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Ito C, Saito Y, Nozawa T, Fujii S, Sawa T, Inoue H, Matsunaga T, Khan S, Akashi S, Hashimoto R, Aikawa C, Takahashi E, Sagara H, Komatsu M, Tanaka K, Akaike T, Nakagawa I, Arimoto H.
Mol. Cell. 52:794-804.
Endogenous nitrated nucleotide is a key mediator of autophagy and innate defense against bacteria. -
Torisu T, Torisu K, Lee IH, Liu J, Malide D, Combs CA, Wu XS, Rovira II, Fergusson MM, Weigert R, Connelly PS, Daniels MP, Komatsu M, Cao L, Finkel T.
Nat Med. 19:1281-1287.
Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor. -
Bonilla DL, Bhattacharya A, Sha Y, Xu Y, Xiang Q, Kan A, Jagannath C, Komatsu M, Eissa NT.
Immunity. 39:534-547.
Autophagy Regulates Phagocytosis by Modulating the Expression of Scavenger Receptors. -
Ichimura Y, Waguri S, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, Hoshii T, Hirao A, Takagi K, Mizushima T, Motohashi H, Lee MS, Yoshimori T, Tanaka K, Yamamoto M, Komatsu M.
Mol. Cell. 51:618-632.
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy. -
Czaja MJ, Ding WX, Donohue TM, Friedman SL, Kim JS, Komatsu M, Lemasters JJ, Lemoine A, Lin JD, Ou JH, Perlmutter DH, Randall G, RayRB, Tsung A, Yin XM.
Autophagy. 9:1131-1158.
Functions of autophagy in normal and diseased liver. -
Onal M, Piemontese M, Xiong J, Wang Y, Han L, Ye S, Komatsu M, Selig M, Weinstein RS, Zhao H, Jilka RL, Almeida M, Manolagas SC, O'Brien CA.
J Biol Chem. 288:17432-17440.
Suppression of autophagy in osteocytes mimics skeletal aging. -
Maeda H, Nagai H, Takemura G, Shintani-Ishida K, Komatsu M, Ogura S, Aki T, Shirai M, Kuwahira I, Yoshida K.
Biochim Biophys Acta. 1832:1159-1166.
Intermittent-hypoxia induced autophagy attenuates contractile dysfunction and myocardial injury in rat heart. -
Komatsu M, Kuma A, Okamoto K.
EMBO Rep. 14:219-221.
No ATG is an island--the connection of autophagy with diverse pathways and functions. -
Kim KH, Jeong YT, Oh H, Kim SH, Cho JM, Kim YN, Kim SS, Kim do H, Hur KY, Kim HK, Ko T, Han J, Kim HL, Kim J, Back SH, Komatsu M, Chen H, Chan DC, Konishi M, Itoh N, Choi CS, Lee MS.
Nat Med. 19:83-92.
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine.