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2010~20092008200720062005~2004

2009

Symposiums / Invited presentations

• Niyonsaba F, Ushio H, Nagaoka I, Ogawa H, Okumura K: The antimicrobial peptides human β-defensins mediate secretion of pruritogenic factors in human mast cells. Cytokine 48: 41, Tri-Society Annual Conference, Lisbon, Oct 2009
• Nagaoka I, Igarashi M, Hua J, Ju Y, Yomogida S, Sakamoto K: Recent aspects of the anti-inflammatory actions of glucosamine. The 11th International Conference on Chitin and Chitosan & The 8th Asia-Pacific Chitin and Chitosan Symposium, Program & Abstracts 11, Taipei, Sep 2009.
• Nagaoka I, Naito K, Watari T, Yoshimura M, Igarashi M, Sakamoto K, Tsuruta A, Yamamoto T, Ishida K, Yamaguchi H, Kaneko K: Evaluation of the effect of glucosamine administration on the biomarkers for cartilage metabolism. Chitin Chitosan Res 15, 84-85, 23th Chitin and Chitosan Symposium, Saga, Aug 2009 (Japanese)

Oral / Poster presentations

• Nagaoka I, Shibusawa K, Murakami T, Tamura H: Antimicrobial cathelicidin peptide CAP11 suppresses HMGB1 (high mobility group box-1) release from lipopolysaccharide-stimulated mononuclear phagocytes via the prevention of necrotic cell death. Cytokine 48: 97, Tri-Society Annual Conference, Lisbon, Oct 2009.
• Murakami T, Tamura H, Nagaoka I: Antimicrobial cathelicidin peptide CAP11 suppresses the production and release of septic mediators in endotoxin shock mice. Cytokine 48: 111, Tri-Society Annual Conference, Lisbon, Oct 2009.
• Igarashi M, Kaga I, Hua J, Takamori Y, Sakamoto K, Miyazawa K, Nagaoka I: Effect of amino monosaccharides and uronic acids on the expression of hyaluronan-synthesizing and -degrading enzymes in human synovial cells and chondrocytes. Seikagaku 81: 408, The 82nd Annual Meting of the Japanese Biochemical Society, Kobe, Oct 2009.
• Sugaya K, Igarashi M, Tsubata M, Nagaoka I: Effect of flavangenol and exercise on apoE knockout mice. Seikagaku 81: 328, The 82nd Annual Meting of the Japanese Biochemical Society, Kobe, Oct 2009.
• Suzuki K, Shibusawa K, Kuwahara K, Iba T, Yamakura F, Tamura T, Nagaoka I: Cathelicidin family of antimicrobial peptide LL-37 inhibits the LPS-induced apoptosis in endothelial cells. Seikagaku 81: 200, 396, The 82nd Annual Meting of the Japanese Biochemical Society, Kobe, Oct 2009.
• Hosoda H, Tamura H, Kida S, Nagaoka I: Regulation of the expression of TREM-1 gene in macrophages by LPS stimulation. Seikagaku 81: 194, 373, The 82nd Annual Meting of the Japanese Biochemical Society, Kobe, Oct 2009.
• Someya A, Moss J, Vaughan M, Nagaoka I: Role of ARF-GEP100 in LPS-stimulated macrophage phagocytosis. Seikagaku 81: 176, 373, The 82nd Annual Meting of the Japanese Biochemical Society, Kobe, Oct 2009.
• Nagaoka I, Yoshimura M, Igarashi M, Sakamoto K, Tsuruta A, Yamamoto T, Ishida K, Yamaguchi H: Effects of glucosamine administration on cartilage and bone biomarkers in soccer players. Seikagaku 81: 180, 408, The 82nd Annual Meting of the Japanese Biochemical Society, Kobe, Oct 2009.
• Igarashi M, Kaga I, Hua J, Takamori Y, Sakamoto K, Miyazawa K, Nagaoka I: The effects of glucosamine-derivatives and uronic acids on the production of glycosaminoglycans by human synovial cells and chondrocytes. The 11th International Conference on Chitin and Chitosan & The 8th Asia-Pacific Chitin and Chitosan Symposium, Program & Abstracts 95, Taipei, Sep 2009.
• Igarashi M, Kaga I, Hua J, Takamori Y, Sugaya K, Sakamoto K, Miyazawa K, Nagaoka I: Effect of glucosamine-derivatives and uronic acids on the productionof glycosaminoglycans by human synovial cells and chondrocytes. Chitin Chitosan Res 15, 118-119, 23th Chitin and Chitosan Symposium, Saga, Aug 2009 (Japanese)
• Murakami T, Tamura H, Nagaoka I: Antimicrobial cathelicidin peptide CAP11 suppresses the production and release of septic mediators in a D-galactosamine-sensitized endotoxin shock model. Inflamm Res Suppl 2: S152, The 9th World Conference on Inflammation, Tokyo, Jul 2009.
• Hosoda H, Tamura H, Nagaoka I: Regulation of TREM-1 expression in macrophages by LPS stimulation. Inflamm Res Suppl 2: S157, The 9th World Conference on Inflammation, Tokyo, Jul 2009.
• Igarashi M, Kaga I, Hua J, Takamori Y, Sakamoto K, Miyazawa K, Nagaoka I: Effect of amino monosaccharides (glucosamine-derivatives) and uronic acids on the production of glycosaminoglycans by human synovial cells and chondrocytes. Inflamm Res Suppl 2: S172, The 9th World Conference on Inflammation, Tokyo, Jul 2009.
• Naito K, Watari T, Furuhara A, Iwase H, Nagaoka I, Kaneko K: Low-intensity pulsed ultrasound enhances the synthesis of articular type II collagen in a rat osteoarthritis model The 22nd Annual Meeting of the Japanese Society of Cartilage Metabolism Program 109, The 22nd Annual Meeting of the Japanese Society of Cartilage Metabolism, Nagoya, Mar 2009.
• Watari T, Naito K, Sakamoto K, Nagaoka I, Kaneko K: Evaluation of the effect of glucosamine and chitosan on the cartilage metabolism in spontaneous knee osteoarthritis mice (STR/OrtCrjl). The 22nd Annual Meeting of the Japanese Society of Cartilage Metabolism Program 111, The 22nd Annual Meeting of the Japanese Society of Cartilage Metabolism, Nagoya, Mar 2009.
• Igarashi M, Kaga I, Hua J, Takamori Y, Sakamoto K, Miyazawa K, Nagaoka I: The effect of amino monosaccharides and uronic acids on glycosaminoglycan production by human synovial cells and chondrocytes. The 5th Glucosamine Research Academic Meeting Program, 18-19, The 5th Glucosamine Research Academic Meeting, Tokyo, Feb 2009.
• Nagaoka I, Yoshimura M, Sakamoto K, Tsuruta A, Yamamoto T, Ishida K, Yamaguchi H: Effect of glucosamine on the biomarkers for articular cartilage in soccer players. The 5th Glucosamine Research Academic Meeting Program, 20-21, The 5th Glucosamine Research Academic Meeting, Tokyo, Feb 2009.

2008

Oral / Poster presentations

• Watari T, Naito K, Nagaoka I, Yoshimura M, Ishijima M, Yamamoto T, Yamaguchi H, Tomonaga A, Kurosawa H, Kaneko K: Evaluation of knee osteoarthritis using type II collagen-specific degradation marker C2C and synthesis marker CPII. 13 éme Réunion de la Société Franco-Japonaise d’ Orthopédie. Tokyo, Sep 2008.
• Someya A, Moss J, Vaughan M, Nagaoka I: Role of ARF-GEP100 in phagocytosis of macrophages. BMB2007 Abstract: 217, Kobe, Dec 2008 (Japanese)
• Igarashi M, Kaga I, Takamori Y, Sakamoto K, Miyazawa K, Nagaoka I: The effect of amino monosaccharides and uronic acids on glycosaminoglycan production by human synovial cells and chondrocytes. BMB2008 Abstract: 315, Kobe, Dec 2008 (Japanese)
• Hosoda H, Tsutsumi-Ishii Y, Nagaoka I: Regulation mechanism for the mRNA expression of triggering receptor expressed on myeloid cells-1 (TREM-1) byLPS in macrophage/monocyte cells. BMB2007 Abstract: 381, Kobe, Dec 2008 (Japanese)
• Nagaoka I, Yomogida S, Igarashi M, Sugaya K, Sakamoto K: Effect of glucosamine on atherosclerosis using atherosclerotic B6/KOR/Apoeshl mice. BMB2008 Abstract: 492, Kobe, Dec 2008 (Japanese)
• Sugaya K, Igarasi M, Tsubata M, Nagaoka I: Flavangenol inhibits apolipoprotein B secretion by HepG2 cells. BMB2008 Abstract: 493, Kobe, Dec 2008 (Japanese)
• Shibusawa K, Murakami T, Tamura H, Nagaoka I: Regulation of HMGB1 release by antimicrobial peptide CAP11 in septic shock. MBM2008 Abstract: 822, Kobe, Dec 2008 (Japanese)
• Murakami T, Tamura H, Nagaoka I: Inhibitory effects of antimicrobial cathelicidin peptide CAP11 on the production and release of septic mediators in D-galactosamine primed endotoxin shock model. MBM2008 Abstract: 822, Kobe, Dec 2008 (Japanese)
• Murakami T, Obata T, Tamura H, Nagaoka I: Antimicrobial cathelicidin peptide CAP11 suppresses the increase of HMGB1 and inflammatory cytokine levels in an endotoxin shock model. The 10th Biennial Meeting of the International Endotoxin and Innate Immunity Society, Edinburgh, Aug 2008.
• Koga I, Igarashi M, Noguchi T, Kurozumi S, Takamori Y, Sakamoto K, Arifuku I, Miyazawa K, Nagaoka I: Effect of amino monosaccharide on hyaluronan production by human synovial cells. Chitin Chitosan Res 14: 120-121, 22th Chitin and Chitosan Symposium, Niigata, Aug 2008 (Japanese)

2007

Oral / Poster presentations

• Hosoda H, Someya A, Tsutsumi-Ishii Y, Nagaoka I: Induction mechanism for the mRNA expression of triggering receptor expressed on myeloid cells-1 (TREM-1) by LPS in RAW264.7 cells. BMB2007 Abstract: 253, Yokohama, Dec 2007 (Japanese)
• Ju Y, Hua J, Yomogida S, Sakamoto K, Nagaoka I: Regulation of endothelial cell activation by an aminosugar, glucosamine. BMB2007 Abstract: 558, Yokohama, Dec 2007 (Japanese)
• Someya A, Nakazato T, Moss J, Vaughan M, Nagaoka I: Involvement of ARF-GEP100 in phagocytosis of macrophages. BMB2007 Abstract: 590, Yokohama, Dec 2007 (Japanese)
• Yomogida S, Hua J, Sakamoto K, Nagaoka I: Effect of glucosamine on dextran sodium sulfate-induced rat colitis. BMB2007 Abstract: 700, Yokohama, Dec 2007 (Japanese)
• Nagaoka I, Niyonsaba F, Tsutsumi-Ishii Y, Tamura H, Hirata M: Regulationof neutrophil apoptosis by antimicrobial human β-defensins. BMB2007 Abstract: 856, Yokohama, Dec 2007 (Japanese)
• Okuda D, Murakami T, Tamura H, Nagaoka I: Argumentation of protective effects of CAP11-related peptides against endotoxin shock. BMB2007 Abstract: 856, Yokohama, Dec 2007 (Japanese)
• Murakami T, Okuda D, Yomogida S, Tamura H, Nagaoka I: Inhibitory effects of antimicrobial cathelicidin peptide CAP11 on the production and release of anandamide and HMGB1 in an endotoxin shock model. BMB2007 Abstract: 856, Yokohama, Dec 2007 (Japanese)
• Murakami T, Yomogida S, Shibusawa K, Okuda D, Tamura H, Nagaoka I: Evaluation of the effects of antimicrobial cathelicidin peptide CAP11 on the production and release of anandamide and HMGB1 in an endotoxin shock model. J Leukoc Biol Suppl: 27, 40th Annual Meeting of the Society for Leukocyte Biology, Massachusetts, Oct 2007.
• Ju Y, Hua J, Yomogida S, Sakamoto K, Nagaoka I: Effect of glucosamine on human endothelial cell functions. Chitin Chitosan Res 13: 134-135, 21th Chitin and Chitosan Symposium, Kobe, Jul 2007 (Japanese)

2006

Symposiums / Invited presentations

• Nagaoka I: Bactericidal and LPS-neutralizing activities of antimicrobial cathelicidin peptides, CAP18/LL-37 and CAP11. The 5th Glucan Workshop, Tokyo, Dec 2006.
• Nagaoka I, Hua J, Yomogida S, Tsutsumi-Ishii Y, Sakamoto K: Anti-inflammatory and anti-platelet actions of glucosamine. Books of Abstracts, 40-41, 10^th International Conference on Chitin and Chitosan/ 7^th International Conference of the European Chitin Society, Montpellier France, Sep 2006.

Oral / Poster presentations

• Murakami T, Okuda D, Yomogida S, Tamura H, Nagaoka I: Suppressive effects of antibacterial cathelicidin peptide CAP11 on the anandamide production from LPS-stimulated mononuclear phagocytes. J Leukoc Biol Suppl: 37, Joint conference of the Society for Leukocyte Biology 39^th Annual Meeting and International Endotoxin and Innate Immunity Society 9^th Biennial Meeting, San Antonio, Texas, Nov 2006.
• Nagaoka I, Tsutsumi-Ishii Y, Tamura H, Hirata M: Antimicrobial human beta-defensin-3 suppresses neutrophil apoptosis via the action on CCR6. J Leukoc Biol Suppl: 78, Joint conference of the Society for Leukocyte Biology 39^th Annual Meeting and International Endotoxin and Innate Immunity Society 9^th Biennial Meeting, San Antonio, Texas, Nov 2006.
• Ota A, Yonemoto H, Someya A, Nagaoka I, Kinoshita K, Olson D: Changes in matrix metalloproteinase (MMP)-2, membrane type 1-MMP (MT1-MMP) and tissue inhibtors of matrix metalloproteinase (TIMP)-1 in fetal membrane during premature rupture of membranes at term. The 2006 Society for Gynecologic Investigation Annual Scientific Meeting, Toronto Canada, Mar 2006.

2005

Oral / Poster presentations

• Nagaoka I, Tsutsumi-Ishii Y, Tamura H, Hirata M: Antibacterial cathelicidin peptide human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPRL1 and P2X₇. J Leukoc Biol Suppl: 56, Society for Leukocyte Biology 38^th Annual Meeding, Oxford, UK, Sep 2005.
• Tsutsumi-Ishii Y, Shimada K, Daida H, Toman R, Nagaoka I: Role of Chlamydial lipopolysaccharide in innate immune responses of mononuclear phagocytes. J Leukoc Biol Suppl: 48, Society for Leukocyte Biology 38^th Annual Meeding, Oxford, UK, Sep 2005.