Juntendo
  Japanese
top topics access messages department profile Health and Sports Science
Department of Ophthalmology
Top | Introduction | Staff | Research | Education | Achievements | Apply | Links | Japanese | Index
achievements
References (2002-2004)
 2004
  1. Aramaki, O., et al., Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen. Transplantation, 2004. 77(1): p. 6-12.
  2. Cho, H.R., et al., Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival. Transpl Int, 2004. 17(7): p. 351-61.
  3. Hase, H., et al., BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood, 2004. 103(6): p. 2257-65.
  4. Inazaki, K., et al., Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction. Kidney Int, 2004. 66(2): p. 597-604.
  5. Jin, L., et al., Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes. J Invest Dermatol, 2004. 122(5): p. 1175-9.
  6. Kasuga, C., et al., Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors. Cancer Sci, 2004. 95(10): p. 840-4.
  7. Kohyama, M., et al., Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen. Proc Natl Acad Sci U S A, 2004. 101(12): p. 4192-7.
  8. Kudo, T., et al., Polarized Production of T-Helper Cell Type 1 Cells in Peyer's Patches in Crohn's Disease. Digestion, 2004. 70(4): p. 214-225.
  9. Nishiyama, C., et al., Polymorphisms in the Fc epsilon RI beta promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between Fc epsilon RI beta and atopy. J Immunol, 2004. 173(10): p. 6458-64.
  10. Nishiyama, C., et al., Evidence against requirement of Ser41 and Ser45 for function of PU.1 -- molecular cloning of rat PU.1. FEBS Lett, 2004. 572(1-3): p. 57-64.
  11. Nishiyama, C., et al., Functional analysis of PU.1 domains in monocyte-specific gene regulation. FEBS Lett, 2004. 561(1-3): p. 63-8.
  12. Nishiyama, C., et al., Overproduction of PU.1 in mast cell progenitors: its effect on monocyte- and mast cell-specific gene expression. Biochem Biophys Res Commun, 2004. 313(3): p. 516-21.
  13. Sasazuki, T., et al., Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS. Mol Immunol, 2004. 41(5): p. 547-51.
  14. Seko, Y., et al., Expression of costimulatory molecules (4-1BBL and Fas) and major histocompatibility class I chain-related A (MICA) in aortic tissue with Takayasu's arteritis. J Vasc Res, 2004. 41(1): p. 84-90.
  15. Sumiyoshi, K., et al., Exogenous Smad3 accelerates wound healing in a rabbit dermal ulcer model. J Invest Dermatol, 2004. 123(1): p. 229-36.
  16. Suzui, M., et al., Natural killer cell lytic activity and CD56(dim) and CD56(bright) cell distributions during and after intensive training. J Appl Physiol, 2004. 96(6): p. 2167-73.
  17. Takeda, K., et al., TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood, 2004.
  18. Takeda, K. and K. Okumura, CAM and NK Cells. Evid Based Complement Alternat Med, 2004. 1(1): p. 17-27.
  19. Takeda, K., et al., Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy. J Exp Med, 2004. 199(4): p. 437-48.
  20. Tani, K., et al., Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. Mol Ther, 2004. 10(4): p. 799-816.
  21. Ushio, H., et al., MD-2 is required for the full responsiveness of mast cells to LPS but not to PGN. Biochem Biophys Res Commun, 2004. 323(2): p. 491-8.
  22. Xu, H., et al., TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF. Biochem Biophys Res Commun, 2004. 318(2): p. 422-7.
  23. Yagita, H., et al., TRAIL and its receptors as targets for cancer therapy. Cancer Sci, 2004. 95(10): p. 777-83.
 2003
  1. Akizawa, Y., et al., Regulation of human FcepsilonRI beta chain gene expression by Oct-1. Int Immunol, 2003. 15(5): p. 549-56.
  2. Aramaki, O., et al., CD27/CD70, CD134/CD134 ligand, and CD30/CD153 pathways are independently essential for generation of regulatory cells after intratracheal delivery of alloantigen. Transplantation, 2003. 76(5): p. 772-6.
  3. Dan, N., et al., Ameliorating effect of anti-Fas ligand MAb on wasting disease in murine model of chronic colitis. Am J Physiol Gastrointest Liver Physiol, 2003. 285(4): p. G754-60.
  4. Funaki, T., et al., Smad7 suppresses the inhibitory effect of TGF-beta2 on corneal endothelial cell proliferation and accelerates corneal endothelial wound closure in vitro. Cornea, 2003. 22(2): p. 153-9.
  5. Hasegawa, M., et al., A novel -66T/C polymorphism in Fc epsilon RI alpha-chain promoter affecting the transcription activity: possible relationship to allergic diseases. J Immunol, 2003. 171(4): p. 1927-33.
  6. Hasegawa, M., et al., Regulation of the human Fc epsilon RI alpha-chain distal promoter. J Immunol, 2003. 170(7): p. 3732-8.
  7. Hirano, T., et al., [The chimerism and GVT effects on murine mini-transplantation model]. Nippon Rinsho, 2003. 61(9): p. 1527-34.
  8. Hoshino, A., et al., Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma. Eur J Immunol, 2003. 33(4): p. 861-9.
  9. Iwai, H., et al., Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis. J Immunol, 2003. 171(6): p. 2848-54.
  10. Kanai, T., et al., Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J Immunol, 2003. 171(8): p. 4156-63.
  11. Kanamaru, Y., et al., Involvement of p300 in TGF-beta/Smad-pathway-mediated alpha2(I) collagen expression in mouse mesangial cells. Nephron Exp Nephrol, 2003. 95(1): p. e36-42.
  12. Kirii, Y., et al., Molecular cloning, functional characterization, and enzyme-linked immunosorbent assay of cynomolgus monkey Fas ligand. J Immunol Methods, 2003. 278(1-2): p. 201-9.
  13. Maeda, K., et al., Regulation of cell type-specific mouse Fc epsilon RI beta-chain gene expression by GATA-1 via four GATA motifs in the promoter. J Immunol, 2003. 170(1): p. 334-40.
  14. Miura, Y., et al., Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection. Proc Natl Acad Sci U S A, 2003. 100(5): p. 2777-82.
  15. Miyahira, Y., et al., Cutting edge: a potent adjuvant effect of ligand to receptor activator of NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination. J Immunol, 2003. 171(12): p. 6344-8.
  16. Miyahira, Y., et al., Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections. Immunol Lett, 2003. 89(2-3): p. 193-9.
  17. Miyahira, Y., et al., Critical contribution of CD28-CD80/CD86 costimulatory pathway to protection from Trypanosoma cruzi infection. Infect Immun, 2003. 71(6): p. 3131-7.
  18. Miyahira, Y., et al., Activation of natural killer T cells by alpha-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi. Infect Immun, 2003. 71(3): p. 1234-41.
  19. Muto, T., et al., Prevalence of atopic dermatitis in Japanese adults. Br J Dermatol, 2003. 148(1): p. 117-21.
  20. Nakayama, M., et al., Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem Biophys Res Commun, 2003. 306(4): p. 819-25.
  21. Nakayama, M., et al., Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. J Immunol, 2003. 170(1): p. 341-8.
  22. Nishiyama, C., et al., Molecular cloning of rat transcription factor YY1. Biosci Biotechnol Biochem, 2003. 67(3): p. 654-8.
  23. Okazaki, T., et al., Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses. Biochem Biophys Res Commun, 2003. 300(4): p. 807-12.
  24. Sakon, S., et al., NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. Embo J, 2003. 22(15): p. 3898-909.
  25. Shirasugi, N., et al., Role of the CTLA4 pathway in hyporesponsiveness induced by intratracheal delivery of alloantigen. Transplantation, 2003. 75(10): p. 1636-9.
  26. Sumiyoshi, K., et al., Smads regulate collagen gel contraction by human dermal fibroblasts. Br J Dermatol, 2003. 149(3): p. 464-70.
  27. Sumiyoshi, K., et al., TGF-beta/Smad signaling inhibits IFN-gamma and TNF-alpha-induced TARC (CCL17) production in HaCaT cells. J Dermatol Sci, 2003. 31(1): p. 53-8.
  28. Suzuki, Y., et al., Pre-existing glomerular immune complexes induce polymorphonuclear cell recruitment through an Fc receptor-dependent respiratory burst: potential role in the perpetuation of immune nephritis. J Immunol, 2003. 170(6): p. 3243-53.
  29. Tajima, A., et al., Blastocyst MHC, a putative murine homologue of HLA-G, protects TAP-deficient tumor cells from natural killer cell-mediated rejection in vivo. J Immunol, 2003. 171(4): p. 1715-21.
  30. Totsuka, T., et al., Therapeutic effect of anti-OX40L and anti-TNF-alpha MAbs in a murine model of chronic colitis. Am J Physiol Gastrointest Liver Physiol, 2003. 284(4): p. G595-603.
  31. Totsuka, T., et al., Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis. Gastroenterology, 2003. 124(2): p. 410-21.
  32. Tsuge, T., et al., Monocyte chemoattractant protein (MCP)-1 production via functionally reconstituted Fcalpha receptor (CD89) on glomerular mesangial cells. Inflamm Res, 2003. 52(10): p. 428-32.
  33. Tsuji, H., et al., Concurrent induction of T-cell activation and apoptosis of osteosarcoma cells by adenovirus-mediated B7-1/Fas chimeric gene transfer. Cancer Gene Ther, 2003. 10(9): p. 717-25.
  34. Tsushima, F., et al., Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses. Eur J Immunol, 2003. 33(10): p. 2773-82.
  35. Uno, K., et al., TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells. Blood, 2003. 101(9): p. 3658-67.
  36. Warnnissorn, P., et al., Tumour necrosis factor-related apoptosis-inducing ligand expression in atopic dermatitis. Br J Dermatol, 2003. 148(4): p. 829-31.
  37. Wongpiyabovorn, J., et al., Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis. J Dermatol Sci, 2003. 33(1): p. 31-40.
  38. Yokoi, H., et al., The role and expression of CD27 and CD70 lymphocytes in the human tonsil. Lymphology, 2003. 36(2): p. 74-83.
 2002
  1. 62. Akiyama, Y., et al., B7/CTLA4 pathway is essential for generating regulatory cells after intratracheal delivery of alloantigen in mice. Transplantation, 2002. 74(5): p. 732-8.
  2. 63. Ebihara, N., et al., High level of Fc epsilon receptor I-bindable immunoglobulin E in the tear fluid and increased immunoglobulin E-saturated cells in the giant papillae of vernal keratoconjunctivitis patients. Jpn J Ophthalmol, 2002. 46(4): p. 357-63.
  3. 64. Futagawa, T., et al., Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int Immunol, 2002. 14(3): p. 275-86.
  4. 65. Harada, N., et al., Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells. Biochem Biophys Res Commun, 2002. 299(3): p. 488-93.
  5. 66. Hase, H., et al., CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. J Biol Chem, 2002. 277(49): p. 46950-8.
  6. 67. Hayakawa, Y., et al., IFN-gamma-mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, alpha-galactosylceramide. Blood, 2002. 100(5): p. 1728-33.
  7. 68. Iwai, H., et al., Amelioration of collagen-induced arthritis by blockade of inducible costimulator-B7 homologous protein costimulation. J Immunol, 2002. 169(8): p. 4332-9.
  8. 69. Kagaya, F., et al., Inhibition of murine corneal allograft rejection by treatment with antibodies to CD80 and CD86. Exp Eye Res, 2002. 74(1): p. 131-9.
  9. 70. Kanamaru, Y., et al., Chronic graft-versus-host autoimmune disease in Fc receptor gamma chain-deficient mice results in lipoprotein glomerulopathy. J Am Soc Nephrol, 2002. 13(6): p. 1527-33.
  10. 71. Katae, M., et al., Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy. Infect Immun, 2002. 70(9): p. 4833-40.
  11. 72. Kayagaki, N., et al., Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL). Cell Immunol, 2002. 219(2): p. 82-91.
  12. 73. Kobayashi, N., et al., FcRn-mediated transcytosis of immunoglobulin G in human renal proximal tubular epithelial cells. Am J Physiol Renal Physiol, 2002. 282(2): p. F358-65.
  13. 74. Kojima, Y., et al., Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity. Biochem Biophys Res Commun, 2002. 296(2): p. 328-36.
  14. 75. Li, Q., et al., Organophosphorus pesticides markedly inhibit the activities of natural killer, cytotoxic T lymphocyte and lymphokine-activated killer: a proposed inhibiting mechanism via granzyme inhibition. Toxicology, 2002. 172(3): p. 181-90.
  15. 76. Matsumura, R., et al., Expression of TNF-related apoptosis inducing ligand (TRAIL) on infiltrating cells and of TRAIL receptors on salivary glands in patients with Sjogren's syndrome. Clin Exp Rheumatol, 2002. 20(6): p. 791-8.
  16. 77. Miyajima, H., et al., Rat monoclonal anti-murine IgE antibody removes IgE molecules already bound to mast cells or basophilic leukemia cells, resulting in the inhibition of systemic anaphylaxis and passive cutaneous anaphylaxis. Int Arch Allergy Immunol, 2002. 128(1): p. 24-32.
  17. 78. Nakao, A., et al., Expression of Smad7 in bronchial epithelial cells is inversely correlated to basement membrane thickness and airway hyperresponsiveness in patients with asthma. J Allergy Clin Immunol, 2002. 110(6): p. 873-8.
  18. 79. Nakao, A., K. Okumura, and H. Ogawa, Smad7: a new key player in TGF-beta-associated disease. Trends Mol Med, 2002. 8(8): p. 361-3.
  19. 80. Nakayama, M., et al., Multiple pathways of TWEAK-induced cell death. J Immunol, 2002. 168(2): p. 734-43.
  20. 81. Nishiyama, C., et al., Analysis of transactivation region of Elf-1 by using a yeast one-hybrid system. Biosci Biotechnol Biochem, 2002. 66(5): p. 1105-7.
  21. 82. Nishiyama, C., et al., Regulation of human Fc epsilon RI alpha-chain gene expression by multiple transcription factors. J Immunol, 2002. 168(9): p. 4546-52.
  22. 83. Sagara, H., et al., Activation of TGF-beta/Smad2 signaling is associated with airway remodeling in asthma. J Allergy Clin Immunol, 2002. 110(2): p. 249-54.
  23. 84. Sasazuki, T., et al., Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death. J Biol Chem, 2002. 277(32): p. 28853-60.
  24. 85. Seko, Y., et al., Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy. Cardiovasc Pathol, 2002. 11(3): p. 166-70.
  25. 86. Seko, Y., et al., Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3. J Am Coll Cardiol, 2002. 39(8): p. 1399-403.
  26. 87. Sumiyoshi, K., et al., Transforming growth factor-beta1 suppresses atopic dermatitis-like skin lesions in NC/Nga mice. Clin Exp Allergy, 2002. 32(2): p. 309-14.
  27. 88. Supajatura, V., et al., Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity. J Clin Invest, 2002. 109(10): p. 1351-9.
  28. 89. Supajatura, V., et al., Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines. J Immunol, 2002. 168(6): p. 2603-7.
  29. 90. Suzuki, Y., et al., Susceptibility to T cell-mediated injury in immune complex disease is linked to local activation of renin-angiotensin system: the role of NF-AT pathway. J Immunol, 2002. 169(8): p. 4136-46.
  30. 91. Suzuki, R., et al., Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta. Int Immunol, 2002. 14(4): p. 339-45.
  31. 92. Takai, T., et al., Maturation of the activities of recombinant mite allergens Der p 1 and Der f 1, and its implication in the blockade of proteolytic activity. FEBS Lett, 2002. 531(2): p. 265-72.
  32. 93. Takeda, K., et al., Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J Exp Med, 2002. 195(2): p. 161-9.
  33. 94. Uchida, T., et al., Preferential expression of T(h)2-type chemokine and its receptor in atopic dermatitis. Int Immunol, 2002. 14(12): p. 1431-8.
  34. 95. Uchida, T., et al., Quinapril treatment restores the vasodilator action of insulin in fructose-hypertensive rats. Clin Exp Pharmacol Physiol, 2002. 29(5-6): p. 381-5.
  35. 96. Yamada, M., et al., Selective accumulation of CCR4+ T lymphocytes into renal tissue of patients with lupus nephritis. Arthritis Rheum, 2002. 46(3): p. 735-40.
  36. 97. Yamazaki, T., et al., Expression of programmed death 1 ligands by murine T cells and APC. J Immunol, 2002. 169(10): p. 5538-45.
Top | Introduction | Staff | Research | Education | Achievements | Apply | Links | Japanese | Index
Copyright © 2005 JUNTENDO All Rights Reserved.
president dean School of Medicine Graduate School of Medicine