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Atopy Research Center
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MAY.10,2011 updated
  1. Takamura T, Harama D, Fukumoto S, Nakamura Y, Shimokawa N, Ishimaru K, Ikegami S, Makino S, Kitamura M, Nakao A: Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis. Immunol Cell Biol, in press
  2. Ebihara N, Ohtomo K, Tokura T, Ushio H, Murakami A: Effect of Tacrolimus on Chemokine Production by Corneal Myofibroblasts via Toll-Like Receptors, Compared With Cyclosporine and Dexamethasone. Cornea, in press
  3. Nishida C, Tomita T, Nishiyama M, Suzuki R, Hara M, Itoh Y, Ogawa H, Okumura K, Nishiyama C: B-transferase with Pro234Ser substitution acquires AB-transferase activity. Biosci Biotechnol Biochem, in press
  4. Potaczek DP, Nastalek M, Okumura K, Wojas-Pelc A, Undas A, Nishiyama C: An association of TLR2-16934A>T polymorphism and severity/phenotype of atopic dermatitis. J. Eur. Acad. Deramatol. Venereol, in press
  5. Suzuki K, Kaminuma O, Yang L, Takai T, Mori A, Umezu-Goto M, Ohtomo T, Ohmachi Y, Noda Y, Hirose S, Okumura K, Ogawa H, Takada K, Hirasawa M, Hiroi T, Takaiwa F: Prevention of allergic asthma by vaccination with transgenic rice seed expressing mite allergen: induction of allergen-specific oral tolerance without bystander suppression. Plant Biotechnol J, in-press
  6. Kanada S, Nishiyama C, Nakano N, Suzuki R, Maeda K, Hara M, Kitamura N, Ogawa H, Okumura K: Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells. Blood, 117:2211-2222, 2011
  7. Ushio H, Ueno T, Kojima Y, Komatsu M, Tanaka S, Yamamoto A, Ichimura Y, Ezaki J, Nishida K, Komazawa-Sakon S, Niyonsaba F, Ishii T, Yanagawa T, Kominami E, Ogawa H, Okumura K, Nakano H: Crucial role for autophagy in degranulation of mast cells. J Allergy Clin Immunol, 127:1267-1276, 2011
  8. Nakamura Y, Harama D, Shimokawa N, Hara M, Suzuki R, Tahara Y, Ishimaru K, Katoh R, Okumura K, Ogawa H, Shibata S, Nakao A: Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutanenous anaphylactic reaction. J Allergy Clin Immunol, 127:1038-1045, 2011
  9. Nakano N, Nishiyama C, Yagita H, Koyanagi A, Ogawa H, Okumura K: Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells. J Biol Chem, 286:12042-12048, 2011
  10. Nakano H, Ushio H: An unexpected role for autophagy in degranulation of mast cells. Autophagy. 7:657-659, 2011
  11. Aung G, Niyonsaba F, Ushio H, Kajiwara N, Saito H, Ikeda S, Ogawa H, Okumura K: Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. Immunology, 132:527-539, 2011
  12. Potaczek DP, Nastalek M, Wajas-Pelc A, Okumura K, Undas A, Nishiyama C: Naturally occurring FCER1A N222K mutation - its ethnicity-dependent distribution and a role in atopic dermatitis. Mol Immunol, 48:979-980, 2011
  13. Le TA, Takai T, Vu AT, Kinoshita H, Chen X, Ikeda S, Ogawa H, Okumura K: Flagellin induces the expression of thymic stromal lymphopoietin in human keratinocytes via Toll-like receptor 5. Int Arch Allergy Immunol, 155:31-37, 2011
  14. Takai T: Missions of protease allergens in the epithelium. Int Arch Allergy Immunol 154:3-5, 2011
  15. Takai T, Ikeda S: Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases. Allergol Int, 60:25-35, 2011
  16. Kawasaki J, Ushio H, Kinoshita H, Fukai T, Niyonsaba F, Takai T, Ogawa H, Okumura K, Ikeda S: Viral infection induces Thymic stromal lymphopoietin (TSLP) in human keratinocyte. J Dermatol Sci. 62:131-134, 2011
  17. Aung G, Niyonsaba F, Ushio H, Hoq MI, Ikeda S, Ogawa H, Okumura K: A neuroendocrine antimicrobial peptide, catestatin, stimulates interleukin-8 production from human keratinocytes via activation of mitogen-activated protein kinases. J Dermatol Sci, 61:142-144, 2011
  18. Potaczek D, Pieculewicz M, Mazur M, Branicka A, Nishiyama C, Okumura K, Undas A: Very rare minor homozygous GG genotype of tissue factor +5466A>G mutation in a patient with two cryptogenic cerebovascular ischemic events. Int J Cardiology, 147:e13-15, 2011
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  1. Oboki K, Ohno T, Kajiwara K, Arae K, Morita H, Ishii A, Nambu A, Abe T, Kiyonari H, Sudo K, Okumura K, Saito H, Nakae S: IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci USA, 26:18581-18586, 2010
  2. Ohki M, Ohki Y, Ishihara M, Nishida C, Tashiro Y, Akiyama H, Komiyama H, Lund LR, Nitta A, Yamada K, Zhu Z, Ogawa H, Yagita H, Okumura K, Nakauchi H, Werb Z, Heissig B, Hattori K: Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. Blood, 115:4302-4312, 2010.
  3. Vu AT, Baba T, Chen X, Le TA, Kinoshita H, Xie Y, Kamijo S, Hiramatsu K, Ikeda S, Ogawa H, Okumura K, Takai T: Staphylococcus aureus membrene and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes via the Toll-like receptor 2-Toll-like receptor 6 pathway. J Allergy Clin Immunol, 126:985-993.e1-3, 2010
  4. Maeda K, Nishiyama C, Ogawa H, Okumura K: GATA2 and Sp1 positively regulate the c-kit promoter in mast cells. J Immunol, 185:4252-4260, 2010
  5. Niyonsaba F, Ushio H, Hara M, Yokoi H, Tominaga M, Takamori K, Kajiwara N, Saito H, Nagaoka I, Ogawa H, Okumura K: Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol, 184:3526-3534, 2010
  6. Wang Q-h, Nishiyama C, Nakano N, Kanada S, Hara M, Kitamura N, Shimokawa N, Lu C-l, Ogawa H, Okumura K: Opposite effects of Trichostatin A on activation of mast cells by different stimulants. FEBS Lett, 584:2315-2320, 2010
  7. Takenaka H, Ushio H, Niyonsaba F, Jayawardana ST, Hajime S, Ikeda S, Ogawa H, Okumura K: Synergistic augmentation of inflammatory cytokine productions from murine mast cells by monomeric IgE and toll-like receptor ligands. Biochem Biophys Res Commun, 391:471-476, 2010
  8. Hirasawa Y, Takai T, Nakamura T, Mitsuishi K, Gunawan H, Suto H, Ogawa T, Wang XL, Ikeda S, Okumura K, Ogawa H: Staphylococcus aureus extracellular protease causes epidermal barrier dysfunction. J Invest Dermatol, 130:614-617, 2010
  9. Takamura T, Harada D, Matsuoka S, Shimokawa N, Nakamura Y, Okumura K, Ogawa H, Kitamura M, Nakao A: Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice. Immunol Cell Biol, 88:685-689, 2010
  10. Shimokawa N, Nishiyama C, Nakano N, Maeda K, Suzuki R, Hara M, Fukai T, Tokura T, Miyajima H, Nakao A, Ogawa H, Okumura K: Suppressive effects of transcription factor GATA-1 on cell type-specific gene expression in dendritic cells. Immunogenetics, 62:421-429, 2010
  11. Potaczek D, Owczarek D, Cibor D, Nishiyama C, Okumura K, Mach T, Undas A: Tissue factor -1208D>I polymorphism is associated with D-dimer levels in patients with inflammatory bowel disease. Inflamm Bowel Dis, 16:1095-1096, 2010
  12. Potaczek D, Owczarek D, Okumura K, Mach T, Undas A, Nishiyama C: An association between functional FcepsilonRIalpha polymorphisms and total serum IgE levels in patients with inflammatory bowel disease. Scand J Gastroenterology, 45:766-767, 2010
  13. Takai T: Cedar allergen harvest from tobacco: Plant biotechnology for recombinant allergens. Int Arch Allergy Immunol, 153:431-433, 2010
  14. Le TA, Takai T, Vu AT, Kinoshita H, Ikeda S, Ogawa H, Okumura K: Glucocorticoids inhibit double-stranded RNA-induced thymic stromal lymphopoietin release from keratinocytes in atopic cytokine milieu more effectively than tacrolimus. Int Arch Allergy Immunol, 153:27-34, 2010
  15. Niwa Y, Potaczek D, Kanada S, Takagi A, Shimokawa N, Ito T, Mitsuishi K, Okubo Y, Tajima M, Hobo A, Ng W, Tsuboi R, Ikeda S, Ogawa H, Okumura K, Nishiyama C: FcepsilonRIalpha gene (FCER1A) promoter polymorphisms and total serum IgE levels in Japanese atopic dermatitis patients. Int J Immunogenetics 37:139-141, 2010
  16. Potaczek D, Kwasny-Krochin B, Nishiyama C, Okumura K, Gluszko P, Undas A: Tissue factor +5466A>G and -1208D>I genetic polymorphisms and severity of rheumatoid arthritis. Clin Chem Lab Med 48:423-425, 2010
  17. Ouyang Y, Miyata M, Hatsushika K, Ohnuma Y, Katoh R, Ogawa H, Okumura K, Masuyama K, Nakao A: TGF-beta signaling may play a role in the development of Goblet cell hyperplasia in a mouse model of allergic rhinitis. Allergol Int, 59:313-319, 2010
  18. Yagami A, Kajiwara N, Oboki K, Ohno N, Morita H, Sunnarborg SW, Okumura K, Ogawa H, Saito H, Nakae S: Amphiregulin is dispensable for induction of contact hypersensitivity. Allergol Int. 59:277-284, 2010
  19. Kajiwara N, Oboki K, Ohno T, Ishii A, Sunnarborg SW, Okumura K, Saito H, Nakae S: Amphiregulin is not essential for ovalbumin-induced acute airway inflammation in mice. Allergol Int, 59:207-211, 2010
  20. Oboki K, Ohno T, Kajiwara N, Saito H, Nakae S: IL-33 and IL-33 receptors in host defense and diseases. Allergol Int, 59:143-160, 2010
  21. Nambu A, Nakae S: IL-1 and allergy. Allergol Int, 59:125-135, 2010
  22. Ishii A, Oboki K, Nambu A, Morita H, Ohno T, Kajiwara N, Arae K, Sudo H, Okumura K, Saito H, Nakae S: Development of IL-17-mediated delayed-type hypersensitivity is not affected by down-regulation of IL-25 expression. Allergol Int. 59:1-20, 2010
  23. Nishida C, Nishiyama C, Satoh K, Hara M, Itoh Y, Ogawa H, Okumura K: Establishment of a simple detection system for blood group ABO-specific transferase activity in DNA-transfected cells. Legal Med, 12:172-176, 2010
  24. Vu AT, Takai T, Le TA, Kinoshita H, Kamijo S, Hara M, Wang XL, Ogawa T, Ikeda S, Ogawa H, Okumura K: Proinflammatory response in human keratinocytes stimulated with ligands for TLR2, TLR1, and TLR6. Juntendo Medical Journal, 56:50-55, 2010
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