Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao
T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H,
Takahashi K. Activation of insulin-like growth factor-1 receptor confers acquired resistance to
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11(1):140-149, 2020 Jan
Hosomi Y, Morita S, Sugawara S, Kato T, Fukuhara T, Gemma A, Takahashi K, Fujita Y, Harada T, Minato K,
Takamura K, Hagiwara K, Kobayashi K, Nukiwa T, Inoue A; North-East Japan Study Group. Gefitinib
Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth
Factor Receptor: NEJ009 Study. J Clin Oncol. 38(2):115-123, 2020 Jan
Ko Y, Asakawa K, Tobino K, Oguma T, Hirai T, Takada T, Takahashi K, Seyama K; Multicenter
Lymphangioleiomyomatosis Sirolimus Trial for Safety Study Group. Quantitative analysis of computed
tomography of the lungs in patients with lymphangioleiomyomatosis treated with sirolimus.
Heliyon 6(2):e03345. 2020 Feb 6
Tateishi K, Ko R, Shukuya T, Okuma Y, Watanabe S, Kuyama S, Murase K, Tsukita Y, Ashinuma H, Nakagawa T,
Uematsu K, Nakao M, Mori Y, Kaira K, Mouri A, Miyabayashi T, Sakashita H, Matsumoto Y, Tanigawa T, Koizumi
T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group. Clinical Outcomes of
Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma: A Retrospective
Analysis of 191 Patients from the NEJ023 Study. Oncologist 25(4): e668-e674. 2020 Apr
Sekine I, Shintani Y, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K, Dosaka-Akita H,
Takiguchi Y, Miyaoka E, Okumura M, Yoshino I. A Japanese lung cancer registry study on demographics
and treatment modalities in medically treated patients. Cancer Sci. 111(5):1685-1691, 2020 May
Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K,
Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M.
Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with
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55(5):1902150, 2020 May
Okamoto S, Suzuki K, Hayashi T, Muraki K, Nagaoka T, Nishino K, Sekimoto Y, Sasaki S, Takahashi K, Seyama
K. Transbronchial lung biopsy for the diagnosis of lymphangioleiomyomatosis: the severity of cystic
lung destruction assessed by the modified Goddard scoring system as a predictor for establishing the
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Kohsaka S, Hayashi T, Nagano M, Ueno T, Kojima S, Kawazu M, Shiraishi Y, Kishikawa S, Suehara Y, Takahashi
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Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers. J Thorac
Oncol 15(6):948-961, 2020 Jun
Kozuki T, Nogami N, Hataji O, Tsunezuka Y, Seki N, Harada T, Fujimoto N, Bessho A, Takamura K, Takahashi K,
Satouchi M, Kato T, Shukuya T, Yamashita N, Okamoto H, Shinkai T, Thoracic Oncology Research Group.
Open-label, multicenter, randomized phase II study on docetaxel plus bevacizumab or pemetrexed plus
bevacizumab for treatment of elderly (aged ≥75 years) patients with previously untreated advanced
non-squamous non-small cell lung cancer: TORG1323. Transl Lung Cancer Res 9(3): 459-470, 2020
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Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y,
Terao C, Amariuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y,
Sakata Y, Kohno T, Shiraishi K, Momozawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka
T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y,
Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N,
Minami S, Yamaguchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A,
Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T,
Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K,
Murakami Y, Nakamura Y, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y.
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility
loci across different diseases. Nat Genet. 52(7):669-679, 2020 Jun
Ihara H, Mitsuishi Y, Kato M, Takahashi F, Tajima K, Hayashi T, Hidayat M, Winardi W, Wirawan A, Hayakawa D,
Kanamori K, Matsumoto N, Yae T, Sato T, Sasaki S, Takamochi K, Suehara Y, Ogura D, Niwa SI, Suzuki K,
Takahashi K. Nintedanib Inhibits Epithelial-Mesenchymal Transition in A549 Alveolar Epithelial Cells
Through Regulation of the TGF-β/Smad Pathway. Respir Investig 58(4): 275-284, 2020 Jul
Kobayashi K, Soejima K, Fukunaga K, Shintani Y, Sekine I, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura
K, Takahashi K, Yamamoto N, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I, and on behalf of the Group on
behalf of the Japanese Joint Committee of Lung Cancer Registry. Key prognostic factors for
EGFR-mutated non-adenocarcinoma lung cancer patients in the Japanese Joint Committee of Lung Cancer
Registry Database. Lung Cancer 146: 236-243, 2020 Aug
Igawa S, Naoki K, Shintani Y, Sekine I, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K,
Yamamoto N, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I. Survival and Prognostic Factors in Elderly
Patients Receiving Second-line Chemotherapy for Relapsed Small-Cell Lung Cancer: Results from the
Japanese Joint Committee of Lung Cancer Registry. Lung Cancer. 146: 160-164, 2020 Aug
Harada N, Harada S, Ito J, Atsuta R, Hori S, Takahashi K. Mobile Health App for Japanese Adult
Patients With Asthma: Clinical Observational Study. J Med Internet Res. 22(8):e19006, 2020 Aug
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Miyawaki T, Kenmotsu H, Mori K, Miyawaki E, Mamesaya N, Kawamura T, Kobayashi H, Omori S, Wakuda K, Ono A,
Naito T, Murakami H, Harada H, Endo M, Ohde Y, Takahashi K, Takahashi T. Association Between
Clinical Tumor Burden and Efficacy of Immune Checkpoint Inhibitor Monotherapy for Advanced
Non-Small-Cell Lung Cancer. Clin Lung Cancer. 21(5): e405-e414, 2020 Sep
Hayashi T, Kohsaka S, Takamochi K, Hara K, Kishikawa S, Sano K, Takahashi F, Suehara Y, Saito T, Takahashi
K, Suzuki K, Yao T. Clinicopathological characteristics of lung adenocarcinoma with compound EGFR
mutations. Hum Pathol. 103:42-51, 2020 Sep
Takei S, Ihara H, Togo S, Nakamura A, Fujimoto Y, Watanabe J, Kurokawa K, Shibayama K, Sumiyoshi I, Ochi Y,
Iwai M, Okabe T, Chonan M, Misawa S, Ohsaka A, Takahashi K. The synergetic effect of
Imipenem-clarithromycin combination in the Mycobacteroides abscessus complex. BMC Microbiol.
20(1):316, 2020 Oct 19
Okuma Y, Ko R, Shukuya T, Tateishi K, Imai H, Iwasawa S, Miyauchi E, Kojima T, Fujita Y, Hino T, Yamanda S,
Suzuki T, Fukuizumi A, Sakakibara T, Harada T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East
Japan Study Group. Prognostic factors for patients with metastatic or recurrent thymic carcinoma
receiving palliative-intent chemotherapy. Lung Cancer. 148:122-128, 2020 Oct
Kato M, Takahashi F, Sato T, Mitsuishi Y, Tajima K, Ihara H, Nurwidya F, Baskoro H, Murakami A, Kobayashi I,
Hidayat M, Shimada N, Sasaki S, Mineki R, Fujimura T, Kumasaka T, Niwa S, Takahashi K. Tranilast
Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway. Drug Des Devel Ther. 14:
4593-4603, 2020 Oct 29
Tsuboshima K, Kurihara M, Yamanaka T, Watanabe K, Matoba Y, Seyama K. Does a gender have something
to do with clinical pictures of primary spontaneous pneumothorax? Gen Thorac Cardiovasc Surg.
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Suzuki K, Seyama K, Ebana H, Kumasaka T, Kuwatsuru R. Quantitative analysis of cystic lung diseases
by use of paired inspiratory and expiratory CT: estimation of the extent of cyst-airway communication
and evaluation of diagnostic utility. Radiology: Cardiothoracic Imaging. 2: e190097, 2020
Suzuki E, Kurihara M, Tsuboshima K, Watanabe K, Okamoto S, Seyama K. The effects of total pleural
covering on pneumothorax recurrence and pulmonary function in lymphangioleiomyomatosis patients without
history of pleurodesis or thoracic surgeries for pneumothorax. J Thorac Dis in press, 2020.
Miyazaki K, Togo S, Okamoto R, Idiris A, Kumagai H, Miyagi Y. Collective cancer cell invasion in
contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix.
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Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Harada N, Atsuta R, Fujisawa T, Kawayama T, Inoue H, Lazarus S,
Szefler S, Martinez FD, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide
step-down treatment decisions in asthma: practical considerations. Eur Respir J 2020; 56:
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Mikawa R, Sato T, Suzuki Y, Baskoro H, Kawaguchi K, Sugimoto M. p19Arf exacerbates cigarette
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Llabata P, Mitsuishi Y, Choi PS, Cai D, Francis JM, Torres-Diz M, Udeshi ND, Golomb L, Wu Z, Zhou J,
Svinkina T, Aguilera-Jimenez E, Liu Y, Carr SA, Sanchez- Cespedes M, Meyerson M, Zhang X.
Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung
Adenocarcinoma. Mol Cancer Res. 2020 Apr;18(4):574-584.
Sakamoto S, Kataoka K, Kondo Y, Kato M, Okamoto M, Mukae H, Bando M, Suda T, Yatera K, Tanino Y, Kishaba T,
Hattori N, Taguchi Y, Saito T, Nishioka Y, Kuwano K, Kishi K, Inase N, Sasaki S, Takizawa H, Johkoh T, Sakai
F, Homma S; Diffuse Lung Diseases Research Group of the Ministry of Health, Labour and Welfare, Japan.
Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised
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Tanaka K, Morita S, Ando M, Yokoyama T, Nakamura A, Yoshioka H, Ishiguro T, Miura S, Toyozawa R, Oguri T,
Daga H, Ko R, Bessho A, Tashihara M, Iwamoto Y, Hirano K, Nakanishi Y, Nakagawa K, Yamamoto N, Okamoto I.
A randomized phase 3 study of maintenance therapy with S-1 plus best supportive care versus best
supportive care after induction therapy with carboplatin plus S-1 for advanced or relapsed squamous cell
carcinoma of the lung (WJOG7512L). Cancer 2020; 125: 3648-3656.
Shukuya T, Ghai V, Amann JM, Okimoto T, Shilo K, Kim TK, Wang K, Carbone DP. Circulating MicroRNAs
and Extracellular Vesicle-Containing MicroRNAs as Response Biomarkers of Anti-programmed Cell Death
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Shukuya T, Oyanagi J, Serizawa M, Watanabe M, Yamamoto N, Koh Y. Hypoxia Inducible Factor-1α
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Yamauchi M, Nakayama H, Shiota S, Ohshima Y, Terada J, Nishijima T, Kosuga M, Kitamura T, Tachibana N, Oguri
T, Shirahama R, Aoki Y, Ishigaki K, Sugie K, Yagi T, Muraki H, Fujita Y, Takatani T, Muro S.
Potential patient screening for late-onset Pompe disease in suspected sleep apnea: a rationale and
study design for a Prospective Multicenter Observational Cohort Study in Japan (PSSAP-J Study).
Sleep Breath. 2020 Aug 18. Online ahead of print.
Sata N, Inoshita A, Suda S, Shiota S, Shiroshita N, Kawana F, Suzuki Y, Matsumoto F, Ikeda K, Kasai T.
Clinical, polysomnographic, and cephalometric features of obstructive sleep apnea with AHI over
100. Sleep Breath. 2020 Nov 17. Online ahead of print.
Nakagawa K, Hida T, Nokihara H, Morise M, Azuma K, Kim Y.K, Seto T, Takiguchi Y, Nishio M, Yoshioka H,
Kumagai T, Hotta K, Watanabe S, Goto K, Satouchi M, Kozuki T, Koyama R, Mitsudomi T, Yamamoto N, Asakawa T,
Hayashi M, Hasegawa W, Tamura T.Final progression-free survival results from the J-ALEX study of
alectinib versus crizotinib in ALK-positive non-small-cell lung cancer. Lung Cancer., 2020 Jan;
139: 195-199.
Nakazawa Y, Sakashita A, Kaizu M, Abo H, Ise Y, Shinada Y, Sugano K, Yamashiro A, Akizuki N, Kato M.
A Self-Check Program Targeting Quality Improvement in a Hospital-Based Palliative Care Consultation
Team, Japanese Society for Palliative Medicine: Issues Regarding Team Activities Identified through the
Plan-Do-Check-Act Cycle. J Palliat Med. 2020 Mar; 23(3):359-367
Matsuda Y, Tanimukai H, Inoue S, Inada S, Sugano K, Hasuo H, Yoshimura M, Wada S, Dotani C, Adachi H,
Okamoto Y, Takeuchi M, Fujisawa D, Kako J, Sasaki C, Kishi Y, Akizuki N, Inagaki M, Uchitomi Y, Matsushima
E, Okuyama T. JPOS/JASCC clinical guidelines for delirium in adult cancer patients: a summary of
recommendation statements. Jpn J Clin Oncol 2020 May; 50(5): 586-593
Kogami M, Suzuki S, Nanjo Y, Ikeda K, Tamura N, Sasaki S, Morimoto S. Complication of coronavirus
disease 2019 during remission induction therapy against anti-MDA5 antibody-positive
dermatomyositis. Rheumatol Adv Pract. 4(2): rkaa068, 2020 Nov
Sugiyama AI, Shiota S, Yamada T, Ito J, Suzuki K, Takahashi K. Sleep-related breathing disorders
associated with the characteristics of underlying congenital rare diseases of Moebius syndrome and
Poland syndrome. Respirol Case Rep 8(5): e00579, 2020 May
Jingo K, Harada N, Nishioki T,Torasawa M,Yamada T, Asao T, Takagi T,Takeshige T, Ito J, Takahashi K.
Anaphylaxis to three humanized antibodies for severe asthma: A case study. Allergy Asthma
Clin Immunol. 10;16:46. eCollection 2020 Jun
Kato Y, Kato M, Ihara H, Hayakawa E, Shibayama K, Miura K, Yamada T, Mitsuishi Y, Shukuya T, Ito J,
Matsunaga T, Sato T, Suzuki K, Takahashi K. Hermansky-Pudlak syndrome-associated pneumothorax with
rapid progression of respiratory failure: a case report. BMC Pulm Med. 20(1):259, 2020 Oct
Nishioki T, Kato M, Kataoka S, Miura K, Nagaoka T, Takahashi K. Atezolizumab‐induced fulminant type
1 diabetes mellitus occurring four months after treatment cessation. Respirology Case Reports.
8(9):doi.org/10.1002/rcr2.685, 20020 Oct
Kurokawa K, Harada N, Sasano H, Takahagi H, Takei S, Nakamura A, Kamada K, Yoshida A, Kikuchi K, Takahashi
K. Pulmonary infection due to fluoroquinolone-resistant Mycolicibacterium fortuitum: a case
report. BMC Infectious Diseases. 20: 866, 2020 Nov
Ochi Y, Kato M, Fujioka M, Hayashi M, Takagi H, Takahashi K. Thrombocytopaenia during nintedanib
treatment in a patient with idiopathic pulmonary fibrosis. Respirol Case Rep. 2020, 8: e00628.
Kurata K, Matsumoto H, Jimbo N, Yakushijin K, Yamamoto K, Ito M, Nakamachi Y, Matsuoka H, Saegusa J, Seyama
K, Itoh T, Minami H. Lymphoplasmacytic lymphoma in a patient with Birt-Hogg-Dubé syndrome.
Int J Hematol. 2020 Dec;112(6):864-870.
Hayashi T, Takamochi K, Kohsaka S, Kishikawa S, Suehara Y, Takahashi F, Suzuki K, Saito T.
Spontaneous transformation from EGFR/PTEN co-mutated lung adenocarcinoma to small cell carcinoma in
lymph node metastasis. Pathol Int 70(5):295-299 (2020)
Kumakawa Y, Hirano Y, Sueyoshi K, Ishihara T, Kondo Y, Kawasaki T, Takeuchi Y, Nakamura Y, Ishikawa K,
Watanabe Y, Saito W, Matsuda S, Nakazawa T, Sasaki S, Okamoto K, Hiroshi T. Late i.v. steroid
treatment for severe COVID-19-induced acute respiratory distress syndrome: a case report. Acute
Med Surg., 7(1): e569, 2020 Sep
Hayama N, Ihara H, Honma Y, Itoigawa Y, Kaira K, Fujii M: Severe gastritis due to pembrolizumab
treatment in a lung cancer patient. Respirol Case Rep. 8(7) : e00636, 2020 Oct