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Mamoru IGARASHI, Ph. D.
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  • B. Sc. : School of Science and Engineering, Waseda University, Japan (1991)
  • M. Sc. : Graduate School of Science and Engineering, Waseda University, Japan (1993)
  • Ph. D. (Science): Waseda University, Japan

Current Research Projects

  1. Evaluation of the effect of glucosamine
  2. Nuclear receptors and bone metabolism


  • Igarashi M, Sakamoto K, Nagaoka I: Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation. Int J Mol Med 28: 373-379, 2011.
  • Igarashi M, Kaga I, Takamori Y, Sakamoto K, Miyazawa K, Nagaoka I: Effects of glucosamine-derivatives and uronic acids on the production of glycosaminoglycans by human synovial cells and chondrocytes. Int J Mol Med 27: 821-827, 2011.
  • Igarashi M, Yogiashi Y, Mihara M, Takada I, Kitagawa H, Kato S: Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene. Mol Cell Biol, 27: 7947-7954, 2007.
  • Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, Youn M-Y, Takeyama K, Nakamura T, Mezaki Y, Takezawa S, Yogiashi Y, Kitagawa H, Yamada G, Takada S, Minami Y, Shibuya H, Matsumoto K, Kato S: A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation. Nat Cell Biol, 9: 1273-1285, 2007.
  • Memezawa A, Takada I, Takeyama K, Igarashi M, Ito S, Aiba S, Kato S, Kouzmenko AP: Id2 gene-targeted crosstalk between Wnt and retinoid signaling regulates proliferation in human keratinocytes. Oncogene, 26: 5038-5045, 2007.