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研究業績詳細

清水 俊明(シミズ トシアキ)

研究テーマ 新生児・小児の栄養・消化器病学
研究業績(論文) 教育実践上の主な業績
1.教育内容方法の工夫
2004年~現在 PCの使用により画像を多く取り入れた授業を行う
2004年~現在 学生からの授業評価に対するフィードバックを行う

2.作成した教科書、教材、参考書等
2005年5月 研修医のテキスト「研修医のための小児科診療500問」
2007年4月 小児科学のテキスト「小児科学・新生児学テキスト」
2007年4月 小児科医向けのテキスト「小児科診療ガイドライン」
2008年2月 学生用テキスト「講義録 小児科学」
2008年4月 小児科医向けのテキスト「小児科学」
2009年4月 小児科医向けのテキスト「小児科臨床ガイド」
2010年5月 小児科医向けのテキスト「小児科臨床ピクシス 下痢・便秘」
2011年1月 小児科医向けのテキスト「小児臨床栄養学」
2011年4月 小児科医向けのテキスト「小児科学」
2011年11月 小児科医向けのテキスト「子育て支援ハンドブック」
2012年1月 医師向けのテキスト「今日の治療指針」
2012年2月 小児科医向けのテキスト「今日の小児治療指針」
2012年2月 小児科医向けのテキスト「ビジュアル小児疾患診断のコツ」
2012年8月 小児科医向けのテキスト「小児生活習慣病ハンドブック」
2012年8月 小児科医向けのテキスト
       「最新ガイドライン準拠 小児科診断・治療指針」
2013年1月 小児科医向けのテキスト「臨床病態学 小児編」
2015年4月 小児科医向けテキスト「ネルソン小児科学」
2018年4月 小児科外来処方マニュアル
2019年2月 国際診療のための小児科アトラス辞典

3.教育方法・教育実践に関する発表、講演等
2003年~2017年 成田医学教育ワークショップにて卒前・卒後の教育方法などにつき世話人として討論

4.その他教育活動上特記すべき事項
2003年~2017年 医学部教務委員会 委員として活動(2011年、2017年に委員長)
2004年~現在  卒業支援委員会 委員として活動(2011年まで委員長)
2005年~2014年  大学院医学研究科基盤センター超微形態研究部門 運営委員長として活動
2005年~2017年 医学部カリキュラム委員会 委員として活動(2016年まで委員長)
2006年~2021年  医学部学生部委員会 委員として活動
2003年~2010年 医学部同窓会 学生会員理事として活動
2018年~2019年 医学部研究委員会委員長
2021年~現在 医学部教務委員会委員長

研究業績
原著
Arai N, Kudo T, Tokita K, Kyodo R, Sato M, Miyata E, Hosoi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Expression of oncogenic molecules in pediatric ulcerative colitis. Digestion 103(2):150-158. 2022

Fukae T, Miyatsuka T, Himuro M, Wakabayashi Y, Iida H, Aoyama S, Mita T, Ikeda F, Haruna H, Takubo N, Nishida Y, Shimizu T, Watada H. Genetic ablation of p62/SQSTM1 demonstrates little effect on pancreatic β-cell function under autophagy deficiency. Biochem Biophys Res Commun 612:99-104. 2022

Inage E, Tanaka Y, Matsui K, Yamada H, Kojima M, Toriumi S, Kudo T, Baba Y, Shimizu T. Gender disparities in the pediatric allergy-related guidelines in Japan. Pediatr Int 64(1):e14941. 2022

Kasai Y, Komatsu M, Toyama Y, Nakano S, Hisata K, Niizuma T, Obinata K, Shimizu T. Characteristics and antimicrobial choice of pediatric bacterial enteritis in the Kanto region of Japan: A multicenter retrospective observational study. J Infect Chemother 28(6):723-728. 2022

Kim S, Suzuki M, Minowa K, Nittono H, Shimizu T. Efficacy of a Tibia Counter Rotator System for the Treatment of Internal Tibial Torsion in Children. Children (Basel) 9(7):970. 2022

Kudo T, Jimbo K, Shimizu H, Iwama I, Ishige T, Mizuochi T, Arai K, Kumagai H, Uchida K, Abukawa D, Shimizu T. Qing-Dai for pediatric ulcerative colitis multicenter survey and systematic review. Pediatr Int 64(1):e15113. 2022

Kumagai H, Shimizu T, Iwama I, Hagiwara SI, Kudo T, Takahashi M, Saito T, Kunisaki R, Uchino M, Hiraoka S, Naganuma M, Sugimoto K, Miyoshi J, Shibuya T, Hisamatsu T. A consensus statement on health-care transition for childhood-onset inflammatory bowel disease patients. Pediatr Int 64(1):e15241. 2022

Kyodo R, Takeuchi I, Narumi S, Shimizu H, Hata K, Yoshioka T, Tanase-Nakao K, Shimizu T, Arai K. Novel biallelic mutations in the DUOX2 gene underlying very early-onset inflammatory bowel disease: A case report. Clin Immunol 238:109015. 2022

Matsuda A, Nishizaki N, Abe H, Mizutani A, Niizuma T, Obinata K, Oguma K, Makino S, Ishitate M, Shimizu T. An infant of 26 weeks gestation with congenital miliary tuberculosis complicated by chronic lung disease requiring CPAP was diagnosed on Day 104 of life: congenital tuberculosis was confirmed by detection of calcified ovaries in his mother. Paediatr Int Child Health 19:1-6. 2022

Miyata E, Jimbo K, Kyodo R, Suzuki M, Kudo T, Shimizu T. Differentiation of Yersinia enterocolitica enteritis from other bacterial enteritides by ultrasonography: A single-center case-control study. Pediatr Neonatol 63(3):262-268. 2022

Miyazaki M, Ohkawa N, Miyabayashi K, Shoji H, Takeichi T, Kantake M, Akiyama M, Shimizu T. Case of harlequin ichthyosis in preterm infant with a compound heterozygous ABCA12 missense mutation. J Dermatol 49(4):137-139. 2022

Mizutani A, Endo A, Saito M, Hara T, Nakagawa M, Sakuraya K, Murano Y, Nishizaki N, Hirano D, Fujinaga S, Ohtomo Y, Shimizu T. Hydrogen-rich water reduced oxidative stress and renal fibrosis in rats with unilateral ureteral obstruction. Pediatr Res 91(7):1695-1702. 2022

Morita M, Takeuchi I, Kato M, Migita O, Jimbo K, Shimizu H, Yoshimura S, Tomizawa D, Shimizu T, Hata K, Ishiguro A, Ari K. Intestinal outcome of bone marrow transplantation for monogenic inflammatory bowel disease. Pediatr Int 64(1):e14750. 2022

Nishizaki N, Hirano D, Oishi K, Shimizu T. YouTube videos in Japanese as a source of information on nocturnal enuresis: a content-quality and reliability analysis. Pediatr Int 64(1):e15049. 2022

Nishizaki N, Obinata K, Shimizu T. Polymyxin B-Immobilized Fiber Column Direct Hemoperfusion for Micro-Preemie Infants: Is Extended Duration Better than Early Start?. Blood Purif 51(5):472-474. 2022

Nishizaki N, Shimizu T. The developmental origins of health and chronic kidney disease: Current status and practices in Japan Pediatr Int 64(1):e15230. 2022

Sakano M, Suzuki M, Nakano S, Noguchi A, Shimizu T. Alpha1-antitrypsin deficiency recognized by failure to gain weight in infancy. Pediatr Int 64(1):e14874. 2022

Santosa I, Shoji H, Awata K, Arai Y, Suganuma H, Shimizu T. Resistin in urine and breast milk: Relation to type of feeding and anthropometry at 1-month. Pediatr Rep 14(1):86-92. 2022

Santosa I, Shoji H, Itoh S, Shimizu T. Roles of probiotics in reduction of neonatal jaundice in term newborns. Juntendo Mediacal Journal 68(2):140-146. 2022

Sato M, Kudo T, Arai N, Kyodo R, Hosoi K, Sakaguchi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Evaluating Small Intestinal Motility in a Rat Model of Adolescent Irritable Bowel Syndrome. Juntendo Medical Journal 68(3):271-281. 2022

Shimizu H, Ebana R, Kudo T, Sato T, Hara T, Hosoi K, Usami M, Yoshida M, Takeuchi I, Nakase H, Iwama I, Arai K, Shimizu T. Both fecal calprotectin and fecal immunochemical tests are useful in children with inflammatory bowel disease. J Gastroenterol 57(5):344-356. 2022

Shoji H, Murano Y, Nojiri S, Arai Y, Awata K, Ikeda N, Ohkawa N, Nishizaki N, Suganuma H, Hisata K, Kantake M, Obinata K, Shimizu T. Growth trajectories during the first 6 years in survivors born at less than 25 weeks of gestation compared with those between 25 and 29 weeks. J Clin Med 11(5):1418. 2022

Toda M, Endo A, Hisata K, Kudo T, Shimizu T. Parechovirus infection in an infant with severe abdominal distention. Pediatr Int 64(1):e15075. 2022

Yakabe A, Ikuse T, Ito N, Yamada H, Saito N, Kitamura Y, Iwasaki T, Ikeno M, Suganuma H, Abe S, Miyazaki N, Hisata K, Shoji H, Nakazawa T, Eguchi H, Shimizu T. A COL4A1 variant in a neonate with multiple intracranial hemorrhages and congenital cataracts. Hum Genome Var 9(1):24. 2022

Akimoto S, Fukunaga H, Akiya A, Hosono Y, Iso T, Shigemitsu S, Tanaka N, Tabuchi H, Hayashi H, Sekita G, Takahashi K, Shimizu T. Deep insight into cardiac dysfunction in children and young adults with Wolff-Parkinson-White syndrome using speckle tracking imaging. Heart Vessels 36(11):1712-1720. 2021

Ando K, Fujiya M, Watanabe K, Hiraoka S, Shiga H, Tanaka S, Iijima H, Mizushima T, Kobayashi T, Nagahori M, Ikeuchi H, Kato S, Torisu T, Kobayashi K, Higashiyama M, Fukui T, Kagaya T, Esaki M, Yanai S, Abukawa D, Naganuma M, Motoya S, Saruta M, Bamba S, Sasaki M, Uchiyama K, Fukuda K, Suzuki H, Nakase H, Shimizu T, Iizuka M, Watanabe M, Suzuki Y, Hisamatsu T. A nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan. J Gastroenterol 56(12):1062-1079. 2021

Aoyama N, Shimizu T. Approach to the seamless management of inflammatory bowel disease, considering special situations, shared decision-making, and disease burden. Digestion 102(1):12-17. 2021

Arai N, Kudo T, Tokita K, Kyodo R, Sato M, Miyata E, Hosoi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Effectiveness of biological agents in the treatment of pediatric patients with crohn's disease and anal fistulae. Digestion 102(5):783-788. 2021

Awata K, Shoji H, Santosa I, Naho I, Murano Y, Ohkawa N, Nishizaki N, Hisata K, Kantake M, Obinata K, Shimizu T. Associations between size at birth and size at 6 years among preterm infants: a retrospective cohort study. Pediatr Int 64(1):e14844. 2021

Baba Y, Matsuda A, Takaoka Y, Miyabayashi K, Yamada H, Yoneyama T, Yamazaki S, Inage E, Ohtsuka Y, Kantake M, Shimizu T. Role of IL-1RL1/ST2 infantile asthma. J Clin Cell Immunol 12:631-636. 2021

Croft NM, Faubion WA Jr, Kugathasan S, Kierkus J, Ruemmele FM, Shimizu T, Mostafa NM, Venetucci M, Finney-Hayward T, Sanchez Gonzalez Y, Bereswill M, Lazar A, Turner D. Efficacy and safety of adalimumab in paediatric patients with moderate-to-severe ulcerative colitis (ENVISION I): a randomised, controlled, phase 3 study. Lancet Gastroenterol Hepatol 6(8):616-627. 2021

Endo A, Haruna H, Takubo N, Shimizu T. The effectiveness of peer-assisted learning for medical students in pediatric bedside learning. Juntendo Medical Journal 67:367-372. 2021

Fukase S, Ando T, Matsuzawa M, Kimura M, Sone Y, Izawa K, Kaitani A, Kamei A, Kojima M, Nakano N, Maeda K, Shimizu T, Ogawa H, Okumura K, Nishiyama M, Murakami A, Ebihara N, Kitaura J. Pollen shells and soluble factors play non-redundant roles in the development of allergic conjunctivitis in mice. Ocul Surf 22:152-162. 2021

Hojo M, Nagahara A, Kudo T, Takeda T, Ikuse T, Matsumoto K, Ueda K, Ueyama H, Matsumoto K, Asaoka D, Shimizu T. Endoscopic findings of Helicobacter pylori gastritis in children and young adults based on the Kyoto classification of gastritis and age-associated changes. JGH Open 5(10):1197-1202. 2021

Horigome A, Hisata K, Odamaki T, Iwabuchi N, Xiao JZ, Shimizu T. Colonization of supplemented bifidobacterium breve M-16V in low birth weight infants and its effects on their gut microbiota weeks post-administration. Front Microbiol 12:610080. 2021

Ifuku M, Takahashi K, Hosono Y, Iso T, Ishikawa A, Haruna H, Takubo N, Komiya K, Kurita M, Ikeda F, Watada H, Shimizu T. Left atrial dysfunction and stiffness in pediatric and adult patients with type 1 diabetes mellitus assessed with speckle tracking echocardiography. Pediatr Diabetes 22(2):303-319. 2021

Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K. Features and outcomes of children with ulcerative colitis who undergo a diagnostic change: A single-center experience. Pediatr Gastroenterol Hepatol Nutr 24(4):357-365. 2021

Jimbo K, Okuno T, Ohgaki R, Nishikubo K, Kitamura Y, Sakurai Y, Quan L, Shoji H, Kanai Y, Shimizu T, Yokomizo T. Correction: A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy. PLoS One 16(2):e0247691. 2021

Kato M, Jimbo K, Nagata M, Endo Y, Kashiwagi K, Maruyama K, Ito N, Tokushima K, Arai N, Kyodo R, Sato M, Miyata E, Hosoi K, Inage E, Ikuse T, Fukunaga H, Kudo T, Shimizu T. Novel pediatric granulomatosis with polyangiitis with a marked bloody pericardial effusion and bloody stool: a case report. Allergy Asthma Clin Immunol 17(1):124. 2021

Kudo T, Abukawa D, Nakayama Y, Segawa O, Uchida K, Jimbo K, Shimizu T. Nationwide survey of pediatric gastrointestinal endoscopy in Japan. J Gastroenterol Hepatol 36(6):1545-1549. 2021

Kudo T, Arai K, Uchida K, Tajiri H, Hokari R, Suzuki Y, Shimizu T. Very early-onset inflammatory bowel disease in Japan: A nationwide survey. J Gastroenterol Hepatol 36(1):151-155. 2021

Kudo T, Fujii T, Maisawa SI, Sasaki M, Uchida K, Ida S, Kagimoto S, Yoden A, Shimizu T. A Multicenter Prospective Survey on Early-Onset Inflammatory Bowel Disease in Japan. Digestion 102(3):368-376. 2021

Kumagai H, Kudo T, Uchida K, Kunisaki R, Sugita A, Ohtsuka Y, Arai K, Kubota M, Tajiri H, Suzuki Y, Shimizu T. Transitional care for inflammatory bowel disease: A survey of Japanese pediatric gastroenterologists. Pediatr Int 63(1):65-71. 2021

Kumagai H, Suzuki Y, Shimizu T. Transitional care for patients with inflammatory bowel disease: Japanese experience. Digestion 102(1):18-24. 2021

Miura M, Shimizu H, Saito D, Miyoshi J, Matsuura M, Kudo T, Hirayama D, Yoshida M, Arai K, Iwama I, Nakase H, Shimizu T, Hisamatsu T. Multicenter, cross-sectional, observational study on Epstein-Barr viral infection status and thiopurine use by age group in patients with inflammatory bowel disease in Japan (EBISU study). J Gastroenterol 56(12):1080-1091. 2021

Miyata E, Kudo T, Ikuse T, Tokita K, Arai N, Oka I, KyodoR, Sato M, Hosoi K, Jimbo K, Aoyagi Y, Ohtsuka Y, Shimizu T. Eradication therapy forHelicobacter pyloriinfection based on the antimicrobial susceptibility test in children: A single-center study over 12 years. Helicobacter 26(1):e12764. 2021

Murano Y, Shoji H, Ikeda N, Okawa N, Hayashi K, Kantake M, Morisaki N, Shimizu T, Gilmour S. Analysis of factors associated with body mass index at ages 18 and 36 months among infants born extremely preterm. JAMA Netw Open 4(10):e2128555. 2021

Murano Y, Ueno R, Shi S, Kawashima T, Tanoue Y, Tanaka S, Nomura S, Shoji H, Shimizu T, Nguyen H, Miyata H, Gilmour S, Yoneoka D. Impact of domestic travel restrictions on transmission of COVID-19 infection using public transportation network approach. Sci Rep 11(1):3109. 2021

Niizuma T, Obinata K, Kinoshita K, Shimizu T. Pertussis transmission in a hospital office that was confirmed on the basis of loop-mediated isothermal amplification. Juntendo Medical Journal 67:355-359. 2021

Nishizaki N, Hara T, Obinata K, Shimizu T. Evaluating nocturnal polyuria in Japanese children with nocturnal enuresis. Pediatr Int 63(11):1339-1343. 2021

Nishizaki N, Shima T, Watanabe A, Obinata K, Shimizu T. Unsatisfactory short-term neurodevelopmental outcomes of preterm infants who received polymyxin B-immobilized fiber column-direct hemoperfusion for septic shock. Tohoku J Exp Med 253(4):275-281. 2021

Nishizaki N, Shimizu T. Is exchange transfusion for severe neonatal infection preferable to polymyxin B-immobilized fiber column for direct hemoperfusion: Pros and cons. Tohoku J Exp Med 254(2):141-142. 2021

Nishizaki N, Shimizu T. Definition of low nocturnal bladder capacity in Japanese enuretic children: Reply. Pediatr Int 63:1412. 2021

Osaka S, Nakano S, Mizuno T, Hiraoka Y, Minowa K, Hirai S, Mizutani A, Sabu Y, Miura Y, Shimizu T, Kusuhara H, Suzuki M, Hayashi H. A randomized trial to examine the impact of food on pharmacokinetics of 4-phenylbutyrate and change in amino acid availability after a single oral administration of sodium 4-phenylbutyrarte in healthy volunteers. Mol Genet Meta 132(4):220-226. 2021

Shimizu H, Arai K, Takeuchi I, Minowa K, Hosoi K, Sato M, Oka I, Kaburaki Y, Shimizu T. Long-term durability of infliximab for pediatric ulcerative colitis: A retrospective data review in a tertiary children's hospital in Japan. Pediatr Gastroenterol Hepatol Nutr 24(1):7-18. 2021

Suzuki M, Minowa K, Isayama H, Shimizu T. Acute Recurrent and Chronic Pancreatitis in Children. Pediatr Int 63(2):137-149. 2021

Yasudo H, Ando T, Maehara A, Ando T, Izawa K, Tanabe A, Kaitani A, Nomura S, Seki M, Yoshida K, Oda H, Okamoto Y, Wang H, Kamei A, Kojima M, Kimura M, Uchida K, Nakano N, Kaneko J, Ebihara N, Hasegawa K, Shimizu T, Takita J, Ogawa H, Okumura K, Ogawa S, Tamura N, Kitaura J. A possible association between a nucleotide-binding domain LRR-containing protein family PYD-containing protein 1 mutation and an autoinflammatory sisease involving liver cirrhosis. Hepatology 74(4):2296-2299. 2021

Yoneyama T, Nakano, N, Hara M, Yamada H, Izawa K, Uchida K, Kaitani A, Ando T, Kitaura J, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T. Notch signaling contributes to the establishment of sustained unresponsiveness to food allergens by oral immunotherapy. J Allergy Clin Immunol 147(3):1063-1076. 2021

Akimoto K, Harada M, Oda H, Furukawa T, Takahashi K, Kishiro M, Shimizu T, Nakanishi K, Kawasaki S, Amano A. Coronary Revascularization of Giant Aneurysms in Children With Kawasaki Disease: A Report of Two Cases. Front Pediatr 8:547369. 2020

Arai K, Kunisaki R, Kakuta F, Hagiwara S, Murakoshi T, Yanagi T, Shimizu T, Nakayama Y, Ishige T, Aomatsu T, Inoue M, Saito T, Iwama I, Kawashima H, Kumagai H, Tajiri H, Iwata N, Mochizuki T, Noguchi A, Kashiwabara T, Shimizu H, Suzuki Y, Hirano Y, Fujiwara T. Phenotypic characteristics of pediatric inflammatory bowel disease in Japan: results from a multicenter registry. Intestnial Research 18:412-420,2020

Ikuse T, Toda M, Kashiwagi K, Maruyama K, Nagata M, Tokushima K, Ito N, Tokita K, Kyodo R, Hosoi K, Jimbo K, Kudo T, Shimizu T. Efficacy of Helicobacter pylori Eradication Therapy on Platelet Recovery in Pediatric Immune Thrombocytopenic Purpura-Case Series and a Systematic Review. Microorganisms 8:1457. 2020

Izawa K, Kaitani A, Ando T, Maehara A, Nagamine M, Yamada H, Ando T, Ide T, Matsuzawa M, Okamoto Y, Yin E, Fukase S, Wang H, Kamei A, Uchida S, Keiko M, Nakano N, Uchida K, Tamura N, Ikeda K, Ebihara N, Shimizu T, Voehringer D, Roers A, Ogawa H, Okumura K, Kitaura J. Differential lipid recognition by mouse versus human CD300f, inhibiting passive cutaneous anaphylaxis, depends on a single amino acid substitution in its immunoglobulin-like domain. J Invest Dermatol 140:710-713,2020

Jimbo K, Okuno T, Ohgaki R, Nishikubo K, Kitamura Y, Sakurai Y, Quan L, Shoji H, Kanai Y, Shimizu T, Yokomizo T. A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy. PLoS One 15:e0241869. 2020

Kantake M, Ikeda N, Nakaoka H, Ohkawa N, Tanaka T, Miyabayashi K, Shoji H, Shimizu T. IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction. Clin Epigenetics 12:108,2020

Kashiwagi K, JimboK, Hosoi K, Miyano G, Kudo T, Yamataka A, Shimizu T. A novel segmental absence of intestinal musculature with small intestinal stenosis: a case report. BMC Gastroenterology 20:272,2020

Kato S, Shimizu T, Toyoda S, Gold BD, Ida S, Ishige T, Fujimura S, Kamiya S, Konno M, Kuwabara K, Ushijima K, Yoshimura N, Nakayama Y; Japanese Society for Pediatric Gastroenterology, Hepatology, Nutrition. The Updated JSPGHAN Guidelines for the management of helicobacter pylori infection in childhood. Pediatr Int 62:1315-1331. 2020

Kudo T, Fujii T, Maisawa SI, Sasaki M, Uchida K, Ida S, Kagimoto S, Yoden A, Shimizu T. A multicenter prospective survey on early-onset inflammatory bowel disease in Japan. Digestion 18:1-9,2020

Kyodo R, Kudo T, Horiuchi A, Sakamoto T, Shimizu T. Pureed diets containing a gelling agent to reduce the risk of aspiration in elderly patients with moderate to severe dysphagia: A randomized, crossover trial. Medicine (Baltimore) 99:e21165,2020

Matsumura S, Kurashima Y, Murasaki S, Morimoto M, Arai F, Saito Y, Katayama N, Kim D, Inagaki Y, Kudo T, Ernst PB, Shimizu T, Kiyono H. Stratified layer analysis reveals intrinsic leptin stimulates cryptal mesenchymal cells for controlling mucosal inflammation. Scientific Reports 10:18351. 2020

Mikami T, Sueyoshi R, Kosaka S, Yoshida S, Miyano G, Ochi T, Koga H, Okazaki T, Yanai T, Urao M, Lane G, Jimbo K, Suzuki K, Kuwatsuru R, Shimizu T, Yamataka A. Perforation in pediatric non-complicated appendicitis treated by antibiotics: the real incidence. Pediatr Surg Int 36:69-74,2020

Mizuno K, Shimizu T, Ida S, Ito S, Inokuchi M, Ohura T, Okumura A, Kawai M, Kikuchi T, Sakurai M, Sugihara S, Suzuki M, Takitani K, Tanaka D, Mushiake S, Yoshiike N, Kodama H, Okada K, Tsutsumi C, Hara M, Hanawa Y, Kawakami K, Inomata H, Oguni T, Bito Y, Uchida K, Sugiyama A. Policy statement of enteral nutrition for preterm and very low birthweight infants. Pediatr Int 62:124-127,2020

Niizuma T, Obinata K, Kinoshita K, Shimizu T. Diagnostic usefuluness of loop-mediated isothermal amplification for intrafamilial pertussis infection. Juntendo Medical Journal 66:233-237,2020

Nishizaki N, Hara T, Obinata K, Nakagawa M, Shimizu T. Clinical effects and outcomes after polymyxin B-immobilized fiber column direct hemoperfusion treatment for septic shock in preterm neonates. Pediatr Crit Care Med 21:156-163,2020

Nishizaki N, Hirano D, Shimizu T. Is urinary concentration important in desmopressin treatment for enuresis? Pediatr Int 62:1309-1310. 2020

Nishizaki N, Matsuda A, Yoneyama T, Watanabe A, Obinata K, Shimizu T. The influence on renal function of ibuprofen treatment for patent ductus arteriosus in extremely low birthweight infants. Pediatr Int 62:193-199,2020

Nishizaki, N., Ueno, R., Nagayama, Y, Abe H, Matsuda A, Mizutani A, Obinata K, Okazaki T, Shimizu T. Effects of continuous renal replacement therapy with the AN69ST membrane for septic shock and sepsis-induced AKI in an infant: a case report with literature review of cytokine/mediator removal therapy in children. Ren Replace Ther 2020;6;34. 2020

Sakamoto Y, Ishijima M, Nakano S, Suzuki M, Liu L, Tokita A, Kim SG, Shimizu T, Kaneko K, Nozawa M. Physiologic Leg Bowing is not a Physiologic Condition but Instead is Associated with Vitamin D Disorders in Toddlers. Calcif Tissue Int. 106:95-103,2020

Sato A, Suzuki T, Ikeno M, Takeda J, Yamamoto Y, Shinohara M, Makino S, Takeda S, Shimizu T, Itakura A. Pure 9p duplication syndrome with aplasia of the middle phalanges of the fifth fingers. Eur J Med Genet 63:104005,2020
Sato H, Nakao A, Sato K, Otomo Y, Niijima S, Shimizu T. Comparison of time to positivity of pediatric blood cultures obtained within the first year of life and in later years. J Infect Chemother 26:813-817,2020

Sato K, Kakiyama G, Suzuki M, Naritaka N, Takei H, Sato H, Kimura A, Murai T, Kurosawa T, Pandak WM, Nittono H, Shimizu T. Changes in conjugated urinary bile acids across age groups. Steroids 164:108730. 2020

Shoji H, Taka H, Kaga N, Ikeda N, Hisata K, Miura Y, Shimizu T. Choline-related metabolites influenced by feeding patterns in preterm and term infants. J Matern Fetal Neonatal Med 33:230-235. 2020

Shoji H, Watanabe A, Awaji A, Ikeda N, Hosozawa M, Ohkawa N, Nishizaki N, Hisata K, Kantake M, Obinata K, Shimizu T. Intrauterine growth restriction affects z-scores of anthropometric parameters during the first 6 years in very low-birth-weight-children born at less than 30 weeks of gestation. J Dev Orig Health Dis 11:44-48,2020

Suzuki M, Minowa K, Nakano S, Isayama H, Shimizu T. Genetic Abnormalities in Pancreatitis: An Update on Diagnosis, Clinical Features, and Treatment. Diagnostics (Basel). 11:E31. 2020

Takeuchi I, Kaburaki Y, Arai K, Shimizu H, Hirano Y, Nagata S, Shimizu T. Infliximab for very early-onset inflammatory bowel disease: A tertiary center experience in Japan. J Gastroenterol Hepatol 35:593-600,2020

Tsujiwaki A, Hisata K, Tohyama Y, Matsunaga N, Uehara Y, Sasaki T, Hiramatsu K, Shimizu T. Epidemiology of methicillin resistant staphylococcus aureus in a Japanese NICU. Pediatr Int 62:811-919,2020

Uchida S, Izawa K, Ando T, Yamada H, Uchida K, Negishi N, Kaitani A, Maehara A, Nagamine M, Kamei A, Takamori A, Maeda K, Nakano N, Shimizu T, Ogawa H, Okumura K, Nagahara A, Watanabe S, Kitaura J. CD300f is a potential therapeutic target for the treatment of food allergy. Allergy 75:471-474,2020

Yazaki K, Takahashi K, Kobayashi M, Yamada M, Iso T, Akimoto S, Shigemitsu S, Matsui K, Akimoto K, Kishiro M, Nakanishi K, Kawasaki S, Shimizu T. Exercise echocardiography demonstrates potential myocardial damage in patients with repaired tetralogy of Fallot using layer-specific strain analysis. Cardiol Young. 30:710-716,2020

Andica C, Hagiwara A, Hori M, Kamagata K, Koshino S, Maekawa T, Suzuki M, Fujiwara H, Ikeno M, Shimizu T, Suzuki H, Sugano H, Arai H, Aoki S. Review of synthetic MRI in pediatric brains: Basic principle of MR quantification, its features, clinical applications, and limitations. J Neuroradiol 46:268-275,2019

Hagiwara SI, Kudo T, Kakuta F, Inoue M, Yokoyama K, Umetsu S, Iwama I, Yodoshi T, Tatsuki M, Shimizu T, Nakayama Y. Clinical Safety and Utility of Pediatric Balloon Assisted Enteroscopy; A Multicenter Prospective Study in Japan. J Pediatr Gastroenterol Nutr 68:306-310,2019

Hatta K, Hosozawa M, Tanaka K, Shimizu T. Exploring traits of autism and their impact on functional disability in children with somatic symptom disorder. J Autism Dev Disord 49:729-737,2019

Iso M, Suzuki M, Yanagi K, Minowa K, Sakurai Y, Nakano S, Satou K, Shimizu T, Kaname T. The CFTR gene variants in Japanese children with idiopathic pancreatitis. Hum Genome Var 6:17. 2019

Iso T, Takahashi K, Yazaki K, Ifuku M, Nii M, Fukae T, Yazawa R, Ishikawa A, Haruna H, Takubo N, Kurita M, Ikeda F, Watada H, Shimizu T. In-depth insight into the mechanisms of cardiac dysfunction in patients with type 1 diabetes mellitus using layer-specific strain analysis. Circ J 83:1330-1337,2019

Jimbo K, Ohtsuka Y, Kono T, Arai N, Kyoudo R, Hosoi K, Aoyagi Y, Kudo T, Asai N, Shimizu T. Ultrasonographic study of intestinal Doppler blood flow in infantile non-IgE-mediated gastrointestinal food allergy. Allergol Int 68:199-206,2019

Kumagai H, Kudo T, Uchida K, Kunisaki R, Sugita A, Ohtsuka Y, Arai K, Kubota M, Tajiri H, Suzuki Y, Shimizu T. Adult gastroenterologists' views on transitional care: Results from a survey. Pediatr Int 61:817-822. 2019

Matsuda A, Fukunaga H, Tobayama H, Nakanishi K, Furukawa T, Takahashi K, Otomo Y, Kawasaki S, Shimizu T, Niijima S. Acute heart failure due to idiopathic rupture of the mitral valve chordae tendineae in an infant. Juntendo Medical Journal 65:286-291. 2019

Mayumi R, Murano Y, Yokota R, Nakao A, Miyazaki N, Hara T, Mizutani A, Hayashi K, Sakurai Y, Shoji H, Nakazawa T, Shimizu T. Urinary angiotensinogen in patients with urinary tract infection. Pediatr Int 61:712-714. 2019

Mizutani A, Fujinaga S, Sakuraya K, Hirano D, Shimizu T. Positive effects of single-daily high-dose mizoribine therapy after cyclophosphamide in young children with steroid-dependent nephrotic syndrome. Clin Exp Nephrol 23:244-250,2019

Nakano S, Osaka S, Sabu Y, Minowa K, Hirai S, Kondou H, Kimura T, Azuma Y, Watanabe S, Inui A, Bessho K, Nakamura H, Kusano H, Nakazawa A, Tanikawa K, Kage M, Shimizu T, Kusuhara H, Zen Y, Suzuki M, Hayashi H. Effect of food on the pharmacokinetics and therapeutic efficacy of 4-phenylbutyrate in progressive familial intrahepatic cholestasis. Sci Rep 9:17075. 2019

Nakano S, Suzuki M, Haruna H, Yamataka A, Shimizu T. Gallstone formation due to rapid weight loss through hyperthyroidism. J Pediatr Endocrinol Metab 32:1395-1398. 2019

Nakao A, Hisata K, Fujimori M, Matsunaga N, Komatsu M, Shimizu T. Amoxicillin effect on bacterial load in group A streptococcal pharyngitis: comparison of single and multiple daily dosage regimens. BMC Pediatr 19:205,2019

Naritaka N, Suzuki M, Takei H, Chen HL, Oh SH, Kaewplang P, Zhang C, Murai T, Kurosawa T, Kimura A, Shimizu T, Nittono H. Use of dried urine spots for screening of inborn errors of bile acid synthesis. Pediatr Int 61:489-449,2019

Nishizaki N, Obinata K, Kantake M, Yoshida N, Ohtomo Y, Niijima S, Yanagisawa N, Nishizaki Y, Shoji H, Shimizu T. Association between the frequency of bedwetting and late preterm birth in children aged ≥5 years. Acta Paediatr 108:282-287,2019

Ochi T, Ishiyama A, Yazaki Y, Murakami H, Takeda M, Seo S, Sueyoshi R, Lane GJ, Haruna H, Shimizu T, Yamataka A. Surgical management of hypospadias in cases with concomitant disorders of sex development. Pediatr Surg Int 35:611-617,2019

Shigemitsu S, Takahashi K, Yazaki K, Kobayashi M, Yamada M, Akimoto K, Tamaichi H, Fujimura J, Saito M, Nii M, Itatani K, Shimizu T. New insight into the intraventricular pressure gradient as a sensitive indicator of diastolic cardiac dysfunction in patients with childhood cancer after anthracycline therapy. Heart Vessels 34:992-1001,2019

Shima T, Okumura A, Kurahashi H, Numoto S, Abe S, Ikeno M, Shimizu T; Norovirus-associated Encephalitis/Encephalopathy Collaborative Study investigators. A nationwide survey of norovirus-associated encephalitis/encephalopathy in Japan. Brain Dev 41:263-270,2019

Shimizu T, Nakayama Y, Ishii E, Ida S, Satou T, Tokuhara D, Arai K, Nii M, Rydholm H, Yajima T; J-NEPECS (Japan Nexium Pediatrics Study) Group. Oral esomeprazole in Japanese pediatric patients with gastric acid-related disease: Safety, efficacy, and pharmacokinetics. Pediatr Int 61:87-95,2019

Shimizu Y, Yanobu-Takanashi R, Nakano K, Hamase K, Shimizu T, Okamura T. A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats. Mamm Genome 30:23-33,2019

Shoji H, Shimizu T. Effect of human breast milk on biological metabolism in infants. Pediatr Int 61:6-15,2019
Suzuki M, Shimizu T. Is SPINK1 gene mutation associated with development of pancreatic cancer? New insight from a large retrospective study. EBioMedicine. 50:5-6. 2019

Takahashi K, Nii M, Takigiku K, Toyono M, Iwashima S, Inoue N, Tanaka N, Matsui K, Shigemitsu S, Yamada M, Kobayashi M, Yazaki K, Itatani K, Shimizu T. Development of suction force during early diastole from the left atrium to the left ventricle in infants, children, and adolescents. Heart Vessels 34:296-306,2019

Takahashi M, Izawa K, Urai M, Yamanishi Y, Maehara A, Isobe M, Matsukawa T, Kaitani A, Takamori A, Uchida S, Yamada H, Nagamine M, Ando T, Shimizu T, Ogawa H, Okumura K, Kinjo Y, Kitamura T, Kitaura J. The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide-dependent neutrophil recruitment. Sci Signal 12:(564),2019

Takamori A, Izawa K, Kaitani A, Ando T, Okamoto Y, Maehara A, Tanabe A, Nagamine M, Yamada H, Uchida S, Uchida K, Isobe M, Hatayama T, Watanabe D, Ando T, Ide T, Matsuzawa M, Maeda K, Nakano N, Tamura N, Ikeda K, Ebihara N, Shimizu T, Ogawa H, Okumura K, Kitaura J. Identification of inhibitory mechanisms in pseudo-allergy involving Mrgprb2/MRGPRX2-mediated mast cell activation. J Allergy Clin Immunol 143:1231-1235,2019

Toda K, Hisata K, Satoh T, Katsumata N, Odamaki T, Mitsuyama E, Katayama T, Kuhara T, Aisaka K, Shimizu T, Xiao JZ. Neonatal oral fluid as a transmission route for bifidobacteria to the infant gut immediately after birth. Sci Rep 9:8692,2019

Tsukada I, Shimada S, Shono T, Nishizaki N, Oda H, Suzuki K, Niizuma T, Obinata K, Yamamoto T, Shimizu T. PRRT2 mutation in a sporadic case of paroxysmal kinesigenic dyskinesia. Juntendo Medical Journal 65:95-98,2019

Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Isihige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T. Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan. Intest Res 17:476-485. 2019

Yazawa R, Nishida Y, Aoyama S, Tanida I, Miyatsuka T, Suzuki L, Himuro M, Haruna H, Takubo N, Shimizu T, Watada H. Establishment of a system for screening autophagic flux regulators using a modified fluorescent reporter and CRISPR/Cas9. Biochem Biophys Res Commun 516:686-692,2019

Yoshida N, Arai Y, Kasai Y, Ohtomo Y, Niijima S, Shimizu T. West syndrome associated with glycogen storage disease type 1b. Epilepsy & Seizure 11:46-51. 2019




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