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研究者詳細
| 区分 | 教員 |
|---|---|
| 学部・大学院 | 大学院医学研究科 |
| 所属 | 難病診断治療研究センター |
| 職名 | 特任先任准教授 |
| 氏名 | GUSEV OLEG（グセフ オレグ） |
| 連絡先住所 | |
| 電話番号 | |
| FAX番号 | |
| メールアドレス | o.gusev.fo@juntendo.ac.jp |
| 研究分野 | I got my PhD in genomics from Okayama University (2007). Our current research focus is on human genomics, gene expression regulation, biomimetic and biology of extremophiles. I am also actively involved in bridging the gap between basic science and disease-related research using multi-omics technologies. |
| 研究分野を表すキーワード | comparative genomics, transcriptomics, cross-omics technologies, NGS, biomimetics, developmental biology. |
| 出身学校、専攻等 | Kazan University, RU 2004年 |
| 出身大学院、研究科等 | Okayama University, JP 2004年 |
| 取得学位 | PhD in Regulatory Biology, Okayama University, 2007年 |
| 研究職歴 | 平成19年10月 農業・食品産業技術総合研究機構 JSPS Postdoctoral Fellow 平成21年11月 同 上 主任研究員 平成24年4月 宇宙航空研究開発機構 特任研究員 平成27年6月 理化学研究所予防医療診断技術開発プログラム マネジャー 平成28年8月 理化学研究所 理研－KFU応用ゲノム特別ユニット リーダー 平成30年4月 順天堂大学大学院医学科研究科 臨床オミックス研究コース 客員准教授 令和3年4月 順天堂大学院医学研究科 特任先任准教授 |
| 受賞学術賞 | Young Researcher Award Japan Society of Cytoprotection and Cytobiology (2014) Zeldovich Medal for Young Scientists by Committee on Space Research (COSPAR): Space Life Sciences (2010) Certificate of Appreciation by President of Japan Society for the Promotion of Science (2008, 2009) |
| 所属学会 | |
| 学位論文 | Petersen J., Englmaier L., Artemov A., Poverennaya I., Mahmoud R., Bouderlique T., Tesarova T., Deviatiiarov R.,Szilvásy-Szabó A.,E Akkuratov E., Reguera D., Hugo Zeberg, Kaucka M., Kastriti M.,Krivanek J.,Radaszkiewicz R., Gömöryová K., Knauth S., Potesil D., Zdrahal Z., Sri Ganji R., Grabowski A., Buhl M., Zikmund T., Kavkova M., Axelson H., Lindgren D., Kramann R., Kuppe Ch., Erdélyi F., Máté Z., Szabó G., Koehne G., Harkany T., Fried K.,Kaiser J., Boor P., Fekete C.,Rozman J., Kasparek P., Prochazka J., Sedlacek R., Bryja V.,Gusev O., Adameyko I. A previously uncharacterized factor associated with metabolism and energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology. Nature Commun. 2023. 14, 3092. IF: 17.6/CI:0 Deviatiiarov R., Gams A., Kulakovskiy I., Buyan A., Meshcheryakov G, Syunyaev R., Singh R., Shah P., Tatarinova T., Gusev O., Efimov I. An atlas of transcribed human cardiac promoters and enhancers reveals an important role of regulatory elements in heart failure. Nature Cardiovasc. Res.2023 2 1: 58-75. IF:14.6/CI:4 Makhnovskii PA, Gusev OA, Bokov RO, Gazizova GR, Vepkhvadze TF, Lysenko EA, Vinogradova OL, Kolpakov FA, Popov DV. Alternative transcription start sites contribute to acute-stress-induced transcriptome response in human skeletal muscle. Hum Genomics. 2022 Jul 22;16(1):24. IF:6.4/CI:4 Yoshida Y, Shaikhutdinov N, Kozlova O, Itoh M, Tagami M, Murata M, Nishiyori- Sueki H, Kojima-Ishiyama M, Noma S, Cherkasov A, Gazizova G, Nasibullina A, Deviatiiarov R, Shagimardanova E, Ryabova A, Yamaguchi K, Bino T, Shigenobu S, Tokumoto S, Miyata Y, Cornette R, Yamada TG, Funahashi A, Tomita M, Gusev O, Kikawada T. High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance. NAR Genom Bioinform. 2022 Apr 5;4(2):lqac029. IF:7.8/CI:3 Grapotte M, Saraswat M, Bessière C, Menichelli C, Ramilowski JA, Severin J, Hayashizaki Y, Itoh M, Tagami M, Murata M, Kojima-Ishiyama M, Noma S, Noguchi S, Kasukawa T, Hasegawa A, Suzuki H, Nishiyori-Sueki H, Frith MC; FANTOM consortium, Chatelain C, Carninci P, de Hoon MJL, Wasserman WW, Bréhélin L, Lecellier CH. Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nat Commun. 2022 Mar 1;13(1):1200. IF:17.6/CI:24 Deviatiiarov R, Ishikawa K, Gazizova G, Abe T, Kiyonari H, Takahashi M, Gusev O, Sunagawa GA. Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle. Commun Biol. 2021 Nov 15;4(1):1290. IF:6.58/CI:0 Bannasch DL, Kaelin CB, Letko A, Loechel R, Hug P, Jagannathan V, Henkel J, Roosje P, Hytönen MK, Lohi H, Arumilli M; DoGA consortium, Minor KM, Mickelson JR, Drögemüller C, Barsh GS, Leeb T. Dog colour patterns explained by modular promoters of ancient canid origin. Nat Ecol Evol. 2021 Oct;5(10):1415-1423. IF:19.1/CI:3 Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisén J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundström E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I. Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin. Nat Genet. 2021 May;53(5):694-706. IF:41.3/CI:28 Ryabova A, Cornette R, Cherkasov A, Watanabe M, Okuda T, Shagimardanova E, Kikawada T, Gusev O. Combined metabolome and transcriptome analysis reveals key components of complete desiccation tolerance in an anhydrobiotic insect. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19209-19220. doi: 10.1073/pnas.2003650117. Epub 2020 Jul 28. IF:12.7/CI:13 Nikitin AG, Chudakova DA, Enikeev RF, Sakaeva D, Druzhkov M, Shigapova LH, Brovkina OI, Shagimardanova EI, Gusev OA, Gordiev MG. Lynch Syndrome Germline Mutations in Breast Cancer: Next Generation Sequencing Case-Control Study of 1,263 Participants. Front Oncol. 2020 May 29;10:666. IF:5.7/CI:9 Yamada TG, Hiki Y, Hiroi NF, Shagimardanova E, Gusev O, Cornette R, Kikawada T, Funahashi A. Identification of a master transcription factor and a regulatory mechanism for desiccation tolerance in the anhydrobiotic cell line Pv11. PLoS One. 2020 Mar 19;15(3):e0230218. IF:3.7/CI:6 Makhnovskii PA, Zgoda VG, Bokov RO, Shagimardanova EI, Gazizova GR, Gusev OA, Lysenko EA, Kolpakov FA, Vinogradova OL, Popov DV. Regulation of Proteins in Human Skeletal Muscle: The Role of Transcription. Sci Rep. 2020 Feb 26;10(1):3514. IF:4.9/CI:9 |
| 取得資格（認定、専門医等） | |
| 科研費研究者番号 | 30711999 |
| 更新日 | 2023-08-28 |
| 研究業績 | 教育活動 | researchmap(JST) |