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研究業績詳細

八田 耕太郎(ハッタ コウタロウ)

研究テーマ 精神科救急、統合失調症急性期治療、せん妄の予測・予防・治療
研究業績(論文) Sadahiro R, Hatta K, Yamaguchi T, Masanori E, Matsuda Y, Ogawa A, Iwata Y, Tokoro A, Nakahara R, Hirayama T, Yanai Y, Ogawa Y, Kayano A, Ariyoshi K, Oyamada S, Uchitomi Y, Akechi T, Yamamoto N, Okita N, Yorikane E, Shimada K, Furukawa T, Hashimoto H, Maeda M, Sato T, Sekimoto A, Sasaki C, Saito E, Uezono Y, Matsuoka H. A multi-centre, double-blind, randomized, placebo-controlled trial to evaluate the effectiveness and safety of ramelteon for the prevention of postoperative delirium in elderly cancer patients: a study protocol for JORTC-PON2/J-SUPPORT2103/NCCH2103. Jpn J Clin Oncol. 2023 Jun 20:hyad061. doi: 10.1093/jjco/hyad061.


Kotaro Hatta, Chie Usui, Hiroyuki Nakamura. Acceptability of transdermal antipsychotic patches by patients who refuse oral medication and their effectiveness in preventing recurrence of delirium: a retrospective observational study. Int Clin Psychopharmacol. 2023 Jan 1;38(1):23-27. doi: 10.1097/YIC.0000000000000428.

Ogawa T, Castelo-Branco L, Hatta K, Usui C. Association Between Step Count Measured With a Smartphone App (Pain-Note) and Pain Level in Patients With Chronic Pain: Observational Study. JMIR Form Res. 2022 Apr 6;6(4):e23657. doi: 10.2196/23657.

Hatta K. Prevention of delirium via melatonin and orexin neurotransmission. Juntendo Medical Journal 2022;68(1):12-16.

Hiroyuki Noto, Yasuhiro Kambayashi, Akinori Hara, Hiromasa Tsujiguchi, Yohei Yamada, Haruki Nakamura, Thao Nguyen, Kotaro Hatta, Tatsuya Honma, Tadashi Konoshita, Hiroyuki Nakamura. Fasting Blood Interleukin-1β and Interleukin-6 Levels as Predictors of Agitation in Patients with Alzheimer's Disease. International Journal of Gerontology 2021;15(3):255~259.

Hatta K, Katayama S, Ishizuka T, Sudo Y, Nakamura M, Hasegawa H, Imai A, Morikawa F, Shimada T, Misawa F, Ozaki S, Fujita K, Watanabe H, Nakamura H, Sugiyama N; JAST study group. Real-world effectiveness of antipsychotic treatments in 1011 acutely hospitalized patients with schizophrenia: A one-year follow-up study. Asian J Psychiatr. 2022 Jan;67:102917. doi: 10.1016/j.ajp.2021.102917. Epub 2021 Nov 6. PMID: 34875558.

Hatta K. Delirium. In: Management of Sleep Disorders in Psychiatry, eds. Amit Chopra, Piyush Das, and Karl Doghramji. Oxford University Press, New York, 2020. ISBN: 9780190929671

Hatta K, Kishi Y, Wada K, Takeuchi T, Hashimoto N, Suda K, Taira T, Tsuchida K, Ohmori T, Akizuki N, Nishio Y, Nakanishi Y, Usui C, Kurata A, Horikawa N, Eguchi H, Ito S, Muto H, Nakamura H, Uchimura N, for the DELIRIA-J Group: Real-world effectiveness of ramelteon and suvorexant on delirium prevention in 967 patients with delirium risk factors. J Clin Psychiatry 81(1) 19m12865, 2020. doi: 10.4088/JCP.19m12865.

Usui C, Kirino E, Tanaka S, Inami R, Nishioka K, Hatta K, Nakajima T, Nishioka K, Inoue R: Music Intervention Reduces Persistent Fibromyalgia Pain and Alters Functional Connectivity Between the Insula and Default Mode Network. Pain Medicine 2020;21(8):1546-52.

Tachibana M, Hashimoto T, Tanaka M, Watanabe H, Sato Y, Takeuchi T, Terao T, Kimura S, Koyama A, Ebisawa S, Shizu Y, Nagase T, Hirakawa J, Hatta K, Nakazato M, Iyo M: Patterns in Psychiatrists’ Prescription of Valproate for Female Patients of Childbearing Age with Bipolar Disorder in Japan: A Questionnaire Survey. Frontiers in Psychiatry 2020;11:250.

Hatta K, Hasegawa H, Imai A, Sudo Y, Morikawa F, Katayama S, Watanabe H, Ishizuka T, Nakamura M, Misawa F, Fujita K, Ozaki S, Umeda K, Nakamura H, Sawa Y, Sugiyama N, for the JAST study group. Real-world effectiveness of antipsychotic monotherapy and polytherapy in 1543 patients with acute-phase schizophrenia. Asian Journal of Psychiatry 2019;40:82–87

Hatta K, Katayama S, Morikawa F, Imai A, Fujita K, Fujita A, Ishizuka T, Abe T, Sudo Y, Hashimoto K, Usui C, Nakamura H, Yamanouchi Y, Hirata T, for the JAST study group. A prospective naturalistic multicenter study on choice of parenteral medication in psychiatric emergency settings in Japan. Neuropsychopharmacology Reports 2018;00:1–7. https://doi.org/10.1002/npr2.12015

Hatta K, Sugiyama N, Ito H. Switching and augmentation strategies for antipsychotic medications in acute-phase schizophrenia: latest evidence and place in therapy. Therapeutic Advances in Psychopharmacology 2018; 8(6): 173–183

Hatta K, Kishi Y, Wada K, Takeuchi T, Ito S, Kurata A, Murakami K, Sugita M, Usui C, Nakamura H, for the DELIRIA-J Group. Preventive effects of suvorexant on delirium: a randomized placebo-controlled trial. J Clin Psychiatry 2017 Sep/Oct;78(8):e970-e979.

Usui C, Soma T, Hatta K, Aratani S, Fujita H, Nishioka K, Machida Y, Kuroiwa Y, Nakajima T, Nishioka K. A Study of Brain Metabolism in Fibromyalgia by Positron Emission Tomography. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2017;75:120-127.

Hatta K. Antipsychotic adjunctive therapy to mood stabilizer should be continued for 6 months after remission of a manic episode. Evidence-Based Mental Health. (Evid Based Ment Health.) 2017 Feb;20(1):28.

Okumura Y, Hatta K, Wada K, Takeuchi T, Kishi Y, DELIRIA-J Group: Expert opinions on the first-line pharmacological treatment for delirium in Japan: A conjoint analysis. International Psychogeriatrics 2016 Jun;28(6):1041-50.

Komatsu T, Nomura T, Takami H, Sakamoto S, Mizuno K, Sekii H, Hatta K, Sugita M. Catatonic symptoms appearing before autonomic symptoms help distinguish neuroleptic malignant syndrome from malignant catatonia. Internal Medicine 55: 2893-2897, 2016

Hori D, Tsujiguchi H, Kambayashi Y, Hamagishi T, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Anyenda EO, Nguyen TT, Hibino Y, Shibata A, Hayashi K, Sagara T, Sasahara S, Matsuzaki I, Hatta K, Konoshita T, Nakamura H. The associations between lifestyles and mental health using the General Health Questionnaire 12-items are different dependently on age and sex: a population-based cross-sectional study in Kanazawa, Japan. Environ Health Prev Med. 2016;21(6):410-421.

Hamagishi T, Inagawa T, Kambayashi Y, Tsujiguchi H, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Hori D, Anyenda EO, Thao NTT, Hibino Y, Hayashi K, Shibata A, Sagara T, Okochi J, Takamoku K, Hatta K, Konoshita T, Nakamura H. The association between activity of daily living and the combination of Alzheimer’s disease and cataract in elderly requiring nursing care. Health 2016;8(10):994-1003 DOI: 10.4236/health.2016.810103

Hatta K, Kishi Y, Wada K: Ramelteon for delirium in hospitalized patients. JAMA 314: 1071-1072, 2015

Samara MT, Leucht C, Leeflang MM, Anghelescu I, Ascher-Svanum H, Chung Y, Crespo-Facorro B, Elkis H, Hatta K, Giegling I, Kane JM, Kayo M, Lambert M, Lin C, Möller H, Pelayo-Teran JM, Riedel M, Serretti A, Zhao JJ, Correll CU, Leucht S. Early improvement predicts later response to antipsychotics in schizophrenia: a diagnostic test review. The American Journal of Psychiatry 2015 Jul 1;172(7):617-29

Hatta K. Practical pharmacotherapy for acute schizophrenia patients. Psychiatry Clin Neurosci 69: 674-685, 2015

Hatta K, Kishi Y, Wada K, Takeuchi T, Odawara T, Usui C, Nakamura H, for the DELIRIA-J Group. Preventive effects of ramelteon on delirium: a randomized placebo-controlled trial. JAMA Psychiatry 2014;71(4):397-403

Hatta K, Otachi T, Fujita K, Morikawa F, Ito S, Tomiyama H, Abe T, Sudo Y, Takebayashi H, Yamashita T, Katayama S, Nakase R, Shirai Y, Usui C, Nakamura H, Ito H, Hirata T, Sawa Y, for the JAST study group. Antipsychotic switching versus augmentation among early non-responders to risperidone or olanzapine in acute-phase schizophrenia. Schizophrenia Research 158 (2014) 213–222

Hatta K, Kishi Y, Takeuchi T, Wada K, Odawara T, Usui C, Machida Y, Nakamura H, for the DELIRIA-J Group. The predictive value of a change in natural killer cell activity for delirium. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2014; 48: 26–31

Hatta K, Kishi Y, Wada K, Odawara T, Takeuchi T, Shiganami T, Tsuchida K, Oshima Y, Uchimura N, Akaho R, Watanabe A, Taira T, Nishimura K, Hashimoto N, Usui C, Nakamura H: Antipsychotics for delirium in the general hospital setting in consecutive 2,453 inpatients: a prospective observational study. International Journal of Geriatric Psychiatry 2014; 29(3): 253–262

Hatta K, Ito H: Strategies for early non-response to antipsychotic drugs in the treatment of acute-phase schizophrenia. Clinical Psychopharmacology and Neuroscience 2014 Apr; 12(1): 1-7

Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K. Vulnerability to traumatic stress in fibromyalgia patients: 19 months follow-up after the Great East Japan Disaster. Arthritis Research & Therapy 2013 Sep 23;15(5):R130

Hatta K, Takebayashi H, Sudo Y, Katayama S, Kasuya M, Shirai Y, Morikawa F, Nakase R, Nakamura M, Ito S, Kuga H, Nakamura M, Ohnuma T, Usui C, Nakamura H, Hirata T, Sawa Y, for the JAST study group. The possibility that requiring high-dose olanzapine cannot be explained by pharmacokinetics in the treatment of acute-phase schizophrenia. Psychiatry Research 2013; 210: 396–401

Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Ito K, Yamano Y, Nakamura H, Nakajima T, Nishioka K: The Japanese version of the modified ACR Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale: reliability and validity. Modern Rheumatology 2013 Sep;23(5):846-50

Honma T, Hatta K, Hitomi Y, Kambayash Y, Hibino Y, Konoshita T, Nakamura H. Increased systemic inflammatory interleukin-1s and interleukin-6 during agitation as predictors of Alzheimer disease. International Journal of Geriatric Psychiatry 2013 Mar;28(3):233-41

Hatta K, Otachi T, Sudo Y, et al: Difference in early prediction of antipsychotic non-response between risperidone and olanzapine in the treatment of acute-phase schizophrenia. Schizophrenia Research 128: 127-135, 2011

Hatta K, Sato K, Hamakawa H, et al: Effectiveness of second-generation antipsychotics with acute-phase schizophrenia. Schizophr Res 113: 49-55, 2009

Hatta K, Takahashi T, Nakamura H, et al: The association between intravenous haloperidol and prolonged QT interval. J Clin Psychopharmacol 21: 257-61, 2001

Hatta K, Takahashi T, Nakamura H, et al: Abnormal physiological conditions in acute schizophrenic patients on emergency admission: dehydration, hypokalemia, leukocytosis and elevated serum muscle enzymes. Eur Arch Psychiatry Clin Neurosci 248: 180-188, 1998

Hatta K, Miura Y, Asukai N, Hamabe Y: Amnesia from sarin poisoning. Lancet 347: 1343, 1996

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