2018年 研究業績

洋雑誌

1. Sánchez-Martín P, Saito T, Komatsu M.
   p62/SQSTM1: 'Jack of all trades' in health and cancer.

   FEBS J. 2018 Nov 30. doi: 10.1111/febs.14712.

2. Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M, Zhang L, Iwakura Y, Nawa H, Higuchi M, Komatsu M, Fujii M.
   USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis.

   iScience. 2018 Nov 30;9:433-450. doi: 10.1016/j.isci.2018.11.006.

3. Sánchez-Martín P, Komatsu M.
   p62/SQSTM1 - steering the cell through health and disease.

   J Cell Sci. 2018 Nov 5;131(21). pii: jcs222836. doi: 10.1242/jcs.222836.

4. Zhou L, Hossain MI, Yamazaki M, Abe M, Natsume R, Konno K, Kageyama S, Komatsu M, Watanabe M, Sakimura K, Takebayashi H.
   Deletion of exons encoding carboxypeptidase domain of Nna1 results in Purkinje cell degeneration (pcd) phenotype.

   J Neurochem. 2018 Nov;147(4):557-572

5. Ichimura Y, Komatsu M.
   Activation of p62/SQSTM1-Keap1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Cancer.

   Front Oncol. 2018 Jun 7;8:210. doi: 10.3389/fonc.2018.00210. eCollection 2018.

6. Nahorski MS, Maddirevula S, Ishimura R, Alsahli S, Brady AF, Begemann A, Mizushima T, Guzmán-Vega FJ, Obata M, Ichimura Y, Alsaif HS, Anazi S, Ibrahim N, Abdulwahab F, Hashem M, Monies D, Abouelhoda M, Meyer BF, Alfadhel M, Eyaid W, Zweier M, Steindl K, Rauch A, Arold ST, Woods CG, Komatsu M, Alkuraya FS.
   Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development.

   Brain. 2018 Jul 1;141(7):1934-1945

7. Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.
   PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.

   Cancer Cell. 2018 Mar 12;33(3):355-367

8. Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, Nielsen R, Komatsu M, Nejsum LN, Jakobsen MR, Gyrd-Hansen M, Paludan SR.
   Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.

   EMBO J. 2018 Apr 13;37(8):e97858

9. Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsui M, Inagaki H, Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM, Yamamoto T, Imai Y, Kuba K.
   The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.

   Sci Signal. 2018 Feb 6;11(516):eaan3638

10. Sato S, Uchihara T, Fukuda T, Noda S, Kondo H, Saiki S, Komatsu M, Uchiyama Y, Tanaka K, Hattori N.
    Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice.

    Sci Rep. 2018 Feb 12;8(1):2813

11. Tamura R, Yoshihara K, Saito T, Ishimura R, Martínez-Ledesma JE, Xin H, Ishiguro T, Mori Y, Yamawaki K, Suda K, Sato S, Itamochi H, Motoyama T, Aoki Y, Okuda S, Casingal CR, Nakaoka H, Inoue I, Verhaak RGW, Komatsu M, Enomoto T.
    Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions.

    Oncogenesis. 2018 Jan 23;7(1):4

12. Kageyama S, Saito T, Obata M, Koide RH, Ichimura Y, Komatsu M.
    Negative regulation of the Keap1-Nrf2 pathway by a p62/Sqstm1 splicing variant.

    Mol Cell Biol. 2018 Jan 16;38(7):e00642-17

13. Mizunoe Y, Kobayashi M, Sudo Y, Watanabe S, Yasukawa H, Natori D, Hoshino A, Negishi A, Okita N, Komatsu M, Higami Y.
    Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways.

    Redox Biol. 2018 May;15:115-124

年度別一覧へ戻る