MIYAKE Sachiko, M.D., Ph.D.

Department of Immunology

Short Biography

M.D. Tokyo Medical and Dental University
Ph.D. Juntendo University Graduate School of Medicine
Research Associate, Harvard Med. School and Brigham & Women's Hospital
Section Chief, National Institute of Neuroscience, NCNP
Professor, Department of Immunology, Juntendo University Faculty of Medicine


  • Autoimmune diseases
  • Neuroimmunology
  • Invariant T cell

Main Research Topics and Interests

  • Autoimmune diseases
  • Neuroimmunology
  • Invariant T cell

Publications (in English)

  • Original Articles: 95
  • Review Articles: 22
  • Books: 9
  • h-index: 52 (Scopus)
  • Sum of Times Cited: 8,653 (Scopus)

Recent Main Publications

  • Murayama G, Chiba A, Kuga T, Makiyama A, Yamaji K, Tamura N, Miyake S. Inhibition of mTOR suppresses IFNα production and the STING pathway in monocytes from systemic lupus erythematosus patients. Rheumatology (Oxford). 59(10):2992-3002, 2020
  • Murayama G, Chiba A, Suzuki H, Nomura A, Mizuno T, Kuga T, Nakamura S, Amano H, Hirose S, Yamaji K, Suzuki Y, Tamura N, Miyake S. A Critical Role for Mucosal-Associated Invariant T Cells as Regulators and Therapeutic Targets in Systemic Lupus Erythematosus. Front Immunol 10:2681, 2019
  • Chen T, Noto D, Hoshino Y, Mizuno M, Miyake S. Butyrate suppresses demyelination and enhances remyelination. J Neuroinflammation 16(1):165, 2019