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業績


 

原著

 
  1. Ehata S, Hanyu A, Fujime M, Katsuno Y, Fukunaga E, Goto K, Ishikawa Y, Nomura K, Yokoo H, Shimizu T, Ogata E, Miyazono K, Shimizu K, Imamura T.
    Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.
    Cancer Sci. 2006 Nov 15
  2. Matsuda T, Fujime M, Suda K.
    Relationship between the prostatic tissue components and natural history of benign prostatic hyperplasia.
    Anal Quant Cytol Histol. 2006 Jun;28(3):121-4.
  3. Fujita K, Itoh Y, Wada R, Nagao K, Fujime M.
    Embryonal carcinoma producing DU-PAN-2 with burned-out phenomenon in the testis.
    Int J Urol. 2006 Apr;13(4):473-5.
  4. Shirai M, Yamanaka M, Shiina H, Igawa M, Kawakami T, Ishii N, Lue TF, Fujime M, Dahiya R.
    Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat. Biochem Biophys Res Commun. 2006 Mar 17;341(3):755-62. Epub 2006 Jan 19.
  5. Arai T, Fujita K, Fujime M, Irimura T.
    Expression of sialylated MUC1 in prostate cancer: relationship to clinical stage and prognosis. Int J Urol. 2005 Jul;12(7):654-61.
  6. Mehmut M, Takeda K, Abe M, Ogata H, Hirose S, Okumura K, Fujime M.
    Fas ligand and TNF-related apoptosis-inducing ligand induction on infiltrating lymphocytes in bladder carcinoma by bacillus Calmette-Guerin treatment. Urol Int. 2005;75(1):80-7.
  7. Ogishima T, Shiina H, Breault JE, Terashima M, Honda S, Enokida H, Urakami S, Tokizane T, Kawakami T, Ribeiro-Filho LA, Fujime M, Kane CJ, Carroll PR, Igawa M, Dahiya R.
    Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancer. Oncogene. 2005 Oct 13;24(45):6765-72.
  8. Matsumoto T, Fukunaga M, Fujii H, Arakawa A, Yamasaki S, Takase M, Kuwatsuru R, Ishii Y, Fujime M.
    Inguinal dedifferentiated liposarcoma with meningothelial-like whorls and metaplastic bone formation.
    Histopathology. 2005 May;46(5):594-6. No abstract available.
  9. Fujita K, Wada R, Sakurai T, Sashide K, Fujime M.
    Primary carcinoid tumor of the testis with teratoma metastatic to the para-aortic lymph node. Int J Urol. 2005 Mar;12(3):328-31.
  10. Yamashita R, Mashima E, Ogishima T, Wakumoto Y, Sakamoto Y, Fujime M.
    Primary signet ring cell carcinoma of the bladder: a case report Hinyokika Kiyo. 2005 Feb;51(2):117-9. Review. Japanese.
  11. Ogishima T, Shiina H, Breault JE, Tabatabai L, Bassett WW, Enokida H, Li LC, Kawakami T, Urakami S, Ribeiro-Filho LA, Terashima M, Fujime M, Igawa M, Dahiya R.
    Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer. Clin Cancer Res. 2005 Feb 1;11(3):1028-36.
  12. Yamanaka M, Shirai M, Shiina H, Tanaka Y, Enokida H, Tsujimura A, Matsumiya K, Okuyama A, Dahiya R.
    Vascular endothelial growth factor restores erectile function through inhibition of apoptosis in diabetic rat penile crura.
    J Urol. 2005 Jan;173(1):318-23.
  13. Hanazawa K, Higashi N, Kawachi Y, Suzuki F, Ishi K, Fujime M.
    Small cell carcinoma of the prostate with hypercalcemia. Int J Urol. 2005 Jan;12(1):108-10.
  14. Shirai M, Yamanaka M, Shiina H, Igawa M, Ogishima T, Fujime M, Ishii N, Okuyama A, Lue TF, Dahiya R.
    Androgen, estrogen, and progesterone receptor gene regulation during diabetic erectile dysfunction and insulin treatment. Urology. 2004 Dec;64(6):1244-9.
  15. Matsuda T, Abe H, Takase M, Arakawa A, Matsumoto T, Fujime M, Suda K.
    Case of combined adrenal cortical adenoma and myelolipoma. Pathol Int. 2004 Sep;54(9):725-9.
  16. Sashide K, Isobe H, Wakumoto Y, Hanazawa K, Fujita K, Fujime M.
    CA19-9 as a serum marker for poor prognosis in urothelial carcinoma.
    Urol Int. 2004;72(2):112-7.
  17. Shirai M, Yamanaka M, Shiina H, Igawa M, Fujime M, Lue TF, Dahiya R.
    Downregulation of androgen, estrogen and progesterone receptor genes and protein is involved in aging-related erectile dysfunction.
    Int J Impot Res. 2003 Dec;15(6):391-6.
  18. Yamanaka M, Shirai M, Shiina H, Tanaka Y, Tsujimura A, Matsumiya K, Okuyama A, Dahiya R.
    Diabetes induced erectile dysfunction and apoptosis in penile crura are recovered by insulin treatment in rats.
    J Urol. 2003 Jul;170(1):291-7.
  19. Shiina H, Igawa M, Breault J, Ribeiro-Filho L, Pookot D, Urakami S, Terashima M, Deguchi M, Yamanaka M, Shirai M, Kaneuchi M, Kane CJ, Dahiya R.
    The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma.
    Clin Cancer Res. 2003 Jun;9(6):2121-32.
  20. Yamanaka M, Shirai M, Shiina H, Shirai M, Tanaka Y, Fujime M, Okuyama A, Dahiya R. Loss of anti-apoptotic genes in aging rat crura.
    J Urol. 2002 Nov;168(5):2296-300.
  21. Hanazawa K, Tanaka M, Watanabe R, Fujime M.
    Interferon therapy for renal cell carcinoma in hemodialysis patients: report of two patients.
    Int J Urol. 2000 May;7(5):189-92.
  22. Isobe H, Takashima H, Higashi N, Murakami Y, Fujita K, Hanazawa K, Fujime M, Matsumoto T.
    Primary carcinoid tumor in a horseshoe kidney. Int J Urol. 2000 May;7(5):184-8. Review.
  23. Hanazawa K, Koizumi K, Tanaka M, Watanabe R, Fujime M.
    Total replacement of the aorta and the inferior vena cava after resection of an extra-adrenal malignant pheochromocytoma. Urol Int. 2000;64(2):108-10.
  24. Hanazawa K, Tanaka M, Watanabe R, Fujime M.
    Collection of peripheral blood stem cells with granulocyte-colony-stimulating factor alone in testicular cancer patients. Int J Urol. 2000 Mar;7(3):77-82.
  25. Fujita K, Denda K, Yamamoto M, Matsumoto T, Fujime M, Irimura T.
    Expression of MUC1 mucins inversely correlated with post-surgical survival of renal cell carcinoma patients. Br J Cancer. 1999 Apr;80(1-2):301-8.
  26. Morozumi M, Ogawa Y, Fujime M, Kitagawa R.
    Distal ureteral atresia associated with crossed renal ectopia with fusion: recovery of renal function after release of a 10-year ureteral obstruction. Int J Urol. 1997 Sep;4(5):512-5.
  27. Noto K, Fujime M, Isobe H, Wakumato Y, Kawachi Y.
    Determination of urinary CA19-9 levels in urothelial cancer--assessment of its role in diagnosis Nippon Hinyokika Gakkai Zasshi. 1997 Mar;88(3):406-13. Japanese. Erratum in: Nippon Hinyokika Gakkai Zasshi 1997 Apr;88(4):511.
  28. Honda S, Sakamoto Y, Fujime M, Kitagawa R.
    Immunohistochemical study of tumor-infiltrating lymphocytes before and after intravesical bacillus Calmette-Guerin treatment for superficial bladder cancer. Int J Urol. 1997 Jan;4(1):68-73.
  29. Fujita K, Sakamoto Y, Fujime M, Kitagawa R.
    Two cases of inflammatory skin metastasis from transitional cell carcinoma of the urinary bladder. Urol Int. 1994;53(2):114-6.
  30. Isobe H, Iwata S, Fujime M, Kitagawa R.
    Serum concentration of type IV collagen in urological cancer--comparison with serum concentration of laminin Nippon Hinyokika Gakkai Zasshi. 1993 Mar;84(3):457-62. Japanese.
  31. Kitagawa R, Fujime M, Sakamoto Y, Hanazawa K, Fujita K, Isobe H.
    Intralesional and transarterial administration of interferon for renal cell Carcinoma Gan To Kagaku Ryoho. 1992 Aug;19(10 Suppl):1462-5. Japanese.
  32. Fujita K, Yokota T, Oguri T, Fujime M, Kitagawa R.
    In vitro adherence of Staphylococcus saprophyticus, Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus aureus to human ureter. Urol Res. 1992;20(6):399-402.
  33. Kawachi Y, Fujime M, Kitagawa R.
    [Detubularized right-hemicolonic continent urinary reservoir with plicated terminal ileum]
    Nippon Hinyokika Gakkai Zasshi. 1990 Dec;81(12):1861-8. Japanese.
  34. Iwata S, Isobe H, Fujime M, Kitagawa R, Horikoshi S, Funabiki K, Koide H.
    Serum concentration of laminin in transitional cell carcinoma Nippon Hinyokika Gakkai Zasshi. 1990 Apr;81(4):518-23. Japanese.
  35. Fukushima T, Ouchi T, Sugiyama Y, Fujime M, Kitagawa R, Tanaka K, Hori N, Kondo Y, Kubota M, Ogawa H, et al.
    Clinical application of Sonolith 2000 type B on extracorporeal shock wave lithotripsy for upper urinary tract calculi Nippon Hinyokika Gakkai Zasshi. 1989 Sep;80(9):1294-301. Japanese.
  36. Iwata S, Isobe H, Fujime M, Kitagawa R, Horikoshi S, Funabiki K, Koide H.
    Serum concentration of laminin in renal cell carcinoma Nippon Hinyokika Gakkai Zasshi. 1989 Jun;80(6):870-4. Japanese.
  37. Morozumi M, Kawamura T, Fujime M, Uegane K, Kanemura M, Yoshida M, Tomita K.
    Urachal carcinoma accompanied with calcification: report of a case Hinyokika Kiyo. 1988 Sep;34(9):1657-60. Review. Japanese.
  38. Fujime M, Akaza H, Yoshida M, Kurooka Y, Taniguchi J, Kishi H, Umeda T, Isurugi K, Niijima T.
    Cerebellar metastasis from renal cell carcinoma Nippon Hinyokika Gakkai Zasshi. 1986 Jul;77(7):1164-8. Japanese. No abstract available.
   
 

学会発表

 
  1. VASCULAR ENDOTHELIAL GROWTH FACTOR RESTORES ERECTILE FUNCTION THROUGH MODULATION OF THE INSULIN-LIKE GROWTH FACTOR SYSTEM IN DIABETIC RAT PENILE CRURA
    Masato Shirai, Masaki Yamanaka, Hiroaki Shiina, Masao Deguchi, Edward J Yun, Mikio Igawa, Makoto Fujime, Tom F Lue, Rajvir Dahiya American Urological Association annual meeting at San Francisco 5/11/2004
  2. THE EFFECT OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN PENILE CRURA OF THE DIABETIC RAT: POSSIBLE ROLE OF THE ANDROGEN, ESTROGEN AND PROGESTERONE RECEPTORS
    Masato Shirai, Masaki Yamanaka, Hiroaki Shiina, Joseph A Mitchell, Masao Deguchi, Edward J Yun, Mikio Igawa, Makoto Fujime, Tom F Lue, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/29/2003
  3. ANDROGEN, ESTROGEN AND PROGESTERONE RECEPTOR GENES REGULATION DURING DIABETIC-ERECTILE DYSFUNCTION AND INSULIN TREATMENT
    Masato Shirai, Masaki Yamanaka, Hiroaki Shiina, Joseph A Mitchell, Masao Deguchi, Edward J Yun, Mikio Igawa, Makoto Fujime, Tom F Lue, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/29/2003
  4. INACTIVATION OF ANDROGEN, ESTROGEN AND PROGESTERONE RECEPTOR GENES AND PROTEIN ARE INVOLVED IN AGING-INDUCED ERECTILE DYSFUNCTION
    Masato Shirai, Masaki Yamanaka, Hiroaki Shiina, Joseph A Mitchell, Masao Deguchi, Edward J Yun, Mikio Igawa, Makoto Fujime, Tom F Lue, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/29/2003
  5. DIABETES-INDUCED ERECTILE DYSFUNCTION AND APOPTOSIS IN PENILE CAVERNOSUM ARE REVERSED BY INSULIN TREATMENT IN RATS
    Masaki Yamanaka, Masato Shirai, Hiroaki Shiina, Masao Deguchi, Joseph A Mitchell, Edward J Yun, Akira Tsujimura, Kiyomi Matsumiya, Akihiko Okuyama, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/29/2003
  6. VASCULAR ENDOTHELIAL GROWTH FACTOR RESTORES ERECTILE FUNCTION THROUGH AN INHIBITION OF APOPTOSIS IN DIABETIC RAT PENILE CRURA
    Masaki Yamanaka, Masato Shirai, Hiroaki Shiina, Masao Deguchi, Joseph A Mitchell, Edward J Yun, Akira Tsujimura, Kiyomi Matsumiya, Akihiko Okuyama, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/29/2003
  7. HIGH FREQUENCY OF SINGLE NUCLEOTIDE POLYMORPHISM ON EXON 23 OF HMSH3 GENE IN HUMAN RENAL CANCER
    Masao Deguchi, Hiroaki Shiina, Joseph A Mitchell, Edward J Yun, Masato Shirai, Masaki Yamanaka, Koichi Nakajima, Christopher J Kane, Mikio Igawa, Peter Carroll, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/29/2003
  8. POOR PROGNOSIS OF RENAL CELL CARCINOMA IS DUE TO HYPERMETHYLATION OF GAMMA-CATENIN GENE
    Hiroaki Shiina, Julia Breault, Deepa Pookot, Leopoldo A Ribeiro-Filho, Masato Shirai, Masao Deguchi, Masaki Yamanaka, Christopher J Kane, Mikio Igawa, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/27/2003
  9. HORMONE REFRACTORY PROSTATE CANCER HAS HIGH FREQUENCY OF GAMMA-CATENIN MUTATIONS THAT INHIBIT APOPTOSIS
    Hiroaki Shiina, Julia Breault, Deepa Pookot, Leopoldo A Ribeiro-Filho, Masato Shirai, Masao Deguchi, Masaki Yamanaka, Christopher J Kane, Mikio Igawa, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/27/2003
  10. VASCULAR ENDOTHELIAL GROWTH FACTOR CAN REGENERATE BLADDER ACELLULAR MATRIX GRAFT: HISTOLOGIC AND FUNCTIONAL EVALUATION
    Mohamed Youssif, Hiroaki Shiina, Masato Shirai, Curtis Gleason, Lora Nunes Nunes, Mikio Igawa, Rajvir Dahiya, Emil A Tanagho American Urological Association annual meeting at Chicago 4/27/2003
  11. REGENERATION OF THE BLADDER ACELLULAR MATRIX GRAFT IN A DIABETIC RAT MODEL
    Mohamed Youssif, Hiroaki Shiina, Masato Shirai, Curtis Gleason, Lora Nunes Nunes, Mikio Igawa, Rajvir Dahiya, Emil A Tanagho American Urological Association annual meeting at Chicago 4/27/2003
  12. GENETIC AND EPIGENETIC INACTIVATION OF GAMMA-CATENIN GENE IN INITIATION OF HUMAN PROSTATE CANCER
    Hiroaki Shiina, Julia Breault, Deepa Pookot, Leopoldo A Ribeiro-Filho, Masato Shirai, Masao Deguchi, Masaki Yamanaka, Christopher J Kane, Mikio Igawa, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Chicago 4/27/2003
  13. LOSS OF APOPTOTIC GENES IN AGING RAT CRURA
    Masaki Yamanaka, Masato Shirai, Hiroaki Shiina, Yuichiro Tanaka, Reza Z Goharderakhshan, Aditi Patra, Akihiko Okuyama, Makoto Fujime, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Orlando 5/28/2002
  14. HEPARANASE GENE EXPRESSION IS ASSOCIATED WITH HIGHER RISK OF EARLY METASTASIS IN RENAL CELL CARCINOMA
    Hiroaki Shiina, Masao Deguchi, Leopoldo A Ribeiro-Filho, Masato Shirai, Masaki Yamanaka, Reza Z Goharderakshan, Shinji Urakami, Hirofumi Kishi, Nobuhisa Ishii,   Mikio Igawa, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Orlando 5/27/2002
  15. DNA MISMATCH REPAIR GENES IN RENAL CELL CARCINOMA
    Masao Deguchi, Hiroaki Shiina, Leopoldo A Ribeiro-Filho, Masato Shirai, Masaki Yamanaka, Nobuhisa Ishii, Koichi Nakajima, Tatsuaki Yoneda, Mikio Igawa, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Orlando 5/27/2002
  16. CHROMOSOME 9P21-23 DELETIONS ARE INVOLVED IN HUMAN RENAL CELL CARCINOMA
    Joseph P Franks, Brian Grady, Reza Z Goharderakhshan, Leopoldo A Ribeiro-Filho, Masaki Yamanaka, Masato Shirai, Hiroaki Shiina, James Chang, Peter R Carroll, Rajvir Dahiya American Urological Association annual meeting at Orlando 5/27/2002
  17. VEGF restores erectile function through modulation of the sex hormone receptors in diabetic rat penis
    Masato Shirai 日本泌尿器科学会総会 大阪 4/10/2004
  18. 加齢に伴う勃起障害モデルを用いた、アンドロゲン、エストロゲン及びプロゲステロンレセプター発現の検討
    白井雅人、藤目真、他 日本泌尿器科学会西部総会 島根 11/15/2003
  19. 糖尿病性勃起障害モデルを用いた、アンドロゲン、エストロゲン及びプロゲステロンレセプター発現の検討
    白井雅人、藤目真、他 日本泌尿器科学会西部総会 島根 11/15/2003
 
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