Juntendo University, Tokyo, established in 1838.

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Department of Nephrology

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Achievements　（2012）

｜2014｜2013｜2012｜
  1. Lessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of Human Type 2 Diabetic Nephropathy. Tomino Y. Nephrourol Mon. 2012 ;4:524-9
  2. Campylobacter bacteremia in hemodialysis patients by eating raw meat - the importance of sanitary education. Shimizu Y, Ishii A, Takahata A, Kajiyama T, Yamahatsu A, Io H, Kurusu A, Hamada C, Horikoshi S, Tomino Y. Case Rep Nephrol Urol. 2012 ;2:145-51
  3. Thyroid storm masked by hemodialysis and glucocorticoid therapy in a patient with rheumatoid arthritis. Sasaki Y, Shimizu Y, Nakata J, Kameda T, Muto M, Ohsawa I, IoH, Hamada C, Horikoshi S, Tomino Y. Case Rep Nephrol Urol. 2012 ;2:6-10
  4. Predictors of prognosis in IgA nephropathy. Tomino Y. Kaohsiung J Med Sci. 2012 ;28:517-20
  5. Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR). Yokoyama H, Sugiyama H, SatoH, Taguchi T, Nagata M, Matsuo S, Makino H, Watanabe T, Saito T, Kiyohara Y, Nishi S, Iida H, Morozumi K, Fukatsu A, Sasaki T, Tsuruya K, Kohda Y, Higuchi M, Kiyomoto H, Goto S, Hattori M, Hataya H, et al. Clin Exp Nephrol. 2012 ;16:903-20
  6. Guidelines for the use and interpretation of assays for monitoring autophagy. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, et al. Autophagy. 2012 ;8:445-544
  7. Autoantibodies targeting galactose-deficient IgA1 associate with progression of IgA nephropathy. Berthoux F, Suzuki H, Thibaudin L, Yanagawa H, Maillard N, Mariat C, Tomino Y, Julian BA, Novak J. J Am Soc Nephrol. 2012 ;23:1579-87
  8. Effect of exercise on kidney function, oxidative stress, and inflammation in type 2 diabetic KK-A(y) mice. Ishikawa Y, Gohda T, Tanimoto M, Omote K, Furukawa M, Yamaguchi S, Murakoshi M, Hagiwara S, Horikoshi S, Funabiki K, Tomino Y. Exp Diabetes Res. 2012 ;2012:702948
  9. Determination of severity of murine IgA nephropathy by glomerular complement activation by aberrantly glycosylated IgA and immune complexes. Hashimoto A, Suzuki Y, Suzuki H, Ohsawa I, Brown R, Hall S, Tanaka Y, Novak J, Ohi H, Tomino Y. Am J Pathol. 2012 ;181:1338-47
  10. N-type calcium channel inhibition with cilnidipine elicits glomerular podocyte protection independent of sympathetic nerve inhibition. Lei B, Nakano D, Fujisawa Y, Liu Y, Hitomi H, Kobori H, Mori H, Masaki T, Asanuma K, Tomino Y, Nishiyama A. J Pharmacol Sci.2012 ;119:359-67
  11. Urinary podocalyxin is an early marker for podocyte injury in patients with diabetes: establishment of a highly sensitive ELISA to detect urinary podocalyxin. Hara M, Yamagata K, Tomino Y, Saito A, Hirayama Y, Ogasawara S, Kurosawa H, Sekine S, Yan K. Diabetologia. 2012 ;55:2913-9
  12. Risk of overestimation of kidney function using GFR-estimating equations in patients with low inulin clearance. Nakata J, Ohsawa I, Onda K, Tanimoto M, Kusaba G, Takeda Y, Kobayashi N, Asanuma K, Tanaka Y, Sato M, Inami Y, Suzuki H, Suzuki H, Masuda A, Nonaka K, Sasaki Y, Hisada A, Hamada C, Horikoshi S, Tomino Y. J Clin Lab Anal. 2012 ;26:248-53
  13. Development of a model of early-onset IgA nephropathy. Okazaki K, Suzuki Y, Otsuji M, Suzuki H, Kihara M, Kajiyama T, Hashimoto A, Nishimura H, Brown R, Hall S, Novak J, Izui S, Hirose S, Tomino Y. J Am Soc Nephrol. 2012 ;23:1364-74
  14. Successfully maintained hemodialysis for the treatment of chronic renal failure in a patient with Hallopeau-Siemens type recessive dystrophic epidermolysis bullosa. Iida H, Hasegawa T, Okuma K, Io H, Tomino Y, Ikeda S. J Dermatol. 2012;39:1088-9
  15. Relationships between levels of urinary podocalyxin, number of urinary podocytes, and histologic injury in adult patients with IgA nephropathy. Asao R, Asanuma K, Kodama F, Akiba-Takagi M, Nagai-Hosoe Y, Seki T, Takeda Y, Ohsawa I, Mano S, Matsuoka K, Kurosawa H, Ogasawara S, Hirayama Y, Sekine S, Horikoshi S, Hara M, Tomino Y. Clin J Am Soc Nephrol. 2012 ;7:1385-93
  16. Rivaroxaban vs. Warfarin in Japanese Patients With Atrial Fibrillation - The J-ROCKET AF Study - . Hori M, Matsumoto M, Tanahashi N, Momomura S, Uchiyama S, Goto S, Izumi T, Koretsune Y,　Kajikawa M, Kato M, Ueda H, Iwamoto K, Tajiri M; J-ROCKET AF study investigators. Circ J. 2012 ;76:2104-11
  17. Differentiation of bone marrow-derived cells into regenerated mesothelial cells in peritoneal remodeling using a peritoneal fibrosis mouse model. Sekiguchi Y, Hamada C, Ro Y, Nakamoto H, Inaba M, Shimaoka T, Io H, Koyanagi I, Aruga S, Inuma J, Kaneko K, Hotta Y, Margetts PJ, Mochizuki H, Horikoshi S, Tomino Y. J Artif Organs. 2012 ;15:272-82
  18. Pathological scenario with the mannose-binding lectin in patients with IgA nephropathy. Ohsawa I, Ishii M, Ohi H, Tomino Y. J Biomed Biotechnol. 2012 ;2012:476739
  19. Experimental models of type-2 diabetic nephropathy. Tomino Y, Cooper ME, Kurtz TW, Shimizu Y. Exp Diabetes Res. 2012 ;2012:218917
  20. A new screening method for proteinuria using Erythrosin B and an automated analyzer--rapid, sensitive and inexpensive determination. Horikoshi S, Higurashi A, Kaneko E, Yoshimura H, Ohsawa I, Suzuki Y, Hamada C, Tomino Y. Clin Chim Acta. 2012 ;413:1087-91
  21. Significance of broad distribution of electron-dense deposits in patients with IgA nephropathy. Kusaba G, Ohsawa I, Ishii M, Inoshita H, Takagi M, Tanifuji C, Takahashi K, Nakamoto J, Yoshida M, Ohi H, Horikoshi S, Kurihara H, Tomino Y. Med Mol Morphol. 2012 ;45:29-34
  22. Asymmetric dimethylarginine: a novel cardiovascular risk factor in end-stage renal disease. Alsagaff MY, Thaha M, Aminuddin M, Yogiarto RM, Yogiantoro M, Tomino Y. J Int Med Res. 2012 ;40:340-9
  23. Significance of urinary full-length and ectodomain forms of megalin in patients with type 2 diabetes. Ogasawara S, Hosojima M, Kaseda R, Kabasawa H, Yamamoto-Kabasawa K, Kurosawa H, Sato H, Iino N, Takeda T, Suzuki Y, Narita I, Yamagata K, Tomino Y, Gejyo F, Hirayama Y, Sekine S, Saito A. Diabetes Care. 2012 ;35:1112-8
  24. Risk factors associated with increased left ventricular mass index in chronic kidney disease patients evaluated using echocardiography. Matsumoto M, Io H, Furukawa M, Okumura K, Masuda A, Seto T, Takagi M, Sato M, Nagahama L, Omote K, Hisada A, Horikoshi S, Tomino Y. J Nephrol. 2012 ;25:794-801
  25. Effects of acetate-free citrate dialysate on glycoxidation and lipid peroxidation products in hemodialysis patients. Masuda A, Hagiwara S, Tanimoto M, Kodama F, Okumura K, Nohara N, Matsumoto M, Maiguma M, Omote K, Io H, Kurusu A, Ohsawa I, Shimizu Y, Hamada C, Horikoshi S, Tomino Y. Nephron Extra. 2012 ;2:256-68
  26. Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis. Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y. Am J Nephrol. 2012 ;35:58-68
  27. Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response. Sekiguchi Y, Zhang J, Patterson S, Liu L, Hamada C, Tomino Y, Margetts PJ. J Cell Mol Med. 2012 ;16:1934-45
  28. Relationship between preoperative radial artery and postoperative arteriovenous fistula blood flow in hemodialysis patients. Sato M, Io H, Tanimoto M, Shimizu Y, Fukui M, Hamada C, Horikoshi S, Tomino Y. J Nephrol. 2012 ;25:726-31
  29. Doxorubicin-induced glomerulosclerosis with proteinuria in GFP-GABARAP transgenic mice. Takagi-Akiba M, Asanuma K, Tanida I, Tada N, Oliva Trejo JA, Nonaka K, Asanuma E, Kominami E, Ueno T, Tomino Y. Am J Physiol Renal Physiol. 2012 ;302:F380-9
  30. Mechanisms and interventions in peritoneal fibrosis. Tomino Y. Clin Exp Nephrol. 2012 ;16:109-14
  31. Severity-based treatment for Japanese patients with MPO-ANCA-associated vasculitis: the JMAAV study. Ozaki S, Atsumi T, Hayashi T, Ishizu A, Kobayashi S, Kumagai S, Kurihara Y, Kurokawa MS, Makino H, Nagafuchi H, Nakabayashi K, Nishimoto N, Suka M, Tomino Y, Yamada H, Yamagata K, Yoshida M, Yumura W, Amano K, Arimura Y, Hatta K, Ito S, et al. Mod Rheumatol. 2012 ;22:394-404
  32. Tonsillar TLR9 expression and efficacy of tonsillectomy with steroid pulse therapy in IgA nephropathy patients. Sato D, Suzuki Y, Kano T, Suzuki H, Matsuoka J, Yokoi H, Horikoshi S, Ikeda K, Tomino Y. Nephrol Dial Transplant. 2012 ;27:1090-7
  33. Identification of quantitative trait loci for diabetic nephropathy in KK-Ay/Ta mice. Aoki T, Kaneko S, Tanimoto M, Gohda T, Hagiwara S, Murakoshi M, Ishikawa Y, Furukawa M, Funabiki K, Horikoshi S, Tomino Y. J Nephrol. 2012 ;25:127-36
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