感染制御科学研究センター
※2019年度（2020.3.31）終了
研究業績データ
研究業績（2020年）NEW
主な研究業績（2019年）NEW
| 1 | Uehara Y, Sasaki T, Baba T, Lu Y, Imajo E, Sato Y, Tanno S, Furuichi M, Kawada M, Hiramatsu K. Regional outbreak of community-associated methicillin-resistant Staphylococcus aureus ST834 in Japanese children. BMC Infect Dis. 2019 Jan 9;19(1):35. |
| 2 | Tan XE, Neoh HM, Cui L, Hiramatsu K, Jamal R.Oxidative stress resistance and fitness-compensatory response in vancomycin-intermediate Staphylococcus aureus (VISA). Can J Microbiol. 2019 Aug;65(8):623-628. |
| 3 | Takahashi M, Ishikawa D, Sasaki T, Lu YJ, Kuwahara-Arai K, Kamei M, Shibuya T, Osada T, Hiramatsu K, Nagahara A. Faecal freezing preservation period influences colonization ability for faecal microbiota transplantation. J Appl Microbiol. 2019 Mar;126(3):973-984. |
| 4 | Kuwahara-Arai K, Morito A, Yanagisawa I, Hishinuma T, Mya S, Zan KN, Tohya M, Tada T, Tin HH, Sekiguchi JI, Watanabe S, Kirikae T. Evaluation of a new selective agar medium for detection of carbapenem-resistant Enterobacteriaceae. Diagn Microbiol Infect Dis., 2019 Aug 7:114882. |
| 5 | Tohya M, Watanabe S, Teramoto K, Shimojima M, Tada T, Kuwahara-Arai K, War MW, San Mya MW, Tin HH, Kirikae T. Pseudomonas juntendi sp. nov., isolated from patients in Japan and Myanmar. Int J Syst Evol Microbiol., 69 (11), 3377-3384, 2019 |
| 6 | Hishinuma T, Tada T, Uchida H, Shimojima M, Kirikae T. A novel VIM-type metallo-β-lactamase variant, VIM-60, with increased fourth-generation cephalosporin-hydrolyzing activities in Pseudomonas aeruginosa clinical isolates in Japan. Antimicrob Agents Chemother., 63(6), 2019 |
| 7 | Tada T, Hishinuma T, Watanabe S, Uchida H, Tohya M, Kuwahara-Arai K, Mya S, Zan KN, Kirikae T, Tin HH. Molecular characterization of multidrug-resistant Pseudomonas aeruginosa isolates in hospitals in Myanmar. Antimicrob Agents Chemother., 2019 Apr 25;63(5). |
| 8 | Mori T, Hirai M, Mita T. See-through observation of malaria parasite behaviors in the mosquito vector. Scientific Reports. 2019; 9:1768 doi: 10.1038/s41598-019-38529-3. |
| 9 | Yamamoto T, Yatsushiro S, Hashimoto M, Kajimoto K, Ido Y, Abe K, Sofue Y, Nogami T, Hayashi T, Nagatomi K, Minakawa N, Oka H, Mita T, Kataoka M. Development of a highly sensitive, quantitative, and rapid detection system for Plasmodium falciparum-infected red blood cells using a fluorescent blue-ray optical system. Biosensors and Bioelectronics. 2019; 132:375-81 |
| 10 | Tateishi K, Fujihashi K, Yamamoto N, Hasegawa H, Ainai A, Sato K, Iho S, Yamamoto S, Maeyama JI, Odagiri T, Asanuma H. CpG ODN G9.1 as a novel nasal ODN adjuvant elicits complete protection from influenza virus infection without causing inflammatory immune responses. Vaccine. 2019 Aug 23;37(36):5382-5389. |
主な研究業績（2018年）
| 1 | Lu YJ, Sasaki T, Kuwahara-Arai K, Uehara Y, Hiramatsu K: Development of new application for comprehensive viability analysis based on microbiome analysis by next-generation sequencing: insights into staphylococcal carriage in human nasal cavities. Appl Environ Microbiol. pii: AEM.00517-18. doi:10.1128/AEM.00517-18, 2018 [Epub ahead of print] |
| 2 | Uehara Y, Mori M, Tauchi M, Nishimura S, Sakurai S, Murai T, Okazaki K, Kinoshita K, Horikoshi Y, Hiramatsu K: First report on USA300 outbreak in a neonatal intensive care unit detected by polymerase chain reaction-based open reading frame typing in Japan. J Infect Chemother 2018 Dec 27. pii: S1341-321X(18)30473-2. doi: 10.1016/j.jiac.2018.12.002. [Epub ahead of print] |
| 3 | Murai T, Okazaki K, Kinoshita K, Uehara Y, Zuo H, Lu Y, Ono Y, Sasaki T, Hiramatsu K, Horikoshi Y: Comparison of USA300 with non-USA300 methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit. Int J Infect Dis. S1201-9712:34599-5, 2018. [Epub ahead of print] |
| 4 | Hishinuma T, Tada T, Kuwahara-Arai K, Yamamoto N, Shimojima M, Kirikae T: Spread of GES-5 carbapenemase-producing Pseudomonas aeruginosa clinical isolates in Japan due to clonal expansion of ST235. PLoS One., 2018; 13:(11): e0207134, eCollection 2018. . |
| 5 | Tada T, Uechi K, Nakasone I, Nakamatsu M, Satou K, Hirano T, Kirikae T, Fujita J: Emergence of IncX4 plasmids encoding mcr-1 in a clinical isolate of Klebsiella pneumoniae in Japan. Int J Infect Dis., 2018; 75: 98-100. |
| 6 | Mita T, Hombhanje F, Takahashi N, Sekihara M, Yamauchi M, Tsukahara T, Kaneko A, Endo H, Ohashi J. Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea. Scientific reports. 2018;8. |
| 7 | Ikeda M, Kaneko M, Tachibana SI, Balikagala B, Sakurai-Yatsushiro M, Yatsushiro S, Takahashi N, Yamauchi M, Sekihara M, Hashimoto M, Katuro OT, Olia A, Obwoya PS, Auma MA, Anywar DA, Odongo-Aginya EI, Okello-Onen J, Hirai M, Ohashi J, Palacpac NMQ, Kataoka M, Tsuboi T, Kimura E, Horii T, Mita T. Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016. Emerging infectious diseases. 2018;24:718-26. |
| 8 | Tsuji R, Yamamoto N, Yamada S, Fujii T, Yamamoto N, Kanauchi O. Induction of anti-viral genes mediated by humoral factors upon stimulation with Lactococcus lactis strain plasma results in repression of dengue virus replication in vitro. Antiviral Res. 2018 Dec;160:101-108. doi: 10.1016/j.antiviral.2018.10.020. |
| 9 | Matsuo M, Yamamoto N, Hishinuma T, Hiramatsu K. Identification of a novel gene associated with high-level β-lactam resistance in heterogeneous vancomycin-intermediate Staphylococcus aureus strain Mu3 and methicillin-resistant S. aureus strain N315. Antimicrob Agents Chemother. 2018 Nov 19. pii: AAC.00712-18. |
| 10 | Matsuo M, Hiramatsu M, Singh M, Sasaki T, Hishinuma T, Yamamoto N, Morimoto Y, Kirikae T, Hiramatsu K. Genetic and transcriptomic analyses of ciprofloxacin-tolerant Staphylococcus aureus isolated by the Replica Plating Tolerance Isolation System (REPTIS). Antimicrob Agents Chemother. 2018 Dec 3. pii: AAC.02019-18. |
主な研究業績（2017年）
| 1 | Singh M, Matsuo M, Sasaki T, Morimoto Y, Hishinuma T, Hiramatsu K. In Vitro Tolerance of A Drug-Naïve Staphylococcus aureus FDA209P towards Vancomycin. Antimicrob Agents Chemother. 24;61(2). 2017. |
| 2 | Kikuchi K, Matsuda M, Iguchi S, Mizutani T, Hiramatsu 2, Tega-Ishii M, Sansaka K, Negishi K, Shimada K, Umemura J, Notake S, Yanagisawa H, Takahashi H, Yabusaki R, Araoka H, Yoneyama A. Potential Impact of Rapid Blood Culture Testing for Gram-Positive Bacteremia in Japan with the Verigene Gram-Positive Blood Culture Test. Can J Infect Dis Med Microbiol. :4896791. 2017. |
| 3 | Tan XE, Neoh HM, Looi ML, Chin SF, Cui L, Hiramatsu K, Hussin S, Jamal R. Activated ADI pathway: the initiator of intermediate vancomycin resistance in Staphylococcus aureus. Can J Microbiol. 63(3):260-264. 2017. |
| 4 | Ishikawa D, Sasaki T, Osada T, Kuwahara-Arai K, Haga K, Shibuya T, Hiramatsu K, Watanabe S. Changes in Intestinal Microbiota Following Combination Therapy with Fecal Microbial Transplantation and Antibiotics for Ulcerative Colitis. Inflammatory Bowel Diseases. 23(1):116-125. 2017. |
| 5 | Sugiyama H, Yoshida I, Ueki M, Tanabe K, Manaka A, Hiramatsu K. In vitro antibacterial activity of α-methoxyimino acylide derivatives against macrolide-resistant pathogens and mutation analysis in 23S rRNA. J Antibiot (Tokyo). 70(3):264-271. 2017. |
| 6 | Miyoshi N, Isogai M, Hiramatsu K, Sasaki T. Activity of tick antimicrobial peptide from Ixodes persulcatus (persulcatusin) against cell membranes of drug-resistant Staphylococcus aureus. J Antibiot. 70(2):142-146. 2017. |
| 7 | Tanaka Y, Sato Y, Sasaki T. Feline coronavirus replication is affected by both cyclophilin A and cyclophilin B. J Gen Virol. 98(2):190-200. 2017. |
| 8 | Balikagala B, Mita T, Ikeda M, Sakurai M, Yatsushiro S, Takahashi N, Tachibana SI, Auma M, Ntege EH, Ito D, Takashima E, Palacpac NM, Egwang TG, Onen JO, Kataoka M, Kimura E, Horii T, Tsuboi T. Absence of in vivo selection for K13 mutations after artemether-lumefantrine treatment in Uganda. Malar J. 16(1):23. 2017. |
| 9 | Nakaminami H, Ito T, Han X, Ito A, Matsuo M, Uehara Y, Baba T, Hiramatsu K, Noguchi N. First report of sasX-positive methicillin-resistant Staphylococcus aureus in Japan. FEMS Microbiol Lett. 1;364(16). 2017 |
| 10 | Raulinaitis V, Tossavainen H, Aitio O, Juuti JT, Hiramatsu K, Kontinen V, Permi P. Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family. Sci Rep. 20;7(1):6020. 2017 |
主な研究業績（2016年）
| 1 | Mita T, Culleton R, Takahashi N, Nakamura M, Tsukahara T, Hunja CW, Win ZZ, Htike WW, Marma AS, Dysoley L, Ndounga M, Dzodzomenyo M, Akhwale WS, Kobayashi J, Uemura H, Kaneko A, Hombhanje F, Ferreira MU, Bjorkman A, Endo H, Ohashi J. Little Polymorphism at the K13 Propeller Locus in Worldwide Plasmodium falciparum Populations Prior to the Introduction of Artemisinin Combination Therapies. Antimicrob Agents Chemother. 2016 60(6):3340-7. |
| 2 | Katayama Y, Sekine M, Hishinuma T, Aiba Y, Hiramatsu K. Complete reconstitution of the VISA phenotype of Mu50 in Vancomycin-Susceptible Staphylococcus aureus. Antimicrob Agents Chemother. 2016 60(6).3730-3743. |
| 3 | Mita T, Tachibana S, Hashimoto M, Hirai M. Plasmodium falciparum kelch 13: a potential molecular marker for tackling artemisinin-resistant malaria parasites. Expert Rev Anti Infect Ther. 2016 14(1):125-35. |
| 4 | Hishinuma T, Katayama Y, Matsuo M, Sasaki T, Hiramatsu K. Complete Genome Sequence of Vancomycin-Intermediate Staphylococcus aureus Strain MI (HIP5827). Genome Announc. 2016 17;4(2) pii: e00123-16. |
| 5 | Murakami T, Hu Z, Tamura H, Nagaoka I. Release mechanism of high mobility group nucleosome binding protein 1 from lipopolysaccharide-stimulated macrophages. Mol Med Rep 2016 13: 3115-3120. |
| 6 | Hashimoto M, Nara T, Mita T, Mikoshiba K. Morpholino antisense oligo inhibits trans-splicing of pre-inositol 1,4,5-trisphosphate receptor mRNA of Trypanosoma cruzi and suppresses parasite growth and infectivity. Parasitol Int. 2016 65:175-179. |
| 7 | Takamiya S, Mita T. Large-scale purification of active liquid-cultured Caenorhabditis elegans using a modified Baermann apparatus. Parasitol Int. 2016 65(5 Pt B):580-583. |
| 8 | Iguchi S, Mizutani T, Hiramatsu K, Kikuchi K. Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination. PLoS One. 2016 16;11(5):e0155512. |
| 9 | Yatsushiro S, Yamamoto T, Yamamura S, Abe K, Obana E, Nogami T, Hayashi T, Sesei T, Oka H, Okello-Onen J, Odongo-Aginya EI, Alai MA, Olia A, Anywar D, Sakurai M, Palacpac NM, Mita T, Horii T, Baba Y, Kataoka M. Application of a cell microarray chip system for accurate, highly sensitive, and rapid diagnosis for malaria in Uganda. Scientific reports. 2016 6:30136. |
| 10 | Honma H, Niikura M, Kobayashi F, Horii T, Mita T, Endo H, Hirai M. Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase delta. Scientific reports. 2016 6:36971. |
英文原著（2015年）
| 1 | Matsuo M, Hishinuma T, Katayama Y, Hiramatsu K. A mutaion of RNA polymerase β' subunit (RpoC) converts heterogeneously vancomycin intermediate S. aureus (hVISA) into 'slow-VISA' (sVISA). Antimicrob Agents Chemother. 59(7):4215-25. 2015. |
| 2 | Yoshihara N, Ueno T, Takagi A, Oliva Trejo JA, Haruna K, Suga Y, Komatsu M, Tanaka K, Ikeda S. The significant role of autophagy in the granular layer in normal skin differentiation and hair growth. Arch Dermatol Res. 307(2):159-69. 2015. |
| 3 | Takenaka S-I, Kaieda S, Kawayama T, Matsuoka M, Kaku Y, Kinoshita T, Sakazaki Y, Okamoto M, Tominaga M, Kanesaki K, Chiba A, Miyake S, Ida H, Hoshino T. IL-38: A new factor in rheumatoid arthritis. Biochem Biophys Rep. 4:386-391 2015. |
| 4 | Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S. ICOS promotes group 2 innate lymphoid cell activation in lungs. Biochem Biophys Res Commun. 463(4):739-45 2015. |
| 5 | Hashimoto M, Nara T, Enomoto M, Kurebayashi N, Yoshida M, Sakurai T, Mita T, Mikoshiba K. A dominant negative form of inositol 1,4,5-trisphosphate receptor induces metacyclogenesis and increases mitochondrial density in Trypanosoma cruzi. Biochem Biophys Res Commun. 466:475-480. 2015. |
| 6 | Ekyalongo RC, Nakayama H, Kina K, Kaga N, Iwabuchi K. Organization and functions of glycolipid-enriched microdomains in phagocytes. Biochim Biophys Acta, 1851:90-7. 2015. |
| 7 | Fudo S*, Yamamoto N*, Nukaga M, Odagiri T, Tashiro M, Neya S, Hoshino T (*These authors contributed equally to this work). Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase. Bioorg Med Chem. 1;23(17):5466-75. 2015. |
| 8 | Tanaka Y, Sasaki T, Matsuda R, Uematsu Y, Yamaguchi T. Molecular epidemiological study of feline coronavirus strains in Japan using RT-PCR targeting nsp14 gene. BMC Veterinary Research 11:57. 2015. |
| 9 | Sugimura T*, Takahashi H*, Jounai K, Ohshio K, Kanayama M, Tazumi K, Tanihata Y, Miura Y, Fujiwara D, Yamamoto N*(*These authors contributed equally to this work). Effects of oral intake of pDC-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus. Br J Nutr. 14;114(5):727-33. 2015. |
| 10 | Croxford JL, Miyake S. Immunoregulation of multiple sclerosis by gut environmental factors. Clin Exp Neuroimmunol. 6(4):362–369 2015. |
| 11 | Dong H, Franklin NA, Ritchea SB, Yagita H, Glennie MJ, Bullock TN. CD70 and IFN-1 selectively induce Eomesdermin or T-bet and synergize to promote CD8+ T-cell responses. Eur J Immunol. 45: 3289-3301 2015. |
| 12 | Iwabuchi K. Involvement of glycosphingolipid-enriched lipid rafts in inflammatory responses. Front Biosci (Landmark Ed). 20:325-34, 2015 2015. |
| 13 | Tsukahara T, Ogura S, Sugahara T, Sekihara M, Furusawa T, Kondo N, Mita T, Endo H, Hombhanje F. The Choice of Healthcare Providers for Febrile Children after Introducing Non-professional Health Workers in a Malaria Endemic Area in Papua New Guinea. Front Public Health. 2015;3:275. 2015. |
| 14 | Singh M, Sasaki T, Matsuo M, Morimoto Y, Aiba Y, Hiramatsu K. Complete Genome Sequence of a Drug-naive Classical Staphylococcus aureus Strain FDA209P. Genome Announc. 12;3(6). 2015. |
| 15 | Sasaki T, Tsubakishita S, Kuwahara-Arai K, Mastuo M, Lu YJ, Tanaka Y, Hiramatsu K. Complete Genome Sequence of a Methicillin-Resistant Staphylococcus schleiferi Strain TSCC54, of Canine Origin. Genome Announc. 29;3(5). 2015. |
| 16 | Iwabuchi K, Masuda H, Kaga N, Nakayama H, Matsumoto R, Iwahara C, Yoshizaki F, Tamaki Y, Kobayashi T, Hayakawa T, Ishii K, Yanagida M, Ogawa H, Takamori K. Properties and Functions of Lactosylceramide from Mouse Neutrophils. Glycobiology. 25: 655-68, 2015 2015. |
| 17 | Jesus M, Rodriguez AE, Yagita H, Ostroff GR, Mantis NJ. Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer’s patches. Immunol Lett. 168: 64-72. 2015. |
| 18 | Tsutsui-Takeuchi M, Ushio H, Fukuda M, Yamada T, Niyonsaba F, Okumura K, Ogawa H, Ikeda S. Roles of retinoic acid-inducible gene-I-like receptors (RLRs), Toll-like receptor (TLR) 3 and 2'-5' oligoadenylate synthetase as viral recognition receptors on human mast cells in response to viral infection. Immunol Res. 2015 61(3):240-9. 2015. |
| 19 | Tajiri H, Nishi J, Ushijima K, Shimizu T, Ishige T, Shimizu M, Tanaka H, Brooks S. A role for fosfomycin treatment in children for prevention of haemolytic-uraemic syndrome accompanying Shiga toxin-producing Escherichia coli infection. Int J Antimicrob Agents 46:586-9. 2015. |
| 20 | Morimoto Y, Baba T, Sasaki T, Hiramatsu K. Apigenin as an Anti-Quinolone-Resistance Antibiotic. Int J Antimicrob Agents. 46(6):666-73. 2015. |
| 21 | Murate M, Abe M, Kasahara K, Iwabuchi K, Umeda M, Kobayashi T. Transbilayer lipid distribution in nano scale. J Cell Sci. 128:1627-3820. 2015. |
| 22 | Smithrithee R, Niyonsaba F, Kiatsurayanon C, Ushio H, Ikeda S, Okumura K, Ogawa H. Human β-defensin-3 increases the expression of interleukin-37 through CCR6 in human keratinocytes. J Dermatol Sci. 77(1):46-53. 2015. |
| 23 | Yamazaki S, Nakano N, Honjo A, Hara M, Maeda K, Nishiyama C, Kitaura J, Ohtsuka Y, Okumura K, Ogawa H, Shimizu T. The Transcription Factor Ehf Is Involved in TGF-beta-Induced Suppression of Fc epsilon RI and c-Kit Expression and Fc epsilon RI-Mediated Activation in Mast Cells. J Immunol 195:3427-35. 2015. |
| 24 | Uehara Y, Ito T, Ogawa Y, Hirotaki S, Shoji T, Tame T, Horikoshi Y, Hiramatsu K. Molecular epidemiologic study of community-associated methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin gene among family members in Japan. J Infect Chemother 21: 700-702. 2015. |
| 25 | Chiricozzi E, Ciampa MG, Brasile G, Compostella F, Prinetti A, Nakayama H, Ekyalongo RC, Iwabuchi K, Sonnino S, Mauri L. Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells. J Lipid Res, 56:129-41. 2015. |
| 26 | Nara T. Current situation of Chagas disease in non-endemic countries. Juntendo Med J 61: 389-395. 2015. |
| 27 | Yamamoto N. An overview of Ebola virus disease: History, pathogenesis, and treatment. Juntendo Medical Journal, 61(4): 350-472. 2015. |
| 28 | Mita T. Current Research Topics in Tropical Diseases; Towards Successful Control and Elimination. Juntendo Medical Journal. 61(4):358-9. 2015. |
| 29 | Hirai M, Mita T. Challenging Malaria Control. Juntendo Medical Journal. 61(4):370-7. 2015. |
| 30 | Iwabuchi K, Nakayama H, Oizumi A, Suga Y, Ogawa H, Takamori K. Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. Mediators Inflamm. 2015:120748. 2015. |
| 31 | Matsunaga N, Hisata K, Shimizu T. An investigation into the vancomycin concentration in the cerebrospinal fluid due to vancomycin intraventricular administration in newborns: a study of 13 cases. Medicine 94:e922. 2015. |
| 32 | Ohsawa H, Baba T, Enami J, Hiramatsu K. Successful selection of an infection-protective anti-Staphylococcus aureus monoclonal antibody and its protective activity in murine infection models. Microbiol Immunol. 59:183-92 2015. |
| 33 | Mita T, Jombart T. Patterns and dynamics of genetic diversity in Plasmodium falciparum: what past human migrations tell us about malaria. Parasitol Int. 64(3):238-43. 2015. |
| 34 | Tanabe K, Zollner G, Vaughan JA, Sattabongkot J, Khuntirat B, Honma H, Mita T, Tsuboi T, Coleman R. Plasmodium falciparum: genetic diversity and complexity of infections in an isolated village in western Thailand. Parasitol Int. 64(3):260-6. 2015. |
| 35 | Murai K, Culleton R, Hisaoka T, Endo H, Mita T. Global distribution of polymorphisms associated with delayed Plasmodium falciparum parasite clearance following artemisinin treatment: genotyping of archive blood samples. Parasitol Int. 64(3):267-73. 2015. |
| 36 | Suzuki M, Saito N, Naritaka N, Nakano S, Minowa K, Honda Y, Ohtsuka Y, Yamataka A, Shimizu T. Scoring system for the prediction of severe acute pancreatitis in children. Pediatr Int 57:113-8. 2015. |
| 37 | Hashimoto M, Morales J, Uemura H, Mikoshiba K, Nara T. A novel method for inducing amastigote-to-trypomastigote transformation in vitro in Trypanosoma cruzi reveals the importance of inositol 1,4,5-trisphosphate receptor. PLoS One. 10:e0135726. 2015. |
| 38 | Hasegawa T, Sakamoto A, Wada A, Fukai T, Iida H, Ikeda S. Keratinocyte progenitor cells reside in human subcutaneous adipose tissue. PLoS One. 10(2):e0118402. 2015. |
| 39 | Miyake S, Kim S, Suda W, Oshima K, Nakamura M, Matsuoka T, Chihara N, Tomita A, Sato W, Kim S, Morita H, Hattori M, Yamamura T. Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters. PLoS One. 10(9):e0137429 2015. |
| 40 | Ishii K, Tabuchi F, Matsuo M, Tatsuno K, Sato T, Okazaki M, Hamamoto H, Matsumoto Y, Kaito C, Aoyagi T, Hiramatsu K, Kaku M, Moriya K, Sekimizu K. Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro mutagenesis. Sci Rep. 25;5:17092. 2015. |
| 41 | Hasegawa T, Ikeda S. Adipose-derived stromal/stem cells as potential source of skin regeneration. Stem Cell Transl Investig. 2:e787 2015. |
| 42 | Tanaka Y, Sato Y, Takahashi D, Matsumoto H, Sasaki T. Treatment of a case of feline infectious peritonitis with cyclosporin A. Vet Rec Case Rep. 3:e000134. 2015. |
| 43 | Hiramatsu K, Morimoto Y. Farewell Lecture: Future Chemotherapy Preventing Emergence of Multi-Antibiotic Resistance. Juntendo Med J. 61(3) 249-256. 2015. |
英文原著（2014年）
| 1 | Hiramatsu K, Katayama Y, Matsuo M, Aiba Y, Saito M, Hishinuma T, Iwamoto A. Vancomycin-intermediate resistance in Staphylococcus aureus. J Glob Antimicrob Resist. 2014 Dec;2(4) :213–224 |
| 2 | Hiramatsu K, Katayama Y, Matsuo M, Sasaki T, Morimoto Y, Sekiguchi A, Baba T. Multi-Drug-Resistant Staphylococcus aureus and Future Chemotherapy. J Infect Chemother. 2014 Oct;20(10):593-601. |
| 3 | Honma H, Hirai M, Nakamura S, Hakimi H, Kawazu S, Palacpac NM, Hisaeda H, Matsuoka H, Kawai S, Endo H, Yasunaga T, Ohashi J, Mita T, Horii T, Furusawa M, Tanabe K. Generation of rodent malaria parasites with a high mutation rate by destructing proofreading activity of DNA polymerase δ. DNA Res. 2014 Aug;21(4):439-46. |
| 4 | Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I. Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism. PLoS One. 2014 Jan 16;9(1):e85765. |
| 5 | Ito T, Kuwahara-Arai K, Katayama Y, Uehara Y, Han X, Kondo Y, Hiramatsu K. Staphylococcal Cassette Chromosome mec (SCCmec) analysis of MRSA. Methods Mol Biol. 2014;1085:131-48. |
| 6 | Mita T, Ohashi J, Venkatesan M, Marma AS, Nakamura M, Plowe CV, Tanabe K. Ordered accumulation of mutations conferring resistance to sulfadoxine-pyrimethamine in the Plasmodium falciparum parasite. J Infect Dis. 2014 Jan 1;209(1):130-9. |
| 7 | Nakao A, Ito T, Han X, Lu YJ, Hisata K, Tsujiwaki A, Matsunaga N, Komatsu M, Hiramatsu K, Shimizu T. Intestinal carriage of methicillin-resistant Staphylococcus aureus in nasal MRSA carriers hospitalized in the neonatal intensive care unit. Antimicrob Resist Infect Control. 2014 Apr;3:14. |
| 8 | Saito M, Katayama Y, Hishinuma T, Iwamoto A, Aiba Y, Kuwahara-Arai K, Cui L, Matsuo M, Aritaka N, Hiramatsu K. Slow VISA' (sVISA), a novel phenotype of vancomycin resistance, obtained in vitro from hVISA strain Mu3. Antimicrob Agents Chemother. 2014 Sep;58(9):5024-35. |
| 9 | Takai T, Chen X, Xie Y, Vu AT, Le TA, Kinoshita H, Kawasaki J, Kamijo S, Hara M, Ushio H, Baba T, Hiramatsu K, Ikeda S, Ogawa H, Okumura K. TSLP expression induced via Toll-like receptor pathways in human keratinocytes. Methods Enzymol. 2014;535:371-87. |
英文原著（2013年）
| 1 | Aiba Y, Katayama Y, Hishinuma T, Murakami-Kuroda H, Cui L, Hiramatsu K. Mutation of RNA polymerase β-subunit gene promotes heterogeneous-to-homogeneous conversion of β-lactam resistance in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Oct;57(10):4861-71. |
| 2 | Hiramatsu K, Ito T, Tsubakishita S, Sasaki T, Takeuchi F, Morimoto Y, Katayama Y, Matsuo M, Kuwahara-Arai K, Hishinuma T, Baba T. Genomic Basis for Methicillin Resistance in Staphylococcus aureus1 Infect Chemother. 2013 Jun;45(2):117-36. Review. |
| 3 | Hunja CW, Unger H, Ferreira PE, Lumsden R, Morris S, Aman R, Alexander C, Mita T, Culleton R. Travellers as sentinels: Assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in Plasmodium falciparum using malaria cases imported into Scotland. Int J Parasitol. 2013 Oct;43(11):885-9. |
| 4 | Kaito C, Saito Y, Ikuo M, Omae Y, Mao H, Nagano G, Fujiyuki T, Numata S, Han X, Obata K, Hasegawa S, Yamaguchi H, Inokuchi K, Ito T, Hiramatsu K, Sekimizu K. Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence. PLoS Pathog. 2013;9(4):e1003269. |
| 5 | Khattak AA, Venkatesan M, Jacob CG, Artimovich EM, Nadeem MF, Nighat F, Hombhanje F, Mita T, Malik SA, Plowe CV. A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan. Malar J. 2013 Aug 29;12:300. |
| 6 | Lulitanond A, Ito T, Li S, Han X, Ma XX, Engchanil C, Chanawong A, Wilailuckana C, Jiwakanon N, Hiramatsu K. ST9 MRSA strains carrying a variant of type IX SCCmec identified in the Thai community. BMC Infect Dis. 2013 May;13:214. |
| 7 | Matsuo M, Cui L, Kim J, Hiramatsu K. Comprehensive identification of mutations responsible for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA)-to-VISA conversion in laboratory-generated VISA strains derived from hVISA clinical strain Mu3. Antimicrob Agents Chemother. 2013 Dec;57(12):5843-53. |
| 8 | Notake S, Matsuda M, Tamai K, Yanagisawa H, Hiramatsu K, Kikuchi K. Detection of IMP metallo-β-lactamase in carbapenem-non-susceptible Enterobacteriaceae and glucose non-fermenting Gram-negative rods by immunochromatography assay. J Clin Microbiol. 2013 Jun;51(6):1762-8. |
| 9 | Ohkushi D, Uehara Y, Iwamoto A, Misawa S, Kondo S, Shimizu K, Hori S, Hiramatsu K. An effective active surveillance method for controlling nosocomial MRSA transmission in a Japanese hospital. J Infect Chemother. 2013 Oct;19(5):871-5. |
| 10 | Tanabe K, Jombart T, Horibe S, Palacpac NM, Honma H, Tachibana S, Nakamura M, Horii T, Kishino H, Mita T. Plasmodium falciparum mitochondrial genetic diversity exhibits isolation-by-distance patterns supporting a sub-Saharan African origin. Mitochondrion. 2013 Nov;13(6):630-6. |
| 11 | Tomoyasu T, Imaki H, Masuda S, Okamoto A, Kim H, Waite RD, Whiley RA, Kikuchi K, Hiramatsu K, Tabata A, Nagamune H. LacR mutations are frequently observed in Streptococcus intermedius and are responsible for increased intermedilysin production and virulence. Infect Immun. 2013 Sep;81(9):3276-86. |
| 12 | Uehara Y, Kuwahara-Arai K, Hori S, Kikuchi K, Yanai M, Hiramatsu K. Investigation of nasal meticillin-resistant Staphylococcus aureus carriage in a haemodialysis clinic in Japan. J Hosp Infect. 2013 May;84(1):81-4. |
| 13 | Zhang M, Ito T, Li S, Misawa S, Kondo S, Miida T, Ohsaka A, Hiramatsu K. Analysis of Staphylococcal Cassette Chromosome mec in BD GeneOhm™ MRSA Assay negative strains. Antimicrob Agents Chemother. 2013 Jun;57(6):2890-1. |
英文原著（2012年）
| 1 | Hashimoto H, Morales J, Fukai Y, Suzuki S, Takamiya S, Tsubouchi A, Inoue S, Inoue M, Kita K, Harada S, Tanaka A, Aoki T, Nara T. Critical importance of the de novo pyrimidine biosynthesis pathway for Trypanosoma cruzi growth in the mammalian host cell cytoplasm. Biochem Biophys Res Commun. Jan 20;417(3):1002-6. 2012 |
| 2 | Kayama H, Ueda Y, Sawa Y, Jeon SG, Ma JS, Okumura R, Kubo A, Ishii M, Okazaki T, Murakami M, Yamamoto M, Yagita H, Takeda K. Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis. Proc Natl Acad Sci U S A. Mar 27;109(13):5010-5. 2012 |
| 3 | Kitamura N, Yokoyama H, Yashiro T, Nakano N, Nishiyama M, Kanada S, Fukai T, Hara M, Ikeda S, Ogawa H, Okumura K, Nishiyama C. Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells. J Allergy Clin Immunol. Mar;129(3):814-824.e6. 2012 |
| 4 | Miyano G, Takahashi T, Takahashi T, Lane GJ, Kato Y, Okazaki T, Yamataka A. An unusual foreign body in an inguinal hernia sac: case report and literature review. Afr J Paediatr Surg. Jan-Apr;9(1):66-7. 2012 |
| 5 | Nakamura H, Koga H, Wada M, Miyano G, Dizon R, Kato Y, Lane GJ, Okazaki T, Yamataka A. Reappraising the portoenterostomy procedure according to sound physiologic/anatomic principles enhances postoperative jaundice clearance in biliary atresia. Pediatr Surg Int. Feb;28(2):205-9. 2012 |
| 6 | Nakamura H, Okazaki T, Koga H, Lane GJ, Yamataka A. Congenital brachioesophagus with secondary intrathoracic stomach associated with rachischisis described as "serpentine-like syndrome": a case report and literature review. Pediatr Surg Int. Jan;28(1):63-6. 2012 |
| 7 | Nara T, Hashimoto M, Hirawake H, Liao CW, Fukai Y, Suzuki S, Tsubouchi A, Morales J, Takamiya S, Fujimura T, Taka H, Mineki R, Fan CK, Inaoka K, Inoue M, Tanaka A, Harada S, Kita K, Aoki T. Molecular interaction of the first 3 enzymes of the de novo pyrimidine biosynthetic pathway of Trypanosoma cruzi. Biochem Biophys Res Commun. Feb 3;418(1):140-3. 2012 |
| 8 | Nishina T, Komazawa-Sakon S, Yanaka S, Piao X, Zheng DM, Piao JH, Kojima Y, Yamashina S, Sano E, Putoczki T, Doi T, Ueno T, Ezaki J, Ushio H, Ernst M, Tsumoto K, Okumura K, Nakano H. Interleukin-11 links oxidative stress and compensatory proliferation. Sci Signal. Jan17;5(207):ra5. 2012 |
| 9 | Nishioka J, Iwahara C, Kawasaki M, Yoshizaki F, Nakayama H, Takamori K, Ogawa H, Iwabuchi K. Di-(2-ethylhexyl) phthalate induces production of inflammatory molecules in human macrophages. Inflamm Res. Jan;61(1):69-78. 2012 |
| 10 | Ochi T, Okazaki T, Miyano G, Lane GJ, Yamataka A. A comparison of clinical protocols for assessing postoperative fecal continence in anorectal malformation. Pediatr Surg Int. Jan;28(1):1-4. 2012 |
| 11 | Ohtsuka Y, Ikegami T, Izumi H, Namura M, Ikeda T, Ikuse T, Baba Y, Kudo T, Suzuki R, Shimizu T. Effects of Bifidobacterium breve on inflammatory gene expression in neonatal and weaning rat intestine. Pediatr Res. Jan;71(1):46-53. 2012 |
| 12 | Oka F, Naito T, Oike M, Imai R, Saita M, Inui A, Mitsuhashi K, Isonuma H, Shimbo T. Correlation between HIV disease and lipid metabolism in antiretroviral-naïve HIV-infected patients in Japan. J Infect Chemother. Feb;18(1):17-21. 2012 |
| 13 | Okumura A, Tsuji T, Kubota T, Ando N, Kobayashi S, Kato T, Natsume J, Hayakawa F, Shimizu T. Acute encephalopathy with 2009 pandemic flu: Comparison with seasonal flu. Brain Dev. Jan;34(1):13-9. 2012 |
| 14 | Seo S, Takahashi T, Marusasa T, Kusafuka J, Koga H, Halibieke A, Lane GJ, Okazaki T, Yamataka A. Management of inguinal hernia in children can be enhanced by closer follow-up by consultant pediatric surgeons. Pediatr Surg Int. Jan;28(1):33-6. 2012 |
| 15 | Sugasawa Y, Yamaguchi K, Kumakura S, Murakami T, Suzuki K, Nagaoka I, Inada E. Effects of sevoflurane and propofol on pulmonary inflammatory responses dusing lung resection. J Anesth. Feb;26(1):62-9. 2012 |
| 16 | Yanagita H, Yamamoto N, Fuji H, Liu X, Ogata M, Yokota M, Takaku H, Hasegawa H, Odagiri T, Tashiro M, Hoshino T. Mechanism of Drug Resistance of Hemagglutinin of Influenza Virus and Potent Scaffolds Inhibiting Its Function. ACS Chem Biol. 2012 Mar 16;7(3):552-62. 2012 |
英文原著（2011年）
| 1 | Aihara M, Hasegawa T, Okuyama Y, Hiruma M, Ikeda S. Langerhans cell histiocytosis treated with narrow-band ultraviolet B. J Dermatol. Feb;38(2):151-4. 2011 |
| 2 | Arii R, Koga H, Arakawa A, Miyahara K, Lane GJ, Okazaki T, Urao M, Yamataka A. How valuable is ductal plate malformation as a predictor of clinical course in postoperative biliary atresia patients? Pediatr Surg Int. Mar;27(3):275-7. 2011 |
| 3 | Asaoka D, Nagahara A, Oguro M, Mori H, Nakae K, Izumi Y, Osada T, Hojo M, Otaka M, Watanabe S. Establishment of a reflux esophago-laryngitis model in rats. Dig Dis Sci.56,1299-1308, 2011 |
| 4 | Aung G, Niyonsaba F, Ushio H, Hoq MI, Ikeda S, Ogawa H, Okumura K. A neuroendocrine antimicrobial peptide, catestatin, stimulates interleukin-8 production from human keratinocytes via activation of mitogen-activated protein kinases. J Dermatol Sci. 2011 Feb;61(2):142-4. 2011 |
| 5 | Aung G, Niyonsaba F, Ushio H, Ikeda S, Okumura K, Ogawa H. Elafin and secretory leukocyte protease inhibitor stimulate the production of cytokines and chemokines by human keratinocytes via MAPK/ERK and NF-κB activation. J Dermatol Sci. 2011 Aug;63(2):128-31. 2011 |
| 6 | Aung G, Niyonsaba F, Ushio H, Kajiwara N, Saito H, Ikeda S, Ogawa H, Okumura K. Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. Immunology. 2011 Apr;132(4):527-39. 2011 |
| 7 | Beppu K, Osada T, Inoue K, Matsumoto K, Shibuya T, Sakamoto N, Kawabe M, Nagahara A, Ogihara T, Watanabe S. Intestinal involvement in Wegener's granulomatosis diagnosed and followed up by double balloon enteroscopy. Intern Med. 50(3):219-22, 2011 |
| 8 | Beppu K, Osada T, Nagahara A, Matsumoto K, Shibuya T, Sakamoto N, Otaka M, Terai T, Ogihara T, Watanabe S. Relationship between endoscopic finding and clinical severity in ischemic colitis. Intern Med. 50(20):2263-7. 2011 |
| 9 | Charbonney E, Speight P, Masszi A, Nakano H, Kapus A. beta-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition. Mol Biol Cell. Dec;22(23):4472-85. 2011 |
| 10 | Ding Q, Yeung M, Camirand G, Zeng Q, Akiba H, Yagita H, Chalasani G, Sayegh MH, Najafian N, Rothstein DM. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest. Sep;121(9):3645-56. 2011 |
| 11 | Donaldoson DS, Kobayashi A, Ohno H, Yagita H, Williams IR, Mabbott NA. M cell-depletion blocks oral prion disease pathogenesis. Mucosal Immunol. Mar;5(2):216-25. 2012 |
| 12 | Fujii T, Hou R, Sato-Hayashizaki A, Obata M, Ohtsuji M, Ikeda K, Mitsui K, Kodera Y, Shirai T, Hirose S, Nishimura H. Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: Implication of epistatic effects of Fcgr2b and Slam family genes. Eur J Immunol. Aug;41(8):2333-40. 2011 |
| 13 | Funakushi N, Yamaguchi T, Jiang J, Imamura S, Kuhara T, Suto H, Ueki R, Kase Y, Kobayashi H, Ogawa H, Ikeda S. Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice. Arch Dermatol Res. Nov;303(9):659-67. 2011 |
| 14 | Goto S, Okazaki T, Koga H, Miyano G, Arakawa A, Yao T, Lane GJ, Yamataka A. Ectopic pancreas presenting as a submucosal gastric tumor: case report and literature review. Pediatr Surg Int. Jan;27(1):107-9. Review. 2011 |
| 15 | Higashiyama M, Ito T, Han X, Tanno A, Wada T, Funaoka Y, Yoshida Y, Mikita K, Ogawa T, Nishiyama J, Okusa Y, Kaku K, Hatada J, Hiramatsu K, Kawana A. Trial to control an outbreak of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus at a boarding school in Japan. Am J Infect Control. Dec;39(10):858-65. 2011 |
| 16 | Hirose K, Iwabuchi K, Shimada K, Kiyanagi T, Iwahara C, Nakayama H, Daida H. Different responses to oxidized low-density lipoproteins in human polarized macrophages. Lipids Health Dis. Jan 4;10:1. 2011 |
| 17 | Hirotaki S, Sasaki T, Kuwahara-Arai K, Hiramatsu K. Rapid and accurate identification of human associated staphylococci by multiplex PCR. J Clin Microbiol. Oct;49(10):3627-31. 2011 |
| 18 | Hirotsu M, Kikuchi K, Kusunoki T, Kase K, Ono N, Ikeda K. Comparison of bacterial examinations between eosinophilic and neutrophilic chronic rhinosinusitis with nasal polyps. Acta Otolaryngol. Sep;131(9):997-1001. 2011 |
| 19 | Hiruma A, Ikeda S, Terui T, Ozawa M, Hashimoto T, Yasumoto S, Nakayama J, Kubota Y, Iijima M, Sueki H, Matsumoto Y, Kato M, Akasaka E, Ikoma N, Mabuchi T, Tamiya S, Matsuyama T, Ozawa A, Inoko H, Oka A. A novel splicing variant of CADM2 as a protective transcript of psoriasis. Biochem Biophys Res Commun. Sep 9;412(4):626-32. 2011 |
| 20 | Hisata K, Ito T, Matsunaga N, Komatsu M, Jin J, Li S, Watanabe S, Shimizu T, Hiramatsu K. Dissemination of multiple MRSA clones among community-associated methicillin-resistant Staphylococcus aureus infections from Japanese children with impetigo. J Infect Chemother. Oct;17(5):609-21. 2011 |
| 21 | Hojo M, Ohkusa T, Tomeoku H, Koido S, Asaoka D, Nagahara A, Watanabe S. Corticotropin-releasing factor secretion from dendritic cells stimulated by commensal bacteria. World J Gastroenterol. Sep 21;17(35):4017-22, 2011 |
| 22 | Hongou H, Fu K, Ueyama H, Takahashi T, Takeda T, Miyazaki A, Watanabe S. Mallory-Weiss tear during gastric endoscopic submucosal dissection. World J Gastrointest Endosc. Jul 16;3(7):151-3. 2011 |
| 23 | Hosoda H, Tamura H, Kida S, Nagaoka I. Transcriptional regulation of mouse TREM-1 gene in RAW264.7 macrophage-like cells. Life Sci. Jul 18;89(3-4):115-22. 2011 |
| 24 | Inage E, Saito M, Saito Y, Takata O, Fujimura J, Yamataka A, Shimizu T. Contralateral pleural recurrence of adrenocortical carcinoma after surgical resection. Pediatr Int. Aug;53(4):600-3. 2011 |
| 25 | Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M. Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol 18,193,275-84. 2011 |
| 26 | Inami Y, Yamashina S, Izumi K, Ueno T, Tanida I, Ikejima K, Watanabe S. Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression. Biochem Biophys Res Commun. Sep 9;412(4):618-25. 2011 |
| 27 | Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S. CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice. J Hepatol. Jun;54(6):1195-204. 2011 |
| 28 | Itatsu T, Nagahara A, Hojo M, Miyazaki A, Murai T, Nakajima M, Watanabe S. Use of selective serotonin reuptake inhibitors and upper gastrointestinal disease. Intern Med. 50(7):713-7. 2011 |
| 29 | Kabir SM, Kikuchi K, Asakura M, Shiramaru S, Tsuruoka N, Goto A, Hinenoya A, Yamasaki S. Evaluation of a cytolethal distending toxin (cdt) gene-based species-specific multiplex PCR assay for the identification of Campylobacter strains isolated from diarrheal patients in Japan. Jpn J Infect Dis. 2011;64(1):19-27. 2011 |
| 30 | Kaga M, Sugita T, Nishikawa A, Wada Y, Hiruma M, Ikeda S. Molecular analysis of the cutaneous Malassezia microbiota from the skin of patients with atopic dermatitis of different severities. Mycoses. Jul;54(4):e24-8. 2011 |
| 31 | Kawasaki J, Ushio H, Kinoshita H, Fukai T, Niyonsaba F, Takai T, Ogawa H, Okumura K, Ikeda S. Viral infection induces Thymic stromal lymphopoietin (TSLP) in human keratinocytes. J Dermatol Sci. May;62(2):131-4. 2011 |
| 32 | Kina K, Masuda H, Nakayama H, Nagatsuka Y, Nabetani T, Hirabayashi Y, Takahashi Y, Shimada K, Daida H, Ogawa H, Takamori K, Iwabuchi K. The novel neutrophil differentiation marker phosphatidylglucoside mediates neutrophil apoptosis. J Immunol. May 1;186(9):5323-32. 2011 |
| 33 | Kiyanagi T, Iwabuchi K, Shimada K, Hirose K, Miyazaki T, Sumiyoshi K, Iwahara C, Nakayama H, Masuda H, Mokuno H, Sato S, Daida H. Involvement of cholesterol-enriched microdomains in class A scavenger receptor-mediated responses in human macrophages. Atherosclerosis. Mar;215(1):60-9. 2011 |
| 34 | Kodani T, Osada T, Terai T, Ohkusa T, Shibuya T, Sakamoto N, Beppu K, Kato J, Nagahara A, Watanabe H, Watanabe S. Successful endoscopic mucosal resection of a solitary extramedullary plasmacytoma in the sigmoid colon. Endoscopy. 43 Suppl 2 UCTN:E298-9. 2011 |
| 35 | Koga H, Miyano G, Takahashi T, Shimotakahara A, Kato Y, Lane GJ, Okazaki T, Yamataka A. Laparoscopic portoenterostomy for uncorrectable biliary atresia using Kasai's original technique. J Laparoendosc Adv Surg Tech A. Apr;21(3):291-4. 2011 |
| 36 | Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K, Yagita H. Importin beta1 Protein-mediated Nuclear Localization of Death Receptor 5 (DR5) Limits DR5/Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Cell Death of Human Tumor Cells. J Biol Chem. Dec 16;286(50):43383-93. 2011 |
| 37 | Le TA, Takai T, Vu AT, Kinoshita H, Chen X, Ikeda S, Ogawa H, Okumura K. Flagellin induces the expression of thymic stromal lymphopoietin in human keratinocytes via toll-like receptor 5. Int Arch Allergy Immunol. Apr;155(1):31-7. 2011 |
| 38 | Li S, Skov RL, Han X, Larsen AR, Larsen J, Sørum M, Wulf M, Voss A, Hiramatsu K, Ito T. Novel types of staphylococcal cassette chromosome mec elements identified in CC398 methicillin resistant Staphylococcus aureus strains. Antimicrob Agents Chemother. Jun;55(6):3046-50. 2011 |
| 39 | Liao CW, Sukati H, Nara T, Tsubouchi A, Chou CM, Jian JY, Huang YC, Chang WS, Chiu WT, Huang YH, Fan CK. Prevalence of Schistosoma haematobium Infection among Schoolchildren in Remote Areas Devoid of Sanitation in Northwestern Swaziland, Southern Africa. Jpn J Infect Dis. 64:322-326. 2011 |
| 40 | Ma J, Usui Y, Takeda K, Harada N, Yagita H, Okumura K, Akiba H. TIM-1 signaling in B cells regulates antibody production. Biochem Biophys Res Commun. Mar 11;406(2):223-8. 2011 |
| 41 | Makiuchi T, Annoura T, Hashimoto M, Hashimoto T, Aoki T, Nara T. Compartmentalization of a glycolytic enzyme in Diplonema, a non-kinetoplastid Euglenozoan. Protist. 162(3):482-489. 2011 |
| 42 | Matsumoto K, Nagahara A, Sakamoto N, Suyama M, Konuma H, Morimoto T, Sagawa E, Ueyama H, Takahashi T, Beppu K, Shibuya T, Osada T, Yoshizawa T, Ogihara T, Watanabe S. A new traction device for facilitating endoscopic submucosal dissection (ESD) for early gastric cancer: the "medical ring". Endoscopy. 43 Suppl 2:E67-8. 2011 |
| 43 | Matsumoto K, Nagahara A, Terai T, Ueyama H, Ritsuno H, Mori H, Nakae K, Beppu K, Shibuya T, Sakamoto N, Osada T, Ogihara T, Yao T, Watanabe S. Evaluation of new subclassification of type V(I) pit pattern for determining the depth and type of invasion of colorectal neoplasm. J Gastroentor 46,1,31-38. 2011 |
| 44 | Matsumoto T, Shimizu T, Aoshima Y, Oda H, Kikuchi K, Katsura H, Fujiwara T, Onuki T. Endobronchial hamartoma with obstructive pneumonia due to Nocardia asiatica. Gen Thorac Cardiovasc Surg. Feb;59(2):141-4. 2011 |
| 45 | Matsuo M, Hishinuma T, Katayama Y, Cui L, Kapi M, Hiramatsu K. Mutation of RNA Polymerase {beta} Subunit (rpoB) Promotes hVISA-to-VISA Phenotypic Conversion of Strain Mu3. Antimicrob Agents Chemother. Sep;55(9):4188-95. 2011 |
| 46 | Miyahara K, Kato Y, Koga H, Dizon R, Lane GJ, Suzuki R, Akazawa C, Yamataka A. Visualization of enteric neural crest cell migration in SOX10 transgenic mouse gut using time-lapse fluorescence imaging. J Pediatr Surg. Dec;46(12):2305-8. 2011 |
| 47 | Miyano G, Hayashi T, Arakawa A, Nawata M, Takasaki Y, Tanaka N, Lane GJ, Kato Y, Yamataka A, Okazaki T. Choledochal cyst and systemic lupus erythematosus. Pediatr Surg Int. Jan;27(1):111-3. 2011 |
| 48 | Miyano G, Koga H, Shimotakahara A, Takahashi T, Kato Y, Lane GJ, Okazaki T, Yamataka A. Intralaparoscopic endoscopy: its value during laparoscopic repair of choledochal cyst. Pediatr Surg Int. May;27(5):463-6. 2011 |
| 49 | Miyano G, Miyahara K, Halibieke A, Lane GJ, Okazaki T, Yamataka A. Intraabdominal laparoscopy-assisted "open" vessel ligation of testicular vessels: a potential treatment for varicocele. J Laparoendosc Adv Surg Tech A. Oct;21(8):749-51. 2011 |
| 50 | Miyano G, Urao M, Lane GJ, Kato Y, Okazaki T, Yamataka A. A prospective analysis of endoloops and endostaples for closing the stump of the appendix in children. J Laparoendosc Adv Surg Tech A. Mar;21(2):177-9. 2011 |
| 51 | Miyano G, Urao M, Lane GJ, Kato Y, Okazaki T, Yamataka A. Appendiceal stump closure in children with complicated appendicitis: A prospective analysis of endoloops versus endostaples. Asian J Endosc Surg 4. 116–119. 2011 |
| 52 | Mori H, Sakamoto N, Osada T, Ritsuno H, Hidaka Y, Nakae K, Matsumoto K, Beppu K, Shibuya T, Yoshizawa T, Nagahara A, Otaka M, Ogihara T, Arai F, Watanabe S. The 'Loop Clip' is useful for closing large mucosal defects after colorectal endoscopic submucosal dissection: a preliminary clinical study. Dig Endosc. Oct;23(4):330-1. 2011 |
| 53 | Murakami T, Suzuki K, Tamura H, Nagaoka I. Suppressive actions of resolvin D1 on the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. Exp Ther Med Jan - Feb. 2: 57-61 2011 |
| 54 | Nagaoka I, Igarashi M, Hua J, Yomogida S, Sakamoto K. Recent aspects of the anti-inflammatory actions of glucosamine. Carbohydrate Polymers Mar 84: 825-830. 2011 |
| 55 | Nakajima K, Nagahara A, Kurosawa A, Seyama K, Asaoka D, Osada T, Hojo M, Watanabe S. Quit smoking improves gastroesophageal reflux symptoms and quality of life. Health 3(11)677-83. 2011 |
| 56 | Nakano H, Ushio H. An unexpected role for autophagy in degranulation of mast cells. Autophagy. Jun;7(6):657-9. 2011 |
| 57 | Ng W, Ikeda S. Standardized, defined serum-free culture of a human skin equivalent on fibroblast-populated collagen scaffold. Acta Derm Venereol. Jun;91(4):387-91. 2011 |
| 58 | Ng W, Ikeda S. Use of sun-protective items by Japanese pedestrians: a cross-sectional observational study. Arch Dermatol. Oct;147(10):1167-70. 2011 |
| 59 | Ogawa T, Kasahara K, Yonekawa S, Nakagawa C, Maeda K, Konishi M, Mikasa K, Kikuchi K. Nocardia beijingensis pulmonary infection successfully treated with intravenous beta-lactam antibiotics and oral minocycline. J Infect Chemother. Oct;17(5):706-9. 2011 |
| 60 | Oguro M, Koike M, Ueno T, Asaoka D, Mori H, Nagahara A, Uchiyama Y, Watanabe S. Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease. J Gastroenterol. May;46(5):629-38. 2011 |
| 61 | Ohashi R, Kato M, Katsura Y, Takekawa H, Hoshika Y, Sugawara T, Yoshimi K, Togo S, Nagaoka T, Seyama K, Takahashi K, Tsuchiya K, Misawa S, Kikuchi K. Breakthrough lung Scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance (MGUS). Med Mycol J. Mar 52(1):33-8. 2011 |
| 62 | Ohtsuka Y, Okada K, Yamakawa Y, Ikuse T, Baba Y, Inage E, Fujii T, Izumi H, Oshida K, Nagata S, Yamashiro Y, Shimizu T. ω-3 fatty acids attenuate mucosal inflammation in premature rat pups. J Pediatr Surg. Mar;46(3):489-95. 2011 |
| 63 | Okazaki T, Nakazawa N, Ogasawara Y, Shoji H, Shimizu T, Makino S, Takeda S, Lane GJ, Yamataka A. Increase in fetal pulmonary artery diameters during late gestation is a predictor of outcome in congenital diaphragmatic hernia with liver herniation. J Pediatr Surg. Dec;46(12):2254-9. 2011 |
| 64 | Okazaki T, Nishimura K, Takahashi T, Shoji H, Shimizu T, Tanaka T, Takeda S, Inada E, Lane GJ, Yamataka A. Indications for thoracoscopic repair of congenital diaphragmatic hernia in neonates. Pediatr Surg Int. Jan;27(1):35-8. 2011 |
| 65 | Osada T, Arakawa A, Sakamoto N, Ueyama H, Shibuya T, Ogihara T, Yao T, Watanabe S. Autofluorescence imaging endoscopy for identification and assessment of inflammatory ulcerative colitis. World J Gastroenterol. Dec 14;17(46):5110-6. 2011 |
| 66 | Penaloza-MacMaster P, Ur Rasheed A, Iyer SS, Yagita H, Blazar BR, Ahmed R. Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice. J Virol. Jul;85(13):6168-74. 2011 |
| 67 | Piao JH, Hasegawa M, Heissig B, Hattori K, Takeda K, Iwakura Y, Okumura K, Inohara N, Nakano H. Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease. J Biol Chem. May 20;286(20):17879-88. 2011 |
| 68 | Ritsuno H, Sakamoto N, Mitomi H, Namihisa A, Mori H, Nakae K, Matsumoto K, Beppu K, Shibuya T, Osada T, Nagahara A, Otaka M, Terai T, Ogihara T, Yao T, Watanabe S. Advanced colorectal cancer with double-hump camel-like appearance. Dig Endosc. Oct;23(4):329. 2011 |
| 69 | Salek-Ardakani S, Flynn R, Arens R, Yagita H, Smith GL, Borst J, Schoenberger SP, Croft M. The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice. J Clin Invest. Jan 4;121(1):296-307. 2011 |
| 70 | Sato-Hayashizaki A, Ohtsuji M, Lin Q, Hou R, Ohtsuji N, Nishikawa K, Tsurui H, Sudo K, Ono M, Izui S, Shirai T, Takai T, Nishimura H, Hirose S. Presumptive role of 129 strain-derived Sle16 loeus for rheumatoid arthritis in a new mouse model with FcγRIIB-deficient C57BL/6 genetic backgraound Arthritis Rheum. Oct;63(10):2930-8. 2011 |
| 71 | Shibuya T, Ohkusa T, Yokoyama T, Matsumoto K, Beppu K, Sakamoto N, Osada T, Nagahara A, Otaka M, Ogihara T, Watanabe S. Colonic mucosal lesions associated with low-dose aspirin: a case control study. Scand J Gastroenterol 46,810-817. 2011 |
| 72 | Shimotakahara A, Nakazawa N, Wada A, Nagata S, Koga H, Takahashi T, Miyano G, Lane GJ, Yamataka A. Tubularized incised plate urethroplasty with dorsal inlay graft prevents meatal/neourethral stenosis: a single surgeon's experience. J Pediatr Surg. Dec;46(12):2370-2. 2011 |
| 73 | Shoji H, Hisata K, Suzuki M, Yoshikawa N, Suganuma H, Ohkawa N, Shimizu T. Effects of parenteral soybean oil lipid emulsion on the long-chain polyunsaturated fatty acid profile in very-low-birth-weight infants. Acta Paediatr. Jul;100(7):972-6. 2011 |
| 74 | Shoji M, Cui L, Iizuka R, Komoto A, Neoh HM, Watanabe Y, Hishinuma T, Hiramatsu K. WalK and ClpP Mutations Confer Decreased Susceptibility to Vancomycin in Staphylococcus aureus. Antimicrob Agents Chemother. Aug;55(8):3870-81. 2011 |
| 75 | Shukuya R, Hasegawa T, Niwa Y, Okuma K, Ikeda S. Granulocyte and monocyte adsorption apheresis for generalized pustular psoriasis. J Dermatol. Dec;38(12):1130-4. 2011 |
| 76 | Sugasawa Y, Yamaguchi K, Kumakura S, Murakami T, Kugimiya T, Suzuki K, Nagaoka I, Inada E. The effect of one-lung ventilation upon pulmonary inflammatory responses during lung resection. J Anesth. Apr;25(2):170-7. 2011 |
| 77 | Sugiyama R, Hayafune M, Habu Y, Yamamoto N, Takaku H. HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses. Nucleic Acids Res. Jan;39(2):589-98. 2011 |
| 78 | Suzuki K, Murakami T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I. Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells. Int Immunol. Mar;23(3):185-93. 2011 |
| 79 | Suzuki K, Nagaoka I. Effect of antimicrobial cathelicidin peptides on the endothelial cell apoptosis. Inflamm Regener 31(4):375-381. 2011 |
| 80 | Tajima K, Miura K, Ishiwata T, Takahashi F, Yoshioka M, Minakata K, Murakami A, Sasaki S, Iwakami S, Annoura T, Hashimoto M, Nara T, Takahashi K. Sex hormones alter Th1 responses and enhance granuloma formation in the lung. Respiration. 81(6):491-498. 2011 |
| 81 | Takahashi T, Koga H, Tanaka T, Shoji H, Takeda S, Shimizu T, Lane GJ, Yamataka A, Okazaki T. Pulmonary artery size has prognostic value in low birth weight infants with congenital diaphragmatic hernia. Pediatr Surg Int. Aug;27(8):847-50. 2011 |
| 82 | Takai T, Ikeda S. Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases. Allergol Int. 2011 Mar;60(1):25-35. 2011 |
| 83 | Tamaki K, Otaka M, Takada M, Yamamoto S, Odashima M, Itoh H, Watanabe S. Evidence for enhanced cytoprotective function of HSP90-overexpressing small intestinal epithelial cells. Dig Dis Sci. Jul;56(7):1954-61. 2011 |
| 84 | Taniguchi G, Nagahara A, Matsumoto K, Ritsuno H, Igusa Y, Sasaki H, Beppu K, Shibuya T, Sakamoto N, Osada T, Kawabe M, Terai T, Ogihara T, Watanabe S. Asymptomatic anisakiasis of the colon incidentally found by colonoscopy. Clin J Gastroenterol 4(6):371-73. 2011 |
| 85 | Tokunaga F, Nakagawa T, Nakahara M, Saeki Y, Taniguchi M, Sakata S, Tanaka K, Nakano H, Iwai K.S HARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex. Nature. Mar 31;471(7340):633-6. 2011 |
| 86 | Ushio H, Ueno T, Kojima Y, Komatsu M, Tanaka S, Yamamoto A, Ichimura Y, Ezaki J, Nishida K, Komazawa-Sakon S, Niyonsaba F, Ishii T, Yanagawa T, Kominami E, Ogawa H, Okumura K, Nakano H. Crucial role for autophagy in degranulation of mast cells. J Allergy Clin Immunol. May;127(5):1267-76.e6. 2011 |
| 87 | Vu AT, Chen X, Xie Y, Kamijo S, Ushio H, Kawasaki J, Hara M, Ikeda S, Okumura K, Ogawa H, Takai T. Extracellular Double-Stranded RNA Induces TSLP via an Endosomal Acidification-and NF-kB-Dependent Pathway in Human Keratinocytes. J Invest Dermatol. Nov;131(11):2205-12. 2011 |
| 88 | Wang X, Ikejima K, Kon K, Arai K, Aoyama T, Okumura K, Abe W, Sato N, Watanabe S. Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells. J Hepatol. Aug;55(2):379-87. 2011 |
| 89 | Watanabe S, Enomoto N, Koike K, Izumi N, Takikawa H, Hashimoto E, Moriyasu F, Kumada H, Imawari M. PERFECT Study Group.Cancer preventive effect of pegylated interferon α-2b plus ribavirin in a real-life clinical setting in Japan: PERFECT interim analysis. Hepatol Res. Oct;41(10):955-64. 2011 |
| 90 | Watanabe Y, Cui L, Katayama Y, Kishii K, Hiramatsu K. Impact of RpoB Mutations on Decreased Susceptibility to Vancomycin in Staphylococcus aureus. J Clin Microbiol. Jul;49(7):2680-4. 2011 |
| 91 | Watanabe Y, Naito T, Kikuchi K, Amari Y, Uehara Y, Isonuma H, Hisaoka T, Yoshida T, Yaginuma K, Takaya N, Daida H, Hiramatsu K. Infective endocarditis with Lactococcus garvieae in Japan: a case report. J Med Case Reports. Aug 9;5(1):356. 2011 |
| 92 | Yamaguchi K, Sugasawa Y, Takeuchi K, Kugimiya T, Kumakura S, Iwanuma Y, Kajiyama Y, Tsurumaru M, Nagaoka I, Inada E. Effects of sivelestat on bronchial inflammatory responses after esophagectomy. Int J Mol Med. Aug;28(2):187-92. 2011 |
| 93 | Yamazaki S, Okada K, Maruyama A, Matsumoto M, Yagita H, Seya T. TLR2-dependent induction of IL-10 and Foxp3+CD25+CD4+ regulatory T cells prevents effective anti-tumor immunity induced by Pam2 lipopeptides in vivo. PLoS One Apr 20;6(4):e18833. 2011 |
| 94 | Yanagisawa N, Haruta I, Kikuchi K, Shibata N, Yagi J. Are Dysregulated Inflammatory Responses to Commensal Bacteria Involved in the Pathogenesis of Hepatobiliary-Pancreatic Autoimmune Disease? An Analysis Using Mice Models of Primary Biliary Cirrhosis and Autoimmune Pancreatitis. ISRN Gastroenterol. 2011:513514. 2011 |
| 95 | Yasuma A, Ochiai T, Azuma M, Nishiyama H, Kikuchi K, Kondo M, Handa H. Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions. J Med Microbiol. Jul;60(Pt 7):1038-42. 2011 |
| 96 | Zhang M, Ito T, Li S, Jin J, Takeuchi F, Lauderdale TL, Higashide M, Hiramatsu K. Identification of the third type of PVL phage in ST59 methicillin-resistant Staphylococcus aureus (MRSA) strains. FEMS Microbiol Lett. Oct;323(1):20-8. 2011 |
| 97 | Zhang M, O'Donoghue MM, Ito T, Hiramatsu K, Boost MV. Prevalence of antiseptic-resistance genes in Staphylococcus aureus and coagulase-negative staphylococci colonising nurses and the general population in Hong Kong. J Hosp Infect. Jun;78(2):113-7. 2011 |
英文原著（2010年）
| 1 | Ando K, Hasegawa K, Shindo K, Furusawa T, Fujino T, Kikugawa K, Nakano H, Takeuchi O, Akira S, Akiyama T, Gohda J, Inoue J, Hayakawa M. Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling. FEBS J. May;277(9):2051-66. 2010 |
| 2 | Ando S, Amano H, Amano E, Minowa K, Watanabe T, Nakano S, Nakiri Y, Morimoto S, Tokano Y, Lin Q, Hou R, Ohtsuji M, Tsurui H, Hirose S, Takasaki Y. FTY720 exerts a survival advantage through the prevention of end-stage glomerular inflammation in lupus-prone BXSB mice. Biochem Biophys Res Commun. Apr 9;394(3):804-10. 2010 |
| 3 | Beppu K, Nagahara A, Terai T, Matsumoto K, Shibuya T, Sakamoto N, Osada T, Kawabe M, Otaka M, Ogihara T, Watanabe S. Clinicopathological characteristics of colorectal cancer less than 10 mm in diameter and invading submucosa and below. J Gastroenterol Hepatol. May;25 Suppl 1:S57-61. 2010 |
| 4 | Chiba Y, Shida K, Nagata S, Wada M, Bian L, Wang C, Shimizu T, Yamashiro Y, Kiyoshima-Shibata J, Nanno M, Nomoto K. Well-controlled proinflammatory cytokine responses of Peyer's patch cells to probiotic Lactobacillus casei. Immunology. Jul;130(3):352-62. 2010 |
| 5 | Cui L, Isii T, Fukuda M, Ochiai T, Neoh HM, Camargo IL, Watanabe Y, Shoji M, Hishinuma T, Hiramatsu K. An RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus. Antimicrob Agents Chemother. Dec;54(12):5222-33. 2010 |
| 6 | Dias P, Giannoni F, Lee LN, Han D, Yoon S, Yagita H, Azuma M, Sarawar SR. CD4 T-cell help programs a change in CD8 T-cell function enabling effective long-term control of murine gammaherpesvirus 68: role of PD-1-PD-L1 interactions. J Virol. Aug;84(16):8241-9. 2010 |
| 7 | Fujimori M, Hisata K, Nagata S, Matsunaga N, Komatsu M, Shoji H, Sato H, Yamashiro Y, Asahara T, Nomoto K, Shimizu T. Efficacy of bacterial ribosomal RNA-targeted reverse transcription-quantitative PCR for detecting neonatal sepsis: a case control study. BMC Pediatr. Jul 29;10:53. 2010 |
| 8 | Fujimura J, Takeda K, Kaduka Y, Saito M, Akiba H, Yagita H, Yamashiro Y, Shimizu T, Okumura K. Contribution of B7RP-1/ICOS co-stimulation to lethal acute GVHD. Pediatr Transplant. Jun;14(4):540-8. 2010 |
| 9 | Fukuo Y, Shibuya T, Fukumura Y, Mizui T, Sai JK, Nagahara A, Tsukada A, Matsumoto T, Suyama M, Watanabe S. Reactive lymphoid hyperplasia of the liver associated with primary biliary cirrhosis. Med Sci Monit. Jul;16(7):CS81-6. 2010 |
| 10 | Furukawa T, Kishiro M, Fukunaga H, Ohtsuki M, Takahashi K, Akimoto K, Shimizu T, Kawasaki S, Kumasaka T. Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo. Pediatr Cardiol. Aug;31(6):773-9. 2010 |
| 11 | Haruna K, Suga Y, Oizumi A, Mizuno Y, Endo H, Shimizu T, Hasegawa T, Ikeda S. Severe form of keratitis-ichthyosis-deafness (KID) syndrome associated with septic complications. J Dermatol. Jul;37(7):680-2. 2010 |
| 12 | Haruta I, Kikuchi K, Hashimoto E, Nakamura M, Miyakawa H, Hirota K, Shibata N, Kato H, Arimura Y, Kato Y, Uchiyama T, Nagamune H, Kobayashi M, Miyake Y, Shiratori K, Yagi J. Long-term bacterial exposure can trigger nonsuppurative destructive cholangitis associated with multifocal epithelial inflammation. Lab Invest. Apr;90(4):577-88. 2010 |
| 13 | Hasegawa T, Suga Y, Mizuno Y, Haruna K, Ogawa H, Ikeda S. Efficacy of photodynamic therapy with topical 5-aminolevulinic acid using intense pulsed light for Bowen's disease. J Dermatol. Jul;37(7):623-8. 2010 |
| 14 | Hasegawa T，Matsukura T， Ikeda S. Mesotherapy for benign symmetrical lipomatosis. Aesthetic Plast Surg，Apr；34(2):153-156 2010 |
| 15 | Higashiyama M, Ito T, Han X, Ono K, Minamimura K, Sakakibara F, Tanno A, Nishiyama J, Hatada J, Hiramatsu K, Kawana A. Epidural abscess caused by community-associated methicillin-resistant Staphylococcus aureus strain USA300 in Japan. J Infect Chemother. Oct;16(5):345-9. 2010 |
| 16 | Inami K, Abe M, Takeda K, Hagiwara Y, Maeda M, Segawa T, Suyama M, Watanabe S, Hino O. Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo. Cancer Sci. Apr;101(4):969-74. 2010 |
| 17 | Iwabuchi K, Nakayama H, Iwahara C, Takamori K. Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction. FEBS Lett. May 3;584(9):1642-52. 2010 |
| 18 | Kaneko N, Hisata K, Shoji H, Tanaka K, Nakazawa T, Shimizu T. Effects of early enteral feeding on fecal elastase 1 and plasma secretin. Pediatr Int. Aug;52(4):607-10. 2010 |
| 19 | Kato J, Nagahara A, Iijima K, Kodani T, Higashihara Y, Yoshimura M, Serizawa N, Osada T, Yoshizawa T, Otaka M, Watanabe S. Phase I study of paclitaxel, cisplatin and 5-fluorouracil combination chemotherapy for unresectable / recurrent gastric cancer. Adv Med Sci. Dec 30;55(2):137-42. 2010 |
| 20 | Koga H, Miyano G, Takahashi T, Shimotakahara A, Kato Y, Lane GJ, Okazaki T, Yamataka A. Comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus. J Pediatr Surg. Dec;45(12):2394-7. 2010 |
| 21 | Koga H, Okazaki T, Kato Y, Lane GJ, Yamataka A. Anal canal duplication: experience at a single institution and literature review. Pediatr Surg Int. Oct;26(10):985-8. 2010 |
| 22 | Kohama H, Harakuni T, Kikuchi M, Nara T, Takemura Y, Miyata T, Sato Y, Hirayama K, Arakawa T. Intranasal administration of Schistosoma japonicum paramyosin induced robust long-lasting systemic and local antibody as well as delayed-type hypersensitivity responses, but failed to confer protection in a mouse infection model. Jpn J Infect Dis. May;63(3):166-72. 2010 |
| 23 | Komiyama M, Fu K, Morimoto T, Konuma H, Yamagata T, Izumi Y, Miyazaki A, Watanabe S. A novel endoscopic ablation of gastric antral vascular ectasia. World J Gastrointest Endosc. Aug 16;2(8):298-300. 2010 |
| 24 | Kon K, Ikejima K, Okumura K, Arai K, Aoyama T, Watanabe S. Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen. Am J Physiol Gastrointest Liver Physiol. Aug;299(2):G329-37. 2010 |
| 25 | Kon K, Kim JS, Uchiyama A, Jaeschke H, Lemasters JJ. Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes. Toxicol Sci. Sep;117(1):101-8. 2010 |
| 26 | Kudo T, Aoyagi Y, Fujii T, Ohtsuka Y, Nagata S, Shimizu T. Development of Candida albicans colitis in a child undergoing steroid therapy for ulcerative colitis. J Pediatr Gastroenterol Nutr. Jul;51(1):96-9. 2010 |
| 27 | Le TA, Takai T, Vu AT, Kinoshita H, Ikeda S, Ogawa H, Okumura K. Glucocorticoids inhibit double-stranded RNA-induced thymic stromal lymphopoietin release from keratinocytes in an atopic cytokine milieu more effectively than tacrolimus. Int Arch Allergy Immunol. 153(1):27-34. 2010 |
| 28 | Lin Q, Hou R, Sato A, Ohtsuji M, Ohtsuji N, Nishikawa K, Tsurui H, Amano H, Amano E, Sudo K, Nishimura H, Shirai T, Hirose S. Inhibitory IgG Fc receptor promoter region polymorphism is a key genetic element for murine systemic lupus erythematosus. J Autoimmun. Jun;34(4):356-63. 2010 |
| 29 | Lkhagvadorj E, Nagata S, Wada M, Bian L, Wang C, Chiba Y, Yamashiro Y, Shimizu T, Asahara T, Nomoto K. Anti-infectious activity of synbiotics in a novel mouse model of methicillin-resistant Staphylococcus aureus infection. Microbiol Immunol. May;54(5):265-75. 2010 |
| 30 | Missiou A, Rudolf P, Stachon P, Wolf D, Varo N, Aichele P, Colberg C, Hoppe N, Ernst S, Münkel C, Walter C, Sommer B, Hilgendorf I, Nakano H, Bode C, Zirlik A. TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation. Circ Res. Sep 17;107(6):757-66. 2010 |
| 31 | Miyahara K, Kato Y, Koga H, Lane GJ, Inoue T, Akazawa C, Yamataka A. Abnormal enteric innervation identified without histopathologic staining in aganglionic colorectum from a mouse model of Hirschsprung's disease. J Pediatr Surg. Dec;45(12):2403-7. 2010 |
| 32 | Miyano G, Okazaki T, Kato Y, Marusasa T, Takahashi T, Lane GJ, Yamataka A. Open versus laparoscopic treatment for pan-peritonitis secondary to perforated appendicitis in children: a prospective analysis. J Laparoendosc Adv Surg Tech A. Sep;20(7):655-7. 2010 |
| 33 | Mori H, Shibuya T, Osada T, Kodani T, Higashihara Y, Serizawa N, Kato J, Nagahara A, Ogihara T, Watanabe S. Response to chemotherapy in a case of gastric adenocarcinoma producing granulocyte colony-stimulating factor. Med Sci Monit. 2010 Oct;16(10):CS119-23. 2010 |
| 34 | Morimoto T, Fu KI, Konuma H, Izumi Y, Asano A, Kokubu S, Miyazaki A, Watanabe S. Endoscopic hemostasis with hemoclips for active gastric variceal bleeding. Endoscopy. 42 Suppl 2:E333-4. 2010 |
| 35 | Morimoto T, Fu KI, Konuma H, Izumi Y, Matsuyama S, Ogura K, Miyazaki A, Watanabe S. Peeling a giant ileal lipoma with endoscopic unroofing and submucosal dissection. World J Gastroenterol. Apr 7;16(13):1676-9. 2010 |
| 36 | Nagahara A, Asaoka D, Hojo M, Oguro M, Shimada Y, Ishikawa D, Osada T, Kawabe M, Yoshizawa T, Otaka M, Watanabe S. Observational comparative trial of the efficacy of proton pump inhibitors versus histamine-2 receptor antagonists for uninvestigated dyspepsia. J Gastroenterol Hepatol. May;25 Suppl 1:S122-8. 2010 |
| 37 | Nagahara A, Hojo M, Asaoka D, Watanabe S. Maintenance therapy of gastroesophageal reflux disease. Clin J Gastroenterol April;3(2)61-68 2010 |
| 38 | Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M. Evaluation of the effect of α-defensin human neutrophil peptides on neutrophil apoptosis. Int J Mol Med. Dec;26(6):925-34. 2010 |
| 39 | Nakagawa C, Kasahara K, Yonekawa S, Ogawa T, Kutsuna S, Maeda K, Konishi M, Kikuchi K, Mikasa K. Purulent pericarditis due to Streptococcus pneumoniae diagnosed by pneumococcal urinary antigen assay and 16S rDNA sequence of the pericardial fluid. Intern Med. 2010;49(15):1653-6. 2010 |
| 40 | Niwa Y, Potaczek DP, Kanada S, Takagi A, Shimokawa N, Ito T, Mitsuishi K, Okubo Y, Tajima M, Hobo A, Ng W, Tsuboi R, Ikeda S, Ogawa H, Okumura K, Nishiyama C. FcepsilonRIalpha gene (FCER1A) promoter polymorphisms and total serum IgE levels in Japanese atopic dermatitis patients. Int J Immunogenet. Apr;37(2):139-41. 2010 |
| 41 | Niyonsaba F, Ushio H, Hara M, Yokoi H, Tominaga M, Takamori K, Kajiwara N, Saito H, Nagaoka I, Ogawa H, Okumura K. Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol. Apr 1;184(7):3526-34. 2010 |
| 42 | Obinata K, Okumura A, Nakazawa T, Kamata A, Niizuma T, Kinoshita K, Shimizu T. Norovirus encephalopathy in a previously healthy child. Pediatr Infect Dis J. Nov;29(11):1057-9. 2010 |
| 43 | Ohata R, Okazaki T, Ishizaki Y, Fujimura J, Shimizu T, Lane GJ, Yamataka A, Kawasaki S. Pancreaticoduodenectomy for pancreatoblastoma: a case report and literature review. Pediatr Surg Int. Apr;26(4):447-50. 2010 |
| 44 | Ohji G, Kikuchi K, Inoue K, Imoto K, Yamamoto S, Hosokawa N, Kamei K, Iwata K. Progressive disseminated histoplasmosis in an immunocompetent patient as an underrecognized imported mycosis in Japan. J Infect Chemother. Dec;16(6):443-5. 2010 |
| 45 | Ohtani K, Ohtsuka Y, Ikuse T, Baba Y, Yamakawa Y, Aoyagi Y, Fujii T, Kudo T, Nagata S, Shimizu T. Increased mucosal expression of GATA-3 and STAT-4 in pediatric ulcerative colitis. Pediatr Int. Aug;52(4):584-9. 2010 |
| 46 | Ohtsuki A, Hasegawa T, Ikeda S. Treatment of alopecia areata with 308-nm excimer lamp. J Dermatol. Dec;37(12):1032-5. 2010 |
| 47 | Okazaki T, Ohata R, Miyano G, Lane GJ, Takahashi T, Yamataka A. Laparoscopic splenopexy and gastropexy for wandering spleen associated with gastric volvulus. Pediatr Surg Int. Oct;26(10):1053-5. 2010 |
| 48 | Okubo H, Kokubu S, Komiyama M, Yamagata H, Uchiyama A, Miyazaki A, Watanabe S. Radiofrequency ablation of hepatocellular carcinoma: The feasibility of magnetic resonance imaging with gadolinium ethoxybenzyl diethylene triamine pentaacetic acid for evaluating the ablative margin. Hepatology Research 40(10):1034-41 2010 |
| 49 | Sai JK, Suyama M, Kubokawa Y, Matsumura Y, Inami K, Watanabe S, Kirino E. Identification of cerebral response to balloon distention of the bile duct. World J Gastroenterol. Apr 14;16(14):1772-5. 2010 |
| 50 | Saito Y, Uraoka T, Yamaguchi Y, Hotta K, Sakamoto N, Ikematsu H, Fukuzawa M, Kobayashi N, Nasu J, Michida T, Yoshida S, Ikehara H, Otake Y, Nakajima T, Matsuda T, Saito D. A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video). Gastrointest Endosc. Dec;72(6):1217-25. 2010 |
| 51 | Sakaguchi S, Saito M, Tsuji H, Asahara T, Takata O, Fujimura J, Nagata S, Nomoto K, Shimizu T. Bacterial rRNA-targeted reverse transcription-PCR used to identify pathogens responsible for fever with neutropenia. J Clin Microbiol. 2010 May;48(5):1624-8. |
| 52 | Shibuya T, Ohkusa T, Yokoyama T, Harada A, Beppu K, Sakamoto N, Osada T, Nagahara A, Terai T, Otaka M, Ogihara T, Watanabe S. Colonic mucosal lesions associated with long-term or short-term administration of nonsteroidal anti-inflammatory drugs. Colorectal Dis. Nov;12(11):1113-21. 2010 |
| 53 | Shibuya T, Osada T, Mitomi H, Takeda T, Nomura O, Nakayama H, Hidaka Y, Mori H, Beppu K, Sakamoto N, Nagahara A, Otaka M, Ogihara T, Yao T, Watanabe S. Jejunal capillary hemangioma treated by using double-balloon endoscopy (with video) . Gastrointest Endosc. Sep;72(3):660-1. 2010 |
| 54 | Shimotakahara A, Sueyoshi R, Lane GJ, Okazaki T, Nishimura K, Inada E, Yamataka A. The benefit of stay sutures during thoracoscopic esophagoesophagostomy in patients with esophageal atresia: a technical report. Pediatr Surg Int. Apr;26(4):443-6. 2010 |
| 55 | Shimura E, Hozumi N, Kanagawa O, Metzger D, Chambon P, Radtke F, Hirose S, Nakano N. Epidermal gammadelta T cells sense precancerous cellular dysregulation and initiate immune responses. Int Immunol. Apr;22(4):329-40. 2010 |
| 56 | Shono T, Kato M, Aoyagi Y, Haruna H, Fujii T, Kudo T, Ohtsuka Y, Shimizu T. Assessment of Growth Disturbance in Japanese Children with IBD. Int J Pediatr. 2010:958915. 2010 |
| 57 | Someya A, Moss J, Nagaoka I. The guanine nucleotide exchange protein for ADP-ribosylation factor 6, ARF-GEP100/BRAG2, regulates phagocytosis of monocytic phagocytes in an ARF6-dependent process. J Biol Chem. Oct 1;285(40):30698-707. 2010 |
| 58 | Suganuma H, Arai Y, Kitamura Y, Hayashi M, Okumura A, Shimizu T. Maternal docosahexaenoic acid-enriched diet prevents neonatal brain injury. Neuropathology. Dec;30(6):597-605. 2010 |
| 59 | Sugihara E, Naito T, Aiba M, Matsuda N, Shiga T, Amari Y, Haba Y, Mitsuhashi K, Isonuma H, Dambara T. A case of synovitis acne pustulosis hyperostosis osteitis (SAPHO) syndrome. General Medicine Dec 11(2) 91-92 2010 |
| 60 | Sugimura R,，Mayuzumi N， Ikeda S. Effects of Cyclooxygenase－1 or －2 inhibitors on expressions of ATP2A2 and ATP2C1 in cultured normal human keratinocytes. 順天堂医学 56(6) 550-7 2010 |
| 61 | Tajima K, Ohashi R, Sekido Y, Hida T, Nara T, Hashimoto M, Iwakami S, Minakata K, Yae T, Takahashi F, Saya H, Takahashi K. Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells. Oncogene. Apr 1;29(13):1941-51. 2010 |
| 62 | Takahashi T, Otaka M, Odashima M, Tamaki K, Takada M, Izumi Y, Shibuya T, Sakamoto N, Itoh H, Watanabe S. Correlation of heat shock protein expression to gender difference in development of stress-induced gastric mucosal injury in rats. J Clin Biochem Nutr. 2010 Jul;47(1):64-73. 2010 |
| 63 | Takamiya S, Fukuda K, Nakamura T, Aoki T, Sugiyama H. Paragonimus westermani possesses aerobic and anaerobic mitochondria in different tissues, adapting to fluctuating oxygen tension in microaerobic habitats. Int J Parasitol. Dec;40(14):1651-8. 2010 |
| 64 | Takamura S, Tsuji-Kawahara S, Yagita H, Akiba H, Sakamoto M, Chikaishi T, Kato M, Miyazawa M. Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors. J Immunol. May 1;184(9):4696-707. 2010 |
| 65 | Takeichi N, Yanagisawa S, Kaneyama T, Yagita H, Jin YH, Kim BS, Koh CS. Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int Immunol. Sep;22(9):729-38. 2010 |
| 66 | Tanaka K, Yoshikawa N, Kudo N, Negishi Y, Shimizu T, Hayata N. A need for play specialists in Japanese children's wards. Paediatr Nurs. Jul;22(6):31-2. 2010 |
| 67 | Tasew G, Nylén S, Lieke T, Lemu B, Meless H, Ruffin N, Wolday D, Asseffa A, Yagita H, Britton S, Akuffo H, Chiodi F, Eidsmo L. Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration. PLoS Negl Trop Dis. Oct 12;4(10):e844. 2010 |
| 68 | Tomoyasu T, Tabata A, Hiroshima R, Imaki H, Masuda S, Whiley RA, Aduse-Opoku J, Kikuchi K, Hiramatsu K, Nagamune H. Role of catabolite control protein A in the regulation of intermedilysin production by Streptococcus intermedius. Infect Immun. Sep;78(9):4012-21. 2010 |
| 69 | Torii H, Nakagawa H.Japanese Infliximab Study investigators. Infliximab monotherapy in Japanese patients with moderate-to-severe plaque psoriasis and psoriatic arthritis. A randomized, double-blind, placebo-controlled multicenter trial. J Dermatol Sci. Jul;59(1):40-9. 2010 |
| 70 | Tsubakishita S, Kuwahara-Arai K, Baba T, Hiramatsu K. Staphylococcal cassette chromosome mec-like element in Macrococcus caseolyticus. Antimicrob Agents Chemother. Apr;54(4):1469-75. 2010 |
| 71 | Tsubakishita S, Kuwahara-Arai K, Sasaki T, Hiramatsu K. Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. Antimicrob Agents Chemother. Oct;54(10):4352-9. 2010 |
| 72 | Uehara Y, Takahashi T, Yagoshi M, Shimoguchi K, Yanai M, Kumasaka K, Kikuchi K. Liver abscess of Actinomyces israelii in a hemodialysis patient: case report and review of the literature. Intern Med. 2010;49(18):2017-20. 2010 |
| 73 | Ueyama H, Yao T, Nakashima Y, Hirakawa K, Oshiro Y, Hirahashi M, Iwashita A, Watanabe S. Gastric adenocarcinoma of fundic gland type (chief cell predominant type): proposal for a new entity of gastric adenocarcinoma. Am J Surg Pathol. May;34(5):609-19. 2010 |
| 74 | Vu AT, Baba T, Chen X, Le TA, Kinoshita H, Xie Y, Kamijo S, Hiramatsu K, Ikeda S, Ogawa H, Okumura K, Takai T. Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes through the Toll-like receptor 2-Toll-like receptor 6 pathway. J Allergy Clin Immunol. Nov;126(5):985-93, 993.e1-3. 2010 |
| 75 | Wada M, Nagata S, Saito M, Shimizu T, Yamashiro Y, Matsuki T, Asahara T, Nomoto K. Effects of the enteral administration of Bifidobacterium breve on patients undergoing chemotherapy for pediatric malignancies. Support Care Cancer. Jun;18(6):751-9. 2010 |
| 76 | Yamaguchi K, Kawahara T, Kumakura S, Hua J, Kugimiya T, Nagaoka I, Inada E. Effect of olprinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats. Shock. Apr;33(4):436-41. 2010 |
英文原著（2009年）
| 1 | Barnor JS, Habu Y, Yamamoto N, Miyano-Kurosaki N, Ishikawa K, Yamamoto N, Takaku H. Inhibition of HIV-1 replication by long-term treatment with a chimeric RNA containing shRNA and TAR decoy RNA. Antiviral Research. Aug;83(2):156-64. 2009 |
| 2 | Dewan MZ, Tomita M, Katano H, Yamamoto N, Ahmed S, Yamamoto M, Sata T, Mori N, Yamamoto N. An HIV protease inhibitor, ritonavir targets the nuclear factor-kappaB and inhibits the tumor growth and infiltration of EBV-positive lymphoblastoid B cells. Int J Cancer. 1;124(3):622-9. 2009 |
| 3 | Fukumura Y, Masaoka A, Naito T, Kimura M, Yao T. A case of non-invasive serous adenocarcinoma at unilateral fimbria with spread to the peritoneal/uterine cavity: case report. Diagn Pathol. 4:43-46 2009 |
| 4 | Han X, Ito T, Takeuchi F, Ma XX, Takasu M, Uehara Y, Oliveira DC, de Lencastre H, Hiramatsu K. Identification of a novel variant of staphylococcal cassette chromosome mec, type II.5, and Its truncated form by insertion of putative conjugative transposon Tn6012. Antimicrob Agents Chemother. Jun;53(6):2616-9. 2009 |
| 5 | Hongo I, Baba T, Oishi K, Morimoto Y, Ito T, Hiramatsu K. Phenol-soluble modulin alpha 3 enhances the human neutrophil lysis mediated by Panton-Valentine leukocidin. J Infect Dis. Sep 1;200(5):715-23. 2009 |
| 6 | Katayama Y, Murakami-Kuroda H, Cui L, Hiramatsu K. Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. Antimicrob Agents Chemother. Aug;53(8):3190-6. 2009 |
| 7 | Koikawa, N., Nakamura, A., Nagaoka I., Aoki, K., Sawaki, K., Suzuki, Y. Delayed-onset muscle injury and its modification by wheat gluten hydrolysate. Nutrition May 25: 493-498 2009 |
| 8 | Komatsu M, Tajima Y, Ito T, Yamashiro Y, Hiramatsu K. Use of a sensitive chemiluminescence-based assay to evaluate the metabolic suppression activity of linezolid on methicillin-resistant Staphylococcus aureus showing reduced susceptibility to vancomycin. J Microbiol Biotechnol. Jul;19(7):734-42. 2009 |
| 9 | Matoba K, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Inaoka DK, Kita K, Harada S. Crystallization and preliminary X-ray analysis of aspartate transcarbamoyrase from the parasitic protist Trypanosoma cruzi. Acta Crystallogr, 65F, 933-936 2009 |
| 10 | Murakami T, Obata T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I. Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. Int Immunol. Aug;21(8):905-12. 2009 |
| 11 | Niyonsaba F, Nagaoka I, Ogawa H, Okumura K Multifunctional antimicrobial proteins and peptides: natural activators of immune systems. Curr Pharm. Des 15:2393-2413, 2009 |
| 12 | Ochiai T, Nishimura K, Watanabe T, Kitajima M, Tsuji M, Nakatani A, Nakayama N, Marusasa T, Mashiko S, Nagaoka I, Futagawa S. Evaluation of the individual 50% inhibitory are under the concentration curve of 5-fluorouracil based on the collagen gel droplet embedded culture drug sensitivity test in colorectal cancer. Mol Med Reports May 2(3):405-409 2009 |
| 13 | Ohba K, Ryo A, Dewan MZ, Nishi M, Naito T, Qi X, Inagaki Y, Nagashima Y, Tanaka Y, Okamoto T, Terashima K, Yamamoto N. Follicular dendritic cells activate HIV-1 replication in monocytes/macrophages through a juxtacrine mechanism mediated by P-selectin glycoprotein ligand 1. J Immunol. Jul 183; 524-532 2009 |
| 14 | Ohtsuka M, Kikuchi K, Shimizu K, Takahashi N, Ono Y, Sasaki T, Hiramatsu K. Emergence of quinolone-resistant Bordetella pertussis in Japan. Antimicrob Agents Chemother. Jul;53(7):3147-9. 2009 |
| 15 | Ohtsuka M, Kikuchi K, Shundo K, Okada K, Higashide M, Sunakawa K, Hiramatsu K. Improved selective isolation of Bordetella pertussis by use of modified cyclodextrin solid medium. J Clin Microbiol. Dec;47(12):4164-7. 2009 |
| 16 | Okuda D, Yomogida S, Kuwahara-Arai K, Hitamatsu K, Tamura H, Ohshima T, Maeda N, Nagaoka I. Augmentation of the antimicrobial activities of guinea pig cathelicidin CAP11-derived peptides by amino acid substitutions. Int J Mol Med. 2009 Apr;23(4):501-8. 2009 |
| 17 | Watanabe S, Ito T, Sasaki T, Li S, Uchiyama I, Kishii K, Kikuchi K, Skov RL, Hiramatsu K. Genetic diversity of staphylocoagulase genes (coa): insight into the evolution of variable chromosomal virulence factors in Staphylococcus aureus. PLoS One. May 27;4(5):e5714. 2009 |
| 18 | Yoshimura M, Sakamoto K, Tsuruta A, Yamamoto T, Ishida K, Yamaguchi H, Nagaoka I. Evaluation of the effect of glucosamine administration on biomarkers for cartilage and bone metabolism in soccer players. Int J Mol Med. 2009 Oct;24(4):487-94. 2009 |
英文原著（2008年）
| 1 | Hayashi Y, Okazaki T, Kobayashi H, Lane GJ, Yamataka A. Shunt conversion before bladder augmentation. Asian J Surg. Oct;31(4):207-10. 2008 |
| 2 | Takahashi T, Okazaki T, Kato Y, Watoyou H, Lane GJ, Kobayashi H, Segawa O, Kameoka S, Yamataka A. Laparoscopy-assisted Percutaneous Endoscopic Gastrostomy. Asian J Surg. Oct;31(4):204-6. 2008 |
英文原著（2007年）
| 1 | Chen, X. Niyonsaba F, Ushio H, Hara M, Yokoi H, Matsumoto K, Saito H, Nagaoka I, Ikeda S, Okumura K, Ogawa H. Antimicrobial peptides human beta-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability. Eur. J. Immunol. 37:434-444, 2007. |
| 2 | Fukushima, A., T. Sumi, K. Fukuda, N. Kumagai, T. Nishida, H. Akiba, K. Okumura, H. Yagita, and H. Ueno. Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis. Biochem Biophys Res Commun 353:211-216 . 2007 |
| 3 | Ichikawa S, Ishihara M, Okazaki T, Warabi K, Kato Y, Hori S, Lane GJ , Hiramatsu K, Inada E, Kobayashi H, Yamataka A Prospective study of antibiotic protocols for managing surgical site infections in children. J Pediatr Surg. Jun;42(6):1002-7; discussion 1007. 2007 |
| 4 | Kondo Y, Ito T, Ma XX, Watanabe S, Kreiswirth BN, Etienne J, Hiramatsu K. Combination of multiplex PCRs for SCCmec type assignment: Rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob Agents Chemother 51:264-274. 2007 |
| 5 | Kuroda H, Kuroda M, Cui L, Hiramatsu K. Subinhibitory concentrations of beta-lactam induce haemolytic activity in Staphylococcus aureus through the SaeRS two-component system. FEMS Microbiol Lett. 268:98-105. 2007 |
| 6 | Makiuchi T, Nara T, Annoura T, Hashimoto T, Aoki T. Occurrence of multiple, independent gene fusion events for the fifth and sixth enzymes of pyrimidine biosynthesis in different eukaryotic groups. Gene. 2007 Jun 1;394(1-2):78-86. 2007 |
| 7 | Marusasa T, Miyano G, Kato Y, Yanai T, Okazaki T, Ichikawa S, Lane GJ, Yamataka A. New primary management for appendiceal masses in children; laparoscopic drainage. J Laparoendosc Adv Surg Tech A. Aug;17(4):497-500. 2007 |
| 8 | Miyano G, Yanai T, Okazaki T, Kobayashi H, Lane GJ, Yamataka A. Laparoscopy-assisted stoma closure. J Laparoendosc Adv Surg Tech A. Jun;17(3):395-8. 2007 |
| 9 | Murakami, T. Yomogida S, Someya A, Kuwahara-Arai K, Tamura H, Nagaoka I. Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes. FEBS Lett. 581: 140-144, 2007. |
| 10 | Nara T, Iizumi K, Ohmae H, Sy OS, Tsubota S, Inaba Y, Tsubouchi A, Tanabe M, Kojima S, Aoki T. Antibody isotype responses to paramyosin, a vaccine candidate for schistosomiasis, and their correlations with resistance and fibrosis in patients infected with Schistosoma japonicum in Leyte, The Philippines. Am J Trop Med Hyg , 76, 384-391. 2007 |
| 11 | Niyonsaba, F., H. Ushio, N. Nakano, W. Ng, K. Sayama, K. Hashimoto, I. Nagaoka, K. Okumura, and H. Ogawa. Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. J Invest Dermatol 127:594-604. 2007 |
| 12 | Ochiai, T. Nishimura K, Noguchi H, Watanabe T, Kitajima M, Konishi N, Sato G, Nagaoka I, Futagawa S. Evaluation of 5-fluorouracil applicability by the collagen gel droplet embedded drug sensitivity test with area under the curve analysis. Anticancer. Drugs 18: 17-21, 2007. |
| 13 | Okazaki T, Iwatani S, Yanai T, Kobayashi H, Kato Y, Marusasa T, Lane GJ, Yamataka A. Treatment of lymphangioma in children: our experience of 128 cases. J Pediatr Surg. 2007 Feb;42(2):386-9. |
| 14 | Sakuma, M., K. Hatsushika, K. Koyama, R. Katoh, T. Ando, Y. Watanabe, M. Wako, M. Kanzaki, S. Takano, H. Sugiyama, Y. Hamada, H. Ogawa, K. Okumura, and A. Nakao. TGF-beta type I receptor kinase inhibitor down-regulates rheumatoid synoviocytes and prevents the arthritis induced by type II collagen antibody. Int Immunol 19:117-126 . 2007 |
| 15 | Sasaki T, Kikuchi K, Tanaka Y, Takahashi N, Kamata S, Hiramatsu K. Methicillin-Resistant Staphylococcus pseudintermedius in a Veterinary Teaching Hospital. J Clin Microbiol. 45:1118-1125. 2007 |
| 16 | Tabe, Y. Jin L, Tsutsumi-Ishii Y, Xu Y, McQueen T, Priebe W, Mills GB, Ohsaka A, Nagaoka I, Andreeff M, Konopleva M. Activation of Integrin-Linked Kinase Is a Critical Prosurvival Pathway Induced in Leukemic Cells by Bone Marrow-Derived Stromal Cells. Cancer Res. 67:684-694, 2007 |
| 17 | Tamura T, Kobayashi H, Yamataka A, Lane GJ, Koga H, Miyano T. Inchin-ko-to prevents medium-term liver fibrosis in postoperative biliary atresia patients. Pediatr Surg Int. Apr;23(4):343-7. 2007 |
| 18 | Tsuchihashi, H., T. Hasegawa, K. Sumiyoshi, H. Ogawa, S. Ikeda, T. Ando, A. Nakao, and K. Okumura. TWEAK inhibits TGF-beta-induced contraction of normal and keloid fibroblast-embedded collagen gel. J Dermatol Sci 45:216-218. 2007 |
| 19 | Wang C, Shoji H, Sato H, Nagata S, Ohtsuka Y, Shimizu T, Yamashiro Y. Effects of oral administration of Bifidobacterium breve on fecal lactic acidand short-chain fatty acids in low-birth-weight infants. J Pediatr Gastro Hepato Nutri, 44: 252-7, 2007 |
| 20 | Watanabe S, Ito T, Morimoto Y, Takeuchi F, Hiramatsu K. Precise excision and self-integration of a composite transposon as a model for spontaneous large-scale chromosome inversion/deletion of the Staphylococcus haemolyticus clinical strain JCSC1435. J Bacteriol. 189:2921-2925. 2007 |
英文原著（2006年）
| 1 | Bae T, Baba T, Hiramatsu K, Schneewind O. Prophages of Staphylococcus aureus Newman and their contribution to virulence. Mol Microbiol 62:1035-1047. 2006 |
| 2 | Chen X, Niyonsaba F, Ushio H, Nagaoka I, Ikeda S, Okumura K, Ogawa H. Human cathelicidin LL-37 increases vascular permeability in the skin via mast cell activation, and phosphorylates MAP kinase p38 and ERK in mast cells. J Dermatol Sci. 43: 63-6, 2006. |
| 3 | Cheuk, A. T., L. Chan, B. Czepulkowski, S. A. Berger, H. Yagita, K. Okumura, F. Farzaneh, G. J. Mufti, and B. A. Guinn. Development of a whole cell vaccine for acute myeloid leukaemia. Cancer Immunol Immunother 55:68-75. 2006 |
| 4 | Chongtrakool P, Ito T, Ma XX, Kondo Y, Trakulsomboon S, Tiensasitorn C, Jamklang M, Chavalit T, Song JH, Hiramatsu K Staphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries: a proposal for a new nomenclature for SCCmec elements. Antimicrob Agents Chemother 50:1001-1012, 2006. |
| 5 | Cui L, Iwamoto A, Lian J-Q, Neoh Hui-min, Maruyama T, Horikawa Y and Hiramatsu K. Novel Mechanism of Antibiotic Resistance Originating in Vancomycin-Intermediate Staphylococcus aureus. Antimicrob Agents Chemother 50:428-38, 2006 |
| 6 | Cui L, Tominaga E, Neoh Hui-min, and Hiramatsu K. Correlation between Reduced Daptomycin Susceptibility and Vancomycin. Resistance in Vancomycin-Intermediate Staphylococcus aureus. Antimicrob Agents Chemother 50:1079-1082, 2006 |
| 7 | Fan P, Gao T, Li M, Liao W, Fu M, Liu Y and Ikeda S. A case of impetigo herpetiformis associated with intrahepatic cholestasis of pregnancy. J Dermatol. 33: 563-6, 2006. |
| 8 | Fujii T, Iida Y, Yomogida M, Ikeda K, Haga T, Jikumaru Y, Ninami M, Nishimura N, Kodera Y, Inada Y, Shirai T, Hirose S, and Nishimura H. Genetic control of the spontaneous activation of CD4+ Th cells in systemic lupus erythematosus-prone (NZB x NZW) F1 mice. Genes Immun. 7:647-654, 2006. |
| 9 | Fujii T, Ohtsuka Y, Lee T, Kudo T, Shoji H, Sato H, Nagata S, Shimizu T, Yamashiro Y. Bifidobacterium breve enhances TGF-b signaling by regulatingSMAD7 expression in preterm infants. J Pediatr Gastroenterol Nutr 43: 83-8, 2006 |
| 10 | Hamano Y, Tsukamoto K, Abe M, Sun G, D, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Ogawara A, Tachikawa H, Nishimura H, Tokunaga K, Hirose S, and Suzuki K. Genetic dissection of vasculitis, myeloperoxidase-specific antineutrophil cytoplasmic autoantibody production, and renal traits in spontaneous crescentic glomerulonephritis-forming/Kinjo mice. J. Immunol. 176:3662-3673, 2006. |
| 11 | Haruna K, Shiraki Y, Hiruma M, Ikeda S, Kawasaki M. A case of lymphangitic sporotrichosis occurring on both forearms with a published work review of cases of bilateral sporotrichosis in Japan. J Dermatol. 33: 364-7, 2006. |
| 12 | Hasegawa T, Matsukura T, Mizuno Y, Suga Y, Ogawa H and Ikeda S. Clinical trial of a laser device called fractional photothermolysis system for acne scars. J Dermatol. 33:623-7, 2006. |
| 13 | Hayashi Y, Yamataka A, Kaneyama K, Kato Y, Yanai T, Kobayashi H, Lane GJ, Miyano T. Review of 86 myelodysplasia patients with neurogenic bladder who had sigmoidocolocystoplasty followed-up for more than 10 years. J Urol 176:1806-1809, 2006 |
| 14 | Hirose S, Jiang Y, Nishimura H, and Shirai T. Significance of MHC class II haplotypesand IgG Fc receptors in SLE. Springer Seminars in Immnopathol. 28:163-174, 2006. |
| 15 | Hori, J., M. Wang, M. Miyashita, K. Tanemoto, H. Takahashi, T. Takemori, K. Okumura, H. Yagita, and M. Azuma. B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts. J Immunol 177:5928-5935. 2006 |
| 16 | Hua, J. et al.: Inhibitory effects of oral glucosamine administration on platelet activation in guinea pigs. Inflamm. Regener. 26: 446-452, 2006. |
| 17 | Iizumi K, Mikami Y, Hashimoto M, Nara T, Hara Y, Aoki T. Molecular cloning and characterization of ouabain-insensitive Na+-ATPase in the parasitic Protist, Trypanosoma cruzi. Biochim Biophys Acta-Biomembranes , 1758, 738-746. 2006 |
| 18 | Inukai, T., X. Zhang, M. Goto, K. Hirose, K. Uno, K. Akahane, A. Nemoto, K. Goi, H. Sato, K. Takahashi, H. Honna, K. Kagami, K. Nakamoto, H. Yagita, K. Okumura, T. Koyama-Okazaki, S. Nakazawa, and K. Sugita. Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand: a possible mechanism for poor sensitivity to antitumor immunity. Leukemia 20:2119-2129. 2006 |
| 19 | Kamata, K., S. Kamijo, A. Nakajima, A. Koyanagi, H. Kurosawa, H. Yagita, and K. Okumura. Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis. J Immunol 177:6433-6439. 2006 |
| 20 | Kamijo, S., A. Nakajima, K. Ikeda, K. Aoki, K. Ohya, H. Akiba, H. Yagita, and K. Okumura. Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody. Biochem Biophys Res Commun 347:124-132. 2006 |
| 21 | Kanai, T., K. Uraushihara, T. Totsuka, Y. Nemoto, R. Fujii, T. Kawamura, S. Makita, D. Sawada, H. Yagita, K. Okumura, and M. Watanabe. Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis. J Gastroenterol Hepatol 21:1136-1142. 2006 |
| 22 | Kato Y, Yamtaka A, Okazaki T, Yanai T, Lane GJ, Kobayashi H, Miyano T. Surgical treatment and outcomeof mega-hydronephrosis due to pelviuteric jundotion stenosis. Pediatr Surg Int 22: 911-913, 2006 |
| 23 | Kikuchi, Y., T. Takai, M. Ota, T. Kato, K. Takeda, K. Mitsuishi, S. Ikeda, K. Okumura, and H. Ogawa. Application of immunoreaction enhancer solutions to an enzyme-linked immunosorbent assay for antigen-specific IgE in mice immunized with recombinant major mite allergens or ovalbumin. Int Arch Allergy Immunol 141:322-330. 2006 |
| 24 | Kikuchi, Y., T. Takai, T. Kuhara, M. Ota, T. Kato, H. Hatanaka, S. Ichikawa, T. Tokura, H. Akiba, K. Mitsuishi, S. Ikeda, K. Okumura, and H. Ogawa. Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses. J Immunol 177:1609-1617. 2006 |
| 25 | Komatsu N, Suga Y, Saijoh K, Liu AC, Khan S, Mizuno Y, Ikeda S, Wu HK, Jayakumar A, Clayman GL, Shirasaki F, Takehara K, Diamandis EP. Elevated human tissue kallikrein levels in the stratum corneum and serum of peeling skin syndrome-type B patients suggests an over-desquamation of corneocytes. J Invest Dermatol. 126:2338-42, 2006. |
| 26 | Nakano N, Shiraki Y, Hiruma M, Ikeda S, Sugita T. A Chinese-Japanese boy with black dot ringworm due to Trichophyton violaceum. J Dermatol. 33: 165-8, 2006. |
| 27 | Lin Q, Xiu Y, Jiang Y, Tsurui H, Nakamura K, Kodera S, Ohtsuji M, Ohtsuji N, Shiroiwa W, Tsukamoto K, Amano H, Amano E, Kinoshita K, Sudo K, Nishimura H, Izui S, Shirai T, and Hirose S. Genetic Dissection of the Effects of Stimulatory and Inhibitory IgG Fc Receptors on Murine Lupus. J. Immunol. 177:1646-1654, 2006. |
| 28 | Ma XX, Ito T, Chongtrakool P, Hiramatsu K. Molecular epidemiology of Japanese hospital MRSA 1979-85. -Predominance of Panton-Valentine leukocidin positive clones. J Clin Microbiol 44:4515-4527. 2006 |
| 29 | Maeda, K., C. Nishiyama, T. Tokura, H. Nakano, S. Kanada, M. Nishiyama, K. Okumura, and H. Ogawa. FOG-1 represses GATA-1-dependent FcepsilonRI beta-chain transcription: transcriptional mechanism of mast-cell-specific gene expression in mice. Blood 108:262-269. 2006 |
| 30 | Mizuno Y, Suga Y, Haruna K, Muramatsu S, Hasegawa T, Kohroh K, Shimizu T, Komatsu N, Ogawa H and Ikeda S. A case of Japanese neonate with congenital ichthyosiform erythroderma diagnosed as Netherton syndrome. Clin Exp Dermatol. 31: 677-80, 2006. |
| 31 | Mizuno Y, Suga Y, Hasegawa T, Haruna K, Kohroh K, Ogawa H, Ikeda S, Shimizu T, Komatsu N. A case of peeling skin syndrome successfully treated with topical calcipotriol. J Dermatol. 33:430-2, 2006. |
| 32 | Nagaoka, I. Tamura H, Hirata M. An antimicrobial cathelicidin peptide, human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPRL1 and P2X7. J. Immunol. 176: 3044-52, 2006 |
| 33 | Nakajima, A., S. Komazawa-Sakon, M. Takekawa, T. Sasazuki, W. C. Yeh, H. Yagita, K. Okumura, and H. Nakano. An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway. Embo J 25:5549-5559. 2006 |
| 34 | Nakamura K, Sugawara Y, Sawabe K. Ohashi A, Tsurui H, Xiu Y, Ohtsuji M, Lim Q, Nishimura H, Hasegawa H, and Hirose S. Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels. J. Neuroscience 26:530-534, 2006. |
| 35 | Nakamura T, Sekigawa I, Ogasawara H, Mitsuishi K, Hira K, Ikeda S, Ogawa H. Expression of DNMT-1 in patients with atopic dermatisis. Arch Dermatol Res. 298: 253-6, 2006. |
| 36 | Nakamura, T., Y. Hirasawa, T. Takai, K. Mitsuishi, M. Okuda, T. Kato, K. Okumura, S. Ikeda, and H. Ogawa. Reduction of skin barrier function by proteolytic activity of a recombinant house dust mite major allergen Der f 1. J Invest Dermatol 126:2719-2723. 2006 |
| 37 | Nakano N, Hiruma M, Shiraki Y, Chen X, Porgpermdee S and Ikeda S. Combination of pulse therapy with terbinafine tablets and topical terbinafine cream for the treatment of dermatophyte onchomycosis: a pilot study. J Dermatol. 33: 753-8, 2006. |
| 38 | Ochiai T, Nishimura K, Noguchi H, Kitajima M, Tsuruoka Y, Takahashi Y, Tsukada A, Watanabe E, Nagaoka I, Futagawa S. Prognostic impact of orotate phosphoribosyl transferase activity in resectable colorectal cancers treated by 5-fluorouracil-based adjuvant chemotherapy. J. Surg. Oncol. 94: 45-50, 2006. |
| 39 | Ochiai, T. Nishimura K, Noguchi H, Kitajima M, Tsukada A, Watanabe E, Nagaoka I, Futagawa S. Prognostic impact of orotate phosphoribosyl transferase among 5-fluorouracil metabolic enzymes in resectable colorectal cancers treated by oral 5-fluorouracil-based adjuvant chemotherapy. Int. J. Cancer 118: 3084-3088, 2006. |
| 40 | Oikawa, T., Y. Kamimura, H. Akiba, H. Yagita, K. Okumura, H. Takahashi, M. Zeniya, H. Tajiri, and M. Azuma. Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease. J Immunol 177:4281-4287. 2006 |
| 41 | Okuda, D. Yomogida S, Tamura H, Nagaoka I. Determination of the antibacterial and LPS-neutralizing regions of guinea pig neutrophil cathelicidin peptide CAP11. Antimicrob. Agents Chemother. 50, 2602-2607, 2006. |
| 42 | Ota, A. Yonemoto H, Someya A, Itoh S, Kinoshita K, Nagaoka I. Changes in matrix metalloproteinase 2 activities in amniochorions during premature rupture of membranes. J. Soc. Gynecol. Investig. 13: 592-597, 2006. |
| 43 | Porgpermdee S, Takagi A, Mayuzumi N, Ogawa H, Ikeda S, Nakamura S. Expression of SERCA2 (Darier's disease gene product) in acantholytic dermatoses. J Dermatol Sci. 43: 146-9, 2006 |
| 44 | Sariego I, Annoura T, Nara T, Hashimoto M, Tsubouchi A, Iizumi K, Makiuchi T, Murata E, Kita K, Aoki T Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase isoforms. Parasitol Int , 55, 11-16. 2006 |
| 45 | Sato, T. Iwabuchi K, Nagaoka I, Adachi Y, Ohno N, Tamura H, Seyama K, Fukuchi Y, Nakayama H, Yoshizaki F, Takamori K, Ogawa H. Induction of human neutrophil chemotaxis by Candida albicans-derived beta-1,6-long glycoside side-chain-branched beta-glucan. J. Leukoc. Biol. 80: 204-211, 2006. |
| 46 | Shirai T and Hirose S. Molecular pathogenesis of SLE. Springer Seminars in Immunopathol. 28:79-82, 2006. |
| 47 | Shiraki Y, Hiruma M, Hirose N, Sugita T and Ikeda S. A nationwide survey of Trichophyton tonsurans infection among combat sport club members in Japan using a guestionnaire form and the hairbrush method. J Am Acad Dermatol. 54: 622-6, 2006. |
| 48 | Shiraki Y, Hiruma M, Kano R, Miyamoto C and Ikeda S. Case of tinea capitis caused by Trichophyton mentagrophytes (molecular type Arthroderma benhamiae): prevalence of a new zoonotic fungal infection in Japan. J Dermatol. 33: 504-6, 2006. |
| 49 | Shiraki Y, Hiruma M, Matsuba Y, Kano R, Makimura K, Ikeda S, Ogawa H. A case of tinea corporis caused by Arthroderma benhamiae (teleomorph of Tinea mentagrophytes) in a pet shop employee. J Am Acad Dermatol. 55: 153-4, 2006. |
| 50 | Shiraki Y, Ishibashi Y, Hiruma M, Nishikawa A and Ikeda S. Cytekine secretion profiles of human keratinocytes during Trichophyton tonsurans and Arthroderma benhamiae infections. J Med Microbiol. 55: 1175-85, 2006. |
| 51 | Shiroiwa W, Tsukamoto K, Ohtsuji M, Lin Q, Ida A, Kodera S, Ohtsuji Nishimura H, Tsurui H, Kinoshita K, Nishimura H, Shirai T, and Hirose S. IL-4Ra polymorphism in regulation of IL-4 synthesis by T cells: implication in susceptibility to a subset of murine lupus. Int. Immunol. 19:175-183, 2006. |
| 52 | Someya, A. Moss J, Nagaoka I. Involvement of a guanine nucleotide-exchange protein, ARF-GEP1 0 0/BRAG2a in the apoptotic cell death of monocytic phagocytes. J. Leukoc. Biol. 80: 915-921, 2006. |
| 53 | Tabe, Y. Konopleva M, Kondo Y, Contractor R, Jin L, Ruvolo V, Tsutsumi-Ishii Y, Miyake K, Miyake N, Ohsaka A, Nagaoka I, Issa JP, Andreeff M. PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter. Ann. Hematol. 85: 689-704, 2006. |
| 54 | Tabe, Y. Konopleva M, Contractor R, Munsell M, Schober WD, Jin L, Tsutsumi-Ishii Y, Nagaoka I, Igari J, Andreeff M. Upregulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells. Blood. 107: 1546-1554, 2006. |
| 55 | Takagi A, Nishiyama C, Kanada S, Niwa Y, Fukuyama K, Ikeda S, Okumura K, Ogawa H. Prolonged MHC class II expression and CIITA transcription in human keratinocytes. Biochem Biophys Res Commun. 25: 388-93, 2006. |
| 56 | Takagi, A., C. Nishiyama, S. Kanada, Y. Niwa, K. Fukuyama, S. Ikeda, K. Okumura, and H. Ogawa. Prolonged MHC class II expression and CIITA transcription in human keratinocytes. Biochem Biophys Res Commun 347:388-393. 2006 |
| 57 | Takai, T., E. Mizuuchi, Y. Kikuchi, T. Nagamune, K. Okumura, and H. Ogawa. Glycosylation of recombinant proforms of major house dust mite allergens Der p 1 and Der f 1 decelerates the speed of maturation. Int Arch Allergy Immunol 139:181-187. 2006 |
| 58 | Uno, T., K. Takeda, Y. Kojima, H. Yoshizawa, H. Akiba, R. S. Mittler, F. Gejyo, K. Okumura, H. Yagita, and M. J. Smyth. Eradication of established tumors in mice by a combination antibody-based therapy. Nat Med 12:693-698. 2006 |
| 59 | Usui, Y., H. Akiba, M. Takeuchi, T. Kezuka, A. Takeuchi, T. Hattori, Y. Okunuki, T. Yamazaki, H. Yagita, M. Usui, and K. Okumura. The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis. Eur J Immunol 36:3071-3081. 2006 |
| 60 | Yomogida, S. et al. Effect of glucosamine on interleukin-8 production from human colonic epithelial cell cline. Inflamm. Regener. 26: 513-518, 2006. |
英文原著（2005年）
| 1 | Akiba, H., K. Takeda, Y. Kojima, Y. Usui, N. Harada, T. Yamazaki, J. Ma, K. Tezuka, H. Yagita, and K. Okumura. 2005. The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo. J Immunol 175:2340-2348 |
| 2 | Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T. The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anae robic, parasitic conditions. J Mol Evol, 60, 113-127, 2005 |
| 3 | Aramaki, O., F. Inoue, T. Takayama, M. Shimazu, M. Kitajima, Y. Ikeda, K. Okumura, H. Yagita, N. Shirasugi, and M. Niimi. 2005. Interleukin-10 but not transforming growth factor-? is essential for generation and suppressor function of regulatory cells induced by intratracheal delivery of alloantigen. Transplantation 79:568-576. |
| 4 | Aramaki, O., F. Inoue, T. Takayama, M. Shimazu, M. Kitajima, Y. Ikeda, K. Okumura, H. Yagita, N. Shirasugi, and M. Niimi. 2005. Various costimulatory pathways are essential for induction of regulatory cells by intratracheal delivery of alloantigen. Transplant Proc 37:1934-1936. |
| 5 | Bashuda, H., M. Kimikawa, K. Seino, Y. Kato, F. Ono, A. Shimizu, H. Yagita, S. Teraoka, and K. Okumura. 2005. Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates. J Clin Invest 115:1896-1902. |
| 6 | Boyce JM, Cookson B, Christiansen K, Hori S, Vuopio-Varkila J, Kocagoz S, Oztop AY, Vandenbroucke-Grauls CM, Harbarth S, Pittet D. Meticillin-resistant Staphylococcus aureus. Lancet Infect Dis 5:653-63, 2005 |
| 7 | Chen X, Niyonsaba F, Ushio H, Okuda D, Nagaoka I, Ikeda S, Okumura K, Ogawa H. Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli. J. Dermatol. Sci. 40: 123-132, 2005 |
| 8 | Cui L, Lian JQ, Neoh HM, Reyes E, Hiramatsu K. DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus. Antimicrob Agents Chemother 49:3404-13,2005 |
| 9 | Fukumoto K, Nagaoka I, Yamataka A, Kobayashi H, Yanai T, kato Y, Miyano T. Effect of antibacterial cathelicidin peptiden CAP18/LL-37 on sepsis in neonatal rats. Pediatr Surg Int. 2005 Jan;21(1):20-4. |
| 10 | Hasegawa T, Suga Y, Mizoguchi M, Muramatsu S, Mizuno Y, Ogawa H, Kubo K, Kuroyanagi Y. An allogeneic cultured dermal substitute suitable for treating intractable skin ulcers and large skin defects prior to autologous skin grafting: three case reports. J Dermatol 32:715-20, 2005 |
| 11 | Hashimoto M, N.-Shimada J, Aoki T. Trypanosoma cruzi post-transcri ptionally upregulates and exploits cellular FLIP for inhibition of death-inducing signal. Mol Biol Cell, 16, 3521-3528, 2005 |
| 12 | Hashimoto M, Nakajima-Shimada J, Ishidoh K, Aoki T. Gene expression profiles in response to Fas stimulation in Trypanosoma cruzi-infected host cells. Int J Parasitol, 35, 1587-1594, 2005 |
| 13 | Heissig, B., S. Rafii, H. Akiyama, Y. Ohki, Y. Sato, T. Rafael, Z. Zhu, D. J. Hicklin, K. Okumura, H. Ogawa, Z. Werb, and K. Hattori. 2005. Lowdose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization. J Exp Med 202:739-750. |
| 14 | Hisata K, Kuwahara-Arai K, Yamanoto M, Ito T, Nakatomi Y, Cui L, Baba T, Terasawa M, Sotozono C, Kinoshita S, Yamashiro Y, Hiramatsu K. Dissemination of methicillin-resistant staphylococci among healthy Japanese children. J Clin Microbiol Jul;43(7):3364-72 2005 |
| 15 | Hua J, Suguro S, Hirano S, Sakamoto K, Nagaoka I. Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats. Inflamm. Res. 54: 127-132, 2005 |
| 16 | Inaoka DK, Takashima E, Osanai A, Shimizu H, Nara T, Aoki T, Harada S, Kita K. Expression, purification and crystallization of Trypa nosoma cruzi dihydroorotate dehydrogenase complexed with orotate. Acta Cryst, F61, 875-878, 2005 |
| 17 | Ishihara M, Yamataka A, Kaneyama K, Koga H, Kobayashi H, Lane GJ, Miyano T, Prospective analysis of primary modified Georgeson's laparoscopy-assisted endorectal pull-through for Hirschsprung's disease: short- to mid-term results. Pediatr Surg Int 21: 878-882, 2005 |
| 18 | Ito, T., C. Nishiyama, M. Nishiyama, H. Matsuda, K. Maeda, Y. Akizawa, R. Tsuboi, K. Okumura, and H. Ogawa. Mast cells acquire monocyte-specific gene expression and monocyte-like morphology by overproduction of PU.1. J Immunol 174:376-383, 2005. |
| 19 | Kaduka, Y., K. Takeda, M. Nakayama, K. Kinoshita, H. Yagita, and K. Okumura. TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage. Biochem Biophys Res Commun 331:384-390 2005. |
| 20 | Kanamaru, Y., K. Sumiyoshi, H. Ushio, H. Ogawa, K. Okumura, and A. Nakao. Smad3 deficiency in mast cells provides efficient host protection against acute septic peritonitis. J Immunol 174:4193-4197. 2005. |
| 21 | Kaneda, H., K. Takeda, T. Ota, Y. Kaduka, H. Akiba, Y. Ikarashi, H. Wakasugi, M. Kronenberg, K. Kinoshita, H. Yagita, and K. Okumura. ICOS costimulates invariant NKT cell activation. Biochem Biophys Res Commun 327:201-207. 2005. |
| 22 | Kato, T., T. Takai, K. Mitsuishi, K. Okumura, and H. Ogawa. 2005. Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases. J Allergy Clin Immunol 116:169-176. 2005 |
| 23 | Kawada, H., C. Nishiyama, A. Takagi, T. Tokura, N. Nakano, K. Maeda, N. Mayuzumi, S. Ikeda, K. Okumura, and H. Ogawa. Transcriptional regulation of ATP2C1 gene by Sp1 and YY1 and reduced function of its promoter in Hailey-Hailey disease keratinocytes. J Invest Dermatol 124:1206-1214, 2005 |
| 24 | Kawamura, H., H. Yagita, T. Nisizawa, N. Izumi, C. Miyaji, R. E. Vance, D. H. Raulet, K. Okumura, and T. Abo. Amelioration of acute graftversus-host disease by NKG2A engagement on donor T cells. Eur J Immunol 35:2358-2366. 2005. |
| 25 | Koga H, Yamataka A, Kobayashi H, Lane GJ, Miyano T, Median sternotomy provides excellent exposure for excising anterior mediastinal tumors in children. Pediatr Surg Int 21: 864-867, 2005 |
| 26 | Lu-Suguro JF, Hua J, Sakamoto K, Nagaoka I. Inhibitory action of glucosamine on platelet activation in guinea pigs. Inflamm. Res. 54:493-499 2005 |
| 27 | Ma XX, Galiana A, Pedreira W, Mowszowicz M, Christophersen I, Machiavello S, Lope L, Benaderet S, Buela F, Vincentino W, Albini M, Bertaux O, Constenla I, Bagnulo H, Llosa L, Ito T, Hiramatsu K. Community-acquired methicillin-resistant Staphylococcus aureus, Uruguay. Emerg Infect Dis. 11(6):973-6 2005 |
| 28 | Mayuzumi N, Ikeda S, Kawada H, Fan PS, Ogawa H. Effects of UVB irradiation, pro-inflammatory cytokines and raised extracellular calcium concentration on the expression of ATP2A2 and ATP2C1. Br J Dermatol. 2005 Apr;152(4):697-701. |
| 29 | Mayuzumi N, Ikeda S, Kawada H, Ogawa H. Effects of drugs and anticytokine antibodies on expression of ATP2A2 and ATP2C1 in cultured normal human keratinocytes. Br J Dermatol. 2005 May;152(5):920-4. |
| 30 | Mehmut M, Takeda K, Abe M., Ogara H, Hirose S, Okumura K, Fujime M. Fas ligand and TNF-related apoptosis-inducing ligand induction on infiltrating lymphocytes in bladder carcinoma by bacillus Calmette-Guerin treatment. Urol Int, 75:80-87, 2005 |
| 31 | Miyahira, Y., Y. Takashima, S. Kobayashi, Y. Matsumoto, T. Takeuchi, M. Ohyanagi-Hara, A. Yoshida, A. Ohwada, H. Akiba, H. Yagita, K. Okumura, and H. Ogawa. Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection. Infect Immun 73:7356-7365, 2005 |
| 32 | Nagaoka I, Kuwahara-Arai K, Tamura H, Hiramatsu K, Hirata M. Augmentation of the bactericidal activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by amino acid substitutions. Inflamm. Res. 54: 66-73, 2005. |
| 33 | Nakamura K, Nishimura H, Hirose S. Correlation of aggression with serum IgM level in autoimmune-prone NZB mice. Developmental Brain Res earch, 159:145-148, 2005. |
| 34 | Nakano, N., A. Nakao, K. Ishidoh, R. Tsuboi, E. Kominami, K. Okumura, and H. Ogawa. 2005. CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes. Br J Dermatol 153:37-45. |
| 35 | Nakano, N., A. Nakao, T. Uchida, N. Shirasaka, H. Yoshizumi, K. Okumura, R. Tsuboi, and H. Ogawa. 2005. Effects of arachidonic acid analogs on Fc epsilon RI-mediated activation of mast cells. Biochim Biophys Acta 1738:19-28. |
| 36 | Nakano, N., C. Nishiyama, N. Masuoka, M. Nishiyama, H. Yamane, K. Okumura, and H. Ogawa. 2005. Analysis of PU.1/ICSBP (IRF-8) complex formation with various PU.1 mutants: molecular cloning of rat Icsbp (Irf-8) cDNA. Immunogenetics 56:871-877. |
| 37 | Nakazawa, T., T. Takai, H. Hatanaka, E. Mizuuchi, T. Nagamune, K. Okumura, and H. Ogawa. 2005. Multiple-mutation at a potential ligand-binding region decreased allergenicity of a mite allergen Der f 2 without disrupting global structure. FEBS Lett 579:1988-1994. |
| 38 | Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Iizumi K, Dohmo to Y, Ono T, Aoki T. Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase activity and on the protozoan growth in mammalian cells. Parasitol Int,54, 59-64, 2005 |
| 39 | Nishiyama, C., T. Ito, M. Nishiyama, S. Masaki, K. Maeda, N. Nakano, W. Ng, K. Fukuyama, M. Yamamoto, K. Okumura, and H. Ogawa. GATA-1 is required for expression of Fc? RI on mast cells: analysis of mast cells derived from GATA-1 knockdown mouse bone marrow. Int Immunol 17:847-856, 2005. |
| 40 | Niyonsaba F, Ushio H, Nagaoka I, Okumura K, Ogawa H. The human beta -defensins (-1, -2, -3, -4) and cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK activation in primary human keratinocytes. J. Immunol. 175: 1776-1784, 2005 |
| 41 | Noguchi N, Suwa J, Narui K, Sasatsu M, Ito T, Hiramatsu K, Song JH. Susceptibilities to antiseptic agents and distribution of antiseptic-resistance genes qacA/B and smr of methicillin-resistant Staphylococcus aureus isolated in Asia during 1998 and 1999. J Med Microbiol 54(:557-65,2005 |
| 42 | Ogata M, Tutumimoto Sato K, Kunikane T, Oka K, Seki M, Urano S, Hiramatsu K, Endo T. Antibacterial activity of dipropofol and related compounds. Biol Pharm Bull 28:1120-2, 2005 |
| 43 | Okamoto, A., T. Kawamura, K. Kanbe, Y. Kanamaru, H. Ogawa, K. Okumura, and A. Nakao. 2005. Suppression of serum IgE response and systemic anaphylaxis in a food allergy model by orally administered high-dose TGF-beta. Int Immunol 17:705-712. |
| 44 | Ota, T., K. Takeda, H. Akiba, Y. Hayakawa, K. Ogasawara, Y. Ikarashi, S. Miyake, H. Wakasugi, T. Yamamura, M. Kronenberg, D. H. Raulet, K. Kinoshita, H. Yagita, M. J. Smyth, and K. Okumura. IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. Blood 106:184-192. 2005. |
| 45 | Qi Z, Wang J, Sun Z, Ma F, Zhang Q, Hirose S, Jiang Y. Polymorphism of the mouse gene for the interleukin 10 receptor alpha chain (Il10 ra) and its association with the autoimmune phenotype. Immunogenetics. 57:697-702, 2005. |
| 46 | Sampanthanarak P, Niyonsaba F, Ushio H, Nagaoka I, Ikeda S, Okumura, K, Ogawa H. The effect of antibacterial peptide human beta-defensin-2 on interleukin-18 secretion by keratinocytes. J. Dermatol. Sci. 37:188-191, 2005 |
| 47 | Sanmano B, Mizoguchi M, Suga Y, Ikeda S, Ogawa H. Engraftment of umbilical cord epithelial cells in athymic mice: in an attempt to improve reconstructed skin equivalents used as epithelial composite. J Dermatol Sci. 2005 Jan;37(1):29-39. |
| 48 | Shike T, Gohda T, Tanimoto M, Kobayashi M, Makita Y, Funabiki K, Horikoshi, Hirose S, Shirai T, Tomino Y. Chromosomal mapping of a quantitative trait locus for the development of albuminuria in diabetic KK/Ta mice. Nephrol Dial Transplant, 20:879-885, 2005 |
| 49 | Sng LH, Koh TH, Wang GC, Hsu LY, Kapi M, Hiramatsu K. Heterogeneous vancomy cin-resistant Staphylococcus aureus (hetero-VISA) in Singapore. Int J Antimicrob Agents. Feb;25(2):177-9. 2005 |
| 50 | Soo Ko K, Peck KR, Sup Oh W, Lee NY, Hiramatsu K, Song JH. Genetic differentiation of methicillin-resistant Staphylococcus aureus strains from Korea and Japan. Microb Drug Resist 11:279-86, 2005 |
| 51 | Suzuki H, Suzuki Y, Yamanaka T, Hirose S, Nishimura H, Toei J, Horikoshi S, Tomino Y. Genome-wide scan in novel IgA nephropathy model identifies susceptibility locus on murine chromosome 10, in a region sytenic to human IGAN1 on chromosome 6q22-23. J Am Soc Nephrol, 16:1289-1299, 2005 |
| 52 | Tabe Y, Konopleva M, Contractor R, Munsell M, Schober WD, Jin L, Tsutsumi-Ishii Y, Nagaoka I, Igari J, Andreeff M. Upregulation of MDR and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells. Blood. 2006 Feb 15;107(4):1546-54. Epub 2005 Oct 13. |
| 53 | Takai, T., M. Takaoka, H. Yasueda, K. Okumura, and H. Ogawa. 2005. Dilution method to refold bacterially expressed recombinant Der f 2 and Der p2 to exhibit the secondary structure and histamine-releasing activity of natural allergens. Int Arch Allergy Immunol 137:1-8. |
| 54 | Takai, T., T. Kato, H. Yasueda, K. Okumura, and H. Ogawa. Analysis of the structure and allergenicity of recombinant pro- and mature Der p1 and Der f 1: major conformational IgE epitopes blocked by prodomains. J Allergy Clin Immunol 115:555-563. 2005. |
| 55 | Takai, T., T. Kato, M. Ota, H. Yasueda, T. Kuhara, K. Okumura, and H. Ogawa. Recombinant Der p 1 and Der f 1 with in vitro enzymatic activity to cleave human CD23, CD25 and alpha1-antitrypsin, and in vivo IgE-eliciting activity in mice. Int Arch Allergy Immunol 137:194-200, 2005. |
| 56 | Takai, T., T. Kato, Y. Sakata, H. Yasueda, K. Izuhara, K. Okumura, and H. Ogawa. Recombinant Der p 1 and Der f 1 exhibit cysteine protease activity but no serine protease activity. Biochem Biophys Res Commun 328:944-952, 2005. |
| 57 | Takaya N, Katoh Y, Iwabuchi K, Hayashi I, Konishi H, Itoh S, Okumura K, Ra C, Nagaoka I, Daida H. Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor gamma-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury. J. Mol. Cell. Cardiol. 39: 856-864, 2005. |
| 58 | Takeda, K., E. Cretney, Y. Hayakawa, T. Ota, H. Akiba, K. Ogasawara, H. Yagita, K. Kinoshita, K. Okumura, and M. J. Smyth. 2005. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood 105:2082-2089. |
| 59 | Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K. Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species. J Bacteriol 187:7292-308,2005 |
| 60 | Tanaka, T., T. Ebata, A. Tajima, K. Kinoshita, K. Okumura, and H. Yagita. Beta2-microglobulin required for cell surface expression of blastocyst MHC. Biochem Biophys Res Commun 332:311-317. 2005 |
| 61 | Tokura, T., N. Nakano, T. Ito, H. Matsuda, Y. Nagasako-Akazome, T. Kanda, M. Ikeda, K. Okumura, H. Ogawa, and C. Nishiyama. Inhibitory effect of polyphenol-enriched apple extracts on mast cell degranulation in vitro targeting the binding between IgE and Fc epsilon RI. Biosci Biotechnol Biochem 69:1974-1977. 2005. |
| 62 | Torun MM, Bahar H, Demirci M, Altas K, Bagdatli Y, Kocazeybek B, Kapi M, Hiramatsu K. Two heterogeneously vancomycin-intermediate clinical isolates of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in a Turkish university hospital: brief report of asurveillance study. Int J Antimicrob Agents. Dec;26(6):508-10, 2005 |
| 63 | Totsuka, T., T. Kanai, S. Makita, R. Fujii, Y. Nemoto, S. Oshima, R. Okamoto, A. Koyanagi, H. Akiba, K. Okumura, H. Yagita, and M. Watanabe. 2005. Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells. Eur J Immunol 35:1773-1785. |
| 64 | Tsukahara, R., M. Takeuchi, H. Akiba, T. Kezuka, K. Takeda, Y. Usui, M. Usui, H. Yagita, and K. Okumura. 2005. Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation. Int Immunol 17:523-530. |
| 65 | Uchiyama N, Kabututu Z, Kubata BK, Kiuchi F, Ito M, Nakajima-Shimada J, Aoki T, Ohkubo K, Fukuzumi S, Martin SK, Honda G, Urade Y. Antichagasic activity of komaroviquinone is due to generation of reactive oxygen species catalyzed by Trypanosoma cruzi old yellow enzyme. Antimicrob Agents Chemother, 49, 5123-5126, 2005 |
| 66 | Watanabe S, Ito T, Takeuchi F, Endo M, Okuno E, Hiramatsu K. Structural comparison of ten serotypes of staphylocoagulases in Staphylococcus aureus. J Bacteriol Jun;187(11):3698-707 2005 |
| 67 | Xue, X., J. H. Piao, A. Nakajima, S. Sakon-Komazawa, Y. Kojima, K. Mori, H. Yagita, K. Okumura, H. Harding, and H. Nakano. Tumor necrosis factor alpha (TNFalpha ) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS acumulation by TNFalpha. J Biol Chem 280:33917-33925. 2005 |
| 68 | Yamabe, H., Y. Tanaka, K. Okumura, Y. Morikami, Y. Kimura, Y. Hokamura, and H. Ogawa. Electrophysiologic characteristics of verapamil-sensitive atrial tachycardia originating from the atrioventricular annulus. Am J Cardiol 95:1425-1430. 2005 |
| 69 | Yamazaki, T., H. Akiba, A. Koyanagi, M. Azuma, H. Yagita, and K. Okumura. Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production. J Immunol 175:1586-1592. 2005 |
| 70 | Zhang B, Ohtsuka Y, Fujii T, Baba H, Okada K, Shoji H, Nagata S, Shimizu T, Yamashiro Y. Immunological development of preterm infants in early infancy. Clin Exp Immunol 2005 ;140:92-6. |
| 71 | Zhang H, Yamataka A, Koga H, Kobayashi H, Lane GL, Miyano T. Bladder stone formation after sigmoidocolocystoplasty: statistical analysis of risk factors. J Pediatr Surg 40:407-411, 2005 |
Communication
| 1 | Han, X.; Ito, T.; Uehara, Y.; Zhang, M.; Hiramatsu, K. Characterization of SCCmec elements that carry ccrA3 and ccrB3 genes identified in Staphylococcus epidermidis. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS |
| 2 | Hiramatsu, K. Molecular evolution of MRSA and VISA INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS |
| 3 | Lulitanond, A.; Ito, T.; Li, S.; Han, X.; Ma, X. X.; Engchanil, C.; Chanawong, A.; Wilailackana, C.; Jiwakanon, N.; Hiramatsu, K. Identification of a variant of type IX SCCmec in ST9 MRSA strains isolated in Thailand. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS |
| 4 | Matsuo, M.; Cui, L.; Kim, J.; Hiramatsu, K. A mutation of cmk (cytidylate kinase) gene confers reduced vancomycin susceptibility in Staphylococcus aureus. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS |
| 5 | Morimoto, Y.; Igarashi, M.; Baba, T.; Hiramatsu, K. Antimicrobial activity of nybomycin against Escherichia coli. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS |
| 6 | Ishikawa, D.; Osada, T.; Sasaki, T.; Kuwahara-Arai, K.; Haga, K.; Shibuya, T.; Kodani, T.; Hiramatsu, K.; Watanabe, S. Alterations of Intestinal Microbiota in Ulcerative Colitis Patients Treated with Sequential Antibiotic Combination and Faecal Microbiota Transplantation. JOURNAL OF CROHNS & COLITIS |
| 7 | Uehara, Y.; Sasaki, T.; Hiramatsu, K.; Kawada, M.; Furuichi, M.; Imajo, E.; Sato, Y.; Anno, S. T. ST834 methicillin-resistant Staphylococcus aureus with a pathogenicity island similar to SaPIj50 among children in Saitama, Japan. Int J Antimicrob Agents. |
日本語論文
| 1 | 桑原京子、平松啓一. 臨床分離株に対するdoripenemの抗菌力. 日本化学療法雑誌 53（S-1）17 – 23 2005 |
| 2 | 伊藤輝代、平松啓一. MRSA感染症. 日本臨床 増刊号 63 Suppl 12, Dec |
| 3 | 小松充孝、田島裕、伊藤輝代、山城佑一郎、平松啓一. 化学発光および呈色試薬を用いたメチシリン耐性黄色ブドウ球菌に対するLinezolidの抗菌活性の評価. 日本化学療法学会雑誌 54:102-110. 2006 |
| 4 | 檀原高, 奥村徹, 関谷栄, 内藤俊夫, 堀賢. インフルエンザで怖い肺炎と脳症 鳥インフルエンザの予防と治療. 順天堂のやさしい医学１３かぜとインフルエンザ、順天堂大学医学部編、学生社、東京、115-139, 2006. |
| 5 | ネオフイミン、堀賢、小松充孝、小栗豊子、竹内史比古、崔龍洙、平松啓一. バンコマイシン感受性低下がMRSA血流感染症の臨床経過に及ぼす影響の検討. 順天堂医学June ; Vol. (53); 243-250. 2007 |
| 6 | 池田恵、堀賢、三澤成毅、小栗豊子、網中 真由美、李澤 康雄、坂田 梢、伊藤 輝代、平松 啓一. VanB型－バンコマイシン耐性腸球菌による局地的流行伝播の早期発見と拡散防止対策の有効性について. 環境感染 22(3):203-210. 2007 |
| 7 | 岡崎千絵、堀賢、森本景子、下嶋和代、佐瀬一洋. 医療従事者における新型インフルエンザワクチン接種後の副反応発生状況. 環境感染 25: 237-241. 2010 |
| 8 | 山本典生，中村一哉，浜本いつき，田代眞人. パンデミックインフルエンザ(H1N1)2009に対するワクチンの評価と新ワクチン開発に向けた展望. 公衆衛生, Aug 74(8):681-686. 2010 |
| 9 | 山本典生、田代眞人. 国立感染症研究所インフルエンザウイルス研究センターの紹介. 医学のあゆみ June 232(13): 1230-1232 2010 |
| 10 | 冨永英司、伊藤輝代、CHRISTOF VON EIFF、平松啓一. 黄色ブドウ球菌small colony variants出現抑制のためのアルベカシンとスルバクタム/アンピシリンの併用効果. 順天堂医学 56:339-3492010 |
| 11 | 茅野崇、菱沼知美、松尾美記、張萠、伊藤輝代、森本ゆふ、平松啓一. 市中獲得型MRSA（CA-MRSA）の高病原性に関する研究：オキサシリン高度耐性化とfudoh領域の影響. 順天堂医学 56：56-67. 2010 |
| 12 | 関根美和、馬場理、片山由紀、平松啓一. 黄色ブドウ球菌MHC様分子が貪食などの宿主免疫系に及ぼす影響について. 順天堂医学 57(3), 232-242. 2011 |
| 13 | 高橋並子、澤村正之、菊池賢、平松啓一. 多剤耐性淋菌に対するニトロフラントイン，ホスホマイシンを含む代替治療候補としての抗菌薬の感受性. 順天堂医学57(4)365-369. 2011 |
| 14 | 小野由可、菊池賢、Xun J、堀賢、平松啓一. linezolid 治療中に出現した縦隔炎患者由来 methicillin-resistant Staphylococcus aureus のlinezolid 耐性機構. 順天堂医学57(4)370-6. 2011 |
| 15 | 金京勲、伊藤輝代、平松啓一. 世界各地で分離されたVancomycin-intermediate S. aureus 46株の分子疫学的解析. 順天堂医学57(5)494-503. 2011 |
| 16 | 香本晃良, 崔龍洙、江端望、渡辺由希子、松尾美記、片山由紀、Piyamas Petcharoen、平松啓一. 黄色ブドウ球菌におけるRNAポリメラーゼ遺伝子の突然変異はLinezolidの高感受性化に関連する. 順天堂医学 58(6) 498-505. 2012 |
| 17 | 射場敏明, 村井美和, 長岡功, 田部陽子. 敗血症におけるneutrophil extracellular traps (NETs), damage-associated molecular patterns (DAMPs), そして細胞死. 日救急医会誌 24: 181-191 2013. |
| 18 | 細谷志乃、伊藤輝代、三澤成毅、吉池高志、小栗豊子、平松 啓一. 皮膚科外来患者由来 MRSA 株に見られる新規 MRSA クローンの出現状況. 感染症学雑誌 2014 Nov;88(6):840-8. |
| 19 | 三宅幸子. MAIT細胞と自己免疫. Jpn J Clin Immunol. 37(1):19-24 2014. |
| 20 | 三宅幸子. 腸内細菌と自己免疫. Jpn J Clin Immunol. 37(5):398-402 2014. |
| 21 | 三宅幸子. 自然リンパ球. 医学のあゆみ.251(6):479 2014. |
| 22 | 家田健史、桒原京子、森本ゆふ、久末伸一、伊藤輝代、堀江重郎、平松啓一. 尿路感染症主要原因菌のフルオロキノロン系抗菌薬を中心とした薬剤に対する感受性および gyrA・parC における QRDR の遺伝子変異の解析. 日本化学療法学会雑誌 2015. 63（3）:343-349 |
| 23 | 川合覚, 丹羽孝介, 川瀬三雄, 美田敏宏. STH-PAS法を活用したマラリア遺伝子診断ツールの開発. Clinical Parasitology. 26:86-9. 2015. |
| 24 | 三宅幸子. 腸内細菌と自己免疫. Keynote R・A.,3(1):14-18 2015. |
| 25 | 三宅幸子. 自己免疫疾患と腸内細菌. Medical Science Digest 41(4):146-149 2015. |
| 26 | 胡忠双, 長岡功. LPS誘導性ピロトーシスと抗菌ペプチド. 医学のあゆみ253: 1087-1091 2015. |
| 27 | 美田敏宏. 国内で遭遇する可能性のある熱帯病：確実な診断と感染防御の最新知見. 日本臨床内科医会会誌. 29(5):756-60. 2015. |
| 28 | 三宅幸子. 神経免疫. 炎症と免疫. 23(2):105 2015. |
| 29 | 三宅幸子. 自己免疫疾患と腸内細菌. 細胞 47(2):57-60 2015. |
著書
| 1 | Cui, L., and K. Hiramatsu. 2004. Vancomycin-resistant Staphylococcus aureus. in ed, by Franz-Josef Schmitz and Dr. Ad C. Fluit. MRSA. Horizon Scientific Press. |
| 2 | Kuroda, M., and K. Hiramatsu. 2004. Genome sequencing and annotation: an overview. Johnson, A., and Woodford, N., ed., Genomics, Proteomics and Clinical Bacteriology. Humana Press. |
| 3 | Baba, T.,Takeuchi, F., Kuroda, M., Yuzawa, H., Ito, T., and Hiramatsu, K. 2004. The Genome of Staphylococcus aureus. pp In Al'Aladeen, D., and Hiramatsu, K (ed). The Staphylococcus aureus: Molecular and Clinical Aspects. Eliis Harwood, London, UK. |
| 4 | Hiramatsu, K., Kuroda, M., Baba, T., and K. Okuma. 2004. Application of Genomic Information to the Diagnosis, Management and Control of Bacterial Infections: The Staphylococcus aureus model. ed.by D. Persing, et al. Diagnostic Molecular Microbiology 2nd Ed, pp407-418, ASM Press. |
| 5 | 堀 賢. 空気感染対策. 臨床微生物の基礎知識、奥住捷子、小栗豊子編、メディカ出版、東京、215-217, 2006 |
| 6 | 堀 賢： 飛沫感染対策. 臨床微生物の基礎知識、奥住捷子、小栗豊子編、メディカ出版、東京、218-220, 2006. |
| 7 | 星最智、堀 賢： 接触感染対策. 臨床微生物の基礎知識、奥住捷子、小栗豊子編、メディカ出版、東京、221-223, 2006. |
| 8 | 堀 賢： インフルエンザの診断が遅れた場合の治療・管理. インフルエンザハンドブック、富野康日己、永井厚志編、中外医学社、東京、199-204, 2006 |
| 9 | 堀 賢： 順天堂医院での取り組み、わが病院の感染対策. 木村哲編、医薬ジャーナル社、大阪、231-237, 2006. |
| 10 | 山本典生. 細胞培養法による新型インフルエンザワクチン製造におけるバイオセーフティとGMP クリーンテクノロジー 日本工業出版 22:1-5 2012. |
| 11 | 上原由紀. 白血球 感度と特異度からひもとく感染症診療のDecision Making 細川直登編, 文光堂 16-20 (368頁) 2012. |
| 12 | 仁科隆史, 中野裕康. 実験医学増刊号「活性酸素・ガス状分子による恒常性制御と疾患」 山本雅之監修, 赤池孝章, 一條秀憲, 森泰生編 羊土社, 123-129 (219頁) 2012. |
| 13 | 大塚宜一，清水俊明. 周産期診療ワークブック. 日本周産期, 新生児医学会教育, 研修委員会（編） メジカルビュー社，東京．359-361 (461頁) 2012. |
| 14 | 平松啓一. 標準微生物学第11版. 平松啓一 (監修), 中込 治 (編集), 神谷 茂 (編集), 医学書院 (688頁) 2012. |
| 15 | 山本典生, 田代眞人. 新型インフルエンザ予防接種 Q&A 小児内科 東京医学社 45, 549-551 2013. |
| 16 | 上原由紀. 企画にあたって 臨床感染症ブックレット8巻 感染症の予防や制御に必要なことを実践する. 上原由紀, 前崎繁文, 大曲貴夫編 文光堂 5（168頁） 2013. |
| 17 | 上原由紀. 感染経路別予防策（3）ー接触感染予防策ー 臨床感染症ブックレット8巻 感染症の予防や制御に必要なことを実践する. 上原由紀, 前崎繁文, 大曲貴夫編 文光堂 20-26（168頁） 2013. |
| 18 | 上原由紀. 感染対策の効果を判定するには？ 臨床感染症ブックレット8巻 感染症の予防や制御に必要なことを実践する. 上原由紀, 前崎繁文, 大曲貴夫編 文光堂 161-163（168頁） 2013. |
| 19 | 橋本宗明, 奈良武司. トリパノソーマ症． 別冊感染症症候群（第2版）、上巻 日本臨牀．日本臨牀社、大阪、650-653（812頁） 2013. |
| 20 | 美田敏宏, 北潔. 検査値を読む：寄生虫卵・虫体検査. 内科 111: 1049, 2013 南山堂 2013. |
| 21 | 山本典生, 田代眞人. 細胞培養インフルエンザワクチン Bio Clinica 北隆館 28: 41-45 2013. |
| 22 | 奈良武司監訳・訳. Section 17 原虫および蠕虫感染症：概論 Part 8 感染症 ハリソン内科学第4版（原著第18版） 福井次矢、黒川清監修、メディカル・サイエンス・インターナショナル、東京、1465-1470（3376頁） 2013. |
| 23 | 奈良武司監訳・訳. Section 18 原虫感染症 Part 8 感染症 ハリソン内科学第4版（原著第18版） 福井次矢、黒川清監修、メディカル・サイエンス・インターナショナル、東京、1471-1515（3376頁） 2013. |
| 24 | 奈良武司監訳・訳. Section 19 蠕虫感染症 Part 8 感染症 ハリソン内科学第4版（原著第18版） 福井次矢、黒川清監修、メディカル・サイエンス・インターナショナル、東京、1516-1542（3376頁） 2013. |
| 25 | 奈良武司. ヌクレオチド代謝. 岩波生物学辞典第5版 巌佐庸、倉谷滋、斎藤成也、塚谷裕一編、岩波書店、東京（2192頁） 2013. |
| 26 | Chiba A, Miyake S. Basic techniques for studies of iNKT cells and MAIT cells. Arthritis Research Methods and Protocols. Shiozawa S ed. Springer, London, 75-84 2014. |
| 27 | 山田俊幸, 大戸斉, 渥美達也, 三宅幸子, 山内一由編 免疫系のしくみと働き 新版 臨床免疫学第３版. 南江堂 1−25 (340頁) 2014. |
| 28 | 山田俊幸, 大戸斉, 渥美達也, 三宅幸子, 山内一由編 細胞表面分子とサイトカイン 新版 臨床免疫学第３版. 南江堂 1−25 (340頁) 2014. |
| 29 | 胡忠双, 村上泰介, 鈴木香, 田村弘志, 長岡功. 抗菌ペプチドLL-37によるマクロファージ系細胞のピロトーシスの制御. エンドトキシン・自然免疫研究17 －エンドトキシン・自然免疫の展開：新しい機序、診断、応用. 谷徹, 横地高志 編集, 医学図書出版, 東京, 73-75（105頁） 2014. |
| 30 | 上原由紀. バンコマイシンとテイコプラニン “実践的“抗菌薬の選び方・使い方 細川直登編, 医学書院 163−169 (221頁) 2014. |
| 31 | 上原由紀. 胆道感染症 ワンランク上の検査値の読み方・考え方–ルーチン検査から病態変化を見抜く– 本田孝行編, 医学書院 148-153（368頁） 2014. |
| 32 | 美田敏宏. マラリア/バベシア. 今日の治療指針2014. 医学書院 東京、256-7, (1900頁) 2014. |
| 33 | 渡辺純夫, 永原章仁, 北條麻理子. 消化管疾患 診療マニュアル 日本医学館（692頁） 2014. |
| 34 | Nakayama H, Iwabuchi K. Glycosphingolipid-Receptor Interactions in the Innate Immune Responses. Glycoscience Glycoscience: Biology and Medicine Taniguchi N, Endo T, Hart GW, Seeberger PH, Wong CH. Springer Japan, 699-705 (1568頁) 2015. |
| 35 | 美田敏宏. 特集未来への投資マラリア撲滅へ「薬剤耐性マラリア拡大の解明と対策」． 国際人流. 入管協会 340. 12-6, 223-5. 2015. |
| 36 | 山本典生. 今後出現が予想される新型インフルエンザウイルスは？ 内科 南江堂116(6), 1087-1090（362頁） 2015. |
| 37 | 鈴木香, 長岡功. Cathelicidinファミリーの抗菌ペプチドLL-37によるエンドトキシン除去作用. エンドトキシン・自然免疫研究18 -自然免疫における生体防御ペプチドの多様性. 長岡功,谷徹, 横地高志 編集, 医学図書出版, 東京, 1-6（100頁） 2015. |
| 38 | 胡忠双, 村上泰介, 鈴木香, 田村弘志, 長岡功. ピロトーシスに対する抗菌ペプチドLL-37の作用. エンドトキシン・自然免疫研究18 –自然免疫における生体防御ペプチドの多様性. 長岡功,谷徹, 横地高志 編集, 医学図書出版, 東京, 86-88（100頁） 2015. |
| 39 | 多田浩之, 松下健二, 松山考司, 長岡功, 高田春比古. Porphyromonas gingivalisジンジパインによるヒト歯肉上皮細胞のIL-33誘導を介したCAP18/LL-37ダウンレギュレーション機構. エンドトキシン・自然免疫研究18 –自然免疫における生体防御ペプチドの多様性. 長岡功,谷徹, 横地高志 編集, 医学図書出版, 東京, 93-97（100頁） 2015. |
| 40 | 森田芙路子, 上原由紀. 予防抗微生物薬 血液腫瘍領域の感染症 原田壮平編, 最新医学社 175-186 （243頁） 2015. |
| 41 | 美田敏宏. 旅行者下痢症とその対策. 改訂版アジア旅行者のための感染症対策．改訂第1版. 連合出版社．29-57. (223頁) 2015. |
| 42 | 奈良武司. トリパノソーマ症． 別冊骨格筋症候群（第2版）、上巻 日本臨牀、日本臨牀社、大阪、276-280（467頁） 2015. |
| 43 | 美田敏宏． 肺寄生虫症. EBMを活かす呼吸器診療. 高橋和久, 児玉裕三. メジカルビュー社 223-5 (541頁) 2015. |
特許
| 1 | 特許出願人：学校法人順天堂、生化学工業株式会社 発明者：長岡 功、村上泰介、蓬田 伸、田村弘志 発明の名称：アナンダミド生成抑制 特許出願日：2005年6月16日 特許出願番号：特願2005-176312 |
| 2 | 特許出願人：学校法人順天堂、生化学工業株式会社 発明者：長岡 功、平田陸正、田村弘志 発明の名称：アポトーシス抑制剤 特許出願日：2005年11月24日 特許出願番号：特願2005-339395 |
| 3 | 特許出願人： 学校法人順天堂、生化学工業株式会社 発明者 ： 長岡功、奥田大樹、蓬田 伸、田村弘志 発明の名称 ： 抗菌ペプチド 特許出願日 ：2005 年7 月5 日 |
| 4 | 特許出願人：公益財団法人微生物化学研究会、学校法人順天堂 発明者 ： 五十嵐雅之、平松啓一 発明の名称 ： 病原性細菌用抗菌剤、及びその用途 特許出願日 ：2011年08月24日 特許出願番号：特願2011-182657 |
| 5 | 特許出願人：学校法人順天堂 発明者 ： 山本典生 発明の名称 ： 抗インフルエンザウイルス剤 特許出願日 ：2012年08月10日 特許出願番号：特願2012-178250 |
| 6 | 特許出願人：学校法人順天堂 発明者 ： 平松啓一、森本ゆふ、馬場理 発明の名称 ： 抗菌剤 特許出願日 ：2013年11月12日 特許出願番号：特願2013-233957 |
| 7 | 特許出願人：学校法人順天堂、デンカ生研株式会社 発明者 ： 大石 金成、馬場理、平松啓一、中臣康雄. 発明の名称 ： 毒素検出方法 特許出願日 ：2013年03月21日 特許出願番号：特願2012-265453 |
| 8 | 特許出願人：公益財団法人ヒューマンサイエンス振興財団 発明者 ： 山本典生、浜本いつき、田代眞人 発明の名称 ： 細胞培養組成物、インフルエンザウイルスの生産方法、及び、インフルエンザウイルス 特許出願日 ：2013年03月22日 特許出願番号：特願2013-060692 |
| 9 | 特許出願人：学校法人順天堂、学校法人早稲田大学、清水建設株式会社 発明者 ： 堀賢、森本正一、田辺新一、町田晃一、杉山靖尚、山口一、辻裕次 発明の名称 ： 空調システム 特許出願日 ：2013年05月10日 特許出願番号：特願2013-100533 |
| 10 | 特許出願人：全薬工業株式会社、学校法人順天堂 発明者 ： 大澤弘宜、榎並淳平、平松啓一 発明の名称 ： 抗ブドウ球菌抗体、その製造方法並びにその使用 特許出願日 ：2014年3月11日 特許出願番号：特願2013049268 |
| 11 | 特許出願人：学校法人順天堂、国立研究開発法人国立精神・神経医療研究センター、国立大学法 人東京大学、学校法人麻布獣医学園 発明者：三宅幸子, 山村隆, 服部正平, 森田英利 自己免疫疾患の診断方法、自己免疫疾患の診断用バイオマーカー、及び自己免疫疾患の予防又は治療剤 特許出願日：2015年8月27日 特願2015-167839 |
| 12 | 特許出願人：国立大学法人千葉大学、学校法人順天堂 発明者：柳田浩志、星野忠次、山本典生 インフルエンザウイルス感染症の予防および／または治療剤 特許公開日：2015年6月26日 特許5765650号 |