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研究業績詳細

坂本 一博（サカモト カズヒロ）

研究テーマ Minimally invasive surgery, Chemotherapy and chemo-radiation therapy Colorectal cancer, Circulating
研究業績（論文） 1. Kawai M, Komiyama H, Hosoya M, Okubo H, Fujii T, Yokoyama N, Sato C, Ueyama T, Okuzawa A, Goto M, Kojima Y, Takahashi M, Sugimoto K, Ishiyama S, Munakata S, Ogura D, Niwa SI, Tomiki Y, Ochiai T, Sakamoto K.
Impact of chromosome 17q deletion in the primary lesion of colorectal cancer on liver metastasis.
Oncol Lett. 2016 Dec;12(6):4773-4778. doi: 10.3892/ol.2016.5271. Epub 2016 Oct 17.
Oncol Lett. 2016 Dec;12(6):4773-4778. doi: 10.3892/ol.2016.5271. Epub 2016 Oct 17.
2. Honjo K, Munakata S, Tashiro Y, Salama Y, Shimazu H, Eiamboonsert S, Dhahri D, Ichimura A, Dan T, Miyata T, Takeda K, Sakamoto K, Hattori K, Heissig B.
Plasuminogen acticator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice.
FASEB J 2017 Mar 7. pii: fj.201600871RR. doi: 10.1096/fj.201600871RR.
2017 Jun;31(6):2625-2637. doi: 10.1096/fj.201600871RR. Epub 2017 Mar 7.
3. Tanaka K, Okuda J, Yamamoto S, Ito M, Sakamoto K, Kokuba Y, Yoshimura K, Watanabe M.
Risk factors for anastomotic leakage after laparoscopic surgery with the double stapling technique for stage 0/I rectal carcinoma: a subgroup analysis of a multicenter, single-arm phase II trial. Surg Today. 2017 47(10):1215-1222. doi: 10.1007/s00595-017-1496-8. Epub 2017 Mar 9. PMID:28280982

4. Ito S, Koso H, Sakamoto K, Watanabe S.
RNA helicase DHX15 acts as a tumour suppressor in glioma.
Br J Cancer. 2017 Aug 22. doi: 10.1038/bjc.2017.273. [Epub ahead of print]
5. Sugimoto K, Sakamoto K, Ichikawa R, Kure K, Honjo K, Ro H, Takahashi R, Kawano S, Niwa K, Ishikaya S, Kamiyama H, Komiyama H, Takahashi M, Kojima Y, Goto M,
Ishibiki Y, Tomiki Y.
Propensity Score Analysis in the comparison of long-term outcomes for locally advanced colon cancer between laparoscopic colectomy and open colectomy.
Juntendo Medical Journal 2017 63(4). 264-272
6. Munakata S, Ito S, Kojima Y, Goto M, Tomiki Y, Sakamoto K.
Defunctioning loop ileostomy with restorative proctocolectomy for rectal cancer:
Friend or foe?
J Anus Rectum Colon 2017; 1(4): 136-140
dx.doi.org/10.23922/jarc.2017-023 http://journal-arc.jp
7. Munakata S, Sugimoto K, Honjo K, Kawai M, Kawano S, Kamiyama H, Ouchi M, Takahashi M, Tomiki Y, Sakamoto K
Neutrophil-Lymphocyte Ratio as a Prognostic Factor in Incurable Stage IV Colorectal Cancer
Open Journal of Gastroenterology(OJGas) 2018 DOI: 10.4236/ojgas.2018.82005
8. Ouchi M, Fukunaga M, Nagakari M, Azuma D, Kohama S, Nomoto J, Sakamoto K. Surgical technique and outcomes of transabdominal preperitoneal inguinal hernia repair after radical prostatectomy: dissection between the transversalis fascia and superficial layers of preperitoneal fascia Hernia 2018 https://doi.org/10.1007/s10029-018-1800-6
9．Honjo K, Kure K, Ro H, Mizukoshi K, Kawai M, Ishiyama S, Takahashi M, Tomiki Y, Sakamoto K.
Rectal neuroendocrine tumours treated using endoscopic submucosal dissection with myectomy; a video vignette.
Colorectal Disease 2018, 20; 1055-1056.
10. Takahashi M, Niitsu H, Sakamoto K, Hinoi T, Hattori M, Goto M, Bando H, Hazama S, Maeda K, Okita K, Horie H, Watanabe M;
Survival benefit of lymph node dissection in surgery for colon cancer in elderly patients: A multicenter propensity score-matched study in Japan.
Japan Society of Laparoscopic Colorectal Surgery. Asian J Endosc Surg. 2018 Nov;11(4):346-354. doi: 10.1111/ases.12474. Epub 2018 Mar 30.PMID: 29601663
11. Munakata S, Sakamoto K, Honjo K, Kawai M, Sugimoto K, Ouchi M, Takahashi M, Kojima Y, Nagakari K, Tomiki Y
Impact of Chylous Ascites on Colon Cancer in Laparoscopic Surgery
Open Journal of Gastroenterology 2018, 8, 269-274
12. Ohuchi M, Inaki N, Nagakari K, Kohama S, Sakamoto K, Ishizaki Y.
Transabdominal preperitoneal repair using barbed sutures for bilateral inguinal hernia in liver cirrhosis with ascites.
J Surg Case Rep. 2019 Feb;23(1):167-174. doi: 10.1007/s10029-018-1800-6. Epub 2018 Jul 25.
13. Sugimoto K, Ito T, Hulbert A, Chen C, Orita H, Maeda M, Moro H, Fukagawa T, Ushijima T, Katai H, Wada R, Sato K, Sakamoto K, Yu W, Considine M, Cope L, Brock MV.
DNA methylation genome-wide analysis in remnant and primary gastric cancers.
Gastric Cancer. 2019 Nov;22(6):1109-1120. doi: 10.1007/s10120-019-00949-5.
14. Yoshida Y, Yamada T, Matsuoka H, Sonoda H, Fukazawa A, Yoshida H, Ishida H, Hirata K, Hasegawa S, Sakamoto K, Otsuka T, Koda K.
A Trial Protocol of Biweekly TAS-102 and Bevacizumab as Third-Line Chemotherapy for Advanced/Recurrent Colorectal Cancer: A Phase II Multicenter Clinical Trial (The TAS-CC4 Study).
J Anus Rectum Colon. 2019 Jul 30;3(3):136-141. doi: 10.23922/jarc.2018-043. eCollection 2019. PMID:31583329
15. Takahashi R, Sakamoto K, Sugimoto K, Motegi S, Tsukamoto R, Ichikawa R,
Okazawa Y, Aoki J, Ishiyama S, Takahashi M, Kojima Y, Okuzawa A, Tomiki Y,
Masuoka J.
Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer
Dis Markers. 2019 Dec 14;2019:2721876. doi: 10.1155/2019/2721876. eCollection 2019.
16. Aoki J, Sakamoto K, Takahashi R, Niwa K, Ishiyama S, Sugimoto K, Kamiyama H, Takahashi M, Kojima Y, Goto M, Tomiki Y, Iba T
Current status of venous thromboembolism development during the perioperative period for colorectal cancer, its prevention with enoxaparin, and monitoring methods.
Ther Clin Risk Manag. 2019 Jun 21;15:791-802. doi: 10.2147/TCRM.S201954. eCollection 2019. PMID: 31417266
17. Makino Y, Munakata S, Ueyama T, Honjo K, Kawano S, Takahashi M, Kojima Y, Tomiki Y, Sakamoto K.
Effects of Receptor for Advanced Glycation End-Products (RAGE) Signaling on Intestinal Ischemic Damage in Mice.
Eur Surg Res. 2019;60(5-6):239-247. doi: 10.1159/000504751. Epub 2020 Jan 8.
18. Mizukoshi K, Okazawa Y, Haeno H, Koyama Y, Sulidan K, Komiyama H, Saeki H, Ohtsuji N, Ito Y, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A.
Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state.
Int J Cancer. 2020 May 1;146(9):2547-2562. doi: 10.1002/ijc.32672.
19. Sugimoto K, Momose H, Ito T, Orita H, Sato K, Sakamoto K, Brock MV.
Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer.
J Vis Exp. 2020 Sep 18;(163). doi: 10.3791/61355.
20. Hara K, Io H, Wakabayashi K, Maeda T, Kanda R, Nakata J, Maeda K, Sengoku H, Machida M, Kojima K, Sakamoto K, Tomino Y, Suzuki Y.
Multicenter laparoscopic evaluation of the peritoneum in peritoneal dialysis patients.
Semin Dial. 2020 Mar;33(2):170-177. doi: 10.1111/sdi.12870. Epub 2020 Mar 17.
21. Tsuchiya Y, Munakata S, Tsukamoto R, Okazawa Y, Mizukoshi K, Sugimoto K,
Takahashi M, Tomiki YKY, Sakamoto K.
Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position.
BMC Surg. 2020 Jun 16;20(1):136. doi: 10.1186/s12893-020-00771-2.
22. Munakata S, Ueyama T, Ishihara H, Komiyama H, Tsukamoto R, Kawai M, Takahashi
M, Kojima Y, Tomiki Y, Sakamoto K.
Angiopoietin-2 as a Prognostic Factor in Patients with Incurable Stage IV Colorectal Cancer.
J Gastrointest Cancer. 2020 Mar 13. doi: 10.1007/s12029-020-00392-1. Online ahead of print.PMID: 32166589
23. Yoshida Y, Yamada T, Kamiyama H, Kosugi C, Ishibashi K, Yoshida H, Ishida H,
Yamaguchi S, Kuramochi H, Fukazawa A, Sonoda H, Yoshimatsu K, Matsuda A,
Hasegawa S, Sakamoto K, Otsuka T, Koda K; TAS CC3 Study Group.
Combination of TAS-102 and bevacizumab as third-line treatment for metastatic colorectal cancer: TAS-CC3 study.
Int J Clin Oncol. 2020 Oct 21. doi: 10.1007/s10147-020-01794-8.
24. Shiosaki J, Tiirikainen M, Peplowska K, Shaeffer D, Machida M, Sakamoto K,
Takahashi M, Kojima K, Machi J, Bryant-Greenwood P, Kuwada SK.
Serum micro-RNA Identifies Early Stage Colorectal Cancer in a Multi-Ethnic Population.
Asian Pac J Cancer Prev. 2020 Oct 1;21(10):3019-3026.
doi: 10.31557/APJCP.2020.21.10.3019.
25. Kojima Y, Sakamoto K, Tomiki Y, Mizukoshi K.
Experience in the use of a device to attach an anti-adhesion-absorption barrier film to the abdominal cavity in laparoscopic colorectal surgery.
J Minim Access Surg. 2020 Oct-Dec;16(4):449-450. doi: 10.4103/jmas.JMAS_226_19.
26. Okita K, Hara Y, Okura H, Hayashi H, Sasaki Y, Masuko S, Kitadai E, Masuko K,
Yoshimoto S, Hayashi N, Sugiura R, Endo Y, Okazaki S, Arai S, Yoshioka T,
Matsumoto T, Makino Y, Komiyama H, Sakamoto K, Masuko T.
Antitumor effects of novel mAbs against cationic amino acid transporter 1 (CAT1) on human CRC with amplified CAT1 gene.
Cancer Sci. 2020 Nov 19. doi: 10.1111/cas.14741.
27. Kure K, Hosoya M, Ueyama T, Fukaya M, Sugimoto K, Tomiki Y, Ohnaga T,
Sakamoto K, Komiyama H.
Using the polymeric circulating tumor cell chip to capture circulating tumor cells in blood samples of patients with colorectal cancer.
Oncol Lett. 2020 Mar;19(3):2286-2294. doi: 10.3892/ol.2020.11335. Epub 2020 Jan 23.
28. Nakayama M, Hamada C, Yokoyama K, Tanno Y, Matsuo N, Nakata J, Ishibashi Y,
Okuzawa A, Sakamoto K, Nara T, Kakuta T, Nangaku M, Yokoo T, Suzuki Y, Miyata T.
A disposable, ultra-fine endoscope for non-invasive, close examination of the intraluminal surface of the peritoneal dialysis catheter and peritoneal cavity.
Sci Rep. 2020 Oct 16;10(1):17565. doi: 10.1038/s41598-020-74129-2.
29. Sugimoto K, Momose H, Ito T, Orita H, Sato K, Sakamoto K, Brock MV.
Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer. J Vis Exp. 2020 Sep 18;(163). doi: 10.3791/61355. PMID: 33016948.
Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer - PubMed (nih.gov)
30. Yamaguchi T, Murata K, Shiota T, Takeyama H, Noura S, Sakamoto K, Suto T,
Takii Y, Nagasaki T, Takeda T, Fujii M, Kagawa Y, Mizushima T, Ohno Y, Yao T, Kishimoto M, Sugihara K; Study Group of Appendiceal Neoplasms in the JSCCR.
　Clinicopathological Characteristics of Low-Grade Appendiceal Mucinous Neoplasm.
Dig Surg. 2021 Mar 10:1-8. doi: 10.1159/000513973. Online ahead of print.PMID: 33691316
31. Yamada T, Endo H, Hasegawa H, Kimura T, Kakeji K, Koda K, Ishida H, Sakamoto K, Hirata K, Yamamoto H, Miyata M, Matsuda A, Yoshida H, Kitagawa Y.
Risk of emergency surgery for complicated appendicitis: Japanese nationwide study
Ann Gastroenterol Surg. 2021;5: 236–242. DOI: 10.1002/ags3.12408
32. Sugimoto K, Sakamoto K, Ii Y, Amemiya K, Sugo H, Ito T, Munakata S, Takahashi M, Kojima Y, Tomiki Y, Sato K, Saiura A, Kawasaki S.
Significance of postoperative adjuvant chemotherapy with an oxaliplatin-based regimen after simultaneous curative resection for colorectal cancer and synchronous colorectal liver metastasis: a propensity score matching analysis.
BMC Surg. 2021 Apr 9;21(1):188. doi: 10.1186/s12893-021-01193-4.PMID: 33836701
33. Ishiyama, S., Kissel, C., Guo, X., Howard, A., Saeki, H., Ito, T., SysaShah, P., Orita, H., Sakamoto, K., Gabrielson, K.
A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate.
J. Vis. Exp. (), e62139, doi:10.3791/62139 (2021).
34. Takahashi M, Sakamoto S, Irie T, Kawano S, Sugimoto K, Kojima Y, Nojiri S, Okuzawa A, Tomiki Y.
Laparoscopic Surgery Is Acceptable for Elderly Patients With Colorectal Cancer: A Propensity Score-matched Study
Anticancer Res 2021 May;41(5):2611-2615. doi: 10.21873/anticanres.15041.
35. Haraikawa M, Kudo H, Shibuya T, Kogure Y, Takase M, Inage H, Yokota T, Hanni Htun H, Tagaya E, Fan R, Houshito H, Taniguchi G, Sakamoto K, Nagahara A
Efficacy of CO₂Infusion for Preoperative Computed Tomographic Angiography with Computed Tomographic Colonography
Med Sci Monit. 2021 May 16;27:e931055. doi: 10.12659/MSM.931055.
36. Munakata S, Tohya M, Matsuzawa H, Tsuchiya Y, Amemiya K, Hagiwara T, Motooka D, Nakamura S, Sakamoto K, Watanabe S.
Analysis of appendectomy samples identified dysbiosis in acute appendicitis.
Biosci Microbiota Food Health. 2021;40(2):92-97. doi: 10.12938/bmfh.2020-051. Epub 2020 Nov 14.PMID: 33996365
37. Kuramochi H, Yamada T, Yoshida Y, Matsuda A, Kamiyama H, Kosugi C, Ishibashi K, Fukazawa A, Ihara K, Sonoda H, Yoshimatsu K, Yoshida H, Hasegawa S, Sakamoto K, Ishida H, Koda K; TAS CC3 Study Group.
The Pre-treatment Lymphocyte-to-Monocyte Ratio Predicts Efficacy in Metastatic Colorectal Cancer Treated With TAS-102 and Bevacizumab.
Anticancer Res. 2021 Jun;41(6):3131-3137.
doi: 10.21873/anticanres.15098.PMID: 34083307
38. Matsuzawa H, Munakata S, Kawai M, Sugimoto K, Kamiyama H, Takahashi M, Kojima Y, Sakamoto K.
Analysis of ileostomy stool samples reveals dysbiosis in patients with high-output stomas
Biosci Microbiota Food Health 2021;40(3):135-143.
doi: 10.12938/bmfh.2020-062. Epub 2021 Feb 17.

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