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研究業績詳細

土井崇（ドイタカシ）

研究テーマ	先天性横隔膜ヘルニアに伴う肺低形成、及び臍帯ヘルニアの分子学的機序の究明
研究業績（論文）	英文原著 1) Doi T, Kobayashi H, Yamataka A, et al: Complete innervations profile of whole bowel resected dat pull-through for Hrschsprung’s disease. Unexpected findings. Pediatr Surg Int 21:889-898, 2005 2) Miyano G, Yamataka A, Doi T, Miyano T, et al: Carbon dioxide pneumoperitoneum prevents intraperitoneal adhesions after laparotomy in rats. J Pediatr Surg 41(5):1025-8, 2006 3) Doi T, Ichikawa S, Miyano G, Yamataka A, et al: A new tehniaue for preventing wrap disruption/migration after laparoscopic Nissen fundoplication: an experiental study. J Laparoendosc Adv Surg Tech A 8:179-182, 2008 4) Doi T, Puri P, Bannigan J and Thompson J: Downregulation of rock-I and rock-II gene expression in the cadmium-induced ventral body wall defect chick model. Pediatr Surg Int 24:1297-1301, 2008 5) Doi T, Sugimoto K and Puri P: Prenatal retinoic acid upregulates pulmonary gene expression of COUP TFII, FOG 2 and GATA 4 in pulmonary hypoplasia. J Pediatr Surg 44(10):1933-1937, 2009 6) Doi T, Sugimoto K and Puri P: Upreglation of COUP-TFII gene expression in the nitrofen induced hypoplastic lung. J Pediatr Surg 44(2):321-324, 2009. 7) Doi T, Hajduk P, Puri P: Upregulation of SLIT-2 and SLIT-3 gene expressions in the nitrofen induced hypoplastic lung..J Pediatr Surg 44(11):2092-2095, 2009 8) Doi T and Puri P: Upregulation of WNT　5A gene expression in thenitrofen-induced hypoplastic lung. J Pediatr Surg 44(12):2302-2306, 2009 9) Doi T, Ruttenstock E, Dingemann J and Puri P：Spatio-temporal alteration in PI3K-AKT signalling in the nitrofen induced hypoplastic lung. J Pediatr Surg 45(2):366-371, 2010 10) Doi T, Puri P, Bannigan J and Thompson J: Disruption of non-canonical WNT/CA2+ pathway in the cadmium-induced inogakicele in the chick model. DISRUPTION OF NON-CANONICAL WNT/CA2+ PATHWAY IN THE CADMIUM-INDUCED OMPHALOCELE IN THE CHICK MODEL. J Pediatr Surg 45(8):1645-9, 2010 11) Doi T, Ruttenstock E, Dingemann J Puri P: Disturbance of parathyroid hormone-related protein signalling in the nitrofen-induced hypoplastic lung Pediatr Surg IntJan;26(1):45-50, 2010 12) Doi T, Puri P, Bannigan J and Thompson J: Disruption of calreticulin-mediated adhesion signalling in the cadmium-induced omphalocele chick model. Pediatr Surg Int 26(1):91-95, 2010 13) Doi T, Puri P, Bannigan J and Thompson J: The role of transforming growth factor beta 2 and 3 in the formation of ventral body wall in the cadmium induced omphalocele chick model. J Pediatr Surg 45(5):898-902, 2010 14) Doi T, Puri P, Bannigan J and Thompson J: Downregulation msx1/msx2 gene expression in the cadmium-induced omphalocele chick model. J Pediatr Surg. 45(6):1187-1191, 2010 15) Doi T, Sugimoto K, Ruttenstock E, Dingemann J and Puri P: Prenatal retinoic acid upregulates pulmonary gene expression of pi3k and akt in nitrofen-induced pulmonary hypoplasia. Pediatr Surg Int 27(1)47-52, 2011 16) Doi T, Puri P, Bannigan J and Thompson J: HOXB2, HOXB4 and ALX4 genes are downregulated in the cadmium-induced omphalocele in the chick model Pediatr Surg Int 26(10)1017-1023, 2010. 17) Doi T, Shintaku M, Dingemann J, Ruttenstock E and Puri P: Downregulation of midkine gene expression and its response to retinoic acid treatment in thenitrofen-induced hypoplastic lung. Pediatr Surg Int 27(2)199-204, 2011 18) Doi T, Puri P, Bannigan J and Thompson J: Disruption of GLI3-ZIC3 interaction in the cadmium-induced omphalocele chick model. Pediatr Surg Int 27(2)205-209, 2011 19) Doi T, Puri P, Bannigan J and Thompson J: Pre-treatment with n-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model. Pediatr Surg Int 27(2)131-136, 2011 20) Doi T, Lukošiūtė A, Ruttenstock E, Dingemann J and Puri P: Expression of iroquois genes is upregulated during early lung development in the nitrofen induced pulmonary hypoplasia. J Pediatr Surg 46(1)62-66, 2011 21) Doi T, Puri P, Bannigan J and Thompson J: BMPR1A-mediated BMP1 signalling is disrupted in the cadmium-induced omphalocele in the chick model　Pediatr Surg Int 27(6)617-621, 2011 22) Doi T, Prem Puri, John Bannigan and Jennifer Thompson: Altered PITX2 and lef1 gene expression in the cadmium-induced omphalocele in the chick model. Pediatr Surg Int　27(5)495-499, 2011 23) O'Donnell AM, Doi T, Höllwarth M, Kalicinski P, Czauderna P, Puri P: Deficient of α-smooth muscle actin as a cause of functional intestinal obstruction in childhood. Pediatr Surg Int 24(11):1191-5, 2008 24) Ruttenstock E, Doi T, Dingemann J, Puri P: Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia. Pediatr Surg Int 26(1):59-63, 2010 25) Dingemann J, Doi T, Ruttenstock E, Puri P: Upregulation of endothelin receptors a and b in the nitrofen induced hypoplastic lung occurs early in gestation. Pediatr Surg Int 26(1):65-9, 2010 26) Thompson J, Doi T, Power E, Balasubramanian I, Puri P, Bannigan J: Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo. Toxicol Appl Pharmacol 243(3):390-398, 2010 27) Ruttenstock E, Doi T, Dingemann J, Puri P: Insulin-like growth factor receptor type 1 and type 2 are downregulated in the nitrofen-induced hypoplastic lung. J Pediatr Surg 45(6):1349-53, 2010 28) Ruttenstock E, Doi T, Dingemann J, Puri P: Insulin receptor is downregulated in the nitrofen-induced hypoplastic lung.J Pediatr Surg 45(5):948-52, 2010 29) Takayasu H, Murphy P, Sato H, Doi T, Puri P: Embryonic WNT gene expression in the nitrofen-induced hypoplastic lung using 3-dimensional imaging. J Pediatr Surg. 45(11):2129-2135, 2010. 30) Dingemann J, Doi T, Ruttenstock E, Puri P: Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia. J Pediatr Surg 45(10):1989-94, 2010 31) Ruttenstock EM, Doi T, Dingemann J, Puri P: IGFBP-4 gene overexpression in the nitrofen-induced hypoplastic lung Eur J Pediatr Surg 21(1)42-45, 2011 32) Dingemann J, Doi T, Ruttenstock EM, Puri P: Downregulation of FGFRL1 contributes to the development of the diaphragmatic defect in the nitrofen model of congenital diaphragmatic hernia. Eur J Pediatr Surg 21(1)46-9, 2011 33) Lukošiūtė A, Doi T, Dingemann J, Ruttenstock EM, Puri P: Down-regulation of lung kruppel-like factor in the nitrofen-induced hypoplastic lung. Eur J Pediatr Surg 21(1)38-41, 2011 34) Ruttenstock EM, Doi T, Dingemann J, Puri P: Prenatal retinoic acid treatment upregulates late gestation lung protein 1 in the nitrofen-induced hypoplastic lung in late gestation. Pediatr Surg Int 27(2)125-129, 2011 35) Dingemann J, Doi T, Ruttenstock E, Puri P: Expression of the Wilm's tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia. Pediatr Surg Int 27(2)159-163, 2011 36) Ruttenstock EM, Doi T, Dingemann J, Puri P: Prenatal administration of retinoic acid upregulates connective tissue growth factor (CTGF) in the nitrofen CDH model. Pediatr Surg Int 27(6)573-577, 2011 37) Dingemann J, Doi T, Ruttenstock E, Puri P: The role of primary myogenic regulatory factors in the developing diaphragmatic muscle in the nitrofen induced diaphragmatic hernia. Pediatr Surg Int 27(6)579-582, 2011 Presentations: 1) Doi T, Yanai T, Yamataka A, Miyano T, et al. : Lung injury and diaphragmatic hernia caused by multiple exostoses (International session/ Japanese Society of Pediatric Surgery 2003) 2) Doi T, Kobayasshi H, Yamataka A, et al. : Complete innervation profile of whole bowel resected at pull-through for Hirschsprung’s disease. unexpected findings (International session/ Japanese Society of Pediatric Surgery 2004) 3) Doi T, Ichikawa S, Miyano G, Yamataka A, et al.: A new technique for preventing wrap disruption/migration after laparoscopic nissen fundoplication: an experimental study.(Poster presentation/ Annual Congress for Endosurgery in Children 2007) 4) Doi T, Sugimoto K, Puri P: Prenatal retinoic acid upregulates pulmonary gene expression of COUP-TFII, FOG2 AND GATA4 in pulmonary hypoplasia (Oral Presentation in Young Investigator Award Session/ European Pediatric Surgeons’ Association 2008) 5) O’Donnell AM, Doi T, Puri P, et al.: Deficient of α-smooth muscle actin as a cause of functional intestinal obstruction in childhood (Oral Presentation/ Colorectal Club 2008) 6) Doi T, Sugimoto K and Puri P: Upregulation of COUP-TFII gene expression in the nitrofen induced hypoplastic lung (Oral Presentation/ British Association of Pediatric Surgeons 2008) 7) Doi T, Bannigan J, Thompson J and Puri P: Downregulation of ROCK-I and ROCK-II gene expression in the cadmium-induced ventral wall defect chick model. (Oral Presentation in Novartis Prize Session/ International Symposium of Pediatric Surgical Research Meeting 2008) 8) Doi T and Puri P: Upregulation of SLIT-2 and SLIT-3 gene expression in the nitrofen induced hypoplastic lung (Poster with Oral Presentation/ American Academy of Pediatrics 2008) 9) Doi T and Puri P: Upregulation of WNT5A gene expression in the nitrofen-induced hypoplastic lung. 42nd Annual Meeting of Pacific Association of Pediatric Surgeons (Hong Kong, China) 10-14, May, 2009 [6min Oral Presentation] 10) Doi T, Thompson J, Bannigan J and Puri P: Downregulation of AP-2alpha gene expression in the cadmium-induced omphalocele chick model. Annual Meeting of Japanese Society of Pediatric Surgeons (Osaka, Japan) 1-3, June, 2009 [6min Oral Presentation] 11) Doi T, Ruttenstock E, Dingemann J and Puri P: Spatio-temporal alteration in PI3K-AKT signalling in the nitrofen induced hypoplastic lung. EUPSA&BAPS Joint Meeting (Graz, Austria) 17-20, June, 2009 [8min Oral Presentation in Peter Paul Rickham & Young Investigator Prize Session] 12) Doi T, Thompson J, Bannigan J and Puri P: Non-canonical WNT/calcium pathway is disrupted in the cadmium-induced omphalocele chick model. EUPSA&BAPS Joint Meeting (Graz, Austria) 17-20, June, 2009 [6min Oral Presentation] 13) Doi T, Puri P, Bannigan J and Thompson J: Alteration of canonical WNT pathway in the cadmium-induced omphalocoel in the chick model. Annual Meeting of European Teratology Society (Arles, France) 6-10 Sep, 2009 [10min Oral Presentation] 14) Doi T, Ruttenstock E, Dingemann J and Puri P: Disturbance of parathyroid hormone-related protein signalling in the nitrofen-induced hypoplastic lung. International Symposium on Paediatric Surgical Research (Genoa, Italy) 15-17, Sep, 2009 [8min Oral Presentation in Aesculap Prize Session] 15) Doi T, Thompson J, Bannigan J and Puri P: Disruption of calreticulin-mediated adhesion signalling in the cadmium-induced omphalocele chick model. International Symposium on Paediatric Surgical Research (Genoa, Italy) 15-17, Sep, 2009 [8min Oral Presentation in Aesculap Prize Session] 16) Doi T, Thompson J, Bannigan J and Puri P: The role of transforming growth factor-beta 2 and 3 in the formation of ventral body wall in the cadmium-induced omphalocele chick model. Canadian Association of Pediatric Surgery (Halifax, Canada) 1-3, Oct, 2009 [7min Oral Presentation] 17) Doi T, Thompson J, Bannigan J and Puri P: Downregulation MSX1/MSX2 gene expression in the cadmium-induced omphalocele chick model. Surgical Session of American Association of Pediatrics (Washington DC, USA) 15-20 Oct, 2009 [Poster with 2min Oral Presentation] 18) Doi T, Sugimoto K, Ruttenstock E, Dingemann J and Puri P: Prenatal retinoic acid upregulates pulmonary gene expression of PI3K and AKT in nitrofen-induced pulmonary hypoplasia. 22nd Congress of Asian Association of Pediatric Surgeons (Kuala Lumpur, Malaysia) 20-24, Feb, 2010 [10min Oral Presentation in Award Session] 19) Doi T, Thompson J, Bannigan J and Puri P: HOXB2, HOXB4 AND ALX4 genes are downregulated in the cadmium-induced omphalocele in the chick model. 22nd Congress of Asian Association of Pediatric Surgeons (Kuala Lumpur, Malaysia) 20-24, Feb, 2010 [10min Oral Presentation in Award Session] 20) Doi T, Lukošiūtė A, Ruttenstock E, Dingemann J and Puri P: Expression of iroquois genes is upregulated during early lung development in the nitrofen induced pulmonary hypoplasia. American Pediatric Surgical Association (Orlando, FL, USA) 16-19, May, 2010 [3min Oral/Poster Presentation] 21) Doi T, Thompson J, Bannigan J and Puri P: Epigenetic effect of cadmium on de novo dna hypomethylation in the cadmium-induced omphalocele in the chick model Annual Meeting of European Paediatric Surgeon’s Association (Bern, Switzerland) 2-5, June, 2010 [10min Oral Presentation in Young Investigator Award Session] 22) Doi T, Thompson J, Bannigan J and Puri P: failure of interaction of iqgap1 with rho-family gtpases in the cadmium-induced omphalocele in the chick model. Annual Congress of British Association of Paediatric Surgeons (Aberdeen, Scotland) 22-24 July, 2010 [10min Oral Presentation in Peter Paul Rickham Prize Session] 23) Doi T, Thompson J, Bannigan J and Puri P: Pre-treatment with n-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation in Aesculap Prize Session] 24) Doi T, Dingemann J, Ruttenstock E and Puri P: Expression of the wilm’s tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation in Aesculap Prize Session] 25) Doi T, Thompson J, Bannigan J and Puri P: Disruption of GLI3-ZIC3 interaction in the cadmium-induced omphalocele in the chick model. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation] 26) Doi T, Shintaku M, Ruttenstock E, Dingemann J and Puri P: Downregulation of midkine gene expression and its response to retinoic acid treatment in the nitrofen-induced hypoplastic lung. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation] 27) Doi T, Thompson J, Bannigan J and Puri P: BMPR1A-mediated BMP1 signalling is disrupted in the cadmium-induced omphalocele in the chick model.3rd World Congress of Pediatric Surgery (New Delhi, India) 21-24 Oct, 2010 [6min Oral Presentation] 28) Doi T, Thompson J, Bannigan J and Puri P: Altered PITX2 and LEF1 gene expression in the cadmium-induced omphalocele in the chick model.3rd World Congress of Pediatric Surgery (New Delhi, India) 21-24 Oct, 2010 [6min Oral Presentation]

研究テーマ

先天性横隔膜ヘルニアに伴う肺低形成、及び臍帯ヘルニアの分子学的機序の究明

研究業績（論文）

英文原著

1) Doi T, Kobayashi H, Yamataka A, et al:
Complete innervations profile of whole bowel resected dat pull-through for Hrschsprung’s disease. Unexpected findings. Pediatr Surg Int 21:889-898, 2005

2) Miyano G, Yamataka A, Doi T, Miyano T, et al: Carbon dioxide pneumoperitoneum prevents intraperitoneal adhesions after laparotomy in rats. J Pediatr Surg 41(5):1025-8, 2006

3) Doi T, Ichikawa S, Miyano G, Yamataka A, et al:
A new tehniaue for preventing wrap disruption/migration after laparoscopic Nissen fundoplication: an experiental study.
J Laparoendosc Adv Surg Tech A 8:179-182, 2008

4) Doi T, Puri P, Bannigan J and Thompson J:
Downregulation of rock-I and rock-II gene expression in the cadmium-induced ventral body wall defect chick model. Pediatr Surg Int 24:1297-1301, 2008

5) Doi T, Sugimoto K and Puri P: Prenatal retinoic acid upregulates pulmonary gene expression of COUP TFII, FOG 2 and GATA 4 in pulmonary hypoplasia. J Pediatr Surg 44(10):1933-1937, 2009

6) Doi T, Sugimoto K and Puri P: Upreglation of COUP-TFII gene expression in the nitrofen induced hypoplastic lung. J Pediatr Surg 44(2):321-324, 2009.

7) Doi T, Hajduk P, Puri P: Upregulation of SLIT-2 and SLIT-3 gene expressions in the nitrofen induced hypoplastic lung..J Pediatr Surg 44(11):2092-2095, 2009

8) Doi T and Puri P: Upregulation of WNT　5A gene expression in thenitrofen-induced hypoplastic lung. J Pediatr Surg 44(12):2302-2306, 2009

9) Doi T, Ruttenstock E, Dingemann J and Puri P：Spatio-temporal alteration in PI3K-AKT signalling in the nitrofen induced hypoplastic lung. J Pediatr Surg 45(2):366-371, 2010

10) Doi T, Puri P, Bannigan J and Thompson J: Disruption of non-canonical WNT/CA2+ pathway in the cadmium-induced inogakicele in the chick model.
DISRUPTION OF NON-CANONICAL WNT/CA2+ PATHWAY IN THE CADMIUM-INDUCED OMPHALOCELE IN THE CHICK MODEL. J Pediatr Surg 45(8):1645-9, 2010

11) Doi T, Ruttenstock E, Dingemann J Puri P: Disturbance of parathyroid hormone-related protein signalling in the nitrofen-induced hypoplastic lung Pediatr Surg IntJan;26(1):45-50, 2010

12) Doi T, Puri P, Bannigan J and Thompson J: Disruption of calreticulin-mediated adhesion signalling in the cadmium-induced omphalocele chick model. Pediatr Surg Int 26(1):91-95, 2010

13) Doi T, Puri P, Bannigan J and Thompson J: The role of transforming growth factor beta 2 and 3 in the formation of ventral body wall in the cadmium induced omphalocele chick model. J Pediatr Surg 45(5):898-902, 2010

14) Doi T, Puri P, Bannigan J and Thompson J: Downregulation msx1/msx2 gene expression in the cadmium-induced omphalocele chick model. J Pediatr Surg. 45(6):1187-1191, 2010

15) Doi T, Sugimoto K, Ruttenstock E, Dingemann J and Puri P: Prenatal retinoic acid upregulates pulmonary gene expression of pi3k and akt in nitrofen-induced pulmonary hypoplasia. Pediatr Surg Int 27(1)47-52, 2011

16) Doi T, Puri P, Bannigan J and Thompson J: HOXB2, HOXB4 and ALX4 genes are downregulated in the cadmium-induced omphalocele in the chick model
Pediatr Surg Int 26(10)1017-1023, 2010.

17) Doi T, Shintaku M, Dingemann J, Ruttenstock E and Puri P:
Downregulation of midkine gene expression and its response to retinoic acid treatment in thenitrofen-induced hypoplastic lung. Pediatr Surg Int 27(2)199-204, 2011

18) Doi T, Puri P, Bannigan J and Thompson J:
Disruption of GLI3-ZIC3 interaction in the cadmium-induced omphalocele chick model. Pediatr Surg Int 27(2)205-209, 2011

19) Doi T, Puri P, Bannigan J and Thompson J: Pre-treatment with n-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model. Pediatr Surg Int 27(2)131-136, 2011

20) Doi T, Lukošiūtė A, Ruttenstock E, Dingemann J and Puri P: Expression of iroquois genes is upregulated during early lung development in the nitrofen induced pulmonary hypoplasia. J Pediatr Surg 46(1)62-66, 2011

21) Doi T, Puri P, Bannigan J and Thompson J: BMPR1A-mediated BMP1 signalling is disrupted in the cadmium-induced omphalocele in the chick model　Pediatr Surg Int 27(6)617-621, 2011

22) Doi T, Prem Puri, John Bannigan and Jennifer Thompson: Altered PITX2 and lef1 gene expression in the cadmium-induced omphalocele in the chick model. Pediatr Surg Int　27(5)495-499, 2011

23) O'Donnell AM, Doi T, Höllwarth M, Kalicinski P, Czauderna P, Puri P: Deficient of α-smooth muscle actin as a cause of functional intestinal obstruction in childhood. Pediatr Surg Int 24(11):1191-5, 2008

24) Ruttenstock E, Doi T, Dingemann J, Puri P: Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia. Pediatr Surg Int 26(1):59-63, 2010

25) Dingemann J, Doi T, Ruttenstock E, Puri P: Upregulation of endothelin receptors a and b in the nitrofen induced hypoplastic lung occurs early in gestation. Pediatr Surg Int 26(1):65-9, 2010

26) Thompson J, Doi T, Power E, Balasubramanian I, Puri P, Bannigan J: Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo. Toxicol Appl Pharmacol 243(3):390-398, 2010

27) Ruttenstock E, Doi T, Dingemann J, Puri P: Insulin-like growth factor receptor type 1 and type 2 are downregulated in the nitrofen-induced hypoplastic lung. J Pediatr Surg 45(6):1349-53, 2010

28) Ruttenstock E, Doi T, Dingemann J, Puri P: Insulin receptor is downregulated in the nitrofen-induced hypoplastic lung.J Pediatr Surg 45(5):948-52, 2010

29) Takayasu H, Murphy P, Sato H, Doi T, Puri P: Embryonic WNT gene expression in the nitrofen-induced hypoplastic lung using 3-dimensional imaging. J Pediatr Surg. 45(11):2129-2135, 2010.

30) Dingemann J, Doi T, Ruttenstock E, Puri P: Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia. J Pediatr Surg 45(10):1989-94, 2010

31) Ruttenstock EM, Doi T, Dingemann J, Puri P: IGFBP-4 gene overexpression in the nitrofen-induced hypoplastic lung Eur J Pediatr Surg 21(1)42-45, 2011

32) Dingemann J, Doi T, Ruttenstock EM, Puri P: Downregulation of FGFRL1 contributes to the development of the diaphragmatic defect in the nitrofen model of congenital diaphragmatic hernia. Eur J Pediatr Surg 21(1)46-9, 2011

33) Lukošiūtė A, Doi T, Dingemann J, Ruttenstock EM, Puri P: Down-regulation of lung kruppel-like factor in the nitrofen-induced hypoplastic lung. Eur J Pediatr Surg 21(1)38-41, 2011

34) Ruttenstock EM, Doi T, Dingemann J, Puri P: Prenatal retinoic acid treatment upregulates late gestation lung protein 1 in the nitrofen-induced hypoplastic lung in late gestation. Pediatr Surg Int 27(2)125-129, 2011

35) Dingemann J, Doi T, Ruttenstock E, Puri P: Expression of the Wilm's tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia. Pediatr Surg Int 27(2)159-163, 2011

36) Ruttenstock EM, Doi T, Dingemann J, Puri P: Prenatal administration of retinoic acid upregulates connective tissue growth factor (CTGF) in the nitrofen CDH model.
Pediatr Surg Int 27(6)573-577, 2011

37) Dingemann J, Doi T, Ruttenstock E, Puri P: The role of primary myogenic regulatory factors in the developing diaphragmatic muscle in the nitrofen induced diaphragmatic hernia. Pediatr Surg Int 27(6)579-582, 2011

Presentations:

1) Doi T, Yanai T, Yamataka A, Miyano T, et al. : Lung injury and diaphragmatic hernia caused by multiple exostoses (International session/ Japanese Society of Pediatric Surgery 2003)

2) Doi T, Kobayasshi H, Yamataka A, et al. : Complete innervation profile of whole bowel resected at pull-through for Hirschsprung’s disease. unexpected findings
(International session/ Japanese Society of Pediatric Surgery 2004)

3) Doi T, Ichikawa S, Miyano G, Yamataka A, et al.: A new technique for preventing wrap disruption/migration after laparoscopic nissen fundoplication: an experimental
study.(Poster presentation/ Annual Congress for Endosurgery in Children 2007)

4) Doi T, Sugimoto K, Puri P:
Prenatal retinoic acid upregulates pulmonary gene expression of COUP-TFII, FOG2 AND GATA4 in pulmonary hypoplasia (Oral Presentation in Young Investigator Award Session/ European Pediatric Surgeons’ Association 2008)

5) O’Donnell AM, Doi T, Puri P, et al.:
Deficient of α-smooth muscle actin as a cause of functional intestinal obstruction in childhood (Oral Presentation/ Colorectal Club 2008)

6) Doi T, Sugimoto K and Puri P: Upregulation of COUP-TFII gene expression in the nitrofen induced hypoplastic lung (Oral Presentation/ British Association of Pediatric Surgeons 2008)

7) Doi T, Bannigan J, Thompson J and Puri P: Downregulation of ROCK-I and ROCK-II gene expression in the cadmium-induced ventral wall defect chick model.
(Oral Presentation in Novartis Prize Session/ International Symposium of Pediatric
Surgical Research Meeting 2008)

8) Doi T and Puri P:
Upregulation of SLIT-2 and SLIT-3 gene expression in the nitrofen induced hypoplastic lung (Poster with Oral Presentation/ American Academy of Pediatrics 2008)

9) Doi T and Puri P:
Upregulation of WNT5A gene expression in the nitrofen-induced hypoplastic lung.
42nd Annual Meeting of Pacific Association of Pediatric Surgeons (Hong Kong, China) 10-14, May, 2009 [6min Oral Presentation]

10) Doi T, Thompson J, Bannigan J and Puri P: Downregulation of AP-2alpha gene expression in the cadmium-induced omphalocele chick model. Annual Meeting of Japanese Society of Pediatric Surgeons (Osaka, Japan) 1-3, June, 2009 [6min Oral Presentation]

11) Doi T, Ruttenstock E, Dingemann J and Puri P: Spatio-temporal alteration in PI3K-AKT signalling in the nitrofen induced hypoplastic lung. EUPSA&BAPS Joint Meeting (Graz, Austria) 17-20, June, 2009 [8min Oral Presentation in Peter Paul Rickham & Young Investigator Prize Session]

12) Doi T, Thompson J, Bannigan J and Puri P: Non-canonical WNT/calcium pathway is disrupted in the cadmium-induced omphalocele chick model. EUPSA&BAPS Joint Meeting (Graz, Austria) 17-20, June, 2009 [6min Oral Presentation]

13) Doi T, Puri P, Bannigan J and Thompson J: Alteration of canonical WNT pathway in the cadmium-induced omphalocoel in the chick model. Annual Meeting of European Teratology Society (Arles, France) 6-10 Sep, 2009 [10min Oral Presentation]

14) Doi T, Ruttenstock E, Dingemann J and Puri P: Disturbance of parathyroid hormone-related protein signalling in the nitrofen-induced hypoplastic lung. International Symposium on Paediatric Surgical Research (Genoa, Italy) 15-17, Sep, 2009 [8min Oral Presentation in Aesculap Prize Session]

15) Doi T, Thompson J, Bannigan J and Puri P: Disruption of calreticulin-mediated adhesion signalling in the cadmium-induced omphalocele chick model. International Symposium on Paediatric Surgical Research (Genoa, Italy) 15-17, Sep, 2009 [8min Oral Presentation in Aesculap Prize Session]

16) Doi T, Thompson J, Bannigan J and Puri P: The role of transforming growth factor-beta 2 and 3 in the formation of ventral body wall in the cadmium-induced omphalocele chick model. Canadian Association of Pediatric Surgery (Halifax, Canada) 1-3, Oct, 2009 [7min Oral Presentation]

17) Doi T, Thompson J, Bannigan J and Puri P: Downregulation MSX1/MSX2 gene expression in the cadmium-induced omphalocele chick model. Surgical Session of American Association of Pediatrics (Washington DC, USA) 15-20 Oct, 2009 [Poster with 2min Oral Presentation]

18) Doi T, Sugimoto K, Ruttenstock E, Dingemann J and Puri P:
Prenatal retinoic acid upregulates pulmonary gene expression of PI3K and AKT in nitrofen-induced pulmonary hypoplasia. 22nd Congress of Asian Association of Pediatric Surgeons (Kuala Lumpur, Malaysia) 20-24, Feb, 2010 [10min Oral Presentation in Award Session]

19) Doi T, Thompson J, Bannigan J and Puri P:
HOXB2, HOXB4 AND ALX4 genes are downregulated in the cadmium-induced omphalocele in the chick model. 22nd Congress of Asian Association of Pediatric Surgeons (Kuala Lumpur, Malaysia) 20-24, Feb, 2010 [10min Oral Presentation in Award Session]

20) Doi T, Lukošiūtė A, Ruttenstock E, Dingemann J and Puri P: Expression of iroquois genes is upregulated during early lung development in the nitrofen induced pulmonary hypoplasia. American Pediatric Surgical Association (Orlando, FL, USA) 16-19, May, 2010 [3min Oral/Poster Presentation]

21) Doi T, Thompson J, Bannigan J and Puri P: Epigenetic effect of cadmium on de novo dna hypomethylation in the cadmium-induced omphalocele in the chick model
Annual Meeting of European Paediatric Surgeon’s Association (Bern, Switzerland) 2-5, June, 2010 [10min Oral Presentation in Young Investigator Award Session]

22) Doi T, Thompson J, Bannigan J and Puri P:
failure of interaction of iqgap1 with rho-family gtpases in the cadmium-induced omphalocele in the chick model. Annual Congress of British Association of Paediatric Surgeons (Aberdeen, Scotland) 22-24 July, 2010 [10min Oral Presentation in Peter Paul Rickham Prize Session]

23) Doi T, Thompson J, Bannigan J and Puri P: Pre-treatment with n-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation in Aesculap Prize Session]

24) Doi T, Dingemann J, Ruttenstock E and Puri P:
Expression of the wilm’s tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation in Aesculap Prize Session]

25) Doi T, Thompson J, Bannigan J and Puri P: Disruption of GLI3-ZIC3 interaction in the cadmium-induced omphalocele in the chick model. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation]

26) Doi T, Shintaku M, Ruttenstock E, Dingemann J and Puri P: Downregulation of midkine gene expression and its response to retinoic acid treatment in the nitrofen-induced hypoplastic lung. International Symposium on Paediatric Surgical Research (Tokyo, Japan) 12-14 Sep, 2010 [6min Oral Presentation]

27) Doi T, Thompson J, Bannigan J and Puri P: BMPR1A-mediated BMP1 signalling is disrupted in the cadmium-induced omphalocele in the chick model.3rd World Congress of Pediatric Surgery (New Delhi, India) 21-24 Oct, 2010 [6min Oral Presentation]

28) Doi T, Thompson J, Bannigan J and Puri P: Altered PITX2 and LEF1 gene expression in the cadmium-induced omphalocele in the chick model.3rd World Congress of Pediatric Surgery (New Delhi, India) 21-24 Oct, 2010 [6min Oral Presentation]

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土井 崇（ドイ タカシ）

土井崇（ドイタカシ）