2021年度:業績(論文)

英文業績

  1. Aoyama N, Shimizu T. Approach to the seamless management of inflammatory bowel disease, considering special situations, shared decision-making, and disease burden. Digestion 2021; 102:12-17.
  2. Kumagai H, Suzuki Y, Shimizu T. Transitional care for patients with inflammatory bowel disease: Japanese experience. Digestion 2021; 102:18-24.
  3. Ando K, Fujiya M, Watanabe K, Hiraoka S, Shiga H, Tanaka S, Iijima H, Mizushima T, Kobayashi T, Nagahori M, Ikeuchi H, Kato S, Torisu T, Kobayashi K, Higashiyama M, Fukui T, Kagaya T, Esaki M, Yanai S, Abukawa D, Naganuma M, Motoya S, Saruta M, Bamba S, Sasaki M, Uchiyama K, Fukuda K, Suzuki H, Nakase H, Shimizu T, Iizuka M, Watanabe M, Suzuki Y, Hisamatsu T. A nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan. J Gastroenterol 2021; 56:1062-1079.
  4. Croft NM, Faubion WA Jr, Kugathasan S, Kierkus J, Ruemmele FM, Shimizu T, Mostafa NM, Venetucci M, Finney-Hayward T, Sanchez Gonzalez Y, Bereswill M, Lazar A, Turner D. Efficacy and safety of adalimumab in paediatric patients with moderate-to-severe ulcerative colitis (ENVISION I): a randomised, controlled, phase 3 study. Lancet Gastroenterol Hepatol 2021; 6:616-627.
  5. Shinohara MS, Nino R, Higaki T, Ishii E. Wheat protein-induced enterocolitis syndrome complicated with wheezing: An approach to diagnosis and wheat reintroduction. Cureus 2021; 13:e17141.
  6. Suzuki H, Tsutsumi Y, Morita H, Motomura K, Umehara N, Sago H, Ito Y, Arai K, Yoshioka T, Ohya Y, Saito H, Matsumoto K, Nomura I. Cord blood eosinophilia precedes neonatal onset of foodprotein- induced enterocolitis syndrome (FPIES). Allergol Int 2021; 70:262-265.
  7. Kamei K, Miyairi I, Shoji K, Arai K, Kawai T, Ogura M, Ishikura K, Sako M, Nakamura H. Live attenuated vaccines under immunosuppressive agents or biological agents: survey and clinical data from Japan. Eur J Pediatr 2021; 180:1847-1854.
  8. Taniguchi K, Inoue M, Arai K, Uchida K, Migita O, Akemoto Y, Hirayama J, Takeuchi I, Shimizu H, Hata K. Novel TNFAIP3 microdeletion in a girl with infantile-onset inflammatory bowel disease complicated by a severe perianal lesion. Hum Genome Var 2021; 8:1.
  9. Ono S, Takeshita K, Kiridoshi Y, Kato M, Kamiya T, Hoshino A, Yanagimachi M, Arai K, Takeuchi I, Toita N, Imamura T, Sasahara Y, Sugita J, Hamamoto K, Takeuchi M, Saito S, Onuma M, Tsujimoto H, Yasui M, Taga T, Arakawa Y, Mitani Y, Yamamoto N, Imai K, Suda W, Hattori M, Ohara O, Morio T, Honda K, Kanegane H. Hematopoietic cell transplantation rescues inflammatory bowel disease and dysbiosis of gut microbiota in XIAP deficiency. J Allergy Clin Immunol Pract 2021; 9:3767-3780.
  10. Mizuochi T, Arai K, Kudo T, Nambu R, Tajiri H, Aomatsu T, Abe N, Kakiuchi T, Hashimoto K, Sogo T, Takahashi M, Etani Y, Takaki Y, Konishi KI, Ishihara J, Obara H, Kakuma T, Kurei S, Yamashita Y, Mitsuyama K. Diagnostic accuracy of serum proteinase 3 antineutrophil cytoplasmic antibodies in children with ulcerative colitis. J Gastroenterol Hepatol 2021; 36:1538-1544.
  11. Yamada M, Sakamoto S, Sakamoto K, Uchida H, Shimizu S, Osumi T, Kato M, Shoji K, Arai K, Miyazaki O, Nakano N, Yoshioka T, Fukuda A, Kasahara M, Imadome K. Fatal Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis with virus-infected T cells after pediatric multivisceral transplantation: A proof-of-concept case report. Pediatr Transplant 2021; 25:e13961.
  12. Yairo A, Mandour AS, Matsuura K, Yoshida T, Ma D, Kitpipatkun P, Kato K, Cheng CJ, El-Husseiny HM, Tanaka T, Shimada K, Hamabe L, Uemura A, Takahashi K, Tanaka R. Effect of loading changes on the intraventricular pressure measured by color M-mode echocardiography in rats. Diagnostics (Basel) 2021; 11:1403.
  13. Ma D, Mandour AS, Yoshida T, Matsuura K, Shimada K, Kitpipatkun P, Uemura A, Ifuku M, Takahashi K, Tanaka R. Intraventricular pressure gradients change during the development of left ventricular hypertrophy: Effect of salvianolic acid B and beta-blocker. Ultrasound 2021; 29:229-240.
  14. Niizuma T, Obinata K, Kinoshita K, Shimizu T. Pertussis transmission in a hospital office that was confirmed on the basis of loop-mediated isothermal amplification. Juntendo Medical Journal 2021; 67:355-359.
  15. Tanaka K, Tsujii H, Okuyama M. Pediatric consultation: Present and future in Japan. International Journal of Child and Adolescent Health 2021; 14:283-290.
  16. Yamaoka Y, Hosozawa M, Sampe Mi, Sawada N, Okubo Y, Tanaka K, Yamaguchi A, Hangai M, Morisaki N. Abusive and positive parenting behavior in Japan during the COVID-19 pandemic under the state of emergency, Child Abuse Negl 2021; 120:105212.
  17. Hangai M, Piedvache A, Sawada N, Okubo Y, Sampei M, Yamaoka Y, Tanaka K, Hosozawa M, Morisaki N, Igarashi T . Children's daily lives and well-being: findings from the CORONA-CODOMO Survey. Pediatr Int 2021; 64:e14981.
  18. Kudo T, Horiuchi A, Horiuchi I, Kajiyama M, Morita A, Tanaka N. Pedunculated colorectal polyps with heads ≤ 1 cm in diameter can be resected using cold snare polypectomy. Acta Gastroenterol Belg 2021; 84:411-415.
  19. Kudo T, Horiuchi A, Kyodo R, Horiuchi I, Arai N, Kajiyama M, Tanaka N. Linked colour imaging versus white-light colonoscopy for the detection of flat colorectal lesions: A randomized controlled trial. Colorectal Dis 2021; 23:1414-1420.
  20. Kudo T, Fujii T, Maisawa SI, Sasaki M, Uchida K, Ida S, Kagimoto S, Yoden A, Shimizu T. A multicenter prospective survey on early-onset inflammatory bowel disease in Japan. Digestion 2021; 102:368-376.
  21. Kudo T, Horiuchi A, Kyodo R, Tokita K, Tanaka N, Horiuchi I, Sano K. Mucosal defect size predicts the adequacy of resection of ≤ 10 mm nonpedunculated colorectal polyps using a new cold snare polypectomy technique. Eur J Gastroenterol Hepatol 2021; 33:e484-489.
  22. Kudo T, Arai K, Uchida K, Tajiri H, Hokari R, Suzuki Y, Shimizu T. Very early-onset inflammatory bowel disease in Japan: A nationwide survey. J Gastroenterol Hepatol 2021; 36:151-155.
  23. Kudo T, Abukawa D, Nakayama Y, Segawa O, Uchida K, Jimbo K, Shimizu T. Nationwide survey of pediatric gastrointestinal endoscopy in Japan. J Gastroenterol Hepatol 2021; 36:1545-1549.
  24. Yabe K, Horiuchi A, Kudo T, Horiuchi I, Ichise Y, Kajiyama M, Tanaka N. Risk of gastrointestinal endoscopic procedure-related bleeding in patients with or without continued antithrombotic therapy. Dig Dis Sci 2021; 66:1548-1555.
  25. Hojo M, Nagahara A, Kudo T, Takeda T, Ikuse T, Matsumoto K, Ueda K, Ueyama H, Matsumoto K, Asaoka D, Shimizu T. Endoscopic findings of Helicobacter pylori gastritis in children and young adults based on the Kyoto classification of gastritis and age-associated changes. JGH Open 2021; 5:1197-1202.
  26. Kumagai H, Kudo T, Uchida K, Kunisaki R, Sugita A, Ohtsuka Y, Arai K, Kubota M, Tajiri H, Suzuki Y, Shimizu T. Transitional care for inflammatory bowel disease: A survey of Japanese pediatric gastroenterologists. Pediatr Int 2021; 63:65-71.
  27. Fujinaga S, Nishino T, Urushihara Y. Efficacy of once-daily cyclosporine in Japanese children with steroid-dependent minimal change nephrotic syndrome. Clin Exp Neprol 2021; 25:213-214.
  28. Fujinaga S, Endo S, Onuki YC.linical characteristics of patients with early relapse duling B-cell depletion after rituximab treatment for complicated steroid-dependent nephrotic syndrome. Clin Exp Neprol 2021; 25:441-442.
  29. Fujinaga S, Nakagawa M. Definition of low nocturnal bladder capacity in Japanese enuretic children. Pediatr Int 2021; 63:1410-1411.
  30. Ishizuka K, Miura K, Hashimoto T, Kaneko N, Harita Y, Yabuuchi T, Hisano M, Fujinaga S, Omori T, Yamaguchi Y, Hattori M. Degree of foot process effacement in patients with genetic focal segmental glomerulosclerosis: a single-center analysis and review of the literature. Sci Rep 2021; 8:11.
  31. Horigome A, Hisata K, Odamaki T, Iwabuchi N, Xiao JZ, Shimizu T. Colonization of supplemented bifidobacterium breve M-16V in low birth weight iInfants and Its effects on their gut microbiota weeks post administration. Front Microbiol 2021; 12:610080.
  32. Suzuki M, Minowa K, Isayama H, Shimizu T. Acute recurrent and chronic pancreatitis in children. Pediatr Int 2021; 63:137-149.
  33. Suzuki M, Nakano S, Murano Y, Miharada K. Low birth weight contributes high risk of lifestyle-related diseases: Fetal programing during developmental stage. Juntendo Medical Journal 2021; 67: 512-518.
  34. Ando H, Inomata Y, Iwanaka T, Kuroda T, Nio M, Matsui A, Yoshida M, Akiyama T, Abukawa D, Inui A, Ushijima K, Obatake M, Kasahara M, Kanamori Y, Kitagawa H, Kudo T, Kubota M, Kuroiwa M, Kono M, Koshinaga T, Komura M, Shinkai M, Suzuki T, Taguchi T, Tajiri T, Nakano M, Nosaka S, Hashimoto T, Hamada Y, Maeda K, Masumoto K, Matsufuji H, Mizuta K, Muraji T, Yagi M, Yamataka A, Yoshida H, Ishige T, Ito R, Okada T, Kubota M, Kumagai H, Komori K, Kondou H, Saito T, Sakamoto S, Sasaki T, Sasaki H, Sanada Y, Sugiura T, Suzuki M, Tainaka T, Tanaka H, Tanikawa K, Fujishiro J, Bessho K, Matsuura T, Mizuochi T, Murakami J, Yanagi T, Yokoi A, Takeuchi K, Nakayama T, Fukuzawa M, Yamashiro Y. Clinical practice guidelines for biliary atresia in Japan: A secondary publication of the abbreviated version translated into English. J Hepatobiliary Pancreat Sci 2021; 28:55-61.
  35. Numoto S, Kurahashi H, Sato A, Kubota M, Shiihara T, Okanishi T, Tanaka R, Kuk Ii, Fukuyama T, Kashiwagi M, Ikeno M, Kubota K, Akasaka M, Mimaki M, Okumura A. Acute encephalopathy in children with tuberous sclerosis complex. Orphanet J Rare Dis 2021; 16:5.
  36. Suganuma H, Collins CT, McPhee AJ, Leemaqz S, Liu G, Andersen CC, Bonney D, Gibson RA. Effect of parenteral lipid emulsion on preterm infant PUFAs and their downstream metabolites. Prostaglandins Leukot Essent Fatty Acids 2021; 164:102217.
  37. Allen E, Rumbold AR, Keir A, Collins CT, Gillis J, Suganuma H. Avoidance of bottles during the establishment of breastfeeds in preterm infants. Cochrane Database Syst Rev 10:CD005252.
  38. Nishizaki N, Obinata K, Shimizu T. Polymyxin B-Immobilized fiber column direct hemoperfusion for micro preemie infants: Is extended duration better than early start?. Blood Purif 2021; 15:1-3.
  39. Nishizaki N, Hara T, Obinata K, Shimizu T. Evaluating nocturnal polyuria in Japanese children with nocturnal enuresis. Pediatr Int 2021; 63:1339-1343.
  40. Nishizaki N, Shimizu T. Definition of low nocturnal bladder capacity in Japanese enuretic children: Reply. Pediatr Int 2021; 63:1412
  41. Nishizaki N, Shima T, Watanabe A, Obinata K, Shimizu T. Unsatisfactory short-term neurodevelopmental outcomes of preterm infants who received polymyxin B-immobilized fiber column-direct hemoperfusion for septic shock. Tohoku J Exp Med 2021; 253:275-281.
  42. Nishizaki N, Shimizu T. Is exchange transfusion for severe neonatal infection preferable to polymyxin B immobilized fiber column for direct hemoperfusion: Pros and cons. Tohoku J Exp Med 2021; 254:141-142.
  43. Matsunaga N, Hayakawa K, Terada M, Ohtsu H, Asai Y, Tsuzuki S, Suzuki S, Toyoda A, Suzuki K, Endo M, Fujii N, Suzuki M, Saito S, Uemura Y, Shibata T, Kondo M, Izumi K, Terada-Hirashima J, Mikami A, Sugiura W, Ohmagari N. Clinical epidemiology of hospitalized patients with coronavirus disease 2019 (COVID-19) in Japan: Report of the COVID-19 registry Japan. Clin Infect Dis 73: e3677-e3689.
  44. Hara H, Uemura Y, Hayakawa K, Togano T, Asai Y, Matsunaga N, Terada M, Ohtsu H, Kitajima K, Shimizu Y, Sato L, Ishikane M, Kinoshita-Iwamoto N, Shibata T, Kondo M, Izumi K, Sugiura W, Ohmagari N. Evaluation of the efficacy of anticoagulation therapy in reducing mortality in a nationwide cohort of hospitalized patients with coronavirus disease in Japan. Int J Infect Dis 2021; 112:111-116.
  45. Saito S, Asai Y, Matsunaga N, Hayakawa K, Terada M, Ohtsu H, Tsuzuki S, Ohmagari N. First and second COVID-19 waves in Japan: A comparison of disease severity and characteristics. J Infect 2021; 82:84-123.
  46. Terada M, Ohtsu H, Saito S, Hayakawa K, Tsuzuki S, Asai Y, Matsunaga N, Kutsuna S, Sugiura W, Ohmagari N. Risk factors for severity on admission and the disease progression during hospitalisation in a large cohort of patients with COVID-19 in Japan. BMJ Open 2021; 11:e047007.
  47. Shoji K, Akiyama T, Tsuzuki S, Matsunaga N, Asai Y, Suzuki S, Iwamoto N, Funaki T, Ohmagari N. Clinical characteristics of hospitalized COVID-19 in children: Report from the COVID-19 registry in Japan. J Pediatric Infect Dis Soc 2021; 10:1097-1100.
  48. Tajima T, Asai Y, Endo M, Suzuki T, Matsunaga N, Tsuzuki S, Hayakawa K, Ohmagari N. Rate of blood culture submissions in Japan as an indicator of bloodstream infections. J Infect Chemother 2021; 27:1270-1272.
  49. Tsuzuki S, Ishikane M, Matsunaga N, Morioka S, Yu J, Inagaki T, Yamamoto M, Ohmagari N. Interim 2019/2020 influenza vaccine effectiveness in Japan from October 2019 to January 2020. Jpn J Infect Dis 2021; 74:175-179.
  50. Tsuzuki S, Matsunaga N, Yahara K, Shibayama K, Sugai M, Ohmagari N. Disease burden of bloodstream infections caused by antimicrobial-resistant bacteria: A population-level study, Japan, 2015-2018. Int J Infect Dis 2021; 108:119-124.
  51. Moriyama Y, Ishikane M, Kusama Y, Matsunaga N, Tajima T, Hayakawa K, Ohmagari N. Nationwide cross sectional study of antimicrobial stewardship and antifungal stewardship programs in inpatient settings in Japan. BMC Infect Dis 2021; 21:355.
  52. Togano T, Uemura Y, Asai Y, Hayakawa K, Matsunaga N, Terada M, Ohtsu H, Suzuki S, Toyoda A, Hara H, Sato R, Ishikane M, Kinoshita- Iwamoto N, Hangaishi A, Ohmagari N. The influence of pre-admission antiplatelet and anticoagulation therapy on the illness severity in hospitalized patients with COVID-19 in Japan. J Infect Chemother 2021; 27:1498-1503.
  53. Yamada G, Hayakawa K, Asai Y, Matsunaga N, Ohtsu H, Hojo M, Hashimoto M, Kobayashi K, Sasaki R, Okamoto T, Yanagawa Y, Katagiri D, Terada M, Suzuki M, Sato L, Miyazato Y, Ishikane M, Morioka S, Saito S, Ohmagari N. External validation and update of prediction models for unfavorable outcomes in hospitalized patients with COVID-19 in Japan. J Infect Chemother 2021; 27:1043-1050.
  54. Kusama Y, Ito K, Fukuda H, Matsunaga N, Ohmagari N. National database study of trends in bacteraemia aetiology among children and adults in Japan: a longitudinal observational study. BMJ Open 2021; 11:e043774.
  55. Saito S, Hayakawa K, Tsuzuki S, Ishikane M, Nagashima M, Mezaki K, Sugiki Y, Tajima T, Matsunaga N, Ide S, Kinoshita N, Kusama Y, Fujitomo Y, Nakamoto T, Toda Y, Kaku M, Kodama EN, Ohmagari N. A matched case-case-control study of the impact of clinical outcomes and risk factors of patients with IMP-type carbapenemase-producing carbapenem-resistant enterobacteriaceae in Japan. Antimicrob Agents Chemother 2021; 65:e01483-20.
  56. Yamagishi T, Ohnishi M, Matsunaga N, Kakimoto K, Kamiya H, Okamoto K, Suzuki M, Gu Y, Sakaguchi M, Tajima T, Takaya S, Ohmagari N, Takeda M, Matsuyama S, Shirato K, Nao N, Hasegawa H, Kageyama T, Takayama I, Saito S, Wada K, Fujita R, Saito H, Okinaka K, Griffith M, Parry AE, B, Leonard J, Wakita T. Corrigendum to: Environmental sampling for severe acute respiratory syndrome coronavirus 2 during a COVID-19 outbreak on the Diamond Princess cruise ship. J Infect Dis 2021; 223:540.
  57. Endo A, Haruna H, Takubo N, Shimizu T. The effectiveness of peer-assisted learning for medical students in pediatric bedside leraning. Juntendo Medical Journal 2021; 67:367-372.
  58. Jimbo K, Okuno T, Ohgaki R, Nishikubo K, Kitamura Y, Sakurai Y, Quan L, Shoji H, Kanai Y, Shimizu T, Yokomizo T. Correction: A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy. PLoS One 2021; 16:e0247691.
  59. Sharda N, Ikuse T, Hill E, Garcia S, Czinn SJ, Bafford A, Blanchard TG, Banerjee A. Impact of andrographolide and melatonin combinatorial drug therapy on metastatic colon cancer cells and organoids. Clin Med Insights Oncol 2021; 15:11795549211012672.
  60. Baba Y, Matsuda A, Takaoka Y, Miyabayashi K, Yamada H, Yoneyama T, Yamazaki S, Inage E, Ohtsuka Y, Kantake M, Shimizu T. Role of IL-1RL1/ST2 infantile asthma. J Clin Cell Immunol 2021; 12:631-636.
  61. Hosozawa M, Cable N, Kelly Y, Sacker A. Gestational age on trajectories of social competence difficulties into adolescence. Arch Dis Child 2021; 106:1075-1080.
  62. Hosozawa M, Sacker A, Cable N. Timing of diagnosis, depression and self-harm in adolescents with autism spectrum disorder. Autism 2021; 25:70-78.
  63. Hosozawa M, Bann D, Fink E, Elsden E, Baba S, Iso H, Patalay P. Bullying victimisation in adolescence: prevalence and inequalities by gender, socioeconomic status and academic performance across 71 countries. EClinicalMedicine 2021; 41:101142.
  64. Hosozawa M, Mandy W, Cable N, Flouri E. The role of decision-making in psychological wellbeing and risky behaviours in autistic adolescents without ADHD: Longitudinal evidence from the UK millennium cohort study. J Autism Dev Disord 2021; 51:3212-3223.
  65. Yamaoka Y, Hosozawa M, Sampei M, Sawada N, Okubo Y, Tanaka K, Yamaguchi A, Hangai M, Morisaki N. Abusive and positive parenting behavior in Japan during the COVID-19 pandemic under the state of emergency. Child Abuse Negl 2021; 120:105212.
  66. Hosozawa M, Cable N, Ikeda A, Dong JY, Ikehara S, Iso H; Japan Environment and Children's Study Group. Risk of postpartum depression and very early child mistreatment among mothers reporting higher autistic traits: Evidence from the Japan environment and children's study. J Affect Disord 2021; 280(PtA):11-16.
  67. Murano Y, Shoji H, Ikeda N, Okawa N, Hayashi K, Kantake M, Morisaki N, Shimizu T, Gilmour S. Analysis of factors associated with body mass index at ages 18 and 36 months among infants born extremely preterm. JAMA Netw Open 2021; 4:e2128555.
  68. Murano Y, Ueno R, Shi S, Kawashima T, Tanoue Y, Tanaka S, Nomura S, Shoji H, Shimizu T, Nguyen H, Miyata H, Gilmour S, Yoneoka D. Impact of domestic travel restrictions on transmission of COVID-19 infection using public transportation network approach. Sci Rep 2021; 11:3109
  69. Sakuraya K, Nozu K, Murakami H, Nagano C, Horinouchi T, Fujinaga S, Iijima K, Ohtomo Y. An extremely mild clinical course in a case with LAMB2 associated nephritis diagnosed with next-generation sequencing. CEN Case Rep 2021; 10:359-363.
  70. Kinoshita S, Ando M, Ando J, Ishii M, Furukawa Y, Tomita O, Azusawa Y, Shirane S, Kishita Y, Yatsuka Y, Eguchi H, Okazaki Y, Komatsu N. Trigenic ADH5/ALDH2/ADGRV1 mutations in myelodysplasia with Usher syndrome. Heliyon 2021; 7:e07804.
  71. Osaka S, Nakano S, Mizuno T, Hiraoka Y, Minowa K, Hirai S, Mizutani A, Sabu Y, Miura Y, Shimizu T, Kusuhara H, Suzuki M, Hayashi H. A randomized trial to examine the impact of food on pharmacokinetics of 4-phenylbutyrate and change in amino acid availability after a single oral administration of 4-phenylbutyrarte in healthy volunteers. Mol Gene Metab 2021; 132:220-226.
  72. Nakajima Y, Osaka S, Mizuno T, Nakano S, Hiraoka Y, Miura Y, Suzuki M, Kusuhara H, Hayashi H. Influence of food on pharmacokinetics and pharmacodynamics of 4-phenylbutyrate in patients with urea cycle disorders. Mol Genet Metab Rep 2021; 29:100799.
  73. Miyata E, Kudo T, Ikuse T, Tokita K, Arai N, Oka I, Kyodo R, Sato M, Hosoi K, Jimbo K, Aoyagi Y, OhtsukaY, Shimizu T. Eradication therapy forHelicobacter pyloriinfection based on the antimicrobial susceptibility test in children: A single-center study over 12 years. Helicobacter 2021; 26:e12764.
  74. Akazawa Y, Fujioka T, Ide H, Yazaki K, Honjo O, Sun M, Friedberg MK. Impaired right and left ventricular function and relaxation induced by pulmonary regurgitation are not reversed by tardive antifibrosis treatment. Am J Physiol Heart Circ Physiol 2021; 321:38-51.
  75. Ifuku M, Takahashi K, Hosono Y, Iso T, Ishikawa A, Haruna H, Takubo N, Komiya K, Kurita M, Ikeda F, Watada H, Shimizu T. Left atrial dysfunction and stiffness in pediatric and adult patients with Type 1 diabetes mellitus assessed with speckle tracking echocardiography. Pediatr Diabetes 2021; 22:303-319.
  76. Shoji T, Yoshida N, TanakaA Tu.tomated detection of abnormalities from an EEG recording of epilepsy patients with a compact convolutional neural network. Biomedical Signal Processing and Control 2021; 70:103013.
  77. Matsuura K, Shiraishi K, Mandour AS, Sato K, Shimada K, Goya S, Yoshida T, Kitpipatkun P, Hamabe L, Uemura A, Yilmaz Z, Ifuku M, Iso T, Takahashi K, Tanaka R. The utility of intraventricular pressure gradient for early detection of chemotherapy-induced subclinical cardiac dysfunction in dogs. Animals (Basel) 2021; 11:1122.
  78. Akimoto S, Fukunaga H, Akiya A, Hosono Y, Iso T, Shigemitsu S, Tanaka N, Tabuchi H, Hayashi H, Sekita G, Takahashi K, Shimizu T. Deep insight into cardiac dysfunction in children and young adults with Wolff Parkinson-White syndrome using speckle tracking imaging. Heart Vessels 2021; 36:1712- 1720.
  79. Arai N, Kudo T, Tokita K, Kyodo R, Sato M, Miyata E, Hosoi K, Ikuse T, Jimbo K, Ohtsuka Y, Shimizu T. Effectiveness of biological agents in the treatment of pediatric patients with crohn's disease and anal fistulae. Digestion 2021; 102:783-788.
  80. Yoneyama T, Nakano N, Hara M, Yamada H, Izawa K, Uchida K, Kaitani A, Ando T, Kitaura J, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T. Notch signaling contributes to the establishment of sustained unresponsiveness to food allergens by oral immunotherapy. J Allergy Clin Immunol 2021; 147:1063-1076.
  81. Fukase S, Ando T, Matsuzawa M, Kimura M, Sone Y, Izawa K, Kaitani A, Kamei A, Kojima M, Nakano N, Maeda K, Shimizu T, Ogawa H, Okumura K, Nishiyama M, Murakami A, Ebihara N, Kitaura J. Pollen shells and soluble factors play non-redundant roles in the development of allergic conjunctivitis in mice. Ocul Surf 2021; 22:152-162.
  82. Yasudo H, Ando T, Maehara A, Ando T, Izawa K, Tanabe A, Kaitani A, Nomura S, Seki M, Yoshida K, Oda H, Okamoto Y, Wang H, Kamei A, Kojima M, Kimura M, Uchida K, Nakano N, Kaneko J, Ebihara N, Hasegawa K, Shimizu T, Takita J, Ogawa H, Okumura K, Ogawa S, Tamura N, Kitaura J. A possible association between a nucleotide-binding domain LRR-containing protein family PYD-containing protein 1 mutation and an autoinflammatory disease involving liver cirrhosis. Hepatology 2021; 74:2296-2299.
  83. Nishino T, Endo S, Miyano H, Takemas Y, Saito M, Umeda C, Tomii Y, Watanabe Y, Nakagawa M, Kakegawa D, Fujinaga S. Reference serum creatinine levels according to sex, age, and height in children with down syndrome. Eur J Pediatr 2021; 180: 2977-2983.
  84. Nishino T, Endo S, Miyano H, Umeda C, Tomii Y, Watanabe Y, Nakagawa M, Kakegawa D, Fujinaga S. Is the estimated glomerular filtration rate formula useful for evaluating the renal function of down syndrome? Pediatr Int 2021; 63:944-950.
  85. Awata K, Shoji H, Santosa I, Ikeda N, Murano Y, Ohkawa N, Nishizaki N, Hisata K, Kantake M, Obinata K, Shimizu T. Associations between size at birth and size at 6 years among preterm infants: a retrospective cohort study. Pediatr Int 2021; 64:e14844.
  86. Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K. Features and outcomes of children with ulcerative colitis who undergo a diagnostic change: A single-center experience. Pediatr Gastroenterol Hepatol Nutr 2021; 24:357-365.
  87. Kato M, Jimbo K, Nagata M, Endo Y, Kashiwagi K, Maruyama K, Ito N, Tokushima K, Arai N, Kyodo R, Sato M, Miyata E, Hosoi K, Inage E, Ikuse T, Fukunaga H, Kudo T, Shimizu. T. Novel pediatric granulomatosis with polyangiitis with a marked bloody pericardial effusion and bloody stool: a case report. Allergy Asthma Clin Immunol 2021; 17:124.
  88. Shimizu H, Arai K, Asahara T, Takahashi T, Tsuji H, Matsumoto S, Takeuchi I, Kyodo R, Yamashiro Y. Stool preparation under anaerobic conditions contributes to retention of obligate anaerobes: potential improvement for fecal microbiota transplantation. BMC Microbiol 2021; 21:275.
  89. Shimizu H, Arai K, Takeuchi I, Minowa K, Hosoi K, Sato M, Oka I, Kaburaki Y, Shimizu T. Long-term durability of infliximab for pediatric ulcerative colitis: A retrospective data review in a tertiary children's hospital in Japan. Pediatr Gastroenterol Hepatol Nutr 2021; 24:7-18.
  90. Miura M, Shimizu H, Saito D, Miyoshi J, Matsuura M, Kudo T, Hirayama D, Yoshida M, Arai K, Iwama I, Nakase H, Shimizu T, Hisamatsu T. Multicenter, cross-sectional, observational study on Epstein-Barr viral infection status and thiopurine use by age group in patients with inflammatory bowel disease in Japan (EBISU study). J Gastroenterol 2021; 56:1080-1091.
  91. Funato M, Tsunematsu Y, Yamazaki F, Tamura C, Kumamoto T, Takagi M, Kato S, Sugimura H, Tamura K. Characteristics of Li-Fraumeni Syndrome in Japan; A review study by the special committee of JSHT. Cancer Sci 2021; 112:2821-2834.
  92. Kumamoto T, Yamazaki F, Nakano Y, Tamura C, Tashiro S, Hattori H, Nakagawara A, Tsunematsu Y. Medical guidelines for Li-Fraumeni syndrome 2019, version 1.1. Int J Clin Oncol 2021; 26:2161-2178.