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研究業績詳細

鈴木 香(スズキ カオリ)

研究テーマ 血管を場とした細胞間コミュニケーション
研究業績(論文) 原著論文
1. Watanabe N, Tanaka M, Suzuki K, Kumanogoh A, Kikutani H, Miyajima A: Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation. Hepatology 45: 1240-1249, 2007.
2. Nonaka H, Tanaka M, Suzuki K, Miyajima A: Development of murine hepatic sinusoidal endothelial cells characterized by the expression of hyaluronan receptors. Dev Dyn 236: 2258-2267, 2007.
3. Suzuki K, Tanaka M, Watanabe N, Saito S, Nonaka H, Miyajima A: p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver. Gastroenterology 135: 270-281, 2008.
4. Okabe M, Tsukahara Y, Tanaka M, Suzuki K, Saito S, Kamiya Y, Tsujimura T, Nakamura K, Miyajima A: Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver. Development 136: 1951-1960, 2009.
5. Tanaka M, Okabe M, Suzuki K, Kamiya Y, Tsukahara Y, Saito S, Miyajima A: Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK; drastic change of EpCAM expression during liver development. Mec Dev 126: 665-676, 2009.
6. Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M: Evaluation of the effect of α-defensins human neutrophil peptides on neutrophil apoptosis. Int J Mol Med 26: 925-934, 2010.
7. Murakami T, Suzuki K, Tamura H, Nagaoka I: Suppressive actions of resolvin D1 on the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. Exp Ther Med 2: 57-61, 2011.
8. Suzuki K, Murakami T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I: Human antimicrobial cathelicidin peptide LL-37 suppresses the lipopolysaccharide-induced apoptosis of endothelial cells. Int Immunol 23: 185-193, 2011.
9. Nagaoka I, Suzuki K, Niyonsaba F, Tamura H, Hirata M: Modulation of neutrophil apoptosis by antimicrobial peptides. ISRN Microbiol, Article ID 345791, 2012.
10. Murakami. T, Suzuki K, Tamura H, Nagaoka I: Suppressive actions of resolvin D1 on the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. Exp Ther Med 2: 57-61, 2011.
11. Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I: Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism. PLOS ONE 9(1): e85765. doi:10.1371/journal.pone.00857652, 2014.
12. Kido T, Koui Y, Suzuki K, Kobayashi A, Miura Y, Chern EY, Tanaka M, Miyajima A: CPM is a useful cell surface marker to isolate expandable bi-potential liver progenitor cells derived from human iPS cells. Stem Cell Reports 5: 508-15, 2015.
13. Suzuki K, Murakami T, Hu Z, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I: Human host defense cathelicidin peptide LL-37 enhances the LPS uptake by liver sinusoidal endothelial cells without cell activation. J Immunol 196: 1338-1347, 2016
14: Hu Z, Murakami T, Suzuki K, Tamura H, Reigh J, Kuwahara-Arai k, Iba T, Nagaoka I: Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice. Int Immunol 28: 245-253, 2016.
15: Hashiguchi M, Suzuki K, Kaneko K, Nagaoka I: Evaluation of the effect of aloe-emodin on the proliferation and apoptosis of human synovial MH7A cells; a comparison with methotrexate. Mol. Med. Reports 15: 4398-4404, 2017.
16. Murakami T, Suzuki K, Niyonsaba F, Tada H, Reich J, Tamura H, Nagaoka I: MrgX2-mediated internalization of LL-37 and degranulation of human LAD2 mast cells. Mol Med Rep 18: 4951-4959, 2018.
17. Suzuki K Ohkuma M, Nagaoka I: Bacterial lipopolysaccharide and antimicrobial LL-37 enhance ICAM-1 expression and NF-κB p65 phosphorylation in senescent endothelial cells. Int J Mol Med 44: 1187-1196, 2019.
18. Suzuki K, Ohkuma M, Someya A, Mita T, Nagaoka I: Cathelicidin peptide LL-37 induces cell death in autophagy-dysfunctional endothelial cells. J Immunol 280: 2163-2172, 2022.
19. Obata H, Naito K, Kikui A, Nakamura S, Suzuki K, Kawakita So, Suzuki T, Goto K, Nagura N, Sugiyama Y, Nagaoka I, Ishijima M: Age-related differences for the nerve-specific protein expression after peripheral nerve injury. Exp Ther Med 24: 682, 2022.

総説
1. Suzuki K, Nagaoka I: Effect of antimicrobial cathelicidin peptides on the endothelial cell apoptosis. Inflamm Regener 31: 375-381, 2011.
2. 鈴木 香, 村上泰介, 田村弘志, 長岡 功: エンドトキシンショックにおける微小血管内皮細胞のアポトーシスに対するヒト抗菌ペプチドLL-37の効果. 日本血流血管学会誌3: 30-33, 2011.
3. Nagaoka I, Suzuki K, Niyonsaba F, Tamura H, Hirata M: Modulation of neutrophil apoptosis by antimicrobial peptides. ISRN Microbiology, Volume 2012, Article ID 345791, 12 pages, 2012. (doi:10.5402/2012/345791)
4. 長岡 功, 胡 忠双, 鈴木 香, 田村弘志: 抗菌ペプチドによる敗血症ショックの制御. 化学療法の領域 30: 615-623, 2014.
5. Suzuki K, Nagaoka I: The Effects of the Human Host Defense Peptide LL-37 on Endothelial Cells. Juntendo Med J 62: 105-111, 2016.
6. 鈴木 香, 村上泰介, 胡 忠双, 長岡 功: 肝類洞内皮細胞の血液浄化作用に対するヒト生体防御ペプチドLL-37の効果 -エンドトキシン除去作用に着目して- 日本血管血流学会誌 1: 2016.
7. Suzuki K, Susaki EA, Nagaoka I: Lipopolysaccharides and cellular senescence: involvement in atherosclerosis. Int J Mol Sci 23: 11148, 2022.

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