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草生真規雄（クサオイマキオ）

研究テーマ	血漿交換療法の効果発現メカニズムの解明
研究業績（論文）	Combination therapy with plasma exchange and glucocorticoid may be effective for severe COVID-19 infection: A retrospective observational study. Matsushita Y, Kusaoi M, Hiki M, Murayama G, Abe Y, Nozawa K, Takahashi K, Yamaji K, Tamura N, Naito T. Ther Apher Dial. 2021 Apr 22. Online ahead of print. Reimbursement for therapeutic apheresis devices and procedures for using the healthcare insurance system in Japan. Kusaoi M, Murayama G, Tamura N, Yamaji K. Ther Apher Dial. 2020 Oct;24(5):530-547. Changes in the Expression of Circulating microRNAs in Systemic Lupus Erythematosus Patient Blood Plasma After Passing Through a Plasma Adsorption Membrane. Ishibe Y, Kusaoi M, Murayama G, Nemoto T, Kon T, Ogasawara M, Kempe K, Yamaji K, Tamura N. Ther Apher Dial. 2018 Jun;22(3):278-289. Separation of Circulating MicroRNAs Using Apheresis in Patients With Systemic Lupus Erythematosus. Kusaoi M, Yamaji K, Ishibe Y, Murayama G, Nemoto T, Sekiya F, Kon T, Ogasawara M, Kempe K, Tamura N, Takasaki Y. Ther Apher Dial. 2016 Aug;20(4):348-53. Safety and efficacy of the leukocytapheresis procedure in eighty-five patients with rheumatoid arthritis. Kitagaichi M, Kusaoi M, Tsukahara T, Murayama G, Nemoto T, Sekiya F, Kon T, Ogasawara M, Kempe K, Yamaji K, Tamura N, Tsuda H, Takasaki Y. Transfus Apher Sci. 2016 Oct;55(2):225-232. Reduction in bradykinin generation during leukocytapheresis using novel cellsorba(TM) CS-180S: Effects of changing the filling solution. Yamada R, Kusaoi M, Murayama G, Yasui M, Hishinuma R, Nemoto T, Hohtatsu K, Kageyama M, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Yamaji K, Tsuda H, Takasaki Y. J Clin Apher. 2014 Apr;29(2):90-6. Gene expression analysis using a high-resolution DNA microarray of peripheral whole blood immediately before and after leukocytapheresis for rheumatoid arthritis.:Kusaoi M, Yamaji K, Murayama G, Yasui M, Yamada R, Hishinuma R, Nemoto T, Hohtatsu K, Kageyama M, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Tsuda H, Takasaki Y.:Ther Apher Dial;2012;16(5):456-66. Effect of various anticoagulant agents on large-volume leukocytapheresis using new Cellsorba CS-180S Filter.:Hohtatsu K, Yamaji K, Yamada R, Oda K, Kageyama M, Kusaoi M, Onuma S, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Tsuda H, Takasaki Y.:Ther Apher Dial; 2011;15(4):355-9. Autofeedback from ultrasound images provides rapid improvement in palpation skills for identifying joint swelling in rheumatoid arthritis.;Ogasawara M, Murayama G, Yamada Y, Nemoto T, Kageyama M, Toyama S, Kusaoi M, Onuma S, Kon T, Sekiya F, Sugimoto K, Matsudaira R, Matsushita M, Tada K, Kempe K, Yamaji K, Tamura N, Takasaki Y.:J Rheumatol;2012;39(6):1207-14. Recent trends in use of nonbiologic DMARDs and evaluation of their continuation rates in single and dual combination therapies in rheumatoid arthritis patients in Japan.;Ogasawara M, Kageyama M, Kusaoi M, Onuma S, Kon T, Sekiya F, Sugimoto K, Matsudaira R, Matsushita M, Tada K, Kempe K, Yamaji K, Tamura N, Takasaki Y.:Mod Rheumatol;2012 Nov;22(6):831-6. Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis.;Ogasawara M, Tamura N, Kageyama M, Onuma S, Kusaoi M, Toyama S, Sekiya F, Matsudaira R, Nawata M, Tada K, Matsushita M, Kempe K, Amano H, Morimoto S, Yamaji K, Takasaki Y.:Clin Rheumatol;2012;31(2):251-7. Association of Functional Polymorphisms in Interferon Regulatory Factor 2 (IRF2) with Susceptibility to Systemic Lupus Erythematosus: A Case-Control Association Study. Kawasaki A, Furukawa H, Nishida N, Warabi E, Kondo Y, Ito S, Matsumoto I, Kusaoi M, Amano H, Suda A, Nagaoka S, Setoguchi K, Nagai T, Hirohata S, Shimada K, Sugii S, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Okamoto A, Kono H, Tokunaga K, Takasaki Y, Hashimoto H, Sumida T, Tohma S, Tsuchiya N. PLoS One. 2014 Oct 6;9(10):e109764. Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB113:02 and 14:03. Furukawa H, Kawasaki A, Oka S, Ito I, Shimada K, Sugii S, Hashimoto A, Komiya A, Fukui N, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Amano H, Nagai T, Hirohata S, Setoguchi K, Kono H, Okamoto A, Chiba N, Suematsu E, Katayama M, Migita K, Suda A, Ohno S, Hashimoto H, Takasaki Y, Sumida T, Nagaoka S, Tsuchiya N, Tohma S. PLoS One. 2014 Feb 3;9(2):e87792. Association of a single nucleotide polymorphism in the SH2D1A intronic region with systemic lupus erythematosus. Furukawa H, Kawasaki A, Oka S, Shimada K, Matsui T, Ikenaka T, Hashimoto A, Okazaki Y, Takaoka H, Futami H, Komiya A, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Nagai T, Hirohata S, Setoguchi K, Suda A, Nagaoka S, Kono H, Okamoto A, Chiba N, Suematsu E, Fukui N, Hashimoto H, Sumida T, Ono M, Tsuchiya N, Tohma S. Lupus. 2013 Apr;22(5):497-503. Cumulative association of eight susceptibility genes with systemic lupus erythematosus in a Japanese female population.;Koga M, Kawasaki A, Ito I, Furuya T, Ohashi J, Kyogoku C, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N.:J Hum Genet;2011;56(7):503-7. TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study.;Kawasaki A, Furukawa H, Kondo Y, Ito S, Hayashi T, Kusaoi M, Matsumoto I, Tohma S, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N.:Arthritis Res Ther;2011;13(2):R41. Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.;Hikami K, Kawasaki A, Ito I, Koga M, Ito S, Hayashi T, Matsumoto I, Tsutsumi A, Kusaoi M, Takasaki Y, Hashimoto H, Arinami T, Sumida T, Tsuchiya N.:Arthritis Rheum;2011;63(3):755-63. Association of a functional polymorphism in the 3' untranslated region of SPI1 with systemic lupus erythematosus.;Hikami K, Kawasaki A, Ito I, Koga M, Ito S, Hayashi T, Matsumoto I, Tsutsumi A, Kusaoi M, Takasaki Y, Hashimoto H, Arinami T, Sumida T, Tsuchiya N.:Arthritis Rheum. 2010 Dec 15. [Epub ahead of print] Observational cross-sectional study revealing less aggressive treatment in Japanese elderly than nonelderly patients with rheumatoid arthritis.;Ogasawara M, Tamura N, Onuma S, Kusaoi M, Sekiya F, Matsudaira R, Kempe K, Yamaji K, Takasaki Y.:J Clin Rheumatol;2010;16(8):370-4. Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study.;Kawasaki A, Ito S, Furukawa H, Hayashi T, Goto D, Matsumoto I, Kusaoi M, Ohashi J, Graham RR, Matsuta K, Behrens TW, Tohma S, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N.:Arthritis Res Ther;2010;12(5):R174.

研究テーマ

血漿交換療法の効果発現メカニズムの解明

研究業績（論文）

Combination therapy with plasma exchange and glucocorticoid may be effective for severe COVID-19 infection: A retrospective observational study.
Matsushita Y, Kusaoi M, Hiki M, Murayama G, Abe Y, Nozawa K, Takahashi K, Yamaji K, Tamura N, Naito T.
Ther Apher Dial. 2021 Apr 22. Online ahead of print.

Reimbursement for therapeutic apheresis devices and procedures for using the healthcare insurance system in Japan.
Kusaoi M, Murayama G, Tamura N, Yamaji K.
Ther Apher Dial. 2020 Oct;24(5):530-547.

Changes in the Expression of Circulating microRNAs in Systemic Lupus Erythematosus Patient Blood Plasma After Passing Through a Plasma Adsorption Membrane.
Ishibe Y, Kusaoi M, Murayama G, Nemoto T, Kon T, Ogasawara M, Kempe K, Yamaji K, Tamura N.
Ther Apher Dial. 2018 Jun;22(3):278-289.

Separation of Circulating MicroRNAs Using Apheresis in Patients With Systemic Lupus Erythematosus.
Kusaoi M, Yamaji K, Ishibe Y, Murayama G, Nemoto T, Sekiya F, Kon T, Ogasawara M, Kempe K, Tamura N, Takasaki Y.
Ther Apher Dial. 2016 Aug;20(4):348-53.

Safety and efficacy of the leukocytapheresis procedure in eighty-five patients with rheumatoid arthritis.
Kitagaichi M, Kusaoi M, Tsukahara T, Murayama G, Nemoto T, Sekiya F, Kon T, Ogasawara M, Kempe K, Yamaji K, Tamura N, Tsuda H, Takasaki Y.
Transfus Apher Sci. 2016 Oct;55(2):225-232.

Reduction in bradykinin generation during leukocytapheresis using novel cellsorba(TM) CS-180S: Effects of changing the filling solution.
Yamada R, Kusaoi M, Murayama G, Yasui M, Hishinuma R, Nemoto T, Hohtatsu K, Kageyama M, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Yamaji K, Tsuda H, Takasaki Y.
J Clin Apher. 2014 Apr;29(2):90-6.

Gene expression analysis using a high-resolution DNA microarray of peripheral whole blood immediately before and after leukocytapheresis for rheumatoid arthritis.:Kusaoi M, Yamaji K, Murayama G, Yasui M, Yamada R, Hishinuma R, Nemoto T, Hohtatsu K, Kageyama M, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Tsuda H, Takasaki Y.:Ther Apher Dial;2012;16(5):456-66.

Effect of various anticoagulant agents on large-volume leukocytapheresis using new Cellsorba CS-180S Filter.:Hohtatsu K, Yamaji K, Yamada R, Oda K, Kageyama M, Kusaoi M, Onuma S, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Tsuda H, Takasaki Y.:Ther Apher Dial; 2011;15(4):355-9.

Autofeedback from ultrasound images provides rapid improvement in palpation skills for identifying joint swelling in rheumatoid arthritis.;Ogasawara M, Murayama G, Yamada Y, Nemoto T, Kageyama M, Toyama S, Kusaoi M, Onuma S, Kon T, Sekiya F, Sugimoto K, Matsudaira R, Matsushita M, Tada K, Kempe K, Yamaji K, Tamura N, Takasaki Y.:J Rheumatol;2012;39(6):1207-14.

Recent trends in use of nonbiologic DMARDs and evaluation of their continuation rates in single and dual combination therapies in rheumatoid arthritis patients in Japan.;Ogasawara M, Kageyama M, Kusaoi M, Onuma S, Kon T, Sekiya F, Sugimoto K, Matsudaira R, Matsushita M, Tada K, Kempe K, Yamaji K, Tamura N, Takasaki Y.:Mod Rheumatol;2012 Nov;22(6):831-6.

Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis.;Ogasawara M, Tamura N, Kageyama M, Onuma S, Kusaoi M, Toyama S, Sekiya F, Matsudaira R, Nawata M, Tada K, Matsushita M, Kempe K, Amano H, Morimoto S, Yamaji K, Takasaki Y.:Clin Rheumatol;2012;31(2):251-7.

Association of Functional Polymorphisms in Interferon Regulatory Factor 2 (IRF2) with Susceptibility to Systemic Lupus Erythematosus: A Case-Control Association Study.
Kawasaki A, Furukawa H, Nishida N, Warabi E, Kondo Y, Ito S, Matsumoto I, Kusaoi M, Amano H, Suda A, Nagaoka S, Setoguchi K, Nagai T, Hirohata S, Shimada K, Sugii S, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Okamoto A, Kono H, Tokunaga K, Takasaki Y, Hashimoto H, Sumida T, Tohma S, Tsuchiya N.
PLoS One. 2014 Oct 6;9(10):e109764.

Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1*13:02 and *14:03.
Furukawa H, Kawasaki A, Oka S, Ito I, Shimada K, Sugii S, Hashimoto A, Komiya A, Fukui N, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Amano H, Nagai T, Hirohata S, Setoguchi K, Kono H, Okamoto A, Chiba N, Suematsu E, Katayama M, Migita K, Suda A, Ohno S, Hashimoto H, Takasaki Y, Sumida T, Nagaoka S, Tsuchiya N, Tohma S.
PLoS One. 2014 Feb 3;9(2):e87792.

Association of a single nucleotide polymorphism in the SH2D1A intronic region with systemic lupus erythematosus.
Furukawa H, Kawasaki A, Oka S, Shimada K, Matsui T, Ikenaka T, Hashimoto A, Okazaki Y, Takaoka H, Futami H, Komiya A, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Nagai T, Hirohata S, Setoguchi K, Suda A, Nagaoka S, Kono H, Okamoto A, Chiba N, Suematsu E, Fukui N, Hashimoto H, Sumida T, Ono M, Tsuchiya N, Tohma S.
Lupus. 2013 Apr;22(5):497-503.

Cumulative association of eight susceptibility genes with systemic lupus erythematosus in a Japanese female population.;Koga M, Kawasaki A, Ito I, Furuya T, Ohashi J, Kyogoku C, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N.:J Hum Genet;2011;56(7):503-7.

TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study.;Kawasaki A, Furukawa H, Kondo Y, Ito S, Hayashi T, Kusaoi M, Matsumoto I, Tohma S, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N.:Arthritis Res Ther;2011;13(2):R41.

Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.;Hikami K, Kawasaki A, Ito I, Koga M, Ito S, Hayashi T, Matsumoto I, Tsutsumi A, Kusaoi M, Takasaki Y, Hashimoto H, Arinami T, Sumida T, Tsuchiya N.:Arthritis Rheum;2011;63(3):755-63.

Association of a functional polymorphism in the 3' untranslated region of SPI1 with systemic lupus erythematosus.;Hikami K, Kawasaki A, Ito I, Koga M, Ito S, Hayashi T, Matsumoto I, Tsutsumi A, Kusaoi M, Takasaki Y, Hashimoto H, Arinami T, Sumida T, Tsuchiya N.:Arthritis Rheum. 2010 Dec 15. [Epub ahead of print]

Observational cross-sectional study revealing less aggressive treatment in Japanese elderly than nonelderly patients with rheumatoid arthritis.;Ogasawara M, Tamura N, Onuma S, Kusaoi M, Sekiya F, Matsudaira R, Kempe K, Yamaji K, Takasaki Y.:J Clin Rheumatol;2010;16(8):370-4.

Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study.;Kawasaki A, Ito S, Furukawa H, Hayashi T, Goto D, Matsumoto I, Kusaoi M, Ohashi J, Graham RR, Matsuta K, Behrens TW, Tohma S, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N.:Arthritis Res Ther;2010;12(5):R174.

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【学校法人順天堂】研究者情報データベース

研究業績詳細

草生 真規雄（クサオイ マキオ）

草生真規雄（クサオイマキオ）