Kohsaka S, Nagano M, Ueno T, Suehara Y, Hayashi T, Shimada N, Takahashi K, Suzuki K, Takamochi K, Takahashi F, Mano H.
A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer.
Sci Transl Med. 2017 Nov 15;9(416).
Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, Giannakis M, Hahn WC, Cherniack AD, Meyerson M.
Somatic super-enhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor.
Cancer Discov. 2017 Sep 29. pii: CD-17-0532.
Hida T, Nokihara H, Kondo M, Kim YH, Azuma K, Seto T, Takiguchi Y, Nishio M, Yoshioka H, Imamura F, Hotta K, Watanabe S, Goto K, Satouchi M, Kozuki T, Shukuya T, Nakagawa K, Mitsudomi T, Yamamoto N, Asakawa T, Asabe R, Tanaka T, Tamura T.
Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.
Lancet. 2017 Jul 1;390(10089):29-39.
Okamoto S, Togo S, Nagata I, Shimizu K, Koinuma Y, Namba Y, Ito J, Uekusa T, Takahashi K. Lung adenocarcinoma expressing receptor for advanced glycation end-products with primary systemic AL amyloidosis: a case report and literature review. BMC Cancer. 17(1):22. doi: 10.1186/s12885-016-3009-3, 2017 Jan 3.265
Namba Y, Togo S, Tulafu M, Kadoya K, Nagahama KY, Taka H, Kaga N, Orimo A, Liu XD, Takahashi K. Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes. Respiratory Research. 18(1):46, 2017 Mar 11
Ishimori A, Harada N, Chiba A, Harada S, Matsuno K, Makino F, Ito J, Ohta S, Ono J, Atsuta R, Izuhara K, Takahashi K, Miyake S. Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma. Allergol Int. 66(2): 302-309, 2017 Apr 2.355
Nishino K, Yoshimi K, Shibuya T, Hayashi T, Mitani K, Kobayashi E, Ichikawa M, Asao T, Suzuki Y, Sato T, Shiota S, Kodama Y, Takahashi K, Seyama K. Protein-losing Enteropathy Caused by Intestinal or Colonic Lymphangiectasia Complicated by Sporadic Lymphangioleiomyomatosis: A Report of Two Cases.Intern Med. 56(8):943-948, 2017 Apr 15.
Arano N, Morio Y, Futagawa T, Hashizume A, Nagashima O, Sasaki SI, Tominaga S, Takahashi K. Lung metastases from cutaneous adenoid cystic carcinoma 23 years after initial treatment. Respir Med Case Rep. 21:121-123, 2017 Apr 19
Yamada T, Amann JM, Tanimoto A, Taniguchi H, Shukuya T, Timmers C, Yano S, Shilo K, Carbone DP.
Histone deacetylase inhibition enhances the antitumor activity of a MEK inhibitor in lung cancer cells harboring RAS mutations.
Mol Cancer Ther. 2017 Oct 27. pii: molcanther.0146.2017.
Shukuya T, Patel S, Shane-Carson K, He K, Bertino EM, Shilo K, Otterson GA, Carbone DP.
Lung Cancer Patients with Germline Mutations Detected by Next-Generation Sequencing and/or Liquid Biopsy.
J Thorac Oncol. 2017 Oct 5. pii: S1556-0864(17)32764-8.
Otsubo K, Nosaki K, Imamura CK, Ogata H, Fujita A, Sakata S, Hirai F, Toyokawa G, Iwama E, Harada T, Seto T, Takenoyama M, Ozeki T, Mushiroda T, Inada M, Kishimoto J, Tsuchihashi K, Suina K, Nagano O, Saya H, Nakanishi Y, Okamoto I.
Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non-small-cell lung cancer.
Cancer Sci. 2017 Sep;108(9):1843-1849.
Ohta T, Mita M, Hishinuma S, Ishii-Nozawa R, Takahashi K, Shoji M. Inhibition of ectopic arginine vasopressin production by phenytoin in the small cell lung cancer cell line Lu-165. Original Research. 2017 April 28. doi: 10.3389/fendo.2017.00094
Ai T, Yuri M, Tabe Y, Kakimoto A, Morishita S, Tsuchiya K, Takamochi K, Kodama Y, Takahashi F, Shigeki M, Horii T, Suzuki K, Takahashi K, Miida T, Ohsaka A. Comparison of the Analytical Performance Between cobas EGFR Assay and PCR-Clamp Method in the Detection of EGFR Mutations in Japanese Non-Small Cell Lung Cancer Patients. Clin Lab. 63(5):1021-1026, 2017 May 1
Nakamura K, Kato M, Shukuya T, Mori K, Sekimoto Y, Ihara H, Kanemaru R, Ko R, Shibayama R, Tajima K, Koyama R, Shimada N, Nagashima O, Takahashi F, Sasaki S, Takahashi K. Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study.BMC Cancer. 17(1):302.doi: 10.1186/s12885-017-3285-6. 2017 May 2
Togo S, Katagiri N, Namba Y, Tulafu M, Nagahama K, Kadoya K, Takamochi K, Oh S, Suzuki K, Sakurai F, Mizuguchi H, Urata Y, Takahashi K. Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients. Oncotarget. 8(21):34884-34895, 2017 May 23
Okamoto S, Komura M, Terao Y, Kurisaki-Arakawa A, Hayashi T, Saito T, Togo S, Shiokawa A, Mitani K, Kobayashi E, Kumasaka T, Takahashi K, Seyama K. Pneumothorax caused by cystic and nodular lung metastases from a malignant uterine perivascular epithelioid cell tumor (PEComa).Respir Med Case Rep. 22:77-82, 2017 Jun 27
Asao T, Fujiwara Y, Itahashi K, Kitahara S, Goto Y, Horinouchi H, Kanda S, Nokihara H, Yamamoto N, Takahashi K, Ohe Y. Sequential Use of Anaplastic Lymphoma Kinase Inhibitors in Japanese Patients With ALK-Rearranged Non-Small-Cell Lung Cancer: A Retrospective Analysis. Clin Lung Cancer. 18(4): e251-e258, 2017 Jul 3.030
Takaeshige T, Harada N, Sekimoto Y, Kanemaru R, Tsutsumi T, Matsuno K, Shiota S, Masuda A, Gotoh A, Asahina M, Uekusa T, Takahashi K. Pulmonary Intravascular large B-cell lymphoma(IVLBCL) disguised as an Asthma exacerbation in a patient with asthma. Intern Med. 56: 1885-1891, 2017
Kodama Y, Kishimoto Y, Muramatsu Y, Tatebe J, Yamamoto Y, Hirota N, Itoigawa Y, Atsuta R, Koike K, Sato T, Aizawa K, Takahashi K, Morita T, Homma S, Seyama K, Ishigami A. Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome, and bronchial asthma. Clin Respir J. 2015 Dec 14. doi: 10.1111/crj.12436. [Epub ahead of print] 1.512
Nurwidya F, Takahashi F, Kato M, Baskoro H, Hidayat M, Wirawan A, Takahashi K. CD44 silencing decreases the expression of stem cell-related factors induced by transforming growth factor β1 and tumor necrosis factor α in lung cancer: Preliminary findings. Bosn J Basic Med Sci. 2017 Apr 24. doi: 10.17305/bjbms.2017.1966. [Epub ahead of print]
Sandhu Y, Ando K, Takekawa H, Takagi H, Hirama M, Kido K, Takahashi K.
Safety of Bronchoscopy for Patients Undergoing Hemodialysis.
Respir Investig. 2017 Mar;55(2):173-175.
Yoshikawa H, Fujii M, Iwakami SI, Takeda I, Hayakawa D, Takahashi K.
Chylothorax ascribed to chronic heart failure in a woman of very advanced years.
Geriatr Gerontol Int. 2017 Jul;17(7):1133-1135.
Suzuki Y, Sato T, Sugimoto M, Baskoro H, Karasutani K, Mitsui A, Nurwidya F, Arano N, Kodama Y, Hirano SI, Ishigami A, Seyama K, Takahashi K.
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
Biochem Biophys Res Commun. 2017 Oct 7;492(1):74-81.
Honma Y, Togo S, Shimizu K, Tulafu M, Hayashi T, Uekusa T, Tominaga S, Kido K, Fujimoto Y, Nanba Y, Takamochi K, Oh S, Suzuki K, Takahashi K.
Expression of thymidylate synthase predicts clinical outcomes of S-1-based chemotherapy in squamous cell lung cancer.
Oncol Lett. 2017 Sep;14(3):3319-3326.
Jotatsu T, Yagishita S, Tajima K, Takahashi F, Mogushi K, Hidayat M, Wirawan A, Ko R, Kanemaru R, Shimada N, Mitani K, Saito T, Takamochi K, Suzuki K, Kohsaka S, Kojima S, Mukae H, Yatera K, Takahashi K.
LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.
Biochem Biophys Rep. 2016 Dec 1;9:86-94.
Ebana H, Mizobuchi T, Kurihara M, Kobayashi E, Haga T, Okamoto S, Takahashi K, Seyama K.
Novel clinical scoring system to identify patients with pneumothorax with suspicion for Birt-Hogg-Dubé syndrome.
Respirology. 2017 Sep 27. doi: 10.1111/resp.13191. [Epub ahead of print]
Ebana H, Hayashi T, Mitani K, Kobayashi E, Kumasaka T, Mizobuchi T, Kurihara M, Takahashi F, Takahashi K, Seyama K.
Oxidized regenerated cellulose induces pleural thickening in patients with pneumothorax: possible involvement of the mesothelial-mesenchymal transition.
Surg Today. 2017 Oct 12. doi: 10.1007/s00595-017-1597-4. [Epub ahead of print]
Nakamura K, Kato M, Miyashita Y, Nagashima O, Sasaki S, Tominaga S, Takahashi K.
Development of interstitial pneumonia during treatment with eribulin: a case report.
BMC Res Notes. 2017 Nov 6;10(1):557.
Tobino K, Hirai T, Johkoh T, Fujimoto K, Kawaguchi A, Tomiyama N, Takahashi K, Seyama K.
Difference of the progression of pulmonary cysts assessed by computed tomography among COPD, lymphangioleiomyomatosis, and Birt-Hogg-Dubé syndrome.
PLoS One. 2017 Dec 8;12(12):e0188771.
Takamochi K, Takahashi F, Suehara Y, Kitano S, Sato E, Kohsaka S, Hayashi T, Mano H, Suzuki K.
DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel Lung Cancer.
Lung Cancer 110:26-31. (2017)
Iwabuchi C, Ebana H, Ishiko A, Negishi A, Mizobuchi T, Kumasaka T, Kurihara M, Seyama K.
Skin lesions of Birt-Hogg-Dubé syndrome: Clinical and histopathological findings in 31 Japanese patients who presented with pneumothorax and/or multiple lung cysts.
J Dermatol Sci. 2017 Nov 2. pii: S0923-1811(17)30462-0.
Gupta N, Finlay GA, Kotloff RM, Strange C, Wilson KC, Young LR, Taveira-DaSilva AM, Johnson SR, Cottin V, Sahn SA, Ryu JH, Seyama K, Inoue Y, Downey GP, Han MK, Colby TV, Wikenheiser-Brokamp KA, Meyer CA, Smith K, Moss J, McCormack FX; ATS Assembly on Clinical Problems.
Lymphangioleiomyomatosis Diagnosis and Management: High-Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guideline.
Am J Respir Crit Care Med. 2017 Nov 15;196(10):1337-1348.
Kitamura N, Seyama K, Inoue Y, Nagai K, Suzuki M, Moriyama H, Takada T, Tazawa R, Hirai T, Mishima M, Hayashida M, Hirose M, Arai T, Sugimoto C, Hattori N, Watanabe K, Tamada T, Akazawa K, Tanaka T, Nakata K.
Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator-initiated prospective study.
Pharmacoepidemiol Drug Saf. 2017 Oct;26(10):1182-1189.
Onodera K, Sugiura H, Yamada M, Koarai A, Fujino N, Yanagisawa S, Tanaka R, Numakura T, Togo S, Sato K, Kyogoku Y, Hashimoto Y, Okazaki T, Tamada T, Kobayashi S, Yanai M, Miura M, Hoshikawa Y, Okada Y, Suzuki S, Ichinose M.
Decrease in an anti-ageing factor, growth differentiation factor 11, in chronic obstructive pulmonary disease.
Thorax. 2017 Oct;72(10):893-904.
Saito M, Fujiwara Y, Asao T, Honda T, Shimada Y, Kanai Y, Tsuta K, Kono K, Watanabe S, Ohe Y, Kohno T.
The genomic and epigenomic landscape in thymic carcinoma.
Carcinogenesis. 2017 Oct 26;38(11):1084-1091.
Konagai A, Yoshimura K, Hazama S, Yamamoto N, Aoki K, Ueno T, Fujioka M, Iijima H, Kato M, Uchida M, Wada T, Inoue M, Asao T, Fuse M, Wada S, Kuramasu A, Kamei R, Takeda S, Yamamoto S, Yoshino S, Oka M, Nagano H.
Correlation Between NKG2DL Expression and Antitumor Effect of Protein-bound Polysaccharide-K in Tumor-bearing Mouse Models.
Anticancer Res. 2017 Aug;37(8):4093-4101.
Nakamichi S, Horinouchi H, Asao T, Goto Y, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Ito Y, Watanabe SI, Ohe Y.
Comparison of Radiotherapy and Chemoradiotherapy for Locoregional Recurrence of Non-small-cell Lung Cancer Developing After Surgery.
Clin Lung Cancer. 2017 Nov;18(6):e441-e448.
Okuma HS, Horinouchi H, Kitahara S, Asao T, Sunami K, Goto Y, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Ohe Y.
Comparison of Amrubicin and Weekly Cisplatin/Etoposide/Irinotecan in Patients With Relapsed Small-cell Lung Cancer.
Clin Lung Cancer. 2017 Mar;18(2):234-240.
Shitara K, Doi T, Nagano O, Fukutani M, Hasegawa H, Nomura S, Sato A, Kuwata T, Asai K, Einaga Y, Tsuchihashi K, Suina K, Maeda Y, Saya H, Ohtsu A.
Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407).
Gastric Cancer. 2017 Nov;20(6):1004-1009.
Ikari J, Nelson AJ, Obaid J, Giron-Martinez A, Ikari K, Makino F, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Demeo D, Feghali-Bostwick C, Holz O, Rabe K, Liu X, Rennard SI.
Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease.
PLoS One. 2017 Sep 7;12(9):e0184039.
