2019年

  • Tsutsumi T, Nagaoka T, Yoshida T, Wang L, Kuriyama S, Suzuki Y, Nagata Y, Harada N, Kodama Y, Takahashi F, Morio Y, Takahashi K. Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation. PLoS one 24;14(7):e0214697. eCollection 2019.
  • Kadoya K, Togo S, Tulafu M, Namba Y, Iwai M, Watanabe J, Okabe T, Jin J, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Takeda T, Kondo N, Takahashi K. Specific features of fibrotic lung fibroblasts highly sensitive to fibrotic processes mediated via TGF-β-ERK5 interaction. Cell Physiol Biochem. 52(4):822-837, 2019 Jun 
  • Tajima K, Matsuda S, Yae T, Drapkin BJ, Morris R, Boukhali M, Niederhoffer K, Comaills V, Dubash T, Nieman L, Guo H, Magnus NKC, Dyson N, Shioda T, Haas W, Haber DA, Maheswaran S. SETD1A protects from senescence through regulation of the mitotic gene expression program. Nat Commun. 2019 Jun 28;10(1):2854.
  • Shukuya T, Yamada T, Koenig MJ, Xu J, Okimoto T, Li F, Amann JM, Carbone DP. The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer. J Thorac Oncol. 2019 Jun;14(6):1061-1076. Epub 2019
  • Kitajima S, Ivanova E, Guo S, Yoshida R, Campisi M, Sundararaman SK, Tange S, Mitsuishi Y, Thai TC, Masuda S, Piel BP, Sholl LM, Kirschmeier PT, Paweletz CP, Watanabe H, Yajima M, Barbie DA. Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer. Cancer Discov. 2019 Jan;9(1):34-45. Epub 2018 Oct 8.
  • Kohsaka S, Tatsuno K, Ueno T, Nagano M, Shinozaki-Ushiku A, Ushiku T, Takai D, Ikegami M, Kobayashi H, Kage H, Ando M, Hata K, Ueda H, Yamamoto S, Kojima S, Oseto K, Akaike K, Suehara Y, Hayashi T, Saito T, Takahashi F, Takahashi K, Takamochi K, Suzuki K, Nagayama S, Oda Y, Mimori K, Ishihara S, Yatomi Y, Nagase T, Nakajima J, Tanaka S, Fukayama M, Oda K, Nangaku M, Miyazono K, Miyagawa K, Aburatani H, Mano H. Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens. Cancer Sci. 110(4):1464-1479, 2019 Apr
  • Koike K, Berdyshev EV, Mikosz AM, Bronova IA, Bronoff AS, Jung JP, Beatman EL, Ni K, Cao D, Scruggs AK, Serban KA, Petrache I. Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema. Am J Respir Crit Care Med. 2019 Nov 1;200(9):1113-1125. doi: 10.1164/rccm.201812-2311OC.
  • Kato M, Sasaki S, Nakamura T, Kurokawa K, Yamada T, Ochi Y, Ihara H, Takahashi F, Takahashi K. Gastrointestinal adverse effects of nintedanib and the associated risk factors in patients with idiopathic pulmonary fibrosis. Scientific Reports 19;9(1):12062. 2019.
  • Kato M, Sasaki S, Kurokawa K, Nakamura T, Yamada T, Sasano H, Arano N, Komura M, Ihara H, Nagashima O, Shiota S, Takahashi F, Takahashi K. Usual interstitial pneumonia pattern in the lower lung lobes as a prognostic factor in idiopathic pleuroparenchymal fibroelastosis. Respiration. 97(4):319-328, 2019 Jan
  • Tateishi K, Ko R, Shukuya T, Okuma Y, Watanabe S, Kuyama S, Murase K, Tsukita Y, Ashinuma H, Nakagawa T, Uematsu K, Nakao M, Mori Y, Kaira K, Mouri A, Miyabayashi T, Sakashita H, Matsumoto Y, Tanigawa T, Koizumi T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group. Clinical Outcomes of Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma: A Retrospective Analysis of 191 Patients from the NEJ023 Study. Oncologist. 2019 Nov 26. pii: theoncologist.2019-0593. [Epub ahead of print]
  • Seyama K, Nukiwa T, Sato T, Suzuki M, Konno S, Takahashi K, Nishimura M, Steinmann K, Sorrells S, Chen J, Hayashi KI. Safety and pharmacokinetics of Alpha-1 MP (Prolastin®-C) in Japanese patients with alpha1-antitrypsin (AAT) deficiency. Respir Investig. 57(1):89-96, 2019 Jan 
  • Yamaguchi Y, Shiota S, Kusunoki Y, Hamaya H, Ishii M, Kodama Y, Akishita M, Kida K, Takahashi K, Nagase T, Fukuchi Y. Polysomnographic features of low arousal threshold in overlap syndrome involving obstructive sleep apnea and chronic obstructive pulmonary disease. Sleep Breath. 2019 Jan 26. [Epub ahead of print] 
  • Tanabe Y, Harada N, Ito J, Matsuno K, Takeshige T, Harada S, Takemasa M, Kotajima M, Ishimori A, Katsura Y, Makino F, Atsuta R, Takahashi K. Difference between two exhaled nitric oxide analyzers, NIOX VERO® electrochemical hand-held analyzer and NOA280i® chemiluminescence stationary analyzer. J Asthma. 56(2):167-172, 2019 Feb
  • Kuwasaki E, Nagaoka T, Ihara H, Tsutsumi T, Nakamura A, Yoshikawa H, Yoshida T, Watanabe J, Ichikawa M, Koyama R, Shimada N, Takahashi K. Age is an independent predictor in pathological diagnosis of sarcoidosis: a retrospective analysis of diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration. J Thorac Dis. 11(5):2175-2180, 2019 May
  • Hidayat M, Mitsuishi Y, Takahashi F, Tajima K, Yae T, Miyahara K, Hayakawa D, Winardi W, Ihara H, Koinuma Y, Wirawan A, Nurwidya F, Kato M, Kobayashi I, Sasaki S, Takamochi K, Hayashi T, Suehara Y, Moriyama M, Moriyama H, Habu S, Takahashi K. Role of FBXW7 in the quiescence of gefitinib-resistant lung cancer stem cells in EGFR-mutant non-small cell lung cancer. Bosn J Basic Med Sci. 2019 May 28. [Epub ahead of print]
  • Jin J, Togo S, Kadoya K, Tulafu M, Namba Y, Iwai M, Watanabe J, Nagahama K, Okabe T, Hidayat M, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Sasaki S, Tominaga S, Takahashi K. Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1. Respir Res. 20(1):119, 2019 Jun 11
  • Nanjo Y, Newstead MW, Aoyagi T, Zeng X, Takahashi K, Yu FS, Tateda K, Standiford TJ. Overlapping Roles for Interleukin-36 Cytokines in Protective Host Defense against Murine Legionella pneumophila Pneumonia. Infect Immun. 19;87(1). pii: e00583-18. 2019
  • Zuoyou L, Shiota S, Morio Y, Sugiyama A, Sekiya M, Iwakami SI, Ienaga H, Fukuchi Y, Takahashi K. Borderline pulmonary hypertension associated with chronic hypercapnia in chronic pulmonary disease. Respir Physiol Neurobiol. 2019 Apr;262:20-25. Epub 2019
  • Ihara H, Kikuchi K, Taniguchi H, Fujita S, Tsuruta Y, Kato M, Mitsuishi Y, Tajima K, Kodama Y, Takahashi F, Takahashi K, Azuma N. 23-valent pneumococcal polysaccharide vaccine improves survival in dialysis patients by preventing cardiac events. Vaccine. 2019 Oct 8;37(43):6447-6453. Epub 2019
  • Karasutani K, Baskoro H, Sato T, Arano N, Suzuki Y, Mitsui A, Shimada N, Kodama Y, Seyama K, Fukuchi Y, Takahashi K. Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice. J Vis Exp. 2019 Sep 26;(151).
  • Shoji T, Konno S, Niida Y, Ogi T, Suzuki M, Shimizu K, Hida Y, Kaga K, Seyama K, Naka T, Matsuno Y, Nishimura M. Familial multifocal micronodular pneumocyte hyperplasia with a novel splicing mutation in TSC1: Three cases in one family. PLoS One. 2019 Feb 22;14(2):e0212370. eCollection 2019.
  • Oba S, Inaba Y, Shibuya T, Oshima J, Seyama K, Kobayashi T, Kunugita N, Ino T. Changes in oxidative stress levels during two weeks of smoking cessation treatment and their association with nutritional characteristics in Japanese smokers. Exp Ther Med. 2019 Apr;17(4):2757-2764. Epub 2019
  • Tsuyama S, Saito T, Akazawa Y, Yanai Y, Yatagai N, Akaike K, Hayashi T, Suehara Y, Takahashi F, Takamochi K, Hashimoto T, Kajiyama Y, Tsurumaru M, Fukunaga T, Yao T. Molecular and clinicopathological analyses of esophageal carcinosarcoma with special reference to morphological change. Virchows Archiv ;475(4):415-424. Epub 2019 Aug 23.
  • Suehara Y, Okubo T, Kurihara T, Hayashi T, Kohsaka S, Kazuno S, Sano K, Hasegawa N, Miura Y, Akaike K, Kim Y, Takamochi K, Takahashi F, Ueno T, Kaneko K, Saito T. Protein Expression Profiles Corresponding to Histological Changes with Denosumab Treatment in Giant Cell Tumors of Bone. Proteomics Clin Appl. e1800147. (2019)
  • Miyazaki K, Oyanagi J, Hoshino D, Togo S, Kumagai H, Miyagi Y. Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix. Sci Rep. 2019 Jan 22;9(1):292.
  • Maruyama N, Takai T, Kamijo S, Suchiva P, Ohba M, Takeshige T, Suzuki M, Hara M, Matsuno K, Harada S, Harada N, Nakae S, Sudo K, Okuno T, Yokomizo T, Ogawa H, Okumura K, Ikeda S. Cyclooxygenase inhibition in mice heightens adaptive- and innate-type responses against inhaled protease allergen and IL-33. Allergy. 2019 Nov;74(11):2237-2240. Epub 2019
  • Mizugaki H, Hamada A, Shibata T, Hosoda F, Nakamura H, Okuma Y, Shukuya T, Umemura S, Horiike A, Fukui T, Kogure Y, Daga H, Urata Y, Yamada K, Saeki S, Fujisaka Y, Nakamura Y, Sato M, Yoshida T, Hotta T, Oizumi S, Fujiwara Y, Ohe Y, Fujiwara Y. Exploration of germline variants responsible for adverse events of crizotinib in anaplastic lymphoma kinase-positive non-small cell lung cancer by target-gene panel sequencing. Lung Cancer. 2019 Feb;128:20-25.
  • Yoh K, Takamochi K, Shukuya T, Hishida T, Tsuboi M, Sakurai H, Goto Y, Yoshida K, Ohde Y, Okumura S, Ohashi Y, Kunitoh H. Pattern of care in adjuvant therapy for resected Stage I non-small cell lung cancer: real-world data from Japan. Jpn J Clin Oncol. 2019 Jan 1;49(1):63-68.
  • Kenmotsu H, Yoh K, Mori K, Ono A, Baba T, Fujiwara Y, Yamaguchi O, Ko R, Okamoto H, Yamamoto N, Ninomiya T, Ogura T, Kato T. Phase II study of nab-paclitaxel + carboplatin for patients with non-small-cell lung cancer and interstitial lung disease. Cancer Sci. 2019 Dec;110(12):3738-3745.
  • Nakashima K, Kimura M, Akamatsu H, Daga H, Imai H, Taira T, Ko R, Hisamatsu Y, Nishino K, Sugimoto T, Miyashita Y, Takahashi T. Osimertinib for patients with EGFR T790M mutation-positive non-small-cell lung cancer and a poor performance status. Jpn J Clin Oncol. 2019 Jul 1;49(7):671-675.
  • Okazaki S, Umene K, Yamasaki J, Suina K, Otsuki Y, Yoshikawa M, Minami Y, Masuko T, Kawaguchi S, Nakayama H, Banno K, Aoki D, Saya H, Nagano O. Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma. Cancer Sci. 2019 Nov;110(11):3453-3463.
  • Koike K, Beatman EL, Schweitzer KS, Justice MJ, Mikosz AM, Ni K, Clauss MA, Petrache I. Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L558-L566.
  • Baba T, Akai F. S, Kato T, Kusumoto M, Kenmotsu H, Sugiura H, Tominaga J, Oikado K, Sata M, Endo M, Yanagawa N, Sasaki S, Iwasawa T, Saito Y, Fujiwara Y, Ohe Y, Yamazaki N, Sakamoto T, Koshiba T, Kuwano K. Radiologic features of pneumonitis associated with nivolumab in non-small-cell lung cancer and malignant melanoma. Future Oncol., 2019 Jun; 15(16): 1911-1920.
  • Murata K, Inoue Y, Kaiho M, Nakazawa T, Sasaki S, Miyake K, Matsuda S, Tanaka H. Genomic analysis of antibiotic resistance for Acinetobacter baumannii in a critical care center. Acute Med Surg., 2019 Jul; 7(1): e445.
  • Kato M, Yamada T, Kataoka S, Arai Y, Miura K, Ochi Y, Ihara H, Koyama R, Sasaki S, Takahashi K. Prognostic differences among patients with idiopathic interstitial pneumonias with acute exacerbation of varying pathogenesis: a retrospective study. Respir Res. 2019 Dec 18;20(1):287.
  • Sasaki S, Kato M, Nakamura K, Namba Y, Nagashima O, Takahashi K. Management of skin sarcoidosis with minocycline monotherapy. Respirol Case Rep. 2019 Mar 13;7(4):e00413, 2019 Mar eCollection 2019 May. 
  • Kurokawa K, Asao T, Ko R, Nagaoka T, Suzuki K, Takahashi K. Severe mediastinitis over a month after endobronchial ultrasound-guided transbronchial needle aspiration. Respirol Case Rep. 2019 Apr 9;7(5):e00426. eCollection 2019 Jul
  • Kurokawa K, Hara H, Iwakami S, Genda T, Iwakami N, Miyashita Y, Fujioka M, Sasaki S, Takahashi K. Cholestatic Liver Injury Induced by Pembrolizumab in a Patient with Lung Adenocarcinoma. Intern Med 58(22):3283-3287. Epub 2019 Nov 15.