JL, Younkin S, Williams J, van Broeckhoven C, Farrer LA, St George-Hyslop PH, Mayeux R; for the Genetic and Environmental Risk in Alzheimer Disease 1 Consortium. Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease. Arch Neurol. 68 (1):99-106, 2011
- Komatsu M, Shibata N, Kuerban B, Ohnuma T, Baba H, Arai H. Genetic association between clusterin polymorphisms and Alzheimer's disease in a Japanese population. Psychogeriatrics. 11(1):14-8, 2011
- Murayama N, Iseki E, Fujishiro H, Yamamoto R, Ota K, Nagashima K, Arai H, Sato K: Detection of early amnestic mild cognitive impairment without significantly objective memory impairment; a case controlled study. Psychogeriatrics 10: 62-68, 2010
- Asaoka T, Tsuchiya K, Fujishiro H, Arai T, Hasegawa M, Akiyama H, Iseki E, Oda T, Onaya M, Tominaga I: Argyrophilic grain disease with delusions and hallucinations: a pathological study. Psychogeriatrics 10: 69-76, 2010
- Fujishiro H, Iseki E, Murayama N, Yamamoto R, Kasanuki K, Higashi S, Suzuki M, Arai H, Sato K: Diffuse occipital hypometabolism on 18F-FDG PET scans in patients with idiopathic REM sleep behavior disorder: prodromal dementia with Lewy bodies? Psychogeriatrcns 10: 144-152, 2010
- Fujishiro H, Iseki E, Higashi S, Kasanuki K, Murayama N,Togo T, Katuse O, Uchikado H, Aoki N, Kosaka K, Arai H, Sato K: Distribution of cerebral amyloid deposition and ita relevance to clinical phenptype in Lewy body disease. Neurosci Lett 486: 19-23, 2010
- Higashi S, Iseki E, Minegishi M, Togo T, Kabuta T, Wada K: GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation. J Neurochem 115: 423-437, 2010
- Aoki N, Tsuchiya K, Togo T, Kobayashi Z, Uchikado H, Katuse O, Suzuki K, Fujishiro H, Arai H, Iseki E, Anno M, Kosaka K, Akiyama H, Hirayasu Y: Gray matter lesions in Nasu-Hakola disease: a report on three autopsy cases. Neuropathology 31: 135-145, 2011
- Higashi S, Moore DJ, Yamamoto R, Minegishi M, Sato K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Hino H, Kosaka K, Emson PC, Wada K, Dawson VL, Dawson TM, Arai H, Iseki E: Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies. J Neuropathol Exp Neurology 70: 264-280, 2011
- Utumi Y, Iseki E, Murayama N, Nozawa M, Kumagai R, Mattsubara Y, Ichimiya Y, Arai H: Effect of Rikkunshi-to on appetite loss found in elderly dementia patients: a preliminaru study. Psychogeriatrics 11: 34-39, 2011
- Iseki E, Murayama N, Yamamoto R, Fujishiro H, Suzuki M, Kawano M, Miki S, Sato K: Construction of a 18F-FDG PET normative database of Japanese healthy elderly subjects and its application to demented and mild cognitive impairment patients. Int J Geriatr Psychiatry 25: 352-361, 2010
- Shibata N, Kuerban B, Komatsu M, Ohnuma T, Baba H, Arai H. Genetic Association Between CALHM1, 2, and 3 Polymorphisms and Alzheimer's Disease in a Japanese Population. Journal of Alzheimer’s Disease 20: 2:417-21, 2010
- Shibata N, Ohnuma T, Baba H, Arai H. Genetic Association Analysis between TDP-43 Polymorphisms and Alzheimer's Disease in a Japanese Population. Dement Geriatr Cogn Disord. 28:325-329, 2009
- Shibata N, Shimazaki H, Sano N, Kawasaki S, Arai H. Psychiatric and psychological outcomes of Japanese living donors following liver transplantation. Psychiatry Clin Neurosci. 63, 583-585, 2009
- Shibata N, Arai H, Alzheimer's disease and mortality in Japan. Psychogeriatrics 9, 1-3, 2009
- Fujishiro H, Uchikado H, Arai T, Hasegawa M, Akiyama H, Yokota O, Tsuchiya K, Togo T, Iseki E, Hirayasu Y: Accumulation of phosphorylated TDP-43 in brains of patients with argyrophilic grain disease. Acta Neuropathol 117: 214-223, 2009
- Frigerio R, Fujishiro H, Maraganore DM, Klos KJ, DelleDonne A, Heckman MG, Crook JE, Josephs KA, Parisi JE, Boeve BF, Dickson DW, Ahlskog JE. Comparison of risk factor profiles in incidental Lewy body disease and Parkinson disease. Arch Neurol. 66:1114-9, 2009
- Dickson DW, Fujishiro H, Orr C, DelleDonne A, Josephs KA, Frigerio R, Burnett M, Parisi JE, Klos KJ, Ahlskog JE. Neuropathology of non-motor features of Parkinson disease. Parkinsonism Relat Disord. Suppl 3:S1-5, 2009
- Dickson DW, Uchikado H, Fujishiro H, Tsuboi Y. Evidence in favor of Braak staging of Parkinson's disease. Mov Disord 25(S1):S78-S82, 2010
- Yamamoto R, Iseki E, Murayama N, Minegishi M, Higashi S, Hino H, Fujisawa K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Kosaka K, Yoshida M, Hashizume Y, Arai H: Neuropathological investigation of regions responsible for semantic aphasia in frontotemporal lobar degeneration. Dement Geriatr Cogn Disord 27: 214-223, 2009
- Nozawa M, Ichimiya Y, Nozawa E, Utumi Y, Sugiyama H, Murayama N, Iseki E, Arai H: Clinical effects of high oral dose of donepezil for patients with Alzheimer’s disease in Japan. Psychogeriatrics 9: 50-55, 2009
- Murayama N, Iseki E, Endo T, Nagashima K, Yamamoto R, Ichimiya Y, Arai H, Sato K: Risk factors for delusion of theft in patients with Alzheimer's disease showing mild dementia in Japan. Aging & Mental Health 13: 563-568, 2009
- Higashi S, Moore DJ, Yamamoto R, Minegishi M, Sato K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Hino H, Kosaka K, Emson PC, Wada K, Dawson VL, Dawson TM, Arai H, Iseki E: Abnormal localization of LRRK2 to the endosomal-lysosomal compartment in Lewy body disease. J Neuropathol Exp Neurology 68: 994-1005, 2009
- N. Shibata, T. Ohnuma, H. Baba and H. Arai. No Genetic Association between Polymorphisms of Heme Oxygenase 1 and 2 and Alzheimer's Disease in a Japanese Population. Dement Geriatr Cogn Disord 27; 273-7. 2009
- N. Shibata, T. Ohnuma, H. Baba, S. Higashi, K. Nishioka and H. Arai. Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population. Dement Geriatr Cogn Disord 26; 161-4. 2008
- N. Shibata, T. Ohnuma, S. Higashi, M. Higashi, C. Usui, T. Ohkubo, T. Watanabe, R. Kawashima, A. Kitajima, A. Ueki, M. Nagao and H. Arai. Genetic association between Notch4 polymorphisms and Alzheimer's disease in the Japanese population. J Gerontol A Biol Sci Med Sci 62; 350-1. 2007
- Matsuda H, Mizumura S, Nagao T, Ota T, Iizuka T, Nemoto K, Takamura N, Arai H, Homma A. Automated Discrimination Between Very Early Alzheimer disease and Controls Using an Easy Z-Score Imaging system for Multicenter Brain Perfusion Single-Photon Emission Tomography. AJNR Am J Neuroradiol.28:731-736 2007
- Yamamoto R, Iseki E, Murayama N, Minegishi M, Marui W, Togo T, Katsuse O, kosaka K, Kato M, Iwatsubo T, Arai H. Correlation in Lewy pathology between the claustrum snd visual areas in brains of dementia with Lewy bodies. Neurosci Lett. 415, 219-224 2007
- Higashi S, Iseki E, Yamamoto R, Minegishi M, Hino H, Fijisawa K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Kosaka K, Arai H. Appearance pattern of TDP-43 in Japanese frontotemporal lobar degeneration with ubiquitin-positive inclusions. Neurosci Lett 419: 213-218, 2007
- Higashi S, Iseki E, Yamamoto R, Minegishi M, Hino H, Fujisawa K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Kosaka K, Arai H. Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies. Brain Res 1184: 284-294, 2007
- Oshima K, Akiyama H, Tsuchiya K, Kondo H, Haga C, Shimomura Y, Iseki E, Uchikado H, Kato M, Niizato K, Arai H. Relative paucity of tau accumulation in the small areas with abundant Aβ42-positive capillary amyloid angiopathy within a given cortical region in the brain of patients with Alzheimer pathology. Acta Neuropathol.111:510-518 2006
- Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC. Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain. J Neurochem. 100(2):368-81. 2006
- Arai H, Takano M, Miyakawa K, Ota T, Takahashi T, Asaka H, Kawaguchi T.A quantitative near-infrared spectroscopy study: A decrease in cerebral hemoglobin oxygenation in Alzheimer's disease and mild cognitive impairment. Brain Cogn. 61, 189-194 2006
- Usui C, Shibata N, Ohnuma T, Higashi S, Ohkubo T, Ueki A, Nagao M, Arai H. No Genetic Association between the Myeloperoxidase Gene -463 Polymorphism and Estrogen Receptor-alpha Gene Polymorphisms and Japanese Sporadic Alzheimer's Disease. Dement Geriatr Cogn Disord. Feb 10;21(5-6):296-299 2006
- Shibata N, Ohnuma T, Higashi S, Higashi M, Usui C, Ohkubo T, Watanabe T, Kitajima A, Ueki A, Nagao M, Arai H. Genetic association between USF1 and USF2 Gene polymorphisms and Japanese Alzheimer's Disease. Journal of Gerontology61(7)660-662 2006
- Iseki E, Yamamoto R, Murayama N, Minegishi M, Togo T, Katsuse O, Kosaka K, Akiyama H, Tsuchiya K, de Silva R, Lees A, Arai H: Immunohistochemical investigation of neurofibrillary tangles and their tau isoforms in brains of limbic neurofibrillary tangle dementia. Neurosci Lett 405: 29-33, 2006
- Yamamoto R, Iseki E, Murayama N, Minegishi M, Marui W, Togo T, Katsuse O, Kato M, Iwatsubo T, Kosaka K, Arai H. Investigation of Lewy pathology in the visual pathway of brains of dementia with Lewy bodies. J Neurol Sci 246: 95-101, 2006
- Yamamoto R Iseki E Marui W, Togo T, Katsuse O Kato M, Isosima D Akatsu H Kosaka K, and Arai H. Non‐uniformity in the regional pattern of Lewy pathology in brains of dementia with Lewy body. Neuropathology25:188-194 2005
- Iseki E, Marui W, Yamamoto R, Togo T, Katsuse O, Kato M, Iwatsubo T, Kosaka K, Arai H. The nigro-striatal and nigro-amygdaloid pathways undergo differentdegeneration processes in brains of dementia with Lewy bodies. Neuroscience Letters 380 (2005) 161-165 2005.
- Ohkubo T, Shibata N, Ohnuma T, Higashi S, Usui C, Ueki A, Nagao M, Arai H. No genetic association between ATP binding cassette proteins and Japanese sporadic Alzheimer's disease. Dement Geriatr Cogn Disord. 20(2-3):95-8. 2005
- Shibata N, Ohnuma T, Higashi S, Usui C, Ohkubo T, Kitajima A, Ueki Akira, Nagao M, Arai H, Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease Neurobiology of Aging 26(2005)1011-1014 2005
- Shibata N, Ohnuma T, Higashi S, Higashi M, Usui C, Ohkubo T, Watanabe T, Kawashima R, Kitajima A, Ueki A, Nagao M, Arai H. No genetic association between PCSK9 polymorphisms and Alzheimer's disease and plasma cholesterol level in Japanese patients.Psychiatr Genet. Dec;15(4):239.2005
- Takano M, Arai H. Gender difference and caregivers' burden in early-onset Alzheimer's disease.Psychogeriatrics.5:73-77 2005
- Watanabe T, Ohnuma T, Shibata N, Ohtsuka M, Ueki A, Nagao M, Arai H. No genetic association between Fyn kinase gene polymorphisms (-93A⁄G, IVS10+37T⁄C and Ex12+894T⁄G) and Japanese sporadic Alzheimer's disease. Neurosci Lett. 360(1-2):109-111 2004
- Ota T, Shinotoh H, Fukushi K, Nagatsuka S, Namba H, Iyo M, Aotsuka A, Tanaka N, Sato K, Shiraishi T, Tanada S, Arai H and Irie T. A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: Comparison with [123I]IMP SPECT. Nuclear Medicine18(3)187-193 2004
- Shibata N, Ohnuma T, Takahashi T, Matsubara Y, Ueki A, Nagao M, Arai H.No genetic association between tumour necrosis factor receptor II 196R polymorphism and Japanese sporadic Alzheimer's disease. Psychiatr Genet14(1):53-55 2004
- Oshima K, Tsuchiya I, Arai T, Akiyama H, Iritani S, Niizato K, Ikeda K, Arai H,. Atypical "late-onset dementia" characterized by limbic degeneration with coiled bodies and argyrophilic threads. Clin Neuropathol 22(6):296-303 2003
- Higashi H, Ohnuma T, Shibata N, Ishizuka T, Higashi M, Ohtuka E, Ueki A, Nagao M,Arai H. Association of transforming growth factor-β1 gene polymorphisms in Japanese sporadic Alzheimer's disease. Alzheimer's reports,5:21-24,2002
- Shibata N, Ohnuma T, Takahashi T, Baba H, Ishizuka T, Ohtsuka M, Ueki A, Nagao M,Arai H. Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases. Am J Med Genet, 114:436-439, 2002
- Shibata N, Ohnuma T, Takahashi T, Baba H, Ishizuka T, Ohtsuka M, Ueki A, Nagao M,and Arai H. Effect of IL-6 Polimorphism on Risk of Alzheimer Disease:Genotype-Phenotype Association Study in Japanese Cases. Neuropsychiatric Genetics 114:436-439 2002
- Shibata N, Ohnuma T, Takahashi T, Baba H, Ishizuka T, Ohtsuka M, Ueki A, Nagao M,Arai H. The effect of IL4 +33C⁄T polymorphism on risk of Japanese sporadic Alzheimer's disease. Neurosci Lett, 323:161-163.2002
- Ueda Y, Matsubara H, Shinomiya S, and Arai H. Frontal Theta Rhythm: Evalution of its Clinical Electrophysiological Significance with a View Point of Aging Psychogeriatrics, 2(4): 269-274 2002
- Ishizuka T,Baba H, Higashi H, Arai H. Circulating natural killer cell activity and cytokine production in Alzheimer's disease. Alzheimer's Reports, 4:81-85, 2001
- Arai H, Tsubaki H, Mitsuyama Y, Fujimoto N, Urata Y, Homma A. Early onset Alzheimer type dementia more rapidly deteriorates than late onset type: A follow-up study on MMSE scores in Japanese patients. Psychogeriatrics, 1:303-308, 2001
- Maruyama H, Toji H, Harrington CR, Sasaki K, Izuka Y, Ohnuma T, Arai H, Yasuda M, Tanaka C, Emson PC, Nakamura S, Kawakami H. Lack of an association of estrogen reseptor αgene polymorphisms and transcriptional activity with Alzheimer's Disease. Arch Neurol. 57:236-240, 2000
- Shibata N, Ohnuma T, Takahasi T, Ohtsuka E, Ueki A, Nagao M, Arai H. No genetic association between alpha-2 macroglobulin I1000V polymorphism and Japanese sporadic Alzheimer's disease. Neurosci Lett, 290:154-156, 2000
- Kimura M, Asada T, Uno M, Machida N, Kasuya K, Taniguchi Y, Fujita T, Nishiyama E, Iwamoto N, Arai H. Assessment of cerebrospinal fluid levels of serum amyloid P component in patients with Alzheimer's disease. Neurosci Lett. 273:137-139, 1999
- Shibata N, Ohnuma T, Takahashi T, Ohtsuka E, Ueki A, Arai H. Genetic association between alpha-2 macroglobulin and Japanese sporadic Alzheimer's disease. Neurosci Lett. 271: 132-134, 1999
- Kosaka K, Iseki E, Arai H. Recent advances in dementia research in Japan: Alzheimer- type dementia. Pshychiat Clin Neurosci. 53: 1-10,1999
- Iwamoto N, Nishiyama E, Arai H. Distribution of amyloid deposits in the cerebral white matter of the Alzheimer's disease brain: relation to blood vessels. Acta Neuropathol. 93:334-340,1997
- Nishiyama E, Iwamoto N, Ohwada J, Arai H. Distribution of apolipoprotein E in senile plaques in brains with Alzheimer's disease: investigation with the confocal laser microscope. Brain Res. 750:20-24,1997
- Nishiyama E, Iwamoto N, Kimura M, Arai H. Serum amyloid P component level in Alzheimer's disease. Dementia. 7:256-259, 1996
- Iwamoto N, Nishiyama E, Ohwada J, Noguchi I, Kimura M, Arai H. Amyloid P component immunoreactivity in brains of Alzheimer-type dementia is reduced by formic acid pretreatment on tissue sections. Neuropathology. 15:64-66,1995
- Ohwada J, Nishiyama E, Iwamoto N, Arai H. An immunohistochemical study of Alzheimer neurofibrillary tangles using confocal laser scan microscopy. Neuropathology.15:64-66, 1995
- Nagaoka S, Arai H, Iwamoto N, Ohwada J, Ichimiya Y, Nakamura M, Inoue R. A juvenile case of frontotemporal dementia: Neurochemical and neuropathological investigations. Prog Neuropsychopharmacol & Biol Psychiat. 19:1251-1261,1995
- Minami M, Kimura M, Iwamoto N, Arai H. Endotheline-1-like immunoreactivity in cerebral cortex of Alzheimer-type dementia. Prog Neuropsychopharmacol & Biol Psychiat. 19:509-513,1995
- Minami M, Arai H, Takahashi T, Kimura M, Noguchi I, Suzuki T, Inoue R. A preliminary study of plasma concentrations of bifemelane, indeloxazine and propento fyline in aged patients with organic brain disorders. Prog Neuropsychopharmacol & Biol Psychiat. 19:59-64,1995
- Kimura M, Arai H, Takahashi T, Iwamoto N. Demonstration of CRP immunoreactivity in brains of Alzheimer's disease: immunohistochemical study using formic acid pretreatment of tissue sections. J Neurol.241:170-174, 1994
- Iwamoto N, Nishiyama E, Ohwada J, Arai H. Amyloid-P-component-like immuno-reactivity in β/A4-immunoreactive deposits in Alzheimer-type dementia brains. Neurosci Lett. 177:23-26. 1994
- Nishiyama E, Ohwada J, Iwamoto N, Arai H. Selective loss of calbindin D-28-immunoreactive neurons in the cortical layer II in brains of Alzheimer's disease:a morphometoric study. Neurosci Lett. 163:223-226 1993
- Arai H, Ichimiya Y, Kosaka K, Moroji T, Iizuka R. Neurotransmitter changes in early-and late-onset Alzheimer-type dementia. Prog Neuropsychopharmacol & Biol Psychiat. 16:883-890, 1992
- Noguchi I, Arai H, Iizuka R. A disorganized increase of galanin-like immunoractivity in cerebral cortex of Alzheimer-type dementia brains.J Neural Transm. 83:171-178, 1991
- Minami M, Makino Y, Arai H, Iizuka R. A study on postmortem stability of vasopressin messenger RNA in rat brain compared with those in total RNA and ribosomal RNA. J Neural Transm. 4:285-292, 1991
- Arai H, Noguchi I, Makino Y, Kosaka K, Heizmann CW, Iizuka R. Parvalbumin-immunoreactive neurons in the cortex in Pick's disease. J Neurol. 238:200-202. 1991
- Arai H, Sagi N, Noguchi I, Haga S, Ishii T, Makino Y, Kosaka K. An immuno-histochemical study of β- protein in Alzheimer-type dementia brains. J Neurol. 236:214-217, 1989
- Arai H, Noguchi I, Sagi N, Moroji T, Iizuka R. A study of non-isotopic in situ hybridization histochemistry on postmortem changes in vasopressin mRNA in rat brain. Neurosci Lett. 103:127-132,1989
- Emson PC, Arai H, Agrawall S, Christodoulou C, Gait MJ. Nonradioactive methods of in situ hybridization: visualization of neuroendocrine mRNA. Methods in Enzymology. 168:753-761, 1988
- Arai H, Emson PC, Agrawall S, Christodoulou C, Gait MJ. In situ hybridization histochemistry: localization of vasopressin mRNA in rat brain using a biotinylated oligonucleotide probe. Mol Brain Res. 4:53-70, 1988
- Arai H, Emson PC, Carrasco LH. Huntington's disease: Changes in tachykinin content in postmortem brains. Ann Neurol. 22:587-594, 1987
- Arai H, Emson PC, Mountjoy CH, Carrasco LH, Heinzmann CW. Loss of parv-albumin neurons from cortex in Alzheimer-type dementia. Brain Res. 418:164-169, 1987
- Sawada M, Hirata Y, Arai H, Iizuka R, Nagatsu T. Tyrosine hydroxylase, trypto-phan hydroxylase, biopterin and neopterin in the patients with senile dementia of Alzheimer-type. J Neurochem. 48:760-764, 1987
- Emson PC, Arai H. Functional morphology during normal aging and pathological aging with emphasis on peptidergic transmission. NATO ASI Series. 119:17-25,1987
- Arai H, Sirinathsinghji DJS, Emson PC. Depletion in substance P- and neurokininA-like immunoreactivity in substantia nigra after ibotenate-induced lesions of striatum. Neurosci Res. 5:167-171, 1987
- Ichimiya Y, Arai H, Kosaka K, Iizuka R. Morphological and biochemical changes in the cholinergic and monoaminergic systems in Alzheimer-type dementia. Acta Neuropathol(Berl). 70:112-116, 1986
- Sasaki H, Muramoto O, Kanazawa I, Arai H, Kosaka K, Iizuka R. Regional distri-bution of amino acid transmitters in postmortem brains of presenile and senile dementia of Alzheimer-type. Ann Neurol. 19:263-269, 1986
- Arai H, Moroji T, Kosaka K, Iizuka R. Extrapyramidal distribution ofα-melano-cyte stimulating hormone(α-MSH)-like immunoreactivity in postmortem brains from normal subjects and Alzheimer-type dementia patients. Brain Res. 317:305-310, 1986
- Arai H, Emson PC. Regional distribution of neuropeptide K and other tachykinins (neurokinin A, neurokinin B and substance P ) in rat central nervous system. Brain Res. 399: 240-249, 1986
- Ichimiya Y, Kobayashi K, Arai H, Kosaka K. A computed tomography study of Alzheimer's disease by regional volumetric and parenchymal density measurements. J Neurol. 233:164-167, 1986
- Kosaka K, Arai H, Ikeda K. Familial presenile dementia with CJD-like lesions preliminary results. Clin Neuropathol. 4:149-155,1985
- Arai H, Kobayashi K, Ichimiya Y, Kosaka K, Iizuka R. Free amino acids in post-mortem cerebral cortices from patients with Alzheimer-type dementia. Neurosci Res. 2:486-490, 1985
- Arai H, Kosaka K, Iizuka R. Changes of biogenic amines and their metabolites in postmortem brains from patients with Alzheimer-type dementia. J Neurochem. 43:388-393, 1984
- Arai H, Kobayashi K, Ichimiya Y, Kosaka K, Iizuka R. A preliminary study of free amino acids in postmortem temporal cortex from Alzheimer-type dementia patients. Neurobiol Aging. 5:319-321, 1984
- Arai H, Moroji T, Kosaka K, Iizuka R. Somatostatin and vasoactive intestinal polypeptide in postmortem brains from patients with Alzheimer-type dementia. Neurosci Lett. 52:73-78, 1984
- Arai H, Kobayashi K, Ikeda K, Nagao Y, Ogihara R, Kosaka K. A computed tomography study of Alzheimer's disease. J Neurol. 229:69-77, 1983
JATP関連
- Nomoto H, Hatta K, Usui C, et al.: Vitamin-K deficiency due to prolongation of antibiotic treatment and decrease in food intake in a catatonia patient. Psychosomatics (in press)
- Hatta K, Nakamura H, Usui C, et al.: Utility and sufficiency of psychiatric inpatient units in general hospitals: a cross-sectionalstudy in Tokyo. Psychiatry Clin Neurosci 2010; 64: 642-644
- Ito M, Hatta K, Miyakawa K, et al.: Phenytoin toxicity associated with hypoalbuminemia and the paradoxical elevation of serum concentration. Acta Neuropsychiatrica (in press)
- Hatta K, Otachi T, Sudo Y, et al., for the JAST study group: Difference in early prediction of antipsychotic non-response between risperidone and olanzapine in the treatment of acute-phase schizophrenia. Schizophrenia Research (in press)
- Kishi Y, Kurosawa H, Morimura H, Hatta K, et al.: Attitudes of Japanese nursing personnel toward patients who have attempted suicide. Gen Hosp Psychiatry (in press)
- Usui C, Hatta K, Aratani S, et al.: Japanese version of the 2010 American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and the Fibromyalgia Symptom Scale. Modern Rheumatology (in press)
- Hatta K, Nakamura M, Yoshida K, Hamakawa H, Wakejima T, Nishimura T, Furuta K, Kawabata T, Hirata T, Usui C, Nakamura H, Sawa Y: A prospective naturalistic multicenter study of intravenous medications in behavioral emergencies: haloperidol versus flunitrazepam. Psychiatry Res 178: 182-185, 2010
- Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K, Arai H: Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin. Arthritis Research & Therapy 2010 Apr 7;12(2):R64 .
- Hatta K, Usui C, Nakamura H, Kurosawa H, Arai H: Open wards versus locked wards of general hospitals in the treatment of psychiatric patients with medical comorbidities: a cross-sectional study in Tokyo. Psychiatry Clin Neurosci 64: 52-54, 2010
- Higuchi M, Hatta K, Honma T, Hitomi YH, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Nakamura H: Association between altered systemic inflammatory interleukin-1β and natural killer cell activity and subsequently agitation in patients with Alzheimer disease. Int J Geriatr Psychiatry 25: 604-611, 2010
- Hatta K, Sato K, Hamakawa H, Takebayashi H, Kimura N, Ochi S, Sudo Y, Asukai N, Nakamura H, Usui C, Kawabata T, Hirata T, Sawa Y: Effectiveness of second-generation antipsychotics with acute-phase schizophrenia. Schizophr Res 113: 49-55, 2009
- Ito M, Hatta K, Miyakawa K, Arai H: Pulmonary embolism from persistent dilatation of the bladder secondary to anticholinergic side effects. Gen Hosp Psychiatry 31: 187-189, 2009
- Doi N, Hoshi Y, Itokawa M, Usui C, Yoshikawa T, Tachikawa H:Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint. PLoS One 2009 Nov 11;4(11):e7799.
- Usui C, Hatta K, Kikuchi Y, Arai H: Brain-skin connection: Is atopic dermatitis associated with demonstrable basal ganglia dysfunction? Prog Neuropsychopharmacol Biol Psychiatry 33: 164-165, 2009
- Kamigaichi R, Kubo S, Ishikawa K, Yokoyama K, Ogaki K, Usui C, Hatta K, Arai H, Mochizuki H, Hattori N: Effective control of catatonia in Parkinson’s disease by electroconvulsive therapy: a case report. Eur J Neurol 16: e6, 2009
- Hatta K, Nakamura H, Usui C, Kobayashi T, Kamijo K, Hirata T, Awata S, Kishi Y, Arai H, Kurosawa H: Medical and psychiatric comorbidity at psychiatric beds in general hospitals: a cross-sectional study in Tokyo. Psychiatry Clin Neurosci 63: 329-335, 2009
- Hatta K, Nakamura M, Yoshida K, Hamakawa H, Wakejima T, Nishimura T, Kawabata T, Hirata T, Usui C, Sawa Y: The prevalence of intravenous thiopental use in psychiatric emergency settings in Japan. Psychiatry Clin Neurosci 63: 658-662, 2009
- Sagara T, Hitomi Y, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Ogino K, Hatta K, Nakamura H: Common Risk Factors to Changes in Body Weight and Psychological Well-being in Japanese Male Middle Aged Workers. Environ Health Prev Med 14: 319-327, 2009
- Hatta K, Usui C, Nakamura H: Disturbed homeostasis in patients with acute psychosis. Curr Psychiatry Rev 4: 190-195, 2008
- Hatta K, Kawabata T, Yoshida K, Hamakawa H, Wakejima T, Furuta K, Nakamura M, Hirata T, Usui C, Nakamura H, Sawa Y: Olanzapine orally disintegrating tablet versus risperidone oral solution in the treatment of acutely agitated psychotic patients. Gen Hosp Psychiatry 30: 367-371, 2008
- Usui C, Hatta K, Yokoyama T, Oshima M, Ito M, Shibata N, Arai H: Possible effect of beta-blocker on the prevention of ventricular tachycardia during electroconvulsive therapy. Psychiatry Clin Neurosci 62: 623, 2008
- Hatta K, Kitajima A, Ito M, Usui C, Arai H: Pulmonary edema after electroconvulsive therapy in a patient treated for long-standing asthma with a beta-2 stimulant. J ECT23: 26-27, 2007
- Ito M, Hatta K, Miyakawa K, Miyauchi K, Arai H: Prolonged and fluctuating giant T-wave inversion after electroconvulsive therapy. J ECT23: 194-197, 2007
- Watanabe T, Hatta K, Ota T, Shimo Y, Arai H: A case of central nervous system diseases complicating Mycoplasma pneumoniae. Psychiat Clin Neuros 61: 577, 2007
- Hatta K, Miyakawa K, Ota T, Usui C, Nakamura H, Arai H: Maximal response to electroconvulsive therapy for the treatment of catatonic symptoms. J ECT 23: 233-235, 2007
- Hatta K, Kurosawa H, Arai H: Hospitalization for medical comorbidities among psychiatric patients in Tokyo. Psychiatr Serv 58: 1502, 2007
- Hatta K, Shibata N, Ota T, Usui C, Ito M, Nakamura H, Arai H: Association between physical restraint and drug-induced liver injury. Neuropsychobiology 56: 180-184, 2007
- Doi N, Usui C.: Are high-risk haplotypes in DTNBP1 and NRG1 resistance genes for schizophrenia?: Am J Psychiatry 163:940-941, 2006
- Usui C, Doi N, Nishioka M, Komatsu H, Yamamoto R, Ohkubo T, Ishizuka T, Shibata N, Hatta K, Miyazaki H, Nishioka K, Arai H: Electroconvulsive therapy improves severe pain associated with fibromyalgia. Pain 121: 276-280, 2006
- Watanabe T, Hatta K, Shibata N, Miyakawa K, Asukai N, Arai H: Acute stress symptoms in a victim of the Indian Ocean Tsunami. Psychiat Clin Neuros 60: 644, 2006
- Hatta K: Abnormal physiological conditions due to hypersympathetic activity in psychiatric emergency patients. Gen Hosp Psychiatry 27: 454-456, 2005
- Nakamura H, Matsuzaki I, Sasahara S, Hatta K, et al: Higher sense of coherence as a psychological factor responsible for elevated natural killer cell activity in patients with cedar pollinosis. J Phys Fit Nutr Immunol 14: 25-32, 2004
- Nakamura H, Matsuzaki I, Hatta K, et al: Physiological involvement of placental endothelin-1 and prostaglandin F2α in uteroplacental circulatory disturbance in pregnant rats exposed to heat stress. Canadian Journal of Physiology and Pharmacology 82: 225-230, 2004
- Nakamura H, Higashikawa F, Miyagawa K, Nobukuni Y, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, et al: Association of Single Nucleotide Polymorphisms in the Eosinophil Peroxidase Gene with Japanese Cedar Pollinosis. International Archives of Allergy and Immunology 135: 40-43, 2004
- Hatta K, Nakamura H, Matsuzaki I: Acute-phase treatment in general hospitals: clinical psychopharmacologic evaluation in first-episode schizophrenia patients. Gen Hosp Psychiatry 25: 39-45, 2003
- Nakamura H, Matsuzaki I, Hatta K, et al: Nonthermal effects of mobile-phone frequency microwaves on uteroplacental functions in pregnant rats. Reproductive Toxicology 17: 321-326, 2003
- Nakamura H, Matsuzaki I, Sasahara S, Hatta K, et al: Enhancement of a sense of coherence and natural killer cell activity which occurred in subjects who improved their exercise habits through health education in the workplace. J Occupational Health 45: 278-285, 2003
- Nakamura H, Miyagawa K, Ogino K, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, et al: A High contribution contrast between the genes of eosinophil peroxidase and interleukin 4 receptor α chain in Japanese cedar pollinosis J Allergy Clin Immun 112: 1127-1131, 2003
- Nakamura H, Matsuzaki I, Hatta K, et al: Blood endothelin-1 and cold-induced vasodilatation in patients with primary Raynauld’s phenomenon and workers with vibration-induced white finger. Int Angiol 22: 243-249, 2003
- Hatta K: Emergency pharmacological management of aggression among agitated psychotic patients in Japan. Psychiatric Serv 53: 1077-1078, 2002
- Nakamura H, Nagase H, Ogino K, Hatta K, et al: Involvement of central, but not placental corticotropin releasing hormone (CRH) in heat stress-induced immunosuppression during pregnancy. Brain Behav Immun 15: 43-53, 2001
- Hatta K, Takahashi T, Nakamura H, et al: The association between intravenous haloperidol and prolonged QT interval. J Clin Psychopharmacology 21: 257-61, 2001
- Hatta K, Takahashi T, Nakamura H, et al: Prolonged upper airway instability in parenteral use of benzodiazepine with levomepromazine. J Clin Psychopharmacology 20: 99-101, 2000
- Nakamura H, Nagase H, Ogino K, Hatta K, et al: Heat produces uteroplacental circulatory disturbance in pregnant rats through action of corticotropin releasing hormone (CRH). Placenta 21: 510-515, 2000
- Nakamura H, Nagase H, Ogino K, Hatta K, et al: Uteroplacental circulatory disturbance in pregnant rats exposed to microwaves through actions of prostaglandin F2α. Reprod Toxicol 14: 235-240, 2000
- Hatta K, Takahashi T, Nakamura H, et al: Prolonged QT interval in acute psychotic patients. Psychiatry Res 94: 279-285, 2000
- Hatta K, Takahashi T, Nakamura H, et al: The predictive value of benzodiazepine tolerance in persistently aggressive schizophrenia. Neuropsychobiology 39: 196-199, 1999
- Hatta K, Takahashi T, Nakamura H, et al: Laboratory findings in acute schizophrenia: relevance to medical management on emergency admission. Gen Hosp Psychiatry 21: 220-227, 1999
- Hatta K, Takahashi T, Nakamura H, et al: Hypokalemia and agitation in acute psychotic patients. Psychiatry Res 86: 85-88, 1999
- Hatta K, Miura Y, Asukai N, Hamabe Y: Amnesia from sarin poisoning. Lancet 347: 1343 , 1996
その他
- Kirino E. Prolonged catatonic stupor successfully treated with aripiprazole in an adolescent male with schizophrenia: a case report. Clin Schizophr Relat Psychoses. 2010 Oct;4(3):185-8.
- Sai JK, Suyama M, Kubokawa Y, Matsumura Y, Inami K, Watanabe S, Kirino E. Identification of cerebral response to balloon distention of the bile duct. World J Gastroenterol. 2010 Apr 14;16(14):1772-5.
- Kumagai R, Ichimiya Y: Efficacy of blonanserin in combination therapy for treatment-resistant depression. Psychiatry Clin Neurosci. 63: 593-594, 2009.
- Kawamata M, Kirino E, Arai H, Inoue R: Event-Related Desynchronization of Frontal-Midline Theta Rhythm during Preconscious Auditory Oddball Processing. Clin EEG Neurosci 38 (4) 193-202, 2007
- Murayama N, Iseki E, Yamamoto R, Kimura M, Eto K, Arai H. Utility of the Bender Gestalt Test for Diffrentiation of Dementia with Lewy Bodies from Alzheimer's Disease in Patients Showing Mild to Moderate Dementia. Dement Geriatr Cogn Disord. 23: 258-263, 2007
- Kirino E: P300 is Attenuated during Dissociative Episodes J Nerv Ment Dis 194 (2): 83-90, 2006
- Adachi T, Adachi N, Takekawa Y, Akanuma N, Ito M, Matsubara R, Ikeda H, Kimura M, Arai H. Déjà vu experiences patients with schizophrenia.Comprehensive Psychiatry.47, 389-393 2006
- Adachi T, Masumura T, Arai M, Adanchi N, Akazawa S, Arai H. Self-adaministered Electroconvulsive Treatment With a Homemade Devaice. J ECT.22, 226-227 2006
- Ito M, Baba H, Kawashima R, Arai H. A Case of Prolonged Depression with Tamoxifen. JMAJ.49(4):167-172 2006
- Matsuda K, Ohnuma T, Fukuta M, Kawai M, Suzuki T, Ogawa H, Arai H.Case reports and literature review: The association between reactivation of human herpes virus-6 and peripheral white blood cell count in patients with carbamazepine-induced hypersensitivity syndrome. Prog Neuropsychopharmacol Biol Psychiatry. Jun;30(4):751-4. 2006
- Komatsu S, Kirino E, Inoue Y, and Arai H. Risperidone Withdrawal-Related Respiratory Dyskinesia A Case Diagnosed by Spirography and Fibroscopy. Clin Neuropharmacol 28(2)90-93 2005
- Usui C, Inoue Y, Kimura M, Kirino E, Nagaoka S, Abe M, Nagata T, and Arai H. Irreversible subcortical dementia Following high altitude illness. High altitude medicine & biology.5:77-81 2004
- Kumagai R, Ohnuma T, Nagata T, Arai H. Visual and auditory hallucinations with excessive intake of paroxetine. Psychiatry Clin Neurosci, 57:548-549 2003
- Hirosawa M, Shimada H, Fumimoto H, Eto K, Arai H. Response of Japanese patients to the change of department name for the psychiatric outpatient clinic in a university hospital. Gen Hosp Psychiatry, 24:269-74, 2002
- Inoue Y, Nanba K, Higami S, Honda Y, Takahashi Y, Arai H. Clinical significance of sleep-related breathing disorder in narcopsy. Psychiatry Clin Neurosci, 56:269-270, 2002
- Inoue Y, Nanba K, Hazama G, Takata K, Arai H. Long-term study on patients with sleep apnea syndrome. Psychiatry Clin Neurosci, 55:245-246, 2002
- Inoue Y, Nanba K, kojima K, Mitani H, Arai H. P300 abnormalities in patients with sever sleep apnea syndrome. Psychiatry Clin Neurosci, 55:247-248, 2002
- Inoue Y, Nanba K, Honda Y, Takahashi Y, Arai H. Subjective sleep quality and suggested immobilization test in restless leg syndrome and periodic limb movement disorder. Psychiatry Clin Neurosci, 56:293-294,2002
- Hirosawa M, Nagata T, Arai H. A psychopathological study on elderly Japanese delusional depressives in relation to collapse of traditional Japanese culture. Psychogeriatrics,2:103-112 2002
- Hirosawa M, Arai H, Shimada H. Change of the Department Name for a Psychiatric Out- patient Clinic in a University Hospital. Jap J Gen Hosp Psychiatry, 13:24-31, 2001
和文業績(2010年度 発表分を掲載)
原著・症例報告
- 笠貫浩史, 馬場元, 稲葉真樹, 新井平伊. 水中毒により神経遮断薬性悪性症候群様状態を呈した統合失調症の1例. 精神科治療学,2010;25:267-272.
- 桐野衛二, 福田麻由子, 池田千佐子, 稲見理絵, 新井平伊, 井上令一. 統合失調症患者における表情の動き認知の事象関連電位を用いた検討. 日本薬物脳波学会雑誌,2010;11:63-70.
- 野澤宗央, 藤城弘樹, 野澤詠子, 比賀雅行, 新井友紀, 井関栄三, 一宮洋介, 新井平伊. Quetiapine抵抗性の幻視にaripiprazoleが奏効したレビー小体型認知症の1例. 精神科治療学,2010;25:681-686.
- 赤堀亘, 吉池高志, 桐野衛二. 自傷性皮膚炎の1例. 日本皮膚科学会雑誌,2010;120:1222.
- 笠貫浩史, 藤城弘樹, 村山憲男, 井関栄三. 大うつ病性障害が合併したレビー小体型認知症の1例. 精神科,2010;16:479-484.
- 笠貫浩史, 安宅勇人, 窪倉正一, 鈴木利人, 新井平伊. Risperidone投与中に夜尿と勃起不全を生じblonanserin変更後に軽快した統合失調症の1例. 臨床精神薬理,2010;13:1203-1208.
- 内海雄思, 井関栄三, 村山憲男, 一宮洋介, 新井平伊. インフルエンザワクチン接種後に単純ヘルペスウイルスが原因と考えられる辺緑系脳炎をきたした1症例. BRAIN and NERVE: 神経研究の進歩,2010;62:615-619.
- 熊谷亮, 比賀雅行, 山本涼子, 小松弘幸, 野澤宗央, 一宮洋介. 高齢者病院における糖尿病を合併した認知症入院患者の検討. 精神医学,2010;52:1095-1101.
- 一宮洋介. ドネペジル塩酸塩による治療戦略 進行度に応じた増量のタイミングと薬物治療の中断・終了の目安. 薬局,2010;61:3659-3663.
- 村山憲男, 井関栄三, 太田一実, 藤城弘樹, 長嶋紀一, 佐藤潔, 新井平伊. 意味性認知症の前駆状態と考えられる2症例 もの忘れドックによる早期発見と神経心理的特徴. 老年精神医学雑誌,2010;21:1377-1384.
総説
- 馬場元. 【医療従事者のメンタルヘルスケア】 医療従事者におけるうつ病と自殺 早期介入による自殺防止への取り組み(解説/特集). Nurse eye,2010;23:19-27.
- 熊谷亮, 井関栄三. 【認知症者の尊厳は守られているか】 認知症の身体合併症は適切に治療されているか 一般病棟における身体拘束の課題を含めて. 老年精神医学雑誌,2010;21:22-26.
- 新井平伊. 基礎から臨床へ アルツハイマー病は最良の成功例. 精神科治療学,2010;25:17-21.
- 新井平伊. 【アルツハイマー病治療薬の開発 現在と近未来】 アミロイドワクチンとアルツハイマー病創薬. 日本神経精神薬理学雑誌,2010;30:173-176.
- 八田耕太郎. 【もう困らない!もう迷わない!精神症状を有する救急患者への対応】 精神症状を有する患者への対応を学ぶ!(解説/特集). EMERGENCY CARE,2010;23:135-137.
- 内海雄思, 馬場元, 新井平伊. アルツハイマー型認知症とうつ病の鑑別診断. PTM: 最新の疾患別治療マニュアル2010;3:,9-10.
- 安宅勇人, 鈴木利人, 新井平伊. 基礎・臨床研究の進歩 肥満症の予防・治療学の進歩 特殊な病態における肥満症の診断と治療 精神疾患患者の肥満症の診断と治療. 日本臨床,2010;68:706-710.
- 馬場元, 新井平伊. 認知症とうつ病 初期における鑑別を中心に. 成人病と生活習慣病,2010;40:170-175.
- 八田耕太郎. 【緊張病について 統合失調症か、それとも躁うつ病か】 治療経過からみた緊張病の考察(解説/特集). 日本生物学的精神医学会誌,2010;21:9-12.
- 八田耕太郎. プライマリケアにおける精神科救急の基礎知識(解説). 日本医事新報,2010;4481:75-74.
- 高橋正, 新井平伊. 【精神科後期研修で何を学ぶか?】 老年精神医学. 精神科,2010;16:315-319.
- 新井平伊. 診断 認知症とうつ、せん妄の鑑別. クリニシアン,2010;57:371-374.
- 新井平伊. 認知症をどう診るか?認知症診療の実際 認知症の予防介入はいつ始めるべきか?. Cognition and Dementia,2010;9:71.
- 柴田展人, 新井平伊. 【認知症の発症にかかわる遺伝子】 アミロイド前駆体タンパク. 老年精神医学雑誌,2010;21:514-519.
- 新井平伊. 認知症の診断と鑑別. 日本医師会雑誌,2010;139:652-654.
- 藤城弘樹, 井関栄三. 【高齢者の幻覚妄想 妄想性同定錯誤症候群とその周辺】 高齢者の幻覚妄想と病理学的背景. 老年精神医学雑誌,2010;21:671-676.
- 新井平伊. 【今日の精神科治療ガイドライン】 症状性を含む器質性精神障害 アルツハイマー病の治療. 精神科治療学,2010;25:10-13.
- 井関栄三. 【認知症 研究・臨床の最先端】 臨床トピックス レビー小体型認知症. 医学のあゆみ,2010;235:719-724.
- 村山憲男, 井関栄三, 太田一実, 藤城弘樹, 佐藤潔. レビー小体型認知症の幻視に対する、心理的・環境的介入. 日本認知症ケア学会誌,2010;9: .291.
- 新井平伊. 老年精神医学研究の進め方と発表の仕方 総説論文執筆のコツ. 老年精神医学雑誌,2010;21:707-709.
- 柴田展人, 新井平伊. 【DSM-5ドラフトをどう考えるか】 DSM-5ドラフトにおける認知症(Neurocognitive Disorders). 精神科治療学,2010;25:1001-1004.
- 黄田常嘉, 新井平伊. 【アルツハイマー病(AD)への新たな挑戦 AD治療薬登場後の10年と今後】 認知症/ADの進行に伴う症状・ADL障害に対する治療. Progress in Medicine,2010;30:2115-2119.
- 太田一実, 井関栄三, 村山憲男, 藤城弘樹, 佐藤潔. 幻視に対して心理的介入が有効だったレビー小体型認知症の事例検討. 老年精神医学雑誌,2010;21Suppl:120.
- 八田耕太郎. 統合失調症の急性期薬物療法(解説). Current Insights in Neurological Science,2010;18:5.
- 野澤宗央, 村山憲男, 井関栄三. 【BPSDの疾患別特徴;AD、DLB、FTD】 レビー小体型認知症におけるBPSDの治療と対応. 老年精神医学雑誌,2010;21:879-884.
- 大沼徹, 新井平伊. 【認知症の新しい治療】 薬物治療-BPSD 非定型抗精神病薬の功罪. Modern Physician,2010;30:1161-1164.
- 熊谷亮、山縣真由美, 杉山秀樹, 一宮洋介. アルツハイマー型認知症とうつ病の鑑別に行われる検査の評価 日常の外来で行うことができる検査を中心に. 精神科治療学,2010;25:1249-1255.
- 新井平伊. 初老期アルツハイマー病の病因・病態解明を目指した臨床的アプローチ. 老年期痴呆研究会誌,2010;15:170-171.
- 新井平伊. 初老期アルツハイマー病の病態とその臨床. 老年期痴呆研究会誌,2010;15:172-173.
- 八田耕太郎, 小林孝文, 黒澤尚. 精神医学のフロンティア 身体合併症医療の実態と展望 東京都における前向き全数調査から. 精神神経学雑誌,2010;112:973-979.
- 小松美和, KuerbanBolati, 柴田展人, 大沼徹, 馬場元, 新井平伊. 日本人におけるCLU多型性とアルツハイマー病の遺伝的関連. Dementia Japan,2010;24:314.
- 八田耕太郎. 【救急場面での状態像からみた精神疾患の診断と初期対応】 興奮・錯乱・不安焦燥 精神運動興奮. 月刊レジデント,2010;3:18-22.
- 藤城弘樹, 井関栄三. 【今日の精神科治療ガイドライン】 症状性を含む器質性精神障害 他に分類されるその他の疾患の認知症 クロイツフェルト・ヤコブ病、ハンチントン舞踏病、パーキンソン病、ヒト免疫不全ウイルス(HIV)疾患. 精神科治療学,2010;25:24-27.
- 新井平伊. 【若年性認知症に対する精神科の役割】 若年性認知症とは?. 精神科治療学,2010;25:1277-1280.
- 大沼徹. 私の処方 治療抵抗性統合失調症患者への補充療法. Modern Physician,2010;30:1354.
- 黄田常嘉, 新井平伊. SPECT所見による若年性認知症の鑑別. 日本医事新報,2010;4515:65-68.
- 柴田展人, 新井平伊. 【アルツハイマー病治療薬の現状と期待される治療薬】 免疫療法. 老年精神医学雑誌,2010;21:1348-1352.
- 馬場元. 【加齢とうつ病】 精神医学における老年うつ病の位置づけ(解説/特集). アンチ・エイジング医学,2010;6:818-822.
- 八田耕太郎. なるほどわかった!日常診療のズバリ基本講座(Part 2)(その36) 救急外来で精神疾患・症状をもつ患者さんに出会ったら. レジデントノート,2010;12:2110-2115.
- 村山憲男, 井関栄三. 【認知症診療マニュアル】 認知症の地域医療 各医療機関の特性(得手・不得手)と地域連携の現状・課題 専門病院における物忘れドックの試み. 神経内科,2010;72Suppl:210-212.
- 新井平伊. 【認知症診療マニュアル】 認知症性疾患の遺伝子と病態 神経伝達物質. 神経内科,2010;72:72-76.
- 馬場元. Affection and Cognition 最近の臨床的特徴 高齢者のうつ病 認知症との関係も含めて(解説). 分子精神医学,2010;10:237-238.
- 松原洋一郎, 一宮洋介, 新井平伊. アルツハイマー病 update 危険因子と予防 予防. Clinical Neuroscience,2010;28:1062-1063.
- 藤城弘樹, 井関栄三. ディベート DLBとPDDは同じ病気か違う病気か? 違う病気である. Clinical Neuroscience,2010;28:465.
- 新井平伊. アルツハイマー病のクリティカルパス-診断と治療のために-. 老年期痴呆研究会誌,2010;15:174-175.
報告
- 新井平伊. 「精神医学」への手紙 「若年性」という用語について 柏瀬による「精神医学への手紙」(本誌52巻7号)を読んで(レター). 精神医学,2010;52:1229.
- 野澤宗央, 井関栄三, 一宮洋介, 新井平伊. 遅発性Tourette症候群を呈した認知症の3症例. 老年精神医学雑誌,2010;21:105.
- 八田耕太郎, 佐藤浩司, 濱川浩, 竹林宏, 木村尚人, 越智紳一郎, 須藤康彦, 田端一基, 飛鳥井望, 川畑俊貴, 平田豊明, 臼井千恵, 澤温. 急性期統合失調症に対する第二世代抗精神病薬の有効性の比較. 精神神経学雑誌,2010;特別:184.
- 小松美和, KuerbanBolati, 柴田展人, 大沼徹, 馬場元, 新井平伊.日本人におけるCLU多型性とアルツハイマー病の遺伝的関連. Dementia Japan,2010;24:314.
- 新井平伊. 認知症研究の最近の進歩、三学会それぞれの立場から認知症を極める 若年性認知症の臨床的諸問題. 精神神経学雑誌,2010;S-171.
- 笠貫浩史, 藤城弘樹, 井関栄三, 峯岸道子, 都甲崇, 勝瀬大海, 内門大丈, 東晋二, 日野博昭, 小阪憲司, 佐藤潔, 新井平伊. レビー小体型認知症における脳機能画像所見の神経病理学的背景に関する検討. 老年精神医学雑誌,2010;21:205.
- 比賀雅行, 野澤宗央, 新井友紀, 一宮洋介, 新井平伊. 易怒性、攻撃性を伴う徘徊にparoxetineが著効したアルツハイマー病の2症例. 老年精神医学雑誌,2010;21:130.
- 酒井佳永, 鈴木利人, 新井平伊. 医療機関におけるうつ病患者の復職支援の取り組み プログラム参加者の転帰と効果に関する研究. 日本社会精神医学会雑誌,2010;19:111.
- 小松美和, 柴田展人, 新井平伊. 日本人におけるCLU多型性とアルツハイマー病の遺伝的関連. 順天堂医学,2010;56:501.
- 藤城弘樹, 井関栄三, 村山憲男, 笠貫浩史, 太田一実, 一宮洋介, 新井平伊, 佐藤潔. 18F-FDG PETでびまん性後頭葉糖代謝低下を示す患者の認知機能の多様性について. 老年精神医学雑誌,2010;21:139.
- 新井平伊, 馬場元, 柴田展人. 認知機能障害に影響する意欲と栄養の研究およびそれらにかかわる生化学的指標と遺伝子に関する分子生物学的研究. 順天堂医学,2010;56:376.
- 馬場元. 【気分障害の生物学的理解の最前線】 うつ病から認知症への移行に関わる機序の一考察(解説/特集). 精神神経学雑誌,2010;112:1003-1008.
- 新井友紀, 野澤宗央, 比賀雅行, 窪倉正一, 一宮洋介, 新井平伊. アルツハイマー病に伴う抑うつ状態、食事拒否にaripiprazoleが著効した2症例. 老年精神医学雑誌,2010;21:131.
- 新井平伊. 【若年性認知症に対する精神科の役割】若年性認知症の診断の手順と告知の問題. 精神科治療学,2010;25:1289-1292.
- 新井平伊. 国内外の精神科医療における疾病分類に関する研究-F0領域における検討-. 国内外の精神科医療における疾病分類に関する研究 平成21年度 総括・分担研究報告書,2010;95-98.
- 中村恭子, 廣澤正孝, 岩崎香, 鈴木利人, 湯田京子, 吉田理恵, 木内瑞絵, 輪島留美子. 精神科デイケア通所の統合失調症患者を対象としたダンス・アクティビティの試み 他のスポーツ・プログラムとの比較. 日本病院・地域精神医学会総会抄録集,2010;53回 :98.
- 藤城弘樹, 井関栄三, 東晋二, 笠貫浩史, 村山憲男, 太田一実, 都甲崇, 勝瀬大海, 内門大丈, 青木直哉, 小阪憲司, 新井平伊, 佐藤潔. 大脳アミロイド沈着の分布とレビー小体型認知症における臨床像との相関性(Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia). Dementia Japan,2010;24:321.
その他
- 新井平伊, 繁田雅弘, 朝田隆, 武田雅俊, 斎藤正彦. 新時代の老年精神医学会の目指すところ. 老年精神医学雑誌,2010;21:109-121.
- 村山憲男(順天堂大学医学部附属順天堂東京江東高齢者医療センター), 長嶋紀一. 意味性認知症の前駆状態と考えられる2事例 WAIS-IIIによる意味記憶障害の早期査定. 日本心理学会大会発表論文集74回,2010:393.
- 新井平伊, 鈴木利人, 大澤良郎, 川上保之, 関口隆一. 第二世代抗精神病薬6剤の特徴・使い分けについて. Pharma Medica,2010;28:53-62.

