PROFILE

ARAKI Yoshihiko, M.D., D.Med.Sci.


Deputy Director, Institute for Environmental & Gender-Specific Medicine

Short Biography

1983
M.D. Yamagata University School of Medicine
1987
D.Med.Sci. Yamagata University
1988
Research Associate, Department of Physiology & Biophysics, Case Western Reserve University School of Medicine
1990
Research Instructor, Center for Reproductive Biology, Vanderbilt University School of Medicine
1992-1997
Assistant Professor, Department of Obstetrics & Gynecology, Yamagata University School of Medicine
1997-1999
Associate Professor, Department of Immunology & Parasitology, Yamagata University School of Medicine
1999-2001
Research Associate Professor, Department of Obstetrics & Gynecology, Department of Obstetrics & Gynecology, Vanderbilt University School of Medicine
2001-2004
Associate Professor, Department of Immunology & Parasitology, Yamagata University School of Medicine
2004-Present
Associate Professor, Institute for Environmental & Gender-Specific Medicine, Juntendo University Graduate School of Medicine
2011-Present
Adjunct Associate Professor, Department of Obstetrics & Gynecology, Juntendo University Graduate School of Medicine
2018-Present
Deputy Director, Institute for Environmental & Gender-Specific Medicine, Juntendo University Graduate School of Medicine
2019-Present
Visiting Professor, Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine
 

Keywords

  • Gametogenesis
  • Implantation
  • Fertilization
  • Oviduct
  • GPI-anchored protein
  • Hypertensive disorders of pregnancy

Main Research Topics and Interests

  • Molecular mechanism of mammalian reproduction

Publications (in English)

  • Original Articles: 87
  • Review Articles: 16
  • Books including chapters: 6
  • h-Index: 29 (Web of Science)
  • Sum of Times Cited: 2,673 (Web of Science)

Recent Main Publications (*Correspondence)

  • Okubo M*, Furuta Y, Nakamura Y, Osawa T, Tada N, Sawada T, Yamatoya K, Sekiguchi Y, Araki Y, Miyake K, Noguchi M, Komatsu N, Ohsaka A. A threshold for optimal administration of plerixafor in autologous peripheral blood stem cell collections through CD34+ cell monitoring based on the experience from two Japanese university hospitals. Ther.Apher.Dial. 2020 (published online on Dec. 16, 2020).https://doi.org/10.1111/1744-9987.13614
  • Araki Y*, Yoshitake H, Yamatoya K, Fujiwara H. An overview of sex and reproductive immunity from an evolutionary/anthropological perspective. Immunol.Med. (published online on Oct. 11, 2020). https://doi.org/10.1080/25785826.2020.1831219
  • Yoshitake H, Araki Y.* Role of the glycosylphosphatidylinositol-anchored protein TEX101, and its related molecules in spermatogenesis. Int.J.Mol.Sci. 21, 6628, 2020. doi:10.3390/ijms21186628
  • Araki Y*. Commentary on a "Strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of hypertensive disorders of pregnancy". Clinics Mother Child Health, 17:373. 2020
  • Yamatoya K, Kousaka M, Ito C, Nakata K, Hatano M, Araki Y, Toshimori K. Cleavage of SPACA1 regulates assembly of sperm-egg membrane fusion machinery in mature spermatozoa. Biol.Reprod. 102:750-757, 2020. doi:10.1093/biolre/ioz223
  • Araki Y*, Yanagida M. Hypertensive disorders of pregnancy: strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of this syndrome. In: Adv Clin Chem (Makowski GS. ed.) Vol. 94, pp1-30, Elsevier, London, UK, 2020. (Cover Image: doi: 10.1016/bs.acc.2019.07.007)
  • Fujiwara H*, Ono M, Sato Y, Imakawa K, Iizuka T, Kagami K, Fujiwara T, Horie A, Tani H, Hattori A, Daikoku T, Araki Y. Promoting roles of embryonic signals in embryo implantation and placentation in cooperation with endocrine and immune systems. Int.J.Mol.Sci. 21, 1885, 2020. doi:10.3390/ijms21051885
  • Oda-Sakurai R, Yoshitake H, Miura Y, Kazuno S. Ueno T, Hasegawa A, Yamatoya K, Takamori K, Itakura A, Fujiwara H, Takeda S. Araki Y*. NUP62: the target of an anti-sperm auto-monoclonal antibody during testicular development. Reproduction 158:503-516, 2019.doi: 10.1530/REP-19-0333
  • Yanagida M, Hamamura K, Takamori K, Araki Y*. The simultaneous quantification of candidate serum biomarker peptides for hypertensive disorders of pregnancy. Ann.Clin.Biochem. 56:457-465, 2019. doi: 10.1177/0004563219839084
  • Fujiwara H*, Matsumoto H, Sato Y, Horie A, Ono M, Nakamura M, Mizumoto Y, Kagami K, Fujiwara T, Hattori A, Maida Y, Daikoku T, Imakawa K, Araki Y. Factors regulating human extravillous trophoblast invasion: Chemokine-peptidase and CD9-integrin systems. Cur.Pharm.Biotech. 19: 764-770, 2018. doi: 10.2174/138920101910181112114656
  • Hamamura K, Yanagida M, Ishikawa H, Banzai M, Yoshitake H, Nonaka D, Tanaka K, Sakuraba M, Miyakuni Y, Takamori K, Nojima M, Yoshida K, Fujiwara H, Takeda S, Araki Y*. Quantitative measurement of a candidate serum biomarker peptide derived from α2-HS-glycoprotein, and a preliminary trial of multi-dimensional peptide analysis in women with pregnancy induced hypertension. Ann.Clin.Biochem. 55:287-295, 2018. doi: 10.1177/000456321771774814:40
  • More

Other Specific Comments Major Committee Assignment

  • International Society for Immunology of Reproduction
  • Society for the Study of Reproduction
  • Japan Society of Obstetrics and Gynecology
  • Japan Society for Immunology of Reproduction
  • American Society of Andrology
  • Japan Society for Immunology
  • The Society for Reproduction and Development
  • Japanese Society for the History of Medicine

Editorial Board

  • The Open Reproductive Science Journal (2007-2015)
  • Scientific Reports (2014-Present)

Reviewer (1992-Present)

Biology of Reproduction, Human Reproduction, Zygote, Reproduction, Molecular Reproduction & Development, Immunobiology, FEBS Journal (European Journal of Biochemistry), Journal of Andrology, Journal of Biosciences, Journal of Molecular Histology, Cancer Letter, Journal of Molecular Endocrinology, Molecular Biology Reports, Reproductive BioMedicine Online, Environmental Health and Preventive Medicine, The Open Medical Informatics Journal, British Journal of Cancer, International Journal of Developmental Biology, International Journal of Food Sciences & Nutrition, Gene, International Journal of Andrology, Journal of Cell Science, Clinical & Experimental Immunology, Immunology, Journal of Reproductive Immunology, Annals of Medicine, Journal of Obstetrics and Gynaecology Research, The Open Reproductive Science Journal, Molecular Human Reproduction, Biochemistry Research International, International Journal of Biological Markers, Scientific Reports, PLOS ONE, Livestock Science, Japanese Journal for History of Medicine, The Protein Journal, Studies in Natural Products Chemistry -Bioactive Natural Products- (Ed:Atta-ur-Rahman, Elsevier Science), Cytokine, American Journal of Reproductive Immunology, Reproduction Fertility and Development, Experimental Dermatology, Molecular & Cellular Proteomics, Medical Hypotheses

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