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武藤剛（ムトウゴウ）

研究テーマ	室内環境リスク評価・分子疫学・産業衛生・環境疫学・社会疫学・免疫学（アレルギー膠原病）
研究業績（論文）	1. Association of community-level social capital with dementia: A multilevel nine-year longitudinal study using data from the Japan Gerontological Evaluation Study. S Fujihara, T Tsuji, A Nakagomi, Y Miyaguni, M Hanazato, G Muto, K Kondo. Soc Sci Med. 2023, in press. 2. Occupational safety and health of flexible work style. G Muto, A Nakata, D-U Park, K Yokoyama, Ind Health, 60: 293-294, 2022. 3. Relationship between occupational injury and gig work experience in Japanese workers during the COVID-19 pandemic: a cross-sectional internet survey. Y Morita, K Kandabashi, S Kajiki, H Saito, G Muto, T Tabuchi. Ind Health, 60: 360-370, 2022. 4. Mortality risk in older Japanese people based on self-reported dyslipidemia treatment and socioeconomic status: The JAGES cohort study. Katsuyama Y, Kondo K, Kojima M, Kamiji K, Ide K, Iizuka G, Muto G, Uehara T, Noda K, Ikusaka M. Prev Med Rep. 27: 101779, 2022. 5. Characteristics of COVID-19 infection clusters occurring among workers in several Asia-Pacific countries. M Tejamaya, W Phanprsit, J Kim, F-J Tsai, Go Muto, D Miller, A Reginald, N Granadillos, C Capule, M B Z Farid, Y-W Lin, J Park, R-Y Chen, K H Lee, J Park, H Hashimoto, H Kwon, C Yoon , C Padungtod, E A Safira, D-U Park. Ind Health, 60: 589-598, 2022. 6. Depressive and anxiety symptoms among Japanese cancer survivors: Japan cancer survivorship research project. M Endo, K Matsui, R Akaho, K Mitsui, Y Yan, Y Imai, Y Ueda, Go Muto, G A Deshpande, Y Terao, S Takeda, M Saito, K Hayashi, K Nishimura, T Tanigawa. BMC Cancer, 22: 134, 2022. 7. Increased Prevalence of Atopic Dermatitis in Children Aged 0-3 Years Highly Exposed to Parabens. Arafune J., Tsujiguchi H., Hara A., Shimizu Y., Hori D., Thao Thi Thu Nguyen,. Suzuki F., Hamagishi T., Yamada Y., Nakamura H., Yoshikawa T., Hayashi K., Shibata A., Fukutomi Y. , Ohya Y., Yamamoto-Hanada K., Muto G., Hirota R.,Konoshita T., Kambayashi Y., Nakamura H. Int J Environ Res Public Health. 18(21):11657, 2021. 8. Overview of legal measures for managing workplace COVID-19 infection risk in several Asia-Pacific countries. M Derek, F Tsai, J Kim, M Tejamaya, V Putri, G Muto, A Reginald, W Phanprasit, N Granadillos, M Farid, C Capule, Y Lin, J Park, R Chen, K Lee, J Park, H Hashimoto, C Yoon, C Padungtod, D Park. Saf Health Work.12(4)530-535, 2021. 9. Social participation and mortality according to company size of the longest-held job among older men in Japan: A 6-year follow-up study from the JAGES. Kanamori S, Kondo N, Takamiya T, Kikuchi H, Inoue S, Tsuji T, Kai Y, Muto G, Kondo K. J Occup Health. 2021 Jan;63(1):e12216. 10. Predictors of post-cancer diagnosis resignation among Japanese cancer survivors. Endo M, Muto G, Imai Y, Mitsui K, Nishimura K, Hayashi K. J Cancer Surviv. 2020 Apr;14(2):106-113. 11. Recurrent sick leave and resignation rates among female cancer survivors after return to work: the Japan sickness absence and return to work (J-SAR) study. Endo M, Haruyama Y, Muto G, Imai Y, Mitsui K, Mizoue T, Wada H, Kobashi G, Tanigawa T. BMC Public Health. 2019 Sep 11;19(1):1248. 12. For making a declaration of countermeasures against the falling birth rate from the Japanese Society for Hygiene: summary of discussion in the working group on academic research strategy against an aging society with low birth rate. Nomura K, Karita K, Araki A, Nishioka E, Muto G, Iwai-Shimada M, Nishikitani M, Inoue M, Tsurugano S, Kitano N, Tsuji M, Iijima S, Ueda K, Kamijima M, Yamagata Z, Sakata K, Iki M, Yanagisawa H, Kato M, Inadera H, Kokubo Y, Yokoyama K, Koizumi A, Otsuki T. Environ Health Prev Med. 24(1):14, 2019. 13. Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study. Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa T, Nakamura H, Mikami M, Morioka I, Ohya Y. Asia Pac Allergy. 2019 Jan 21;9(1):e5. 14. Harmonizing work with diseases treatment and prevention. Muto G, Yokoyama K, Endo M, Fujino Y. Ind Health. 2019;57(1):1-2. 15. Toward a Declaration to Address Japan's Aging Society with Low Birth Rate: Summary of the Japanese Society for Hygiene's Working Group on Academic Research Strategy against an Aging Society with Low Birth Rate. Nomura K, Karita K, Araki A, Nishioka E, Muto G, Iwai-Shimada M, Nishikitani M, Inoue M, Tsurugano S, Kitano N, Tsuji M, Iijima S, Ueda K, Kamijima M, Yamagata Z, Sakata K, Iki M, Yanagisawa H, Kato M, Yokoyama K, Koizumi A, Otsuki T. Environ Health Prev Med. 2019;24(1)14. 16. Triclosan-induced Alteration of Gut Microbiome and Aggravation of Asthmatic Airway Response in Aeroallergen-sensitized mice. Hirota R, Ohya Y, Yamamoto-Hanada K, FukutomiI Y, Muto G, Ngatu-Nlandu R, Nakamura T, Nakamura H. Allergy.74(5):996-999, 2019. 17. A cooperative support model for cancer therapy and employment balance: from focus-group interviews of health and business professionals. Takahashi M, Uetake C, Nakayama N, Eura A, Yamaguchi N, Kameda Y, Muto G, Endo M, Kawamata K, Fujii T, Oka H, Matsudaira K. Ind Health.57(1):40-51, 2019. 18. Toward the harmonization of work with treatment and prevention for patients with chronic respiratory failure. Wada H, Fukumoto S, Tamamura K, Muto G, Ueki J, Tanigawa T. Ind Health.57(1):84-89, 2019. 19. Durations of first and second periods of depression-induced sick leave among Japanese employees: the Japan sickness absence and return to work (J-SAR) study. Endo M, Haruyama Y, Mitsui K, Muto G, Nishiura C, Kuwahara K, Wada H, Tanigawa T. Ind Health.57(1):22-28, 2019. 20. Promoting and inhibiting factors for the use of validated dietary assessment questionnaires in health check-up counseling: from occupational health nurses and dietitians' perspective. Katagiri R, Muto G, Sasaki S. Ind Health.57(1):90-98, 2019. 21. Solutions against Declining Birthrates Confronting Japan's Aging Society by Supporting Female Workers in Harmonizing Work with Their Health and Social Issues: Fertility, Chronic Illness, and Raising Children. Muto G, Yokoyama K, Endo M. Nihon Eiseigaku Zasshi. 2018;73(2):200-209 22. Employment sustainability after return to work among Japanese stroke survivors. Endo M, Haruyama Y, Muto G, Yokoyama K, Kojimahara N, Yamaguchi N. Int Arch Occup Environ Health. 2018 Aug;91(6):717-724 23. Information exchange using a prescribed form and involvement of occupational health nurses promotes occupational physicians to collaborate with attending physicians for supporting workers with illness in Japan. Muto G, Nakamura RI, Yokoyama K, Kitamura F, Omori Y, Saito M, Endo M. Ind Health.57(1):10-21, 2019. 24. Work sustainability among male cancer survivors after returning to work.　Endo M, Haruyama Y, Muto G, Kiyohara K, Mizoue T, Kojimahara N, Yamguchi N. Journal of Epidemiology,28(2):88-93, 2018. 25. Large vessel vasculitis in elderly patients: early diagnosis and steroid-response evaluation with FDG-PET/CT and contrast-enhanced CT.　Muto G, Yamashita H, Takahashi Y, Miyata Y, Morooka M, Minamimoto R, Kubota K, Kaneko H, Kano T, Mimori A. Rheumatology International (Clinical and Experimental Investigations).(34):1545-1554, 2014. 26. TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity. Muto G, Kotani H, Kondo T, Morita R, Tsuruta S, Kobayashi T, Luche H, Fehling HJ, Walsh M, Choi Y, Yoshimura A. PLos One. 8(9):e74639. 2013. 27. A case of Sjögren’s syndrome complicated by protein-losing gastroenteropathy with unprecedented pulmonary interstitial lesions. Yamashita H, Muto G, Hachiya R, Sugiyama H, Takahashi Y, Kaneko H, Kano T, Mimori A. Mod Rheumatol. 24(5):877-9, 2014. 28. A patient with intravascular lymphoma presenting with cerebral infarction and a high serum MPO-ANCA level. Muto G, Takahashi Y, Yamashita H, Mimori A. Mod Rheumatol.21(2):207-10, 2011. 29. SOCS1 is essential for regulatory T cell functions by presenting loss of Foxp3 expression as well as IFN-gamma and IL-17A production. Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Asakawa M, Chinen T, Yoshimura A. J Exp Med. 2011 Sep 26;208(10):2055-67. 30. Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin. Ichiyama K, Sekiya T, Inoue N, Tamiya T, Kashiwagi I, Kimura A, Morita R, Muto G, Shichita T, Takahashi R, Yoshimura A. Immunity. 2011 May 27;34(5):741-54. 31. Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance. Chinen T, Komai K, Muto G, Morita R, Inoue N, Yoshida H, Sekiya T, Yoshida R, Nakamura K, Takayanagi R, Yoshimura A. Nat Commun. 2011 Feb 8;2:190. 32. Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model. Konoeda F, Shichita T, Yoshida H, Sugiyama Y, Muto G, Hasegawa E, Morita R, Suzuki N, Yoshimura A. Biochem Biophys Res Commun. 2010 Nov 19;402(3):500-6. 33. Smad2 and Smad3 are redundantly essential for the TGF-β-mediated regulation of regulatory T plasticity and Th1 development. Takimoto T, Wakabayashi Y, Sekiya T, Inoue N, Morita R, Ichiyama K, Takahashi R, Asakawa M, Muto G, Mori T, Hasegawa E, Saika S, Hara T, Nomura M, Yoshimura A. J Immunol. 2010 Jul 15;185(2):842-55. 34. TGF-β function in immune suppression. Yoshimura A, Muto G. Curr Top Microbiol Immunol. 2011;350:127-47. Review.

研究テーマ

室内環境リスク評価・分子疫学・産業衛生・環境疫学・社会疫学・免疫学（アレルギー膠原病）

研究業績（論文）

1. Association of community-level social capital with dementia: A multilevel nine-year longitudinal study using data from the Japan Gerontological Evaluation Study. S Fujihara, T Tsuji, A Nakagomi, Y Miyaguni, M Hanazato, G Muto, K Kondo. Soc Sci Med. 2023, in press.

2. Occupational safety and health of flexible work style. G Muto, A Nakata, D-U Park, K Yokoyama, Ind Health, 60: 293-294, 2022.

3. Relationship between occupational injury and gig work experience in Japanese workers during the COVID-19 pandemic: a cross-sectional internet survey. Y Morita, K Kandabashi, S Kajiki, H Saito, G Muto, T Tabuchi. Ind Health, 60: 360-370, 2022.

4. Mortality risk in older Japanese people based on self-reported dyslipidemia treatment and socioeconomic status: The JAGES cohort study. Katsuyama Y, Kondo K, Kojima M, Kamiji K, Ide K, Iizuka G, Muto G, Uehara T, Noda K, Ikusaka M. Prev Med Rep. 27: 101779, 2022.

5. Characteristics of COVID-19 infection clusters occurring among workers in several Asia-Pacific countries.
M Tejamaya, W Phanprsit, J Kim, F-J Tsai, Go Muto, D Miller, A Reginald, N Granadillos, C Capule, M B Z Farid, Y-W Lin, J Park, R-Y Chen, K H Lee, J Park, H Hashimoto, H Kwon, C Yoon , C Padungtod, E A Safira, D-U Park. Ind Health, 60: 589-598, 2022.

6. Depressive and anxiety symptoms among Japanese cancer survivors: Japan cancer survivorship research project.
M Endo, K Matsui, R Akaho, K Mitsui, Y Yan, Y Imai, Y Ueda, Go Muto, G A Deshpande, Y Terao, S Takeda, M Saito, K Hayashi, K Nishimura, T Tanigawa. BMC Cancer, 22: 134, 2022.

7. Increased Prevalence of Atopic Dermatitis in Children Aged 0-3 Years Highly Exposed to Parabens.
Arafune J., Tsujiguchi H., Hara A., Shimizu Y., Hori D., Thao Thi Thu Nguyen,. Suzuki F., Hamagishi T., Yamada Y., Nakamura H., Yoshikawa T., Hayashi K., Shibata A., Fukutomi Y. , Ohya Y., Yamamoto-Hanada K., Muto G., Hirota R.,Konoshita T., Kambayashi Y., Nakamura H. Int J Environ Res Public Health. 18(21):11657, 2021.

8. Overview of legal measures for managing workplace COVID-19 infection risk in several Asia-Pacific countries.
M Derek, F Tsai, J Kim, M Tejamaya, V Putri, G Muto, A Reginald, W Phanprasit, N Granadillos, M Farid, C Capule, Y Lin, J Park, R Chen, K Lee, J Park, H Hashimoto, C Yoon, C Padungtod, D Park. Saf Health Work.12(4)530-535, 2021.

9. Social participation and mortality according to company size of the longest-held job among older men in Japan: A 6-year follow-up study from the JAGES.
Kanamori S, Kondo N, Takamiya T, Kikuchi H, Inoue S, Tsuji T, Kai Y, Muto G, Kondo K. J Occup Health. 2021 Jan;63(1):e12216.

10. Predictors of post-cancer diagnosis resignation among Japanese cancer survivors. Endo M, Muto G, Imai Y, Mitsui K, Nishimura K, Hayashi K. J Cancer Surviv. 2020 Apr;14(2):106-113.

11. Recurrent sick leave and resignation rates among female cancer survivors after return to work: the Japan sickness absence and return to work (J-SAR) study. Endo M, Haruyama Y, Muto G, Imai Y, Mitsui K, Mizoue T, Wada H, Kobashi G, Tanigawa T. BMC Public Health. 2019 Sep 11;19(1):1248.

12. For making a declaration of countermeasures against the falling birth rate from the Japanese Society for Hygiene: summary of discussion in the working group on academic research strategy against an aging society with low birth rate. Nomura K, Karita K, Araki A, Nishioka E, Muto G, Iwai-Shimada M, Nishikitani M, Inoue M, Tsurugano S, Kitano N, Tsuji M, Iijima S, Ueda K, Kamijima M, Yamagata Z, Sakata K, Iki M, Yanagisawa H, Kato M, Inadera H, Kokubo Y, Yokoyama K, Koizumi A, Otsuki T. Environ Health Prev Med. 24(1):14, 2019.

13. Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study. Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa T, Nakamura H, Mikami M, Morioka I, Ohya Y. Asia Pac Allergy. 2019 Jan 21;9(1):e5.

14. Harmonizing work with diseases treatment and prevention. Muto G, Yokoyama K, Endo M, Fujino Y. Ind Health. 2019;57(1):1-2.

15. Toward a Declaration to Address Japan's Aging Society with Low Birth Rate: Summary of the Japanese Society for Hygiene's Working Group on Academic Research Strategy against an Aging Society with Low Birth Rate. Nomura K, Karita K, Araki A, Nishioka E, Muto G, Iwai-Shimada M, Nishikitani M, Inoue M, Tsurugano S, Kitano N, Tsuji M, Iijima S, Ueda K, Kamijima M, Yamagata Z, Sakata K, Iki M, Yanagisawa H, Kato M, Yokoyama K, Koizumi A, Otsuki T. Environ Health Prev Med. 2019;24(1)14.

16. Triclosan-induced Alteration of Gut Microbiome and Aggravation of Asthmatic Airway Response in Aeroallergen-sensitized mice. Hirota R, Ohya Y, Yamamoto-Hanada K, FukutomiI Y, Muto G, Ngatu-Nlandu R, Nakamura T, Nakamura H.
Allergy.74(5):996-999, 2019.

17. A cooperative support model for cancer therapy and employment balance: from focus-group interviews of health and business professionals. Takahashi M, Uetake C, Nakayama N, Eura A, Yamaguchi N, Kameda Y, Muto G, Endo M, Kawamata K, Fujii T, Oka H, Matsudaira K. Ind Health.57(1):40-51, 2019.

18. Toward the harmonization of work with treatment and prevention for patients with chronic respiratory failure. Wada H, Fukumoto S, Tamamura K, Muto G, Ueki J, Tanigawa T.
Ind Health.57(1):84-89, 2019.

19. Durations of first and second periods of depression-induced sick leave among Japanese employees: the Japan sickness absence and return to work (J-SAR) study. Endo M, Haruyama Y, Mitsui K, Muto G, Nishiura C, Kuwahara K, Wada H, Tanigawa T. Ind Health.57(1):22-28, 2019.

20. Promoting and inhibiting factors for the use of validated dietary assessment questionnaires in health check-up counseling: from occupational health nurses and dietitians' perspective. Katagiri R, Muto G, Sasaki S. Ind Health.57(1):90-98, 2019.

21. Solutions against Declining Birthrates Confronting Japan's Aging Society by Supporting Female Workers in Harmonizing Work with Their Health and Social Issues: Fertility, Chronic Illness, and Raising Children. Muto G, Yokoyama K, Endo M. Nihon Eiseigaku Zasshi. 2018;73(2):200-209

22. Employment sustainability after return to work among Japanese stroke survivors. Endo M, Haruyama Y, Muto G, Yokoyama K, Kojimahara N, Yamaguchi N. Int Arch Occup Environ Health. 2018 Aug;91(6):717-724

23. Information exchange using a prescribed form and involvement of occupational health nurses promotes occupational physicians to collaborate with attending physicians for supporting workers with illness in Japan. Muto G, Nakamura RI, Yokoyama K, Kitamura F, Omori Y, Saito M, Endo M. Ind Health.57(1):10-21, 2019.

24. Work sustainability among male cancer survivors after returning to work.　Endo M, Haruyama Y, Muto G, Kiyohara K, Mizoue T, Kojimahara N, Yamguchi N. Journal of Epidemiology,28(2):88-93, 2018.

25. Large vessel vasculitis in elderly patients: early diagnosis and steroid-response evaluation with FDG-PET/CT and contrast-enhanced CT.　Muto G, Yamashita H, Takahashi Y, Miyata Y, Morooka M, Minamimoto R, Kubota K, Kaneko H, Kano T, Mimori A. Rheumatology International (Clinical and Experimental Investigations).(34):1545-1554, 2014.

26. TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity. Muto G, Kotani H, Kondo T, Morita R, Tsuruta S, Kobayashi T, Luche H, Fehling HJ, Walsh M, Choi Y, Yoshimura A. PLos One. 8(9):e74639. 2013.

27. A case of Sjögren’s syndrome complicated by protein-losing gastroenteropathy with unprecedented pulmonary interstitial lesions. Yamashita H, Muto G, Hachiya R, Sugiyama H, Takahashi Y, Kaneko H, Kano T, Mimori A. Mod Rheumatol. 24(5):877-9, 2014.

28. A patient with intravascular lymphoma presenting with cerebral infarction and a high serum MPO-ANCA level. Muto G, Takahashi Y, Yamashita H, Mimori A. Mod Rheumatol.21(2):207-10, 2011.

29. SOCS1 is essential for regulatory T cell functions by presenting loss of Foxp3 expression as well as IFN-gamma and IL-17A production. Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Asakawa M, Chinen T, Yoshimura A. J Exp Med. 2011 Sep 26;208(10):2055-67.

30. Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin. Ichiyama K, Sekiya T, Inoue N, Tamiya T, Kashiwagi I, Kimura A, Morita R, Muto G, Shichita T, Takahashi R, Yoshimura A. Immunity. 2011 May 27;34(5):741-54.

31. Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance. Chinen T, Komai K, Muto G, Morita R, Inoue N, Yoshida H, Sekiya T, Yoshida R, Nakamura K, Takayanagi R, Yoshimura A. Nat Commun. 2011 Feb 8;2:190.

32. Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model. Konoeda F, Shichita T, Yoshida H, Sugiyama Y, Muto G, Hasegawa E, Morita R, Suzuki N, Yoshimura A. Biochem Biophys Res Commun. 2010 Nov 19;402(3):500-6.

33. Smad2 and Smad3 are redundantly essential for the TGF-β-mediated regulation of regulatory T plasticity and Th1 development. Takimoto T, Wakabayashi Y, Sekiya T, Inoue N, Morita R, Ichiyama K, Takahashi R, Asakawa M, Muto G, Mori T, Hasegawa E, Saika S, Hara T, Nomura M, Yoshimura A. J Immunol. 2010 Jul 15;185(2):842-55.

34. TGF-β function in immune suppression. Yoshimura A, Muto G. Curr Top Microbiol Immunol. 2011;350:127-47. Review.

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研究業績詳細

武藤 剛（ムトウ ゴウ）

武藤剛（ムトウゴウ）