2026

Mao G, Ito S, Ishimura R, Sakamaki J, Sasaki R, Uemura T, Ishikawa K, Komatsu-Hirota S, Akamatsu W, Abe M, Waguri S, Bijarnia-Mahay S, Noda NN, Inada T, Komatsu M.
The UFSP2-ODR4 complex spatially confines and dynamically controls UFM1 deconjugation to safeguard neuronal proteostasis
Molecular Cell. 2026. https://doi.org/10.1016/j.molcel.2026.06.026
Komatsu-Hirota S, Tabata K, Sou YS, Kakuta S, Sakamaki JI, Tsuchiya H, Li J, Kumeta H, Sakai Y, Fujioka Y, Noshiro D, Shimobayashi SF, Kurimura T, Taniguchi T, Abe M, Koike M, Morishita H, Noda NN, Komatsu M.
Phosphorylation tunes p62 condensates to drive autophagic degradation of ubiquitinated proteins
The EMBO J. 2026. https://doi.org/10.1038/s44318-026-00785-1
Yuen M, Zhang K, Marchant RG, Ishimura R, Graham M, Aung-Htut M, Bryen S, Rius R, Marshall L, Aryamanesh N, Dziaduch G, Joshi H, Weisburd B, Wilton SD, Wilson M, Gear R, Hennington L, Lau S, Doyle H, Krivanek M, Leventer RJ, White SM, Sandaradura SA, Komatsu M, Evesson FJ, Cooper ST.
A severe neurodevelopmental syndrome linked to a South Asian founder variant in the UFMylation adaptor CDK5RAP3
Acta Neuropathol. 2026. https://doi.org/10.1007/s00401-026-03017-2
Komatsu M, Noda NN, Inada T.
The mechanistic basis and cellular functions of UFMylation
Nat Rev Mol Cell Biol. 2026. https://doi.org/10.1038/s41580-025-00944-y