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研究業績詳細

齋田良知（サイタヨシトモ）

研究テーマ	細胞治療　膝関節外科　骨代謝学　スポーツ医学　スポーツ外傷
研究業績（論文）	1. Ishikawa S, Arase N, Suenaga T, Saita Y, Noda M, Kuriyama T, Arase H, Saito T. Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). Int Immunol. 16:1019-25. 2004 2. Saita Y, Takagi T, Kitahara K, Usui M, Miyazono K, Ezura Y, Nakashima K, Kurosawa H, Ishii S, Noda M. Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia. J Biol Chem. 282:12907-15. 2007, 3. Kato N, Hasegawa U, Morimoto N, Saita Y, Nakashima K, Ezura Y, Kurosawa H, Akiyoshi K, Noda M. Nanogel-based delivery system enhances PGE2 effects on bone formation. J Cell Biochem.101:1063-70. 2007, 4. Saita Y, Nakamura T, Mizoguchi F, Nakashima K, Hemmi H, Hayata T, Ezura Y, Kurosawa H, Kato S, Noda M. Combinatory effects of androgen receptor deficiency and hind limb unloading on bone. Horm Metab Res. 41:822-8. 2009, 5. Hayashi C, Hasegawa U, Saita Y, Hemmi H, Hayata T, Nakashima K, Ezura Y, Amagasa T, Akiyoshi K, Noda M. Osteoblastic bone formation is induced by using nanogel-crosslinking hydrogel as novel scaffold for bone growth factor. J Cell Physiol.220:1-7.2009, 6. Liu L, Ishijima M, Futami I, Kaneko H, Kubota M, Kawasaki T, Matsumoto T, Kurihara H, Ning L, Xu Z, Ikeda H, Takazawa Y, Saita Y, Kimura Y, Xu S, Kaneko K, Kurosawa H. Correlation between synovitis detected on enhanced-magnetic resonance imaging and a histological analysis with a patient-oriented outcome measure for Japanese patients with end-stage knee osteoarthritis receiving joint replacement surgery. Clin Rheumatol. 29:1185-90. 2010, 7. Kubota M, Ishijima M, Kurosawa H, Liu L, Ikeda H, Osawa A, Takazawa Y, Kawasaki T, Saita Y, Kimura Y, Kaneko K. A longitudinal study of the relationship between the status of bone marrow abnormalities and progression of knee osteoarthritis. J Orthop Sci. 15:641-6. 2010, 8. Nagao M, Saita Y, Hanyu R, Hemmi H, Notomi T, Hayata T, Nakamoto T, Nakashima K, Kaneko K, Kurosawa H, Ishii S, Ezura Y, Noda M. Schnurri-2 deficiency counteracts against bone loss induced by ovariectomy. J Cell Physiol. 226:573-8. 2011, 9. Hanyu R, Hayata T, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Knonenbery H, Kaneko K, Kurosawa H, Ezura Y, Noda M. Per-1 is a specific clock gene regulated by parathyroid hormone (PTH) signaling in osteoblasts and is functional for the transcriptional events induced by PTH. J Cell Biochem. 112:433-8. 2011, 10. Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, Karsenty G, Denhardt DT, Vilardaga JP, Noda M. Sympathetic control of bone mass regulated by osteopontin. Proc Natl Acad Sci U S A. 108:17767-72. 2011, 11. Nojiri H, Saita Y, Morikawa D, Kobayashi K, Tsuda C, Miyazaki T, Saito M, Marumo K, Yonezawa I, Kaneko K, Shirasawa T, Shimizu T. Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking. J Bone Miner Res. 26:2682-94. 2011, 12. Hanyu R, Wehbi VL, Hayata T, Moriya S, Feinstein TN, Ezura Y, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Takeda S, Kaneko K, Kurosawa H, Karsenty G, Kronenberg HM, Vilardaga JP, Noda M. Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proc Natl Acad Sci U S A. 109:7433-8 2012, 13. Nagao M, Saita Y, Kameda S, Seto H, Sadatsuki R, Takazawa Y, Yoshimura M, Aoba Y, Ikeda H, Kaneko K, Nozawa M, Kim SG. Headless compression screw fixation of jones fractures: an outcomes study in Japanese athletes. Am J Sports Med. 40:2578-82. 2012, 14. Kaneko H, Ishijima M, Doi T, Futami I, Liu L, Sadatsuki R, Yusup A, Hada S, Kubota M, Kawasaki T, Saita Y, Takazawa Y, Ikeda H, Kurosawa H, Kaneko K. Reference intervals of serum hyaluronic acid corresponding to the radiographic severity of knee osteoarthritis in women. BMC Musculoskelet Disord. 18;14:34. 2013, 15. Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T. Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading. J Bone Miner Res. 28:2368-80. 2013, 16. Liu L, Ishijima M, Kaneko H, Futami I, Sadatsuki R, Hada S, Yusup A, Shimura Y, Kubota M, Saita Y, Takazawa Y, Ikeda H, Kurosawa H, Kaneko K. Disability for daily living is a predictor for joint replacement in patients with end-stage knee osteoarthritis. J Bone Miner Metab. 32:192-9. 2014, 17. Takazawa Y, Ikeda H, Ishijima M, Kubota M, Saita Y, Kaneko H, Kobayashi Y, Sadatsuki R, Hada S, Kaneko K. Reconstruction of a ruptured patellar tendon using ipsilateral semitendinosus and gracilis tendons with preserved distal insertions: two case reports. BMC Res Notes. 6:361. 2013, 18. Saita Y, Ishijima M, Mogami A, Kubota M, Baba T, Kaketa T, Nagao M, Sakamoto Y, Sakai K, Kato R, Nagura N, Miyagawa K, Wada T, Liu L, Obayashi O, Shitoto K, Nozawa M, Kajihara H, Gen H, Kaneko K. The fracture sites of atypical femoral fractures are associated with the weight-bearing lower limb alignment. Bone. 66:105-10. 2014, 19. Hada S, Kaneko H, Sadatsuki R, Liu L, Futami I, Kinoshita M, Yusup A, Saita Y, Takazawa Y, Ikeda H, Kaneko K, Ishijima M. The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis: a cross-sectional study. Osteoarthritis Cartilage. 22:1583-9. 2014, 20. Saita Y, Ishijima M, Mogami A, Kubota M, Baba T, Kaketa T, Nagao M, Sakamoto Y, Sakai K, Homma Y, Kato R, Nagura N, Miyagawa K, Wada T, Liu L, Matsuoka J, Obayashi O, Shitoto K, Nozawa M, Kajihara H, Gen H, Kaneko K. The incidence of and risk factors for developing atypical femoral fractures in Japan. J Bone Miner Metab. 33:311-8. 2015, 21. Nagao M, Doi T, Saita Y, Kobayashi Y, Kubota M, Kaneko H, Takazawa Y, Ishijima M, Kurosawa H, Kaneko K, Nozawa M, Ikeda H, Kim SG. A novel patient-reported outcome measure for anterior cruciate ligament injury: evaluating the reliability, validity, and responsiveness of Japanese anterior cruciate ligament questionnaire 25. Knee Surg Sports Traumatol Arthrosc. 2015 24(9):2973-2982, 22. Yusup A, Kaneko H, Liu L, Ning L, Sadatsuki R, Hada S, Kamagata K, Kinoshita M, Futami I, Shimura Y, Tsuchiya M, Saita Y, Takazawa Y, Ikeda H, Aoki S, Kaneko K, Ishijima M. Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee osteoarthritis: a cross-sectional study. Osteoarthritis Cartilage. 23(11):1858-1864. 2015, 23. Takazawa Y, Ikeda H, Saita Y, Ishijima M, Nagayama M, Kaneko H, Kobayashi Y, Hada S, Sadatsuki R, Kaneko K. Case series: Revision anterior cruciate ligament reconstructions using patellar tendon autografts. Knee. pii: S0968-0160(15)00139-8. 2015, 24. Kobayashi K, Nojiri H, Saita Y, Morikawa D, Ozawa Y, Watanabe K, Koike M, Asou Y, Shirasawa T, Yokote K, Kaneko K, Shimizu T. Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis. Sci Rep.5:9148. 2015, 25. Wakayama T, Saita Y, Baba T, Nojiri H, Kaneko K Pathological Relationship of Osteomalacia at the Site of Atypical Periprosthetic Femoral Shaft Fracture after Typical Femoral Neck Fracture Occurred in the Patient with Rheumatoid Arthritis: A Case Report J Rheum Dis Treat 2015, 26. Koike M, Nojiri H, Ozawa Y, Watanabe K, Muramatsu Y, Kaneko H, Morikawa D, Kobayashi K, Saita Y, Sasho T, Shirasawa T, Yokote K, Kaneko K, Shimizu T. Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration. Sci Rep.5:11722 2015, 27. Takazawa Y, Nagayama M, Ikeda H, Kawasaki T, Ishijima M, Saita Y, Kaneko H, Kobayashi Y, Hada S, Kaneko K. Anterior cruciate ligament injuries in elite and high school rugby players: a 11-year review. Phys Sportsmed.44:53-8. 2016, 28. Saita Y, Ishijima M, Kaneko K. Atypical femoral fractures and bisphosphonate use: current evidence and clinical implications. Ther Adv Chronic Dis. 6:185-93. Review. 2015, 29. Saita Y, Ikeda H, Kaneko K. Differences Between Sports Medicine in Europe and Japan. Juntendo Medical Journal 64 Page11-16 2018 30. Shimasaki Y, Nagao M, Miyamori T, Aoba Y, Fukushi N, Saita Y, Ikeda H, Kim SG, Nozawa M, Kaneko K, Yoshimura M. Evaluating the Risk of a Fifth Metatarsal Stress Fracture by Measuring the Serum 25-Hydroxyvitamin D Levels. Foot Ankle Int. 37:307-11. 2016, 31. Kubota M, Ikeda H, Takazawa Y, Ishijima M, Saita Y, Kaneko H, Kim SG, Kurosawa H, Kaneko K Preoperative assessments completed for anterior cruciate ligament reconstructions with remnant preservation. J Orthop. 14:S75-8. 2015, 32. Kobayashi Y, Saita Y, Nishio H, Ikeda H, Takazawa Y, Nagao M, Takaku T, Komatsu N, Kaneko K. Leukocyte concentration and composition in platelet-rich plasma (PRP) influences the growth factor and protease concentrations. J Orthop Sci. 21:683-9. 2016, 33. Takazawa Y, Ikeda H, Saita Y, Kawasaki T, Ishijima M, Nagayama M, Kaneko H, Kaneko K. Return to Play of Rugby Players After Anterior Cruciate Ligament Reconstruction Using Hamstring Autograft: Return to Sports and Graft Failure According to Age. Arthroscopy. 33:181-189. 2017, 34. Yoshida K, Itoigawa Y, Maruyama Y, Saita Y, Takazawa Y, Ikeda H, Kaneko K, Sakai T, Okuwaki T. Application of shear wave elastography for the gastrocnemius medial head to tennis leg. Clin Anat. 30:114-119. 2017, 35. Saita Y, Nagao M, Kawasaki T, Kobayashi Y, Kobayashi K, Nakajima H, Takazawa Y, Kaneko K, Ikeda H. Range limitation in hip internal rotation and fifth metatarsal stress fractures (Jones fracture) in professional football players. Knee Surg Sports Traumatol Arthrosc. 2018 26(7):1943-1949. 36. Mid and long term outcomes after fixation of osteochondritis dissecans Kubota M, Ishijima M, Ikeda H, Takazawa Y, Saita Y, Kaneko H, Kurosawa H, Kaneko K J Orthop. 2018 15: 536-539. 37. Saita Y, Schoenhuber H, Thiébat G, Ravasio G, Pozzoni R, Panzeri A, Galli M, Nagao M, Takazawa Y, Ikeda H, Kaneko K. Knee hyperextension and a small lateral condyle are associated with greater quantified antero-lateral rotatory instability in the patients with a complete anterior cruciate ligament (ACL) rupture. Knee Surg Sports Traumatol Arthrosc. 27(3):868-874. 2019 38. Miyamori T, Nagao M, Sawa R, Tumilty S, Yoshimura M, Saita Y, Ikeda H, Kaneko K.Playing football on artificial turf as a risk factor for fifth metatarsal stress fracture: a retrospective cohort study. BMJ Open. 9:e022864. 2019 39. Nishio H, Saita Y, Kobayashi Y, Takaku T, Fukusato S, Uchino S, Wakayama T, Ikeda H, Kaneko K. Platelet-rich plasma promotes recruitment of macrophages in the process of tendon healing. Regen Ther. 2020 14:262-270. 40. Huang H, Nagao M, Arita H, Nishio H, Kaneko H, Saita Y, Ishijima M, Takazawa Y, Ikeda H, Kaneko K. Validation and defining the minimal clinically important difference of the Japanese version of the IKDC Subjective Knee Form. J Orthop Sci. 2020 Online ahead of print. 41. Huang H, Nagao M, Arita H, Shiozawa J, Nishio H, Kobayashi Y, Kaneko H, Nagayama M, Saita Y, Ishijima M, Takazawa Y, Ikeda H, Kaneko K. Reproducibility, responsiveness and validation of the Tampa Scale for Kinesiophobia in patients with ACL injuries. Health Qual Life Outcomes. 2019 17(1):150. 42. Araya N, Miyatake K, Tsuji K, Katagiri H, Nakagawa Y, Hoshino T, Onuma H, An S, Nishio H, Saita Y, Sekiya I, Koga H. Intra-articular Injection of Pure Platelet-Rich Plasma Is the Most Effective Treatment for Joint Pain by Modulating Synovial Inflammation and Calcitonin Gene-Related Peptide Expression in a Rat Arthritis Model. Am J Sports Med. 2020 Jul;48(8):2004-2012. 43. Huang H, Nagao M, Nishio H, Kaneko H, Saita Y, Takazawa Y, Ikeda H, Kaneko K, Ishijima M. Remnant preservation provides good clinical outcomes after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2021 Jan 2. 44. Wakayama T, Saita Y, Kobayashi Y, Nishio H, Uchino S, Fukusato S, Ikeda H, Kaneko K. Quality comparison between two different types of platelet-rich plasma for knee osteoarthritis. Regen Med Res. 2020;8:3. 45. Kobayashi Y, Saita Y, Takaku T, Yokomizo T, Nishio H, Ikeda H, Takazawa Y, Nagao M, Kaneko K, Komatsu N. Platelet-rich plasma (PRP) accelerates murine patellar tendon healing through enhancement of angiogenesis and collagen synthesis. J Exp Orthop. 2020 Jul 8;7(1):49. 46. Saita Y. Risk/caution of vitamin D insufficiency for quarantined athletes returning to play after COVID-19. BMJ Open Sport Exerc Med. 2020 Oct 19;6(1):e000882. doi: 10.1136/bmjsem-2020-000882. 47. Baba T, Uchino M, Ochi H, Ikuta T, Saita Y, Hagino H, Nonomiya H, Jingushi S, Nakajima T, Ueda Y, Kazuo K. Atypical periprosthetic femoral fractures after arthroplasty for fracture are at high risk of complications. Sci Rep. 2021 11(1):14378. 48. Uchino S, Saita Y, Wada A, Kobayashi Y, Wakayama T, Nishio H, Fukusato S, Momoi Y, Nakajima R, Ikeda H, Ishijima M. The immature platelet fraction affects the efficacy of platelet rich plasma therapy for knee osteoarthritis. Regen Ther. 2021 18:176-181. 49. Romdhani M, Rae DE, Nédélec M, Ammar A, Chtourou H, Al Horani R, Ben Saad H, Bragazzi N, Dönmez G, Driss T, Fullagar HHK, Farooq A, Garbarino S, Hammouda O, Hassanmirzaei B, Khalladi K, Khemila S, Mataruna-Dos-Santos LJ, Moussa-Chamari I, Mujika I, Muñoz Helú H, Norouzi Fashkhami A, Paineiras-Domingos LL, Rahbari Khaneghah M, Saita Y, Trabelsi K, Vitale JA, Washif JA, Weber J, Souissi N, Taylor L, Chamari K. COVID-19 Lockdowns: A Worldwide Survey of Circadian Rhythms and Sleep Quality in 3911 Athletes from 49 Countries, with Data-Driven Recommendations. Sports Med. 2021 8:1–16. 50. Saita Y, Kobayashi Y, Nishio H, Wakayama T, Fukusato S, Uchino S, Momoi Y, Ikeda H, Kaneko K. Predictors of Effectiveness of Platelet-Rich Plasma Therapy for Knee Osteoarthritis: A Retrospective Cohort Study. J Clin Med. 2021 10(19):4514. 51. Okumura Y, Inomata T, Fujimoto K, Fujio K, Zhu J, Yanagawa A, Shokirova H, Saita Y, Kobayashi Y, Nagao M, Nishio H, Sung J, Midorikawa-Inomata A, Eguchi A, Nagino K, Akasaki Y, Hirosawa K, Huang T, Kuwahara M, Murakami A. Biological effects of stored platelet-rich plasma eye-drops in corneal wound healing. Br J Ophthalmol. 2022 26:bjo-2022-322068. 52. Romdhani M, Fullagar HHK, Vitale JA, Nédélec M, Rae DE, Ammar A, Chtourou H, Al Horani RA, Ben Saad H, Bragazzi NL, Dönmez G, Dergaa I, Driss T, Farooq A, Hammouda O, Harroum N, Hassanmirzaei B, Khalladi K, Khemila S, Mataruna-Dos-Santos LJ, Moussa-Chamari I, Mujika I, Muñoz Helú H, Norouzi Fashkhami A, Paineiras-Domingos LL, Khaneghah MR, Saita Y, Souissi N, Trabelsi K, Washif JA, Weber J, Zmijewski P, Taylor L, Garbarino S, Chamari K. Lockdown Duration and Training Intensity Affect Sleep Behavior in an International Sample of 1,454 Elite Athletes. Front Physiol. 2022 13:904778. 53. Wakayama T, Saita Y, Nagao M, Uchino S, Yoshihara SI, Tsuji K, Koga H, Kobayashi Y, Nishio H, Momoi Y, Ikeda H, Kaneko K, Ishijima M. Intra-Articular Injections of the Adipose-Derived Mesenchymal Stem Cells Suppress Progression of a Mouse Traumatic Knee Osteoarthritis Model. Cartilage. 2022 13(4):148-156. 54. Momoi Y, Saita Y, Nagao M, Kobayashi Y, Nakajima R, Uchino S, Wakayama T, Nishio H, Fukusato S, Wakana S, Tomura J, Kobayashi K, Yoshida K, Kaneko H, Kubota M, Ishijima M. Study protocol for a randomised placebo controlled trial of platelet-rich plasma injection to prevent post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction. BMJ Open. 2022 12(11):e061484.

研究テーマ

細胞治療　膝関節外科　骨代謝学　スポーツ医学　スポーツ外傷

研究業績（論文）

1. Ishikawa S, Arase N, Suenaga T, Saita Y, Noda M, Kuriyama T, Arase H, Saito T. Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). Int Immunol. 16:1019-25. 2004
2. Saita Y, Takagi T, Kitahara K, Usui M, Miyazono K, Ezura Y, Nakashima K, Kurosawa H, Ishii S, Noda M. Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia. J Biol Chem. 282:12907-15. 2007,
3. Kato N, Hasegawa U, Morimoto N, Saita Y, Nakashima K, Ezura Y, Kurosawa H, Akiyoshi K, Noda M. Nanogel-based delivery system enhances PGE2 effects on bone formation. J Cell Biochem.101:1063-70. 2007,
4. Saita Y, Nakamura T, Mizoguchi F, Nakashima K, Hemmi H, Hayata T, Ezura Y, Kurosawa H, Kato S, Noda M. Combinatory effects of androgen receptor deficiency and hind limb unloading on bone. Horm Metab Res. 41:822-8. 2009,
5. Hayashi C, Hasegawa U, Saita Y, Hemmi H, Hayata T, Nakashima K, Ezura Y, Amagasa T, Akiyoshi K, Noda M. Osteoblastic bone formation is induced by using nanogel-crosslinking hydrogel as novel scaffold for bone growth factor. J Cell Physiol.220:1-7.2009,
6. Liu L, Ishijima M, Futami I, Kaneko H, Kubota M, Kawasaki T, Matsumoto T, Kurihara H, Ning L, Xu Z, Ikeda H, Takazawa Y, Saita Y, Kimura Y, Xu S, Kaneko K, Kurosawa H. Correlation between synovitis detected on enhanced-magnetic resonance imaging and a histological analysis with a patient-oriented outcome measure for Japanese patients with end-stage knee osteoarthritis receiving joint replacement surgery. Clin Rheumatol. 29:1185-90. 2010,
7. Kubota M, Ishijima M, Kurosawa H, Liu L, Ikeda H, Osawa A, Takazawa Y, Kawasaki T, Saita Y, Kimura Y, Kaneko K. A longitudinal study of the relationship between the status of bone marrow abnormalities and progression of knee osteoarthritis. J Orthop Sci. 15:641-6. 2010,
8. Nagao M, Saita Y, Hanyu R, Hemmi H, Notomi T, Hayata T, Nakamoto T, Nakashima K, Kaneko K, Kurosawa H, Ishii S, Ezura Y, Noda M. Schnurri-2 deficiency counteracts against bone loss induced by ovariectomy. J Cell Physiol. 226:573-8. 2011,
9. Hanyu R, Hayata T, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Knonenbery H, Kaneko K, Kurosawa H, Ezura Y, Noda M. Per-1 is a specific clock gene regulated by parathyroid hormone (PTH) signaling in osteoblasts and is functional for the transcriptional events induced by PTH. J Cell Biochem. 112:433-8. 2011,
10. Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, Karsenty G, Denhardt DT, Vilardaga JP, Noda M. Sympathetic control of bone mass regulated by osteopontin. Proc Natl Acad Sci U S A. 108:17767-72. 2011,
11. Nojiri H, Saita Y, Morikawa D, Kobayashi K, Tsuda C, Miyazaki T, Saito M, Marumo K, Yonezawa I, Kaneko K, Shirasawa T, Shimizu T. Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking. J Bone Miner Res. 26:2682-94. 2011,
12. Hanyu R, Wehbi VL, Hayata T, Moriya S, Feinstein TN, Ezura Y, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Takeda S, Kaneko K, Kurosawa H, Karsenty G, Kronenberg HM, Vilardaga JP, Noda M. Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proc Natl Acad Sci U S A. 109:7433-8 2012,
13. Nagao M, Saita Y, Kameda S, Seto H, Sadatsuki R, Takazawa Y, Yoshimura M, Aoba Y, Ikeda H, Kaneko K, Nozawa M, Kim SG. Headless compression screw fixation of jones fractures: an outcomes study in Japanese athletes. Am J Sports Med. 40:2578-82. 2012,
14. Kaneko H, Ishijima M, Doi T, Futami I, Liu L, Sadatsuki R, Yusup A, Hada S, Kubota M, Kawasaki T, Saita Y, Takazawa Y, Ikeda H, Kurosawa H, Kaneko K. Reference intervals of serum hyaluronic acid corresponding to the radiographic severity of knee osteoarthritis in women. BMC Musculoskelet Disord. 18;14:34. 2013,
15. Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T. Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading. J Bone Miner Res. 28:2368-80. 2013,
16. Liu L, Ishijima M, Kaneko H, Futami I, Sadatsuki R, Hada S, Yusup A, Shimura Y, Kubota M, Saita Y, Takazawa Y, Ikeda H, Kurosawa H, Kaneko K. Disability for daily living is a predictor for joint replacement in patients with end-stage knee osteoarthritis. J Bone Miner Metab. 32:192-9. 2014,
17. Takazawa Y, Ikeda H, Ishijima M, Kubota M, Saita Y, Kaneko H, Kobayashi Y, Sadatsuki R, Hada S, Kaneko K. Reconstruction of a ruptured patellar tendon using ipsilateral semitendinosus and gracilis tendons with preserved distal insertions: two case reports. BMC Res Notes. 6:361. 2013,
18. Saita Y, Ishijima M, Mogami A, Kubota M, Baba T, Kaketa T, Nagao M, Sakamoto Y, Sakai K, Kato R, Nagura N, Miyagawa K, Wada T, Liu L, Obayashi O, Shitoto K, Nozawa M, Kajihara H, Gen H, Kaneko K. The fracture sites of atypical femoral fractures are associated with the weight-bearing lower limb alignment. Bone. 66:105-10. 2014,
19. Hada S, Kaneko H, Sadatsuki R, Liu L, Futami I, Kinoshita M, Yusup A, Saita Y, Takazawa Y, Ikeda H, Kaneko K, Ishijima M. The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis: a cross-sectional study. Osteoarthritis Cartilage. 22:1583-9. 2014,
20. Saita Y, Ishijima M, Mogami A, Kubota M, Baba T, Kaketa T, Nagao M, Sakamoto Y, Sakai K, Homma Y, Kato R, Nagura N, Miyagawa K, Wada T, Liu L, Matsuoka J, Obayashi O, Shitoto K, Nozawa M, Kajihara H, Gen H, Kaneko K. The incidence of and risk factors for developing atypical femoral fractures in Japan. J Bone Miner Metab. 33:311-8. 2015,
21. Nagao M, Doi T, Saita Y, Kobayashi Y, Kubota M, Kaneko H, Takazawa Y, Ishijima M, Kurosawa H, Kaneko K, Nozawa M, Ikeda H, Kim SG. A novel patient-reported outcome measure for anterior cruciate ligament injury: evaluating the reliability, validity, and responsiveness of Japanese anterior cruciate ligament questionnaire 25. Knee Surg Sports Traumatol Arthrosc. 2015 24(9):2973-2982,
22. Yusup A, Kaneko H, Liu L, Ning L, Sadatsuki R, Hada S, Kamagata K, Kinoshita M, Futami I, Shimura Y, Tsuchiya M, Saita Y, Takazawa Y, Ikeda H, Aoki S, Kaneko K, Ishijima M. Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee osteoarthritis: a cross-sectional study. Osteoarthritis Cartilage. 23(11):1858-1864. 2015,
23. Takazawa Y, Ikeda H, Saita Y, Ishijima M, Nagayama M, Kaneko H, Kobayashi Y, Hada S, Sadatsuki R, Kaneko K. Case series: Revision anterior cruciate ligament reconstructions using patellar tendon autografts. Knee. pii: S0968-0160(15)00139-8. 2015,
24. Kobayashi K, Nojiri H, Saita Y, Morikawa D, Ozawa Y, Watanabe K, Koike M, Asou Y, Shirasawa T, Yokote K, Kaneko K, Shimizu T. Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis. Sci Rep.5:9148. 2015,
25. Wakayama T, Saita Y, Baba T, Nojiri H, Kaneko K Pathological Relationship of Osteomalacia at the Site of Atypical Periprosthetic Femoral Shaft Fracture after Typical Femoral Neck Fracture Occurred in the Patient with Rheumatoid Arthritis: A Case Report J Rheum Dis Treat 2015,
26. Koike M, Nojiri H, Ozawa Y, Watanabe K, Muramatsu Y, Kaneko H, Morikawa D, Kobayashi K, Saita Y, Sasho T, Shirasawa T, Yokote K, Kaneko K, Shimizu T. Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration. Sci Rep.5:11722 2015,
27. Takazawa Y, Nagayama M, Ikeda H, Kawasaki T, Ishijima M, Saita Y, Kaneko H, Kobayashi Y, Hada S, Kaneko K. Anterior cruciate ligament injuries in elite and high school rugby players: a 11-year review. Phys Sportsmed.44:53-8. 2016,
28. Saita Y, Ishijima M, Kaneko K. Atypical femoral fractures and bisphosphonate use: current evidence and clinical implications. Ther Adv Chronic Dis. 6:185-93. Review. 2015,
29. Saita Y, Ikeda H, Kaneko K. Differences Between Sports Medicine in Europe and Japan. Juntendo Medical Journal 64 Page11-16 2018
30. Shimasaki Y, Nagao M, Miyamori T, Aoba Y, Fukushi N, Saita Y, Ikeda H, Kim SG, Nozawa M, Kaneko K, Yoshimura M. Evaluating the Risk of a Fifth Metatarsal Stress Fracture by Measuring the Serum 25-Hydroxyvitamin D Levels. Foot Ankle Int. 37:307-11. 2016,
31. Kubota M, Ikeda H, Takazawa Y, Ishijima M, Saita Y, Kaneko H, Kim SG, Kurosawa H, Kaneko K Preoperative assessments completed for anterior cruciate ligament reconstructions with remnant preservation. J Orthop. 14:S75-8. 2015,
32. Kobayashi Y, Saita Y, Nishio H, Ikeda H, Takazawa Y, Nagao M, Takaku T, Komatsu N, Kaneko K. Leukocyte concentration and composition in platelet-rich plasma (PRP) influences the growth factor and protease concentrations. J Orthop Sci. 21:683-9. 2016,
33. Takazawa Y, Ikeda H, Saita Y, Kawasaki T, Ishijima M, Nagayama M, Kaneko H, Kaneko K. Return to Play of Rugby Players After Anterior Cruciate Ligament Reconstruction Using Hamstring Autograft: Return to Sports and Graft Failure According to Age. Arthroscopy. 33:181-189. 2017,
34. Yoshida K, Itoigawa Y, Maruyama Y, Saita Y, Takazawa Y, Ikeda H, Kaneko K, Sakai T, Okuwaki T. Application of shear wave elastography for the gastrocnemius medial head to tennis leg. Clin Anat. 30:114-119. 2017,
35. Saita Y, Nagao M, Kawasaki T, Kobayashi Y, Kobayashi K, Nakajima H, Takazawa Y, Kaneko K, Ikeda H. Range limitation in hip internal rotation and fifth metatarsal stress fractures (Jones fracture) in professional football players. Knee Surg Sports Traumatol Arthrosc. 2018 26(7):1943-1949.
36. Mid and long term outcomes after fixation of osteochondritis dissecans Kubota M, Ishijima M, Ikeda H, Takazawa Y, Saita Y, Kaneko H, Kurosawa H, Kaneko K J Orthop. 2018 15: 536-539.
37. Saita Y, Schoenhuber H, Thiébat G, Ravasio G, Pozzoni R, Panzeri A, Galli M, Nagao M, Takazawa Y, Ikeda H, Kaneko K. Knee hyperextension and a small lateral condyle are associated with greater quantified antero-lateral rotatory instability in the patients with a complete anterior cruciate ligament (ACL) rupture. Knee Surg Sports Traumatol Arthrosc. 27(3):868-874. 2019
38. Miyamori T, Nagao M, Sawa R, Tumilty S, Yoshimura M, Saita Y, Ikeda H, Kaneko K.Playing football on artificial turf as a risk factor for fifth metatarsal stress fracture: a retrospective cohort study. BMJ Open. 9:e022864. 2019
39. Nishio H, Saita Y, Kobayashi Y, Takaku T, Fukusato S, Uchino S, Wakayama T, Ikeda H, Kaneko K. Platelet-rich plasma promotes recruitment of macrophages in the process of tendon healing. Regen Ther. 2020 14:262-270.
40. Huang H, Nagao M, Arita H, Nishio H, Kaneko H, Saita Y, Ishijima M, Takazawa Y, Ikeda H, Kaneko K. Validation and defining the minimal clinically important difference of the Japanese version of the IKDC Subjective Knee Form. J Orthop Sci. 2020 Online ahead of print.
41. Huang H, Nagao M, Arita H, Shiozawa J, Nishio H, Kobayashi Y, Kaneko H, Nagayama M, Saita Y, Ishijima M, Takazawa Y, Ikeda H, Kaneko K. Reproducibility, responsiveness and validation of the Tampa Scale for Kinesiophobia in patients with ACL injuries. Health Qual Life Outcomes. 2019 17(1):150.
42. Araya N, Miyatake K, Tsuji K, Katagiri H, Nakagawa Y, Hoshino T, Onuma H, An S, Nishio H, Saita Y, Sekiya I, Koga H. Intra-articular Injection of Pure Platelet-Rich Plasma Is the Most Effective Treatment for Joint Pain by Modulating Synovial Inflammation and Calcitonin Gene-Related Peptide Expression in a Rat Arthritis Model. Am J Sports Med. 2020 Jul;48(8):2004-2012.
43. Huang H, Nagao M, Nishio H, Kaneko H, Saita Y, Takazawa Y, Ikeda H, Kaneko K, Ishijima M. Remnant preservation provides good clinical outcomes after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2021 Jan 2.
44. Wakayama T, Saita Y, Kobayashi Y, Nishio H, Uchino S, Fukusato S, Ikeda H, Kaneko K. Quality comparison between two different types of platelet-rich plasma for knee osteoarthritis. Regen Med Res. 2020;8:3.
45. Kobayashi Y, Saita Y, Takaku T, Yokomizo T, Nishio H, Ikeda H, Takazawa Y, Nagao M, Kaneko K, Komatsu N. Platelet-rich plasma (PRP) accelerates murine patellar tendon healing through enhancement of angiogenesis and collagen synthesis. J Exp Orthop. 2020 Jul 8;7(1):49.
46. Saita Y. Risk/caution of vitamin D insufficiency for quarantined athletes returning to play after COVID-19. BMJ Open Sport Exerc Med. 2020 Oct 19;6(1):e000882. doi: 10.1136/bmjsem-2020-000882.
47. Baba T, Uchino M, Ochi H, Ikuta T, Saita Y, Hagino H, Nonomiya H, Jingushi S, Nakajima T, Ueda Y, Kazuo K. Atypical periprosthetic femoral fractures after arthroplasty for fracture are at high risk of complications. Sci Rep. 2021 11(1):14378.
48. Uchino S, Saita Y, Wada A, Kobayashi Y, Wakayama T, Nishio H, Fukusato S, Momoi Y, Nakajima R, Ikeda H, Ishijima M. The immature platelet fraction affects the efficacy of platelet rich plasma therapy for knee osteoarthritis. Regen Ther. 2021 18:176-181.
49. Romdhani M, Rae DE, Nédélec M, Ammar A, Chtourou H, Al Horani R, Ben Saad H, Bragazzi N, Dönmez G, Driss T, Fullagar HHK, Farooq A, Garbarino S, Hammouda O, Hassanmirzaei B, Khalladi K, Khemila S, Mataruna-Dos-Santos LJ, Moussa-Chamari I, Mujika I, Muñoz Helú H, Norouzi Fashkhami A, Paineiras-Domingos LL, Rahbari Khaneghah M, Saita Y, Trabelsi K, Vitale JA, Washif JA, Weber J, Souissi N, Taylor L, Chamari K. COVID-19 Lockdowns: A Worldwide Survey of Circadian Rhythms and Sleep Quality in 3911 Athletes from 49 Countries, with Data-Driven Recommendations. Sports Med. 2021 8:1–16.
50. Saita Y, Kobayashi Y, Nishio H, Wakayama T, Fukusato S, Uchino S, Momoi Y, Ikeda H, Kaneko K. Predictors of Effectiveness of Platelet-Rich Plasma Therapy for Knee Osteoarthritis: A Retrospective Cohort Study. J Clin Med. 2021 10(19):4514.
51. Okumura Y, Inomata T, Fujimoto K, Fujio K, Zhu J, Yanagawa A, Shokirova H, Saita Y, Kobayashi Y, Nagao M, Nishio H, Sung J, Midorikawa-Inomata A, Eguchi A, Nagino K, Akasaki Y, Hirosawa K, Huang T, Kuwahara M, Murakami A. Biological effects of stored platelet-rich plasma eye-drops in corneal wound healing. Br J Ophthalmol. 2022 26:bjo-2022-322068.
52. Romdhani M, Fullagar HHK, Vitale JA, Nédélec M, Rae DE, Ammar A, Chtourou H, Al Horani RA, Ben Saad H, Bragazzi NL, Dönmez G, Dergaa I, Driss T, Farooq A, Hammouda O, Harroum N, Hassanmirzaei B, Khalladi K, Khemila S, Mataruna-Dos-Santos LJ, Moussa-Chamari I, Mujika I, Muñoz Helú H, Norouzi Fashkhami A, Paineiras-Domingos LL, Khaneghah MR, Saita Y, Souissi N, Trabelsi K, Washif JA, Weber J, Zmijewski P, Taylor L, Garbarino S, Chamari K. Lockdown Duration and Training Intensity Affect Sleep Behavior in an International Sample of 1,454 Elite Athletes. Front Physiol. 2022 13:904778.
53. Wakayama T, Saita Y, Nagao M, Uchino S, Yoshihara SI, Tsuji K, Koga H, Kobayashi Y, Nishio H, Momoi Y, Ikeda H, Kaneko K, Ishijima M. Intra-Articular Injections of the Adipose-Derived Mesenchymal Stem Cells Suppress Progression of a Mouse Traumatic Knee Osteoarthritis Model. Cartilage. 2022 13(4):148-156.
54. Momoi Y, Saita Y, Nagao M, Kobayashi Y, Nakajima R, Uchino S, Wakayama T, Nishio H, Fukusato S, Wakana S, Tomura J, Kobayashi K, Yoshida K, Kaneko H, Kubota M, Ishijima M. Study protocol for a randomised placebo controlled trial of platelet-rich plasma injection to prevent post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction. BMJ Open. 2022 12(11):e061484.

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