業績(論文)

【英文原著】

2018年度

  1. Araki, E., Yamashita, S., Arai, H., Yokote, K., Satoh, J., Inoguchi, T., Nakamura, J., Maegawa, H., Yoshioka, N., Tanizawa, Y., Watada, H., Suganami, H., Ishibashi, S. Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial. Diabetes Care 41(3): 538-546, 2018
  2. Chinzei, K., Shimizu, A., Mori, K., Harada, K., Takeda, H., Hashizume, M., Ishizuka, M., Kato, N., Kawamori, R., Kyo, S., Nagata, K., Yamane, T., Sakuma, I., Ohe, K., Mitsuishi, M. Regulatory Science on AI-based Medical Devices and Systems. Advanced Biomedical Engineering 7: 118-123, 2018
  3. Cigliola, V., Ghila, L., Thorel, F., van Gurp, L., Baronnier, D., Oropeza, D., Gupta, S., Miyatsuka, T., Kaneto, H., Magnuson, M. A., Osipovich, A. B., Sander, M., Wright, C. E. V., Thomas, M. K., Furuyama, K., Chera, S., Herrera, P. L. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon(+) alpha-cells. Nat Cell Biol 20(11): 1267-1277, 2018
  4. Furukawa, Y., Tamura, Y., Takeno, K., Funayama, T., Kaga, H., Suzuki, R., Watanabe, T., Kakehi, S., Kanazawa, A., Kawamori, R., Watada, H. Impaired peripheral insulin sensitivity in non-obese Japanese patients with type 2 diabetes mellitus and fatty liver. J Diabetes Investig 9(3): 529-535, 2018
  5. Goto, H., Mita, T., Fujitani, Y., Fujimoto, S., Takahashi, K., Satoh, H., Hirose, T., Hiyoshi, T., Ai, M., Okada, Y., Nishimura, H., Kuroda, H., Matsubara, T., Gosho, M., Ishii, H., Watada, H. Effects of linagliptin versus voglibose on treatment-related quality of life in patients with type 2 diabetes: sub-analysis of the L-STEP study. Endocr J 65(5): 657-668, 2018
  6. Honda, A., Komiya, K., Hara, A., Fukunaka, A., Suzuki, L., Miyatsuka, T., Ogihara, T., Fujitani, Y., Watada, H. Normal pancreatic β-cell function in mice with Rip-Cre-mediated inactivation of p62/SQSTM1. Endocrine Journal 65(1): 83-89, 2018
  7. Horikawa, Y., Enya, M., Mabe, H., Fukushima, K., Takubo, N., Ohashi, M., Ikeda, F., Hashimoto, K. I., Watada, H., Takeda, J. NEUROD1-deficient diabetes (MODY6): Identification of the first cases in Japanese and the clinical features. Pediatr Diabetes 19(2): 236-242, 2018
  8. Irie, Y., Katakami, N., Mita, T., Takahara, M., Matsuoka, T. A., Gosho, M., Watada, H., Shimomura, I., Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis, C. Evaluation of the Effect of Alogliptin on Tissue Characteristics of the Carotid Wall: Subanalysis of the SPEAD-A Trial. Diabetes Ther 9(1): 317-329, 2018
  9. Kaku, K., Yamada, Y., Watada, H., Abiko, A., Nishida, T., Zacho, J., Kiyosue, A. Safety and efficacy of once-weekly semaglutide vs additional oral antidiabetic drugs in Japanese people with inadequately controlled type 2 diabetes: A randomized trial. Diabetes Obes Metab 20(5): 1202-1212, 2018
  10. Kamitani, M., Miyatsuka, T., Miura, M., Azuma, K., Suzuki, L., Himuro, M., Katahira, T., Nishida, Y., Fujitani, Y., Watada, H. Heterogeneity of autophagic status in pancreatic β cells under metabolic stress. Biochem Biophys Res Commun 496(2): 328-334, 2018
  11. Kanda, E., Kashihara, N., Matsushita, K., Usui, T., Okada, H., Iseki, K., Mikami, K., Tanaka, T., Wada, T., Watada, H., Ueki, K., Nangaku, M., Research Working Group for Establishing Guidelines for Clinical Evaluation of Chronic Kidney Disease. Guidelines for clinical evaluation of chronic kidney disease : AMED research on regulatory science of pharmaceuticals and medical devices. Clin Exp Nephrol 22(6): 1446-1475, 2018
  12. Katahira, T., Kanazawa, A., Shinohara, M., Koshibu, M., Kaga, H., Mita, T., Tosaka, Y., Komiya, K., Miyatsuka, T., Ikeda, F., Azuma, K., Takayanagi, N., Ogihara, T., Ohmura, C., Miyachi, A., Mineo, E., Yamashita, S., Watada, H. Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry. J Endocr Soc 3(1): 42-51, 2018
  13. Katakami, N., Mita, T., Gosho, M., Takahara, M., Irie, Y., Yasuda, T., Matsuoka, T. A., Osonoi, T., Watada, H., Shimomura, I. Clinical Utility of Carotid Ultrasonography in The Prediction of Cardiovascular Events in Patients with Diabetes: A Combined Analysis of Data Obtained in Five Longitudinal Studies. J Atheroscler Thromb 25(10): 1053-1066, 2018
  14. Katakami, N., Mita, T., Irie, Y., Takahara, M., Matsuoka, T. A., Gosho, M., Watada, H., Shimomura, I., Sitagliptin Preventive study of Intima-media thickness Evaluation (SPIKE) Collaborators. Effect of sitagliptin on tissue characteristics of the carotid wall in patients with type 2 diabetes: a post hoc sub-analysis of the sitagliptin preventive study of intima-media thickness evaluation (SPIKE). Cardiovasc Diabetol 17(1): 24, 2018
  15. Katakami, N., Mita, T., Takahara, M., Hashigami, K., Kawashima, M., Shimomura, I., Watada, H., J-DISCOVER study group. Rationale and Design for the J-DISCOVER Study: DISCOVERing the Treatment Reality of Type 2 Diabetes in a Real-World Setting in Japan-A Protocol. Diabetes Ther 9(1): 165-175, 2018
  16. Kawamori, R., Haneda, M., Suzaki, K., Cheng, G., Shiki, K., Miyamoto, Y., Solimando, F., Lee, C., Lee, J., George, J. Empagliflozin as add-on to linagliptin in a fixed-dose combination in Japanese patients with type 2 diabetes: Glycaemic efficacy and safety profile in a 52-week, randomized, placebo-controlled trial. Diabetes Obes Metab 20(9): 2200-2209, 2018
  17. Kosiborod, M., Gomes, M. B., Nicolucci, A., Pocock, S., Rathmann, W., Shestakova, M. V., Watada, H., Shimomura, I., Chen, H., Cid-Ruzafa, J., Fenici, P., Hammar, N., Surmont, F., Tang, F., Khunti, K., DISCOVER investigators. Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program). Cardiovasc Diabetol 17(1): 150, 2018
  18. Kudoh, A., Satoh, H., Hirai, H., Watanabe, T., Shimabukuro, M. Preliminary Evidence for Adipocytokine Signals in Skeletal Muscle Glucose Uptake. Front Endocrinol (Lausanne) 9: 295, 2018
  19. Kurozumi, A., Okada, Y., Satoh, H., Inoue, I., Chimori, H., Akita, E., Shiraiwa, T., Fujitani, Y., Mita, T., Gosho, M., Watada, H. Effects of linagliptin monotherapy compared with voglibose on postprandial lipid profiles in Japanese patients with type 2 diabetes: linagliptin study of effects on postprandial blood glucose (L-STEP) sub-study 1. Endocr J 65(4): 415-425, 2018
  20. Masuyama, A., Mita, T., Azuma, K., Osonoi, Y., Nakajima, K., Goto, H., Nishida, Y., Miyatsuka, T., Mitsumata, M., Watada, H. Defective autophagy in vascular smooth muscle cells enhances atherosclerotic plaque instability. Biochem Biophys Res Commun 505(4): 1141-1147, 2018
  21. Mita, T., Hiyoshi, T., Yoshii, H., Chimori, H., Ikeda, K., Sato, J., Watada, H. Study Protocol for the Initial Choice of DPP-4 Inhibitor in Japanese Patients with Type 2 diabetes Mellitus: Effect of Linagliptin on QOL (INTEL-QOL) Trial. Diabetes Ther 9(3): 1403-1412, 2018
  22. Miura, M., Miyatsuka, T., Katahira, T., Sasaki, S., Suzuki, L., Himuro, M., Nishida, Y., Fujitani, Y., Matsuoka, T. A., Watada, H. Suppression of STAT3 signaling promotes cellular reprogramming into insulin-producing cells induced by defined transcription factors. EBioMedicine 36: 358-366, 2018
  23. Ogata, E., Asahi, K., Yamaguchi, S., Iseki, K., Sato, H., Moriyama, T., Yamagata, K., Tsuruya, K., Fujimoto, S., Narita, I., Konta, T., Kondo, M., Shibagaki, Y., Kasahara, M., Watanabe, T., Shimabukuro, M. Low fasting plasma glucose level as a predictor of new-onset diabetes mellitus on a large cohort from a Japanese general population. Sci Rep 8(1): 13927, 2018
  24. Ohkuma, T., Ninomiya, T., Tomiyama, H., Kario, K., Hoshide, S., Kita, Y., Inoguchi, T., Maeda, Y., Kohara, K., Tabara, Y., Nakamura, M., Ohkubo, T., Watada, H., Munakata, M., Ohishi, M., Ito, N., Nakamura, M., Shoji, T., Vlachopoulos, C., Aboyans, V., Yamashina, A., collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI). Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis. Atherosclerosis 275: 141-148, 2018
  25. Oshima, M., Toyama, T., Haneda, M., Furuichi, K., Babazono, T., Yokoyama, H., Iseki, K., Araki, S., Ninomiya, T., Hara, S., Suzuki, Y., Iwano, M., Kusano, E., Moriya, T., Satoh, H., Nakamura, H., Shimizu, M., Hara, A., Makino, H., Wada, T., Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan. Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes. PLoS One 13(8): e0201535, 2018
  26. Osonoi, Y., Mita, T., Azuma, K., Nakajima, K., Masuyama, A., Goto, H., Nishida, Y., Miyatsuka, T., Fujitani, Y., Koike, M., Mitsumata, M., Watada, H. Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. Autophagy 14(11): 1991-2006, 2018
  27. Sagesaka, H., Sato, Y., Someya, Y., Tamura, Y., Shimodaira, M., Miyakoshi, T., Hirabayashi, K., Koike, H., Yamashita, K., Watada, H., Aizawa, T. Type 2 Diabetes: When Does It Start?. J Endocr Soc 2(5): 476-484, 2018
  28. Shioya-Yamada, M., Shimada, K., Nishitani-Yokoyama, M., Sai, E., Takeno, K., Tamura, Y., Watada, H., Kawamori, R., Daida, H., Kawai, S. Association Between Visceral Fat Accumulation and Exercise Tolerance in Non-Obese Subjects Without Diabetes. J Clin Med Res 10(8): 630-635, 2018
  29. Someya, Y., Tamura, Y., Suzuki, R., Kaga, H., Kadowaki, S., Sugimoto, D., Kakehi, S., Funayama, T., Furukawa, Y., Takeno, K., Sato, J., Kanazawa, A., Kawamori, R., Watada, H. Characteristics of Glucose Metabolism in Underweight Japanese Women. J Endocr Soc 2(3): 279-289, 2018
  30. Suzuki, L., Miyatsuka, T., Himuro, M., Nishio, R., Goto, H., Uchida, T., Nishida, Y., Kanazawa, A., Watada, H. Everolimus Directly Suppresses Insulin Secretion Independently of Cell Growth Inhibition. J Endocr Soc 2(7): 589-596, 2018
  31. Taira, M., Imamura, M., Takahashi, A., Kamatani, Y., Yamauchi, T., Araki, S., Tanaka, N., van Zuydam, N., Ahlqvist, E., Toyoda, M., Umezono, T., Kawai, K., Imanishi, M., Watada, H., Suzuki, D., Maegawa, H., Babazono, T., Kaku, K., Kawamori, R., SUMMIT Consortium., Groop LC., McCarthy, MI., Kadowaki, T., Maeda, S. A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes. PLoS One 13(12): e0208654, 2018
  32. Tanaka, R., Masuda, H., Fujimura, S., Ito-Hirano, R., Arita, K., Kakinuma, Y., Hagiwara, H., Kado, M., Hayashi, A., Mita, T., Ogawa, T., Watada, H., Mizuno, H., Sawada, N., Asahara, T. Quality-Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells. Stem Cells Transl Med 7(5): 428-438, 2018,
  33. Terauchi, Y., Yamada, Y., Watada, H., Nakatsuka, Y., Shiosakai, K., Washio, T., Taguchi, T. Efficacy and safety of the G protein-coupled receptor 119 agonist DS-8500a in Japanese type 2 diabetes mellitus patients with inadequate glycemic control on sitagliptin: A phase 2 randomized placebo-controlled study. J Diabetes Investig 9(6): 1333-1341, 2018
  34. Tomiyama, H., Ohkuma, T., Ninomiya, T., Mastumoto, C., Kario, K., Hoshide, S., Kita, Y., Inoguchi, T., Maeda, Y., Kohara, K., Tabara, Y., Nakamura, M., Ohkubo, T., Watada, H., Munakata, M., Ohishi, M., Ito, N., Nakamura, M., Shoji, T., Vlachopoulos, C., Yamashina, A., collaborative group for J-BAVEL-IAD (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies to Examine the Significance of Inter-Arm Blood Pressure Difference). Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis. Hypertension 71(6): 1030-1038, 2018
  35. Uesato, T., Ogihara, T., Hara, A., Iida, H., Miyatsuka, T., Fujitani, Y., Takeda, S., Watada, H. Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice. Journal of Endocrine Society 2(3): 207-219, 2018
  36. Yamada, Y., Terauchi, Y., Watada, H., Nakatsuka, Y., Shiosakai, K., Washio, T., Taguchi, T. Efficacy and Safety of GPR119 Agonist DS-8500a in Japanese Patients with Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled, 12-Week Study. Adv Ther 35(3): 367-381, 2018

2017年度

  1. Yamada Y., Terauchi Y., Watada H., Nakatsuka Y., Shiosakai K., Washio T., Taguchi T. Efficacy and Safety of GPR119 Agonist DS-8500a in Japanese Patients with Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled, 12-Week Study. Adv Ther 35(3): 367-381, 2018
  2. Uesato T., Ogihara T., Hara A., Iida H., Miyatsuka T., Fujitani Y., Takeda S., Watada H. Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice Journal of Endocrine Society 2(3): 207-219, 2018
  3. Someya Y., Tamura Y., Suzuki R., Kaga H., Kadowaki S., Sugimoto D., Kakehi S., Funayama T., Furukawa Y., Takeno K., Sato J., Kanazawa A., Kawamori R., Watada H. Characteristics of Glucose Metabolism in Underweight Japanese Women J Endocr Soc 2(3): 279-289, 2018
  4. Katakami N., Mita T., Takahara M., Hashigami K., Kawashima M., Shimomura I., Watada H., J. Discover study group. Rationale and Design for the J-DISCOVER Study: DISCOVERing the Treatment Reality of Type 2 Diabetes in a Real-World Setting in Japan-A Protocol Diabetes Ther 9(1): 165-175, 2018
  5. Katakami N., Mita T., Irie Y., Takahara M., Matsuoka T. A., Gosho M., Watada H., Shimomura I., Sitagliptin Preventive study of Intima-media thickness Evaluation, Collaborators. Effect of sitagliptin on tissue characteristics of the carotid wall in patients with type 2 diabetes: a post hoc sub-analysis of the sitagliptin preventive study of intima-media thickness evaluation (SPIKE) Cardiovasc Diabetol 17(1): 24, 2018
  6. Katakami N., Mita T., Gosho M., Takahara M., Irie Y., Yasuda T., Matsuoka T. A., Osonoi T., Watada H., Shimomura I. Clinical Utility of Carotid Ultrasonography in The Prediction of Cardiovascular Events in Patients with Diabetes: A Combined Analysis of Data Obtained in Five Longitudinal Studies J Atheroscler Thromb 2018
  7. Kamitani M., Miyatsuka T., Miura M., Azuma K., Suzuki L., Himuro M., Katahira T., Nishida Y., Fujitani Y., Watada H. Heterogeneity of autophagic status in pancreatic β cells under metabolic stress. Biochem Biophys Res Commun 496(2): 328-334, 2018
  8. Irie Y., Katakami N., Mita T., Takahara M., Matsuoka T. A., Gosho M., Watada H., Shimomura I., Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis, Collaborators. Evaluation of the Effect of Alogliptin on Tissue Characteristics of the Carotid Wall: Subanalysis of the SPEAD-A Trial Diabetes Ther 9(1): 317-329, 2018
  9. Horikawa Y., Enya M., Mabe H., Fukushima K., Takubo N., Ohashi M., Ikeda F., Hashimoto K. I., Watada H., Takeda J. NEUROD1-deficient diabetes (MODY6): Identification of the first cases in Japanese and the clinical features Pediatr Diabetes 19(2): 236-242, 2018
  10. Honda A., Komiya K., Hara A., Fukunaka A., Suzuki L., Miyatsuka T., Ogihara T., Fujitani Y., Watada H. Normal pancreatic β-cell function in mice with Rip-Cre-mediated inactivation of p62/SQSTM1 Endocrine Journal 65(1): 83-89, 2018
  11. Araki E., Yamashita S., Arai H., Yokote K., Satoh J., Inoguchi T., Nakamura J., Maegawa H., Yoshioka N., Tanizawa Y., Watada H., Suganami H., Ishibashi S. Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial. Diabetes Care 41(3): 538-546, 2018
  12. Watada H., Imori M., Li P., Iwamoto N. Insulin lispro 25/75 and insulin lispro 50/50 as starter insulin in Japanese patients with type 2 diabetes: subanalysis of the CLASSIFY randomized trial. Endocr J 64(7): 705-717, 2017
  13. Takahashi A., Ohira T., Hosoya M., Yasumura S., Nagai M., Ohira H., Hashimoto S., Satoh H., Sakai A., Ohtsuru A., Kawasaki Y., Suzuki H., Kobashi G., Ozasa K., Yamashita S., Kamiya K., Abe M., Fukushima Health Management Survey G. Effect of evacuation on liver function after the Fukushima Daiichi Nuclear Power Plant accident: The Fukushima Health Management Survey. J Epidemiol 27(4): 180-185, 2017
  14. Suzuki L., Kanazawa A., Uzawa H., Osonoi Y., Masuyama A., Azuma K., Takeno K., Takayanagi N., Sato J., Someya Y., Komiya K., Goto H., Mita T., Ikeda F., Ogihara T., Shimizu T., Ohmura C., Saito M., Osonoi T., Watada H. Safety and efficacy of metformin up-titration in Japanese patients with type 2 diabetes mellitus treated with vildagliptin and low-dose metformin Expert Opin Pharmacother 18(18): 1921-1928, 2017
  15. Sugaya Y., Satoh H.「Liver-specific G0 /G1 switch gene 2 (G0s2) expression promotes hepatic insulin resistance by exacerbating hepatic steatosis in male Wistar rats.」J Diabetes 9(8): 754-763, 2017
  16. Shigiyama F., Kumashiro N., Furukawa Y., Funayama T., Takeno K., Wakui N., Ikehara T., Nagai H., Taka H., Fujimura T., Uchino H., Tamura Y., Watada H., Nemoto T., Shiraga N., Sumino Y., Hirose T. Characteristics of hepatic insulin-sensitive nonalcoholic fatty liver disease. Hepatol Commun. 1(7): 634-647, 2017
  17. Satoh H., Ohira T., Moriya C., Inoue I., Kuribayashi S., Seino H., Hirai H., Hiyoshi T., Watada H., L-CGM Study Group. Effects of linagliptin vs. voglibose on daily glucose excursions during continuous glucose monitoring of Japanese type 2 diabetes patients (L-CGM): A randomized, open-label, two-arm, parallel comparative trial. Diabetes Metab 43(6): 550-553, 2017
  18. Sato J., Kanazawa A., Makita S., Hatae C., Komiya K., Shimizu T., Ikeda F., Tamura Y., Ogihara T., Mita T., Goto H., Uchida T., Miyatsuka T., Takeno K., Shimada S., Ohmura C., Watanabe T., Kobayashi K., Miura Y., Iwaoka M., Hirashima N., Fujitani Y., Watada H. A randomized controlled trial of 130 g/day low-carbohydrate diet in type 2 diabetes with poor glycemic control. Clin Nutr 36(4): 992-1000, 2017
  19. Sato J., Kanazawa A., Hatae C., Makita S., Komiya K., Shimizu T., Ikeda F., Tamura Y., Ogihara T., Mita T., Goto H., Uchida T., Miyatsuka T., Ohmura C., Watanabe T., Kobayashi K., Miura Y., Iwaoka M., Hirashima N., Watada H. One year follow-up after a randomized controlled trial of a 130 g/day low-carbohydrate diet in patients with type 2 diabetes mellitus and poor glycemic control PLoS One 12(12): e0188892, 2017
  20. Sato J., Kanazawa A., Azuma K., Ikeda F., Goto H., Komiya K., Kanno R., Tamura Y., Asahara T., Takahashi T., Nomoto K., Yamashiro Y., Watada H. Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study Sci Rep 7(1): 12115, 2017
  21. Osada T., Suzuki R., Ogawa A., Tanaka M., Hori M., Aoki S., Tamura Y., Watada H., Kawamori R. Functional subdivisions of the hypothalamus using areal parcellation and their signal changes related to glucose metabolism NeuroImage 162: 1-12, 2017
  22. Ohkuma T., Tomiyama H., Ninomiya T., Kario K., Hoshide S., Kita Y., Inoguchi T., Maeda Y., Kohara K., Tabara Y., Nakamura M., Ohkubo T., Watada H., Munakata M., Ohishi M., Ito N., Nakamura M., Shoji T., Vlachopoulos C., Yamashina A. Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension. Circ J. 81(10): 1540-1542, 2017
  23. Ohkuma T., Ninomiya T., Tomiyama H., Kario K., Hoshide S., Kita Y., Inoguchi T., Maeda Y., Kohara K., Tabara Y., Nakamura M., Ohkubo T., Watada H., Munakata M., Ohishi M., Ito N., Nakamura M., Shoji T., Vlachopoulos C., Yamashina A., Collaborative Group for, J. Bavel. Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease: An Individual Participant Data Meta-Analysis. Hypertension 69(6): 1045-1052, 2017
  24. Odawara M., Kawamori R., Tajima N., Iwamoto Y., Kageyama S., Yodo Y., Ueki F., Hotta N. Long-term treatment study of global standard dose metformin in Japanese patients with type 2 diabetes mellitus. Diabetol Int 8(3): 286-295, 2017
  25. Nishioka K., Uchida T., Usui C., Tanaka R., Matsushima T., Matsumoto Y., Nakamura I., Nishioka K., Hattori N. High prevalence of anti-TSH receptor antibody in fibromyalgia syndrome. Int J Rheum Dis 20(6): 685-690, 2017
  26. Mita T., Katakami N., Yoshii H., Onuma T., Kaneto H., Osonoi T., Shiraiwa T., Kosugi K., Umayahara Y., Yamamoto T., Yokoyama H., Kuribayashi N., Jinnouchi H., Gosho M., Shimomura I., Watada H., Collaborators on the Study of Preventive. Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) Trial. Erratum. Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). Diabetes Care 2016;39:139-148. Diabetes Care 40(6): 808, 2017
  27. Mita T., Katakami N., Shiraiwa T., Yoshii H., Onuma T., Kuribayashi N., Osonoi T., Kaneto H., Kosugi K., Umayahara Y., Yamamoto T., Matsumoto K., Yokoyama H., Tsugawa M., Gosho M., Shimomura I., Watada H., Collaborators on the Study of Preventive. Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) Trial. Erratum. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE). A Randomized Controlled Trial. Diabetes Care 2016;39:455-464. Diabetes Care 40(6): 808, 2017
  28. Mita T., Katakami N., Shiraiwa T., Yoshii H., Gosho M., Shimomura I., Watada H. Dose-Dependent Effect of Sitagliptin on Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Post Hoc Analysis Diabetes Ther 8(5): 1135-1146, 2017
  29. Mita T., Katakami N., Shiraiwa T., Yoshii H., Gosho M., Ishii H., Shimomura I., Watada H., Spike Trial Site Investigators. The Influence of Sitagliptin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Prespecified Sub-Analysis. Diabetes Ther 8(3): 693-704, 2017
  30. Katakami N., Mita T., Yoshii H., Shiraiwa T., Yasuda T., Okada Y., Umayahara Y., Kaneto H., Osonoi T., Yamamoto T., Kuribayashi N., Maeda K., Yokoyama H., Kosugi K., Ohtoshi K., Hayashi I., Sumitani S., Tsugawa M., Ohashi M., Taki H., Nakamura T., Kawashima S., Sato Y., Watada H., Shimomura I., UTOPIA study investigators. Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study. Diabetes Ther. 8(5): 999-1013, 2017
  31. Kaga H., Tamura Y., Takeno K., Kakehi S., Funayama T., Furukawa Y., Nishitani-Yokoyama M., Shimada K., Daida H., Aoki S., Giacca A., Kanazawa A., Kawamori R., Watada H. Correlates of insulin clearance in apparently healthy non-obese Japanese men Sci Rep 7(1): 1462, 2017
  32. Ji L., Bonnet F., Charbonnel B., Gomes M. B., Kosiborod M., Khunti K., Nicolucci A., Pocock S., Rathmann W., Shestakova M. V., Shimomura I., Watada H., Fenici P., Hammar N., Hashigami K., Macaraeg G., Surmont F., Medina J. Towards an improved global understanding of treatment and outcomes in people with type 2 diabetes: Rationale and methods of the DISCOVER observational study program. J Diabetes Complications 31(7): 1188-1196, 2017
  33. Honda A., Uchida T., Komiya K., Goto H., Takeno K., Sato J., Suzuki R., Himuro M., Watada H. RELATIONSHIP BETWEEN THE EFFECTIVENESS OF INORGANIC IODINE AND THE SEVERITY OF GRAVES' THYROTOXICOSIS: A RETROSPECTIVE STUDY. Endocr Pract 23(12): 1408-1413, 2017
  34. Hamamura M., Mita T., Osonoi Y., Osonoi T., Saito M., Tamasawa A., Nakayama S., Someya Y., Ishida H., Gosho M., Kanazawa A., Watada H. Relationships Among Conventional Cardiovascular Risk Factors and Lifestyle Habits With Arterial Stiffness in Type 2 Diabetic Patients. J Clin Med Res 9(4): 297-302, 2017
  35. Furukawa Y., Tamura Y., Takeno K., Funayama T., Kaga H., Suzuki R., Watanabe T., Kakehi S., Kanazawa A., Kawamori R., Watada H. Impaired peripheral insulin sensitivity in non-obese Japanese patients with type 2 diabetes mellitus and fatty liver. J Diabetes Investig. 2017
  36. Fukunaka A., Fukada T., Bhin J., Suzuki L., Tsuzuki T., Takamine Y., Bin B. H., Yoshihara T., Ichinoseki-Sekine N., Naito H., Miyatsuka T., Takamiya S., Sasaki T., Inagaki T., Kitamura T., Kajimura S., Watada H., Fujitani Y. Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression Plos Genetics 13(8): e1006950, 2017
  37. Eshima H., Tamura Y., Kakehi S., Kurebayashi N., Murayama T., Nakamura K., Kakigi R., Okada T., Sakurai T., Kawamori R., Watada H. Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle. Physiol Rep 5(7): e13250, 2017

2016年度

  1. Yokomichi H., Nagai A., Hirata M., Kiyohara Y., Muto K., Ninomiya T., Matsuda K., Kamatani Y., Tamakoshi A., Kubo M., Nakamura Y., BioBank Japan Cooperative Hospital Group., Yamagata Z. Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort J Epidemiol 27(3S): S98-S106, 2017
  2. Yamamoto Y., Miyatsuka T., Sasaki S., Miyashita K., Kubo F., Shimo N., Takebe S., Watada H., Kaneto H., Matsuoka T., Shimomura I. Preserving expression of Pdx1 improves β-cell failure in diabetic mice. Biochem Biophys Res Commun 483(1): 418-424, 2017
  3. Watada H., Su Q., Li P., Iwamoto N., Qian L., Yang WY. Comparison of insulin lispro mix 25 with insulin lispro mix 50 as an insulin starter in Asian patients with type 2 diabetes: a phase 4, open-label, randomized trial (CLASSIFY study). Diabetes Metab Res Rev 33(1): e2816, 2017
  4. Uchida T., Nishimoto K., Fukumura Y., Asahina M., Goto H., Kawano Y., Shimizu F., Tsujimura A., Seki T., Mukai K., Kabe Y., Suematsu M., Sanchez G. C., Yao T., Horie S., Watada H. Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study. Endocr Pathol 28(1): 27-35, 2017
  5. Suzuki L., Hirayama S., Fukui M., Sasaki M., Hiroi S., Ayaori M., Terai S., Tozuka M., Watada H., Miida T. Lipoprotein-X in cholestatic patients causes xanthomas and promotes foam cell formation in human macrophages. Journal of Clinical Lipidology 11(1): 110-118, 2017
  6. Sato J., Uchida T., Komiya K., Goto H., Takeno K., Suzuki R., Honda A., Himuro M., Watada H. Comparison of the therapeutic effects of prednisolone and nonsteroidal anti-inflammatory drugs in patients with subacute thyroiditis. Endocrine 55(1): 209-214, 2017
  7. Sakai A., Nakano H., Ohira T., Hosoya M., Yasumura S., Ohtsuru A., Satoh H., Kawasaki Y., Suzuki H., Takahashi A., Sugiura Y., Shishido H., Hayashi Y., Takahashi H., Kobashi G., Ozasa K., Hashimoto S., Ohto H., Abe M., and for the Fukushima Health Management Survey Group. Persistent prevalence of polycythemia among evacuees 4 years after the Great East Japan Earthquake: A follow-up study. Preventive Medicine Reports 5: 251-256, 2017
  8. Saito D., Kanazawa A., Shigihara N., Sato F., Uchida T., Sato J., Goto H., Miyatsuka T., Ikeda F., Ogihara T., Ohmura C., Watada H. Efficacy and Safety of Vildagliptin as an Add-On Therapy in Inadequately Controlled Type 2 Diabetes Patients Treated With Basal Insulin. J Clin Med Res 9(3): 193-199, 2017
  9. Sai E., Shimada K., Yokoyama T., Hiki M., Sato S., Hamasaki N., Maruyama M., Morimoto R., Miyazaki T., Fujimoto S., Tamura Y., Aoki S., Watada H., Kawamori R., Daida H. Myocardial triglyceride content in patients with left ventricular hypertrophy: comparison between hypertensive heart disease and hypertrophic cardiomyopathy. Heart Vessels 32(2): 166-174, 2017
  10. Onose H., Uchida T., Sato J., Ishii S., Yamada E., Yamada T., Watada H. Monocyte and Basophil Counts as Predictors of Neutrophil Count Recovery in Patients with Thiamazole-induced Agranulocytosis. Exp Clin Endocrinol Diabetes 125(1): 49-52, 2017
  11. Ogihara T., Mita T., Osonoi Y., Osonoi T., Saito M., Tamasawa A., Nakayama S., Someya Y., Ishida H., Gosho M., Kanazawa A., Watada H. Relationships between lifestyle patterns and cardio-renal-metabolic parameters in patients with type 2 diabetes mellitus: A cross-sectional study. PLoS One 12(3): e0173540, 2017
  12. Mita T., Katakami N., Shiraiwa T., Yoshii H., Kuribayashi N., Osonoi T., Kaneto H., Kosugi K., Umayahara Y., Gosho M., Shimomura I., Watada H. Relationship between frequency of hypoglycemic episodes and changes in carotid atherosclerosis in insulin-treated patients with type 2 diabetes mellitus. Sci Rep 7: 39965, 2017
  13. Mita T., Katakami N., Shiraiwa T., Yoshii H., Gosho M., Shimomura I., Watada H., Sitagliptin Preventive Study of Intima-media Thickness Evaluation , Trial. Changes in carotid intima-media thickening in patients with type 2 diabetes mellitus: Subanalysis of the Sitagliptin Preventive Study of Intima-Media Thickness Evaluation J Diabetes Investig 8(2): 254-255, 2017
  14. Mita T., Katakami N., Shiraiwa T., Yoshii H., Gosho M., Shimomura I., Watada H. The Effect of Sitagliptin on the Regression of Carotid Intima-Media Thickening in Patients with Type 2 Diabetes Mellitus: A Post Hoc Analysis of the Sitagliptin Preventive Study of Intima-Media Thickness Evaluation. Int J Endocrinol 2017: 1925305, 2017
  15. Kuramitsu S., Miyauchi K., Yokoi H., Suwa S., Nishizaki Y., Yokoyama T., Nojiri S., Iwabuchi M., Shirai S., Ando K., Okazaki S., Tamura H., Watada H., Daida H. Effect of sitagliptin on plaque changes in coronary artery following acute coronary syndrome in diabetic patients: The ESPECIAL-ACS study. J Cardiol 69(1): 369-376, 2017
  16. Koga M., Inada S., Nakao T., Kawamori R., Kasayama S. The Glycated Albumin (GA) to HbA1c Ratio Reflects Shorter-Term Glycemic Control than GA: Analysis of Patients with Fulminant Type 1 Diabetes J Clin Lab Anal 31(1): e22023 2017
  17. Ishii H., Niiya T., Ono Y., Inaba N., Jinnouchi H., Watada H. Improvement of quality of life through glycemic control by liraglutide, a GLP-1 analog, in insulin-naive patients with type 2 diabetes mellitus: the PAGE1 study. Diabetol Metab Syndr 9: 3, 2017
  18. Hashimoto S., Nagai M., Fukuma S., Ohira T., Hosoya M., Yasumura S., Satoh H., Suzuki H., Sakai A., Ohtsuru A., Kawasaki Y., Takahashi A., Ozasa K., Kobashi G., Kamiya K., Yamashita S., Fukuhara S., Ohto H., Abe M., Fukushima Health Management Survey G. Influence of Post-disaster Evacuation on Incidence of Metabolic Syndrome. J Atheroscler Thromb 24(3): 327-337, 2017
  19. Funayama T., Tamura Y., Takeno K., Kawaguchi M., Kakehi S., Watanabe T., Furukawa Y., Kaga H., Yamamoto R., Kanazawa A., Fujitani Y., Kawamori R., Watada H. Effects of alcohol abstinence on glucose metabolism in Japanese men with elevated fasting glucose: A pilot study. Sci Rep 7: 40277, 2017
  20. Chen W., Qian L., Watada H., Li P., Iwamoto N., Imori M., Yang W. Impact of diet on the efficacy of insulin lispro mix 25 and insulin lispro mix 50 as starter insulin in East Asian patients with type 2 diabetes: Subgroup analysis of the Comparison Between Low Mixed Insulin and Mid Mixed Insulin as Starter Insulin For Patients with Type 2 Diabetes Mellitus (CLASSIFY Study) randomized trial. J Diabetes Investig 8(1): 75-83, 2017
  21. Yamaguchi H., Arakawa S., Kanaseki T., Miyatsuka T., Fujitani Y., Watada H., Tsujimoto Y., Shimizu S. Golgi membrane-associated degradation pathway in yeast and mammals EMBO J 35(18): 1991-2007, 2016
  22. Ueyama M., Nishida N., Korenaga M., Korenaga K., Kumagai E., Yanai H., Adachi H., Katsuyama H., Moriyama S., Hamasaki H., Sako A., Sugiyama M., Aoki Y., Imamura M., Murata K., Masaki N., Kawaguchi T., Torimura T., Hyogo H., Aikata H., Ito K., Sumida Y., Kanazawa A., Watada H., Okamoto K., Honda K., Kon K., Kanto T., Mizokami M., Watanabe S. The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus J Gastroenterol 51(4): 370-379, 2016
  23. Tanaka A., Inoue T., Kitakaze M., Oyama J., Sata M., Taguchi I., Shimizu W., Watada H., Tomiyama H., Ako J., Sakata Y., Anzai T., Uematsu M., Suzuki M., Eguchi K., Yamashina A., Saito Y., Sato Y., Ueda S., Murohara T., Node K. Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial Cardiovasc Diabetol 15(1): 57, 2016
  24. Takeno K., Tamura Y., Kawaguchi M., Kakehi S., Watanabe T., Funayama T., Furukawa Y., Kaga H., Yamamoto R., Kim M., Nishitani-Yokoyama M., Shimada K., Daida H., Aoki S., Taka H., Fujimura T., Sawada S., Giacca A., Kanazawa A., Fujitani Y., Kawamori R., Watada H. Relation between insulin sensitivity and metabolic abnormalities in Japanese men with BMI of 23-25 kg/m2. J Clin Endocrinol Metab 101(10): 3676-3684, 2016
  25. Schnell O., Weng J., Sheu W. H., Watada H., Kalra S., Soegondo S., Yamamoto N., Rathod R., Zhang C., Grzeszczak W. Acarbose reduces body weight irrespective of glycemic control in patients with diabetes: results of a worldwide, non-interventional, observational study data pool J Diabetes Complications 30(4): 628-37, 2016
  26. Satoh H., Ohira T., Nagai M., Hosoya M., Sakai A., Watanabe T., Ohtsuru A., Kawasaki Y., Suzuki H., Takahashi A., Kobashi G., Ozasa K., Yasumura S., Yamashita S., Kamiya K., Abe M. Hypo-high-density Lipoprotein Cholesterolemia Caused by Evacuation after the Fukushima Daiichi Nuclear Power Plant Accident: Results from the Fukushima Health Management Survey. Intern Med 55(15): 1967-1976, 2016
  27. Satoh H., Ohira T., Nagai M., Hosoya M., Sakai A., Watanabe T., Ohtsuru A., Kawasaki Y., Suzuki H., Takahashi A., Kobashi G., Ozasa K., Yasumura S., Yamashita S., Kamiya K., Abe M. Prevalence of Renal Dysfunction among Evacuees and Non-evacuees after the Great East Earthquake: Results from the Fukushima Health Management Survey. Intern Med 55(18): 2563-2569, 2016
  28. Ohira T., Hosoya M., Yasumura S., Satoh H., Suzuki H., Sakai A., Ohtsuru A., Kawasaki Y., Takahashi A., Ozasa K., Kobashi G., Kamiya K., Yamashita S., Abe M., Fukushima Health Management Survey G. Effect of Evacuation on Body Weight After the Great East Japan Earthquake. Am J Prev Med 50(5): 553-560, 2016
  29. Ohira T., Hosoya M., Yasumura S., Satoh H., Suzuki H., Sakai A., Ohtsuru A., Kawasaki Y., Takahashi A., Ozasa K., Kobashi G., Hashimoto S., Kamiya K., Yamashita S., Abe M., Fukushima Health Management Survey G. Evacuation and Risk of Hypertension After the Great East Japan Earthquake: The Fukushima Health Management Survey. Hypertension 68(3): 558-564, 2016
  30. Moriya C., Satoh H. Teneligliptin Decreases Uric Acid Levels by Reducing Xanthine Dehydrogenase Expression in White Adipose Tissue of Male Wistar Rats. J Diabetes Res 2016: 3201534, 2016
  31. Mita T., Katakami N., Shimomura I., Watada H. Response to Comment on Mita et al. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial. Diabetes Care 2016;39:455-464 Diabetes Care 39(7): e104-5, 2016
  32. Matsuba R., Imamura M., Tanaka Y., Iwata M., Hirose H., Kaku K., Maegawa H., Watada H., Tobe K., Kashiwagi A., Kawamori R., Maeda S. Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta- Analysis of Genome-Wide Association Studies. PLoS One 11(4): e0154093, 2016
  33. Ikeda S., Tamura Y., Kakehi S., Sanada H., Kawamori R., Watada H. Exercise-induced increase in IL-6 level enhances GLUT4 expression and insulin sensitivity in mouse skeletal muscle. Biochem Biophys Res Commun 473(4): 947-52, 2016
  34. Hirai H., Ogata E., Ohki S., Fukuda I., Tanaka M., Watanabe T., Satoh H. Hypoglycemia Associated with a Gastrointestinal Stromal Tumor Producing High-molecular-weight Insulin Growth Factor II: A Case Report and Literature Review. Intern Med 55(10): 1309-1314, 2016
  35. Hirai H., Ogata E., Kikuchi N., Kohno T., Machii N., Hasegawa K., Watanabe T., Satoh H. The effects of liraglutide on both hypereosinophilic insulin allergy and the characteristics of anti-insulin antibodies in type 2 diabetes mellitus: a case report. J Med Case Rep 10: 202, 2016
  36. Hirai H., Midorikawa S., Suzuki S., Sasano H., Watanabe T., Satoh H. Somatostatin-secreting Pheochromocytoma Mimicking Insulin-dependent Diabetes Mellitus. Intern Med 55(20): 2985-2991, 2016
  37. Hirai H., Fukushima N., Hasegawa K., Watanabe T., Hasegawa O., Satoh H. Superior Mesenteric Artery Syndrome Complicated by Diabetic Ketoacidosis and Graves' Disease in Slowly Progressive Insulin Dependent Diabetes Mellitus (SPIDDM): A Case Report and a Review of the Literature. Intern Med 55(15): 2035-2042, 2016
  38. Fujitani Y., Fujimoto S., Takahashi K., Satoh H., Hirose T., Hiyoshi T., Ai M., Okada Y., Gosho M., Mita T., Watada H. Effects of linagliptin monotherapy compared with voglibose on postprandial blood glucose responses in Japanese patients with type 2 diabetes: Linagliptin Study of Effects on Postprandial blood glucose (L-STEP). Diabetes Res Clin Pract 121: 146-156, 2016

2015年度

  1. Yasuda H., Hotta N., Kasuga M., Kashiwagi A., Kawamori R., Yamada T., Baba Y., Alev L., Nakajo K. Efficacy and safety of 40 mg or 60 mg duloxetine in Japanese adults with diabetic neuropathic pain: Results from a randomized, 52-week, open-label study. J Diabetes Investig 7(4): 100-108, 2016
  2. Uchida T., Suzuki R., Kasai T., Onose H., Komiya K., Goto H., Takeno K., Ishii S., Sato J., Honda A., Kawano Y., Himuro M., Yamada E., Yamada T., Watada H. Cutoff value of thyroid uptake of (99m)Tc-pertechnetate to discriminate between Graves' disease and painless thyroiditis: a single center retrospective study. Endocr J 63(2): 143-149, 2016
  3. Uchida T., Himuro M., Komiya K., Goto H., Takeno K., Honda A., Sato J., Kawano Y., Suzuki R., Watada H. Evanescent Hyperechoic Changes After Fine-Needle Aspiration Biopsy of the Thyroid in a Series With a Low Overall Prevalence of Complications Journal of Ultrasound in Medicine 35(3): 599-604, 2016
  4. Teramukai S., Okuda Y., Miyazaki S., Kawamori R., Shirayama M., Teramoto T. Dynamic prediction model and risk assessment chart for cardiovascular disease based on on-treatment blood pressure and baseline risk factors. Hypertens Res 39(2): 113-8, 2016
  5. Sato J., Kanazawa A., Ikeda F., Shigihara N., Kawaguchi M., Komiya K., Uchida T., Ogihara T., Mita T., Shimizu T., Fujitani Y., Watada H. Effect of treatment guidance using a retrospective continuous glucose monitoring system on glycaemic control in outpatients with type 2 diabetes mellitus: A randomized controlled trial. J Int Med Res 44(1): 109-121, 2016
  6. Osonoi Y., Mita T., Osonoi T., Saito M., Tamasawa A., Nakayama S., Someya Y., Ishida H., Kanazawa A., Gosho M., Fujitani Y., Watada H. Relationship between dietary patterns and risk factors for cardiovascular disease in patients with type 2 diabetes mellitus: a cross-sectional study. Nutr J 15: 15, 2016
  7. Mita T., Katakami N., Yoshii H., Onuma T., Kaneto H., Osonoi T., Shiraiwa T., Kosugi K., Umayahara Y., Yamamoto T., Yokoyama H., Kuribayashi N., Jinnouchi H., Gosho M., Shimomura I., Watada H. Collaborators on the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis, Trial. Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). Diabetes Care 39(1): 139-48, 2016
  8. Mita T., Katakami N., Shiraiwa T., Yoshii H., Onuma T., Kuribayashi N., Osonoi T., Kaneto H., Kosugi K., Umayahara Y., Yamamoto T., Matsumoto K., Yokoyama H., Tsugawa M., Gosho M., Shimomura I., Watada H. Collaborators on the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis, Trial. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial Diabetes Care 39(3): 455-64, 2016
  9. Kubo F., Miyatsuka T., Sasaki S., Takahara M., Yamamoto Y., Shimo N., Watada H., Kaneto H., Gannon M., Matsuoka T., Shimomura I. Sustained expression of GLP-1 receptor differentially modulates β-cell functions in diabetic and nondiabetic mice. Biochem Biophys Res Commun 471(1): 68-74, 2016
  10. Kakehi S., Tamura Y., Takeno K., Sakurai Y., Kawaguchi M., Watanabe T., Funayama T., Sato F., Ikeda S., Kanazawa A., Fujitani Y., Kawamori R., Watada H. Increased intramyocellular lipid/impaired insulin sensitivity is associated with altered lipid metabolic genes in muscle of high responders to a high-fat diet. Am J Physiol Endocrinol Metab 310(1): E32-40, 2016
  11. Imamura M., Takahashi A., Yamauchi T., Hara K., Yasuda K., Grarup N., Zhao W., Wang X., Huerta-Chagoya A., Hu C., Moon S., Long J., Kwak S. H., Rasheed A., Saxena R., Ma R. C., Okada Y., Iwata M., Hosoe J., Shojima N., Iwasaki M., Fujita H., Suzuki K., Danesh J., Jorgensen T., Jorgensen M. E., Witte D. R., Brandslund I., Christensen C., Hansen T., Mercader J. M., Flannick J., Moreno-Macias H., Burtt N. P., Zhang R., Kim Y. J., Zheng W., Singh J. R., Tam C. H., Hirose H., Maegawa H., Ito C., Kaku K., Watada H., Tanaka Y., Tobe K., Kawamori R., Kubo M., Cho Y. S., Chan J. C., Sanghera D., Frossard P., Park K. S., Shu X. O., Kim B. J., Florez J. C., Tusie-Luna T., Jia W., Tai E. S., Pedersen O., Saleheen D., Maeda S., Kadowaki T. Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. Nat Commun 7: 10531, 2016
  12. Foley J., Bhosekar V., Kawamori R. Does the treatment of type 2 diabetes mellitus with the DPP -4 inhibitor vildagliptin reduce HbA1c to a greater extent in Japanese patients than in Caucasian patients? Vasc Health Risk Manag 12: 9-12, 2016
  13. Weng J., Soegondo S., Schnell O., Sheu W., Grzeszczak W., Watada H., Yamamoto N., Kalra S. Efficacy of acarbose in different geographical regions of the world: analysis of a real-life database. Diabetes Metab Res Rev 31(2): 155-167, 2015
  14. Tosaka Y., Kanazawa A., Ikeda F., Iida M., Sato J., Matsumoto K., Uchida T., Tamura Y., Ogihara T., Mita T., Shimizu T., Goto H., Ohmura C., Fujitani Y., Watada H. Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study Int J Endocrinol 2015: 176261, 2015
  15. Tanimoto M., Kanazawa A., Hirose T., Yoshihara T., Kobayashi-Kimura S., Nakanishi R., Tosaka Y., Sasaki-Omote R., Kudo-Fujimaki K., Komiya K., Ikeda F., Someya Y., Mita T., Fujitani Y., Watada H. Comparison of sitagliptin with nateglinide on postprandial glucose and related hormones in drug-naive Japanese patients with type 2 diabetes mellitus: A pilot study J Diabetes Investig 6(5): 560-6, 2015
  16. Tanaka R., Yamashiro K., Okuma Y., Shimura H., Nakamura S., Ueno Y., Tanaka Y., Miyamoto N., Tomizawa Y., Nakahara T., Furukawa Y., Watada H., Kawamori R., Hattori N., Urabe T. Effects of Pioglitazone for Secondary Stroke Prevention in Patients with Impaired Glucose Tolerance and Newly Diagnosed Diabetes: The J-SPIRIT Study. J Atheroscler Thromb 22(12): 1305-1316, 2015
  17. Suzuki H., Ohira T., Takeishi Y., Hosoya M., Yasumura S., Satoh H., Kawasaki Y., Takahashi A., Sakai A., Ohtsuru A., Kobashi G., Ozasa K., Yamashita S., Kamiya K., Abe M., Fukushima Health Management Survey G. Increased prevalence of atrial fibrillation after the Great East Japan Earthquake: Results from the Fukushima Health Management Survey. Int J Cardiol 198: 102-105, 2015
  18. Shimo N., Matsuoka T. A., Miyatsuka T., Takebe S., Tochino Y., Takahara M., Kaneto H., Shimomura I. Short-term selective alleviation of glucotoxicity and lipotoxicity ameliorates the suppressed expression of key beta-cell factors under diabetic conditions Biochem Biophys Res Commun 467(4): 948-54, 2015
  19. Satoh H., Ohira T., Hosoya M., Sakai A., Watanabe T., Ohtsuru A., Kawasaki Y., Suzuki H., Takahashi A., Kobashi G., Ozasa K., Yasumura S., Yamashita S., Kamiya K., Abe M. Evacuation after the Fukushima Daiichi Nuclear Power Plant Accident Is a Cause of Diabetes: Results from the Fukushima Health Management Survey. J Diabetes Res 2015: 627390, 2015
  20. Sasaki S., Miyatsuka T., Matsuoka T., Takahara M., Yamamoto Y., Yasuda T., Kaneto H., Fujitani Y., German M., Akiyama H., Watada H., Shimomura I. Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice. Diabetologia 58(11): 2582-2591, 2015
  21. Osonoi Y., Mita T., Osonoi T., Saito M., Tamasawa A., Nakayama S., Someya Y., Ishida H., Kanazawa A., Gosho M., Fujitani Y., Watada H. Poor sleep quality is associated with increased arterial stiffness in Japanese patients with type 2 diabetes mellitus. BMC Endocr Disord 15: 29, 2015
  22. Ohmura H., Mita T., Taneda Y., Sugawara M., Funayama H., Matsuoka J., Watada H., Daida H. Efficacy and Safety of Sitagliptin in Japanese Patients With Type 2 Diabetes J Clin Med Res 7(4): 211-219, 2015
  23. Nishida Y., Rardin M., Carrico C., He W., Sahu A., Gut P., Najjar R., Fitch M., Hellerstein M., Gibson B., Verdin E. SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target. Molecular Cell 59(2): 321-32, 2015
  24. Nakajima K., Mita T., Osonoi Y., Azuma K., Takasu T., Fujitani Y., Watada H. Effect of Repetitive Glucose Spike and Hypoglycaemia on Atherosclerosis and Death Rate in Apo E-Deficient Mice. Int J Endocrinol 2015: 406394, 2015
  25. Matsuba R., Sakai K., Imamura M., Tanaka Y., Iwata M., Hirose H., Kaku K., Maegawa H., Watada H., Tobe K., Kashiwagi A., Kawamori R., Maeda S. Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes. PLoS One 10(5): e0126363, 2015
  26. Kurano M., Hara M., Satoh H., Tsukamoto K. Hepatic NPC1L1 overexpression ameliorates glucose metabolism in diabetic mice via suppression of gluconeogenesis. Metabolism 64(5): 588-596, 2015
  27. Kawata T., Daimon M., Miyazaki S., Ichikawa R., Maruyama M., Chiang S., Ito C., Sato F., Watada H., Daida H. Coronary microvascular function is independently associated with left ventricular filling pressure in patients with type 2 diabetes mellitus. Cardiovasc Diabetol 14: 98, 2015
  28. Kawasaki Y., Hosoya M., Yasumura S., Ohira T., Satoh H., Suzuki H., Sakai A., Ohtsuru A., Takahashi A., Ozasa K., Kobashi G., Kamiya K., Yamashita S., Abe M., Fukushima Health Management Survey G. he Basic Data for Residents Aged 15 Years or Younger Who Received a Comprehensive Health Check in 2011-2012 as a Part of the Fukushima Health Management Survey after the Great East Japan Earthquake. Fukushima J Med Sci 61(2): 101-110, 2015
  29. Iida H., Ogihara T., Min M., Hara A., Kim Y., Fujimaki K., Tamaki M., Fujitani Y., Kim H., Watada H. Expression mechanism of tryptophan hydroxylase 1 in mouse islets during pregnancy. Journal of molecular endocrinology 55(1): 41-53, 2015
  30. Fujimaki K., Ogihara T., Morris D., Oda H., Iida H., Fujitani Y., Mirmira R., Evans-Molina C., Watada H. SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell. J Biol Chem 290(27): 16607-16618, 2015
  31. Enomoto M., Yoshii H., Mita T., Sanke H., Yokota A., Yamashiro K., Inagaki N., Gosho M., Ohmura C., Kudo K., Watada H., Onuma T. Relationship between dietary pattern and cognitive function in elderly patients with type 2 diabetes mellitus. J Int Med Res 43(4): 506-517, 2015

【和文原著】

2018年度

  1. 佐藤淳子「腸内細菌と2型糖尿病」生物の科学 遺伝 72: 131-138, 2018
  2. 佐藤淳子「腸内細菌と糖尿病」 更年期と加齢のヘルスケア 72: 47-53, 2018
  3. 遅野井雄介, 三田智也「薬物療法:注射薬による治療②GLP-1製剤」Hospitalist 6(2): 371-379, 2018
  4. 田村好史, 加藤晴香, 黄章徳, 木佐貫幸一, 土屋志織, 寺島玄, 嶋﨑幸生「日本の2型糖尿病患者におけるメトホルミンとDPP-4阻害薬の処方実態-医療情報データベースを用いた年次推移の検討-」THERAPEUTIC RESEARCH LIFE SCIENCE PUBLISHING 39(1): 67-75, 2018

【英文総説】

2018年度

  1. Fink, J., Matsumoto, M., Tamura, Y. Potential application of testosterone replacement therapy as treatment for obesity and type 2 diabetes in men. Steroids 138: 161-166, 2018,
  2. Satoh, H. Pleiotropic effects of SGLT2 inhibitors beyond the effect on glycemic control. Diabetol Int 9(4): 212-214, 2018

【和文総説】

2018年度

  1. 加賀英義 「運動と介護原因疾患 その1:脳卒中編」糖尿病医師・医療スタッフのプラクティス 35(1): 72-75, 2018
  2. 加賀英義 「運動と介護原因疾患 その2:認知症編」糖尿病医師・医療スタッフのプラクティス 35(2): 186-188, 2018
  3. 加賀英義 「運動と介護原因疾患 その3:骨折・骨粗鬆症編」糖尿病医師・医療スタッフのプラクティス 35(3): 310-312, 2018
  4. 加賀英義, 田村好史 「運動療法」Medical Practice 35(2): 281-285, 2018
  5. 加賀英義, 田村好史 「肥満症の運動療法」内分泌・糖尿病・代謝内科 47(4): 335-340, 2018
  6. 河盛隆造 「糖尿病と睡眠障害」睡眠医療 12(1): 7-8, 2018
  7. 金澤昭雄 「2型糖尿病と腸内フローラ-プロバイオティクスによる介入の効果-」機能性食品と薬理栄養 12(1): 24-28, 2018
  8. 後藤広昌 「甲状腺疾患と2型糖尿病」DITN 478: 8, 2018
  9. 佐藤元律, 田村好史 「運動をすると、どのようにエネルギーが消費されるの?」糖尿病ケア 15(9): 780-782, 2018
  10. 佐藤元律, 田村好史, 加賀英義 「ヒト骨格筋のミトコンドリア機能とインスリン感受性」内分泌・糖尿病・代謝内科 47(5): 355-359, 2018
  11. 佐藤淳子 「腸内細菌叢と甲状腺疾患」日本甲状腺学会雑誌 9(1): 33-36, 2018
  12. 佐藤博亮 「特集 糖尿病治療のUPDATE『糖尿病治療薬の効果と選択 ~糖尿病患者の病態に応じた薬物選択~』」CLINIC magazine 45(2): 9-14, 2018
  13. 佐藤博亮 「特集2 糖尿病の合併症で初期に現れる 神経障害の進行を止め人工透析を回避!」健康365 15: 84-87, 2018
  14. 三田智也 「CVD-REAL試験」内分泌・糖尿病・代謝内科 46(4): 232-238, 2018
  15. 山崎望, 田村好史 「運動をすることで血糖値が下がるのは, エネルギーが消費されるからなの? ほかにも理由があるの?」糖尿病ケア 15(9): 783-785, 2018
  16. 常見亜佐子, 金澤昭雄, 綿田裕孝 「インスリン療法」臨牀と研究 95(1): 53-59, 2018
  17. 常見亜佐子, 綿田裕孝 「メトホルミン」Pharma Medica 36(6): 21-25, 2018
  18. 西尾理恵, 綿田裕孝 「DPP-4阻害薬の大規模臨床研究」週刊 医学のあゆみ 267(2): 131-136, 2018
  19. 遅野井雄介, 三田智也 「2型糖尿病の発症と夜型生活リズムの関連について」睡眠医療 12(1): 47-53, 2018
  20. 田村好史, 加賀英義 「骨格筋細胞内脂質蓄積とインスリン抵抗性」週刊 医学のあゆみ 266(10): 769-771, 2018
  21. 田村好史, 加賀英義, 染谷由希, 筧佐織 「治療 2.糖尿病・内分泌内科における運動療法」最新醫學 73(1): 65-70, 2018
  22. 田村好史, 加賀英義, 筧佐織 「ヒトにおける異所性脂肪蓄積の制御」実験医学 36(16): 2716-2721, 2018
  23. 内田豊義, 綿田裕孝 「バセドウ病の薬物治療-副作用の側面から-」内分泌・糖尿病・代謝内科 47(2): 72-75, 2018
  24. 内田豊義, 綿田裕孝 「日常診療で遭遇する前に知っておきたい甲状腺疾患」診断と治療 106(9): 1063-1071, 2018
  25. 氷室美和, 綿田裕孝 「長期間のGABA投与によって膵α細胞からβ細胞様細胞新生が生じる」DIABETES UPDATE 7(1): 16-17, 2018
  26. 綿田裕孝 「特集にあたって」内分泌・糖尿病・代謝内科 46(4): 217-218, 2018
  27. 綿田裕孝 「糖尿病感受性遺伝子の病態形成のメカニズムの解明-ZnT8を例として-」MSD(Medical Science Digest) 44(6): 24-26, 2018
  28. 綿田裕孝, 内田豊義 「特集にあたって」内分泌・糖尿病・代謝内科 47(2): 65-66, 2018
  29. 鈴木路可, 綿田裕孝 「アルテムエーテルは膵α細胞をβ細胞に分化転換させない」DIABETES UPDATE 7(4): 14-16, 2018

【和文著書】

2018年度

  1. 及川達也, 長尾宗彦, 木野孝一, 綿田裕孝 「2型糖尿病患者におけるレパグリニドとビグアナイド系またはチアゾリジン系薬剤との長期併用時の安全性および有効性の検討」 新薬と臨牀 医薬情報研究所 67(4): 3-42, 2018
  2. 後藤広昌 「甲状腺機能とその調節」 (編集)内田豊義  入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 8-15, 2018
  3. 佐藤淳子 「バセドウ病」 (編集)内田豊義  入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 27-31, 2018
  4. 小宮幸次 「甲状腺機能検査とその解釈」 (編集)内田豊義  入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 21-26, 2018
  5. 常見亜佐子 「抗甲状腺薬・甲状腺ホルモン薬の臨床薬理」 (編集)内田豊義   入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 73-77, 2018
  6. 増山敦 「Block and replace療法」 (編集)内田豊義  入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 39, 2018
  7. 竹野景海 「甲状腺機能異常の分類と臨床症状」 (編集)内田豊義  入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 16-20, 2018
  8. 中島健一, 三田智也 「動脈硬化症は血管内皮細胞障害をきっかけとして発症する」 (編集)坂井建雄, 石崎泰樹 人体の細胞生物学 日本医事新報社 248-249, 2018
  9. 田村好史 「序」 (編著)田村好史 今度こそできる!糖尿病運動療法 サイエンス&プラクティス 医歯薬出版株式会社 Ⅳ-Ⅴ, 2018
  10. 田村好史 「4 糖尿病患者における運動による血糖降下メカニズム」 (編著)田村好史  今度こそできる!糖尿病運動療法 サイエンス&プラクティス 医歯薬出版株式会社 27-35, 2018
  11. 田村好史 「メタボリック症候群の主役はインスリン抵抗性である」 (編集)坂井建雄, 石崎泰樹  人体の細胞生物学 日本医事新報社 244-245, 2018
  12. 登坂祐佳 「薬剤性甲状腺機能異常症」 (編集)内田豊義 入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 56-60, 2018
  13. 内田豊義 「機能性甲状腺結節」 (編集)内田豊義 入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 54-55, 2018
  14. 内田豊義, 綿田裕孝 「2. 各種薬剤との併用の実際と,可能性-配合剤の位置づけも含めて-」 (編集)稲垣暢也 SGLT2阻害薬のすべて 第2版 先端医学社 129-138, 2018
  15. 氷室美和 「破壊性甲状腺炎」 (編集)内田豊義 入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 49-53, 2018
  16. 本田彬 「バセドウ病」 (編集)内田豊義 入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 32-38, 2018
  17. 綿田裕孝 「糖尿病・内分泌、代謝の異常による病気」 家庭の医学 ― すぐわかる よくわかる 主婦の友社 512-533, 2018
  18. 綿田裕孝 「ステロイド糖尿病」 (編集)稲垣暢也, 石原寿光, 矢部大介, 綿田裕孝 DxM アルタ出版 19, 2018
  19. 綿田裕孝 「糖代謝-総論」 (編集)日本内分泌学会 内分泌代謝科専門医研修ガイドブック 診断と治療社, 588-592, 2018
  20. 綿田裕孝 「3 血糖コントロールに影響を及ぼす主な薬剤」 (編集)寺内康夫, 荒木厚 糖尿病×〇〇〇の診かた考えかた 南江堂 22-30, 2018
  21. 綿田裕孝 「インスリン分泌低下とインスリン抵抗性により糖尿病が起こる」 (編集)坂井建雄, 石崎泰樹 人体の細胞生物学 日本医事新報社 246-247, 2018
  22. 鈴木大地, 河盛隆造, 田村好史 「糖尿病医療とスポーツ行政の接点を探る」 (編著)田村好史 今度こそできる!糖尿病運動療法 サイエンス&プラクティス 医歯薬出版株式会社 ViiI-XV, 2018
  23. 鈴木瑠璃子 「橋本病」 (編集)内田豊義 入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 40-48, 2018
  24. 鈴木路可 「妊娠時,産後に起こる甲状腺機能異常」 (編集)内田豊義 入門!甲状腺疾患 臨床に役立つ解剖生理から薬物治療までの基本 南山堂 17(2): 61-65, 2018