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2019年- 研究業績

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1) Makiyama A, Chiba A, Noto D, Murayama G, Yamaji K, Tamura N, Miyake S. Expanded circulating peripheral helper T cells in systemic lupus erythematosus: association with disease activity and B cell differentiation. Rheumatology (Oxford). 2019;58(10):1861-1869.

2)Chen T, Noto D, Hoshino Y, Mizuno M, Miyake S. Butyrate suppresses demyelination and enhances remyelination. J Neuroinflammation 2019;16(1):165.

3) Matsuyama H, Isshiki T, Chiba A, Yamaguchi T, Murayama G, Akasaka Y, Eishi Y, Sakamoto S, Homma S, Miyake S. Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients. Sci Rep. 2019;9(1):13181.

4) Murayama G, Chiba A, Suzuki H, Nomura A, Mizuno T, Kuga T, Nakamura S, Amano H, Hirose S, Yamaji K, Suzuki Y, Tamura N, Miyake S. A Critical Role for Mucosal-Associated Invariant T Cells as Regulators and Therapeutic Targets in Systemic Lupus Erythematosus. Front Immunol 2019;10:2681.

5) Nomura A, Noto D, Murayama G, Chiba A, Miyake S. Unique primed status of microglia under the systemic autoimmune condition of lupus-prone mice. Arthritis Res Ther. 2019;21(1):303.

6) Konuma T, Kohara C, Watanabe E, Takahashi S, Ozawa G, Suzuki K, Mizukami M, Nagai E, Jimbo K, Kaito Y, Isobe M, Kato S, Takahashi S, Chiba A, Miyake S, Tojo A. Reconstitution of Circulating Mucosal-Associated Invariant T Cells after Allogeneic Hematopoietic Cell Transplantation: Its Association with the Riboflavin Synthetic Pathway of Gut Microbiota in Cord Blood Transplant Recipients. J Immunol. 2019;204(6):1462-1473.

7) Nakajima S, Chiba A, Makiyama A, Hayashi E, Murayama G, Yamaji K, Kobayashi S, Tamura N, Takasaki Y, Miyake S. Association of mucosal-associated invariant T cells with different disease phases of polymyalgia rheumatica. Rheumatology (Oxford). 2020;59(10):2939-2946.

8) Murayama G, Chiba A, Kuga T, Makiyama A, Yamaji K, Tamura N, Miyake S. Inhibition of mTOR suppresses IFNα production and the STING pathway in monocytes from systemic lupus erythematosus patients. Rheumatology (Oxford). 2020;59(10):2992-3002.

9) Takewaki D, Suda W, Sato W, Takayasu L, Kumar N, Kimura K, Kaga N, Mizuno T, Miyake S, Hattori M, Yamamura T. Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis. Proc Natl Acad Sci USA. 2020;117(36)22402-22412.

10) Nakajima S, Tanaka R, Yamashiro K, Chiba A, Noto D, Inaba T, Kurita N, Miyamoto N, Kuroki T, Shimura H, Ueno Y, Urabe T, Miyake S, Hattori N. Mucosal-Associated Invariant T Cells are Involved in Acute Ischemic Stroke by Regulating Neuroinflammation. J Am Heart Assoc. 2021;10(7) e018803.

11) Yoshizawa Y, Nakao T, Tsuritani K, Yamada T, Watanabe N, Chiba A, William H Robinson, Miyake S. The importance of specific citrullinated clusterin and vimentin found in a multi-coloured bead-based citrulline-peptide array system in rheumatoid arthritis. Clin Exp Rheumatol. 2021

12) Yasuda H, Mori Y, Chiba A, Bai J, Murayama G, Matsushita Y, Miyake S, Komatsu N. Resolution of One-Year Persisting COVID-19 Pneumonia and Development of Immune Thrombocytopenia in a Follicular Lymphoma Patient With Preceding Rituximab Maintenance Therapy: A follow-up Report and Literature Review of Cases With Prolonged Infections. Clin Lymphoma Myeloma Leuk. 2021;21(10) e810-e816.

13) Yasutomi Y, Chiba A, Haga K, Murayama G, Makiyama A, Kuga T, Watanabe M, Okamoto R, Nagahara A, Nagaishi T, Miyake S. Activated mucosal-associated invariant T cells have a pathogenic role in a murine model of inflammatory bowel disease. Cell Mol Gastroenterol Hepatol. 2021;13(1):81-93.

14) Hoshino Y, Noto D, Sano S, Tomizawa Y, Yokoyama K, Hattori N, Miyake S. Dysregulated B cell differentiation towards antibody-secreting cells in neuromyelitis optica spectrum disorder. J Neuroinflammation. 2022;19(1):6.

15) Nomura A, Mizuno M, Noto D, Aoyama A, Kuga T, Murayama G, Chiba A, Miyake S. Different Spatial and Temporal Roles of Monocytes and Monocyte-Derived Cells in the Pathogenesis of an Imiquimod Induced Lupus Model. Front Immunol. 2022;13:764557.

16) Bai J, Chiba A, Murayama G, Kuga T, Tamura N, Miyake S. Sex, Age, and Ethnic Background Shape Adaptive Immune Responses Induced by the SARS-CoV-2 mRNA Vaccine. Front Immunol. 2022;13:786586.

17) Ueda S, Ito J, Harada N, Harada S, Sasano H, Sandhu Y, Tanabe Y, Abe S, Shiota S, Kodama Y, Nagaoka T, Makino F, Chiba A, Akiba H, Atsuta R, Miyake S, Takahashi K. Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen. Biomolecules. 2022;12(4):518.

18) Ryota Yamagishi, Fumitaka Kamachi, Masaru Nakamura, Shota Yamazaki, Tomon-ori Kamiya, Masaki Takasugi, Yi Cheng, Yoshiki Nonaka, Yoshimi Yukawa-Muto, Le Thi Thanh Thuy, Yohsuke Harada, Tatsuya Arai, Tze Mun Loo, Shin Yoshimoto, Tatsuya Ando, Masahiro Nakajima, Hayao Taguchi, Takamasa Ishikawa, Hisaya Akiba, Sachiko Miyake, Masato Kubo, Yoichiro Iwakura, Shinji Fukuda, Wei-Yu Chen, Norifumi Kawada, Alexander Rudensky, Susumu Nakae, Eiji Hara, Naoko Ohtani. Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma. Sci Immunol.2022; 7(72): eabl7209.

19)Jie Bai , Asako Chiba , Goh Murayama , Taiga Kuga , Yoshiyuki Yahagi , Yoko Tabe , Naoto Tamura , Sachiko Miyake. Early CD4+ T cell responses induced by the BNT162b2 SARS-CoV-2 mRNA vaccine predict immunological memory. Sci Rep.2022;12(1):20376.


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