2016~201520142013201220112010~2009

2015

Symposiums / Invited presentations

• Nagaoka I, Hu Z, Suzuki K, Tamura H: Potential effects of human antimicrobial peptide LL-37 on macrophage pyroptosis and sepsis. The 88th Annual Meeting of The Japanese Pharmacological Society, Program S1F-15-4, Nagoya, Mar 2015.

Oral / Poster presentations

• Ochiai T, Nishimura K, Watanabe T, Kitajima M, Nakatani A, Nagayasu K, Naito S, Sato T, Kishine K, Takeda M, Abe Y, Hara C, Nagaoka I: Impact of individualized chemotherapy for advanced colorectal cancer (CRC) based on collagen gel droplet-embedded drug sensitivity test (CD-DST) in clinical setting. 23nd United European Gastroenterology Week, Barcelona, Oct 24-28, 2015.
• Suzuki K, Murakami T, Moribayashi T, Nagaoka I: A novel mechanism for the human host defense peptide LL-37-Induced mast cell degranulation. 48Th Annual Meeting of the Society for Leukocyte Biology -Immunity in Health and Disease, Abstract book 17, Raleigh, Sep 2015.
• Murakami T, Hu Z, Suzuki K, Tamura H, Nagaoka I: Mechanism for the lipopolysaccharide-induced release of high mobility group nucleosome-binding domain-1 from murine macrophage like RAW264.7. 48Th Annual Meeting of the Society for Leukocyte Biology -Immunity in Health and Disease, Abstract book 85, Raleigh, Sep 2015.
• Hu Z, Suzuki K, Tamura H, Nagaoka I: NETs (neutrophil extracellular traps) induce IL-1β production by macrophages in the presence of lipopolysaccharide. 48Th Annual Meeting of the Society for Leukocyte Biology -Immunity in Health and Disease, Abstract book 115, Raleigh, Sep 2015.

2014

Symposiums / Invited presentations

• Suzuki K, Hu Z, Tamura H, Nagaoka I: Human host defense peptide LL-37 enhances the LPS uptake by endothelial cells without cell activation: a possible role in the LPS clearance. Joint Meeting of the Society for Leukocyte Biology and the Interntional Endotoxin and Innate Immunity Society, Abstract book S25, Salt Lake City, Oct 2014.

Oral / Poster presentations

• Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I: Antimicrobial peptide LL-37 inhibits pyroptosis of macrophages and protects sepsis in a murine model. Joint Meeting of the Society for Leukocyte Biology and the Interntional Endotoxin and Innate Immunity Society, Abstract book S57, Salt Lake City, Oct 2014.
• Ochiai T, Nishimura K, Watanabe T, Nakatani A, Yoshino K, Sato T, Kishine K, Murakami H, Myoujin M, Nagaoka I: Individualized chemotherapy for advanced colorectal cancer (CRC) based on collagen gel droplet-embeded drug sensitivity test (CD-DST) in clinical setting. 22^nd United European Gastroenterology Week, Final Program 286, P1538 Vienna, Oct 2014.
• Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I: The effects of antimicrobial peptide LL-37 on the pyroptosis of macrophages and a polymicrobial sepsis model. The 12th Japan-Korea International Symposium on Microbiology 2014, Program & Abstracts 58, Tokyo, Mar 2014.
• Suzuki K, Tamura H, Nagaoka I: Human antimicrobial peptide LL-37 enhances the LPS uptake without cell activation in endothelial cells. The 12th Japan-Korea International Symposium on Microbiology 2014, Program & Abstracts 59, Tokyo, Mar 2014.
• Murakami T, Tamura H, Nagaoka I: Characterization of release mechanism of HMGN1, an alarmin, from LPS-stimulated RAW264.7 cells. The 12th Japan-Korea International Symposium on Microbiology 2014, Program & Abstracts 64, Tokyo, Mar 2014.
• Hosoda H, Tamura H, Nagaoka I: Regulation of TREM-1 gene expression in LPS-stimulated human monocytes/macrophages. The 12th Japan-Korea International Symposium on Microbiology 2014, Program & Abstracts 65, Tokyo, Mar 2014.

2013

Symposiums / Invited presentations

• Nagaoka I, Igarashi M, Someya A, Sakamoto K: Current aspects of the chondroprotective and anti-inflammatory actions of a chitosan monomer glucosamine. Chitin Chitosan Res 19: 135, 10^th Asia Pacific Chitin & Chitosan Symposium/27^th Japanese Chitin and Chitosan Symposium, Yonago, Oct 2013.
• Suzuki K, Nagaoka I: Regulation of LPS signaling by host defense peptides. Jpn J Bacteriol 68: 90, The 86th annual meeting of Japanese Society for Bacteriology, Chiba, Mar, 2013.

Oral / Poster presentations

• Someya A, Sakamoto K, Nagaoka I: Glucosamine suppresses IL-8 expression through the O-N-acetylglucosamine modification of transcription factor Sp1 in synovial cells. Chitin Chitosan Res 19: 215, 10^th Asia Pacific Chitin & Chitosan Symposium/27^th Japanese Chitin and Chitosan Symposium, Yonago, Oct 2013.
• Igarashi M, Suzuki K, Someya A, Sakamoto K, Nagaoka I: Sirtuin 1 is a target gene of glucosamine in chondrocytes. Chitin Chitosan Res 19: 218, 10^th Asia Pacific Chitin & Chitosan Symposium/27^th Japanese Chitin and Chitosan Symposium, Yonago, Oct 2013.
• Nagaoka I, Hu Z, Murakami T, Suzuki K, Tamura H: Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism. Abstract 35, Mechanisms and Functions of Non-apoptotic Cell Death, The 2013 Cold Spring Harbor Asia Conference, Suzhou, Apr 2013.
• Hu Z, Murakami T, Suzuki K, Tamura T, Nagaoka I: Role of antimicrobial cathelicidin LL-37 in LPS/ATP-induced pyroptosis of macrophages. Jpn J Bacteriol 68: 182, The 86th annual meeting of Japanese Society for Bacteriology, Chiba, Mar, 2013.
• Hosoda H, Tamura H, Nagaoka I: Regulation of TREM-1 gene expression by LPS in human monocytes/macrophages. Jpn J Bacteriol 68: 202, The 86th annual meeting of Japanese Society for Bacteriology, Chiba, Mar, 2013.
• Murakami T, Tamura H, Nagaoka I: The mechanism for the release of HMGN1, alarmin, from LPS stimulated RAW264.7 cells. Jpn J Bacteriol 68: 210, The 86th annual meeting of Japanese Society for Bacteriology, Chiba, Mar, 2013.

2012

Symposiums / Invited presentations

• Niyonsaba F, Nagaoka I: Novel roles of host defense peptides in cutaneous biology. IEIIS2012 Program & Abstract: 27, The 12^th Biennial International Endotoxin & Innate Immunity Society Meeting, Tokyo, Oct 2012.
• Suzuki K, Tamura H, Kumazawa Y, Nagaoka I: Host defense peptide LL-37 modulates the uptake of LPS by endothelial cells. IEIIS2012 Program & Abstract: 107, The 12^th Biennial International Endotoxin & Innate Immunity Society Meeting, Tokyo, Oct 2012.

Oral / Poster presentations

• Nagaoka I, Itoh H, Kume A, Honda T, Watanabe K, Hukagawa H, Tomonaga A, Yamamoto T, Yamaguchi H: Evaluation of the effect of milk beverage containing glucosamine on the symptoms and cartilage metabolism in individuals with knee osteoarthritis Seikagaku 84 (11): 118, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Someya A, Sakamoto K, Nagaoka I: Effect of glucosamine on gene expression and O-N-acetylglucosamine modification in synovial cells. Seikagaku 84 (11): 119, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Igarashi M, Sawada Y, Iguchi Y, Sugiyama H, Kitagawa Y, Nagaoka I: Evaluation of the anti-inflammatory effect of Ajuga decumbens extract on arthritis in vitro. Seikagaku 84 (11): 119, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Suzuki K, Yamakura F, Nagaoka I: Effect of antimicrobial peptide LL-37 on the LPS uptake by endothelial cells. Seikagaku 84 (11): 170, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I: Effect of antimicrobial peptide LL-37 on the LPS/ATP-induced pyroptosis of macrophages. Seikagaku 84 (11): 170, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Hosoda H, Tamura H, Nagaoka I: Regulation of the expression of TREM-1 gene in human monocytes/macrophages. Seikagaku 84 (11): 170, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Murakami T, Tamura H, Nagaoka I: The mechanism for the release of HMGN1, an alarmin, from LPS-stimulated macrophage-like cells. Seikagaku 84 (11): 170, The 85th Annual Meting of the Japanese Biochemical Society, Fukuoka, Dec 2012.
• Hosoda H, Tamura H, Nagaoka I: Regulation of the expression of TREM-1 by LPS in human monocytes/macrophages. IEIIS2012 Program & Abstract: 156, The 12^th Biennial International Endotoxin & Innate Immunity Society Meeting, Tokyo, Oct 2012.
• Murakami T, Tamura H, Nagaoka I: Evaluation of the mechanism for the release of HMGN1, an alarmin, from LPS stimulated RAW264.7 cells. IEIIS2012 Program & Abstract: 160, The 12^th Biennial International Endotoxin & Innate Immunity Society Meeting, Tokyo, Oct 2012.
• Hu Z, Murakami T, Suzuki K, Nagaoka I: Modulation of the LPS/ATP-induced pyroptosis of macrophages by antimicrobial cathelicidin peptide LL-37. IEIIS2012 Program & Abstract: 174, The 12^th Biennial International Endotoxin & Innate Immunity Society Meeting, Tokyo, Oct 2012.
• Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I: Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages. KJISM27, The 11th Korea-Japan International Symposium on Microbiology (XI-KJISM), Buyeo, Sep 2012.
• Suzuki K, Murakami T, Tamura H, Nagaoka I: An antimicrobial cathelicidin peptide LL-37 suppresses the LPS-induced endothelial cell apoptosis in vitro and in vivo. KJISM26, The 11th Korea-Japan International Symposium on Microbiology (XI-KJISM), Buyeo, Sep 2012.
• Someya A, Igarashi M, Sakamoto K, Nagaoka I: Comprehensive analysis of the effect of glucosamine on gene expression and O-N-acetylglucosamine modification in synovial cells. Chitin Chitosan Res 18, 178, 26th Chitin and Chitosan Symposium, Sapporo, Jul 2012 (Japanese)
• Suzuki K, Yamakura F, Tamura H, Nagaoka I: Antimicrobial peptide LL-37 enhances the uptake of LPS in liver sinusoidal endothelial cells. Japanese Journal of Bacteriology 67: 133, 85th annual meeting of Japanese Society for Bacteriology, Nagasaki, Mar 2012.
• Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I: Antimicrobial peptide LL-37 inhibits LPS/ATP-induced IL-1 release but not cell death of J774 cells. Japanese Journal of Bacteriology 67: 134, 85th annual meeting of Japanese Society for Bacteriology, Nagasaki, Mar 2012.
• Hosoda H, Tamura H, Nagaoka I: Regulation of TREM-1 gene expression in human mononuclear phagocytes. Japanese Journal of Bacteriology 67: 153, 85th annual meeting of Japanese Society for Bacteriology, Nagasaki, Mar 2012.
• Murakami T, Tamura H, Nagaoka I: Evaluation of the mechanism for the release of HMGN1, an alarmin, from LPS stimulated RAW264.7 cells. Japanese Journal of Bacteriology 67: 156, 85th annual meeting of Japanese Society for Bacteriology, Nagasaki, Mar 2012.

2011

Symposiums / Invited presentations

• Ishijima M, Kurosawa H, Ikeda H, Nagaoka I, Kaneko K: Biomarkers in osteoarthritis. OARSI and JSCM co-sponsored symposium. The 24th Annual Meeting of the Japanese Society of Cartilage Metabolism Program 60, Fukuoka, Mar 2011.
• Nagaoka I, Igarashi M, Hua J, Yomogida S, Sakamoto K: Anti-platelet and anti-atherosclerotic actions of glucosamine. The 7th Glucosamine Research Academic Meeting Program, 16, The 7th Glucosamine Research Academic Meeting, Tokyo, Jan 2011.

Oral / Poster presentations

• Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M: Antimicrobial peptides, human defensins and LL-37, modulate neutrophil apoptosis. International Union of Microbiological Societies 2011 Congress (IUMS2011), Program 131, Sapporo, Sep 2011.
• Suzuki K, Murakami T, Tamura H, Nagaoka I: An antimicrobial cathelicidin peptide LL-37 suppresses the LPS-induced endothelial cell apoptosis in vitro and in vivo. International Union of Microbiological Societies 2011 Congress (IUMS2011), Program 183, Sapporo, Sep 2011.
• Igarashi M, Sekiguchi Y, Okuno M, Nagaoka I: Effect of S-adenosylmethionine-containing food on the production of hyaluronic acid. Chitin Chitosan Res 17, 242, 25th Chitin and Chitosan Symposium, Nara, Sep 2011 (Japanese)
• Yamagishi Y, Igarashi M, Hirano S, Suguro S, Nagaoka I: Effects of sulfur amino acids and glucosamine on adjuvant arthritis in rats. Chitin Chitosan Res 17, 246, 25th Chitin and Chitosan Symposium, Nara, Sep 2011 (Japanese)
• Nagaoka I, Sugaya K, Igarashi M, Kojima Y: Evaluation of the effect of flavangenol on serum lipid peroxide level and development of atherosclerosis in spontaneously hyperlipidemic B6.KOR-Apoe^shl mice. Program & Abstracts 38, Inaugural International Academy of Sportology, Tokyo, Mar 2011.
• Igarashi M, Saiki A, Sakamoto K, Nagaoka I: Effect of glucosamine derivatives on osteoblastic cells. The 7th Glucosamine Research Academic Meeting Program, 6, The 7th Glucosamine Research Academic Meeting, Tokyo, Jan 2011.
• Momomura R, Naito K, Watari T, Homma Y, Iwase H, Ohike S, Terakado A, Nagaoka I, Kaneko K: Evaluation of the effect of glucosamine on Keirin athletes. The 7th Glucosamine Research Academic Meeting Program, 20, The 7th Glucosamine Research Academic Meeting, Tokyo, Jan 2011.
• Kanzaki N, Saito K, Maeda S, Kitagawa Y, Kiso Y, Yoshimura K, Yamamoto T, Watanabe K, Tomonaga A, Yamaguchi H, Nagaoka I: Effect of glucosamine hydrochloride, chondroitin sulfate, and quercetin glycosidecontaining diet on symptom and cartilage metabolism in subjects with knee pain. The 7th Glucosamine Research Academic Meeting Program, 22, The 7th Glucosamine Research Academic Meeting, Tokyo, Jan 2011.
• Nagaoka I, Nakasone Y, Watanabe K, Yamamoto T, Watanabe K, Tomonaga A, Yamaguchi H: Effect of a dietary supplement containing glucosamine produced from plants on symptoms and cartilage biomarkers in individuals with knee pain. The 7th Glucosamine Research Academic Meeting Program, 24, The 7th Glucosamine Research Academic Meeting, Tokyo, Jan 2011.
• Igarashi M, Sakamoto K, Nagaoka I: Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation. The 9th Asia-Pacific Chitin and Chitosan Symposium (APCC2011), Program and Abstract 70, Nha Trang, Aug 2011.

2010

Symposiums / Invited presentations

• Nagaoka I, Igarashi M, Hua J, Yomogida S, Ju Y, Sakamoto K: Biological activities of glucosamine and its related substances. Chitin Chitosan Res 16, 108-109, 24th Chitin and Chitosan Symposium, Tokyo, Jul 2010 (Japanese)

Oral / Poster presentations

• Sugaya K, Igarashi M, Tsubata M, Nagaoka I: Effect of flavangenol and spontaneous hyperlipidemic mice. BMB2010, 1P-1089, Kobe, Dec 2010.
• Igarashi M, Saiki A, Sakamoto K, Nagaoka I: Effect of glucosamine on osteoblastic differentiation makers. BMB2010, 1P-1123, Kobe, Dec 2010.
• Suzuki K, Murakami T, Tamura H, Nagaoka I: Cathelicidin family of antimicrobial peptide LL-37 suppresses the endothelial cell apoptosis in liver of D-galactosamine-sensitized endotoxin shock mice. BMB2010, 2P-1039, Kobe, Dec 2010.
• Nagaoka I, Suzuki K, Murakami T, Hosoda H, Tamura H: Alpha-defensins human neutrophil peptides suppress neutrophil apoptosis. BMB2010, 2P-1040, Kobe, Dec 2010.
• Murakami T, Tamura H, Nagaoka I: The effect of resolvin D1 on septic mediators of D-galactosamine primed endotoxin shock model. BMB2010, 2P-1045, Kobe, Dec 2010.
• Someya A, Moss J, Nagaoka I: ARF-GEP100, a guanine nucleotide-exchange protein for ADP-ribosylation factor, regulates phagocytosis of macrophages in an ARF6-dependent process. BMB20, 104T8-4(4P-0462), Kobe, Dec 2010.
• Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M: Evaluation of the effect of alpha-defensins human neutrophil peptides on neutrophil apoptosis. The three Rs of immunity: recognition, response and resolution. 63, Annual Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society, Vancouver, Oct 2010.
• Suzuki K, Murakami T, Tamura H, Nagaoka I: An antimicrobial cathelicidin peptide LL-37 suppresses the LPS-induced endothelial cell apoptosis. The three Rs of immunity: recognition, response and resolution. 109, Annual Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society, Vancouver, Oct 2010.
• Murakami T, Suzuki K, Tamura H, Nagaoka I: The effect of resolvin D1 on D-galactosamine-primed endotoxin shock model in mice. The three Rs of immunity: recognition, response and resolution. 213, Annual Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society, Vancouver, Oct 2010.
• Igarashi M, Sakamoto K, Nagaoka I: Effect of glucosamine on osteoblastic cells. Chitin Chitosan Res 16, 160-161, 24th Chitin and Chitosan Symposium, Tokyo, Jul 2010 (Japanese)
• Hosoda H, Tamura H, Nagaoka I: Regulation of TREM-1 gene expression in mononuclear phagocytes. Jap J Bacteriol 65: 105, The 83rd Annual Meeting of Japanese Society for Bacteriology, Yokohama, Mar 2010.
• Murakami T, Tamura T, Nagaoka I: The effect of resolvin D1 on D-galactosamine-primed endotoxin shock model in mice. Jap J Bacteriol 65: 187, The 83rd Annual Meeting of Japanese Society for Bacteriology, Yokohama, Mar 2010.
• Suzuki K, Kuwahara K, Iba T, Yamakura F, Tamura H, Nagaoka I: Inhibitory effect of antimicrobial peptide LL-37 on the LPS-induced endothelial cell apoptosis. Jap J Bacteriol 65: 181, The 83th Annual Meeting of Japanese Society for Bacteriology, Yokohama, Mar 2010.