2011 Publication

1. Mizushima N, Komatsu M.
   Autophagy: renovation of cells and tissues.
   Cell. vol. 147, 728-741. Review
2. Isogai S, Morimoto D, Arita K, Unzai S, Tenno T, Hasegawa J, Sou YS, Komatsu M, Tanaka K, Shirakawa M, Tochio H.
   Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin.
   J Biol Chem. vol. 286.31864-31874
3. Komatsu M.
   Potential role of p62 in tumor development.
   Autophagy. vol. 7. 1088-1090
4. Ezaki J, Matsumoto N, Takeda-Ezaki M, Komatsu M, Takahashi K, Hiraoka Y, Taka H, Fujimura T, Takehana K, Yoshida M, Iwata J, Tanida I, Furuya N, Zheng DM, Tada N, Tanaka K, Kominami E, Ueno T.
   Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.
   Autophagy.7.727-736
5. Asano T, Komatsu M, Yamaguchi-Iwai Y, Ishikawa F, Mizushima N, Iwai K.
   Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells.
   Mol Cell Biol. 10.2040-2052
6. Ch'en IL, Tsau JS, Molkentin JD, Komatsu M, Hedrick SM.
   Mechanisms of necroptosis in T cells.
   J Exp Med. 208.633-641
7. Ushio H, Ueno T, Kojima Y, Komatsu M, Tanaka S, Yamamoto A, Ichimura Y, Ezaki J, Nishida K, Komazawa-Sakon S, Niyonsaba F, Ishii T, Yanagawa T, Kominami E, Ogawa H, Okumura K, Nakano H.
   Crucial role for autophagy in degranulation of mast cells.
   J Allergy Clin Immunol. 127.1267-1276.e6
8. Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M.
   Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
   J Cell Biol. vol 18 275-284.
9. Takamura A, Komatsu M, Hara T, Sakamoto A, Kishi C, Waguri S, Eishi Y, Hino O, Tanaka K, Mizushima N.
   Autophagy-deficient mice develop multiple liver tumors.
   Genes Dev. vol 15. 795-800.
10. Cheng HC, Kim SR, Oo TF, Kareva T, Yarygina O, Rzhetskaya M, Wang C, During M, Talloczy Z, Tanaka K, Komatsu M, Kobayashi K, Okano H, Kholodilov N, Burke RE.
    Akt suppresses retrograde degeneration of dopaminergic axons by inhibiton of macroatuophagy.
    J Neurosci.vol. 31, 2125-2135.
11. Ha BH, Jeon YJ, Shin SC, Tatsumi K, Komatsu M, Tanaka K, Watson CM, Wallis G, Chung CH, Kim EE.
    Structure of ubiquitin-fold modifier 1-specific protease UfSP2.
    J Biol Chem.vol. 286, 10248-10257.
12. Fujishima Y, Nishiumi S, Masuda A, Inoue J, Nguyen NM, Irino Y, Komatsu M, Tanaka K, Kutsumi H, Azuma T, Yoshida M.
    Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation.
    Arch Biochem Biophys. vol 506. 223-235.
13. Pei Y, Chen ZP, Ju HQ, Komatsu M, Ji YH, Liu G, Guo CW, Zhang YJ, Yang CR, Wang YF, Kitazato K.
    Autophagy is involved in anti-viral activity of pentagalloylglucose (PGG) against Herpes simplex virus type 1 infection in vitro.
    Biochem Biophys Res Commun. vol 405, 186-191.
14. Tatsumi K, Yamamoto-Mukai H, Shimizu R, Waguri S, Sou YS, Sakamoto A, Taya C, Shitara H, Hara T, Chung CH, Tanaka K, Yamamoto M, Komatsu M.
    The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.
    Nat Commn. vol. 181.
15. Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M.
    Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.
    Biochem Biophys Res Commun. vol 405, 13-18.
16. Ichimura Y, Komatsu M.
    Pathophysiological role of autophagy: lesson from autophagy-deficient mouse models.
    Exp Anim. vol 60. 329-345.

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