YOKOMIZO Takehiko, M.D., Ph.D.

Department of Molecular and Cellular Biochemistry

Short Biography

M.D. The University of Tokyo Faculty of Medicine
Ph.D. The University of Tokyo Graduate School of Medicine
Postdoctoral Fellow (JSPS Fellow), The University of Tokyo
Research Associate, The University of Tokyo
Associate Professor, The University of Tokyo
Professor, Kyushu University
Professor, Department of Molecular and Cellular Biochemistry, Juntendo University Faculty of Medicine
Program Officer, AMED

Main Research Topics and Interests

  • Lipid mediators (Leukotriene, Prostaglandin)
  • Omega-3 fatty acids
  • G-protein coupled receptor
  • Knockout mice
  • Mass spectrometry

Publications (in English)

  • Original Articles: 133
  • Review Articles: 28
  • Books: 28
  • h-Index: 51 (Google Scholar)
  • Sum of Times Cited: 13,568 (Google Scholar)

Recent Main Publications

  • Koga T., Sasaki F., Saeki K., Tsuchiya S., Okuno T., Ohba M., Ichiki T., Iwamoto S., Uzawa H., Kitajima K., Meno C., Nakamura E., Tada N., Fukui Y., Kikuta J., Ishii M., Sugimoto Y., Nakao M., Yokomizo T. Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation. Cell Mol Immunol 18, 1437-1449 (2021)
  • Hara T., Saeki K., Jinnouchi H., Kazuno S., Miura Y., Yokomizo T. The c-terminal region of BLT2 restricts its localization to the lateral membrane in a LIN7C-dependent manner. FASEB J 35, e21364 (2021)
  • Yokomizo T., Nakamura M., Shimizu T. Leukotriene receptors as potential therapeutic targets. J Clin Invest 128, 2691-2701 (2018)
  • More

Other Specific Comments

  • Prof. Yokomizo is famous for his cloning of leukotriene B4 receptors (Nature 1997 and JEM 2000). He is a leader of lipid research in Japan, and mainly working on GPCRs on lipid mediators using biochemistry, immunology and gene targeting. English-speaking ability is required.