学校法人順天堂　研究者情報データベース:::研究業績詳細:::

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研究業績詳細

南野徹（ミナミノトオル）

研究テーマ	循環器内科学
研究業績（論文）	1. Suda M, Shimizu I, Katsuumi G, Yoshida Y, Matsumoto N, Hayashi Y, Ikegami R, Yoshida Y, Mikawa R, Katayama A, Wada J, Seki M, Suzuki Y, Iwama A, Nakagami H, Nagasawa A, Morishita R, Sugimoto M, Okuda S, Tsuchida M, Ozaki K, Nakanishi-Matsui M, Minamino T. Senolytic vaccination improves pathological aging. Nat Aging. 2021 (in press). 2. Fukase T, Dohi T, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. Serum apolipoprotein E levels predict residual cardiovascular risk in patients with chronic coronary syndrome undergoing first percutaneous coronary intervention and on-statin treatment. Atherosclerosis. 2021 Aug 12;333:9-15. 3. Morisawa T, Saitoh M, Takahashi T, Watanabe H, Mochizuki M, Kitahara E, Fujiwara T, Fujiwara K, Nishitani-Yokoyama M, Minamino T, Shimada K, Honzawa A, Shimada A, Yamamoto T, Asai T, Amano A, Daida H. Association of phase angle with hospital-acquired functional decline in older patients undergoing cardiovascular surgery. Nutrition. 2021 Jun 26;91-92:111402. 4. Noguchi M, Dohi T, Okazaki S, Matsumura M, Takeuchi M, Endo H, Kato Y, Okai I, Nishiyama H, Doi S, Iwata H, Isoda K, Usui E, Fujimura T, Seike F, Mintz GS, Miyauchi K, Daida H, Minamino T, Maehara A. Comparison of 6-month vascular healing response after bioresorbable polymer versus durable polymer drug-eluting stent implantation in patients with acute coronary syndromes: A randomized serial optical coherence tomography study. Catheter Cardiovasc Interv. 2021 (in press) 5. Kaneko T, Kagiyama N, Nakamura Y, Hirasawa T, Murata A, Morimoto R, Miyazaki S, Minamino T. Effectiveness of real-time tele-ultrasound for echocardiography in resource-limited medical teams. J Echocardiogr. 2021 (in press) 6. Otsuki S, Izumi D, Sakaguchi Y, Suzuki N, Hakamata T, Ikami Y, Hasegawa Y, Yagihara N, Iijima K, Chinushi M, Minamino T, Takayuki I. Efficacy of antitachycardia pacing alert by remote monitoring of implantable cardioverter-defibrillators for out-of-hospital electrical storm. Pacing Clin Electrophysiol. 2021 (in press) 7. Shiozaki M, Sumiyoshi M, Tabuchi H, Hayashi H, Tamura H, Inoue K, Minamino T. A Case of J Wave Syndrome Due to Severe Hypercalcemia with Ventricular Fibrillation Storm and Successful Treatment of Isoproterenol Infusion. Int Heart J. 2021;62(4):924-926. 8. Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. High Apolipoprotein E Levels Predict Adverse Limb Events in Patients with Peripheral Artery Disease Due to Peripheral Artery Disease Undergoing Endovascular Treatment and On-Statin Treatment. Int Heart J. 2021 Jul 30;62(4):872-878. 9. Takeuchi M, Dohi T, Fukase T, Nishio R, Takahashi N, Endo H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. Comparison of clinical outcomes between percutaneous coronary intervention for de novo lesions versus in-stent restenosis lesions. Cardiovasc Interv Ther. 2021 (in press) 10. Fujiki S, Watanabe H, Obata H, Suda M, Mitsuma W, Tomii A, Sakai K, Uehara A, Shimizu I, Kashimura T, Ozaki K, Minamino T. Association of adipokines with frailty in heart failure. Acta Biomed. 2021 Jul 1;92(3):e2021195. 11. Nozaki YO, Fujimoto S, Aoshima C, Kamo Y, Kawaguchi YO, Takamura K, Kudo A, Takahashi D, Hiki M, Kato Y, Okai I, Dohi T, Okazaki S, Tomizawa N, Kumamaru KK, Aoki S, Minamino T. Comparison of diagnostic performance in on-site based CT-derived fractional flow reserve measurements. Int J Cardiol Heart Vasc. 2021 (in press) 12. Ishiwata S, Matsue Y, Nakamura Y, Dotare T, Sunayama T, Suda S, Yatsu S, Kato T, Hiki M, Kasai T, Minamino T. Clinical and prognostic values of urinary alpha1-microglobulin as a tubular marker in acute heart failure. Int J Cardiol. 2021 (in press) 13. Matsuo Y, Ozaki K, Ikegami R, Nishida K, Kubota N, Takano T, Okubo T, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Conservative treatment with an intra-aortic balloon pump to treat acute myocardial infarction due to spontaneous coronary artery dissection. J Cardiol Cases. 2021 Jan 30;23(6):274-280. 14. Nishitani-Yokoyama M, Shimada K, Yamada M, Honzawa A, Kunimoto M, Sugita Y, Fujiwara K, Matsubara T, Matsumori R, Abulimiti A, Shimada A, Yamamoto T, Asai T, Amano A, Saitoh M, Morisawa T, Takahashi T, Daida H, Minamino T. Association Between Constipation and Frailty Components in Patients Undergoing Late Phase II Cardiac Rehabilitation. Cardiol Res. 2021 Jun;12(3):169-176. 15. Takeuchi M, Wada H, Ogita M, Takahashi D, Okada-Nozaki Y, Nishio R, Yasuda K, Takahashi N, Sonoda T, Yatsu S, Shitara J, Tsuboi S, Dohi T, Suwa S, Miyauchi K, Daida H, Minamino T. Impact of Prior Stroke on Long-Term Outcomes in Patients With Acute Coronary Syndrome. Circ Rep. 2021 Apr 9;3(5):267-272. 16. Kagiyama N, Hiki M, Matsue Y, Dohi T, Matsuzawa W, Daida H, Minamino T, Kasai T. Validation of telemedicine-based self-assessment of vital signs for patients with COVID-19: A pilot study. J Telemed Telecare. 2021 (in press) 17. Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. Long-term impact of high-sensitivity C-reactive protein in patients with intermittent claudication due to peripheral artery disease following endovascular treatment. Heart Vessels. 2021 (in press) 18. Kubota N, Ozaki K, Tanabe Y, Iwasaki Y, Yoshida T, Okubo T, Kimura S, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Usefulness of Repeat Angiography to Establish Spontaneous Coronary Artery Dissection in Small Vessels. Circ Rep. 2020 Oct 29;2(12):739-743. 19. Hasegawa Y, Izumi D, Ikami Y, Otsuki S, Yagihara N, Iijima K, Chinushi M, Minamino T. Progressive increase in activation delay during premature stimulation is related to ventricular fibrillation in Brugada syndrome. J Cardiovasc Electrophysiol. 2021 (in press) 20. Ozaki K, Okubo T, Hagiya K, Kubota N, Tsuchida K, Takahashi K, Oda H, Minamino T. Unstable angina complicated with dynamic left ventricular outflow tract obstruction. J Cardiol Cases. 2021 Feb 12;23(4):181-188. 21. Hagiya K, Ozaki K, Nanasato M, Iguchi N, Takayama M, Shimokawa T, Tanabe N, Minamino T, Isobe M. Relationship Between Heart Rate at Discharge and Long-Term Outcomes of Surgically Treated Patients With Type A Acute Aortic Dissections. Circ J. 2021 (in press) 22. Hsiao YT, Shimizu I, Wakasugi T, Yoshida Y, Ikegami R, Hayashi Y, Suda M, Katsuumi G, Nakao M, Ozawa T, Izumi D, Kashimura T, Ozaki K, Soga T, Minamino T. Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy. Sci Rep. 2021 Mar 24;11(1):6722. 23. Takahashi N, Dohi T, Endo H, Takeuchi M, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. Coronary lipid-rich plaque characteristics in Japanese patients with acute coronary syndrome and stable angina: A near infrared spectroscopy and intravascular ultrasound study. Int J Cardiol Heart Vasc. 2021 Mar 11;33:100747. 24. Fujiwara K, Shimada K, Nishitani-Yokoyama M, Kunimoto M, Matsubara T, Matsumori R, Abulimiti A, Aikawa T, Ouchi S, Shimizu M, Fukao K, Miyazaki T, Honzawa A, Yamada M, Saitoh M, Morisawa T, Takahashi T, Daida H, Minamino T. Arterial Stiffness Index and Exercise Tolerance in Patients Undergoing Cardiac Rehabilitation. Int Heart J. 2021 Mar 30;62(2):230-237. 25. Fukuda K, Okazaki S, Shiozaki M, Okai I, Nishino A, Tamura H, Inoue K, Sumiyoshi M, Daida H, Minamino T. Ultrasound-guided puncture reduces bleeding-associated complications, regardless of calcified plaque, after endovascular treatment of femoropopliteal lesions, especially using the antegrade procedure: A single-center study. PLoS One. 2021 Mar 12;16(3):e0248416. 26. Abulimiti A, Nishitani-Yokoyama M, Shimada K, Kunimoto M, Matsubara T, Fujiwara K, Aikawa T, Ouchi S, Sugita Y, Fukao K, Kadoguchi T, Miyazaki T, Shimada A, Yamamoto T, Takahashi T, Fujiwara T, Asai T, Amano A, Daida H, Minamino T. Prognostic impact of peak oxygen uptake and heart rate reserve in patients after off-pump coronary artery bypass grafting. Clin Cardiol. 2021 Apr;44(4):580-587. 27. Takeuchi M, Dohi T, Takahashi N, Endo H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. The prognostic implications of chronic kidney disease and anemia on long-term outcomes in patients undergoing percutaneous coronary intervention. Heart Vessels. 2021 (in press) 28. Matsuo Y, Yoshimine F, Fuse K, Suzuki K, Sakamoto T, Iijima K, Ozaki K, Minamino T. Regional Disparities in Adherence to Guidelines for the Treatment of Chronic Heart Failure. Intern Med. 2021;60(4):525-532. 29. Minami-Takano A, Iwata H, Miyosawa K, Shiozawa T, Hayashi H, Funamizu T, Ishii K, Nozaki Y, Tabuchi H, Sekita G, Shimada K, Sumiyoshi M, Nakazato Y, Daida H, Minamino T. The association between impairment of HDL cholesterol efflux capacity and atrial remodeling in atrial fibrillation. Sci Rep. 2021 Feb 11;11(1):3547. 30. Hirose S, Matsue Y, Kamiya K, Kagiyama N, Hiki M, Dotare T, Sunayama T, Konishi M, Saito H, Saito K, Ogasahara Y, Maekawa E, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Momomura SI, Minamino T. Prevalence and prognostic implications of malnutrition as defined by GLIM criteria in elderly patients with heart failure. Clin Nutr. 2021 (in press) 31. Hasegawa Y, Watanabe H, Ikami Y, Otsuki S, Iijima K, Yagihara N, Izumi D, Minamino T. J point elevation in high precordial leads associated with risk of ventricular fibrillation. Ann Noninvasive Electrocardiol. 2020; e12820. 32. Chikata Y, Iwata H, Doi S, Funamizu T, Okazaki S, Dohi S, Higuchi R, Saji M, Takamisawa I, Tamura H, Amano A, Daida H, Minamino T. Simultaneous Estimation of Gender Male and Atrial Fibrillation as Risk Factors for Adverse Outcomes Following Transcatheter Aortic Valve Implantation. J Clin Med. 2020; 9(12): 3963. 33. Kato Y, Dohi T, Chikata Y, Fukase T, Takeuchi M, Takahashi N, Endo H, Nishiyama H, Doi S, Okai I, Iwata H, Isoda K, Okazaki S, Miyauchi K, Daida H, Minamino T. Predictors of discordance between fractional flow reserve and resting full-cycle ratio in patients with coronary artery disease: Evidence from clinical practice. J Cardiol. 2021 Mar;77(3):313-319. 34. Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. Long-term clinical outcomes and cause of death after endovascular treatment for femoropopliteal artery lesions. J Cardiol. 2021 Apr;77(4):417-423. 35. Honzawa A, Nishitani-Yokoyama M, Shimada K, Kunimoto M, Yamada M, Matsubara T, Matsumori R, Fujiwara K, Abulimiti A, Aikawa T, Ouchi S, Shimizu M, Sugita Y, Shimada A, Yamamoto T, Amano A, Asai T, Saito M, Morisawa T, Takahashi T, Fujiwara T, Daida H, Minamino T. Relationship Between Kihon Checklist Score and Anxiety Levels in Elderly Patients Undergoing Early Phase II Cardiac Rehabilitation. Cardiol Res. 2020; 11(6): 405-411. 36. Kubota N, Ozaki K, Hoyano M, Nishida K, Takano T, Okubo T, Kimura S, Yanagawa T, Kashimura T, Minamino T. Long-Term Prognosis of Patients Who Underwent Percutaneous Transvenous Mitral Commissurotomy for Mitral Stenosis. Int Heart J. 2020; 61(6): 1183-1187. 37. Sai E, Shimada K, Aikawa T, Aoshima C, Takamura K, Hiki M, Yokoyama T, Miyazaki T, Fujmoto S, Konishi H, Hirano KI, Daida H, Minamino T. Triglyceride Deposit Cardiomyovasculopathy with Massive Myocardial Triglyceride which was Proven Using Proton-magnetic Resonance Spectroscopy. Intern Med. 2021 Apr 15;60(8):1217-1220. 38. Kubota N, Ozaki K, Hakamata T, Ikami Y, Hoyano M, Minamino T. Angioscopic findings of organized thrombosis of iliac vein in patient with chronic thromboembolic pulmonary hypertension. Cardiovasc Interv Ther. 2020 (in press). 39. Kubota N, Ozaki K, Hoyano M, Minamino T. Angioscopic Findings of Deep Vein Thrombosis Treated by Balloon Angioplasty With Catheter-Directed Thrombolysis. Circ J. 2020; 84(12): 2320. 40. Miyosawa K, Iwata H, Minami-Takano A, Hayashi H, Tabuchi H, Sekita G, Kadoguchi T, Ishii K, Nozaki Y, Funamizu T, Chikata Y, Matsushita S, Amano A, Sumiyoshi M, Nakazato Y, Daida H, Minamino T. Enhanced monocyte migratory activity in the pathogenesis of structural remodeling in atrial fibrillation. PLoS One. 2020; 15(10): e0240540. 41. Fujiki S, Iijima K, Okabe M, Niwano S, Tsujita K, Naito S, Ando K, Kusano K, Kato R, Nitta J, Miura T, Mitsuhashi T, Kario K, Kondo Y, Ieda M, Hagiwara N, Murohara T, Takahashi K, Tomita H, Takeishi Y, Anzai T, Shimizu W, Watanabe M, Morino Y, Kato T, Tada H, Nakagawa Y, Yano M, Maemura K, Kimura T, Yoshida H, Ota K, Tanaka T, Kitamura N, Node K, Aizawa Y, Shimizu I, Izumi D, Ozaki K, Minamino T; EMPA-ICD investigators. Placebo-Controlled, Double-Blind Study of Empagliflozin (EMPA) and Implantable Cardioverter-Defibrillator (EMPA-ICD) in Patients with Type 2 Diabetes (T2DM): Rationale and Design. Diabetes Ther. 2020; 11(11): 2739-2755. 42. Shirakawa K, Endo J, Kataoka M, Katsumata Y, Anzai A, Moriyama H, Kitakata H, Hiraide T, Ko S, Goto S, Ichihara G, Fukuda K, Minamino T, Sano M. MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin-Producing Reparative Macrophages After Myocardial Infarction. J Am Heart Assoc. 2020; 9(18): e017071. 43. Kim HK, Ko TH, Song IS, Jeong YJ, Heo HJ, Jeong SH, Kim M, Park NM, Seo DY, Kha PT, Kim SW, Lee SR, Cho SW, Won JC, Youm JB, Ko KS, Rhee BD, Kim N, Cho KI, Shimizu I, Minamino T, Ha NC, Park YS, Nilius B, Han J. BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes. Life Sci Alliance. 2020; 3(9):e201900619. 44. Sakai R, Ozaki K, Yamaguchi Y, Kubota N, Takano T, Okubo T, Kimura S, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Pulmonary Artery Sarcoma Diagnosed Using an Endovascular Catheter Forceps Biopsy. Intern Med. 2020; 59(17): 2149-2153. 45. Tahara N, Dobashi H, Fukuda K, Funauchi M, Hatano M, Ikeda S, Joho S, Kihara Y, Kondo T, Matsushita M, Minamino T, Nakanishi N, Okano Y, Ozaki Y, Saji T, Sakai S, Tanabe N, Watanabe H, Yamada H, Yoshioka K, Hatta M, Sasayama S. Long-term treatment of pulmonary arterial hypertension with macitentan in Japanese patients. Curr Med Res Opin. 2020; 36(6): 921-928. 46. Takano T, Ozaki K, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Angioscopic findings during balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension Cardiovasc Interv Ther. 2020; 35(4): 421-422. 47. Sueta D, Tabata N, Ikeda S, Saito Y, Ozaki K, Sakata K, Matsumura T, Yamamoto-Ibusuki M, Murakami Y, Jodai T, Fukushima S, Yoshida N, Kamba T, Araki E, Iwase H, Fujii K, Ihn H, Kobayashi Y, Minamino T, Yamagishi M, Maemura K, Baba H, Matsui K, Tsujita K. Differential predictive factors for cardiovascular events in patients with or without cancer history. Medicine (Baltimore). 2019; 98(44): e17602. (IF=1.870, CI=1) 48. Mori Y, Yamawaki K, Ishiguro T, Yoshihara K, Ueda H, Sato A, Ohata H, Yoshida Y, Minamino T, Okamoto K, Enomoto T. ALDH-Dependent glycolytic activation mediates stemness and paclitaxel resistance in patient-derived spheroid models of uterine endometrial cancer. Stem Cell Reports. 2019; 13(4): 730-746. (IF=5.499, CI=0) 49. Okura Y, Ozaki K, Tanaka H, Takenouchi T, Sato N, Minamino T. The impending epidemic of cardiovascular diseases in patients with cancer in Japan. Circ J. 2019; 83: 2191-2202. (IF=3.025, CI=0) 50. Sato A, Hasegawa Y, Haniu H, Shiraishi S, Yagihara N, Iijima K, Izumi D, Minamino T. Replacement of an Implantable Cardioverter-Defibrillator (ICD) with a New Standard Subcutaneous ICD System in a Patient with Jervell and Lange-Nielsen Syndrome. Int Heart J. 2019; 60(5): 1206-1210. 51. Kim HK, Jeon J, Song IS, Heo HJ, Jeong SH, Long LT, Thu VT, Ko TH, Kim M, Kim N, Lee SR, Yang JS, Kang MS, Ahn JM, Cho JY, Ko KS, Rhee BD, Nilius B, Ha NC, Shimizu I, Minamino T, Cho KI, Park YS, Kim S, Han J. Tetrahydrobiopterin enhances mitochondrial biogenesis and cardiac contractility via stimulation of PGC1α signaling. Biochim Biophys Acta Mol Basis Dis. 2019; 1865: 165524. (IF=4.328, CI=0) 52. Okura Y, Takayama T, Ozaki K, Tanaka H, Kikuchi A, Saito T, Tanigawa T, Takii Y, Seki H, Takenouchi T, Chou T, Sato N, Tanabe N, Minamino T. Future projection of cancer patients with cardiovascular disease in Japan by the year 2039: a pilot study. Int J Clin Oncol. 2019; 24(8): 983-994. (IF=2.503, CI=2) 53. Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T. Prolyl isomerase Pin1 suppresses thermogenic programs in adipocytes by promoting degradation of transcriptional co-activator PRDM16. Cell Rep. 2019; 26: 3221-3230. (IF=7.815, CI=1) 54. Yokoyama M, Shimizu I, Nagasawa A, Yoshida Y, Katsuumi G, Wakasugi T, Hayashi Y, Ikegami R, Suda M, Ota Y, Okada S, Fruttiger M, Kobayashi Y, Tsuchida M, Kubota Y, Minamino T. p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia. J Mol Cell Cardiol. 2019; 129: 105-117. (IF=5.055, CI=7) 55. Wakasugi T, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Nakao M, Hoyano M, Kashimura T, Nakamura K, Ito H, Nojiri T, Soga T, Minamino T. Role of smooth muscle cell p53 in pulmonary arterial hypertension. PLoS One. 2019; 14: e0212889. (IF=2.776, CI=1) 56. Yoshida Y, Shimizu I, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Wakasugi T, Nakao M, Nakagami H, Morishita R, Minamino T. Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity. Sci Rep. 2019; 9: 3858. (IF=4.011, CI=0) 57. Hasegawa Y, Watanabe H, Ikami Y, Otsuki S, Iijima K, Yagihara N, Sato A, Izumi D, Minamino T. Early repolarization and risk of lone atrial fibrillation. J Cardiovasc Electrophysiol. 2019; 30: 565-568. (IF=2.910, CI=1) 58. Ikegami R, Shimizu I, Sato T, Yoshida Y, Hayashi Y, Suda Ma, Katsuumi G, Li J, Wakasugi T, Minokoshi Y, Okamoto S, Hinoi E, Nielsen S, Zenius Jespersen N, Scheele C, Soga T, Minamino T. Gamma-aminobutyric acid signaling in brown adipose tissue promotes systemic metabolic derangement in obesity. Cell Rep. 2018: 24: 2827-2837. (IF=7.815, CI=4) 59. Takano T, Tanaka K, Ozaki K, Sato A, Iijima K, Yanagawa T, Izumi D, Ozawa T, Fuse K, Sato M, Tanabe N, Minamino T. Clinical predictors of recurrent ventricular arrhythmias in secondary prevention implantable cardioverter defibrillator recipients with coronary artery disease-Lower left ventricular ejection fraction and incomplete revascularization. Circ J. 2018; 82: 3037-3043. (IF=3.025, CI=1) 60. Teratani T, Tomita K, Suzuki T, Furuhashi H, Irie R, Nishikawa M, Yamamoto J, Hibi T, Miura S, Minamino T, Oike Y, Hokari R, and Kanai T. Aortic carboxypeptidase–like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis. J Clin Invest. 2018; 128: 1581-1596. (IF=12.282, CI=7) 61. Otuki S, Izumi D, Suda M, Sato A, Hasegawa Y, Yagihara N, Iijima K, Chinushi M, Fuse I, Minamino T. Effects of direct oral anticoagulants at the peak phase, the trough phase, and after vascular injury. J Am Coll Cardiol. 2018; 71: 102-104. (IF=18.639, CI=4) 62. Si S, Nakajima-Takagi Y, Iga T, Tsuji M, Hou L, Oshima M, Koide S, Saraya A, Yamazaki S, Takubo K, Kubota Y, Minamino T, Iwama A. Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells. Exp Hematol. 2018; 63: 41-51. (IF=2.462, CI=4) 63. Furuuchi R, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Wakasugi T, Nakao M, Minamino T. Boysenberry polyphenol inhibits endothelial dysfunction and improves vascular health. PLoS One. 2018; 13: e0202051. (IF=2.776, CI=3) 64. Okura Y, Ishigaki S, Sakakibara S, Yumoto C, Hashitate M, Sekine C, Fujita T, Takayama T, Ozaki K, Sato N, Minamino T. Prognosis of cancer patients with aortic stenosis under optimal cancer therapies and conservative cardiac treatments. Int Heart J. 2018; 59: 750-758. (IF=2.226, CI=5) 65. Kayamori H, Shimizu I, Yoshida Y, Hayashi Y, Suda M, Ikegami R, Katsuumi G, Wakasugi T, Minamino T. Amlodipine inhibits vascular cell senescence and protects against atherogenesis through the mechanism independent of calcium channel blockade. Int Heart J. 2018; 59: 607-613. (IF=2.226, CI=1) 66. Katsuumi G, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Wakasugi T, Nakao M, Minamino T. Catecholamine-induced senescence of endothelial cells and bone marrow cells promotes cardiac dysfunction in mice. Int Heart J. 2018; 59: 837-844. (IF=2.226, CI=4) 67. Ozawa T, Suda M, Ikegami R, Takano T, Wakasugi T, Yanagawa T, Tanaka K, Ozaki K, Hirono S, Minamino T. Dual antiplatelet therapy guided by CYP2C19 polymorphisms after implantation of second-generation drug-eluting stents for management of acute coronary syndrome. Int Heart J. 2018; 59: 21-26. (IF=2.226, CI=4) 68. Suda M, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Katsuumi G, Wakasugi T, Yoshida Y, Okuda S, Soga T, Minamino T. Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway. PLoS One. 2017; 12: e0182422. (IF=2.776, CI=6) 69. Kinoshita D, Nagasawa A, Shimizu I, Ito T, Yohko Y, Tsuchida M, Iwama A, Hayano T and Minamino T. Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway. Oncotarget 2017; 8: 34045-34056. (CI=5.618, CI=11) 70. Nishiuchi S, Makiyama T, Aiba T, Nakajima K, Hirose S, Kohjitani H, Yamamoto Y, Harita T, Hayano M, Wuriyanghai Y, Chen J, Sasaki K, Yagihara N, Ishikawa T, Onoue K, Murakoshi N, Watanabe I, Ohkubo K, Watanabe H, Ohno S, Doi T, Shizuta S, Minamino T, Saito Y, Oginosawa Y, Nogami A, Aonuma K, Kusano K, Makita N, Shimizu W, Horie M, Kimura T. Gene-based risk stratification for cardiac disorders in LMNA mutation carriers. Circ Cardiovasc Genet. 2017; 10. pii: e001603. doi:10.1161/CIRCGENETICS.116.001603. (IF=4.897, CI=16) 71. Aoyama N, Nishinari M, Ohtani S, Kanai A, Noda C, Hirata M, Miyamoto A, Watanabe M, Minamino T, Izumi T, Ako J. Clinical features and predictors of patients with critical limb ischemia who responded to autologous mononuclear cell transplantation for therapeutic angiogenesis. Heart Vessels. 2017; 32: 1099-1108. (IF=1.620, CI=5) 72. Sonoda K, Ohno S, Otuki S, Kato K, Yagihara N, Watanabe H, Makiyama T, Minamino T, Horie M. Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion. Europace. 2017; 19: 644-650. (IF=5.231, CI=7) 73. Otuki S, Hasegawa K, Watanabe H, Katsuumi G, Yagihara N, Iijima K, Sato A, Izumi D, Furushima H, Chinushi M, Aizawa Y, Minamino T. The effects of pure potassium channel blocker nifekalant and sodium channel blocker mexiletine on malignant ventricular tachyarrhythmias. J Electrocardiol. 2017; 50: 277-281. (IF=1.166, CI=4) 74. Yagihara N, Watanabe H, Barnett P, Duboscq-Bidot L, Thomas AC, Yang P, Ohno S, Hasegawa K, Kuwano R, Chatel S, Redon R, Schott JJ, Probst V, Koopmann TT, Bezzina CR, Wilde AA, Nakano Y, Aiba T, Miyamoto Y, Kamakura S, Darbar D, Donahue BS, Shigemizu D, Tanaka T, Tsunoda T, Suda M, Sato A, Minamino T, Endo N, Shimizu W, Horie M, Roden DM, Makita N. Variants in the SCN5A promoter associated with various arrhythmia phenotypes. J Am Heart Assoc. 2016; 5. doi: 10.1161/JAHA.116.003644. (IF=4.660, CI=7) 75. Hasegawa K, Watanabe H, Hisamatsu T, Ohno S, Itoh H, Ashihara T, Hayashi H, Makiyama T, Minamino T, Horie M. Early repolarization and risk of arrhythmia events in long QT syndrome. Int J Cardiol. 2016; 223: 540-542. (IF=3.471, CI=5) 76. Ozaki K, Okubo T, Tanaka K, Hosaka Y, Tsuchida K, Takahashi K, Oda H, Minamino T. Manifestation of latent left ventricular outflow tract obstruction in the acute phase of Takotsubo cardiomyopathy. Intern Med. 2016; 55: 3413-3420. (IF=0.956, CI=2) 77. Tahara N, Dobashi H, Fukuda K, Funauchi M, Hatano M, Ikeda S, Joho S, Kihara Y, Kimura T, Kondo T, Matsushita M, Minamino T, Nakanishi N, Ozaki Y, Saji T, Sakai S, Tanabe N, Watanabe H, Yamada H, Yoshioka K, Sasayama S. Efficacy and safety of a novel endothelin receptor antagonist, macitentan, in Japanese patients with pulmonary arterial hypertension. Circ J. 2016; 80: 1478-1483. (IF=3.025, CI=5) 78. Watanabe T, Kashimura T, Kodama M, Tanaka K, Fujiki S, Hayashi Y, Obata H, Hanawa H, Minamino T. Failing left ventricles have an enhanced post-stimulation potentiation despite their impaired force frequency relationship. Int Heart J. 2016; 57: 317-322. (IF=2.226, CI=0) 79. Sonoda K, Watanabe H, Hisamatsu T, Ashihara T, Ohno S, Hayashi H, Horie M, Minamino T. High Frequency of early repolarization and Brugada-type electrocardiograms in hypercalcemia. Ann Noninvasive Electrocardiol. 2016; 21: 30-40. (IF=1.235, CI=3) 80. Higashi Y, Azuma N, Takeishi Y, Minamino T, Kihara Y, Node K, Sata M, Fukumoto Y, Origasa H, Matsuo H, Naritomi H, Fujita M, Shimizu W. Effect of a low-Intensity pulsed ultrasound device, SX-1001, on clinical symptoms in Buerger disease with limb ischemia. Int Heart J. 2015; 56: 632-638. (IF=2.226, CI=1) 81. Hayashi Y, Hanawa H, Jiao S, Hasegawa G, Ohno Y, Yoshida K, Suzuki T, Kashimura T, Obata H, Tanaka K, Watanabe T, Minamino T. Elevated endomyocardial biopsy macrophage-related markers in intractable myocardial diseases. Inflammation 2015; 38: 2288-2299. (IF=2.939, CI=7) 82. Yoshida Y, Shimizu I, Katsuumi G, Jiao S, Suda M, Hayashi Y, Minamino T. p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload. J Mol Cell Cardiol. 2015; 85: 183-198. (IF=5.055, CI=24) 83. Iijima K, Chinushi M, Saitoh O, Hasegawa K, Sonoda K, Yagihara N, Sato A, Izumi D, Watanabe H, Furushima H, Aizawa Y, Minamino T. Frequency characteristics and associations with the defibrillation threshold of ventricular fibrillation in patients with implantable cardioverter defibrillators. Intern Med. 2015; 54: 1175-1182. (IF=0.956, CI=1) 84. Takayama T, Okura Y, Okada Y, Honma K, Nashimoto A, Sato N, Yokoyama A, Minamino T. Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients. Int J Clin Oncol. 2015; 20: 872-877. (IF=2.503, CI=6) 85. Ohno Y, Hanawa H, Jiao S, Hayashi Y, Yoshida K, Suzuki T, Kashimura T, Obata H, Tanaka K, Watanabe T, Minamino T. Liver congestion in heart failure contributes to inappropriately increased serum hepcidin despite anemia. Tohoku J Exp Med. 2015; 235: 69-79. (IF=1.584, CI=4) 86. Nagao S, Watanabe H, Sobue Y, Kodama M, Tanaka J, Tanabe N, Suzuki E, Narita I, Watanabe E, Aizawa Y, Minamino T. Electrocardiographic abnormalities and risk of developing cardiac events in extracardiac sarcoidosis. Int J Cardiol. 2015; 189: 1-5. (IF=3.471, CI=12) 87. Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I. Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling. Nat Commun. 2015; 6: 6241. (IF=11.878, CI=23) 88. Suzuki H, Kayama Y, Sakamoto M, Iuchi H, Shimizu I, Yoshino T, Katoh D, Nagoshi T, Tojo K, Minamino T, Yoshimura M, Utsunomiya K. Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of Diabetic Cardiomyopathy. Diabetes 2015; 64: 618-630. (IF=7.199, CI=56) 89. Nakagomi A, Okada S, Yokoyama M, Yoshida Y, Shimizu I, Miki T, Kobayashi Y, Minamino T. Role of the central nervous system and adipose tissue BDNF/TrkB axes in metabolic regulation. NPJ Aging Mech Dis. 2015; 1: 15009. (CI=9) 90. Ito TK, Yokoyama M, Yoshida Y, Nojima A, Kassai H, Oishi K, Okada S, Kinoshita D, Kobayashi Y, Fruttiger M, Aiba A, Minamino T. A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis. PLoS One 2014; 9: e102186. (IF=2.776, CI=16) 91. Kitada K, Nakano D, Ohsaki H, Hitomi H, Minamino T, Yatabe J, Felder RA, Mori H, Masaki T, Kobori H, Nishiyama A. Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy. J Diabetes Complications 2014; 28: 604-611. (IF=2.684, CI=44) 92. Yoshida Y, Hayashi Y, Suda M, Tateno K, Okada S, Moriya J, Yokoyama M, Nojima A,Yamashita M, Kobayashi Y, Shimizu I, Minamino T. Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway. PLoS One 2014; 9: e100359. (IF=2.776, CI=16) 93. Hamada N, Fujimichi Y, Iwasaki T, Fujii N, Furuhashi M, Kubo E, Minamino T, Nomura T, Sato H. Emerging issues in radiogenic cataracts and cardiovascular disease. J Radiat Res. 2014; 55: 831-846. (IF=2.014, CI=40) 94. Yokoyama M, Nakagomi A, Moriya J, Shimizu I, Nojima A, Yoshida Y, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Fruttiger M, Lozano G, Minamino T. Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity. Cell Rep. 2014; 7: 1691-1703. (IF=7.815, CI=37) 95. Maida Y, Yasukawa M, Okamoto N, Ohka S, Kinoshita K, Totoki Y, Ito TK, Minamino T, Nakamura H, Yamaguchi S, Shibata T, Masutomi K. Involvement of TERT in heterochromatin maintenance. Mol Cell Biol. 2014; 34: 1576-1593. (IF=3.735, CI=21) 96. Katsuumi G, Shimizu W, Watanabe H, Noda T, Nogami A, Ohkubo K, Makiyama T, Takehara N, Kawamura Y, Hosaka Y, Sato M, Fukae S, Chinushi M, Oda H, Okabe M, Kimura A, Maemura K, Watanabe I, Kamakura S, Horie M, Aizawa Y, Makita N, Minamino T. Efficacy of bepridil to prevent ventricular fibrillation in severe form of early repolarization syndrome. Int J Cardiol. 2014; 172: 519-522. (IF=3.471, CI=4) 97. Suzuki T, Hanawa H, Jiao S, Ohno Y, Hayashi Y, Yoshida K, Kashimura T, Obata H, Minamino T. Inappropriate expression of hepcidin by liver congestion contributes to anemia and relative iron deficiency. J Card Fail. 2014; 20: 268-277. (IF=3.967, CI=14) 98. Kashimura T, Kodama M, Watanabe T, Tanaka K, Hayashi Y, Ohno Y, Obata H, Ito M, Hirono S, Hanawa H, Minamino T. Relative refractoriness of left ventricular contraction underlies human tachycardia-induced mechanical and electrical alternans. Pacing Clin Electrophysiol. 2014; 37: 197-206. (IF=1.340, CI=3) 99. Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, Minamino T, Hirose K, Nakajima H. Tumor suppresser p53 inhibits systemic autoimmune diseases by inducing regulatory T cells. J Immunol. 2013; 191: 3614-3623. (IF=4.718, CI=34) 100. Ozasa Y, Akazawa H, Qin Y, Tateno K, Ito K, Kudo-Sakamoto Y, Yano M, Yabumoto C, Naito AT, Oka T, Lee JK, Minamino T, Nagai T, Kobayashi Y, Komuro I. Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cell. Hypertens Res. 2013; 36: 859-865. (IF=3.217, CI=26) 101. Shimizu I, Yoshida Y, Moriya J, Nojima A, Uemura A, Kobayashi Y, Minamino T. Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity. Cell Metab. 2013; 18: 491-504. (IF=22.415, CI=58) 102. Bezzina CR, Barc J, Mizusawa Y, Ann Remme C, Gourraud J-B, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Salling Olesen M, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden D, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott J-J, Dina C, Redon R. Common variants at the SCN5A/SCN10A and HEY2 loci predispose to Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet. 2013; 45: 1044-1049. (IF=25.455, CI=249) 103. Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Naoaki I, Minamino T. Haploinsufficiency of Akt1 prolongs the lifespan of mice. PLoS One 2013; 8: e69178. (IF=2.776, CI=33) 104. Sato A, Chinushi M, Izumi D, Furushima H, Minamino T. Malfunction of cardiac resynchronization therapy due to subsequent fracture of the ring and tip conductors of a co-radial left ventricular bipolar lead. Intern Med. 2013; 52: 1189-1193. (IF=0.956, CI=0) 105. Watanabe H, van der Werf C, Roses-Noguer F, Adler A, Sumitomo N, Veltmann C, Rosso R, Bhuiyan ZA, Bikker H, Kannankeril PJ, Horie M, Minamino T, Viskin S, Knollmann BC, Till J, Wilde AA. Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm 2013; 10: 542-547. (IF=5.225, CI=55) 106. Tomita K, Teratani T, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Nishiyama K, Mataki N, Irie R, Minamino T, Okada Y, Kurihara C, Ebinuma H, Saito H, Shimizu I, Yoshida Y, Hokari R, Sugiyama K, Hatsuse K, Yamamoto J, Kanai T, Miura S, Hibi Tp53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice. J Hepatol. 2012; 57: 837-843. (IF=18.946, CI=43) 107. Okada S, Yokoyama M, Toko H, Tateno K, Moriya J, Shimizu I, Nojima A, Ito T, Yoshida Y, Kobayashi Y, Katagiri H, Minamino T, Komuro I. Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol. 2012; 32: 1902-1909. (IF=6.618, CI=66) 108. Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I. Complement C1q activates canonical Wnt signaling and promotes age-related phenotypes. Cell 2012; 149: 1298-1313. (IF=36.216, CI=134) 109. Yasuda N, Akazawa H, Ito K, Shimizu I, Kudo-Sakamoto Y, Yabumoto C, Yano M, Yamamoto R, Ozasa Y, Minamino T, Naito AT, Oka T, Shiojima I, Tamura K, Umemura S, Nemer M, Komuro I. Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice. Hypertension 2012; 59: 627-633. (IF=7.017, CI=27) 110. Shimizu I, Yoshida Y, Katsuno T, Tateno K, Okada S, Moriya J, Yokoyama M, Nojima A, Ito T, Zechner R, Komuro I, Kobayashi Y, Minamino T. p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure. Cell Metab. 2012; 15: 51-64. (IF=22.415, CI=94) 111. Nakano D, Lei B, Kitada K, Hitomi H, Kobori H, Mori H, Deguchi K, Masaki T, Minamino T, Nishiyama A. Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. Am J Hypertens. 2012; 25: 354-358. (IF=2.530, CI=3) 112. Odaka K, Aoki I, Moriya J, Tateno K, Tadokoro H, Kershaw J, Minamino T, Irie T, Fukumura T, Komuro I, and Saga T. In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging. PLoS One 2011; 6: e25487. (IF=2.776, CI=5) 113. Wu X, Zou Y, Zhou Q, Huang L, Gong H, Sun A, Tateno K, Katsube K, Radtke F, Ge J, Minamino T, Komuro I. Role of JAGGED1 in arterial lesions after vascular injury. Arterioscler Thromb Vasc Biol. 2011; 31: 2000-2006. (IF=6.618, CI=23) 114. Toko H, Takahashi H, Kayama Y, Oka T, Minamino T, Okada S, Morimoto S, Zhan DY, Terasaki F, Anderson ME, Inoue M, Yao A, Nagai R, Kitaura Y, Sasaguri T, Komuro I. Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy. Circulation 2010; 122: 891-899. (IF=23.054, CI=64) 115. Toko H, Takahashi H, Kayama Y, Okada S, Minamino T, Terasaki F, Kitaura Y, and Komuro I. ATF6 is important under both pathological and physiological states in the heart. J Mol Cell Cardiol. 2010; 49:113-20. (IF=5.055, CI=48) 116. Naito AT, Okada S, Minamino T, Iwanaga K, Liu M, Sumida T, Nomura S, Sahara N, Mizoroki T, Takashima A, Akazawa H, Nagai T, Shiojima I, Komuro I. Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury. Circ Res. 2010; 106 :1692-1702. (IF=15.862, CI=85) 117. Shimizu I, Minamino T, Toko H, Okada S, Ikeda H, Yasuda N, Tateno K, Moriya J, Yokoyama M, Nojima A, Koh GY, Akazawa H, Shiojima I, Kahn CR, Abel ED and Komuro I. Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload. J Clin Invest. 2010; 120 :1506-1514. (Co-first author) (IF=12.282, CI=109) 118. Moriya J, Minamino T, Tateno K, Okada S, Uemura A, Shimizu I, Yokoyama M, Nojima A, Okada M, Koga H, Komuro I. Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis. Circ Res. 2010; 106: 391-398. (Co-first author) (IF=15.862, CI=44) 119. Minamino T, Orimo M, Shimizu I, Kunieda T, Yokoyama M, Ito T, Nojima A, Nabetani A, Oike Y, Matsubara H, Ishikawa F, Komuro I. A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med. 2009; 15: 1082-1087. (IF=30.641, CI=393) 120. Kayama Y, Minamino T*, Toko H, Sakamoto M, Shimizu I, Takahashi H, Okada S, Tateno K, Moriya J, Yokoyama M, Nojima A, Yoshimura M, Egashira K, Aburatani H and Komuro I. Cardiac 12/15-lipoxygenase-induced inflammation is involved in heart failure. J Exp Med. 2009; 206: 1565-1574. (Co-first author) (IF=10.892, CI=71) 121. Moriya J, Minamino T, Tateno K, Shimizu N, Kuwabara Y, Sato Y, Saito Y and Komuro I. Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia. Circ Cardiovasc Intervent. 2009; 2: 245-254. (Co-first author) (IF=6.088, CI=62) 122. Orimo M, Minamino T, Miyauchi H, Tateno K, Okada S, Moriya J, Komuro I. Protective role of SIRT1 in diabetic vascular dysfunction. Arterioscler Thromb Vasc Biol. 2009; 29: 889-894. (Co-first author) (IF=6.618, CI=142) 123. Nishi J, Minamino T, Miyauchi H, Nojima A, Tateno K, Okada S, Orimo M, Moriya J, Fong GH, Sunagawa K, Shibuya M, Komuro I. Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt. Circ Res 2008; 103: 261-268. (*Co-first author) (IF=15.862, CI=40) 124. Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M and Komuro I. IGFBP-4 is an inhibitor of canonical Wnt signaling required for cardiogenesis. Nature 2008; 454:345-349. (IF= 43.070, CI=158) 125. Kunieda T, Minamino T*, Miura K, Katsuno T, Tateno K, Miyauchi H, Kaneko S, Bradfield CA, FitzGerald GA, Komuro I. Reduced nitric oxide causes age-associated impairment of circadian rhythmicity. Circ Res. 2008; 102: 607-614. (Co-first author) (IF=15.862, CI=72) 126. Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin J D, Zou Y and Komuro I. p53-induced Inhibition of hif-1 causes cardiac dysfunction during pressure overload. Nature 2007; 446: 444-448. (Co-first author) (IF=43.070, CI=587) 127. Sakamoto M, Minamino T, Toko H, Kayama Y, Zou Y, Sano M, Takaki E, Aoyagi T, Tojo K, Tajima N, Nakai A, Aburatani H, Komuro I. Upregulation of Heat Shock Transcription Factor 1 Plays a Critical Role in Adaptive Cardiac Hypertrophy. Circ Res. 2006; 99: 1411-1418. (IF=15.862, CI=70) 128. Kunieda T, Minamino T*, Nishi J, Tateno K, Oyama T, Katsuno T, Miyauchi H, Orimo M, Okada S, Takamura M, Nagai T, Kaneko S and Komuro I. Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway. Circulation 2006; 114: 953-960. (Co-first author) (IF=23.054, CI=174) 129. Tateno K, Minamino T, Toko H, Akazawa H, Shimizu N, Takeda S, Kunieda T, Miyauchi H, Oyama T, Matsuura K, Nishi JI, Kobayashi Y, Nagai T, Kuwabara Y, Iwakura Y, Nomura F, Saito Y, Komuro I. Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization. Circ Res. 2006; 98: 1194-1202. (Co-first author) (IF=15.862, CI=139) 130. Kunieda T, Minamino T, Katsuno T, Tateno K, Nishi JI, Miyauchi H, Orimo M, Okada S, Komuro I. Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res. 2006; 98: 532-539. (IF=15.862, CI=72) 131. Naito AT, Akazawa H, Takano H, Minamino T, Nagai T, Aburatani H, Komuro I. Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling. Circ Res. 2005; 22: 144-151. (IF=15.862, CI=90) 132. Harada M, Qin Y, Takano H, Minamino T, Zou Y, Toko H, Ohtsuka M, Matsuura K, Sano M, Nishi J, Iwanaga K, Akazawa H, Kunieda T, Zhu W, Hasegawa H, Kunisada K, Nagai T, Nakaya H, Yamauchi-Takihara K, Komuro I. G-CSF prevents cardiac remodeling after myocardial infarction by activating Jak/Stat in cardiomyocytes. Nat Med. 2005; 11: 305-311. (*Co-first author) (IF=30.641, CI=475) 133. Matsuura K, Wada H, Nagai T, Iijima Y, Minamino T, Sano M, Akazawa H, Molkentin JD, Kasanuki H, Komuro I. Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle. J Cell Biol. 2004; 167: 351-363. (IF=8.891, CI=100) 134. Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T, Makita N, Iwanaga K, Zhu W, Kudoh S, Toko H, Tamura K, Kihara M, Nagai T, Fukamizu A, Umemura S, Iiri T, Fujita T, Komuro I. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol. 2004; 6: 499-506. (IF=17.728, CI=453) 135. Toko H, Zou Y, Minamino T, Sakamoto M, Sano M, Harada M, Nagai T, Sugaya T, Terasaki F, Kitaura Y, Komuro I. Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium. Arterioscler Thromb Vasc Biol. 2004; 24: 664-670. (IF=6.618, CI=35) 136. Miyauchi H, Minamino T, Tateno K, Kunieda T, Toko H, Komuro I. Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway. EMBO J. 2004; 23 212–220. (Co-first author) (IF=11.227, CI=235) 137. Zou Y, Zhu W, Sakamoto M, Qin Y, Akazawa H, Toko H, Mizukami M, Takeda N, Minamino T, Takano H, Nagai T, Nakai A, Komuro I. Heat shock transcription factor 1 protects cardiomyocytes from ischemia/reperfusion injury. Circulation 2003; 108: 3024-3030. (IF=23.054, CI=60) 138. Minamino T, Yoshida T, Tateno K, Miyauchi H, Zou Y, Toko H, Komuro I. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 2003; 108: 2264-2269. (IF=23.054, CI=145) 139. Zou Y, Takano H, Mizukami M, Akazawa H, Qin Y, Toko H, Sakamoto M, Minamino T, Nagai T, Komuro I. Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration of myocardium after myocardial infarction. Circulation 2003; 108: 748-753. (IF=23.054, CI=76) 140. Zampetaki A, Minamino T, Mitsialis SA, Kourembanas S. Effect of heme oxygenase-1 overexpression in two models of lung inflammation. Exp Biol Med. 2003; 228: 442-446. (IF=3.005, CI=53) 141. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis. J Cardiol. 2003; 41: 39-40. (IF=2.289, CI=19) 142. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis. Role of telomere in endothelial dysfunction. Circulation. 2002; 105: 1541-1544. (IF=23.054, CI=627) 143. Minamino T, Toko H, Tateno K, Nagai T, Komuro I. Peripheral-blood or bone-marrow mononuclear cells for therapeutic angiogenesis? Lancet 2002; 360:2083-2084. (IF=59.102, CI=62) 144. Minamino T, Christou H, Hsieh C-M, Liu Y, Dhawan V, Abraham NG, Perrella MA, Mitsialis SA and Kourembanas S. Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci USA. 2001; 98:8798-8803. (IF=9.580, CI=303) 145. Minamino T and Kourembanas S. Mechanisms of telomerase induction during vascular smooth muscle cell proliferation. Circ Res. 2001; 89:237-243. (IF=15.862, CI=66) 146. Minamino T, Mitsialis SA and Kourembanas S. Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation. Mol Cell Biol 2001; 21:3336-3342. (IF=3.735, CI=137) 147. Morita H, Taguchi J, Kurihara H, Kitaoka M, Kaneda H, Kurihara Y, Maemura K, Shindo T, Minamino T, Ohno M, Yamaoki K, Ogasawara K, Aizawa T, Suzuki S and Yazaki Y. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase as a risk factor for coronary artery disease. Circulation 1997; 95:2032-2036. (IF=23.054, CI=301) 148. Morita H, Kaneda H, Kurihara Y, Maemura K, Shindo T, Minamino T, Ohno M, Yamaoki K, Ogasawara K, Aizawa T, Suzuki S and Yazaki Y. Gene Polymorphism of 5,10-methylenetetrahydrofolate reductase as a coronary risk factor. J Cardiol. 1997; 29:309-315. (IF= 2.289, CI=18) 149. Minamino T, Kurihara H, Takahashi M, Shimada K, Maemura K, Oda H, Ishikawa T, Uchiyama T, Tanzawa K and Yazaki Y. Endothelin converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis. Circulation 1997; 95: 221-230. (IF=23.054, CI=108) 150. Iwata H, Minamino T. Identification of a novel therapeutic target in vascular dysfunction: A showcase of reverse and forward translational research linking between bench and bedside. Eur Heart J. 2021 (in press). 151. Ito M, Matsue Y, Minamino T. Worsening renal function during intensive blood pressure control: another example of not prognostically relevant creatinine rise? Eur J Heart Fail. 2021 Mar;23(3):393-395. 152. Shimizu I, Minamino T. Cellular Senescence in Arterial Diseases. J Lipid Atheroscler. 2020; 9(1): 79-91. 153. Shimizu I, Minamino T. Cellular senescence in cardiac diseases. J Cardiol. 2019; 74: 313-319. (IF=2.289, CI=4) 154. Ikegami R, Shimizu I, Yoshida Y, Minamino T. Metabolomic analysis in heart failure. Circ J. 2018; 82: 10-16. (IF=3.025, CI=8) 155. Watanabe H, Minamino T. Atrial fibrillation in patients with end-stage kidney disease on dialysis. Intern Med. 2018; 57: 2285-2286. (IF=0.956, CI=1) 156. Katsuumi G, Shimizu I, Yoshida Y, Minamino T. Vascular senescence in cardiovascular and metabolic diseases. Front Cardiovasc Med. 2018; 5: 18. doi: 10.3389/fcvm.2018.00018. (CI=25) 157. Moriya J, Minamino T. Angiogenesis, cancer, and vascular aging. Front Cardiovasc Med. 2017; 4: 65. (CI=11) 158. Watanabe H, Minamino T. Rare variants in ANK2 associated with various inherited arrhythmia syndromes. Circ J. 2016; 80: 2423-2424. (IF=3.025, CI=0) 159. Shimizu I, Minamino T. Physiological and pathological cardiac hypertrophy. J Mol Cell Cardiol. 2016; 97: 245-262. (IF=5.055, CI=198) 160. Watanabe H, Minamino T. Genetics of Brugada syndrome. J Hum Genet. 2016; 61: 57-60. (IF=3.545, CI=31) 161. Shimizu I, Yoshida Y, Minamino T. A role for circadian clock in metabolic disease. Hypertens Res. 2016; 39: 483-491. (IF=3.217, CI=17) 162. Katsuumi G, Shimizu I, Yoshida Y, Minamino T. The pathological role of vascular aging in cardio-metabolic disorder. Inflamm Regen. 2016; 36: 16. 163. Shimizu I, Yoshida Y, Minamino T. Maintenance of subcutaneous fat homeostasis improves systemic metabolic dysfunction in obesity. Diabetes 2015; 64: 3984-3986. (IF=7.199, CI=8) 164. Shimizu I, Yoshida Y, Minamino T. Pathological role of adipose tissue dysfunction in cardio-metabolic disorders. Int Heart J. 2015; 56: 255-259. (IF=2.226, CI=7) 165. Yoshida Y, Shimizu I, Minamino T. The pathological role of adipose tissue aging in the progression of systemic insulin resistance. Inflammation and regeneration 2015; 35: 178-184. 166. Shimizu I, Yoshida Y, Suda M, Minamino T. DNA damage response and metabolic disease. Cell Metab. 2014; 20: 967-977. (IF=22.415, CI=84) 167. Shimizu I, Yoshida Y, Katsuno T, Minamino T. Adipose tissue inflammation in diabetes and heart failure. Microbes and Infection 2013; 15: 11-17. (IF=2.699, CI=13) 168. Watanabe H, Minamino T. Role of mutations in L-type calcium channel genes in Brugada syndrome, early repolarization syndrome, and idiopathic ventricular fibrillation associated with right bundle branch block. Circ J. 2013; 77: 1689-1690. (IF=3.025, CI=3) 169. Minamino T. Role of cellular senescence in lifestyle-related disease Circ J. 2010; 74: 2527-2533. (IF=3.025, CI=10) 170. Minamino T. Gap junctions mediate the spread of ischemia-reperfusion injury. Circ J. 2009; 73, 1591-1592. (IF=3.025, CI=6) 171. Minamino T and Komuro I. Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes. Nat Rev Cardiol (Nat Clin Pract Cardiovasc Med). 2008; 5: 637-648. (IF= 17.420, CI=74) 172. Toko H, Minamino T, Komuro I. Role of heat shock transcriptional factor 1 and heat shock proteins in cardiac hypertrophy. Trends Cardiovasc Med. 2008; 18: 88-93. (IF=4.462 CI=20) 173. Minamino T and Komuro I. Role of telomeres in vascular senescence. Front Biosci. 2008; 13: 2971-2979. (IF=3.736, CI=30) 174. Tateno K, Minamino T, Moriya J, Katada A, Yokoyama M, Miura K, Komuro I. Cell therapy for cardiovascular diseases. Ann Vasc Dis 2008; 1: 66-79. 175. Minamino T and Komuro I. Vascular cell senescence: Contribution to atherosclerosis. Circ Res. 2007; 100: 15-26. (IF=15.862, CI=374) 176. Minamino T and Komuro I. Critical roles of insulin-induced senescence in diabetic vasculopathy. Vascular Disease Prevention 2007; 4: 194-200. (CI=0) 177. Minamino T, Komuro I. Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury. J Clin Invest. 2006; 116: 2316-2319. (IF=12.282, CI=76) 178. Tateno K, Minamino T, Miyauchi H, Kunieda T, Komuro I. Application of hematopoietic cells to therapeutic angiogenesis. Curr Pharm Des. 2006; 12: 557-563. (IF=2.412, CI=8) 179. Minamino T, Miyauchi H, Yoshida T, Tateno K and Komuro I. The role of vascular cell senescence in atherosclerosis. Antisenescence as a novel therapeutic strategy for vascular aging. Curr Vasc Pharmacol. 2004; 2: 141-148. (IF=2.583, CI=39) 180. Minamino T, Miyauchi H, Tateno K, Kunieda T, Komuro I. Akt-induced senescence: Impication for human disease. Cell Cycle 2004; 4: 449-451. (IF=3.259, CI=0) 181. Minamino T, Miyauchi H, Yoshida T, Tateno K, Kunieda T, Komuro I. Vascular cell senescence and vascular aging. J Mol Cell Cardiol. 2004; 36:175-183. (IF=5.055, CI=114) 182. Minamino T and Komuro I. The role of telomerase activation in the regulation of vascular smooth muscle cell proliferation. Drug News Perspect. 2003; 16:211-216. (IF=3.132, CI=9) 183. Minamino T and Komuro I. Role of telomere in endothelial dysfunction in atherosclerosis. Curr Opin Lipidol. 2002; 13:537-543. (IF=4.844, CI=40) Case reports: 184. Otsuki S, Izumi D, Hasegawa Y, Yagihara N, Iijima K, Minamino T. Suppression of cardiac memory-related severe form of torsades de pointes by landiolol in a patient with congenital long QT syndrome type 2. Heart Rhythm Case Rep. 2020; 6(7): 407-410. 185. Kubota H, Endo H, Ishii H, Tsuchiya H, Inaba Y, Terakawa K, Takahashi Y, Noma M, Takemoto K, Taniai S, Sakata K, Soejima K, Shimoyamada H, Kamma H, Kawakami H, Kaneko Y, Hirono S, Izumi D, Ozaki K, Minamino T, Yoshino H, Sudo K. Adult ALCAPA: from histological picture to clinical features. J Cardiothorac Surg 2020; 15: 14. (IF=1.470, CI=0) 186. Takano T, Ozaki K, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Angioscopic findings during balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension. Cardiovasc Interv Ther 2020; 35(4): 421-422.. 187. Sato A, Yagihara N, Hasegawa Y, Otuki S, Iijima K, Izumi D, Minamino T. A steam pop detected by intracardiac echocardiography during catheter ablation of the left ventricular papillary muscle. Int Heart J. 2019; 60: 199-203. (IF=2.226, CI=0) 188. Hoyano M, Ozaki K, Nishida K, Sakai R, Kubota N, Takano T, Okubo T, Kimura S, Yanagawa T, Ozawa T, Kashimura T, Minamino T. High-resolution angioscopy of endoluminal stent graft at 6 months after implantation. Circ J. 2019; 83: 1970. (IF=3.025, CI=0) 189. Sato A, Hasegawa Y, Haniu H, Shiraishi S, Yagihara N, Iijima K, Izumi D, Minamino T. Replacement of an implantable cardioverter-defibrillator (ICD) with a newstandard subcutaneous ICD system in a patient with Jervell and Lange-Nielsen syndrome. Int Heart J. 2019; 60: 1206-1210. (IF=2.226, CI=0) 190. Takano T, Ozaki K, Hoyano M, Yanagawa T, Ozawa T, Minamino T. Stent malapposition occurred 17 days following percutaneous coronary intervention for a severe calcified lesion in acute myocardial infarction. J Cardiol Cases. 2019; 20: 4-7. (CI=0) 191. Sato A,* Takano T, Chinushi M, Minamino T. Usefulness of the intravenous flecainide challenge test before oral flecainide treatment in a patient with Andersen-Tawil syndrome. BMJ Case Rep. 2019; 12. pii: e229628. (CI=1) 192. Kayamori H, Kashimura T, Horii Y, Kanazawa T, Fujita T, Kubota N, Ikami Y, Takano T, Okubo T, Hoyano M, Yanagawa T, Ozawa T, Ozaki K, Minamino T. Bidirectional shunt trajectory in ventricular septal defect with Eisenmenger's syndrome. Circ J. 2018; 82: 2925-2926. (IF=3.025, CI=0) 193. Takano T, Ozaki K, Tanaka K, Yanagawa T, Ozawa T, Minamino T. Efficacy of corticosteroid treatment for refractory multivessel vasospastic coronary angina with hypereosinophilia. Intern Med. 2018; 57: 3111-3115. (IF=0.956, CI=1) 194. Sakaguchi Y, Ozaki K, Takano T, Namba H, Tanaka K, Yanagawa T, Ozawa T, Minamino T. Dynamic left ventricular outflow tract obstruction complicated with takotsubo cardiomyopathy: The acute phase of takotsubo cardiomyopathy manifests latent left ventricular outflow tract obstruction. J Cardiol Cases. 2018; 18: 60-64. (CI=0) 195. Ikegami R, Ozaki K, Ozawa T, Hirono S, Ito M, Minamino T. Percutaneous Coronary intervention for a patient with left main coronary compression syndrome. Intern Med. 2018; 57: 1421-1424. (IF=0.956, CI=1) 196. Takayama T, Ozawa T, Sanada A, Watanabe T, Ito M, Hirono S, Aizawa Y, Minamino T. Aortic regurgitation presenting with recurrent detachment of a prosthetic valve, as the first presenting symptom of cardiovascular Behçet's disease. Intern Med. 2018; 57: 823-827. (IF=0.956, CI=0) 197. Iijima K, Ishida N, Izumi D, Minamino T. Inappropriate inhibition of biventricular pacing due to diaphragmatic myopotentials amplified by the selectable sensing filter. Europace. 2017; 19: 2014. (IF=5.231, CI=0) 198. Sato A, Hasegawa Y, Minamino T. The first reported case of a transvenous left ventricular pacing lead of cardiac resynchronization therapy causing aggravation of coronary atherosclerosis. Europace. 2016; 18: 1734. (IF=5.231, CI=0) 199. Tagawa M, Nanba H, Suzuki H, Nakamura Y, Uchiyama H, Ochiai S, Terunuma M, Yahata K, Minamino T. Ventricular rhythm and hypotension in a patient with pheochromocytoma-induced myocardial damage and reverse Takotsubo cardiomyopathy. Intern Med. 2015; 54: 2343-2349. (IF=0.956, CI=4) 200. Watanabe T, Kashimura T, Obata H, Minamino T. Cibenzoline abolished pulsus alternans in a HOCM patient. Intern Med. 2015; 54: 2273. (IF=0.956, CI=0) 201. Suzuki H, Hoshina S, Ozawa J, Sato A, Minamino T, Aizawa Y, Saitoh A. Short QT syndrome in a boy diagnosed on screening for heart disease. Pediatr Int 2014; 56: 774-776. (IF=0.939, CI=7) 202. Sato A, Watanabe H, Sonoda K, Chinushi M, Tsuda T, Izumi D, Furushima H, Minamino T. Augmentation of the J wave by rapid pacing in a patient with vasospastic angina. Int J Cardiol. 2014; 172: e111-113. (IF=3.471, CI=3) 203. Watanabe H, Ohkubo K, Watanabe I, Matsuyama TA, Ishibashi-Ueda H, Yagihara N, Shimizu W, Horie M, Minamino T, Makita N. SCN5A mutation associated with ventricular fibrillation, early repolarization, and concealed myocardial abnormalities. Int J Cardiol. 2013; 165: e21-23. (IF=3.471, CI=11) 204. Watanabe T, Hanawa H, Suzuki T, Jiao S, Yoshida K, Ogura M, Ohno Y, Hayashi Y, Ito M, Kashimura T, Obata H, Sato A, Ozawa T, Kodama M, Sakuraba H, Minamino T. A mutant mRNA expression in an endomyocardial biopsy sample obtained from a patient with a cardiac variant of Fabry disease caused by a novel acceptor splice site mutation in the invariant AG of intron 5 of the α-galactosidase A gene. Intern Med. 2013; 52: 777-780. (IF=0.956, CI=5) 205. Narumi H, Funabashi N, Takano H, Sekine T, Ueda M, Hori Y, Fukawa T, Minamino T, Kobayashi Y, Komuro I. Remarkable thickening of right atrial wall in subjects with cardiac amyloidosis complicated with sick sinus syndrome. Int J Cardiol. 2007; 119: 222-224. (IF=3.471, CI=12) 206. Uehara M, Funabashi N, Ogawa Y, Minamino T, Komuro I. Double outlet right ventricle demonstrated by multislice computed tomography. Int J Cardiol. 2007; 121: 218-220. (IF=3.471, CI=13) 207. Naito AT, Minamino T, Tateno K, Nagai T, Komuro I. Steroid-responsive thromboangiitis obliterans. Lancet 2004; 364: 1098. (IF=59.102, CI=8) Books: 208. Katsuumi G, Minamino T. Cellular Senescence in Disease. 7. Vascular diseases. ii. Atherosclerosis. 2020 (in press) (Elsevier Textbook). 209. Suda M, Shimizu I, Yoshida Y, Katsuumi G, Minamino T. Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease. Endothelial cell dysfunction and Senescence: Biologic mechanisms and Hemodynamic consequences. 2020 (in press) (Elsevier Textbook). 210. Suda M, Shimizu I, Yoshida Y, Minamino T. Chapter 2. Peripheral Blood Mononuclear Cells for Limb Ischemia. 2017: 25–43. (Springer publication). 211. Yoshida Y, Shimizu I, Minamino T. Diabetes and adipocyte dysfunction. Diabetes and Aging-related Complications. 2017: 69-84. (Springer publication). 212. Minamino T, Komuro I. Vascular cell senescence in human atherosclerosis. In: Atherosclerosis XIII (edited by Yuji Matsuzawa, Toru Kita, Ryozo Nagai, and Tamio Teramoto), p566-569, ELSEVIER, Netherlands, 2004.

研究テーマ

循環器内科学

研究業績（論文）

1. Suda M, Shimizu I, Katsuumi G, Yoshida Y, Matsumoto N, Hayashi Y, Ikegami R, Yoshida Y, Mikawa R, Katayama A, Wada J, Seki M, Suzuki Y, Iwama A, Nakagami H, Nagasawa A, Morishita R, Sugimoto M, Okuda S, Tsuchida M, Ozaki K, Nakanishi-Matsui M, Minamino T. Senolytic vaccination improves pathological aging. Nat Aging. 2021 (in press).
2. Fukase T, Dohi T, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. Serum apolipoprotein E levels predict residual cardiovascular risk in patients with chronic coronary syndrome undergoing first percutaneous coronary intervention and on-statin treatment. Atherosclerosis. 2021 Aug 12;333:9-15.
3. Morisawa T, Saitoh M, Takahashi T, Watanabe H, Mochizuki M, Kitahara E, Fujiwara T, Fujiwara K, Nishitani-Yokoyama M, Minamino T, Shimada K, Honzawa A, Shimada A, Yamamoto T, Asai T, Amano A, Daida H. Association of phase angle with hospital-acquired functional decline in older patients undergoing cardiovascular surgery. Nutrition. 2021 Jun 26;91-92:111402.
4. Noguchi M, Dohi T, Okazaki S, Matsumura M, Takeuchi M, Endo H, Kato Y, Okai I, Nishiyama H, Doi S, Iwata H, Isoda K, Usui E, Fujimura T, Seike F, Mintz GS, Miyauchi K, Daida H, Minamino T, Maehara A. Comparison of 6-month vascular healing response after bioresorbable polymer versus durable polymer drug-eluting stent implantation in patients with acute coronary syndromes: A randomized serial optical coherence tomography study. Catheter Cardiovasc Interv. 2021 (in press)
5. Kaneko T, Kagiyama N, Nakamura Y, Hirasawa T, Murata A, Morimoto R, Miyazaki S, Minamino T. Effectiveness of real-time tele-ultrasound for echocardiography in resource-limited medical teams. J Echocardiogr. 2021 (in press)
6. Otsuki S, Izumi D, Sakaguchi Y, Suzuki N, Hakamata T, Ikami Y, Hasegawa Y, Yagihara N, Iijima K, Chinushi M, Minamino T, Takayuki I. Efficacy of antitachycardia pacing alert by remote monitoring of implantable cardioverter-defibrillators for out-of-hospital electrical storm. Pacing Clin Electrophysiol. 2021 (in press)
7. Shiozaki M, Sumiyoshi M, Tabuchi H, Hayashi H, Tamura H, Inoue K, Minamino T. A Case of J Wave Syndrome Due to Severe Hypercalcemia with Ventricular Fibrillation Storm and Successful Treatment of Isoproterenol Infusion. Int Heart J. 2021;62(4):924-926.
8. Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. High Apolipoprotein E Levels Predict Adverse Limb Events in Patients with Peripheral Artery Disease Due to Peripheral Artery Disease Undergoing Endovascular Treatment and On-Statin Treatment. Int Heart J. 2021 Jul 30;62(4):872-878.
9. Takeuchi M, Dohi T, Fukase T, Nishio R, Takahashi N, Endo H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. Comparison of clinical outcomes between percutaneous coronary intervention for de novo lesions versus in-stent restenosis lesions. Cardiovasc Interv Ther. 2021 (in press)
10. Fujiki S, Watanabe H, Obata H, Suda M, Mitsuma W, Tomii A, Sakai K, Uehara A, Shimizu I, Kashimura T, Ozaki K, Minamino T. Association of adipokines with frailty in heart failure. Acta Biomed. 2021 Jul 1;92(3):e2021195.
11. Nozaki YO, Fujimoto S, Aoshima C, Kamo Y, Kawaguchi YO, Takamura K, Kudo A, Takahashi D, Hiki M, Kato Y, Okai I, Dohi T, Okazaki S, Tomizawa N, Kumamaru KK, Aoki S, Minamino T. Comparison of diagnostic performance in on-site based CT-derived fractional flow reserve measurements. Int J Cardiol Heart Vasc. 2021 (in press)
12. Ishiwata S, Matsue Y, Nakamura Y, Dotare T, Sunayama T, Suda S, Yatsu S, Kato T, Hiki M, Kasai T, Minamino T. Clinical and prognostic values of urinary alpha1-microglobulin as a tubular marker in acute heart failure. Int J Cardiol. 2021 (in press)
13. Matsuo Y, Ozaki K, Ikegami R, Nishida K, Kubota N, Takano T, Okubo T, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Conservative treatment with an intra-aortic balloon pump to treat acute myocardial infarction due to spontaneous coronary artery dissection. J Cardiol Cases. 2021 Jan 30;23(6):274-280.
14. Nishitani-Yokoyama M, Shimada K, Yamada M, Honzawa A, Kunimoto M, Sugita Y, Fujiwara K, Matsubara T, Matsumori R, Abulimiti A, Shimada A, Yamamoto T, Asai T, Amano A, Saitoh M, Morisawa T, Takahashi T, Daida H, Minamino T. Association Between Constipation and Frailty Components in Patients Undergoing Late Phase II Cardiac Rehabilitation. Cardiol Res. 2021 Jun;12(3):169-176.
15. Takeuchi M, Wada H, Ogita M, Takahashi D, Okada-Nozaki Y, Nishio R, Yasuda K, Takahashi N, Sonoda T, Yatsu S, Shitara J, Tsuboi S, Dohi T, Suwa S, Miyauchi K, Daida H, Minamino T. Impact of Prior Stroke on Long-Term Outcomes in Patients With Acute Coronary Syndrome. Circ Rep. 2021 Apr 9;3(5):267-272.
16. Kagiyama N, Hiki M, Matsue Y, Dohi T, Matsuzawa W, Daida H, Minamino T, Kasai T. Validation of telemedicine-based self-assessment of vital signs for patients with COVID-19: A pilot study. J Telemed Telecare. 2021 (in press)
17. Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. Long-term impact of high-sensitivity C-reactive protein in patients with intermittent claudication due to peripheral artery disease following endovascular treatment. Heart Vessels. 2021 (in press)
18. Kubota N, Ozaki K, Tanabe Y, Iwasaki Y, Yoshida T, Okubo T, Kimura S, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Usefulness of Repeat Angiography to Establish Spontaneous Coronary Artery Dissection in Small Vessels. Circ Rep. 2020 Oct 29;2(12):739-743.
19. Hasegawa Y, Izumi D, Ikami Y, Otsuki S, Yagihara N, Iijima K, Chinushi M, Minamino T. Progressive increase in activation delay during premature stimulation is related to ventricular fibrillation in Brugada syndrome. J Cardiovasc Electrophysiol. 2021 (in press)
20. Ozaki K, Okubo T, Hagiya K, Kubota N, Tsuchida K, Takahashi K, Oda H, Minamino T. Unstable angina complicated with dynamic left ventricular outflow tract obstruction. J Cardiol Cases. 2021 Feb 12;23(4):181-188.
21. Hagiya K, Ozaki K, Nanasato M, Iguchi N, Takayama M, Shimokawa T, Tanabe N, Minamino T, Isobe M. Relationship Between Heart Rate at Discharge and Long-Term Outcomes of Surgically Treated Patients With Type A Acute Aortic Dissections. Circ J. 2021 (in press)
22. Hsiao YT, Shimizu I, Wakasugi T, Yoshida Y, Ikegami R, Hayashi Y, Suda M, Katsuumi G, Nakao M, Ozawa T, Izumi D, Kashimura T, Ozaki K, Soga T, Minamino T. Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy. Sci Rep. 2021 Mar 24;11(1):6722.
23. Takahashi N, Dohi T, Endo H, Takeuchi M, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. Coronary lipid-rich plaque characteristics in Japanese patients with acute coronary syndrome and stable angina: A near infrared spectroscopy and intravascular ultrasound study. Int J Cardiol Heart Vasc. 2021 Mar 11;33:100747.
24. Fujiwara K, Shimada K, Nishitani-Yokoyama M, Kunimoto M, Matsubara T, Matsumori R, Abulimiti A, Aikawa T, Ouchi S, Shimizu M, Fukao K, Miyazaki T, Honzawa A, Yamada M, Saitoh M, Morisawa T, Takahashi T, Daida H, Minamino T. Arterial Stiffness Index and Exercise Tolerance in Patients Undergoing Cardiac Rehabilitation. Int Heart J. 2021 Mar 30;62(2):230-237.
25. Fukuda K, Okazaki S, Shiozaki M, Okai I, Nishino A, Tamura H, Inoue K, Sumiyoshi M, Daida H, Minamino T. Ultrasound-guided puncture reduces bleeding-associated complications, regardless of calcified plaque, after endovascular treatment of femoropopliteal lesions, especially using the antegrade procedure: A single-center study. PLoS One. 2021 Mar 12;16(3):e0248416.
26. Abulimiti A, Nishitani-Yokoyama M, Shimada K, Kunimoto M, Matsubara T, Fujiwara K, Aikawa T, Ouchi S, Sugita Y, Fukao K, Kadoguchi T, Miyazaki T, Shimada A, Yamamoto T, Takahashi T, Fujiwara T, Asai T, Amano A, Daida H, Minamino T. Prognostic impact of peak oxygen uptake and heart rate reserve in patients after off-pump coronary artery bypass grafting. Clin Cardiol. 2021 Apr;44(4):580-587.
27. Takeuchi M, Dohi T, Takahashi N, Endo H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. The prognostic implications of chronic kidney disease and anemia on long-term outcomes in patients undergoing percutaneous coronary intervention. Heart Vessels. 2021 (in press)
28. Matsuo Y, Yoshimine F, Fuse K, Suzuki K, Sakamoto T, Iijima K, Ozaki K, Minamino T. Regional Disparities in Adherence to Guidelines for the Treatment of Chronic Heart Failure. Intern Med. 2021;60(4):525-532.
29. Minami-Takano A, Iwata H, Miyosawa K, Shiozawa T, Hayashi H, Funamizu T, Ishii K, Nozaki Y, Tabuchi H, Sekita G, Shimada K, Sumiyoshi M, Nakazato Y, Daida H, Minamino T. The association between impairment of HDL cholesterol efflux capacity and atrial remodeling in atrial fibrillation. Sci Rep. 2021 Feb 11;11(1):3547.
30. Hirose S, Matsue Y, Kamiya K, Kagiyama N, Hiki M, Dotare T, Sunayama T, Konishi M, Saito H, Saito K, Ogasahara Y, Maekawa E, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Momomura SI, Minamino T. Prevalence and prognostic implications of malnutrition as defined by GLIM criteria in elderly patients with heart failure. Clin Nutr. 2021 (in press)
31. Hasegawa Y, Watanabe H, Ikami Y, Otsuki S, Iijima K, Yagihara N, Izumi D, Minamino T. J point elevation in high precordial leads associated with risk of ventricular fibrillation. Ann Noninvasive Electrocardiol. 2020; e12820.
32. Chikata Y, Iwata H, Doi S, Funamizu T, Okazaki S, Dohi S, Higuchi R, Saji M, Takamisawa I, Tamura H, Amano A, Daida H, Minamino T. Simultaneous Estimation of Gender Male and Atrial Fibrillation as Risk Factors for Adverse Outcomes Following Transcatheter Aortic Valve Implantation. J Clin Med. 2020; 9(12): 3963.
33. Kato Y, Dohi T, Chikata Y, Fukase T, Takeuchi M, Takahashi N, Endo H, Nishiyama H, Doi S, Okai I, Iwata H, Isoda K, Okazaki S, Miyauchi K, Daida H, Minamino T. Predictors of discordance between fractional flow reserve and resting full-cycle ratio in patients with coronary artery disease: Evidence from clinical practice. J Cardiol. 2021 Mar;77(3):313-319.
34. Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T. Long-term clinical outcomes and cause of death after endovascular treatment for femoropopliteal artery lesions. J Cardiol. 2021 Apr;77(4):417-423.
35. Honzawa A, Nishitani-Yokoyama M, Shimada K, Kunimoto M, Yamada M, Matsubara T, Matsumori R, Fujiwara K, Abulimiti A, Aikawa T, Ouchi S, Shimizu M, Sugita Y, Shimada A, Yamamoto T, Amano A, Asai T, Saito M, Morisawa T, Takahashi T, Fujiwara T, Daida H, Minamino T. Relationship Between Kihon Checklist Score and Anxiety Levels in Elderly Patients Undergoing Early Phase II Cardiac Rehabilitation. Cardiol Res. 2020; 11(6): 405-411.
36. Kubota N, Ozaki K, Hoyano M, Nishida K, Takano T, Okubo T, Kimura S, Yanagawa T, Kashimura T, Minamino T. Long-Term Prognosis of Patients Who Underwent Percutaneous Transvenous Mitral Commissurotomy for Mitral Stenosis. Int Heart J. 2020; 61(6): 1183-1187.
37. Sai E, Shimada K, Aikawa T, Aoshima C, Takamura K, Hiki M, Yokoyama T, Miyazaki T, Fujmoto S, Konishi H, Hirano KI, Daida H, Minamino T. Triglyceride Deposit Cardiomyovasculopathy with Massive Myocardial Triglyceride which was Proven Using Proton-magnetic Resonance Spectroscopy. Intern Med. 2021 Apr 15;60(8):1217-1220.
38. Kubota N, Ozaki K, Hakamata T, Ikami Y, Hoyano M, Minamino T. Angioscopic findings of organized thrombosis of iliac vein in patient with chronic thromboembolic pulmonary hypertension. Cardiovasc Interv Ther. 2020 (in press).
39. Kubota N, Ozaki K, Hoyano M, Minamino T. Angioscopic Findings of Deep Vein Thrombosis Treated by Balloon Angioplasty With Catheter-Directed Thrombolysis. Circ J. 2020; 84(12): 2320.
40. Miyosawa K, Iwata H, Minami-Takano A, Hayashi H, Tabuchi H, Sekita G, Kadoguchi T, Ishii K, Nozaki Y, Funamizu T, Chikata Y, Matsushita S, Amano A, Sumiyoshi M, Nakazato Y, Daida H, Minamino T. Enhanced monocyte migratory activity in the pathogenesis of structural remodeling in atrial fibrillation. PLoS One. 2020; 15(10): e0240540.
41. Fujiki S, Iijima K, Okabe M, Niwano S, Tsujita K, Naito S, Ando K, Kusano K, Kato R, Nitta J, Miura T, Mitsuhashi T, Kario K, Kondo Y, Ieda M, Hagiwara N, Murohara T, Takahashi K, Tomita H, Takeishi Y, Anzai T, Shimizu W, Watanabe M, Morino Y, Kato T, Tada H, Nakagawa Y, Yano M, Maemura K, Kimura T, Yoshida H, Ota K, Tanaka T, Kitamura N, Node K, Aizawa Y, Shimizu I, Izumi D, Ozaki K, Minamino T; EMPA-ICD investigators. Placebo-Controlled, Double-Blind Study of Empagliflozin (EMPA) and Implantable Cardioverter-Defibrillator (EMPA-ICD) in Patients with Type 2 Diabetes (T2DM): Rationale and Design. Diabetes Ther. 2020; 11(11): 2739-2755.
42. Shirakawa K, Endo J, Kataoka M, Katsumata Y, Anzai A, Moriyama H, Kitakata H, Hiraide T, Ko S, Goto S, Ichihara G, Fukuda K, Minamino T, Sano M. MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin-Producing Reparative Macrophages After Myocardial Infarction. J Am Heart Assoc. 2020; 9(18): e017071.
43. Kim HK, Ko TH, Song IS, Jeong YJ, Heo HJ, Jeong SH, Kim M, Park NM, Seo DY, Kha PT, Kim SW, Lee SR, Cho SW, Won JC, Youm JB, Ko KS, Rhee BD, Kim N, Cho KI, Shimizu I, Minamino T, Ha NC, Park YS, Nilius B, Han J. BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes. Life Sci Alliance. 2020; 3(9):e201900619.
44. Sakai R, Ozaki K, Yamaguchi Y, Kubota N, Takano T, Okubo T, Kimura S, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Pulmonary Artery Sarcoma Diagnosed Using an Endovascular Catheter Forceps Biopsy. Intern Med. 2020; 59(17): 2149-2153.
45. Tahara N, Dobashi H, Fukuda K, Funauchi M, Hatano M, Ikeda S, Joho S, Kihara Y, Kondo T, Matsushita M, Minamino T, Nakanishi N, Okano Y, Ozaki Y, Saji T, Sakai S, Tanabe N, Watanabe H, Yamada H, Yoshioka K, Hatta M, Sasayama S. Long-term treatment of pulmonary arterial hypertension with macitentan in Japanese patients. Curr Med Res Opin. 2020; 36(6): 921-928.
46. Takano T, Ozaki K, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Angioscopic findings during balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension Cardiovasc Interv Ther. 2020; 35(4): 421-422.
47. Sueta D, Tabata N, Ikeda S, Saito Y, Ozaki K, Sakata K, Matsumura T, Yamamoto-Ibusuki M, Murakami Y, Jodai T, Fukushima S, Yoshida N, Kamba T, Araki E, Iwase H, Fujii K, Ihn H, Kobayashi Y, Minamino T, Yamagishi M, Maemura K, Baba H, Matsui K, Tsujita K*. Differential predictive factors for cardiovascular events in patients with or without cancer history. Medicine (Baltimore). 2019; 98(44): e17602. (IF=1.870, CI=1)
48. Mori Y, Yamawaki K, Ishiguro T, Yoshihara K, Ueda H, Sato A, Ohata H, Yoshida Y, Minamino T, Okamoto K, Enomoto T*. ALDH-Dependent glycolytic activation mediates stemness and paclitaxel resistance in patient-derived spheroid models of uterine endometrial cancer. Stem Cell Reports. 2019; 13(4): 730-746. (IF=5.499, CI=0)
49. Okura Y*, Ozaki K, Tanaka H, Takenouchi T, Sato N, Minamino T. The impending epidemic of cardiovascular diseases in patients with cancer in Japan. Circ J. 2019; 83: 2191-2202. (IF=3.025, CI=0)
50. Sato A, Hasegawa Y, Haniu H, Shiraishi S, Yagihara N, Iijima K, Izumi D, Minamino T. Replacement of an Implantable Cardioverter-Defibrillator (ICD) with a New Standard Subcutaneous ICD System in a Patient with Jervell and Lange-Nielsen Syndrome. Int Heart J. 2019; 60(5): 1206-1210.
51. Kim HK, Jeon J, Song IS, Heo HJ, Jeong SH, Long LT, Thu VT, Ko TH, Kim M, Kim N, Lee SR, Yang JS, Kang MS, Ahn JM, Cho JY, Ko KS, Rhee BD, Nilius B, Ha NC, Shimizu I, Minamino T, Cho KI, Park YS, Kim S, Han J*. Tetrahydrobiopterin enhances mitochondrial biogenesis and cardiac contractility via stimulation of PGC1α signaling. Biochim Biophys Acta Mol Basis Dis. 2019; 1865: 165524. (IF=4.328, CI=0)
52. Okura Y*, Takayama T, Ozaki K, Tanaka H, Kikuchi A, Saito T, Tanigawa T, Takii Y, Seki H, Takenouchi T, Chou T, Sato N, Tanabe N, Minamino T. Future projection of cancer patients with cardiovascular disease in Japan by the year 2039: a pilot study. Int J Clin Oncol. 2019; 24(8): 983-994. (IF=2.503, CI=2)
53. Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T*. Prolyl isomerase Pin1 suppresses thermogenic programs in adipocytes by promoting degradation of transcriptional co-activator PRDM16. Cell Rep. 2019; 26: 3221-3230. (IF=7.815, CI=1)
54. Yokoyama M, Shimizu I, Nagasawa A, Yoshida Y, Katsuumi G, Wakasugi T, Hayashi Y, Ikegami R, Suda M, Ota Y, Okada S, Fruttiger M, Kobayashi Y, Tsuchida M, Kubota Y, Minamino T*. p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia. J Mol Cell Cardiol. 2019; 129: 105-117. (IF=5.055, CI=7)
55. Wakasugi T, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Nakao M, Hoyano M, Kashimura T, Nakamura K, Ito H, Nojiri T, Soga T, Minamino T*. Role of smooth muscle cell p53 in pulmonary arterial hypertension. PLoS One. 2019; 14: e0212889. (IF=2.776, CI=1)
56. Yoshida Y, Shimizu I, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Wakasugi T, Nakao M, Nakagami H, Morishita R, Minamino T*. Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity. Sci Rep. 2019; 9: 3858. (IF=4.011, CI=0)
57. Hasegawa Y*, Watanabe H, Ikami Y, Otsuki S, Iijima K, Yagihara N, Sato A, Izumi D, Minamino T. Early repolarization and risk of lone atrial fibrillation. J Cardiovasc Electrophysiol. 2019; 30: 565-568. (IF=2.910, CI=1)
58. Ikegami R, Shimizu I, Sato T, Yoshida Y, Hayashi Y, Suda Ma, Katsuumi G, Li J, Wakasugi T, Minokoshi Y, Okamoto S, Hinoi E, Nielsen S, Zenius Jespersen N, Scheele C, Soga T, Minamino T*. Gamma-aminobutyric acid signaling in brown adipose tissue promotes systemic metabolic derangement in obesity. Cell Rep. 2018: 24: 2827-2837. (IF=7.815, CI=4)
59. Takano T, Tanaka K*, Ozaki K, Sato A, Iijima K, Yanagawa T, Izumi D, Ozawa T, Fuse K, Sato M, Tanabe N, Minamino T. Clinical predictors of recurrent ventricular arrhythmias in secondary prevention implantable cardioverter defibrillator recipients with coronary artery disease-Lower left ventricular ejection fraction and incomplete revascularization. Circ J. 2018; 82: 3037-3043. (IF=3.025, CI=1)
60. Teratani T, Tomita K*, Suzuki T, Furuhashi H, Irie R, Nishikawa M, Yamamoto J, Hibi T, Miura S, Minamino T, Oike Y, Hokari R, and Kanai T. Aortic carboxypeptidase–like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis. J Clin Invest. 2018; 128: 1581-1596. (IF=12.282, CI=7)
61. Otuki S, Izumi D, Suda M, Sato A, Hasegawa Y, Yagihara N, Iijima K, Chinushi M, Fuse I, Minamino T*. Effects of direct oral anticoagulants at the peak phase, the trough phase, and after vascular injury. J Am Coll Cardiol. 2018; 71: 102-104. (IF=18.639, CI=4)
62. Si S, Nakajima-Takagi Y, Iga T, Tsuji M, Hou L, Oshima M, Koide S, Saraya A, Yamazaki S, Takubo K, Kubota Y, Minamino T*, Iwama A. Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells. Exp Hematol. 2018; 63: 41-51. (IF=2.462, CI=4)
63. Furuuchi R, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Wakasugi T, Nakao M, Minamino T*. Boysenberry polyphenol inhibits endothelial dysfunction and improves vascular health. PLoS One. 2018; 13: e0202051. (IF=2.776, CI=3)
64. Okura Y*, Ishigaki S, Sakakibara S, Yumoto C, Hashitate M, Sekine C, Fujita T, Takayama T, Ozaki K, Sato N, Minamino T. Prognosis of cancer patients with aortic stenosis under optimal cancer therapies and conservative cardiac treatments. Int Heart J. 2018; 59: 750-758. (IF=2.226, CI=5)
65. Kayamori H, Shimizu I, Yoshida Y, Hayashi Y, Suda M, Ikegami R, Katsuumi G, Wakasugi T, Minamino T*. Amlodipine inhibits vascular cell senescence and protects against atherogenesis through the mechanism independent of calcium channel blockade. Int Heart J. 2018; 59: 607-613. (IF=2.226, CI=1)
66. Katsuumi G, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Wakasugi T, Nakao M, Minamino T*. Catecholamine-induced senescence of endothelial cells and bone marrow cells promotes cardiac dysfunction in mice. Int Heart J. 2018; 59: 837-844. (IF=2.226, CI=4)
67. Ozawa T*, Suda M, Ikegami R, Takano T, Wakasugi T, Yanagawa T, Tanaka K, Ozaki K, Hirono S, Minamino T. Dual antiplatelet therapy guided by CYP2C19 polymorphisms after implantation of second-generation drug-eluting stents for management of acute coronary syndrome. Int Heart J. 2018; 59: 21-26. (IF=2.226, CI=4)
68. Suda M, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Katsuumi G, Wakasugi T, Yoshida Y, Okuda S, Soga T, Minamino T*. Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway. PLoS One. 2017; 12: e0182422. (IF=2.776, CI=6)
69. Kinoshita D, Nagasawa A, Shimizu I, Ito T, Yohko Y, Tsuchida M, Iwama A, Hayano T and Minamino T*. Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway. Oncotarget 2017; 8: 34045-34056. (CI=5.618, CI=11)
70. Nishiuchi S, Makiyama T*, Aiba T, Nakajima K, Hirose S, Kohjitani H, Yamamoto Y, Harita T, Hayano M, Wuriyanghai Y, Chen J, Sasaki K, Yagihara N, Ishikawa T, Onoue K, Murakoshi N, Watanabe I, Ohkubo K, Watanabe H, Ohno S, Doi T, Shizuta S, Minamino T, Saito Y, Oginosawa Y, Nogami A, Aonuma K, Kusano K, Makita N, Shimizu W, Horie M, Kimura T. Gene-based risk stratification for cardiac disorders in LMNA mutation carriers. Circ Cardiovasc Genet. 2017; 10. pii: e001603. doi:10.1161/CIRCGENETICS.116.001603. (IF=4.897, CI=16)
71. Aoyama N*, Nishinari M, Ohtani S, Kanai A, Noda C, Hirata M, Miyamoto A, Watanabe M, Minamino T, Izumi T, Ako J. Clinical features and predictors of patients with critical limb ischemia who responded to autologous mononuclear cell transplantation for therapeutic angiogenesis. Heart Vessels. 2017; 32: 1099-1108. (IF=1.620, CI=5)
72. Sonoda K, Ohno S, Otuki S, Kato K, Yagihara N, Watanabe H, Makiyama T, Minamino T, Horie M*. Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion. Europace. 2017; 19: 644-650. (IF=5.231, CI=7)
73. Otuki S*, Hasegawa K, Watanabe H, Katsuumi G, Yagihara N, Iijima K, Sato A, Izumi D, Furushima H, Chinushi M, Aizawa Y, Minamino T. The effects of pure potassium channel blocker nifekalant and sodium channel blocker mexiletine on malignant ventricular tachyarrhythmias. J Electrocardiol. 2017; 50: 277-281. (IF=1.166, CI=4)
74. Yagihara N, Watanabe H, Barnett P, Duboscq-Bidot L, Thomas AC, Yang P, Ohno S, Hasegawa K, Kuwano R, Chatel S, Redon R, Schott JJ, Probst V, Koopmann TT, Bezzina CR, Wilde AA, Nakano Y, Aiba T, Miyamoto Y, Kamakura S, Darbar D, Donahue BS, Shigemizu D, Tanaka T, Tsunoda T, Suda M, Sato A, Minamino T, Endo N, Shimizu W, Horie M, Roden DM, Makita N*. Variants in the SCN5A promoter associated with various arrhythmia phenotypes. J Am Heart Assoc. 2016; 5. doi: 10.1161/JAHA.116.003644. (IF=4.660, CI=7)
75. Hasegawa K, Watanabe H, Hisamatsu T, Ohno S, Itoh H, Ashihara T, Hayashi H, Makiyama T, Minamino T, Horie M*. Early repolarization and risk of arrhythmia events in long QT syndrome. Int J Cardiol. 2016; 223: 540-542. (IF=3.471, CI=5)
76. Ozaki K*, Okubo T, Tanaka K, Hosaka Y, Tsuchida K, Takahashi K, Oda H, Minamino T. Manifestation of latent left ventricular outflow tract obstruction in the acute phase of Takotsubo cardiomyopathy. Intern Med. 2016; 55: 3413-3420. (IF=0.956, CI=2)
77. Tahara N, Dobashi H, Fukuda K, Funauchi M, Hatano M, Ikeda S, Joho S, Kihara Y, Kimura T, Kondo T, Matsushita M, Minamino T, Nakanishi N, Ozaki Y, Saji T, Sakai S, Tanabe N, Watanabe H, Yamada H, Yoshioka K, Sasayama S*. Efficacy and safety of a novel endothelin receptor antagonist, macitentan, in Japanese patients with pulmonary arterial hypertension. Circ J. 2016; 80: 1478-1483. (IF=3.025, CI=5)
78. Watanabe T, Kashimura T*, Kodama M, Tanaka K, Fujiki S, Hayashi Y, Obata H, Hanawa H, Minamino T. Failing left ventricles have an enhanced post-stimulation potentiation despite their impaired force frequency relationship. Int Heart J. 2016; 57: 317-322. (IF=2.226, CI=0)
79. Sonoda K*, Watanabe H, Hisamatsu T, Ashihara T, Ohno S, Hayashi H, Horie M, Minamino T. High Frequency of early repolarization and Brugada-type electrocardiograms in hypercalcemia. Ann Noninvasive Electrocardiol. 2016; 21: 30-40. (IF=1.235, CI=3)
80. Higashi Y*, Azuma N, Takeishi Y, Minamino T, Kihara Y, Node K, Sata M, Fukumoto Y, Origasa H, Matsuo H, Naritomi H, Fujita M, Shimizu W. Effect of a low-Intensity pulsed ultrasound device, SX-1001, on clinical symptoms in Buerger disease with limb ischemia. Int Heart J. 2015; 56: 632-638. (IF=2.226, CI=1)
81. Hayashi Y, Hanawa H*, Jiao S, Hasegawa G, Ohno Y, Yoshida K, Suzuki T, Kashimura T, Obata H, Tanaka K, Watanabe T, Minamino T. Elevated endomyocardial biopsy macrophage-related markers in intractable myocardial diseases. Inflammation 2015; 38: 2288-2299. (IF=2.939, CI=7)
82. Yoshida Y, Shimizu I, Katsuumi G, Jiao S, Suda M, Hayashi Y, Minamino T*. p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload. J Mol Cell Cardiol. 2015; 85: 183-198. (IF=5.055, CI=24)
83. Iijima K*, Chinushi M, Saitoh O, Hasegawa K, Sonoda K, Yagihara N, Sato A, Izumi D, Watanabe H, Furushima H, Aizawa Y, Minamino T. Frequency characteristics and associations with the defibrillation threshold of ventricular fibrillation in patients with implantable cardioverter defibrillators. Intern Med. 2015; 54: 1175-1182. (IF=0.956, CI=1)
84. Takayama T, Okura Y*, Okada Y, Honma K, Nashimoto A, Sato N, Yokoyama A, Minamino T. Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients. Int J Clin Oncol. 2015; 20: 872-877. (IF=2.503, CI=6)
85. Ohno Y, Hanawa H*, Jiao S, Hayashi Y, Yoshida K, Suzuki T, Kashimura T, Obata H, Tanaka K, Watanabe T, Minamino T. Liver congestion in heart failure contributes to inappropriately increased serum hepcidin despite anemia. Tohoku J Exp Med. 2015; 235: 69-79. (IF=1.584, CI=4)
86. Nagao S, Watanabe H*, Sobue Y, Kodama M, Tanaka J, Tanabe N, Suzuki E, Narita I, Watanabe E, Aizawa Y, Minamino T. Electrocardiographic abnormalities and risk of developing cardiac events in extracardiac sarcoidosis. Int J Cardiol. 2015; 189: 1-5. (IF=3.471, CI=12)
87. Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I*. Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling. Nat Commun. 2015; 6: 6241. (IF=11.878, CI=23)
88. Suzuki H, Kayama Y*, Sakamoto M, Iuchi H, Shimizu I, Yoshino T, Katoh D, Nagoshi T, Tojo K, Minamino T, Yoshimura M, Utsunomiya K. Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of Diabetic Cardiomyopathy. Diabetes 2015; 64: 618-630. (IF=7.199, CI=56)
89. Nakagomi A, Okada S, Yokoyama M, Yoshida Y, Shimizu I, Miki T, Kobayashi Y, Minamino T*. Role of the central nervous system and adipose tissue BDNF/TrkB axes in metabolic regulation. NPJ Aging Mech Dis. 2015; 1: 15009. (CI=9)
90. Ito TK, Yokoyama M, Yoshida Y, Nojima A, Kassai H, Oishi K, Okada S, Kinoshita D, Kobayashi Y, Fruttiger M, Aiba A, Minamino T*. A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis. PLoS One 2014; 9: e102186. (IF=2.776, CI=16)
91. Kitada K*, Nakano D, Ohsaki H, Hitomi H, Minamino T, Yatabe J, Felder RA, Mori H, Masaki T, Kobori H, Nishiyama A. Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy. J Diabetes Complications 2014; 28: 604-611. (IF=2.684, CI=44)
92. Yoshida Y, Hayashi Y, Suda M, Tateno K, Okada S, Moriya J, Yokoyama M, Nojima A,Yamashita M, Kobayashi Y, Shimizu I, Minamino T*. Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway. PLoS One 2014; 9: e100359. (IF=2.776, CI=16)
93. Hamada N*, Fujimichi Y, Iwasaki T, Fujii N, Furuhashi M, Kubo E, Minamino T, Nomura T, Sato H. Emerging issues in radiogenic cataracts and cardiovascular disease. J Radiat Res. 2014; 55: 831-846. (IF=2.014, CI=40)
94. Yokoyama M, Nakagomi A, Moriya J, Shimizu I, Nojima A, Yoshida Y, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Fruttiger M, Lozano G, Minamino T*. Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity. Cell Rep. 2014; 7: 1691-1703. (IF=7.815, CI=37)
95. Maida Y, Yasukawa M, Okamoto N, Ohka S, Kinoshita K, Totoki Y, Ito TK, Minamino T, Nakamura H, Yamaguchi S, Shibata T, Masutomi K*. Involvement of TERT in heterochromatin maintenance. Mol Cell Biol. 2014; 34: 1576-1593. (IF=3.735, CI=21)
96. Katsuumi G, Shimizu W, Watanabe H*, Noda T, Nogami A, Ohkubo K, Makiyama T, Takehara N, Kawamura Y, Hosaka Y, Sato M, Fukae S, Chinushi M, Oda H, Okabe M, Kimura A, Maemura K, Watanabe I, Kamakura S, Horie M, Aizawa Y, Makita N, Minamino T. Efficacy of bepridil to prevent ventricular fibrillation in severe form of early repolarization syndrome. Int J Cardiol. 2014; 172: 519-522. (IF=3.471, CI=4)
97. Suzuki T, Hanawa H*, Jiao S, Ohno Y, Hayashi Y, Yoshida K, Kashimura T, Obata H, Minamino T. Inappropriate expression of hepcidin by liver congestion contributes to anemia and relative iron deficiency. J Card Fail. 2014; 20: 268-277. (IF=3.967, CI=14)
98. Kashimura T*, Kodama M, Watanabe T, Tanaka K, Hayashi Y, Ohno Y, Obata H, Ito M, Hirono S, Hanawa H, Minamino T. Relative refractoriness of left ventricular contraction underlies human tachycardia-induced mechanical and electrical alternans. Pacing Clin Electrophysiol. 2014; 37: 197-206. (IF=1.340, CI=3)
99. Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, Minamino T, Hirose K, Nakajima H*. Tumor suppresser p53 inhibits systemic autoimmune diseases by inducing regulatory T cells. J Immunol. 2013; 191: 3614-3623. (IF=4.718, CI=34)
100. Ozasa Y, Akazawa H, Qin Y, Tateno K, Ito K, Kudo-Sakamoto Y, Yano M, Yabumoto C, Naito AT, Oka T, Lee JK, Minamino T, Nagai T, Kobayashi Y, Komuro I*. Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cell. Hypertens Res. 2013; 36: 859-865. (IF=3.217, CI=26)
101. Shimizu I, Yoshida Y, Moriya J, Nojima A, Uemura A, Kobayashi Y, Minamino T*. Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity. Cell Metab. 2013; 18: 491-504. (IF=22.415, CI=58)
102. Bezzina CR*, Barc J, Mizusawa Y, Ann Remme C, Gourraud J-B, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Salling Olesen M, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden D, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott J-J, Dina C, Redon R. Common variants at the SCN5A/SCN10A and HEY2 loci predispose to Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet. 2013; 45: 1044-1049. (IF=25.455, CI=249)
103. Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Naoaki I, Minamino T*. Haploinsufficiency of Akt1 prolongs the lifespan of mice. PLoS One 2013; 8: e69178. (IF=2.776, CI=33)
104. Sato A*, Chinushi M, Izumi D, Furushima H, Minamino T. Malfunction of cardiac resynchronization therapy due to subsequent fracture of the ring and tip conductors of a co-radial left ventricular bipolar lead. Intern Med. 2013; 52: 1189-1193. (IF=0.956, CI=0)
105. Watanabe H, van der Werf C, Roses-Noguer F, Adler A, Sumitomo N, Veltmann C, Rosso R, Bhuiyan ZA, Bikker H, Kannankeril PJ, Horie M, Minamino T, Viskin S, Knollmann BC, Till J, Wilde AA*. Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm 2013; 10: 542-547. (IF=5.225, CI=55)
106. Tomita K*, Teratani T, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Nishiyama K, Mataki N, Irie R, Minamino T, Okada Y, Kurihara C, Ebinuma H, Saito H, Shimizu I, Yoshida Y, Hokari R, Sugiyama K, Hatsuse K, Yamamoto J, Kanai T, Miura S, Hibi Tp53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice. J Hepatol. 2012; 57: 837-843. (IF=18.946, CI=43)
107. Okada S, Yokoyama M, Toko H, Tateno K, Moriya J, Shimizu I, Nojima A, Ito T, Yoshida Y, Kobayashi Y, Katagiri H, Minamino T, Komuro I*. Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol. 2012; 32: 1902-1909. (IF=6.618, CI=66)
108. Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I*. Complement C1q activates canonical Wnt signaling and promotes age-related phenotypes. Cell 2012; 149: 1298-1313. (IF=36.216, CI=134)
109. Yasuda N, Akazawa H, Ito K, Shimizu I, Kudo-Sakamoto Y, Yabumoto C, Yano M, Yamamoto R, Ozasa Y, Minamino T, Naito AT, Oka T, Shiojima I, Tamura K, Umemura S, Nemer M, Komuro I*. Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice. Hypertension 2012; 59: 627-633. (IF=7.017, CI=27)
110. Shimizu I, Yoshida Y, Katsuno T, Tateno K, Okada S, Moriya J, Yokoyama M, Nojima A, Ito T, Zechner R, Komuro I, Kobayashi Y, Minamino T*. p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure. Cell Metab. 2012; 15: 51-64. (IF=22.415, CI=94)
111. Nakano D*, Lei B, Kitada K, Hitomi H, Kobori H, Mori H, Deguchi K, Masaki T, Minamino T, Nishiyama A. Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. Am J Hypertens. 2012; 25: 354-358. (IF=2.530, CI=3)
112. Odaka K, Aoki I*, Moriya J, Tateno K, Tadokoro H, Kershaw J, Minamino T, Irie T, Fukumura T, Komuro I, and Saga T. In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging. PLoS One 2011; 6: e25487. (IF=2.776, CI=5)
113. Wu X, Zou Y, Zhou Q, Huang L, Gong H, Sun A, Tateno K, Katsube K, Radtke F, Ge J, Minamino T, Komuro I*. Role of JAGGED1 in arterial lesions after vascular injury. Arterioscler Thromb Vasc Biol. 2011; 31: 2000-2006. (IF=6.618, CI=23)
114. Toko H, Takahashi H, Kayama Y, Oka T, Minamino T, Okada S, Morimoto S, Zhan DY, Terasaki F, Anderson ME, Inoue M, Yao A, Nagai R, Kitaura Y, Sasaguri T, Komuro I*. Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy. Circulation 2010; 122: 891-899. (IF=23.054, CI=64)
115. Toko H, Takahashi H, Kayama Y, Okada S, Minamino T, Terasaki F, Kitaura Y, and Komuro I*. ATF6 is important under both pathological and physiological states in the heart. J Mol Cell Cardiol. 2010; 49:113-20. (IF=5.055, CI=48)
116. Naito AT, Okada S, Minamino T, Iwanaga K, Liu M, Sumida T, Nomura S, Sahara N, Mizoroki T, Takashima A, Akazawa H, Nagai T, Shiojima I, Komuro I*. Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury. Circ Res. 2010; 106 :1692-1702. (IF=15.862, CI=85)
117. Shimizu I, Minamino T**, Toko H, Okada S, Ikeda H, Yasuda N, Tateno K, Moriya J, Yokoyama M, Nojima A, Koh GY, Akazawa H, Shiojima I, Kahn CR, Abel ED and Komuro I*. Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload. J Clin Invest. 2010; 120 :1506-1514. (**Co-first author) (IF=12.282, CI=109)
118. Moriya J, Minamino T**, Tateno K, Okada S, Uemura A, Shimizu I, Yokoyama M, Nojima A, Okada M, Koga H, Komuro I*. Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis. Circ Res. 2010; 106: 391-398. (**Co-first author) (IF=15.862, CI=44)
119. Minamino T, Orimo M, Shimizu I, Kunieda T, Yokoyama M, Ito T, Nojima A, Nabetani A, Oike Y, Matsubara H, Ishikawa F, Komuro I*. A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med. 2009; 15: 1082-1087. (IF=30.641, CI=393)
120. Kayama Y, Minamino T**, Toko H, Sakamoto M, Shimizu I, Takahashi H, Okada S, Tateno K, Moriya J, Yokoyama M, Nojima A, Yoshimura M, Egashira K, Aburatani H and Komuro I*. Cardiac 12/15-lipoxygenase-induced inflammation is involved in heart failure. J Exp Med. 2009; 206: 1565-1574. (**Co-first author) (IF=10.892, CI=71)
121. Moriya J, Minamino T**, Tateno K, Shimizu N, Kuwabara Y, Sato Y, Saito Y and Komuro I*. Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia. Circ Cardiovasc Intervent. 2009; 2: 245-254. (**Co-first author) (IF=6.088, CI=62)
122. Orimo M, Minamino T**, Miyauchi H, Tateno K, Okada S, Moriya J, Komuro I*. Protective role of SIRT1 in diabetic vascular dysfunction. Arterioscler Thromb Vasc Biol. 2009; 29: 889-894. (*Co-first author) (IF=6.618, CI=142)
123. Nishi J, Minamino T**, Miyauchi H, Nojima A, Tateno K, Okada S, Orimo M, Moriya J, Fong GH, Sunagawa K, Shibuya M, Komuro I*. Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt. Circ Res 2008; 103: 261-268. (**Co-first author) (IF=15.862, CI=40)
124. Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M and Komuro I*. IGFBP-4 is an inhibitor of canonical Wnt signaling required for cardiogenesis. Nature 2008; 454:345-349. (IF= 43.070, CI=158)
125. Kunieda T, Minamino T**, Miura K, Katsuno T, Tateno K, Miyauchi H, Kaneko S, Bradfield CA, FitzGerald GA, Komuro I*. Reduced nitric oxide causes age-associated impairment of circadian rhythmicity. Circ Res. 2008; 102: 607-614. (**Co-first author) (IF=15.862, CI=72)
126. Sano M, Minamino T**, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin J D, Zou Y and Komuro I*. p53-induced Inhibition of hif-1 causes cardiac dysfunction during pressure overload. Nature 2007; 446: 444-448. (**Co-first author) (IF=43.070, CI=587)
127. Sakamoto M, Minamino T, Toko H, Kayama Y, Zou Y, Sano M, Takaki E, Aoyagi T, Tojo K, Tajima N, Nakai A, Aburatani H, Komuro I*. Upregulation of Heat Shock Transcription Factor 1 Plays a Critical Role in Adaptive Cardiac Hypertrophy. Circ Res. 2006; 99: 1411-1418. (IF=15.862, CI=70)
128. Kunieda T, Minamino T**, Nishi J, Tateno K, Oyama T, Katsuno T, Miyauchi H, Orimo M, Okada S, Takamura M, Nagai T, Kaneko S and Komuro I*. Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway. Circulation 2006; 114: 953-960. (**Co-first author) (IF=23.054, CI=174)
129. Tateno K, Minamino T**, Toko H, Akazawa H, Shimizu N, Takeda S, Kunieda T, Miyauchi H, Oyama T, Matsuura K, Nishi JI, Kobayashi Y, Nagai T, Kuwabara Y, Iwakura Y, Nomura F, Saito Y, Komuro I*. Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization. Circ Res. 2006; 98: 1194-1202. (**Co-first author) (IF=15.862, CI=139)
130. Kunieda T, Minamino T, Katsuno T, Tateno K, Nishi JI, Miyauchi H, Orimo M, Okada S, Komuro I*. Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res. 2006; 98: 532-539. (IF=15.862, CI=72)
131. Naito AT, Akazawa H, Takano H, Minamino T, Nagai T, Aburatani H, Komuro I*. Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling. Circ Res. 2005; 22: 144-151. (IF=15.862, CI=90)
132. Harada M, Qin Y, Takano H, Minamino T**, Zou Y, Toko H, Ohtsuka M, Matsuura K, Sano M, Nishi J, Iwanaga K, Akazawa H, Kunieda T, Zhu W, Hasegawa H, Kunisada K, Nagai T, Nakaya H, Yamauchi-Takihara K, Komuro I*. G-CSF prevents cardiac remodeling after myocardial infarction by activating Jak/Stat in cardiomyocytes. Nat Med. 2005; 11: 305-311. (**Co-first author) (IF=30.641, CI=475)
133. Matsuura K, Wada H, Nagai T, Iijima Y, Minamino T, Sano M, Akazawa H, Molkentin JD, Kasanuki H, Komuro I*. Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle. J Cell Biol. 2004; 167: 351-363. (IF=8.891, CI=100)
134. Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T, Makita N, Iwanaga K, Zhu W, Kudoh S, Toko H, Tamura K, Kihara M, Nagai T, Fukamizu A, Umemura S, Iiri T, Fujita T, Komuro I*. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol. 2004; 6: 499-506. (IF=17.728, CI=453)
135. Toko H, Zou Y, Minamino T, Sakamoto M, Sano M, Harada M, Nagai T, Sugaya T, Terasaki F, Kitaura Y, Komuro I*. Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium. Arterioscler Thromb Vasc Biol. 2004; 24: 664-670. (IF=6.618, CI=35)
136. Miyauchi H, Minamino T*, Tateno K, Kunieda T, Toko H, Komuro I*. Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway. EMBO J. 2004; 23 212–220. (*Co-first author) (IF=11.227, CI=235)
137. Zou Y, Zhu W, Sakamoto M, Qin Y, Akazawa H, Toko H, Mizukami M, Takeda N, Minamino T, Takano H, Nagai T, Nakai A, Komuro I*. Heat shock transcription factor 1 protects cardiomyocytes from ischemia/reperfusion injury. Circulation 2003; 108: 3024-3030. (IF=23.054, CI=60)
138. Minamino T, Yoshida T, Tateno K, Miyauchi H, Zou Y, Toko H, Komuro I*. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 2003; 108: 2264-2269. (IF=23.054, CI=145)
139. Zou Y, Takano H, Mizukami M, Akazawa H, Qin Y, Toko H, Sakamoto M, Minamino T, Nagai T, Komuro I*. Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration of myocardium after myocardial infarction. Circulation 2003; 108: 748-753. (IF=23.054, CI=76)
140. Zampetaki A, Minamino T, Mitsialis SA, Kourembanas S*. Effect of heme oxygenase-1 overexpression in two models of lung inflammation. Exp Biol Med. 2003; 228: 442-446. (IF=3.005, CI=53)
141. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I*. Endothelial cell senescence in human atherosclerosis. J Cardiol. 2003; 41: 39-40. (IF=2.289, CI=19)
142. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I*. Endothelial cell senescence in human atherosclerosis. Role of telomere in endothelial dysfunction. Circulation. 2002; 105: 1541-1544. (IF=23.054, CI=627)
143. Minamino T, Toko H, Tateno K, Nagai T, Komuro I*. Peripheral-blood or bone-marrow mononuclear cells for therapeutic angiogenesis? Lancet 2002; 360:2083-2084. (IF=59.102, CI=62)
144. Minamino T, Christou H, Hsieh C-M, Liu Y, Dhawan V, Abraham NG, Perrella MA, Mitsialis SA and Kourembanas S*. Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci USA. 2001; 98:8798-8803. (IF=9.580, CI=303)
145. Minamino T and Kourembanas S*. Mechanisms of telomerase induction during vascular smooth muscle cell proliferation. Circ Res. 2001; 89:237-243. (IF=15.862, CI=66)
146. Minamino T, Mitsialis SA and Kourembanas S*. Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation. Mol Cell Biol 2001; 21:3336-3342. (IF=3.735, CI=137)
147. Morita H, Taguchi J, Kurihara H*, Kitaoka M, Kaneda H, Kurihara Y, Maemura K, Shindo T, Minamino T, Ohno M, Yamaoki K, Ogasawara K, Aizawa T, Suzuki S and Yazaki Y. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase as a risk factor for coronary artery disease. Circulation 1997; 95:2032-2036. (IF=23.054, CI=301)
148. Morita H, Kaneda H, Kurihara Y*, Maemura K, Shindo T, Minamino T, Ohno M, Yamaoki K, Ogasawara K, Aizawa T, Suzuki S and Yazaki Y. Gene Polymorphism of 5,10-methylenetetrahydrofolate reductase as a coronary risk factor. J Cardiol. 1997; 29:309-315. (IF= 2.289, CI=18)
149. Minamino T, Kurihara H*, Takahashi M, Shimada K, Maemura K, Oda H, Ishikawa T, Uchiyama T, Tanzawa K and Yazaki Y. Endothelin converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis. Circulation 1997; 95: 221-230. (IF=23.054, CI=108)
150. Iwata H, Minamino T. Identification of a novel therapeutic target in vascular dysfunction: A showcase of reverse and forward translational research linking between bench and bedside. Eur Heart J. 2021 (in press).
151. Ito M, Matsue Y, Minamino T. Worsening renal function during intensive blood pressure control: another example of not prognostically relevant creatinine rise? Eur J Heart Fail. 2021 Mar;23(3):393-395.
152. Shimizu I, Minamino T. Cellular Senescence in Arterial Diseases. J Lipid Atheroscler. 2020; 9(1): 79-91.
153. Shimizu I, Minamino T*. Cellular senescence in cardiac diseases. J Cardiol. 2019; 74: 313-319. (IF=2.289, CI=4)
154. Ikegami R, Shimizu I, Yoshida Y, Minamino T*. Metabolomic analysis in heart failure. Circ J. 2018; 82: 10-16. (IF=3.025, CI=8)
155. Watanabe H*, Minamino T. Atrial fibrillation in patients with end-stage kidney disease on dialysis. Intern Med. 2018; 57: 2285-2286. (IF=0.956, CI=1)
156. Katsuumi G, Shimizu I, Yoshida Y, Minamino T*. Vascular senescence in cardiovascular and metabolic diseases. Front Cardiovasc Med. 2018; 5: 18. doi: 10.3389/fcvm.2018.00018. (CI=25)
157. Moriya J, Minamino T*. Angiogenesis, cancer, and vascular aging. Front Cardiovasc Med. 2017; 4: 65. (CI=11)
158. Watanabe H*, Minamino T. Rare variants in ANK2 associated with various inherited arrhythmia syndromes. Circ J. 2016; 80: 2423-2424. (IF=3.025, CI=0)
159. Shimizu I, Minamino T*. Physiological and pathological cardiac hypertrophy. J Mol Cell Cardiol. 2016; 97: 245-262. (IF=5.055, CI=198)
160. Watanabe H*, Minamino T. Genetics of Brugada syndrome. J Hum Genet. 2016; 61: 57-60. (IF=3.545, CI=31)
161. Shimizu I, Yoshida Y, Minamino T*. A role for circadian clock in metabolic disease. Hypertens Res. 2016; 39: 483-491. (IF=3.217, CI=17)
162. Katsuumi G, Shimizu I, Yoshida Y, Minamino T*. The pathological role of vascular aging in cardio-metabolic disorder. Inflamm Regen. 2016; 36: 16.
163. Shimizu I, Yoshida Y, Minamino T*. Maintenance of subcutaneous fat homeostasis improves systemic metabolic dysfunction in obesity. Diabetes 2015; 64: 3984-3986. (IF=7.199, CI=8)
164. Shimizu I, Yoshida Y, Minamino T*. Pathological role of adipose tissue dysfunction in cardio-metabolic disorders. Int Heart J. 2015; 56: 255-259. (IF=2.226, CI=7)
165. Yoshida Y, Shimizu I, Minamino T*. The pathological role of adipose tissue aging in the progression of systemic insulin resistance. Inflammation and regeneration 2015; 35: 178-184.
166. Shimizu I, Yoshida Y, Suda M, Minamino T*. DNA damage response and metabolic disease. Cell Metab. 2014; 20: 967-977. (IF=22.415, CI=84)
167. Shimizu I, Yoshida Y, Katsuno T, Minamino T*. Adipose tissue inflammation in diabetes and heart failure. Microbes and Infection 2013; 15: 11-17. (IF=2.699, CI=13)
168. Watanabe H*, Minamino T. Role of mutations in L-type calcium channel genes in Brugada syndrome, early repolarization syndrome, and idiopathic ventricular fibrillation associated with right bundle branch block. Circ J. 2013; 77: 1689-1690. (IF=3.025, CI=3)
169. Minamino T*. Role of cellular senescence in lifestyle-related disease Circ J. 2010; 74: 2527-2533. (IF=3.025, CI=10)
170. Minamino T*. Gap junctions mediate the spread of ischemia-reperfusion injury. Circ J. 2009; 73, 1591-1592. (IF=3.025, CI=6)
171. Minamino T and Komuro I*. Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes. Nat Rev Cardiol (Nat Clin Pract Cardiovasc Med). 2008; 5: 637-648. (IF= 17.420, CI=74)
172. Toko H, Minamino T, Komuro I*. Role of heat shock transcriptional factor 1 and heat shock proteins in cardiac hypertrophy. Trends Cardiovasc Med. 2008; 18: 88-93. (IF=4.462 CI=20)
173. Minamino T and Komuro I. Role of telomeres in vascular senescence. Front Biosci. 2008; 13: 2971-2979. (IF=3.736, CI=30)
174. Tateno K, Minamino T, Moriya J, Katada A, Yokoyama M, Miura K, Komuro I*. Cell therapy for cardiovascular diseases. Ann Vasc Dis 2008; 1: 66-79.
175. Minamino T and Komuro I*. Vascular cell senescence: Contribution to atherosclerosis. Circ Res. 2007; 100: 15-26. (IF=15.862, CI=374)
176. Minamino T and Komuro I*. Critical roles of insulin-induced senescence in diabetic vasculopathy. Vascular Disease Prevention 2007; 4: 194-200. (CI=0)
177. Minamino T, Komuro I*. Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury. J Clin Invest. 2006; 116: 2316-2319. (IF=12.282, CI=76)
178. Tateno K, Minamino T, Miyauchi H, Kunieda T, Komuro I*. Application of hematopoietic cells to therapeutic angiogenesis. Curr Pharm Des. 2006; 12: 557-563. (IF=2.412, CI=8)
179. Minamino T, Miyauchi H, Yoshida T, Tateno K and Komuro I*. The role of vascular cell senescence in atherosclerosis. Antisenescence as a novel therapeutic strategy for vascular aging. Curr Vasc Pharmacol. 2004; 2: 141-148. (IF=2.583, CI=39)
180. Minamino T, Miyauchi H, Tateno K, Kunieda T, Komuro I*. Akt-induced senescence: Impication for human disease. Cell Cycle 2004; 4: 449-451. (IF=3.259, CI=0)
181. Minamino T, Miyauchi H, Yoshida T, Tateno K, Kunieda T, Komuro I*. Vascular cell senescence and vascular aging. J Mol Cell Cardiol. 2004; 36:175-183. (IF=5.055, CI=114)
182. Minamino T and Komuro I*. The role of telomerase activation in the regulation of vascular smooth muscle cell proliferation. Drug News Perspect. 2003; 16:211-216. (IF=3.132, CI=9)
183. Minamino T and Komuro I*. Role of telomere in endothelial dysfunction in atherosclerosis. Curr Opin Lipidol. 2002; 13:537-543. (IF=4.844, CI=40)
Case reports:
184. Otsuki S, Izumi D, Hasegawa Y, Yagihara N, Iijima K, Minamino T. Suppression of cardiac memory-related severe form of torsades de pointes by landiolol in a patient with congenital long QT syndrome type 2. Heart Rhythm Case Rep. 2020; 6(7): 407-410.
185. Kubota H*, Endo H, Ishii H, Tsuchiya H, Inaba Y, Terakawa K, Takahashi Y, Noma M, Takemoto K, Taniai S, Sakata K, Soejima K, Shimoyamada H, Kamma H, Kawakami H, Kaneko Y, Hirono S, Izumi D, Ozaki K, Minamino T, Yoshino H, Sudo K. Adult ALCAPA: from histological picture to clinical features. J Cardiothorac Surg 2020; 15: 14. (IF=1.470, CI=0)
186. Takano T*, Ozaki K, Hoyano M, Yanagawa T, Kashimura T, Minamino T. Angioscopic findings during balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension. Cardiovasc Interv Ther 2020; 35(4): 421-422..
187. Sato A*, Yagihara N, Hasegawa Y, Otuki S, Iijima K, Izumi D, Minamino T. A steam pop detected by intracardiac echocardiography during catheter ablation of the left ventricular papillary muscle. Int Heart J. 2019; 60: 199-203. (IF=2.226, CI=0)
188. Hoyano M*, Ozaki K, Nishida K, Sakai R, Kubota N, Takano T, Okubo T, Kimura S, Yanagawa T, Ozawa T, Kashimura T, Minamino T. High-resolution angioscopy of endoluminal stent graft at 6 months after implantation. Circ J. 2019; 83: 1970. (IF=3.025, CI=0)
189. Sato A*, Hasegawa Y, Haniu H, Shiraishi S, Yagihara N, Iijima K, Izumi D, Minamino T. Replacement of an implantable cardioverter-defibrillator (ICD) with a newstandard subcutaneous ICD system in a patient with Jervell and Lange-Nielsen syndrome. Int Heart J. 2019; 60: 1206-1210. (IF=2.226, CI=0)
190. Takano T*, Ozaki K, Hoyano M, Yanagawa T, Ozawa T, Minamino T. Stent malapposition occurred 17 days following percutaneous coronary intervention for a severe calcified lesion in acute myocardial infarction. J Cardiol Cases. 2019; 20: 4-7. (CI=0)
191. Sato A,* Takano T, Chinushi M, Minamino T. Usefulness of the intravenous flecainide challenge test before oral flecainide treatment in a patient with Andersen-Tawil syndrome. BMJ Case Rep. 2019; 12. pii: e229628. (CI=1)
192. Kayamori H, Kashimura T*, Horii Y, Kanazawa T, Fujita T, Kubota N, Ikami Y, Takano T, Okubo T, Hoyano M, Yanagawa T, Ozawa T, Ozaki K, Minamino T. Bidirectional shunt trajectory in ventricular septal defect with Eisenmenger's syndrome. Circ J. 2018; 82: 2925-2926. (IF=3.025, CI=0)
193. Takano T*, Ozaki K, Tanaka K, Yanagawa T, Ozawa T, Minamino T. Efficacy of corticosteroid treatment for refractory multivessel vasospastic coronary angina with hypereosinophilia. Intern Med. 2018; 57: 3111-3115. (IF=0.956, CI=1)
194. Sakaguchi Y*, Ozaki K, Takano T, Namba H, Tanaka K, Yanagawa T, Ozawa T, Minamino T. Dynamic left ventricular outflow tract obstruction complicated with takotsubo cardiomyopathy: The acute phase of takotsubo cardiomyopathy manifests latent left ventricular outflow tract obstruction. J Cardiol Cases. 2018; 18: 60-64. (CI=0)
195. Ikegami R*, Ozaki K, Ozawa T, Hirono S, Ito M, Minamino T. Percutaneous Coronary intervention for a patient with left main coronary compression syndrome. Intern Med. 2018; 57: 1421-1424. (IF=0.956, CI=1)
196. Takayama T*, Ozawa T, Sanada A, Watanabe T, Ito M, Hirono S, Aizawa Y, Minamino T. Aortic regurgitation presenting with recurrent detachment of a prosthetic valve, as the first presenting symptom of cardiovascular Behçet's disease. Intern Med. 2018; 57: 823-827. (IF=0.956, CI=0)
197. Iijima K*, Ishida N, Izumi D, Minamino T. Inappropriate inhibition of biventricular pacing due to diaphragmatic myopotentials amplified by the selectable sensing filter. Europace. 2017; 19: 2014. (IF=5.231, CI=0)
198. Sato A*, Hasegawa Y, Minamino T. The first reported case of a transvenous left ventricular pacing lead of cardiac resynchronization therapy causing aggravation of coronary atherosclerosis. Europace. 2016; 18: 1734. (IF=5.231, CI=0)
199. Tagawa M*, Nanba H, Suzuki H, Nakamura Y, Uchiyama H, Ochiai S, Terunuma M, Yahata K, Minamino T. Ventricular rhythm and hypotension in a patient with pheochromocytoma-induced myocardial damage and reverse Takotsubo cardiomyopathy. Intern Med. 2015; 54: 2343-2349. (IF=0.956, CI=4)
200. Watanabe T*, Kashimura T, Obata H, Minamino T. Cibenzoline abolished pulsus alternans in a HOCM patient. Intern Med. 2015; 54: 2273. (IF=0.956, CI=0)
201. Suzuki H, Hoshina S, Ozawa J, Sato A, Minamino T, Aizawa Y, Saitoh A*. Short QT syndrome in a boy diagnosed on screening for heart disease. Pediatr Int 2014; 56: 774-776. (IF=0.939, CI=7)
202. Sato A*, Watanabe H, Sonoda K, Chinushi M, Tsuda T, Izumi D, Furushima H, Minamino T. Augmentation of the J wave by rapid pacing in a patient with vasospastic angina. Int J Cardiol. 2014; 172: e111-113. (IF=3.471, CI=3)
203. Watanabe H, Ohkubo K, Watanabe I, Matsuyama TA, Ishibashi-Ueda H, Yagihara N, Shimizu W, Horie M, Minamino T, Makita N*. SCN5A mutation associated with ventricular fibrillation, early repolarization, and concealed myocardial abnormalities. Int J Cardiol. 2013; 165: e21-23. (IF=3.471, CI=11)
204. Watanabe T, Hanawa H*, Suzuki T, Jiao S, Yoshida K, Ogura M, Ohno Y, Hayashi Y, Ito M, Kashimura T, Obata H, Sato A, Ozawa T, Kodama M, Sakuraba H, Minamino T. A mutant mRNA expression in an endomyocardial biopsy sample obtained from a patient with a cardiac variant of Fabry disease caused by a novel acceptor splice site mutation in the invariant AG of intron 5 of the α-galactosidase A gene. Intern Med. 2013; 52: 777-780. (IF=0.956, CI=5)
205. Narumi H, Funabashi N, Takano H, Sekine T, Ueda M, Hori Y, Fukawa T, Minamino T, Kobayashi Y, Komuro I*. Remarkable thickening of right atrial wall in subjects with cardiac amyloidosis complicated with sick sinus syndrome. Int J Cardiol. 2007; 119: 222-224. (IF=3.471, CI=12)
206. Uehara M, Funabashi N, Ogawa Y, Minamino T, Komuro I*. Double outlet right ventricle demonstrated by multislice computed tomography. Int J Cardiol. 2007; 121: 218-220. (IF=3.471, CI=13)
207. Naito AT, Minamino T, Tateno K, Nagai T, Komuro I*. Steroid-responsive thromboangiitis obliterans. Lancet 2004; 364: 1098. (IF=59.102, CI=8)
Books:
208. Katsuumi G, Minamino T. Cellular Senescence in Disease. 7. Vascular diseases. ii. Atherosclerosis. 2020 (in press) (Elsevier Textbook).
209. Suda M, Shimizu I, Yoshida Y, Katsuumi G, Minamino T. Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease. Endothelial cell dysfunction and Senescence: Biologic mechanisms and Hemodynamic consequences. 2020 (in press) (Elsevier Textbook).
210. Suda M, Shimizu I, Yoshida Y, Minamino T. Chapter 2. Peripheral Blood Mononuclear Cells for Limb Ischemia. 2017: 25–43. (Springer publication).
211. Yoshida Y, Shimizu I, Minamino T. Diabetes and adipocyte dysfunction. Diabetes and Aging-related Complications. 2017: 69-84. (Springer publication).
212. Minamino T, Komuro I. Vascular cell senescence in human atherosclerosis. In: Atherosclerosis XIII (edited by Yuji Matsuzawa, Toru Kita, Ryozo Nagai, and Tamio Teramoto), p566-569, ELSEVIER, Netherlands, 2004.

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南野 徹（ミナミノ トオル）

南野徹（ミナミノトオル）