Juntendo University, Tokyo, established in 1838.

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Department of Neurosurgery

Research

1.Brain tumors

 At present, graduate school students perform research on brain tumors in this graduate university campus and institutions overseas such as Chicago University and the hospital of sick children in Toronto Canada. They perform molecular biological and immunological analyses of genetic abnormalities in brain tumors (particularly brain tumors/medulloblastoma in children) and evaluate their association with clinical characteristics and treatment results.

2.Cerebrovascular disease

 Our department performs joint studies with the Department of Medical Engineering of the National Defense Medical College, which has made advances in medical engineering. The major contents of research are as follows.
  1. Production of animal models for studies on carotid artery stenosis, clarification of pathophysiology using animal models, and studies/development of devices
  2. Development of biomaterials for endovascular treatment for cerebral aneurysms
  3. Development of embolization materials applicable for brain tumors and vascular anomalies
 

Experimental aneurysm (produced by side-to-side anastomosis between the rabbit carotid artery and jugular vein)

3.Cerebral circulation/metabolism

 Graduate students perform research on cerebral blood flow and metabolism, at the National Institute of Health (NIH), the U.S.

4.Nerve regeneration, grafting

 Regeneration studies are performed using rat amniotic cells. The future goal is their clinical application.

5.Hydrocephalus

 Our department clinically specializes in pediatric neurosurgery and hydrocephalus, in addition to conducting their basic studies. Associate Prof. Miyajima is leading these studies.

6.Spina bifida

 Spina bifida is also a major disorder in the department of pediatric neurosurgery. Studies on its developmental mechanism were also initiated.

7.Neurogenesis

 The hippocampus is an area associated with neurogenesis. Studies are performed to confirm neurogenesis in the hippocampus and clarify the meaning of neurogenesis, aiming at applying obtained results to nerve grafting and clarifying the pathology of various types of epilepsy.
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