PROFILE

HIOKI Hiroyuki, M.D., Ph.D.


Department of Neuroanatomy

Short Biography

2003
M.D., Kyoto University Faculty of Medicine
2005.01-2017.10
Assistant Professor, Department of Morphological Brain Science, Kyoto University Graduate School of Medicine
2008
Ph.D., Kyoto University Graduate School of Medicine
2014.05-Present
Visiting Researcher, RIKEN Center for Brain Science
2017.11-2021.04
Associate Professor, Juntendo University Faculty of Medicine
2017.11-2020.03
Part-Time Lecturer, Kyoto University Faculty of Medicine
2019.04-Present
Part-Time Lecturer, The University of Tokyo Faculty of Medicine
Part-Time Lecturer, Hokkaido University Graduate School of Medicine
2020.04-Present
Visiting Researcher, Kyoto University Graduate School of Medicine
2020.10-Present
Visiting Researcher, The Jikei University School of Medicine
2020.11-Present
PI, Department of Multi-Scale Brain Structure Imaging, Juntendo University Graduate School of Medicine (Endowed Research Section)
2021.05-Present
Professor, Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine
2021.07-Present
Professor, Department of Neuroanatomy, Juntendo University Graduate School of Medicine
 

Keywords

  • Neuronal Circuit
  • Central Nervous System
  • Neocortex
  • Neuroanatomy
  • Bioimaging

Main Research Topics and Interests

  • Local circuit of the neocortex
  • Neuronal circuit analysis of the central nervous system
  • Morphological analysis of mouse disease models
  • Morphological and physiological plasticity in learning
  • Development of innovative bioimaging tools (e.g., virus vectors and tissue-clearing technique)

Publications (in English)

  • Original Articles: 76
  • Review Articles: 1
  • Books: 3
  • h-index: 33 (Scopus)
  • Sum of Times Cited: 5,081 (Scopus)

Recent Main Publications

  • Okamoto S, Yamauchi K, Sohn J, Takahashi M, Ishida Y, Furuta T, Koike M, Fujiyama F, *Hioki H. (2021) Exclusive labeling of direct and indirect pathway neurons in the mouse neostriatum by an adeno-associated virus vector with Cre/lox system. STAR Protoc. 2(1):100230. PMID:33364620, doi:10.1016/j.xpro.2020.100230
  • Okamoto K, Ebina T, Fujii N, Konishi K, Sato Y, Kashima T, Nakano R, Hioki H, Takeuchi H, Yumoto J, Matsuzaki M, *Ikegaya Y. (2021) Tb(3+)-doped fluorescent glass for biology. Sci Adv. 7(2):eabd2529. PMID:33523970, doi:10.1126/sciadv.abd252
  • Ota K, Oisi Y, Suzuki T, Ikeda M, Ito Y, Ito T, Uwamori H, Kobayashi K, Kobayashi M, Odagawa M, Matsubara C, Kuroiwa Y, Horikoshi M, Matsushita J, Hioki H, Ohkura M, Nakai J, Oizumi M, Miyawaki A, Aonishi T, Ode T, *Murayama M. (2021) Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas. Neuron. 109(11):1810-1824. PMID:33878295, doi:10.1016/j.neuron.2021.03.032
  • Chen S, He L, Huang AJY, Boehringer R, Robert V, Wintzer ME, Polygalov D, Weitemier AZ, Tao Y, Gu M, Middleton SJ, Namiki K, Hama H, Therreau L, Chevaleyre V, Hioki H, Miyawaki A, Piskorowski RA, *McHugh TJ. (2020) A hypothalamic novelty signal modulates hippocampal memory. Nature. 586(7828):270-274. PMID:32999460, doi:10.1038/s41586-020-2771-1
  • Katayama H, Hama H, Nagasawa K, Kurokawa H, Sugiyama M, Ando R, Funata M, Yoshida N, Homma M, Nishimura T, Takahashi M, Ishida Y, Hioki H, Tsujihata Y, *Miyawaki A. (2020) Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration. Cell. 181(5):1176-1187. PMID:32437660, doi:10.1016/j.cell.2020.04.025
  • Okamoto S, Sohn J, Tanaka T, Takahashi M, Ishida Y, Yamauchi K, Koike M, Fujiyama F, *Hioki H. (2020) Overlapping Projections of Neighboring Direct and Indirect Pathway Neostriatal Neurons to Globus Pallidus External Segment. iScience. 23(9):101409. PMID:32877648, doi:10.1016/j.isci.2020.101409
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