2000年以前 研究業績
2019- 2018-2016 2015-2013 2012-2010 2009-2007 2006-2004 2003-2001
1) Miyake S, Yagita H, Maruyama T, Hashimoto H, Miyasaka N
Okumura K: β1 Integrin-mediated interaction with extracellular matrix
protein regulates cytokine gene expression in synovial fluid cells of
rheumatoid arthritis patients. J Exp Med 177: 863-868, 1993
2) Maruyama T, Saito I, Miyake S,
Hashimoto H, Sato K, Yagita H, Okumura K Miyasaka N: A possible role of
two hydrophobic amino acids in antigen recognition by synovial T cells
in rheumatoid arthritis. Eur J Immunol 23:2059-2065, 1993
3) Miyake S, Sakurai T, Okumura K, Yagita H: Identification of collagen and laminin receptor integrins on murine lymphocytes. Eur J Immunol 24: 2000-2005, 1994
4) Panchamoorthy G, Fukazawa T, Miyake S,
Soltoff S, Reedquist K, Druker B, Shoelson S, Cantley L, Band H:
p120cbl is major substrate of tyrosine phosphorylation upon B cell
antigen receptor stimulation and interacts in vivo with Fyn and Syk
tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of
Phosphatidylinositol 3-kinase. J Biol Chem 271:3187-3194, 1996
5) Miyake S*,
Fukazawa T*, Band V, Band H: Tyrosine phosphorylation of Cbl upon
epidermal growth factor (EGF) stimulation and its association with EGF
receptor and downstream signaling proteins. J Biol Chem 271:14554-14559, 1996 * Eaqual contribution.
6) Lupher ML, Reedquist KA, Miyake S,
Langdon WY Band H: A novel phosphotyrosine-binding domain in the
N-terminal transforming region of Cbl interacts directly and
selectively with ZAP-70 in T cells. J Biol Chem 271:24063-24068, 1996
7) Tokano Y, Miyake S,
Kayagaki N, Nozawa K, Morimoto S, Azuma M, Yagita H, Takasaki Y,
Okumura K, Hashimoto H: Soluble Fas molecule in the serum of patients
with systemic lupus erythematosus. J Clin Immunol 16:261-265, 1996
8) Bonita D, Miyake S,
Lupher ML, Langdon WY, Band H:Phophotyrosine binding domain-dependent
upregulation of the platelet-derived growth factor receptor alpha
singaling cascade by transforming mutants of Cbl:Implications for Cbl's
function and oncogenicity. Mol Cell Biol 17:4597-4610, 1997
9) Miyake S,
Lupher ML, Andoniou CE, Lill NL, Ota A, Douillard P, Rao N, Band H:The
Cbl proto-oncogene product: From an enigmatic oncogene to center-stage
of singnal transduction. Critical Reviews on Oncogenesis 8:189-218, 1997
10) Miyake S,
Lupher ML, Druker B, Band H: The tyrosine kinase regulator Cbl enhances
the ubiquitination and degradation of the platelet derived growth
factor receptor α. Proc Natl Acad Sci USA 95:7927-7932, 1998
11) Lupher ML, Rao N, Andoniou CE, Miyake S, Band H: Cbl-mediated negative regulation of the Syk tyrosine kinase: A critical role for Cbl PTB domain binding to SykpY323. J Biol Chem 273:35273-35281, 1998
12) Lupher, ML, Andoniou CE, Bonita D, Miyake S, Band H: Molecules in Focus: The c-Cbl oncoprotein. Int J Biochem Cell Biol 30:439-444, 1998
13) Miyake S,
Mullane KP, Douillard P, Band H: Cbl-mediated negative regulation of
platelet-derived growth factor receptor-dependent cell proliferation. J Biol Chem 274:16619-16628, 1999
14) Lill NL, Douillard P, Awwad R, Ota S, Lupher ML, Miyake S,
Meissner NS, Hsu V, Band H: The evolutionarily conserved N-terminal
region of Cbl is sufficient to enhance down-regulation of the epidermal
growth factor receptor. J Biol Chem 275:367-377, 2000
15) Rosenkranz S, Ikuno Y, Leong FL, Klinghoffer RA, Miyake S,
Band H, Kazlauskas A: Src family kinases negatively regulate
platelet-derived growth factor alpha receptor-dependent signaling and
disease progression. J Biol Chem 275:9620-9627, 2000
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