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研究業績詳細
平井 誠（ヒライ マコト）
| 研究テーマ | マラリア原虫の生物学深化を基盤とした薬剤耐性メカニズムおよび生殖機構の解明 |
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| 研究業績（論文） | Hirai M, Maeta A, Mori T, Mita T. Pb103 Regulates Zygote/Ookinete Development in Plasmodium berghei via Double Zinc Finger Domains. Pathogens. 2021 Nov 24;10(12):1536. doi: 10.3390/pathogens10121536. PMID: 34959491; PMCID: PMC8707419. Yamauchi M, Hirai M, Tachibana SI, Mori T, Mita T. Fitness of sulfadoxine-resistant Plasmodium berghei harboring a single mutation in dihydropteroate synthase (DHPS). Acta Trop. 2021 Oct;222:106049. doi: 10.1016/j.actatropica.2021.106049. Epub 2021 Jul 15. PMID: 34273314. Ikeda M, Hirai M, Tachibana SI, Mori T, Mita T. Isolation of Mutants With Reduced Susceptibility to Piperaquine From a Mutator of the Rodent Malaria Parasite Plasmodium berghei. Front Cell Infect Microbiol. 2021 Jun 16;11:672691. doi: 10.3389/fcimb.2021.672691. PMID: 34222045; PMCID: PMC8242943. Kubo-Irie M, Hirai M, Irie M, Mohri H. Postulated Process of Axoneme Organization in the Male Gametogenesis of Malaria Parasite Plasmodium berghei. Zoolog Sci. 2021 Apr;38(2):187-192. doi: 10.2108/zs200064. PMID: 33812358. Balikagala B, Sakurai-Yatsushiro M, Tachibana SI, Ikeda M, Yamauchi M, Katuro OT, Ntege EH, Sekihara M, Fukuda N, Takahashi N, Yatsushiro S, Mori T, Hirai M, Opio W, Obwoya PS, Anywar DA, Auma MA, Palacpac NMQ, Tsuboi T, Odongo-Aginya EI, Kimura E, Ogwang M, Horii T, Mita T. Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern Uganda. Malar J. 2020 Feb 18;19(1):76. doi: 10.1186/s12936-020-03157-0. Mori T*, Hirai M, Mita T See-through observation of malaria parasite behaviors in the mosquito vector. Sci. Reports. 9(1):1768, 2019 Sekihara M, Tachibana SI, Yamauchi M, Yatsushiro S, Tiwara S, Fukuda N, Ikeda M, Mori T, Hirai M, Hombhanje F, Mita T*. Lack of significant recovery of chloroquine sensitivity in Plasmodium falciparum parasites following discontinuance of chloroquine use in Papua New Guinea. Malar J. 17(1):434, 2018 Ikeda M, Kaneko M, Tachibana SI, Balikagala B, Sakurai-Yatsushiro M, Yatsushiro S, Takahashi N, Yamauchi M, Sekihara M, Hashimoto M, Katuro OT, Olia A, Obwoya PS, Auma MA, Anywar DA, Odongo-Aginya EI, Okello-Onen J, Hirai M, Ohashi J, Palacpac NMQ, Kataoka M, Tsuboi T, Kimura E, Horii T, Mita T*. Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016. Emerg Infect Dis. 24(4):718-726, 2018 Honma H, Niikura M, Kobayashi F, Horii T, Mita T, Endo H, Hirai M*. Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase δ. Sci Rep. 6:36971, 2016. Ebine K, Hirai M, Sakaguchi M, Yahata K, Kaneko O, Saito-Nakano Y*. Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2. Malar J. 15:323, 2016. Taniguchi T, Miyauchi E, Nakamura S, Hirai M, Suzue K, Imai T, Nomura T, Handa T, Okada H, Shimokawa C, Onishi R, Olia A, Hirata J, Tomita H, Ohno H, Horii T, Hisaeda H* Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis. Sci. Reports 5:15699, 2015. Siregar JE, Kurisu G, Kobayashi T, Matsuzaki M, Sakamoto K, Mi-ichi F, Watanabe Y, Hirai M, Matsuoka H, Syafruddin D, Marzuki S, Kita K*. Direct evidence for the atovaquone action on the Plasmodium cytochrome bc1 complex. Parasitol Int. 64(3):295-300, 2015. Hikosaka K, Hirai M, Komatsuya K, Ono Y, Kita K* Lactate retards the development of erythrocytic stages of the human malaria parasite Plasmodium falciparum. Parasitol Int. 64(3):301-3, 2015. Mita T*, Tachibana S-I, ,Hashimoto M, Hirai M Plasmodium falciparum Kelch13: A potential molecular marker for tackling artemisinin-resistant malaria parasites. Expert Review of Anti-infective Therapy 14(1):125-35, 2016. Hirai M* and Mita T: Challenging Malaria Control: Do Our New Genetic Tools Pave the Way for Malaria Eradication? Juntendo Medical Journal 61 (4), 370-377, 2015 |
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