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2012-2010年 研究業績

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1) Noto D, Takahashi K, Miyake S, Yamada M: In vitro differentiation of lineage-negative bone marrow cells into microglia-like cells. Eur J Neurosci 31:1155-63, 2010

2) Sakuishi K, Miyake S, Yamamura T: Role of NKT cells in multiple sclerosis: In a quest to understand and overcome their highly efficient double edged swords. Molecular Basis of Multiple Scoerosis. The Immune System Series "Results and Problems in Cell Differentiation" Gramm U, ed, Springer-Verlag, Heidelberg, 51:127-147, 2010

3) Chihara N, Aranami T, Sato W, Miyazaki Y, Miyake S, Okamoto T, Ogawa M, Toda T, Yamamura T: Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. Proc Natl Acad Sci USA 108(9):3701-3706, 2011

4) Miyazaki Y, Miyake S, Chiba A, Lantz O, Yamamura T. Mucosal-associated invariant T cells regulate Th1 response Int Immunol. 2011 Sep;23(9):529-35 in multiple sclerosis. Int Immunol 23(9):529-535, 2011

5) Chiba A, Tajima R, Tomi C, Miyazaki Y, Yamamura T, Miyake S: Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis Arthritis Rheum. 2012 Jan;64(1):153-61

6) Ichikawa D, Mizuno M, Yamamura T, Miyake S.: Gene related to anergy in lymphocytes (GRAIL) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3-5 and coronin 1A. J Biol Chem. 286(50):43465-74, 2011

7) Miyake S.: Mind over cytokines: Crosstalk and regulation between the neuroendocrine and immune systems, Clinical and Experimental Neuroimmunology, Article first published online: 8 JUL 2011

8) Chiba A, Mizuno M, Tomi C, Tajima R, Alloza I, di Penta A, Yamamura T, Vandenbroeck K, Miyake S: A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation.Arthritis Res Ther. 2012 Jan 17;14(1):R9

9) Toba T, Murata K, Futamura J, Nakanishi K, Takahashi B, Takemoto N, Tomino M, Nakatsuka T, Seiichi Imajo S, Goto M, Yamamura T, Miyake S, Annoura H: Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile. Bioorg & Medic Chem 20:2850-2859, 2012

10) Yamamura T, Miyake S: Editorial. B-cell-directed therapy. Which B cells should be targeted and how? Immunother 4:1-3, 2012

11) Araki M, Aranami T, Matsuoka T, Nakamura M, Miyake S, Yamamura T.: Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab. Modern Rheumatol published online, (11 July 2012)

12) Yamamura T, Miyake S. : B-cell-directed therapy: which B cells should be targeted and how? Immunotherapy 4: 455-457, 2012

13) Chiba A, Tajima R, Tomi C, Miyazaki Y, Yamamura T, Miyake S. : Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis. Arthritis Rheum 64: 153-161, 2012

14) Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, Ogawa M, Okamoto T, Murata M, Kuroiwa Y, Aranami T, Yamamura T CCR2+CCR5+ T cells produce matrix metalloproteinase-p and osteopontin in the pathogenesis of multiple sclerosis. J Immunol 189: 5057-5065, 2012


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