Institute for Environmental and Gender-Specific Medicine
Kenji Takamori, M.D., Ph.D.
(Trustee, Juntendo University)
(Specially Appointed Professor, Department of Dermatology and Allergology)
Iwao Sekigawa, M.D., Ph.D.
(Professor, Department of Internal Medicine and Rheumatology)
Hitoshi Nakayama, Ph.D.
(Assistant Professor, Faculty of Health Care and Nursing)
Adjunct Assistant Professor (Lecturer) ：
Hiroshi Yoshitake, M.D., Ph.D.
Adjunct Assistant Professors：
Yayoi Kamata, Ph.D.
(JSPS Research Fellow)
Atsuko Kamo, Ph.D.
(The School of Health Sciences, Tokai University)
Yoshie Umehara, Ph.D.
Kunihiro Hayakawa, Ph.D.
Ekyalongo Roudy, M.D., Ph.D.
Eriko Suyama, Ph.D.
Hyeon-Cheol Lee, Ph.D.
Hiroaki Kawasaki, Ph.D. (Project researcher)
Masaru Kurosawa, Ph.D.
Shozo Ichinose (non-regular)
Assistant Technical Staff：
Maki Fujishiro, M.S.
Masako Miura, M.S.
Noriko Yokoyama, Ph.D.
Yuko Yoshida, Ph.D.
Kyi Chan Ko, Ph.D. (non-regular)
Kensuke Hamamura, M.D.
Takuya Hirai, M.D.
Hiroshi Tsushima, M.D.
Yasuyuki Igarashi, Ph.D.
(Dept. of Biomembrane and Biofunctional Chemistry, Grad. Sch. of Pharmaceutical Sciences, Hokkaido Univ.)
Kenji Izuhara, M.D., Ph.D.
(Div. of Medical Biochemistry, Dept. of Biomolecular Sciences, Saga Medical School)
Ryusuke Kakigi, M.D., Ph.D.
(Department of Sensory-Motor Integration, National Institute for Physiological Sciences)
Kiyoshi Kita, Ph.D.
(Dept. of Biomedical Chemistry, Grad. Sch. of Medicine, Univ. of Tokyo)
Kunio Shiota, D.V.M., Ph.D.
(Laboratory of Cellular Biochemistry, Grad. School of Agricultural and Life. Univ. of Tokyo)
Yoshio Hirabayashi, Ph.D.
(RIKEN Brain Science Institute)
Hiroshi Matsuda, D.V.M., Ph.D.
(Div. of Animal Life Science, Inst. of Agriculture, Tokyo Univ. of Agriculture and Technology)
Ikuro Maruyama, M.D., Ph.D.
(Dept. of System Biology in Thromboregulation, Kagoshima Univ. Grad. Sch. of Medical and Dental Sciences)
Shigeki Yamaguchi, M.D., Ph.D.
(Dept. of Anesthesiology, Dokkyo Medical University)
Naoki Yamamoto, M.D., Ph.D.
(Dept. of Microbiology, National Univ. of Singapore)
Sakurai Takashi, M.D., Ph.D.
(Prof. Dept. of Cellular and Molecular Pharmacology)
Takao Urabe, M.D., Ph.D.
(Prof. Dept. of Neurology)
Tsuneo Kitamura, M.D., Ph.D.
(Assoc.Prof. Dept. of Gastroenterology)
Masato Koike, M.D., Ph.D.
(Prof. Dept. of Cell Biology and Neuroscience)
Yasushi Suga, M.D., Ph.D.
(Prof. Dept. of Dermatology and Allergology)
Kuniaki Seyama, M.D., Ph.D.
(Assoc.Prof. Dept. of Respiratory Medicine)
Hiroshi Tanaka, M.D., Ph.D.
(Prof. Dept. of Emergency and critical care medicine)
Hisashi Naito, Ph.D.
(Prof. Grad Sch. of Health and Sports Science)
Sachiko Miyake, M.D., Ph.D.
(Prof. Dept. of Immunology)
Chikao Morimoto, M.D.,
(Visiting Prof. Dept. of Therapy Development and Innovation for Immune disorders and Cancers)
Fumiyuki Yamakura, Ph.D.
(Prof. Grad Sch. of Health Care and Nursing)
Takehiko Yokomizo, M.D., Ph.D.
(Prof. Dept. of Molecular and Cellular Biochemistry)
Hirotaka Watada, M.D., Ph.D
(Prof. Dept. of Medicine, Metabolism and Endocrinology)
PrefaceThe Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine (Original Director: Hideoki Ogawa, M.D., Ph.D.), was founded in April 2002, supported in part by the "High-Tech Research Center" Project for Private Universities: matching fund subsidy from the Ministry of Education, Culture, Sports, Science and Technology, Japan.
At present, three research categories are working on the field of environmental/gender-specific medicine or related fields. In addition to the faculty members, several researchers in Juntendo or other universities have been appointed as visiting faculty members, and they are pursuing several collaborative studies. The main research fields focused on in our institute are the following:
- Biological effects of environmental factors (environmental pollutants)
- The relationship between environmental factors and their effects on disease-related genes
- Gender specific medicine
For graduate students, we have a course concerning “Environmental and Gender-Specific Medicine,” organized by faculty members. Here are the topics of our research including collaborators.
① Molecular mechanisms of epidermal innervation
② The effect of environmental factors on atopic dermatitis
③ Evaluation of the effect of exogenous endocrine disrupting chemicals on the innate immune system
④ Molecular dynamics of escape mechanisms of mycobacterium from neutrophil killing.
⑤ Study of structure and signal transduction mechanisms of glycosphingolipid-supramolecular
domains involved in adhesion, migration and phagocytosis of leukocytes
⑥ Development and applications of immunoassay for the quantification of oxidative stress marker,
⑦ Biological effects of metals during environmental changesn
⑧ Pathological effect of cigarette smoke chronic exposure on the progression of pulmonarys
emphysema and regenerative effect of retinoid on the pulmonary alveolus.
⑨ Mechanisms of autoimmunity induced by drug administration
⑩ Development of new strategies for autoimmune disease therapy
⑪ Pathogenetical mechanisms of systemic lupus erythematodes (SLE)
⑫ Disorder of gene transcription and autoimmunity: epigenetic analysis
⑬ Effects of the sex hormones on DNA transcription
⑭ Proteomic analysis of the patients with rheumatoid arthritis and other autoimmune diseases
⑮ Pathogenesis of lymphangioleiomyomatosis
⑯ Biological significance of sexual dimorphism on the gametogenesis.
⑰ Biological function(s) of glycosylphosphatidylinositol-anchored proteins in mammals.otein in mammals.