HIRAMATSU Keiichi, M.D., Ph.D.

Emeritus Professor, Microbiology
Director, Center of Excellence for Infection Control Science

Short Biography

M.D. The University of Tokyo Faculty of Medicine
Practiced internal medicine
Research student in Immunology at Tokyo University and Massachusetts Institute of Technology (MIT)
Assistant Professor in Retrovirology at Tokyo University and Tokyo Medical and Dental University
Associate Professor, Department of Microbiology, Juntendo University Faculty of Medicine
Professor, Department of Microbiology, Juntendo University Faculty of Medicine
Director of Infection Control Science Research Center at Juntendo University

Main Research Topics and Interests

  • Discovery of staphylococcal cassette chromosome mec (SCCmec) as the genetic determinant of MRSA (1995), Discovery of vancomycin-intermediate Staphylococcus (S.) aureus (VISA) and heterogeneously intermediate-VISA (hVISA) (1997), The first whole genome sequence determination of S. aureus (N315 and Mu50)(2001) (ref. 6), then of CA-MRSA strain MW2 (2002), Proposal of the novel mechanism ‘peptidoglycan clogging’ for the vancomycin resistance of VISA (2006)
  • Discovery of the origin of mecA gene in S. flurettii (2010), Discovery of Reverse Antibiotic (2012)
  • Antibiotics, Antibiotic resistance, Microbiology of MRSA, Micorbial Genomics, Infection Control
  • Reverse Antibiotics, ß-lactam Resistance, Vancmycin resistance, Molecular Epidemiology of Staphylococcus aureus. Anti-MRSA chemotoerapy

Publications (in English)

  • Original Articles (222)
  • Review Articles (20)
  • Book (24)
  • Total Impact Factor (Top 50) (355.589)
  • Citation Index (20,476)

Recent Main Publications

  • Hiramatsu K, Ito T, Tsubakishita S, Sasaki T, Takeuchi F, Morimoto Y, Katayama Y, Matsuo M, Kuwahara-Arai K, Hishinuma T, Baba T: Genomic Basis for Methicillin Resistance in Staphylococcus aureus. Infect Chemother, 2013 Jun; 45 (2): 117-36.
  • Hiramatsu K, Katayama Y, Matsuo M, Sasaki T, Morimoto Y, Sekiguchi A, Baba T: Multi-Drug-Resistant Staphylococcus aureus and Future Chemotherapy. J Infect Chemother, 2014 Oct; 20 (10): 593-601.
  • Hiramatsu K, Katayama Y, Matsuo M, Aiba Y, Saito M, Hishinuma T, Iwamoto A: Vancomycin-intermediate resistance in Staphylococcus aureus. J Glob Antimicrob Resist; 2014 Dec; 2 (4) : 213-224.
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