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研究業績詳細

陸 彦(ルー エン)

研究テーマ 前立腺がんにおけるAhr遺伝子の機能解析およびがん治療への応用研究
研究業績(論文) Chen S., Song W., Zhang R., Jin Y., Lu Y., Lin L., Ye L., Li T., Wei Y. Analysis of survival and prognostic factors of clear cell adenocarcinoma of the prostate: a case-control study for a rare cancer entity. Scientific Reports 2023;13(1):10317. Journal Article Analysis of survival and prognostic factors of clear cell adenocarcinoma of the prostate: a case-control study for a rare cancer entity 37365217

Kimura T., Kawano H., Muto S., Muramoto N., Takano T., Lu Y., Eguchi H., Wada H., Okazaki Y., Ide H., Horie S. PKD1 Mutation Is a Biomarker for Autosomal Dominant Polycystic Kidney Disease. Biomolecules 2023;13(7). Journal Article PKD1 Mutation Is a Biomarker for Autosomal Dominant Polycystic Kidney Disease 37509056

Wu W., Zhang R., Jin Y., Lu Y., Lu Z., Li T., Ye L., Lin L., Wei Y. Cancer trends and risk factors in China over the past 30 years (1990-2019). Journal of Cancer 2023;14(10):1935-1945. Journal Article Cancer trends and risk factors in China over the past 30 years (1990-2019) 37476192

Shirakawa T., Fink J., Hotta Z.U., Shimada Y., Lu Y., Du J., Matsushita K., Hori S., Ide H., Horie S. The impact of serum testosterone level to reflect age-related multi-organ functions. Endocrine Journal 2024. Journal Article The impact of serum testosterone level to reflect age-related multi-organ functions 38191198

Nakayama A., Ide H., Lu Y., Takei A., Fukuda K., Osaka A., Arai G., Horie S., Okada H., Saito K. Effects of Curcumin Combined With the 5-alpha Reductase Inhibitor Dutasteride on LNCaP Prostate Cancer Cells. In Vivo 2021;35(3):1443-1450. Journal Article Effects of Curcumin Combined With the 5-alpha Reductase Inhibitor Dutasteride on LNCaP Prostate Cancer Cells 33910821

Nagaya N., Lee G.T., Lu Y., Ashizawa T., Nagata M., Kim I.Y., Horie S. Transcription factor 4 expression in circulating tumor cells from castration-resistant prostate cancer. IJU Case Rep 2021;4(3):159-162. Journal Article
Transcription factor 4 expression in circulating tumor cells from castration-resistant prostate cancer 33977248

Muto S., Lu Y., Ide H., Yamaguchi R., Saito K., Kitamura K., Noma Y., Koyasu H., Hirano H., Ashizawa T., Isotani S., Nagata N., Horie S. The Use of Urine Mycobacterium tuberculosis Complex Polymerase Chain Reaction as a Predictive Factor for Recurrence and Progression After Intravesical Bacillus Calmette-Guérin Therapy in Patients with Non–muscle‑invasive Bladder Cancer. European Urology Open Science 2021;27:10-18. Journal Article The Use of Urine Mycobacterium tuberculosis Complex Polymerase Chain Reaction as a Predictive Factor for Recurrence and Progression After Intravesical Bacillus Calmette-Guérin Therapy in Patients with Non–muscle‑invasive Bladder Cancer

Yu J., Lu Y., Muto S., Ide H., Horie S. The Dual Function of Aryl Hydrocarbon Receptor in Bladder Carcinogenesis. Anticancer Res 2020;40(3):1345-1357. Journal Article The Dual Function of Aryl Hydrocarbon Receptor in Bladder Carcinogenesis 32132031

Nagaya N., Nagata M., Lu Y., Kanayama M., Hou Q., Hotta Z.U., China T., Kitamura K., Matsushita K., Isotani S., Muto S., Sakamoto Y., Horie S. Prostate-specific membrane antigen in circulating tumor cells is a new poor prognostic marker for castration-resistant prostate cancer. PLoS One 2020;15(1):e0226219. Journal Article Prostate-specific membrane antigen in circulating tumor cells is a new poor prognostic marker for castration-resistant prostate cancer 31986176

Hirano H., Ide H., Lu Y., Inoue Y., Okada H., Horie S. Impact of Pretreatment Total Cholesterol Level Is Associated With Metastasis of Prostate Cancer. Am J Mens Health 2020;14(2):1557988320918788. Journal Article Impact of Pretreatment Total Cholesterol Level Is Associated With Metastasis of Prostate Cancer 32349610

De Velasco M.A., Lu Y., Kura Y., China T., Inoue Y., Nakayama A., Okada H., Horie S., Uemura H., Ide H. Chemopreventive effects of nanoparticle curcumin in a mouse model of Pten-deficient prostate cancer. Hum Cell 2020;33(3):730-736. Journal Article Chemopreventive effects of nanoparticle curcumin in a mouse model of Pten-deficient prostate cancer 32146706

Inoue Y., Nakamura K., Kuwahara Y., Lu Y., Masuda N., Horie S., Okada H., Ide H. Efficacy of Testosterone Treatment in Hemodialysis Patients as Assessed by Aging Males' Symptoms Scores: A Pilot Study. Am J Mens Health 2018;12(5):1541-1547. Journal Article Efficacy of Testosterone Treatment in Hemodialysis Patients as Assessed by Aging Males' Symptoms Scores: A Pilot Study 29720027

Ide H., Lu Y., Ono M., Tokairin T., Okada H., Horie S. Intra-adrenal corticotropin in bilateral macronodular adrenal hyperplasia: Report of two Japanese cases. Int J Urol 2018;25(3):307-308. Journal Article Intra-adrenal corticotropin in bilateral macronodular adrenal hyperplasia: Report of two Japanese cases 29268306

Ide H., Lu Y., Noguchi T., Muto S., Okada H., Kawato S., Horie S. Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer. Cancer Sci 2018;109(4):1230-1238. Journal Article Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer 29369461

Hou Q., Bing Z.T., Hu C., Li M.Y., Yang K.H., Mo Z., Xie X.W., Liao J.L., Lu Y., Horie S., Lou M.W. RankProd Combined with Genetic Algorithm Optimized Artificial Neural Network Establishes a Diagnostic and Prognostic Prediction Model that Revealed C1QTNF3 as a Biomarker for Prostate Cancer. EBioMedicine 2018;32:234-244. Journal Article RankProd Combined with Genetic Algorithm Optimized Artificial Neural Network Establishes a Diagnostic and Prognostic Prediction Model that Revealed C1QTNF3 as a Biomarker for Prostate Cancer 29861410

Mizuno T H.I., Aoki Y, Shimoyama H, Nozaki T, Shirai M, Lu Y, Horie S, Tsujimura A. Relation between histological prostatitis and lower urinary tract symptoms and erectile function. Prostate International 2017;5(3):5. Journal Article Relation between histological prostatitis and lower urinary tract symptoms and erectile function

Ide H., Lu Y., Yu J., Noguchi T., Kanayama M., Muto S., Yamaguchi R., Kawato S., Horie S. Aryl hydrocarbon receptor signaling involved in the invasiveness of LNCaP cells. Hum Cell 2017;30(2):133-139. Journal Article Aryl hydrocarbon receptor signaling involved in the invasiveness of LNCaP cells 28093676

Nakajima A., Lu Y., Kawano H., Horie S., Muto S. Association of arginine vasopressin surrogate marker urinary copeptin with severity of autosomal dominant polycystic kidney disease (ADPKD). Clin Exp Nephrol 2015;19(6):1199-1205. Journal Article Association of arginine vasopressin surrogate marker urinary copeptin with severity of autosomal dominant polycystic kidney disease (ADPKD) 25715868

Kawano H., Muto S., Ohmoto Y., Iwata F., Fujiki H., Mori T., Yan L., Horie S. Exploring urinary biomarkers in autosomal dominant polycystic kidney disease. Clin Exp Nephrol 2015;19(5):968-973. Journal Article Exploring urinary biomarkers in autosomal dominant polycystic kidney disease 25543187

Ide H., Yamagishi S., Lu Y., Sakamaki K., Nakajima A., Horiuchi A., Kitamura K., Hisasue S., Muto S., Yamaguchi R., Horie S. Circulating pigment epithelium-derived factor (PEDF) is associated with pathological grade of prostate cancer. Anticancer Res 2015;35(3):1703-1708. Journal Article Circulating pigment epithelium-derived factor (PEDF) is associated with pathological grade of prostate cancer 25750331

Ide H., Lu Y., Tanaka T., Wakumoto Y., Kitamura K., Muto S., Yamaguchi R., Masumori N., Horie S. Circulating tumor cell count during zoledronic acid treatment in men with metastatic prostate cancer: a pilot study. Prostate Int 2014;2(3):147-151. Journal Article Circulating tumor cell count during zoledronic acid treatment in men with metastatic prostate cancer: a pilot study 25325027

Ide H., Terado Y., Sakamaki K., Inoue M., Nakajima A., Lu Y., Hisasue S., Yamaguchi R., Muto S., Horie S. Serum level of follicle-stimulating hormone is associated with extraprostatic extension of prostate cancer. Prostate Int 2013;1(3):109-112. Journal Article Serum level of follicle-stimulating hormone is associated with extraprostatic extension of prostate cancer 24223411

Ide H., Lu Y., Yu J., China T., Kumamoto T., Koseki T., Yamaguchi R., Muto S., Horie S. Testosterone promotes DNA damage response under oxidative stress in prostate cancer cell lines. Prostate 2012;72(13):1407-1411. Journal Article Testosterone promotes DNA damage response under oxidative stress in prostate cancer cell lines 22290195

Aoki H., Nagao J., Ueda T., Strong J.M., Schonlau F., Yu-Jing S., Lu Y., Horie S. Clinical assessment of a supplement of Pycnogenol(R) and L-arginine in Japanese patients with mild to moderate erectile dysfunction. Phytother Res 2012;26(2):204-207. Journal Article Clinical assessment of a supplement of Pycnogenol(R) and L-arginine in Japanese patients with mild to moderate erectile dysfunction 21618639

Ide H., Yu J., Lu Y., China T., Kumamoto T., Koseki T., Muto S., Horie S. Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP. Cancer Sci 2011;102(2):468-471. Journal Article Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP 21134073

Saitoh T., Iyoda S., Yamamoto S., Lu Y., Shimuta K., Ohnishi M., Terajima J., Watanabe H. Transcription of the ehx enterohemolysin gene is positively regulated by GrlA, a global regulator encoded within the locus of enterocyte effacement in enterohemorrhagic Escherichia coli. J Bacteriol 2008;190(14):4822-4830. Journal Article Transcription of the ehx enterohemolysin gene is positively regulated by GrlA, a global regulator encoded within the locus of enterocyte effacement in enterohemorrhagic Escherichia coli 18487325

Nakasone N., Toma C., Lu Y., Iwanaga M. Development of a rapid immunochromatographic test to identify enteropathogenic and enterohemorrhagic Escherichia coli by detecting EspB. Diagn Microbiol Infect Dis 2007;57(1):21-25. Journal Article Development of a rapid immunochromatographic test to identify enteropathogenic and enterohemorrhagic Escherichia coli by detecting EspB 16860514

Lu Y., Iyoda S., Satou H., Satou H., Itoh K., Saitoh T., Watanabe H. A new immunoglobulin-binding protein, EibG, is responsible for the chain-like adhesion phenotype of locus of enterocyte effacement-negative, shiga toxin-producing Escherichia coli. Infect Immun 2006;74(10):5747-5755. Journal Article A new immunoglobulin-binding protein, EibG, is responsible for the chain-like adhesion phenotype of locus of enterocyte effacement-negative, shiga toxin-producing Escherichia coli 16988252

Iyoda S., Koizumi N., Satou H., Lu Y., Saitoh T., Ohnishi M., Watanabe H. The GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli. J Bacteriol 2006;188(16):5682-5692. Journal Article The GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli 16885436

Toma C., Lu Y., Higa N., Nakasone N., Chinen I., Baschkier A., Rivas M., Iwanaga M. Multiplex PCR assay for identification of human diarrheagenic Escherichia coli. J Clin Microbiol 2003;41(6):2669-2671. Journal Article Multiplex PCR assay for identification of human diarrheagenic Escherichia coli 12791900

Lu Y., Toma C., Honma Y., Iwanaga M. Detection of EspB using reversed passive latex agglutination: application to determination of enteropathogenic Escherichia coli. Diagn Microbiol Infect Dis 2002;43(1):7-12. Journal Article Detection of EspB using reversed passive latex agglutination: application to determination of enteropathogenic Escherichia coli 12052623




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