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研究業績詳細
蔭山 俊（カゲヤマ シュン）
| 研究テーマ | オートファジー、ユビキチン・プロテアソーム |
|---|---|
| 研究業績（論文） | 1. Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size. Shun-Suke Sakai, Atsushi Hasegawa, Ryosuke Ishimura, Naoki Tamura, Shun Kageyama, Satoko Komatsu-Hirota, Manabu Abe, Yiwei Ling, Shujiro Okuda, Manabu Funayama, Mika Kikkawa, Yoshiki Miura, Kenji Sakimura, Ichiei Narita, Satoshi Waguri, Ritsuko Shimizu, Masaaki Komatsu Molecular and cellular biology 42(1) e0002421 2022年1月20日 2. Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity. Mohammad Omar Faruk, Yoshinobu Ichimura, Shun Kageyama, Satoko Komatsu-Hirota, Afnan H El-Gowily, Yu-Shin Sou, Masato Koike, Nobuo N Noda, Masaaki Komatsu The Journal of biological chemistry 297(6) 101405-101405 2021年12月 3. BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma. Toshiyuki Nagata, Kentaro Minami, Masatatsu Yamamoto, Tsubasa Hiraki, Masashi Idogawa, Katsumi Fujimoto, Shun Kageyama, Kazuhiro Tabata, Kohichi Kawahara, Kazuhiro Ueda, Ryuji Ikeda, Yukio Kato, Masaaki Komatsu, Akihide Tanimoto, Tatsuhiko Furukawa, Masami Sato International journal of molecular sciences 22(21) 2021年10月26日 4. Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis. Tatsuro Maruyama, Jahangir Md Alam, Tomoyuki Fukuda, Shun Kageyama, Hiromi Kirisako, Yuki Ishii, Ichio Shimada, Yoshinori Ohsumi, Masaaki Komatsu, Tomotake Kanki, Hitoshi Nakatogawa, Nobuo N Noda Nature structural & molecular biology 28(7) 583-593 2021年7月 5. p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control. Eeva-Liisa Eskelinen, Shun Kageyama, Masaaki Komatsu Molecular & cellular oncology 8(2) 1890990-1890990 2021年3月9日 p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response. Shun Kageyama, Sigurdur Runar Gudmundsson, Yu-Shin Sou, Yoshinobu Ichimura, Naoki Tamura, Saiko Kazuno, Takashi Ueno, Yoshiki Miura, Daisuke Noshiro, Manabu Abe, Tsunehiro Mizushima, Nobuaki Miura, Shujiro Okuda, Hozumi Motohashi, Jin-A Lee, Kenji Sakimura, Tomoyuki Ohe, Nobuo N Noda, Satoshi Waguri, Eeva-Liisa Eskelinen, Masaaki Komatsu Nature communications 12(1) 16-16 2021年1月4日 6. Autophagic receptor p62 protects against glycation-derived toxicity and enhances viability. Gemma Aragonès, Kalavathi Dasuri, Opeoluwa Olukorede, Sarah G Francisco, Carol Renneburg, Caroline Kumsta, Malene Hansen, Shun Kageyama, Masaaki Komatsu, Sheldon Rowan, Jonathan Volkin, Michael Workman, Wenxin Yang, Paula Daza, Diego Ruano, Helena Dominguez-Martín, José Antonio Rodríguez-Navarro, Xue-Liang Du, Michael A Brownlee, Eloy Bejarano, Allen Taylor Aging cell 19(11) e13257 2020年11月 7. NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system. Pablo Sánchez-Martín, Yu-Shin Sou, Shun Kageyama, Masato Koike, Satoshi Waguri, Masaaki Komatsu EMBO reports 21(3) e48902 2020年3月4日 8. Hyperosmotic Stress Induces Unconventional Autophagy Independent of the Ulk1 Complex. Naoki Tamura, Shun Kageyama, Masaaki Komatsu, Satoshi Waguri Molecular and cellular biology 39(16) 2019年8月15日 9. Deletion of exons encoding carboxypeptidase domain of Nna1 results in Purkinje cell degeneration (pcd) phenotype. Li Zhou, M Ibrahim Hossain, Maya Yamazaki, Manabu Abe, Rie Natsume, Kohtaro Konno, Shun Kageyama, Masaaki Komatsu, Masahiko Watanabe, Kenji Sakimura, Hirohide Takebayashi Journal of neurochemistry 147(4) 557-572 2018年11月 10. Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant. Shun Kageyama, Tetsuya Saito, Miki Obata, Ryo-Hei Koide, Yoshinobu Ichimura, Masaaki Komatsu Molecular and cellular biology 38(7) 2018年4月1日 11. A novel approach to assess the ubiquitin-fold modifier 1-system in cells. Ryosuke Ishimura, Miki Obata, Shun Kageyama, Jens Daniel, Keiji Tanaka, Masaaki Komatsu FEBS letters 591(1) 196-204 2017年1月 12. Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma. Xulu Ye, Qiliang Zhou, Yoshifumi Matsumoto, Masato Moriyama, Shun Kageyama, Masaaki Komatsu, Seijiro Satoh, Masanori Tsuchida, Yasuo Saijo Anticancer research 36(11) 6021-6029 2016年11月 13. Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease. Shoji Kuwahara, Michihiro Hosojima, Reika Kaneko, Hiroyuki Aoki, Daisuke Nakano, Taiji Sasagawa, Hideyuki Kabasawa, Ryohei Kaseda, Ryota Yasukawa, Tomomi Ishikawa, Akiyo Suzuki, Hiroyoshi Sato, Shun Kageyama, Takahiro Tanaka, Nobutaka Kitamura, Ichiei Narita, Masaaki Komatsu, Akira Nishiyama, Akihiko Saito Journal of the American Society of Nephrology : JASN 27(7) 1996-2008 2016年7月 14. Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. Atsushi Eino, Shun Kageyama, Takefumi Uemura, Hiromichi Annoh, Tetsuya Saito, Ichiei Narita, Satoshi Waguri, Masaaki Komatsu Journal of cell science 128(23) 4453-61 2015年12月1日 15. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Daichi Morimoto, Erik Walinda, Harumi Fukada, Yu-Shin Sou, Shun Kageyama, Masaru Hoshino, Takashi Fujii, Hikaru Tsuchiya, Yasushi Saeki, Kyohei Arita, Mariko Ariyoshi, Hidehito Tochio, Kazuhiro Iwai, Keiichi Namba, Masaaki Komatsu, Keiji Tanaka, Masahiro Shirakawa Nature communications 6 6116-6116 2015年1月20日 16. Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway. Shun Kageyama, Yu-shin Sou, Takefumi Uemura, Satoshi Kametaka, Tetsuya Saito, Ryosuke Ishimura, Tsuguka Kouno, Lynn Bedford, R John Mayer, Myung-Shik Lee, Masayuki Yamamoto, Satoshi Waguri, Keiji Tanaka, Masaaki Komatsu The Journal of biological chemistry 289(36) 24944-55 2014年9月5日 17. Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures. Alf Håkon Lystad, Yoshinobu Ichimura, Kenji Takagi, Yinjie Yang, Serhiy Pankiv, Yumi Kanegae, Shun Kageyama, Mariko Suzuki, Izumu Saito, Tsunehiro Mizushima, Masaaki Komatsu, Anne Simonsen EMBO reports 15(5) 557-65 2014年5月 18. LC3B is indispensable for selective autophagy of p62 but not basal autophagy. Yoko Maruyama, Yu-Shin Sou, Shun Kageyama, Takao Takahashi, Takashi Ueno, Keiji Tanaka, Masaaki Komatsu, Yoshinobu Ichimura Biochemical and biophysical research communications 446(1) 309-15 2014年3月28日 19. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Yoshinobu Ichimura, Satoshi Waguri, Yu-Shin Sou, Shun Kageyama, Jun Hasegawa, Ryosuke Ishimura, Tetsuya Saito, Yinjie Yang, Tsuguka Kouno, Toshiaki Fukutomi, Takayuki Hoshii, Atsushi Hirao, Kenji Takagi, Tsunehiro Mizushima, Hozumi Motohashi, Myung-Shik Lee, Tamotsu Yoshimori, Keiji Tanaka, Masayuki Yamamoto, Masaaki Komatsu Molecular cell 51(5) 618-31 2013年9月12日 20. p62/SQSTM1/A170: physiology and pathology. Masaaki Komatsu, Shun Kageyama, Yoshinobu Ichimura Pharmacological research 66(6) 457-62 2012年12月 21. Impaired G1-arrest, autophagy, and apoptosis in Atg7-knockout mice. Shun Kageyama, Masaaki Komatsu Circulation research 111(8) 962-4 2012年9月28日 22. Three-Axis Model for Atg Recruitment in Autophagy against Salmonella. Takeshi Noda, Shun Kageyama, Naonobu Fujita, Tamotsu Yoshimori International journal of cell biology 2012 389562-389562 2012年 23. The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella. Shun Kageyama, Hiroko Omori, Tatsuya Saitoh, Takefumi Sone, Jun-Lin Guan, Shizuo Akira, Fumio Imamoto, Takeshi Noda, Tamotsu Yoshimori Molecular biology of the cell 22(13) 2290-300 2011年7月1日 24. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Tatsuya Saitoh, Naonobu Fujita, Takuya Hayashi, Keigo Takahara, Takashi Satoh, Hanna Lee, Kohichi Matsunaga, Shun Kageyama, Hiroko Omori, Takeshi Noda, Naoki Yamamoto, Taro Kawai, Ken Ishii, Osamu Takeuchi, Tamotsu Yoshimori, Shizuo Akira Proceedings of the National Academy of Sciences of the United States of America 106(49) 20842-6 2009年12月8日 25. Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts. Naonobu Fujita, Tatsuya Saitoh, Shun Kageyama, Shizuo Akira, Takeshi Noda, Tamotsu Yoshimori The Journal of biological chemistry 284(47) 32602-9 2009年11月20日 |
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