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研究業績詳細

清水 俊明(シミズ トシアキ)

研究テーマ 新生児・小児の栄養・消化器病学
研究業績(論文) 教育実践上の主な業績
1.教育内容方法の工夫
2004年~現在 PCの使用により画像を多く取り入れた授業を行う
2004年~現在 学生からの授業評価に対するフィードバックを行う


2.作成した教科書、教材、参考書等
2005年5月 研修医のテキスト「研修医のための小児科診療500問」
2007年4月 小児科学のテキスト「小児科学・新生児学テキスト」
2007年4月 小児科医向けのテキスト「小児科診療ガイドライン」
2008年2月 学生用テキスト「講義録 小児科学」
2008年4月 小児科医向けのテキスト「小児科学」
2009年4月 小児科医向けのテキスト「小児科臨床ガイド」
2010年5月 小児科医向けのテキスト「小児科臨床ピクシス 下痢・便秘」
2011年1月 小児科医向けのテキスト「小児臨床栄養学」
2011年4月 小児科医向けのテキスト「小児科学」
2011年11月 小児科医向けのテキスト「子育て支援ハンドブック」
2012年1月 医師向けのテキスト「今日の治療指針」
2012年2月 小児科医向けのテキスト「今日の小児治療指針」
2012年2月 小児科医向けのテキスト「ビジュアル小児疾患診断のコツ」
2012年8月 小児科医向けのテキスト「小児生活習慣病ハンドブック」
2012年8月 小児科医向けのテキスト
       「最新ガイドライン準拠 小児科診断・治療指針」
2013年1月 小児科医向けのテキスト「臨床病態学 小児編」
2015年4月 小児科医向けテキスト「ネルソン小児科学」
2018年4月 小児科外来処方マニュアル
2019年2月 国際診療のための小児科アトラス辞典


3.教育方法・教育実践に関する発表、講演等
2003年~2017年 成田医学教育ワークショップにて卒前・卒後の教育方法などにつき世話人として討論


4.その他教育活動上特記すべき事項
2003年~2017年 医学部教務委員会 委員として活動(2011年、2017年に委員長)
2004年~現在  卒業支援委員会 委員として活動(2011年まで委員長)
2005年~2014年  大学院医学研究科基盤センター超微形態研究部門 運営委員長として活動
2005年~2017年 医学部カリキュラム委員会 委員として活動(2016年まで委員長)
2006年~2021年  医学部学生部委員会 委員として活動
2003年~2010年 医学部同窓会 学生会員理事として活動
2018年~2019年 医学部研究委員会委員長
2021年~2022年 医学部教務委員会委員長


研究業績
原著
Akiya A, Takahashi K, Akimoto S, Hosono Y, Ifuku M, Iso T, Yazaki K, Shigemitsu S, Jimbo K, Kudo T, Ohtsuka Y, Shimizu T. Novel findings of early cardiac dysfunction in patients with childhood-onset inflammatory bowel disease using layer-specific strain analysis. Inflamm Bowel Dis, in press.

Isayama H, ishii S, Suzuki M, Shimizu T. From cradle to grave: seamless management of chronic pancreatitis but consider the special requests for children. Hepatobiliary Surg Nutr, in press.

Narita C, Nishizaki N, Takubo N, Shimura N, Shimizu T. Graves' disease following nephrotic syndrome treated by PSL: A case report. Pediatr Int, in press.

Suzuki M, Hirai S, Sakurai Y, Shimizu T. Does the complex of CELA3B variants with other pancreatitis-related genes affect developing childhood pancreatitis?. J Pediatr Gastroenterol Nutr, in press.

Suzuki M, Hirai S, Sakurai Y, Shimizu T. Does the complex of CELA3B variants with other pancreatitis-related genes affect developing childhood pancreatitis?. J Pediatr Gastroenterol Nutr, in press.

Arai Y, Shoji H, Awata K, Inage E, Ikuse T, Shimizu T. Evaluation of the use of non-invasive hemoglobin measurement in early childhood. Pediatr Res 93(4):1036-1040. 2023

Arai Y, Shoji H, Santosa I, Awata K, Tokita K, Shimizu T. Effects of fetal growth restriction on postnatal gut microbiota in a rat model. J Pediatr Gastroenterol Nutr 77(2):e42-e47.2023

Fukuda S, Suzuki M, Minowa K, Koga H, Yamataka A, Shimizu T. Pediatric pancreatic endocrine tumor presenting as acute pancreatitis: A case report. Children (Basel) 10(5):900. 2023

Gonda Y, Matsuda A, Adachi K, Ishii C, Suzuki M, Osaki A, Mita M, Nishizaki N, Ohtomo Y, Shimizu T, Yasui M, Hamase K, Sasabe J. Mammals sustain amino acid homochirality against chiral conversion by symbiotic microbes. P Natl Acad Sci USA 120(15):e2300817120. 2023

Hirai S, Suzuki M, Sakurai Y, Nakano S, Minowa K, Eguchi H, Okazaki Y, Shimizu T. The coexistence of TRPV6 variants with other pancreatitis-associated genes affects pediatric-onset pancreatitis. J Pediatr Gastroenterol Nut 76(4):483-488. 2023

Igami K, Hosozawa M, Ikeda A, Bann D, Shimizu T, Iso H. Adolescent loneliness in 70 countries across Africa, America, and Asia: A comparison of prevalence and correlates. J Adolesc Health 72(6):906-913.2023

Ikeda N, Shoji H, Ikuse T, Ohkawa N, Kashiwagi K, Saito Y, Shimizu T. A case of neonatal thrombocytopenia due to maternal Helicobacter pylori-associated immune thrombocytopenia. Helicobacter 28(3):e12976. 2023

Ishige T, Shimizu T, Watanabe K, Arai K, Kamei K, Kudo T, Kunisaki R, Tokuhara D, Naganuma M, Mizuochi T, Murashima A, Inoki Y, Iwata N, Iwama I, Koinuma S, Shimizu H, Jimbo K, Takaki Y, Takahashi S, Cho Y, Nambu R, Nishida D, Hagiwara SI, Hikita N, Fujikawa H, Hosoi K, Hosomi S, Mikami Y, Miyoshi J, Yagi R, Yokoyama Y, Hisamatsu T. Correction to: Expert consensus on vaccination in patients with inflammatory bowel disease in Japan. J Gastroenterol 58(4):431-432. 2023

Ishige T, Shimizu T, Watanabe K, Arai K, Kamei K, Kudo T, Kunisaki R, Tokuhara D, Naganuma M, Mizuochi T, Murashima A, Inoki Y, Iwata N, Iwama I, Koinuma S, Shimizu H, Jimbo K, Takaki Y, Takahashi S, Cho Y, Nambu R, Nishida D, Hagiwara SI, Hikita N, Fujikawa H, Hosoi K, Hosomi S, Mikami Y, Miyoshi J, Yagi R, Yokoyama Y, Hisamatsu T. Expert consensus on vaccination in patients with inflammatory bowel disease in Japan. J Gastroenterol. 58(2):135-157. 2023

Jimbo K, Hosoi K, Suzuki M, Kyodo R, Maruyama K, Arai N, Sato M, Miyata E, Hoshino E, Kudo T, Shimizu T. Accuracy of transperineal ultrasonography for assessing rectal lesions in pediatric ulcerative colitis: A prospective study. J Crohns Colitis 17(7):1122-1127.2023

Kimura K, Jimbo K, Arai N, Sato M, Suzuki M, Kudo T, Yano T, Shimizu T. Eosinophilic enteritis requiring differentiation from chronic enteropathy associated with SLCO2A1 gene: A case report. World J Gastroenterol 29(11):1757-1764. 2023

Kubo Y, Miura T, Obinata K, Hisata K, Suzuki M, Inage E, Yanagisawa N, Shoji H, Ogata N, Shibata J, Shibata T, Shimizu T. Relationship between COVID-19 and use of chlorine dioxide gasreleasing agents in elementary schools. Glob J Med Res 23:1-5. 2023

Kudo T, Shimizu T. Mucosal immune systems of pediatric inflammatory bowel disease: A review. Pediatr Int 65(1):e15511.2023

Murano Y, Yamahira S, Shoji H, Hisata K, Koshizaka T, Nakazawa T, Shimizu T, Rahman M. Evaluation of the transmission of SARS-CoV-2 through breast milk: a case series. Front Pediat 11:1160790.2023

Nagata M, Jimbo K, Arai N, Kashiwagi K, Tokushima K, Suzuki M, Kudo T, Shimizu T. An isolated intestinal juvenile polyp diagnosed by abdominal ultrasonography and resected by double-balloon endoscopy: A case report and literature review. Diagnostics (Basel) 13(3):494. 2023

Nambu R, Arai K, Kudo T, Murakoshi T, Kunisaki R, Mizuochi T, Kato S, Kumagai H, Inoue M, Ishige T, Saito T, Noguchi A, Yodoshi T, Hagiwara SI, Iwata N, Nishimata S, Kakuta F, Tajiri H, Hiejima E, Toita N, Mochizuki T, Shimizu H, Iwama I, Hirano Y, Shimizu T; JPIBD-R. Clinical outcome of ulcerative colitis with severe onset in children: a multicenter prospective cohort study. J Gastroenterol 58(5):472-480. 023

Nishizaki N, Tsuji S, Akagawa S, Hirano D, Takahashi K, Shimizu T, Kaneko K. Comparison of the characteristics and factors influencing hospital visits among children with nocturnal enuresis in Japan: The Hirakata-Urayasu population-based cohort study. Int J Urol 30(4):408-414. 2023

Oishi K, Inage E, Kojima M, Yamada H, Tanaka Y, Yoneyama T, Yamazaki S, Honjo A, Baba Y, Kudo T, Ohtsuka Y, Endo A, Nakabayashi Y, Oyama S, Shimizu T. Evidence of off-label inhalation therapy on pediatric asthma practice in Japan. Pediatr Int 65(1):e15595.2023

Oka I, Funayama R, Shimizu H, Takeuchi I, Nojiri S, Shimizu T, Arai K. Predictors of small bowel transit time for capsule endoscopy in children with inflammatory bowel disease. Pediatr Gastroenterol Hepatol Nutr 26(4):181-192.2023

Santosa I, Shoji H, Arai Y, Awata K, Tokita K, Shimizu T. Hepatic and skeletal muscle autophagy marker levels in rat models of prenatal and postnatal protein restriction. Nutrients 15(13):3058.2023

Sato S, Yamazaki S, Suzuki K, Kudo T, Ohtomo Y, Shimizu T. Cryptogenic organizing pneumonia in an infant. Pediatr Pulm 58(4):1275-1277. 2023

Takahashi N, Shoji H, Arai H, Tanaka K, Kakiuchi S, Yoda H, Shimizu T. Effect of biotin supplementation in infant formula: A multi-center study in Japan. Pediatr Int 65(1):e15359. 2023

Takeuchi I, Yanagi K, Takada S, Uchiyama T, Igarashi A, Motomura K, Hayashi Y, Nagano N, Matsuoka R, Sugiyama H, Yoshioka T, Saito H, Kawai T, Miyaji Y, Inuzuka Y, Matsubara Y, Ohya Y, Shimizu T, Matsumoto K, Arai K, Nomura I, Kaname T, Morita H. STAT6 gain-of-function variant exacerbates multiple allergic symptoms. J Allergy Clin Immunol 151(5):1402-1409.e6. 2023

Tanaka Y, Inage E, Matsumoto M, Murano Y, Endo A, Nakabayashi Y, Yokoya S, Iwama I, Suzuki Y, Oyama S, Baba Y, Kudo T, Ohtsuka Y, Shimizu T. Low billing rates for pediatric sedation fee on magnetic resonance imaging. Pediatr Int 65(1):e15532.2023

Tanimoto R, Ikuse T, Ito N, Sato H, Kasai Y, Yamada H, Saito N, Iwasaki T, Ikeno M, Suganuma H, Hisata K, Shoji H, Kudo T, Sakamoto K, Shimoji K, Kondo A, Shimizu T. A case of neonate with split cord malformation presenting with hypoplasia of the left lower extremity. Medicina (Kaunas) 59(4):726. 2023

Tokita K, Shoji H, Arai Y, Awata K, Santosa I, Murano Y, Shimizu T. Skeletal muscle insulin resistance in a novel fetal growth restriction model. Pediatr Rep 15(1):45-54. 2023

Yamada H, Kaitani A, Izawa K, Ando T, Kamei A, Uchida S, Maehara A, Kojima M, Yamamoto R, Wang H, Nagamine M, Maeda K, Uchida K, Nakano N, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T, Kitaura J. Staphylococcus aureus δ-toxin present on skin promotes the development of food allergy in a murine model. Front Immunol 14:1173069.2023

Yokoyama K, Yamamoto Y, Nambu R, Hagiwara SI, Abukawa D, Mizuochi T, Kudo T, Sado T, Iwata N, Ishige T, Iwama I, Kumagai H, Arai K, Shimizu T. Safety and efficacy of vedolizumab in pediatric patients with ulcerative colitis: multicenter study in Japan. J Gastroenterol Hepatol 38(7):1107-1115.2023

Arai N, Kudo T, Tokita K, Kyodo R, Sato M, Miyata E, Hosoi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Expression of oncogenic molecules in pediatric ulcerative colitis. Digestion 103(2):150-158. 2022

Awata K, Shoji H, Santosa I, Ikeda N, Murano Y, Ohkawa N, Nishizaki N, Hisata K, Kantake M, Obinata K, Shimizu T. Associations between size at birth and size at 6 years among preterm infants: a retrospective cohort study. Pediatr Int 64(1):e14844. 2022

Endo Y, Jimbo K, Arai N, Ochi T, Suzuki M, Yamataka A, Shimizu T. A pediatric case of inverted Meckel's diverticulum presenting with cyclic vomiting-like symptoms: A case report and literature review. Children 9:1817. 2022

Fukae T, Miyatsuka T, Himuro M, Wakabayashi Y, Iida H, Aoyama S, Mita T, Ikeda F, Haruna H, Takubo N, Nishida Y, Shimizu T, Watada H. Genetic ablation of p62/SQSTM1 demonstrates little effect on pancreatic ?-cell function under autophagy deficiency. Biochem Biophys Res Commun 612:99-104. 2022

Gonda Y, Ishii C, Mita M, Nishizaki N, Ohtomo Y, Hamase K, Shimizu T, Sasabe J. Astrocytic d-amino acid oxidase degrades d-serine in the hindbrain. FEBS Lett 596(22):2889-2897. 2022

Hayashi T, Murano Y, Muto Y, Takasu M、Sato H, Yagisawa H, Oshima K, Miyazaki N, Adachi T, Hisata K, Nakazawa T, Rahman M, Gilmour S, Shimizu T. Clinical features of children with COVID-19 in initial time of pandemic. Juntendo Medical Journal 68(6):622-626. 2022

Inage E, Tanaka Y, Matsui K, Yamada H, Kojima M, Toriumi S, Kudo T, Baba Y, Shimizu T. Gender disparities in the pediatric allergy-related guidelines in Japan. Pediatr Int 64(1):e14941. 2022

Kamei A, Izawa K, Ando T, Kaitani A, Yamamoto R, Maehara A, Ide T, Yamada H, Kojima M, Wang H, Tokushige K, Nakano N, Shimizu T, Ogawa H, Okumura K, Kitaura J. Development of mouse model for oral allergy syndrome to identify IgE cross-reactive pollen and food allergens: ragweed pollen cross-reacts with fennel and black pepper. Front Immunol 13:945222. 2022

Kasai Y, Komatsu M, Toyama Y, Nakano S, Hisata K, Niizuma T, Obinata K, Shimizu T. Characteristics and antimicrobial choice of pediatric bacterial enteritis in the Kanto region of Japan: A multicenter retrospective observational study. J Infect Chemother 28(6):723-728. 2022

Kashiwagi K, Jimbo K, Suzuki M, Arai N, Kudo T, Shimizu T. Impact of Anti-TNFα Treatment on the Humoral Response to the BNT162b2 mRNA COVID-19 Vaccine in Pediatric Inflammatory Bowel Disease Patients. Vaccines (Basel) 10(10):1618. 2022

Kim S, Suzuki M, Minowa K, Nittono H, Shimizu T. Efficacy of a Tibia Counter Rotator System for the Treatment of Internal Tibial Torsion in Children. Children (Basel) 9(7):970. 2022

Kudo T, Jimbo K, Shimizu H, Iwama I, Ishige T, Mizuochi T, Arai K, Kumagai H, Uchida K, Abukawa D, Shimizu T. Qing-Dai for pediatric ulcerative colitis multicenter survey and systematic review. Pediatr Int 64(1):e15113. 2022

Kumagai H, Shimizu T, Iwama I, Hagiwara SI, Kudo T, Takahashi M, Saito T, Kunisaki R, Uchino M, Hiraoka S, Naganuma M, Sugimoto K, Miyoshi J, Shibuya T, Hisamatsu T. A consensus statement on health-care transition for childhood-onset inflammatory bowel disease patients. Pediatr Int 64(1):e15241. 2022

Kyodo R, Takeuchi I, Narumi S, Shimizu H, Hata K, Yoshioka T, Tanase-Nakao K, Shimizu T, Arai K. Novel biallelic mutations in the DUOX2 gene underlying very early-onset inflammatory bowel disease: A case report. Clin Immunol 238:109015. 2022

Matsuda A, Nishizaki N, Abe H, Mizutani A, Niizuma T, Obinata K, Oguma K, Makino S, Ishitate M, Shimizu T. An infant of 26 weeks gestation with congenital miliary tuberculosis complicated by chronic lung disease requiring CPAP was diagnosed on Day 104 of life: congenital tuberculosis was confirmed by detection of calcified ovaries in his mother. Paediatr Int Child Health. 42(2):72-77. 2022

Miyata E, Jimbo K, Kyodo R, Suzuki M, Kudo T, Shimizu T. Differentiation of Yersinia enterocolitica enteritis from other bacterial enteritides by ultrasonography: A single-center case-control study. Pediatr Neonatol 63(3):262-268. 2022

Miyazaki M, Ohkawa N, Miyabayashi K, Shoji H, Takeichi T, Kantake M, Akiyama M, Shimizu T. Case of harlequin ichthyosis in preterm infant with a compound heterozygous ABCA12 missense mutation. J Dermatol 49(4):137-139. 2022

Mizutani A, Endo A, Saito M, Hara T, Nakagawa M, Sakuraya K, Murano Y, Nishizaki N, Hirano D, Fujinaga S, Ohtomo Y, Shimizu T. Hydrogen-rich water reduced oxidative stress and renal fibrosis in rats with unilateral ureteral obstruction. Pediatr Res 91(7):1695-1702. 2022

Morita M, Takeuchi I, Kato M, Migita O, Jimbo K, Shimizu H, Yoshimura S, Tomizawa D, Shimizu T, Hata K, Ishiguro A, Ari K. Intestinal outcome of bone marrow transplantation for monogenic inflammatory bowel disease. Pediatr Int 64(1):e14750. 2022

Nagata M, Sakaguchi K, Kusaba K, Tanaka Y, Shimizu T. A case of multisystem inflammatory syndrome in children with cardiogenic shock. Pediatr Int 64(1):e15304. 2022

Nishizaki N, Hirano D, Oishi K, Shimizu T. YouTube videos in Japanese as a source of information on nocturnal enuresis: a content-quality and reliability analysis. Pediatr Int 64(1):e15049. 2022

Nishizaki N, Obinata K, Shimizu T. Polymyxin B-Immobilized Fiber Column Direct Hemoperfusion for Micro-Preemie Infants: Is Extended Duration Better than Early Start?. Blood Purif 51(5):472-474. 2022

Oka I, Ohtomo Y, Shimizu T. Granulomatous vasculitis of the esophagus in a girl with odynophagia. Pediatr Int 64(1):e15253. 2022

Saito M, Nakazawa T, Toriumi S, Takasu M, Yagisawa H, Murano Y, Miyazaki N, Kurahashi H, Okumura A, Shimizu T. Case report: Mild encephalitis with a reversible splenial lesion associated with SARS-CoV-2 infection in a patient with MYRF variant. Front Pediatr 10:971432. 2022

Saitoh M, Endo A, Matsuda A, Miyano H, Gonda Y, Mizutani A, Hara T, Nakagawa M, Sakuraya S, Murano Y, Nishizaki N, Fujinaga S, Ohtomo Y, Shimizu T. The protective effects of hydrogen-rich water intake on renal injury in neonatal rats with high oxygen loading. Juntendo Medical Journal 68:235-241. 2022

Sakano M, Suzuki M, Nakano S, Noguchi A, Shimizu T. Alpha1-antitrypsin deficiency recognized by failure to gain weight in infancy. Pediatr Int 64(1):e14874. 2022

Santosa I, Shoji H, Awata K, Arai Y, Suganuma H, Shimizu T. Resistin in urine and breast milk: Relation to type of feeding and anthropometry at 1-month. Pediatr Rep 14(1):86-92. 2022

Santosa I, Shoji H, Itoh S, Shimizu T. Roles of probiotics in reduction of neonatal jaundice in term newborns. Juntendo Medical Journal 68(2):140-146. 2022

Sato M, Kudo T, Arai N, Kyodo R, Hosoi K, Sakaguchi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Evaluating Small Intestinal Motility in a Rat Model of Adolescent Irritable Bowel Syndrome. Juntendo Medical Journal 68(3):271-281. 2022

Shimizu H, Ebana R, Kudo T, Sato T, Hara T, Hosoi K, Usami M, Yoshida M, Takeuchi I, Nakase H, Iwama I, Arai K, Shimizu T. Both fecal calprotectin and fecal immunochemical tests are useful in children with inflammatory bowel disease. J Gastroenterol 57(5):344-356. 2022

Shoji H, Murano Y, Nojiri S, Arai Y, Awata K, Ikeda N, Ohkawa N, Nishizaki N, Suganuma H, Hisata K, Kantake M, Obinata K, Shimizu T. Growth trajectories during the first 6 years in survivors born at less than 25 weeks of gestation compared with those between 25 and 29 weeks. J Clin Med 11(5):1418. 2022

Shoji H, Murano Y, Saitoh Y, Ikeda N, Nishizaki N, Hisata K, kantake M, Obinata K, Yoneoka D, Shimizu T. Use of Head and Chest Circumference Ratio as an Index of Fetal Growth Retardation in Preterm Infants Nutrients 14(22):4942. 2022

Suzuki M, Noguchi A, Shimizu T. Response to 'AAT deficiency: PI*Mpalermo and PI*Siiyama, current diagnosis and future risk'. Pediatr Int 64(1):e15306. 2022

Toda M, Endo A, Hisata K, Kudo T, Shimizu T. Parechovirus infection in an infant with severe abdominal distention. Pediatr Int 64(1):e15075. 2022

Tokita K, Shimizu H, Takeuchi I, Shimizu T, Arai K. Long-term Efficacy and Safety of Golimumab for Ulcerative Colitis at a Pediatric Inflammatory Bowel Disease Center in Japan. Pediatr Gastroenterol Hepatol Nutr 25(6):461-472. 2022

Toyama Y, Hisata K, Kasai Y, Nakano S, Komatsu M, Shimizu T. Molecular epidemiology of meticillin-susceptible Staphylococcus aureus in the neonatal intensive care unit. J Hosp Infect 129:75-81. 2022

Yakabe A, Ikuse T, Ito N, Yamada H, Saito N, Kitamura Y, Iwasaki T, Ikeno M, Suganuma H, Abe S, Miyazaki N, Hisata K, Shoji H, Nakazawa T, Eguchi H, Shimizu T. A COL4A1 variant in a neonate with multiple intracranial hemorrhages and congenital cataracts. Hum Genome Var 9(1):24. 2022

Akimoto S, Fukunaga H, Akiya A, Hosono Y, Iso T, Shigemitsu S, Tanaka N, Tabuchi H, Hayashi H, Sekita G, Takahashi K, Shimizu T. Deep insight into cardiac dysfunction in children and young adults with Wolff-Parkinson-White syndrome using speckle tracking imaging. Heart Vessels 36(11):1712-1720. 2021

Ando K, Fujiya M, Watanabe K, Hiraoka S, Shiga H, Tanaka S, Iijima H, Mizushima T, Kobayashi T, Nagahori M, Ikeuchi H, Kato S, Torisu T, Kobayashi K, Higashiyama M, Fukui T, Kagaya T, Esaki M, Yanai S, Abukawa D, Naganuma M, Motoya S, Saruta M, Bamba S, Sasaki M, Uchiyama K, Fukuda K, Suzuki H, Nakase H, Shimizu T, Iizuka M, Watanabe M, Suzuki Y, Hisamatsu T. A nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan. J Gastroenterol 56(12):1062-1079. 2021

Aoyama N, Shimizu T. Approach to the seamless management of inflammatory bowel disease, considering special situations, shared decision-making, and disease burden. Digestion 102(1):12-17. 2021

Arai N, Kudo T, Tokita K, Kyodo R, Sato M, Miyata E, Hosoi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Effectiveness of biological agents in the treatment of pediatric patients with crohn's disease and anal fistulae. Digestion 102(5):783-788. 2021

Awata K, Shoji H, Santosa I, Naho I, Murano Y, Ohkawa N, Nishizaki N, Hisata K, Kantake M, Obinata K, Shimizu T. Associations between size at birth and size at 6 years among preterm infants: a retrospective cohort study. Pediatr Int 64(1):e14844. 2021

Baba Y, Matsuda A, Takaoka Y, Miyabayashi K, Yamada H, Yoneyama T, Yamazaki S, Inage E, Ohtsuka Y, Kantake M, Shimizu T. Role of IL-1RL1/ST2 infantile asthma. J Clin Cell Immunol 12:631-636. 2021

Croft NM, Faubion WA Jr, Kugathasan S, Kierkus J, Ruemmele FM, Shimizu T, Mostafa NM, Venetucci M, Finney-Hayward T, Sanchez Gonzalez Y, Bereswill M, Lazar A, Turner D. Efficacy and safety of adalimumab in paediatric patients with moderate-to-severe ulcerative colitis (ENVISION I): a randomised, controlled, phase 3 study. Lancet Gastroenterol Hepatol 6(8):616-627. 2021

Endo A, Haruna H, Takubo N, Shimizu T. The effectiveness of peer-assisted learning for medical students in pediatric bedside learning. Juntendo Medical Journal 67:367-372. 2021

Fukase S, Ando T, Matsuzawa M, Kimura M, Sone Y, Izawa K, Kaitani A, Kamei A, Kojima M, Nakano N, Maeda K, Shimizu T, Ogawa H, Okumura K, Nishiyama M, Murakami A, Ebihara N, Kitaura J. Pollen shells and soluble factors play non-redundant roles in the development of allergic conjunctivitis in mice. Ocul Surf 22:152-162. 2021

Hojo M, Nagahara A, Kudo T, Takeda T, Ikuse T, Matsumoto K, Ueda K, Ueyama H, Matsumoto K, Asaoka D, Shimizu T. Endoscopic findings of Helicobacter pylori gastritis in children and young adults based on the Kyoto classification of gastritis and age-associated changes. JGH Open 5(10):1197-1202. 2021

Horigome A, Hisata K, Odamaki T, Iwabuchi N, Xiao JZ, Shimizu T. Colonization of supplemented bifidobacterium breve M-16V in low birth weight infants and its effects on their gut microbiota weeks post-administration. Front Microbiol 12:610080. 2021

Ifuku M, Takahashi K, Hosono Y, Iso T, Ishikawa A, Haruna H, Takubo N, Komiya K, Kurita M, Ikeda F, Watada H, Shimizu T. Left atrial dysfunction and stiffness in pediatric and adult patients with type 1 diabetes mellitus assessed with speckle tracking echocardiography. Pediatr Diabetes 22(2):303-319. 2021

Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K. Features and outcomes of children with ulcerative colitis who undergo a diagnostic change: A single-center experience. Pediatr Gastroenterol Hepatol Nutr 24(4):357-365. 2021

Jimbo K, Okuno T, Ohgaki R, Nishikubo K, Kitamura Y, Sakurai Y, Quan L, Shoji H, Kanai Y, Shimizu T, Yokomizo T. Correction: A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy. PLoS One 16(2):e0247691. 2021

Kato M, Jimbo K, Nagata M, Endo Y, Kashiwagi K, Maruyama K, Ito N, Tokushima K, Arai N, Kyodo R, Sato M, Miyata E, Hosoi K, Inage E, Ikuse T, Fukunaga H, Kudo T, Shimizu T. Novel pediatric granulomatosis with polyangiitis with a marked bloody pericardial effusion and bloody stool: a case report. Allergy Asthma Clin Immunol 17(1):124. 2021

Kudo T, Abukawa D, Nakayama Y, Segawa O, Uchida K, Jimbo K, Shimizu T. Nationwide survey of pediatric gastrointestinal endoscopy in Japan. J Gastroenterol Hepatol 36(6):1545-1549. 2021

Kudo T, Arai K, Uchida K, Tajiri H, Hokari R, Suzuki Y, Shimizu T. Very early-onset inflammatory bowel disease in Japan: A nationwide survey. J Gastroenterol Hepatol 36(1):151-155. 2021

Kudo T, Fujii T, Maisawa SI, Sasaki M, Uchida K, Ida S, Kagimoto S, Yoden A, Shimizu T. A Multicenter Prospective Survey on Early-Onset Inflammatory Bowel Disease in Japan. Digestion 102(3):368-376. 2021

Kumagai H, Kudo T, Uchida K, Kunisaki R, Sugita A, Ohtsuka Y, Arai K, Kubota M, Tajiri H, Suzuki Y, Shimizu T. Transitional care for inflammatory bowel disease: A survey of Japanese pediatric gastroenterologists. Pediatr Int 63(1):65-71. 2021

Kumagai H, Suzuki Y, Shimizu T. Transitional care for patients with inflammatory bowel disease: Japanese experience. Digestion 102(1):18-24. 2021

Miura M, Shimizu H, Saito D, Miyoshi J, Matsuura M, Kudo T, Hirayama D, Yoshida M, Arai K, Iwama I, Nakase H, Shimizu T, Hisamatsu T. Multicenter, cross-sectional, observational study on Epstein-Barr viral infection status and thiopurine use by age group in patients with inflammatory bowel disease in Japan (EBISU study). J Gastroenterol 56(12):1080-1091. 2021

Miyata E, Kudo T, Ikuse T, Tokita K, Arai N, Oka I, KyodoR, Sato M, Hosoi K, Jimbo K, Aoyagi Y, Ohtsuka Y, Shimizu T. Eradication therapy forHelicobacter pyloriinfection based on the antimicrobial susceptibility test in children: A single-center study over 12 years. Helicobacter 26(1):e12764. 2021

Murano Y, Shoji H, Ikeda N, Okawa N, Hayashi K, Kantake M, Morisaki N, Shimizu T, Gilmour S. Analysis of factors associated with body mass index at ages 18 and 36 months among infants born extremely preterm. JAMA Netw Open 4(10):e2128555. 2021

Murano Y, Ueno R, Shi S, Kawashima T, Tanoue Y, Tanaka S, Nomura S, Shoji H, Shimizu T, Nguyen H, Miyata H, Gilmour S, Yoneoka D. Impact of domestic travel restrictions on transmission of COVID-19 infection using public transportation network approach. Sci Rep 11(1):3109. 2021

Niizuma T, Obinata K, Kinoshita K, Shimizu T. Pertussis transmission in a hospital office that was confirmed on the basis of loop-mediated isothermal amplification. Juntendo Medical Journal 67:355-359. 2021

Nishizaki N, Hara T, Obinata K, Shimizu T. Evaluating nocturnal polyuria in Japanese children with nocturnal enuresis. Pediatr Int 63(11):1339-1343. 2021

Nishizaki N, Shima T, Watanabe A, Obinata K, Shimizu T. Unsatisfactory short-term neurodevelopmental outcomes of preterm infants who received polymyxin B-immobilized fiber column-direct hemoperfusion for septic shock. Tohoku J Exp Med 253(4):275-281. 2021

Nishizaki N, Shimizu T. Is exchange transfusion for severe neonatal infection preferable to polymyxin B-immobilized fiber column for direct hemoperfusion: Pros and cons. Tohoku J Exp Med 254(2):141-142. 2021

Nishizaki N, Shimizu T. Definition of low nocturnal bladder capacity in Japanese enuretic children: Reply. Pediatr Int 63:1412. 2021

Osaka S, Nakano S, Mizuno T, Hiraoka Y, Minowa K, Hirai S, Mizutani A, Sabu Y, Miura Y, Shimizu T, Kusuhara H, Suzuki M, Hayashi H. A randomized trial to examine the impact of food on pharmacokinetics of 4-phenylbutyrate and change in amino acid availability after a single oral administration of sodium 4-phenylbutyrarte in healthy volunteers. Mol Genet Meta 132(4):220-226. 2021

Shimizu H, Arai K, Takeuchi I, Minowa K, Hosoi K, Sato M, Oka I, Kaburaki Y, Shimizu T. Long-term durability of infliximab for pediatric ulcerative colitis: A retrospective data review in a tertiary children's hospital in Japan. Pediatr Gastroenterol Hepatol Nutr 24(1):7-18. 2021

Suzuki M, Minowa K, Isayama H, Shimizu T. Acute Recurrent and Chronic Pancreatitis in Children. Pediatr Int 63(2):137-149. 2021

Yasudo H, Ando T, Maehara A, Ando T, Izawa K, Tanabe A, Kaitani A, Nomura S, Seki M, Yoshida K, Oda H, Okamoto Y, Wang H, Kamei A, Kojima M, Kimura M, Uchida K, Nakano N, Kaneko J, Ebihara N, Hasegawa K, Shimizu T, Takita J, Ogawa H, Okumura K, Ogawa S, Tamura N, Kitaura J. A possible association between a nucleotide-binding domain LRR-containing protein family PYD-containing protein 1 mutation and an autoinflammatory sisease involving liver cirrhosis. Hepatology 74(4):2296-2299. 2021

Yoneyama T, Nakano, N, Hara M, Yamada H, Izawa K, Uchida K, Kaitani A, Ando T, Kitaura J, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T. Notch signaling contributes to the establishment of sustained unresponsiveness to food allergens by oral immunotherapy. J Allergy Clin Immunol 147(3):1063-1076. 2021

Akimoto K, Harada M, Oda H, Furukawa T, Takahashi K, Kishiro M, Shimizu T, Nakanishi K, Kawasaki S, Amano A. Coronary Revascularization of Giant Aneurysms in Children With Kawasaki Disease: A Report of Two Cases. Front Pediatr 8:547369. 2020

Arai K, Kunisaki R, Kakuta F, Hagiwara S, Murakoshi T, Yanagi T, Shimizu T, Nakayama Y, Ishige T, Aomatsu T, Inoue M, Saito T, Iwama I, Kawashima H, Kumagai H, Tajiri H, Iwata N, Mochizuki T, Noguchi A, Kashiwabara T, Shimizu H, Suzuki Y, Hirano Y, Fujiwara T. Phenotypic characteristics of pediatric inflammatory bowel disease in Japan: results from a multicenter registry. Intestnial Research 18:412-420,2020

Ikuse T, Toda M, Kashiwagi K, Maruyama K, Nagata M, Tokushima K, Ito N, Tokita K, Kyodo R, Hosoi K, Jimbo K, Kudo T, Shimizu T. Efficacy of Helicobacter pylori Eradication Therapy on Platelet Recovery in Pediatric Immune Thrombocytopenic Purpura-Case Series and a Systematic Review. Microorganisms 8:1457. 2020

Izawa K, Kaitani A, Ando T, Maehara A, Nagamine M, Yamada H, Ando T, Ide T, Matsuzawa M, Okamoto Y, Yin E, Fukase S, Wang H, Kamei A, Uchida S, Keiko M, Nakano N, Uchida K, Tamura N, Ikeda K, Ebihara N, Shimizu T, Voehringer D, Roers A, Ogawa H, Okumura K, Kitaura J. Differential lipid recognition by mouse versus human CD300f, inhibiting passive cutaneous anaphylaxis, depends on a single amino acid substitution in its immunoglobulin-like domain. J Invest Dermatol 140:710-713,2020

Jimbo K, Okuno T, Ohgaki R, Nishikubo K, Kitamura Y, Sakurai Y, Quan L, Shoji H, Kanai Y, Shimizu T, Yokomizo T. A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy. PLoS One 15:e0241869. 2020

Kantake M, Ikeda N, Nakaoka H, Ohkawa N, Tanaka T, Miyabayashi K, Shoji H, Shimizu T. IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction. Clin Epigenetics 12:108,2020

Kashiwagi K, JimboK, Hosoi K, Miyano G, Kudo T, Yamataka A, Shimizu T. A novel segmental absence of intestinal musculature with small intestinal stenosis: a case report. BMC Gastroenterology 20:272,2020

Kato S, Shimizu T, Toyoda S, Gold BD, Ida S, Ishige T, Fujimura S, Kamiya S, Konno M, Kuwabara K, Ushijima K, Yoshimura N, Nakayama Y; Japanese Society for Pediatric Gastroenterology, Hepatology, Nutrition. The Updated JSPGHAN Guidelines for the management of helicobacter pylori infection in childhood. Pediatr Int 62:1315-1331. 2020

Kudo T, Fujii T, Maisawa SI, Sasaki M, Uchida K, Ida S, Kagimoto S, Yoden A, Shimizu T. A multicenter prospective survey on early-onset inflammatory bowel disease in Japan. Digestion 18:1-9,2020

Kyodo R, Kudo T, Horiuchi A, Sakamoto T, Shimizu T. Pureed diets containing a gelling agent to reduce the risk of aspiration in elderly patients with moderate to severe dysphagia: A randomized, crossover trial. Medicine (Baltimore) 99:e21165,2020

Matsumura S, Kurashima Y, Murasaki S, Morimoto M, Arai F, Saito Y, Katayama N, Kim D, Inagaki Y, Kudo T, Ernst PB, Shimizu T, Kiyono H. Stratified layer analysis reveals intrinsic leptin stimulates cryptal mesenchymal cells for controlling mucosal inflammation. Scientific Reports 10:18351. 2020

Mikami T, Sueyoshi R, Kosaka S, Yoshida S, Miyano G, Ochi T, Koga H, Okazaki T, Yanai T, Urao M, Lane G, Jimbo K, Suzuki K, Kuwatsuru R, Shimizu T, Yamataka A. Perforation in pediatric non-complicated appendicitis treated by antibiotics: the real incidence. Pediatr Surg Int 36:69-74,2020

Mizuno K, Shimizu T, Ida S, Ito S, Inokuchi M, Ohura T, Okumura A, Kawai M, Kikuchi T, Sakurai M, Sugihara S, Suzuki M, Takitani K, Tanaka D, Mushiake S, Yoshiike N, Kodama H, Okada K, Tsutsumi C, Hara M, Hanawa Y, Kawakami K, Inomata H, Oguni T, Bito Y, Uchida K, Sugiyama A. Policy statement of enteral nutrition for preterm and very low birthweight infants. Pediatr Int 62:124-127,2020

Niizuma T, Obinata K, Kinoshita K, Shimizu T. Diagnostic usefuluness of loop-mediated isothermal amplification for intrafamilial pertussis infection. Juntendo Medical Journal 66:233-237,2020

Nishizaki N, Hara T, Obinata K, Nakagawa M, Shimizu T. Clinical effects and outcomes after polymyxin B-immobilized fiber column direct hemoperfusion treatment for septic shock in preterm neonates. Pediatr Crit Care Med 21:156-163,2020

Nishizaki N, Hirano D, Shimizu T. Is urinary concentration important in desmopressin treatment for enuresis? Pediatr Int 62:1309-1310. 2020

Nishizaki N, Matsuda A, Yoneyama T, Watanabe A, Obinata K, Shimizu T. The influence on renal function of ibuprofen treatment for patent ductus arteriosus in extremely low birthweight infants. Pediatr Int 62:193-199,2020

Nishizaki, N., Ueno, R., Nagayama, Y, Abe H, Matsuda A, Mizutani A, Obinata K, Okazaki T, Shimizu T. Effects of continuous renal replacement therapy with the AN69ST membrane for septic shock and sepsis-induced AKI in an infant: a case report with literature review of cytokine/mediator removal therapy in children. Ren Replace Ther 2020;6;34. 2020

Sakamoto Y, Ishijima M, Nakano S, Suzuki M, Liu L, Tokita A, Kim SG, Shimizu T, Kaneko K, Nozawa M. Physiologic Leg Bowing is not a Physiologic Condition but Instead is Associated with Vitamin D Disorders in Toddlers. Calcif Tissue Int. 106:95-103,2020

Sato A, Suzuki T, Ikeno M, Takeda J, Yamamoto Y, Shinohara M, Makino S, Takeda S, Shimizu T, Itakura A. Pure 9p duplication syndrome with aplasia of the middle phalanges of the fifth fingers. Eur J Med Genet 63:104005,2020
Sato H, Nakao A, Sato K, Otomo Y, Niijima S, Shimizu T. Comparison of time to positivity of pediatric blood cultures obtained within the first year of life and in later years. J Infect Chemother 26:813-817,2020

Sato K, Kakiyama G, Suzuki M, Naritaka N, Takei H, Sato H, Kimura A, Murai T, Kurosawa T, Pandak WM, Nittono H, Shimizu T. Changes in conjugated urinary bile acids across age groups. Steroids 164:108730. 2020

Shoji H, Taka H, Kaga N, Ikeda N, Hisata K, Miura Y, Shimizu T. Choline-related metabolites influenced by feeding patterns in preterm and term infants. J Matern Fetal Neonatal Med 33:230-235. 2020

Shoji H, Watanabe A, Awaji A, Ikeda N, Hosozawa M, Ohkawa N, Nishizaki N, Hisata K, Kantake M, Obinata K, Shimizu T. Intrauterine growth restriction affects z-scores of anthropometric parameters during the first 6 years in very low-birth-weight-children born at less than 30 weeks of gestation. J Dev Orig Health Dis 11:44-48,2020

Suzuki M, Minowa K, Nakano S, Isayama H, Shimizu T. Genetic Abnormalities in Pancreatitis: An Update on Diagnosis, Clinical Features, and Treatment. Diagnostics (Basel). 11:E31. 2020

Takeuchi I, Kaburaki Y, Arai K, Shimizu H, Hirano Y, Nagata S, Shimizu T. Infliximab for very early-onset inflammatory bowel disease: A tertiary center experience in Japan. J Gastroenterol Hepatol 35:593-600,2020

Tsujiwaki A, Hisata K, Tohyama Y, Matsunaga N, Uehara Y, Sasaki T, Hiramatsu K, Shimizu T. Epidemiology of methicillin resistant staphylococcus aureus in a Japanese NICU. Pediatr Int 62:811-919,2020

Uchida S, Izawa K, Ando T, Yamada H, Uchida K, Negishi N, Kaitani A, Maehara A, Nagamine M, Kamei A, Takamori A, Maeda K, Nakano N, Shimizu T, Ogawa H, Okumura K, Nagahara A, Watanabe S, Kitaura J. CD300f is a potential therapeutic target for the treatment of food allergy. Allergy 75:471-474,2020

Yazaki K, Takahashi K, Kobayashi M, Yamada M, Iso T, Akimoto S, Shigemitsu S, Matsui K, Akimoto K, Kishiro M, Nakanishi K, Kawasaki S, Shimizu T. Exercise echocardiography demonstrates potential myocardial damage in patients with repaired tetralogy of Fallot using layer-specific strain analysis. Cardiol Young. 30:710-716,2020




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