Twitter
学校法人順天堂@juntendo1838
スポーツ健康科学部@juntendo_sakura
医療看護学部@juntendo_nurse
練馬病院@juntendo_nerima
LINE
学校法人順天堂@juntendo
スポーツ健康科学部@juntendo.sakura
Instagram
スポーツ健康科学部juntendo_sakura
研究活動Research Activities

感染制御科学研究センター

研究業績データ

主な研究業績(2017年)

1Singh M, Matsuo M, Sasaki T, Morimoto Y, Hishinuma T, Hiramatsu K. 
In Vitro Tolerance of A Drug-Naïve Staphylococcus aureus FDA209P towards Vancomycin. 
Antimicrob Agents Chemother. 24;61(2). 2017.
2Kikuchi K, Matsuda M, Iguchi S, Mizutani T, Hiramatsu 2, Tega-Ishii M, Sansaka K, Negishi K, Shimada K, Umemura J, Notake S, Yanagisawa H, Takahashi H, Yabusaki R, Araoka H, Yoneyama A.
Potential Impact of Rapid Blood Culture Testing for Gram-Positive Bacteremia in Japan with the Verigene Gram-Positive Blood Culture Test.
Can J Infect Dis Med Microbiol. :4896791. 2017.
3Tan XE, Neoh HM, Looi ML, Chin SF, Cui L, Hiramatsu K, Hussin S, Jamal R.
Activated ADI pathway: the initiator of intermediate vancomycin resistance in Staphylococcus aureus.
Can J Microbiol. 63(3):260-264. 2017.
4Ishikawa D, Sasaki T, Osada T, Kuwahara-Arai K, Haga K, Shibuya T, Hiramatsu K, Watanabe S. 
Changes in Intestinal Microbiota Following Combination Therapy with Fecal Microbial Transplantation and Antibiotics for Ulcerative Colitis. 
Inflammatory Bowel Diseases. 23(1):116-125. 2017.
5Sugiyama H, Yoshida I, Ueki M, Tanabe K, Manaka A, Hiramatsu K.
In vitro antibacterial activity of α-methoxyimino acylide derivatives against macrolide-resistant pathogens and mutation analysis in 23S rRNA.
J Antibiot (Tokyo). 70(3):264-271. 2017.
6Miyoshi N, Isogai M, Hiramatsu K, Sasaki T.
Activity of tick antimicrobial peptide from Ixodes persulcatus (persulcatusin) against cell membranes of drug-resistant Staphylococcus aureus.
J Antibiot. 70(2):142-146. 2017.
7Tanaka Y, Sato Y, Sasaki T.
Feline coronavirus replication is affected by both cyclophilin A and cyclophilin B.
J Gen Virol. 98(2):190-200. 2017.
8Balikagala B, Mita T, Ikeda M, Sakurai M, Yatsushiro S, Takahashi N, Tachibana SI, Auma M, Ntege EH, Ito D, Takashima E, Palacpac NM, Egwang TG, Onen JO, Kataoka M, Kimura E, Horii T, Tsuboi T.
Absence of in vivo selection for K13 mutations after artemether-lumefantrine treatment in Uganda.
Malar J. 16(1):23. 2017.
9Nakaminami H, Ito T, Han X, Ito A, Matsuo M, Uehara Y, Baba T, Hiramatsu K, Noguchi N.
First report of sasX-positive methicillin-resistant Staphylococcus aureus in Japan.
FEMS Microbiol Lett.  1;364(16). 2017
10Raulinaitis V, Tossavainen H, Aitio O, Juuti JT, Hiramatsu K, Kontinen V, Permi P. 
Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family. 
Sci Rep. 20;7(1):6020. 2017

主な研究業績(2016年)

1Mita T, Culleton R, Takahashi N, Nakamura M, Tsukahara T, Hunja CW, Win ZZ, Htike WW, Marma AS, Dysoley L, Ndounga M, Dzodzomenyo M, Akhwale WS, Kobayashi J, Uemura H, Kaneko A, Hombhanje F, Ferreira MU, Bjorkman A, Endo H, Ohashi J.
Little Polymorphism at the K13 Propeller Locus in Worldwide Plasmodium falciparum Populations Prior to the Introduction of Artemisinin Combination Therapies.
Antimicrob Agents Chemother. 2016 60(6):3340-7.
2Katayama Y, Sekine M, Hishinuma T, Aiba Y, Hiramatsu K.
Complete reconstitution of the VISA phenotype of Mu50 in Vancomycin-Susceptible Staphylococcus aureus.
Antimicrob Agents Chemother. 2016 60(6).3730-3743.
3Mita T, Tachibana S, Hashimoto M, Hirai M.
Plasmodium falciparum kelch 13: a potential molecular marker for tackling artemisinin-resistant malaria parasites.
Expert Rev Anti Infect Ther. 2016 14(1):125-35.
4Hishinuma T, Katayama Y, Matsuo M, Sasaki T, Hiramatsu K.
Complete Genome Sequence of Vancomycin-Intermediate Staphylococcus aureus Strain MI (HIP5827).
Genome Announc. 2016 17;4(2) pii: e00123-16.
5Murakami T, Hu Z, Tamura H, Nagaoka I.
Release mechanism of high mobility group nucleosome binding protein 1 from lipopolysaccharide-stimulated macrophages.
Mol Med Rep 2016 13: 3115-3120.
6Hashimoto M, Nara T, Mita T, Mikoshiba K.
Morpholino antisense oligo inhibits trans-splicing of pre-inositol 1,4,5-trisphosphate receptor mRNA of Trypanosoma cruzi and suppresses parasite growth and infectivity.
Parasitol Int. 2016 65:175-179.
7Takamiya S, Mita T.
Large-scale purification of active liquid-cultured Caenorhabditis elegans using a modified Baermann apparatus.
Parasitol Int. 2016 65(5 Pt B):580-583.
8Iguchi S, Mizutani T, Hiramatsu K, Kikuchi K.
Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination.
PLoS One. 2016 16;11(5):e0155512.
9Yatsushiro S, Yamamoto T, Yamamura S, Abe K, Obana E, Nogami T, Hayashi T, Sesei T, Oka H, Okello-Onen J, Odongo-Aginya EI, Alai MA, Olia A, Anywar D, Sakurai M, Palacpac NM, Mita T, Horii T, Baba Y, Kataoka M.
Application of a cell microarray chip system for accurate, highly sensitive, and rapid diagnosis for malaria in Uganda.
Scientific reports. 2016 6:30136.
10Honma H, Niikura M, Kobayashi F, Horii T, Mita T, Endo H, Hirai M.
Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase delta.
Scientific reports. 2016 6:36971.

英文原著(2015年)

1Matsuo M, Hishinuma T, Katayama Y, Hiramatsu K.
A mutaion of RNA polymerase β' subunit (RpoC) converts heterogeneously vancomycin intermediate S. aureus (hVISA) into 'slow-VISA' (sVISA).
Antimicrob Agents Chemother. 59(7):4215-25. 2015.
2Yoshihara N, Ueno T, Takagi A, Oliva Trejo JA, Haruna K, Suga Y, Komatsu M, Tanaka K, Ikeda S.
The significant role of autophagy in the granular layer in normal skin differentiation and hair growth.
Arch Dermatol Res. 307(2):159-69. 2015.
3Takenaka S-I, Kaieda S, Kawayama T, Matsuoka M, Kaku Y, Kinoshita T, Sakazaki Y, Okamoto M, Tominaga M, Kanesaki K, Chiba A, Miyake S, Ida H, Hoshino T. IL-38:
A new factor in rheumatoid arthritis.
Biochem Biophys Rep. 4:386-391 2015.
4Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S.
ICOS promotes group 2 innate lymphoid cell activation in lungs.
Biochem Biophys Res Commun. 463(4):739-45 2015.
5Hashimoto M, Nara T, Enomoto M, Kurebayashi N, Yoshida M, Sakurai T, Mita T, Mikoshiba K.
A dominant negative form of inositol 1,4,5-trisphosphate receptor induces metacyclogenesis and increases mitochondrial density in Trypanosoma cruzi.
Biochem Biophys Res Commun. 466:475-480. 2015.
6Ekyalongo RC, Nakayama H, Kina K, Kaga N, Iwabuchi K.
Organization and functions of glycolipid-enriched microdomains in phagocytes.
Biochim Biophys Acta, 1851:90-7. 2015.
7Fudo S*, Yamamoto N*, Nukaga M, Odagiri T, Tashiro M, Neya S, Hoshino T (*These authors contributed equally to this work).
Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase.
Bioorg Med Chem. 1;23(17):5466-75. 2015.
8Tanaka Y, Sasaki T, Matsuda R, Uematsu Y, Yamaguchi T.
Molecular epidemiological study of feline coronavirus strains in Japan using RT-PCR targeting nsp14 gene.
BMC Veterinary Research 11:57. 2015.
9Sugimura T*, Takahashi H*, Jounai K, Ohshio K, Kanayama M, Tazumi K, Tanihata Y, Miura Y, Fujiwara D, Yamamoto N*(*These authors contributed equally to this work).
Effects of oral intake of pDC-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus.
Br J Nutr. 14;114(5):727-33. 2015.
10Croxford JL, Miyake S.
Immunoregulation of multiple sclerosis by gut environmental factors.
Clin Exp Neuroimmunol. 6(4):362–369 2015.
11Dong H, Franklin NA, Ritchea SB, Yagita H, Glennie MJ, Bullock TN.
CD70 and IFN-1 selectively induce Eomesdermin or T-bet and synergize to promote CD8+ T-cell responses.
Eur J Immunol. 45: 3289-3301 2015.
12Iwabuchi K.
Involvement of glycosphingolipid-enriched lipid rafts in inflammatory responses.
Front Biosci (Landmark Ed). 20:325-34, 2015 2015.
13Tsukahara T, Ogura S, Sugahara T, Sekihara M, Furusawa T, Kondo N, Mita T, Endo H, Hombhanje F.
The Choice of Healthcare Providers for Febrile Children after Introducing Non-professional Health Workers in a Malaria Endemic Area in Papua New Guinea.
Front Public Health. 2015;3:275. 2015.
14Singh M, Sasaki T, Matsuo M, Morimoto Y, Aiba Y, Hiramatsu K.
Complete Genome Sequence of a Drug-naive Classical Staphylococcus aureus Strain FDA209P.
Genome Announc. 12;3(6). 2015.
15Sasaki T, Tsubakishita S, Kuwahara-Arai K, Mastuo M, Lu YJ, Tanaka Y, Hiramatsu K.
Complete Genome Sequence of a Methicillin-Resistant Staphylococcus schleiferi Strain TSCC54, of Canine Origin.
Genome Announc. 29;3(5). 2015.
16Iwabuchi K, Masuda H, Kaga N, Nakayama H, Matsumoto R, Iwahara C, Yoshizaki F, Tamaki Y, Kobayashi T, Hayakawa T, Ishii K, Yanagida M, Ogawa H, Takamori K.
Properties and Functions of Lactosylceramide from Mouse Neutrophils.
Glycobiology. 25: 655-68, 2015 2015.
17Jesus M, Rodriguez AE, Yagita H, Ostroff GR, Mantis NJ.
Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer’s patches.
Immunol Lett. 168: 64-72. 2015.
18Tsutsui-Takeuchi M, Ushio H, Fukuda M, Yamada T, Niyonsaba F, Okumura K, Ogawa H, Ikeda S.
Roles of retinoic acid-inducible gene-I-like receptors (RLRs), Toll-like receptor (TLR) 3 and 2'-5' oligoadenylate synthetase as viral recognition receptors on human mast cells in response to viral infection.
Immunol Res. 2015 61(3):240-9. 2015.
19Tajiri H, Nishi J, Ushijima K, Shimizu T, Ishige T, Shimizu M, Tanaka H, Brooks S.
A role for fosfomycin treatment in children for prevention of haemolytic-uraemic syndrome accompanying Shiga toxin-producing Escherichia coli infection.
Int J Antimicrob Agents 46:586-9. 2015.
20Morimoto Y, Baba T, Sasaki T, Hiramatsu K.
Apigenin as an Anti-Quinolone-Resistance Antibiotic.
Int J Antimicrob Agents. 46(6):666-73. 2015.
21Murate M, Abe M, Kasahara K, Iwabuchi K, Umeda M, Kobayashi T.
Transbilayer lipid distribution in nano scale.
J Cell Sci. 128:1627-3820. 2015.
22Smithrithee R, Niyonsaba F, Kiatsurayanon C, Ushio H, Ikeda S, Okumura K, Ogawa H.
Human β-defensin-3 increases the expression of interleukin-37 through CCR6 in human keratinocytes.
J Dermatol Sci. 77(1):46-53. 2015.
23Yamazaki S, Nakano N, Honjo A, Hara M, Maeda K, Nishiyama C, Kitaura J, Ohtsuka Y, Okumura K, Ogawa H, Shimizu T.
The Transcription Factor Ehf Is Involved in TGF-beta-Induced Suppression of Fc epsilon RI and c-Kit Expression and Fc epsilon RI-Mediated Activation in Mast Cells.
J Immunol 195:3427-35. 2015.
24Uehara Y, Ito T, Ogawa Y, Hirotaki S, Shoji T, Tame T, Horikoshi Y, Hiramatsu K.
Molecular epidemiologic study of community-associated methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin gene among family members in Japan.
J Infect Chemother 21: 700-702. 2015.
25Chiricozzi E, Ciampa MG, Brasile G, Compostella F, Prinetti A, Nakayama H, Ekyalongo RC, Iwabuchi K, Sonnino S, Mauri L.
Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells.
J Lipid Res, 56:129-41. 2015.
26Nara T.
Current situation of Chagas disease in non-endemic countries.
Juntendo Med J 61: 389-395. 2015.
27Yamamoto N.
An overview of Ebola virus disease: History, pathogenesis, and treatment.
Juntendo Medical Journal, 61(4): 350-472. 2015.
28Mita T.
Current Research Topics in Tropical Diseases; Towards Successful Control and Elimination.
Juntendo Medical Journal. 61(4):358-9. 2015.
29Hirai M, Mita T.
Challenging Malaria Control.
Juntendo Medical Journal. 61(4):370-7. 2015.
30Iwabuchi K, Nakayama H, Oizumi A, Suga Y, Ogawa H, Takamori K.
Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans.
Mediators Inflamm. 2015:120748. 2015.
31Matsunaga N, Hisata K, Shimizu T.
An investigation into the vancomycin concentration in the cerebrospinal fluid due to vancomycin intraventricular administration in newborns: a study of 13 cases.
Medicine 94:e922. 2015.
32Ohsawa H, Baba T, Enami J, Hiramatsu K.
Successful selection of an infection-protective anti-Staphylococcus aureus monoclonal antibody and its protective activity in murine infection models.
Microbiol Immunol. 59:183-92 2015.
33Mita T, Jombart T.
Patterns and dynamics of genetic diversity in Plasmodium falciparum: what past human migrations tell us about malaria.
Parasitol Int. 64(3):238-43. 2015.
34Tanabe K, Zollner G, Vaughan JA, Sattabongkot J, Khuntirat B, Honma H, Mita T, Tsuboi T, Coleman R.
Plasmodium falciparum: genetic diversity and complexity of infections in an isolated village in western Thailand.
Parasitol Int. 64(3):260-6. 2015.
35Murai K, Culleton R, Hisaoka T, Endo H, Mita T.
Global distribution of polymorphisms associated with delayed Plasmodium falciparum parasite clearance following artemisinin treatment: genotyping of archive blood samples.
Parasitol Int. 64(3):267-73. 2015.
36Suzuki M, Saito N, Naritaka N, Nakano S, Minowa K, Honda Y, Ohtsuka Y, Yamataka A, Shimizu T.
Scoring system for the prediction of severe acute pancreatitis in children.
Pediatr Int 57:113-8. 2015.
37Hashimoto M, Morales J, Uemura H, Mikoshiba K, Nara T.
A novel method for inducing amastigote-to-trypomastigote transformation in vitro in Trypanosoma cruzi reveals the importance of inositol 1,4,5-trisphosphate receptor.
PLoS One. 10:e0135726. 2015.
38Hasegawa T, Sakamoto A, Wada A, Fukai T, Iida H, Ikeda S.
Keratinocyte progenitor cells reside in human subcutaneous adipose tissue.
PLoS One. 10(2):e0118402. 2015.
39Miyake S, Kim S, Suda W, Oshima K, Nakamura M, Matsuoka T, Chihara N, Tomita A, Sato W, Kim S, Morita H, Hattori M, Yamamura T.
Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters.
PLoS One. 10(9):e0137429 2015.
40Ishii K, Tabuchi F, Matsuo M, Tatsuno K, Sato T, Okazaki M, Hamamoto H, Matsumoto Y, Kaito C, Aoyagi T, Hiramatsu K, Kaku M, Moriya K, Sekimizu K.
Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro mutagenesis.
Sci Rep. 25;5:17092. 2015.
41Hasegawa T, Ikeda S.
Adipose-derived stromal/stem cells as potential source of skin regeneration.
Stem Cell Transl Investig. 2:e787 2015.
42Tanaka Y, Sato Y, Takahashi D, Matsumoto H, Sasaki T.
Treatment of a case of feline infectious peritonitis with cyclosporin A.
Vet Rec Case Rep. 3:e000134. 2015.
43Hiramatsu K, Morimoto Y.
Farewell Lecture: Future Chemotherapy Preventing Emergence of Multi-Antibiotic Resistance.
Juntendo Med J. 61(3) 249-256. 2015.

英文原著(2014年)

1Hiramatsu K, Katayama Y, Matsuo M, Aiba Y, Saito M, Hishinuma T, Iwamoto A.
Vancomycin-intermediate resistance in Staphylococcus aureus.
J Glob Antimicrob Resist. 2014 Dec;2(4) :213–224
2Hiramatsu K, Katayama Y, Matsuo M, Sasaki T, Morimoto Y, Sekiguchi A, Baba T.
Multi-Drug-Resistant Staphylococcus aureus and Future Chemotherapy.
J Infect Chemother. 2014 Oct;20(10):593-601.
3Honma H, Hirai M, Nakamura S, Hakimi H, Kawazu S, Palacpac NM, Hisaeda H, Matsuoka H, Kawai S, Endo H, Yasunaga T, Ohashi J, Mita T, Horii T, Furusawa M, Tanabe K.
Generation of rodent malaria parasites with a high mutation rate by destructing proofreading activity of DNA polymerase δ.
DNA Res. 2014 Aug;21(4):439-46.
4Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I.
Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism.
PLoS One. 2014 Jan 16;9(1):e85765.
5Ito T, Kuwahara-Arai K, Katayama Y, Uehara Y, Han X, Kondo Y, Hiramatsu K.
Staphylococcal Cassette Chromosome mec (SCCmec) analysis of MRSA.
Methods Mol Biol. 2014;1085:131-48.
6Mita T, Ohashi J, Venkatesan M, Marma AS, Nakamura M, Plowe CV, Tanabe K.
Ordered accumulation of mutations conferring resistance to sulfadoxine-pyrimethamine in the Plasmodium falciparum parasite.
J Infect Dis. 2014 Jan 1;209(1):130-9.
7Nakao A, Ito T, Han X, Lu YJ, Hisata K, Tsujiwaki A, Matsunaga N, Komatsu M, Hiramatsu K, Shimizu T.
Intestinal carriage of methicillin-resistant Staphylococcus aureus in nasal MRSA carriers hospitalized in the neonatal intensive care unit.
Antimicrob Resist Infect Control. 2014 Apr;3:14.
8Saito M, Katayama Y, Hishinuma T, Iwamoto A, Aiba Y, Kuwahara-Arai K, Cui L, Matsuo M, Aritaka N, Hiramatsu K.
Slow VISA' (sVISA), a novel phenotype of vancomycin resistance, obtained in vitro from hVISA strain Mu3.
Antimicrob Agents Chemother. 2014 Sep;58(9):5024-35.
9Takai T, Chen X, Xie Y, Vu AT, Le TA, Kinoshita H, Kawasaki J, Kamijo S, Hara M, Ushio H, Baba T, Hiramatsu K, Ikeda S, Ogawa H, Okumura K.
TSLP expression induced via Toll-like receptor pathways in human keratinocytes.
Methods Enzymol. 2014;535:371-87.

英文原著(2013年)

1Aiba Y, Katayama Y, Hishinuma T, Murakami-Kuroda H, Cui L, Hiramatsu K.
Mutation of RNA polymerase β-subunit gene promotes heterogeneous-to-homogeneous conversion of β-lactam resistance in methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2013 Oct;57(10):4861-71.
2Hiramatsu K, Ito T, Tsubakishita S, Sasaki T, Takeuchi F, Morimoto Y, Katayama Y, Matsuo M, Kuwahara-Arai K, Hishinuma T, Baba T.
Genomic Basis for Methicillin Resistance in Staphylococcus aureus1 Infect Chemother.
2013 Jun;45(2):117-36. Review.
3Hunja CW, Unger H, Ferreira PE, Lumsden R, Morris S, Aman R, Alexander C, Mita T, Culleton R.
Travellers as sentinels: Assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in Plasmodium falciparum using malaria cases imported into Scotland.
Int J Parasitol. 2013 Oct;43(11):885-9.
4Kaito C, Saito Y, Ikuo M, Omae Y, Mao H, Nagano G, Fujiyuki T, Numata S, Han X, Obata K, Hasegawa S, Yamaguchi H, Inokuchi K, Ito T, Hiramatsu K, Sekimizu K.
Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence.
PLoS Pathog. 2013;9(4):e1003269.
5Khattak AA, Venkatesan M, Jacob CG, Artimovich EM, Nadeem MF, Nighat F, Hombhanje F, Mita T, Malik SA, Plowe CV.
A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan.
Malar J. 2013 Aug 29;12:300.
6Lulitanond A, Ito T, Li S, Han X, Ma XX, Engchanil C, Chanawong A, Wilailuckana C, Jiwakanon N, Hiramatsu K.
ST9 MRSA strains carrying a variant of type IX SCCmec identified in the Thai community.
BMC Infect Dis. 2013 May;13:214.
7Matsuo M, Cui L, Kim J, Hiramatsu K.
Comprehensive identification of mutations responsible for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA)-to-VISA conversion in laboratory-generated VISA strains derived from hVISA clinical strain Mu3.
Antimicrob Agents Chemother. 2013 Dec;57(12):5843-53.
8Notake S, Matsuda M, Tamai K, Yanagisawa H, Hiramatsu K, Kikuchi K.
Detection of IMP metallo-β-lactamase in carbapenem-non-susceptible Enterobacteriaceae and glucose non-fermenting Gram-negative rods by immunochromatography assay.
J Clin Microbiol. 2013 Jun;51(6):1762-8.
9Ohkushi D, Uehara Y, Iwamoto A, Misawa S, Kondo S, Shimizu K, Hori S, Hiramatsu K.
An effective active surveillance method for controlling nosocomial MRSA transmission in a Japanese hospital.
J Infect Chemother. 2013 Oct;19(5):871-5.
10Tanabe K, Jombart T, Horibe S, Palacpac NM, Honma H, Tachibana S, Nakamura M, Horii T, Kishino H, Mita T.
Plasmodium falciparum mitochondrial genetic diversity exhibits isolation-by-distance patterns supporting a sub-Saharan African origin.
Mitochondrion. 2013 Nov;13(6):630-6.
11Tomoyasu T, Imaki H, Masuda S, Okamoto A, Kim H, Waite RD, Whiley RA, Kikuchi K, Hiramatsu K, Tabata A, Nagamune H.
LacR mutations are frequently observed in Streptococcus intermedius and are responsible for increased intermedilysin production and virulence.
Infect Immun. 2013 Sep;81(9):3276-86.
12Uehara Y, Kuwahara-Arai K, Hori S, Kikuchi K, Yanai M, Hiramatsu K.
Investigation of nasal meticillin-resistant Staphylococcus aureus carriage in a haemodialysis clinic in Japan.
J Hosp Infect. 2013 May;84(1):81-4.
13Zhang M, Ito T, Li S, Misawa S, Kondo S, Miida T, Ohsaka A, Hiramatsu K.
Analysis of Staphylococcal Cassette Chromosome mec in BD GeneOhm™ MRSA Assay negative strains.
Antimicrob Agents Chemother. 2013 Jun;57(6):2890-1.

英文原著(2012年)

1Hashimoto H, Morales J, Fukai Y, Suzuki S, Takamiya S, Tsubouchi A, Inoue S, Inoue M, Kita K, Harada S, Tanaka A, Aoki T, Nara T.
Critical importance of the de novo pyrimidine biosynthesis pathway for Trypanosoma cruzi growth in the mammalian host cell cytoplasm.
Biochem Biophys Res Commun. Jan 20;417(3):1002-6. 2012
2Kayama H, Ueda Y, Sawa Y, Jeon SG, Ma JS, Okumura R, Kubo A, Ishii M, Okazaki T, Murakami M, Yamamoto M, Yagita H, Takeda K.
Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis.
Proc Natl Acad Sci U S A. Mar 27;109(13):5010-5. 2012
3Kitamura N, Yokoyama H, Yashiro T, Nakano N, Nishiyama M, Kanada S, Fukai T, Hara M, Ikeda S, Ogawa H, Okumura K, Nishiyama C.
Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells.
J Allergy Clin Immunol. Mar;129(3):814-824.e6. 2012
4Miyano G, Takahashi T, Takahashi T, Lane GJ, Kato Y, Okazaki T, Yamataka A.
An unusual foreign body in an inguinal hernia sac: case report and literature review.
Afr J Paediatr Surg. Jan-Apr;9(1):66-7. 2012
5Nakamura H, Koga H, Wada M, Miyano G, Dizon R, Kato Y, Lane GJ, Okazaki T, Yamataka A.
Reappraising the portoenterostomy procedure according to sound physiologic/anatomic principles enhances postoperative jaundice clearance in biliary atresia.
Pediatr Surg Int. Feb;28(2):205-9. 2012
6Nakamura H, Okazaki T, Koga H, Lane GJ, Yamataka A.
Congenital brachioesophagus with secondary intrathoracic stomach associated with rachischisis described as "serpentine-like syndrome": a case report and literature review.
Pediatr Surg Int. Jan;28(1):63-6. 2012
7Nara T, Hashimoto M, Hirawake H, Liao CW, Fukai Y, Suzuki S, Tsubouchi A, Morales J, Takamiya S, Fujimura T, Taka H, Mineki R, Fan CK, Inaoka K, Inoue M, Tanaka A, Harada S, Kita K, Aoki T.
Molecular interaction of the first 3 enzymes of the de novo pyrimidine biosynthetic pathway of Trypanosoma cruzi.
Biochem Biophys Res Commun. Feb 3;418(1):140-3. 2012
8Nishina T, Komazawa-Sakon S, Yanaka S, Piao X, Zheng DM, Piao JH, Kojima Y, Yamashina S, Sano E, Putoczki T, Doi T, Ueno T, Ezaki J, Ushio H, Ernst M, Tsumoto K, Okumura K, Nakano H.
Interleukin-11 links oxidative stress and compensatory proliferation.
Sci Signal. Jan17;5(207):ra5. 2012
9Nishioka J, Iwahara C, Kawasaki M, Yoshizaki F, Nakayama H, Takamori K, Ogawa H, Iwabuchi K.
Di-(2-ethylhexyl) phthalate induces production of inflammatory molecules in human macrophages.
Inflamm Res. Jan;61(1):69-78. 2012
10Ochi T, Okazaki T, Miyano G, Lane GJ, Yamataka A.
A comparison of clinical protocols for assessing postoperative fecal continence in anorectal malformation.
Pediatr Surg Int. Jan;28(1):1-4. 2012
11Ohtsuka Y, Ikegami T, Izumi H, Namura M, Ikeda T, Ikuse T, Baba Y, Kudo T, Suzuki R, Shimizu T.
Effects of Bifidobacterium breve on inflammatory gene expression in neonatal and weaning rat intestine.
Pediatr Res. Jan;71(1):46-53. 2012
12Oka F, Naito T, Oike M, Imai R, Saita M, Inui A, Mitsuhashi K, Isonuma H, Shimbo T.
Correlation between HIV disease and lipid metabolism in antiretroviral-naïve HIV-infected patients in Japan.
J Infect Chemother. Feb;18(1):17-21. 2012
13Okumura A, Tsuji T, Kubota T, Ando N, Kobayashi S, Kato T, Natsume J, Hayakawa F, Shimizu T.
Acute encephalopathy with 2009 pandemic flu: Comparison with seasonal flu.
Brain Dev. Jan;34(1):13-9. 2012
14Seo S, Takahashi T, Marusasa T, Kusafuka J, Koga H, Halibieke A, Lane GJ, Okazaki T, Yamataka A.
Management of inguinal hernia in children can be enhanced by closer follow-up by consultant pediatric surgeons.
Pediatr Surg Int. Jan;28(1):33-6. 2012
15Sugasawa Y, Yamaguchi K, Kumakura S, Murakami T, Suzuki K, Nagaoka I, Inada E.
Effects of sevoflurane and propofol on pulmonary inflammatory responses dusing lung resection.
J Anesth. Feb;26(1):62-9. 2012
16Yanagita H, Yamamoto N, Fuji H, Liu X, Ogata M, Yokota M, Takaku H, Hasegawa H, Odagiri T, Tashiro M, Hoshino T.
Mechanism of Drug Resistance of Hemagglutinin of Influenza Virus and Potent Scaffolds Inhibiting Its Function.
ACS Chem Biol. 2012 Mar 16;7(3):552-62. 2012

英文原著(2011年)

1Aihara M, Hasegawa T, Okuyama Y, Hiruma M, Ikeda S.
Langerhans cell histiocytosis treated with narrow-band ultraviolet B.
J Dermatol. Feb;38(2):151-4. 2011
2Arii R, Koga H, Arakawa A, Miyahara K, Lane GJ, Okazaki T, Urao M, Yamataka A.
How valuable is ductal plate malformation as a predictor of clinical course in postoperative biliary atresia patients?
Pediatr Surg Int. Mar;27(3):275-7. 2011
3Asaoka D, Nagahara A, Oguro M, Mori H, Nakae K, Izumi Y, Osada T, Hojo M, Otaka M, Watanabe S.
Establishment of a reflux esophago-laryngitis model in rats.
Dig Dis Sci.56,1299-1308, 2011
4Aung G, Niyonsaba F, Ushio H, Hoq MI, Ikeda S, Ogawa H, Okumura K.
A neuroendocrine antimicrobial peptide, catestatin, stimulates interleukin-8 production from human keratinocytes via activation of mitogen-activated protein kinases.
J Dermatol Sci. 2011 Feb;61(2):142-4. 2011
5Aung G, Niyonsaba F, Ushio H, Ikeda S, Okumura K, Ogawa H.
Elafin and secretory leukocyte protease inhibitor stimulate the production of cytokines and chemokines by human keratinocytes via MAPK/ERK and NF-κB activation.
J Dermatol Sci. 2011 Aug;63(2):128-31. 2011
6Aung G, Niyonsaba F, Ushio H, Kajiwara N, Saito H, Ikeda S, Ogawa H, Okumura K.
Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. Immunology.
2011 Apr;132(4):527-39. 2011
7Beppu K, Osada T, Inoue K, Matsumoto K, Shibuya T, Sakamoto N, Kawabe M, Nagahara A, Ogihara T, Watanabe S.
Intestinal involvement in Wegener's granulomatosis diagnosed and followed up by double balloon enteroscopy.
Intern Med. 50(3):219-22, 2011
8Beppu K, Osada T, Nagahara A, Matsumoto K, Shibuya T, Sakamoto N, Otaka M, Terai T, Ogihara T, Watanabe S.
Relationship between endoscopic finding and clinical severity in ischemic colitis.
Intern Med. 50(20):2263-7. 2011
9Charbonney E, Speight P, Masszi A, Nakano H, Kapus A.
beta-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition.
Mol Biol Cell. Dec;22(23):4472-85. 2011
10Ding Q, Yeung M, Camirand G, Zeng Q, Akiba H, Yagita H, Chalasani G, Sayegh MH, Najafian N, Rothstein DM.
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice.
J Clin Invest. Sep;121(9):3645-56. 2011
11Donaldoson DS, Kobayashi A, Ohno H, Yagita H, Williams IR, Mabbott NA.
M cell-depletion blocks oral prion disease pathogenesis.
Mucosal Immunol. Mar;5(2):216-25. 2012
12Fujii T, Hou R, Sato-Hayashizaki A, Obata M, Ohtsuji M, Ikeda K, Mitsui K, Kodera Y, Shirai T, Hirose S, Nishimura H.
Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: Implication of epistatic effects of Fcgr2b and Slam family genes.
Eur J Immunol. Aug;41(8):2333-40. 2011
13Funakushi N, Yamaguchi T, Jiang J, Imamura S, Kuhara T, Suto H, Ueki R, Kase Y, Kobayashi H, Ogawa H, Ikeda S.
Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.
Arch Dermatol Res. Nov;303(9):659-67. 2011
14Goto S, Okazaki T, Koga H, Miyano G, Arakawa A, Yao T, Lane GJ, Yamataka A.
Ectopic pancreas presenting as a submucosal gastric tumor: case report and literature review.
Pediatr Surg Int. Jan;27(1):107-9. Review. 2011
15Higashiyama M, Ito T, Han X, Tanno A, Wada T, Funaoka Y, Yoshida Y, Mikita K, Ogawa T, Nishiyama J, Okusa Y, Kaku K, Hatada J, Hiramatsu K, Kawana A.
Trial to control an outbreak of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus at a boarding school in Japan.
Am J Infect Control. Dec;39(10):858-65. 2011
16Hirose K, Iwabuchi K, Shimada K, Kiyanagi T, Iwahara C, Nakayama H, Daida H.
Different responses to oxidized low-density lipoproteins in human polarized macrophages.
Lipids Health Dis. Jan 4;10:1. 2011
17Hirotaki S, Sasaki T, Kuwahara-Arai K, Hiramatsu K.
Rapid and accurate identification of human associated staphylococci by multiplex PCR.
J Clin Microbiol. Oct;49(10):3627-31. 2011
18Hirotsu M, Kikuchi K, Kusunoki T, Kase K, Ono N, Ikeda K.
Comparison of bacterial examinations between eosinophilic and neutrophilic chronic rhinosinusitis with nasal polyps.
Acta Otolaryngol. Sep;131(9):997-1001. 2011
19Hiruma A, Ikeda S, Terui T, Ozawa M, Hashimoto T, Yasumoto S, Nakayama J, Kubota Y, Iijima M, Sueki H, Matsumoto Y, Kato M, Akasaka E, Ikoma N, Mabuchi T, Tamiya S, Matsuyama T, Ozawa A, Inoko H, Oka A.
A novel splicing variant of CADM2 as a protective transcript of psoriasis.
Biochem Biophys Res Commun. Sep 9;412(4):626-32. 2011
20Hisata K, Ito T, Matsunaga N, Komatsu M, Jin J, Li S, Watanabe S, Shimizu T, Hiramatsu K.
Dissemination of multiple MRSA clones among community-associated methicillin-resistant Staphylococcus aureus infections from Japanese children with impetigo.
J Infect Chemother. Oct;17(5):609-21. 2011
21Hojo M, Ohkusa T, Tomeoku H, Koido S, Asaoka D, Nagahara A, Watanabe S.
Corticotropin-releasing factor secretion from dendritic cells stimulated by commensal bacteria.
World J Gastroenterol. Sep 21;17(35):4017-22, 2011
22Hongou H, Fu K, Ueyama H, Takahashi T, Takeda T, Miyazaki A, Watanabe S.
Mallory-Weiss tear during gastric endoscopic submucosal dissection.
World J Gastrointest Endosc. Jul 16;3(7):151-3. 2011
23Hosoda H, Tamura H, Kida S, Nagaoka I.
Transcriptional regulation of mouse TREM-1 gene in RAW264.7 macrophage-like cells.
Life Sci. Jul 18;89(3-4):115-22. 2011
24Inage E, Saito M, Saito Y, Takata O, Fujimura J, Yamataka A, Shimizu T.
Contralateral pleural recurrence of adrenocortical carcinoma after surgical resection.
Pediatr Int. Aug;53(4):600-3. 2011
25Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M.
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
J Cell Biol 18,193,275-84. 2011
26Inami Y, Yamashina S, Izumi K, Ueno T, Tanida I, Ikejima K, Watanabe S.
Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression.
Biochem Biophys Res Commun. Sep 9;412(4):618-25. 2011
27Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S.
CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice.
J Hepatol. Jun;54(6):1195-204. 2011
28Itatsu T, Nagahara A, Hojo M, Miyazaki A, Murai T, Nakajima M, Watanabe S.
Use of selective serotonin reuptake inhibitors and upper gastrointestinal disease.
Intern Med. 50(7):713-7. 2011
29Kabir SM, Kikuchi K, Asakura M, Shiramaru S, Tsuruoka N, Goto A, Hinenoya A, Yamasaki S.
Evaluation of a cytolethal distending toxin (cdt) gene-based species-specific multiplex PCR assay for the identification of Campylobacter strains isolated from diarrheal patients in Japan.
Jpn J Infect Dis. 2011;64(1):19-27. 2011
30Kaga M, Sugita T, Nishikawa A, Wada Y, Hiruma M, Ikeda S.
Molecular analysis of the cutaneous Malassezia microbiota from the skin of patients with atopic dermatitis of different severities.
Mycoses. Jul;54(4):e24-8. 2011
31Kawasaki J, Ushio H, Kinoshita H, Fukai T, Niyonsaba F, Takai T, Ogawa H, Okumura K, Ikeda S.
Viral infection induces Thymic stromal lymphopoietin (TSLP) in human keratinocytes.
J Dermatol Sci. May;62(2):131-4. 2011
32Kina K, Masuda H, Nakayama H, Nagatsuka Y, Nabetani T, Hirabayashi Y, Takahashi Y, Shimada K, Daida H, Ogawa H, Takamori K, Iwabuchi K.
The novel neutrophil differentiation marker phosphatidylglucoside mediates neutrophil apoptosis.
J Immunol. May 1;186(9):5323-32. 2011
33Kiyanagi T, Iwabuchi K, Shimada K, Hirose K, Miyazaki T, Sumiyoshi K, Iwahara C, Nakayama H, Masuda H, Mokuno H, Sato S, Daida H.
Involvement of cholesterol-enriched microdomains in class A scavenger receptor-mediated responses in human macrophages. Atherosclerosis.
Mar;215(1):60-9. 2011
34Kodani T, Osada T, Terai T, Ohkusa T, Shibuya T, Sakamoto N, Beppu K, Kato J, Nagahara A, Watanabe H, Watanabe S.
Successful endoscopic mucosal resection of a solitary extramedullary plasmacytoma in the sigmoid colon. Endoscopy.
43 Suppl 2 UCTN:E298-9. 2011
35Koga H, Miyano G, Takahashi T, Shimotakahara A, Kato Y, Lane GJ, Okazaki T, Yamataka A.
Laparoscopic portoenterostomy for uncorrectable biliary atresia using Kasai's original technique.
J Laparoendosc Adv Surg Tech A. Apr;21(3):291-4. 2011
36Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K, Yagita H.
Importin beta1 Protein-mediated Nuclear Localization of Death Receptor 5 (DR5) Limits DR5/Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Cell Death of Human Tumor Cells.
J Biol Chem. Dec 16;286(50):43383-93. 2011
37Le TA, Takai T, Vu AT, Kinoshita H, Chen X, Ikeda S, Ogawa H, Okumura K.
Flagellin induces the expression of thymic stromal lymphopoietin in human keratinocytes via toll-like receptor 5.
Int Arch Allergy Immunol. Apr;155(1):31-7. 2011
38Li S, Skov RL, Han X, Larsen AR, Larsen J, Sørum M, Wulf M, Voss A, Hiramatsu K, Ito T.
Novel types of staphylococcal cassette chromosome mec elements identified in CC398 methicillin resistant Staphylococcus aureus strains.
Antimicrob Agents Chemother. Jun;55(6):3046-50. 2011
39Liao CW, Sukati H, Nara T, Tsubouchi A, Chou CM, Jian JY, Huang YC, Chang WS, Chiu WT, Huang YH, Fan CK.
Prevalence of Schistosoma haematobium Infection among Schoolchildren in Remote Areas Devoid of Sanitation in Northwestern Swaziland, Southern Africa.
Jpn J Infect Dis. 64:322-326. 2011
40Ma J, Usui Y, Takeda K, Harada N, Yagita H, Okumura K, Akiba H.
TIM-1 signaling in B cells regulates antibody production.
Biochem Biophys Res Commun. Mar 11;406(2):223-8. 2011
41Makiuchi T, Annoura T, Hashimoto M, Hashimoto T, Aoki T, Nara T.
Compartmentalization of a glycolytic enzyme in Diplonema, a non-kinetoplastid Euglenozoan.
Protist. 162(3):482-489. 2011
42Matsumoto K, Nagahara A, Sakamoto N, Suyama M, Konuma H, Morimoto T, Sagawa E, Ueyama H, Takahashi T, Beppu K, Shibuya T, Osada T, Yoshizawa T, Ogihara T, Watanabe S.
A new traction device for facilitating endoscopic submucosal dissection (ESD) for early gastric cancer: the "medical ring".
Endoscopy. 43 Suppl 2:E67-8. 2011
43Matsumoto K, Nagahara A, Terai T, Ueyama H, Ritsuno H, Mori H, Nakae K, Beppu K, Shibuya T, Sakamoto N, Osada T, Ogihara T, Yao T, Watanabe S.
Evaluation of new subclassification of type V(I) pit pattern for determining the depth and type of invasion of colorectal neoplasm.
J Gastroentor 46,1,31-38. 2011
44Matsumoto T, Shimizu T, Aoshima Y, Oda H, Kikuchi K, Katsura H, Fujiwara T, Onuki T.
Endobronchial hamartoma with obstructive pneumonia due to Nocardia asiatica.
Gen Thorac Cardiovasc Surg. Feb;59(2):141-4. 2011
45Matsuo M, Hishinuma T, Katayama Y, Cui L, Kapi M, Hiramatsu K.
Mutation of RNA Polymerase {beta} Subunit (rpoB) Promotes hVISA-to-VISA Phenotypic Conversion of Strain Mu3.
Antimicrob Agents Chemother. Sep;55(9):4188-95. 2011
46Miyahara K, Kato Y, Koga H, Dizon R, Lane GJ, Suzuki R, Akazawa C, Yamataka A.
Visualization of enteric neural crest cell migration in SOX10 transgenic mouse gut using time-lapse fluorescence imaging.
J Pediatr Surg. Dec;46(12):2305-8. 2011
47Miyano G, Hayashi T, Arakawa A, Nawata M, Takasaki Y, Tanaka N, Lane GJ, Kato Y, Yamataka A, Okazaki T.
Choledochal cyst and systemic lupus erythematosus.
Pediatr Surg Int. Jan;27(1):111-3. 2011
48Miyano G, Koga H, Shimotakahara A, Takahashi T, Kato Y, Lane GJ, Okazaki T, Yamataka A.
Intralaparoscopic endoscopy: its value during laparoscopic repair of choledochal cyst.
Pediatr Surg Int. May;27(5):463-6. 2011
49Miyano G, Miyahara K, Halibieke A, Lane GJ, Okazaki T, Yamataka A.
Intraabdominal laparoscopy-assisted "open" vessel ligation of testicular vessels: a potential treatment for varicocele.
J Laparoendosc Adv Surg Tech A. Oct;21(8):749-51. 2011
50Miyano G, Urao M, Lane GJ, Kato Y, Okazaki T, Yamataka A.
A prospective analysis of endoloops and endostaples for closing the stump of the appendix in children.
J Laparoendosc Adv Surg Tech A. Mar;21(2):177-9. 2011
51Miyano G, Urao M, Lane GJ, Kato Y, Okazaki T, Yamataka A.
Appendiceal stump closure in children with complicated appendicitis: A prospective analysis of endoloops versus endostaples.
Asian J Endosc Surg 4. 116–119. 2011
52Mori H, Sakamoto N, Osada T, Ritsuno H, Hidaka Y, Nakae K, Matsumoto K, Beppu K, Shibuya T, Yoshizawa T, Nagahara A, Otaka M, Ogihara T, Arai F, Watanabe S.
The 'Loop Clip' is useful for closing large mucosal defects after colorectal endoscopic submucosal dissection: a preliminary clinical study.
Dig Endosc. Oct;23(4):330-1. 2011
53Murakami T, Suzuki K, Tamura H, Nagaoka I.
Suppressive actions of resolvin D1 on the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice.
Exp Ther Med Jan - Feb. 2: 57-61 2011
54Nagaoka I, Igarashi M, Hua J, Yomogida S, Sakamoto K.
Recent aspects of the anti-inflammatory actions of glucosamine.
Carbohydrate Polymers Mar 84: 825-830. 2011
55Nakajima K, Nagahara A, Kurosawa A, Seyama K, Asaoka D, Osada T, Hojo M, Watanabe S.
Quit smoking improves gastroesophageal reflux symptoms and quality of life.
Health 3(11)677-83. 2011
56Nakano H, Ushio H.
An unexpected role for autophagy in degranulation of mast cells.
Autophagy. Jun;7(6):657-9. 2011
57Ng W, Ikeda S.
Standardized, defined serum-free culture of a human skin equivalent on fibroblast-populated collagen scaffold.
Acta Derm Venereol. Jun;91(4):387-91. 2011
58Ng W, Ikeda S.
Use of sun-protective items by Japanese pedestrians: a cross-sectional observational study.
Arch Dermatol. Oct;147(10):1167-70. 2011
59Ogawa T, Kasahara K, Yonekawa S, Nakagawa C, Maeda K, Konishi M, Mikasa K, Kikuchi K.
Nocardia beijingensis pulmonary infection successfully treated with intravenous beta-lactam antibiotics and oral minocycline.
J Infect Chemother. Oct;17(5):706-9. 2011
60Oguro M, Koike M, Ueno T, Asaoka D, Mori H, Nagahara A, Uchiyama Y, Watanabe S.
Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease.
J Gastroenterol. May;46(5):629-38. 2011
61Ohashi R, Kato M, Katsura Y, Takekawa H, Hoshika Y, Sugawara T, Yoshimi K, Togo S, Nagaoka T, Seyama K, Takahashi K, Tsuchiya K, Misawa S, Kikuchi K.
Breakthrough lung Scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance (MGUS).
Med Mycol J. Mar 52(1):33-8. 2011
62Ohtsuka Y, Okada K, Yamakawa Y, Ikuse T, Baba Y, Inage E, Fujii T, Izumi H, Oshida K, Nagata S, Yamashiro Y, Shimizu T.
ω-3 fatty acids attenuate mucosal inflammation in premature rat pups.
J Pediatr Surg. Mar;46(3):489-95. 2011
63Okazaki T, Nakazawa N, Ogasawara Y, Shoji H, Shimizu T, Makino S, Takeda S, Lane GJ, Yamataka A.
Increase in fetal pulmonary artery diameters during late gestation is a predictor of outcome in congenital diaphragmatic hernia with liver herniation.
J Pediatr Surg. Dec;46(12):2254-9. 2011
64Okazaki T, Nishimura K, Takahashi T, Shoji H, Shimizu T, Tanaka T, Takeda S, Inada E, Lane GJ, Yamataka A.
Indications for thoracoscopic repair of congenital diaphragmatic hernia in neonates.
Pediatr Surg Int. Jan;27(1):35-8. 2011
65Osada T, Arakawa A, Sakamoto N, Ueyama H, Shibuya T, Ogihara T, Yao T, Watanabe S.
Autofluorescence imaging endoscopy for identification and assessment of inflammatory ulcerative colitis.
World J Gastroenterol. Dec 14;17(46):5110-6. 2011
66Penaloza-MacMaster P, Ur Rasheed A, Iyer SS, Yagita H, Blazar BR, Ahmed R.
Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice.
J Virol. Jul;85(13):6168-74. 2011
67Piao JH, Hasegawa M, Heissig B, Hattori K, Takeda K, Iwakura Y, Okumura K, Inohara N, Nakano H.
Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease.
J Biol Chem. May 20;286(20):17879-88. 2011
68Ritsuno H, Sakamoto N, Mitomi H, Namihisa A, Mori H, Nakae K, Matsumoto K, Beppu K, Shibuya T, Osada T, Nagahara A, Otaka M, Terai T, Ogihara T, Yao T, Watanabe S.
Advanced colorectal cancer with double-hump camel-like appearance.
Dig Endosc. Oct;23(4):329. 2011
69Salek-Ardakani S, Flynn R, Arens R, Yagita H, Smith GL, Borst J, Schoenberger SP, Croft M.
The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice.
J Clin Invest. Jan 4;121(1):296-307. 2011
70Sato-Hayashizaki A, Ohtsuji M, Lin Q, Hou R, Ohtsuji N, Nishikawa K, Tsurui H, Sudo K, Ono M, Izui S, Shirai T, Takai T, Nishimura H, Hirose S.
Presumptive role of 129 strain-derived Sle16 loeus for rheumatoid arthritis in a new mouse model with FcγRIIB-deficient C57BL/6 genetic backgraound Arthritis Rheum.
Oct;63(10):2930-8. 2011
71Shibuya T, Ohkusa T, Yokoyama T, Matsumoto K, Beppu K, Sakamoto N, Osada T, Nagahara A, Otaka M, Ogihara T, Watanabe S.
Colonic mucosal lesions associated with low-dose aspirin: a case control study.
Scand J Gastroenterol 46,810-817. 2011
72Shimotakahara A, Nakazawa N, Wada A, Nagata S, Koga H, Takahashi T, Miyano G, Lane GJ, Yamataka A.
Tubularized incised plate urethroplasty with dorsal inlay graft prevents meatal/neourethral stenosis: a single surgeon's experience.
J Pediatr Surg. Dec;46(12):2370-2. 2011
73Shoji H, Hisata K, Suzuki M, Yoshikawa N, Suganuma H, Ohkawa N, Shimizu T.
Effects of parenteral soybean oil lipid emulsion on the long-chain polyunsaturated fatty acid profile in very-low-birth-weight infants.
Acta Paediatr. Jul;100(7):972-6. 2011
74Shoji M, Cui L, Iizuka R, Komoto A, Neoh HM, Watanabe Y, Hishinuma T, Hiramatsu K.
WalK and ClpP Mutations Confer Decreased Susceptibility to Vancomycin in Staphylococcus aureus.
Antimicrob Agents Chemother. Aug;55(8):3870-81. 2011
75Shukuya R, Hasegawa T, Niwa Y, Okuma K, Ikeda S.
Granulocyte and monocyte adsorption apheresis for generalized pustular psoriasis.
J Dermatol. Dec;38(12):1130-4. 2011
76Sugasawa Y, Yamaguchi K, Kumakura S, Murakami T, Kugimiya T, Suzuki K, Nagaoka I, Inada E.
The effect of one-lung ventilation upon pulmonary inflammatory responses during lung resection.
J Anesth. Apr;25(2):170-7. 2011
77Sugiyama R, Hayafune M, Habu Y, Yamamoto N, Takaku H.
HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses.
Nucleic Acids Res. Jan;39(2):589-98. 2011
78Suzuki K, Murakami T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I.
Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells.
Int Immunol. Mar;23(3):185-93. 2011
79Suzuki K, Nagaoka I.
Effect of antimicrobial cathelicidin peptides on the endothelial cell apoptosis.
Inflamm Regener 31(4):375-381. 2011
80Tajima K, Miura K, Ishiwata T, Takahashi F, Yoshioka M, Minakata K, Murakami A, Sasaki S, Iwakami S, Annoura T, Hashimoto M, Nara T, Takahashi K.
Sex hormones alter Th1 responses and enhance granuloma formation in the lung.
Respiration. 81(6):491-498. 2011
81Takahashi T, Koga H, Tanaka T, Shoji H, Takeda S, Shimizu T, Lane GJ, Yamataka A, Okazaki T.
Pulmonary artery size has prognostic value in low birth weight infants with congenital diaphragmatic hernia.
Pediatr Surg Int. Aug;27(8):847-50. 2011
82Takai T, Ikeda S.
Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases.
Allergol Int. 2011 Mar;60(1):25-35. 2011
83Tamaki K, Otaka M, Takada M, Yamamoto S, Odashima M, Itoh H, Watanabe S.
Evidence for enhanced cytoprotective function of HSP90-overexpressing small intestinal epithelial cells.
Dig Dis Sci. Jul;56(7):1954-61. 2011
84Taniguchi G, Nagahara A, Matsumoto K, Ritsuno H, Igusa Y, Sasaki H, Beppu K, Shibuya T, Sakamoto N, Osada T, Kawabe M, Terai T, Ogihara T, Watanabe S.
Asymptomatic anisakiasis of the colon incidentally found by colonoscopy.
Clin J Gastroenterol 4(6):371-73. 2011
85Tokunaga F, Nakagawa T, Nakahara M, Saeki Y, Taniguchi M, Sakata S, Tanaka K, Nakano H, Iwai K.S
HARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex.
Nature. Mar 31;471(7340):633-6. 2011
86Ushio H, Ueno T, Kojima Y, Komatsu M, Tanaka S, Yamamoto A, Ichimura Y, Ezaki J, Nishida K, Komazawa-Sakon S, Niyonsaba F, Ishii T, Yanagawa T, Kominami E, Ogawa H, Okumura K, Nakano H.
Crucial role for autophagy in degranulation of mast cells.
J Allergy Clin Immunol. May;127(5):1267-76.e6. 2011
87Vu AT, Chen X, Xie Y, Kamijo S, Ushio H, Kawasaki J, Hara M, Ikeda S, Okumura K, Ogawa H, Takai T.
Extracellular Double-Stranded RNA Induces TSLP via an Endosomal Acidification-and NF-kB-Dependent Pathway in Human Keratinocytes.
J Invest Dermatol. Nov;131(11):2205-12. 2011
88Wang X, Ikejima K, Kon K, Arai K, Aoyama T, Okumura K, Abe W, Sato N, Watanabe S.
Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells.
J Hepatol. Aug;55(2):379-87. 2011
89Watanabe S, Enomoto N, Koike K, Izumi N, Takikawa H, Hashimoto E, Moriyasu F, Kumada H, Imawari M.
PERFECT Study Group.Cancer preventive effect of pegylated interferon α-2b plus ribavirin in a real-life clinical setting in Japan: PERFECT interim analysis.
Hepatol Res. Oct;41(10):955-64. 2011
90Watanabe Y, Cui L, Katayama Y, Kishii K, Hiramatsu K.
Impact of RpoB Mutations on Decreased Susceptibility to Vancomycin in Staphylococcus aureus.
J Clin Microbiol. Jul;49(7):2680-4. 2011
91Watanabe Y, Naito T, Kikuchi K, Amari Y, Uehara Y, Isonuma H, Hisaoka T, Yoshida T, Yaginuma K, Takaya N, Daida H, Hiramatsu K.
Infective endocarditis with Lactococcus garvieae in Japan: a case report.
J Med Case Reports. Aug 9;5(1):356. 2011
92Yamaguchi K, Sugasawa Y, Takeuchi K, Kugimiya T, Kumakura S, Iwanuma Y, Kajiyama Y, Tsurumaru M, Nagaoka I, Inada E.
Effects of sivelestat on bronchial inflammatory responses after esophagectomy.
Int J Mol Med. Aug;28(2):187-92. 2011
93Yamazaki S, Okada K, Maruyama A, Matsumoto M, Yagita H, Seya T.
TLR2-dependent induction of IL-10 and Foxp3+CD25+CD4+ regulatory T cells prevents effective anti-tumor immunity induced by Pam2 lipopeptides in vivo.
PLoS One Apr 20;6(4):e18833. 2011
94Yanagisawa N, Haruta I, Kikuchi K, Shibata N, Yagi J.
Are Dysregulated Inflammatory Responses to Commensal Bacteria Involved in the Pathogenesis of Hepatobiliary-Pancreatic Autoimmune Disease? An Analysis Using Mice Models of Primary Biliary Cirrhosis and Autoimmune Pancreatitis.
ISRN Gastroenterol. 2011:513514. 2011
95Yasuma A, Ochiai T, Azuma M, Nishiyama H, Kikuchi K, Kondo M, Handa H.
Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions.
J Med Microbiol. Jul;60(Pt 7):1038-42. 2011
96Zhang M, Ito T, Li S, Jin J, Takeuchi F, Lauderdale TL, Higashide M, Hiramatsu K.
Identification of the third type of PVL phage in ST59 methicillin-resistant Staphylococcus aureus (MRSA) strains.
FEMS Microbiol Lett. Oct;323(1):20-8. 2011
97Zhang M, O'Donoghue MM, Ito T, Hiramatsu K, Boost MV.
Prevalence of antiseptic-resistance genes in Staphylococcus aureus and coagulase-negative staphylococci colonising nurses and the general population in Hong Kong.
J Hosp Infect. Jun;78(2):113-7. 2011

英文原著(2010年)

1Ando K, Hasegawa K, Shindo K, Furusawa T, Fujino T, Kikugawa K, Nakano H, Takeuchi O, Akira S, Akiyama T, Gohda J, Inoue J, Hayakawa M.
Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling.
FEBS J. May;277(9):2051-66. 2010
2Ando S, Amano H, Amano E, Minowa K, Watanabe T, Nakano S, Nakiri Y, Morimoto S, Tokano Y, Lin Q, Hou R, Ohtsuji M, Tsurui H, Hirose S, Takasaki Y.
FTY720 exerts a survival advantage through the prevention of end-stage glomerular inflammation in lupus-prone BXSB mice.
Biochem Biophys Res Commun. Apr 9;394(3):804-10. 2010
3Beppu K, Nagahara A, Terai T, Matsumoto K, Shibuya T, Sakamoto N, Osada T, Kawabe M, Otaka M, Ogihara T, Watanabe S.
Clinicopathological characteristics of colorectal cancer less than 10 mm in diameter and invading submucosa and below.
J Gastroenterol Hepatol. May;25 Suppl 1:S57-61. 2010
4Chiba Y, Shida K, Nagata S, Wada M, Bian L, Wang C, Shimizu T, Yamashiro Y, Kiyoshima-Shibata J, Nanno M, Nomoto K.
Well-controlled proinflammatory cytokine responses of Peyer's patch cells to probiotic Lactobacillus casei.
Immunology. Jul;130(3):352-62. 2010
5Cui L, Isii T, Fukuda M, Ochiai T, Neoh HM, Camargo IL, Watanabe Y, Shoji M, Hishinuma T, Hiramatsu K.
An RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus.
Antimicrob Agents Chemother. Dec;54(12):5222-33. 2010
6Dias P, Giannoni F, Lee LN, Han D, Yoon S, Yagita H, Azuma M, Sarawar SR.
CD4 T-cell help programs a change in CD8 T-cell function enabling effective long-term control of murine gammaherpesvirus 68: role of PD-1-PD-L1 interactions.
J Virol. Aug;84(16):8241-9. 2010
7Fujimori M, Hisata K, Nagata S, Matsunaga N, Komatsu M, Shoji H, Sato H, Yamashiro Y, Asahara T, Nomoto K, Shimizu T.
Efficacy of bacterial ribosomal RNA-targeted reverse transcription-quantitative PCR for detecting neonatal sepsis: a case control study.
BMC Pediatr. Jul 29;10:53. 2010
8Fujimura J, Takeda K, Kaduka Y, Saito M, Akiba H, Yagita H, Yamashiro Y, Shimizu T, Okumura K.
Contribution of B7RP-1/ICOS co-stimulation to lethal acute GVHD.
Pediatr Transplant. Jun;14(4):540-8. 2010
9Fukuo Y, Shibuya T, Fukumura Y, Mizui T, Sai JK, Nagahara A, Tsukada A, Matsumoto T, Suyama M, Watanabe S.
Reactive lymphoid hyperplasia of the liver associated with primary biliary cirrhosis.
Med Sci Monit. Jul;16(7):CS81-6. 2010
10Furukawa T, Kishiro M, Fukunaga H, Ohtsuki M, Takahashi K, Akimoto K, Shimizu T, Kawasaki S, Kumasaka T.
Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo.
Pediatr Cardiol. Aug;31(6):773-9. 2010
11Haruna K, Suga Y, Oizumi A, Mizuno Y, Endo H, Shimizu T, Hasegawa T, Ikeda S.
Severe form of keratitis-ichthyosis-deafness (KID) syndrome associated with septic complications.
J Dermatol. Jul;37(7):680-2. 2010
12Haruta I, Kikuchi K, Hashimoto E, Nakamura M, Miyakawa H, Hirota K, Shibata N, Kato H, Arimura Y, Kato Y, Uchiyama T, Nagamune H, Kobayashi M, Miyake Y, Shiratori K, Yagi J.
Long-term bacterial exposure can trigger nonsuppurative destructive cholangitis associated with multifocal epithelial inflammation.
Lab Invest. Apr;90(4):577-88. 2010
13Hasegawa T, Suga Y, Mizuno Y, Haruna K, Ogawa H, Ikeda S.
Efficacy of photodynamic therapy with topical 5-aminolevulinic acid using intense pulsed light for Bowen's disease.
J Dermatol. Jul;37(7):623-8. 2010
14Hasegawa T,Matsukura T, Ikeda S.
Mesotherapy for benign symmetrical lipomatosis.
Aesthetic Plast Surg,Apr;34(2):153-156 2010
15Higashiyama M, Ito T, Han X, Ono K, Minamimura K, Sakakibara F, Tanno A, Nishiyama J, Hatada J, Hiramatsu K, Kawana A.
Epidural abscess caused by community-associated methicillin-resistant Staphylococcus aureus strain USA300 in Japan.
J Infect Chemother. Oct;16(5):345-9. 2010
16Inami K, Abe M, Takeda K, Hagiwara Y, Maeda M, Segawa T, Suyama M, Watanabe S, Hino O.
Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo.
Cancer Sci. Apr;101(4):969-74. 2010
17Iwabuchi K, Nakayama H, Iwahara C, Takamori K.
Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction.
FEBS Lett. May 3;584(9):1642-52. 2010
18Kaneko N, Hisata K, Shoji H, Tanaka K, Nakazawa T, Shimizu T.
Effects of early enteral feeding on fecal elastase 1 and plasma secretin.
Pediatr Int. Aug;52(4):607-10. 2010
19Kato J, Nagahara A, Iijima K, Kodani T, Higashihara Y, Yoshimura M, Serizawa N, Osada T, Yoshizawa T, Otaka M, Watanabe S.
Phase I study of paclitaxel, cisplatin and 5-fluorouracil combination chemotherapy for unresectable / recurrent gastric cancer.
Adv Med Sci. Dec 30;55(2):137-42. 2010
20Koga H, Miyano G, Takahashi T, Shimotakahara A, Kato Y, Lane GJ, Okazaki T, Yamataka A.
Comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus.
J Pediatr Surg. Dec;45(12):2394-7. 2010
21Koga H, Okazaki T, Kato Y, Lane GJ, Yamataka A.
Anal canal duplication: experience at a single institution and literature review.
Pediatr Surg Int. Oct;26(10):985-8. 2010
22Kohama H, Harakuni T, Kikuchi M, Nara T, Takemura Y, Miyata T, Sato Y, Hirayama K, Arakawa T.
Intranasal administration of Schistosoma japonicum paramyosin induced robust long-lasting systemic and local antibody as well as delayed-type hypersensitivity responses, but failed to confer protection in a mouse infection model.
Jpn J Infect Dis. May;63(3):166-72. 2010
23Komiyama M, Fu K, Morimoto T, Konuma H, Yamagata T, Izumi Y, Miyazaki A, Watanabe S.
A novel endoscopic ablation of gastric antral vascular ectasia.
World J Gastrointest Endosc. Aug 16;2(8):298-300. 2010
24Kon K, Ikejima K, Okumura K, Arai K, Aoyama T, Watanabe S.
Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen.
Am J Physiol Gastrointest Liver Physiol. Aug;299(2):G329-37. 2010
25Kon K, Kim JS, Uchiyama A, Jaeschke H, Lemasters JJ.
Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes.
Toxicol Sci. Sep;117(1):101-8. 2010
26Kudo T, Aoyagi Y, Fujii T, Ohtsuka Y, Nagata S, Shimizu T.
Development of Candida albicans colitis in a child undergoing steroid therapy for ulcerative colitis.
J Pediatr Gastroenterol Nutr. Jul;51(1):96-9. 2010
27Le TA, Takai T, Vu AT, Kinoshita H, Ikeda S, Ogawa H, Okumura K.
Glucocorticoids inhibit double-stranded RNA-induced thymic stromal lymphopoietin release from keratinocytes in an atopic cytokine milieu more effectively than tacrolimus.
Int Arch Allergy Immunol. 153(1):27-34. 2010
28Lin Q, Hou R, Sato A, Ohtsuji M, Ohtsuji N, Nishikawa K, Tsurui H, Amano H, Amano E, Sudo K, Nishimura H, Shirai T, Hirose S.
Inhibitory IgG Fc receptor promoter region polymorphism is a key genetic element for murine systemic lupus erythematosus.
J Autoimmun. Jun;34(4):356-63. 2010
29Lkhagvadorj E, Nagata S, Wada M, Bian L, Wang C, Chiba Y, Yamashiro Y, Shimizu T, Asahara T, Nomoto K.
Anti-infectious activity of synbiotics in a novel mouse model of methicillin-resistant Staphylococcus aureus infection.
Microbiol Immunol. May;54(5):265-75. 2010
30Missiou A, Rudolf P, Stachon P, Wolf D, Varo N, Aichele P, Colberg C, Hoppe N, Ernst S, Münkel C, Walter C, Sommer B, Hilgendorf I, Nakano H, Bode C, Zirlik A.
TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.
Circ Res. Sep 17;107(6):757-66. 2010
31Miyahara K, Kato Y, Koga H, Lane GJ, Inoue T, Akazawa C, Yamataka A.
Abnormal enteric innervation identified without histopathologic staining in aganglionic colorectum from a mouse model of Hirschsprung's disease.
J Pediatr Surg. Dec;45(12):2403-7. 2010
32Miyano G, Okazaki T, Kato Y, Marusasa T, Takahashi T, Lane GJ, Yamataka A.
Open versus laparoscopic treatment for pan-peritonitis secondary to perforated appendicitis in children: a prospective analysis.
J Laparoendosc Adv Surg Tech A. Sep;20(7):655-7. 2010
33Mori H, Shibuya T, Osada T, Kodani T, Higashihara Y, Serizawa N, Kato J, Nagahara A, Ogihara T, Watanabe S.
Response to chemotherapy in a case of gastric adenocarcinoma producing granulocyte colony-stimulating factor.
Med Sci Monit. 2010 Oct;16(10):CS119-23. 2010
34Morimoto T, Fu KI, Konuma H, Izumi Y, Asano A, Kokubu S, Miyazaki A, Watanabe S.
Endoscopic hemostasis with hemoclips for active gastric variceal bleeding. Endoscopy.
42 Suppl 2:E333-4. 2010
35Morimoto T, Fu KI, Konuma H, Izumi Y, Matsuyama S, Ogura K, Miyazaki A, Watanabe S.
Peeling a giant ileal lipoma with endoscopic unroofing and submucosal dissection.
World J Gastroenterol. Apr 7;16(13):1676-9. 2010
36Nagahara A, Asaoka D, Hojo M, Oguro M, Shimada Y, Ishikawa D, Osada T, Kawabe M, Yoshizawa T, Otaka M, Watanabe S.
Observational comparative trial of the efficacy of proton pump inhibitors versus histamine-2 receptor antagonists for uninvestigated dyspepsia.
J Gastroenterol Hepatol. May;25 Suppl 1:S122-8. 2010
37Nagahara A, Hojo M, Asaoka D, Watanabe S.
Maintenance therapy of gastroesophageal reflux disease.
Clin J Gastroenterol April;3(2)61-68 2010
38Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M.
Evaluation of the effect of α-defensin human neutrophil peptides on neutrophil apoptosis.
Int J Mol Med. Dec;26(6):925-34. 2010
39Nakagawa C, Kasahara K, Yonekawa S, Ogawa T, Kutsuna S, Maeda K, Konishi M, Kikuchi K, Mikasa K.
Purulent pericarditis due to Streptococcus pneumoniae diagnosed by pneumococcal urinary antigen assay and 16S rDNA sequence of the pericardial fluid.
Intern Med. 2010;49(15):1653-6. 2010
40Niwa Y, Potaczek DP, Kanada S, Takagi A, Shimokawa N, Ito T, Mitsuishi K, Okubo Y, Tajima M, Hobo A, Ng W, Tsuboi R, Ikeda S, Ogawa H, Okumura K, Nishiyama C.
FcepsilonRIalpha gene (FCER1A) promoter polymorphisms and total serum IgE levels in Japanese atopic dermatitis patients.
Int J Immunogenet. Apr;37(2):139-41. 2010
41Niyonsaba F, Ushio H, Hara M, Yokoi H, Tominaga M, Takamori K, Kajiwara N, Saito H, Nagaoka I, Ogawa H, Okumura K.
Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells.
J Immunol. Apr 1;184(7):3526-34. 2010
42Obinata K, Okumura A, Nakazawa T, Kamata A, Niizuma T, Kinoshita K, Shimizu T.
Norovirus encephalopathy in a previously healthy child.
Pediatr Infect Dis J. Nov;29(11):1057-9. 2010
43Ohata R, Okazaki T, Ishizaki Y, Fujimura J, Shimizu T, Lane GJ, Yamataka A, Kawasaki S.
Pancreaticoduodenectomy for pancreatoblastoma: a case report and literature review.
Pediatr Surg Int. Apr;26(4):447-50. 2010
44Ohji G, Kikuchi K, Inoue K, Imoto K, Yamamoto S, Hosokawa N, Kamei K, Iwata K.
Progressive disseminated histoplasmosis in an immunocompetent patient as an underrecognized imported mycosis in Japan.
J Infect Chemother. Dec;16(6):443-5. 2010
45Ohtani K, Ohtsuka Y, Ikuse T, Baba Y, Yamakawa Y, Aoyagi Y, Fujii T, Kudo T, Nagata S, Shimizu T.
Increased mucosal expression of GATA-3 and STAT-4 in pediatric ulcerative colitis.
Pediatr Int. Aug;52(4):584-9. 2010
46Ohtsuki A, Hasegawa T, Ikeda S.
Treatment of alopecia areata with 308-nm excimer lamp.
J Dermatol. Dec;37(12):1032-5. 2010
47Okazaki T, Ohata R, Miyano G, Lane GJ, Takahashi T, Yamataka A.
Laparoscopic splenopexy and gastropexy for wandering spleen associated with gastric volvulus.
Pediatr Surg Int. Oct;26(10):1053-5. 2010
48Okubo H, Kokubu S, Komiyama M, Yamagata H, Uchiyama A, Miyazaki A, Watanabe S.
Radiofrequency ablation of hepatocellular carcinoma: The feasibility of magnetic resonance imaging with gadolinium ethoxybenzyl diethylene triamine pentaacetic acid for evaluating the ablative margin.
Hepatology Research 40(10):1034-41 2010
49Sai JK, Suyama M, Kubokawa Y, Matsumura Y, Inami K, Watanabe S, Kirino E.
Identification of cerebral response to balloon distention of the bile duct.
World J Gastroenterol. Apr 14;16(14):1772-5. 2010
50Saito Y, Uraoka T, Yamaguchi Y, Hotta K, Sakamoto N, Ikematsu H, Fukuzawa M, Kobayashi N, Nasu J, Michida T, Yoshida S, Ikehara H, Otake Y, Nakajima T, Matsuda T, Saito D.
A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video).
Gastrointest Endosc. Dec;72(6):1217-25. 2010
51Sakaguchi S, Saito M, Tsuji H, Asahara T, Takata O, Fujimura J, Nagata S, Nomoto K, Shimizu T.
Bacterial rRNA-targeted reverse transcription-PCR used to identify pathogens responsible for fever with neutropenia.
J Clin Microbiol. 2010 May;48(5):1624-8.
52Shibuya T, Ohkusa T, Yokoyama T, Harada A, Beppu K, Sakamoto N, Osada T, Nagahara A, Terai T, Otaka M, Ogihara T, Watanabe S.
Colonic mucosal lesions associated with long-term or short-term administration of nonsteroidal anti-inflammatory drugs.
Colorectal Dis. Nov;12(11):1113-21. 2010
53Shibuya T, Osada T, Mitomi H, Takeda T, Nomura O, Nakayama H, Hidaka Y, Mori H, Beppu K, Sakamoto N, Nagahara A, Otaka M, Ogihara T, Yao T, Watanabe S.
Jejunal capillary hemangioma treated by using double-balloon endoscopy (with video) .
Gastrointest Endosc. Sep;72(3):660-1. 2010
54Shimotakahara A, Sueyoshi R, Lane GJ, Okazaki T, Nishimura K, Inada E, Yamataka A.
The benefit of stay sutures during thoracoscopic esophagoesophagostomy in patients with esophageal atresia: a technical report.
Pediatr Surg Int. Apr;26(4):443-6. 2010
55Shimura E, Hozumi N, Kanagawa O, Metzger D, Chambon P, Radtke F, Hirose S, Nakano N.
Epidermal gammadelta T cells sense precancerous cellular dysregulation and initiate immune responses.
Int Immunol. Apr;22(4):329-40. 2010
56Shono T, Kato M, Aoyagi Y, Haruna H, Fujii T, Kudo T, Ohtsuka Y, Shimizu T.
Assessment of Growth Disturbance in Japanese Children with IBD.
Int J Pediatr. 2010:958915. 2010
57Someya A, Moss J, Nagaoka I.
The guanine nucleotide exchange protein for ADP-ribosylation factor 6, ARF-GEP100/BRAG2, regulates phagocytosis of monocytic phagocytes in an ARF6-dependent process.
J Biol Chem. Oct 1;285(40):30698-707. 2010
58Suganuma H, Arai Y, Kitamura Y, Hayashi M, Okumura A, Shimizu T.
Maternal docosahexaenoic acid-enriched diet prevents neonatal brain injury.
Neuropathology. Dec;30(6):597-605. 2010
59Sugihara E, Naito T, Aiba M, Matsuda N, Shiga T, Amari Y, Haba Y, Mitsuhashi K, Isonuma H, Dambara T.
A case of synovitis acne pustulosis hyperostosis osteitis (SAPHO) syndrome.
General Medicine Dec 11(2) 91-92 2010
60Sugimura R,,Mayuzumi N, Ikeda S.
Effects of Cyclooxygenase-1 or -2 inhibitors on expressions of ATP2A2 and ATP2C1 in cultured normal human keratinocytes.
順天堂医学 56(6) 550-7 2010
61Tajima K, Ohashi R, Sekido Y, Hida T, Nara T, Hashimoto M, Iwakami S, Minakata K, Yae T, Takahashi F, Saya H, Takahashi K.
Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells.
Oncogene. Apr 1;29(13):1941-51. 2010
62Takahashi T, Otaka M, Odashima M, Tamaki K, Takada M, Izumi Y, Shibuya T, Sakamoto N, Itoh H, Watanabe S.
Correlation of heat shock protein expression to gender difference in development of stress-induced gastric mucosal injury in rats.
J Clin Biochem Nutr. 2010 Jul;47(1):64-73. 2010
63Takamiya S, Fukuda K, Nakamura T, Aoki T, Sugiyama H.
Paragonimus westermani possesses aerobic and anaerobic mitochondria in different tissues, adapting to fluctuating oxygen tension in microaerobic habitats.
Int J Parasitol. Dec;40(14):1651-8. 2010
64Takamura S, Tsuji-Kawahara S, Yagita H, Akiba H, Sakamoto M, Chikaishi T, Kato M, Miyazawa M.
Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors.
J Immunol. May 1;184(9):4696-707. 2010
65Takeichi N, Yanagisawa S, Kaneyama T, Yagita H, Jin YH, Kim BS, Koh CS.
Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Int Immunol. Sep;22(9):729-38. 2010
66Tanaka K, Yoshikawa N, Kudo N, Negishi Y, Shimizu T, Hayata N.
A need for play specialists in Japanese children's wards.
Paediatr Nurs. Jul;22(6):31-2. 2010
67Tasew G, Nylén S, Lieke T, Lemu B, Meless H, Ruffin N, Wolday D, Asseffa A, Yagita H, Britton S, Akuffo H, Chiodi F, Eidsmo L.
Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration.
PLoS Negl Trop Dis. Oct 12;4(10):e844. 2010
68Tomoyasu T, Tabata A, Hiroshima R, Imaki H, Masuda S, Whiley RA, Aduse-Opoku J, Kikuchi K, Hiramatsu K, Nagamune H.
Role of catabolite control protein A in the regulation of intermedilysin production by Streptococcus intermedius.
Infect Immun. Sep;78(9):4012-21. 2010
69Torii H, Nakagawa H.Japanese Infliximab Study investigators.
Infliximab monotherapy in Japanese patients with moderate-to-severe plaque psoriasis and psoriatic arthritis. A randomized, double-blind, placebo-controlled multicenter trial.
J Dermatol Sci. Jul;59(1):40-9. 2010
70Tsubakishita S, Kuwahara-Arai K, Baba T, Hiramatsu K.
Staphylococcal cassette chromosome mec-like element in Macrococcus caseolyticus.
Antimicrob Agents Chemother. Apr;54(4):1469-75. 2010
71Tsubakishita S, Kuwahara-Arai K, Sasaki T, Hiramatsu K.
Origin and molecular evolution of the determinant of methicillin resistance in staphylococci.
Antimicrob Agents Chemother. Oct;54(10):4352-9. 2010
72Uehara Y, Takahashi T, Yagoshi M, Shimoguchi K, Yanai M, Kumasaka K, Kikuchi K.
Liver abscess of Actinomyces israelii in a hemodialysis patient: case report and review of the literature.
Intern Med. 2010;49(18):2017-20. 2010
73Ueyama H, Yao T, Nakashima Y, Hirakawa K, Oshiro Y, Hirahashi M, Iwashita A, Watanabe S.
Gastric adenocarcinoma of fundic gland type (chief cell predominant type): proposal for a new entity of gastric adenocarcinoma.
Am J Surg Pathol. May;34(5):609-19. 2010
74Vu AT, Baba T, Chen X, Le TA, Kinoshita H, Xie Y, Kamijo S, Hiramatsu K, Ikeda S, Ogawa H, Okumura K, Takai
T.
Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes through the Toll-like receptor 2-Toll-like receptor 6 pathway.
J Allergy Clin Immunol. Nov;126(5):985-93, 993.e1-3. 2010
75Wada M, Nagata S, Saito M, Shimizu T, Yamashiro Y, Matsuki T, Asahara T, Nomoto K.
Effects of the enteral administration of Bifidobacterium breve on patients undergoing chemotherapy for pediatric malignancies.
Support Care Cancer. Jun;18(6):751-9. 2010
76Yamaguchi K, Kawahara T, Kumakura S, Hua J, Kugimiya T, Nagaoka I, Inada E.
Effect of olprinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats.
Shock. Apr;33(4):436-41. 2010

英文原著(2009年)

1Barnor JS, Habu Y, Yamamoto N, Miyano-Kurosaki N, Ishikawa K, Yamamoto N, Takaku H.
Inhibition of HIV-1 replication by long-term treatment with a chimeric RNA containing shRNA and TAR decoy RNA.
Antiviral Research. Aug;83(2):156-64. 2009
2Dewan MZ, Tomita M, Katano H, Yamamoto N, Ahmed S, Yamamoto M, Sata T, Mori N, Yamamoto N.
An HIV protease inhibitor, ritonavir targets the nuclear factor-kappaB and inhibits the tumor growth and infiltration of EBV-positive lymphoblastoid B cells.
Int J Cancer. 1;124(3):622-9. 2009
3Fukumura Y, Masaoka A, Naito T, Kimura M, Yao T.
A case of non-invasive serous adenocarcinoma at unilateral fimbria with spread to the peritoneal/uterine cavity: case report.
Diagn Pathol. 4:43-46 2009
4Han X, Ito T, Takeuchi F, Ma XX, Takasu M, Uehara Y, Oliveira DC, de Lencastre H, Hiramatsu K.
Identification of a novel variant of staphylococcal cassette chromosome mec, type II.5, and Its truncated form by insertion of putative conjugative transposon Tn6012.
Antimicrob Agents Chemother. Jun;53(6):2616-9. 2009
5Hongo I, Baba T, Oishi K, Morimoto Y, Ito T, Hiramatsu K.
Phenol-soluble modulin alpha 3 enhances the human neutrophil lysis mediated by Panton-Valentine leukocidin.
J Infect Dis. Sep 1;200(5):715-23. 2009
6Katayama Y, Murakami-Kuroda H, Cui L, Hiramatsu K.
Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem.
Antimicrob Agents Chemother. Aug;53(8):3190-6. 2009
7Koikawa, N., Nakamura, A., Nagaoka I., Aoki, K., Sawaki, K., Suzuki, Y.
Delayed-onset muscle injury and its modification by wheat gluten hydrolysate.
Nutrition May 25: 493-498 2009
8Komatsu M, Tajima Y, Ito T, Yamashiro Y, Hiramatsu K.
Use of a sensitive chemiluminescence-based assay to evaluate the metabolic suppression activity of linezolid on methicillin-resistant Staphylococcus aureus showing reduced susceptibility to vancomycin.
J Microbiol Biotechnol. Jul;19(7):734-42. 2009
9Matoba K, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Inaoka DK, Kita K, Harada S.
Crystallization and preliminary X-ray analysis of aspartate transcarbamoyrase from the parasitic protist Trypanosoma cruzi.
Acta Crystallogr, 65F, 933-936 2009
10Murakami T, Obata T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I.
Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice.
Int Immunol. Aug;21(8):905-12. 2009
11Niyonsaba F, Nagaoka I, Ogawa H, Okumura K
Multifunctional antimicrobial proteins and peptides: natural activators of immune systems.
Curr Pharm. Des 15:2393-2413, 2009
12Ochiai T, Nishimura K, Watanabe T, Kitajima M, Tsuji M, Nakatani A, Nakayama N, Marusasa T, Mashiko S, Nagaoka I, Futagawa S.
Evaluation of the individual 50% inhibitory are under the concentration curve of 5-fluorouracil based on the collagen gel droplet embedded culture drug sensitivity test in colorectal cancer.
Mol Med Reports May 2(3):405-409 2009
13Ohba K, Ryo A, Dewan MZ, Nishi M, Naito T, Qi X, Inagaki Y, Nagashima Y, Tanaka Y, Okamoto T, Terashima K, Yamamoto N.
Follicular dendritic cells activate HIV-1 replication in monocytes/macrophages through a juxtacrine mechanism mediated by P-selectin glycoprotein ligand 1.
J Immunol. Jul 183; 524-532 2009
14Ohtsuka M, Kikuchi K, Shimizu K, Takahashi N, Ono Y, Sasaki T, Hiramatsu K.
Emergence of quinolone-resistant Bordetella pertussis in Japan.
Antimicrob Agents Chemother. Jul;53(7):3147-9. 2009
15Ohtsuka M, Kikuchi K, Shundo K, Okada K, Higashide M, Sunakawa K, Hiramatsu K.
Improved selective isolation of Bordetella pertussis by use of modified cyclodextrin solid medium.
J Clin Microbiol. Dec;47(12):4164-7. 2009
16Okuda D, Yomogida S, Kuwahara-Arai K, Hitamatsu K, Tamura H, Ohshima T, Maeda N, Nagaoka I.
Augmentation of the antimicrobial activities of guinea pig cathelicidin CAP11-derived peptides by amino acid substitutions.
Int J Mol Med. 2009 Apr;23(4):501-8. 2009
17Watanabe S, Ito T, Sasaki T, Li S, Uchiyama I, Kishii K, Kikuchi K, Skov RL, Hiramatsu K.
Genetic diversity of staphylocoagulase genes (coa): insight into the evolution of variable chromosomal virulence factors in Staphylococcus aureus.
PLoS One. May 27;4(5):e5714. 2009
18Yoshimura M, Sakamoto K, Tsuruta A, Yamamoto T, Ishida K, Yamaguchi H, Nagaoka I.
Evaluation of the effect of glucosamine administration on biomarkers for cartilage and bone metabolism in soccer players.
Int J Mol Med. 2009 Oct;24(4):487-94. 2009

英文原著(2008年)

1Hayashi Y, Okazaki T, Kobayashi H, Lane GJ, Yamataka A.
Shunt conversion before bladder augmentation.
Asian J Surg. Oct;31(4):207-10. 2008
2Takahashi T, Okazaki T, Kato Y, Watoyou H, Lane GJ, Kobayashi H, Segawa O, Kameoka S, Yamataka A.
Laparoscopy-assisted Percutaneous Endoscopic Gastrostomy.
Asian J Surg. Oct;31(4):204-6. 2008

英文原著(2007年)

1Chen, X. Niyonsaba F, Ushio H, Hara M, Yokoi H, Matsumoto K, Saito H, Nagaoka I, Ikeda S, Okumura K, Ogawa H.
Antimicrobial peptides human beta-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability.
Eur. J. Immunol. 37:434-444, 2007.
2Fukushima, A., T. Sumi, K. Fukuda, N. Kumagai, T. Nishida, H. Akiba, K. Okumura, H. Yagita, and H. Ueno.
Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis.
Biochem Biophys Res Commun 353:211-216 . 2007
3Ichikawa S, Ishihara M, Okazaki T, Warabi K, Kato Y, Hori S, Lane GJ , Hiramatsu K, Inada E, Kobayashi H, Yamataka A
Prospective study of antibiotic protocols for managing surgical site infections in children.
J Pediatr Surg. Jun;42(6):1002-7; discussion 1007. 2007
4Kondo Y, Ito T, Ma XX, Watanabe S, Kreiswirth BN, Etienne J, Hiramatsu K.
Combination of multiplex PCRs for SCCmec type assignment: Rapid identification system for mec, ccr, and major differences in junkyard regions.
Antimicrob Agents Chemother 51:264-274. 2007
5Kuroda H, Kuroda M, Cui L, Hiramatsu K.
Subinhibitory concentrations of beta-lactam induce haemolytic activity in Staphylococcus aureus through the SaeRS two-component system.
FEMS Microbiol Lett. 268:98-105. 2007
6Makiuchi T, Nara T, Annoura T, Hashimoto T, Aoki T.
Occurrence of multiple, independent gene fusion events for the fifth and sixth enzymes of pyrimidine biosynthesis in different eukaryotic groups.
Gene. 2007 Jun 1;394(1-2):78-86. 2007
7Marusasa T, Miyano G, Kato Y, Yanai T, Okazaki T, Ichikawa S, Lane GJ, Yamataka A.
New primary management for appendiceal masses in children; laparoscopic drainage.
J Laparoendosc Adv Surg Tech A. Aug;17(4):497-500. 2007
8Miyano G, Yanai T, Okazaki T, Kobayashi H, Lane GJ, Yamataka A.
Laparoscopy-assisted stoma closure.
J Laparoendosc Adv Surg Tech A. Jun;17(3):395-8. 2007
9Murakami, T. Yomogida S, Someya A, Kuwahara-Arai K, Tamura H, Nagaoka I.
Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes.
FEBS Lett. 581: 140-144, 2007.
10Nara T, Iizumi K, Ohmae H, Sy OS, Tsubota S, Inaba Y, Tsubouchi A, Tanabe M, Kojima S, Aoki T.
Antibody isotype responses to paramyosin, a vaccine candidate for schistosomiasis, and their correlations with resistance and fibrosis in patients infected with Schistosoma japonicum in Leyte, The Philippines.
Am J Trop Med Hyg , 76, 384-391. 2007
11Niyonsaba, F., H. Ushio, N. Nakano, W. Ng, K. Sayama, K. Hashimoto, I. Nagaoka, K. Okumura, and H. Ogawa.
Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines.
J Invest Dermatol 127:594-604. 2007
12Ochiai, T. Nishimura K, Noguchi H, Watanabe T, Kitajima M, Konishi N, Sato G, Nagaoka I, Futagawa S.
Evaluation of 5-fluorouracil applicability by the collagen gel droplet embedded drug sensitivity test with area under the curve analysis.
Anticancer. Drugs 18: 17-21, 2007.
13Okazaki T, Iwatani S, Yanai T, Kobayashi H, Kato Y, Marusasa T, Lane GJ, Yamataka A.
Treatment of lymphangioma in children: our experience of 128 cases.
J Pediatr Surg. 2007 Feb;42(2):386-9.
14Sakuma, M., K. Hatsushika, K. Koyama, R. Katoh, T. Ando, Y. Watanabe, M. Wako, M. Kanzaki, S. Takano, H. Sugiyama, Y. Hamada, H. Ogawa, K. Okumura, and A. Nakao.
TGF-beta type I receptor kinase inhibitor down-regulates rheumatoid synoviocytes and prevents the arthritis induced by type II collagen antibody.
Int Immunol 19:117-126 . 2007
15Sasaki T, Kikuchi K, Tanaka Y, Takahashi N, Kamata S, Hiramatsu K.
Methicillin-Resistant Staphylococcus pseudintermedius in a Veterinary Teaching Hospital.
J Clin Microbiol. 45:1118-1125. 2007
16Tabe, Y. Jin L, Tsutsumi-Ishii Y, Xu Y, McQueen T, Priebe W, Mills GB, Ohsaka A, Nagaoka I, Andreeff M, Konopleva M.
Activation of Integrin-Linked Kinase Is a Critical Prosurvival Pathway Induced in Leukemic Cells by Bone Marrow-Derived Stromal Cells.
Cancer Res. 67:684-694, 2007
17Tamura T, Kobayashi H, Yamataka A, Lane GJ, Koga H, Miyano T.
Inchin-ko-to prevents medium-term liver fibrosis in postoperative biliary atresia patients.
Pediatr Surg Int. Apr;23(4):343-7. 2007
18Tsuchihashi, H., T. Hasegawa, K. Sumiyoshi, H. Ogawa, S. Ikeda, T. Ando, A. Nakao, and K. Okumura.
TWEAK inhibits TGF-beta-induced contraction of normal and keloid fibroblast-embedded collagen gel.
J Dermatol Sci 45:216-218. 2007
19Wang C, Shoji H, Sato H, Nagata S, Ohtsuka Y, Shimizu T, Yamashiro Y.
Effects of oral administration of Bifidobacterium breve on fecal lactic acidand short-chain fatty acids in low-birth-weight infants.
J Pediatr Gastro Hepato Nutri, 44: 252-7, 2007
20Watanabe S, Ito T, Morimoto Y, Takeuchi F, Hiramatsu K.
Precise excision and self-integration of a composite transposon as a model for spontaneous large-scale chromosome inversion/deletion of the Staphylococcus haemolyticus clinical strain JCSC1435.
J Bacteriol. 189:2921-2925. 2007

英文原著(2006年)

1Bae T, Baba T, Hiramatsu K, Schneewind O.
Prophages of Staphylococcus aureus Newman and their contribution to virulence.
Mol Microbiol 62:1035-1047. 2006
2Chen X, Niyonsaba F, Ushio H, Nagaoka I, Ikeda S, Okumura K, Ogawa H.
Human cathelicidin LL-37 increases vascular permeability in the skin via mast cell activation, and phosphorylates MAP kinase p38 and ERK in mast cells.
J Dermatol Sci. 43: 63-6, 2006.
3Cheuk, A. T., L. Chan, B. Czepulkowski, S. A. Berger, H. Yagita, K. Okumura, F. Farzaneh, G. J. Mufti, and B. A. Guinn.
Development of a whole cell vaccine for acute myeloid leukaemia.
Cancer Immunol Immunother 55:68-75. 2006
4Chongtrakool P, Ito T, Ma XX, Kondo Y, Trakulsomboon S, Tiensasitorn C, Jamklang M, Chavalit T, Song JH, Hiramatsu K
Staphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries: a proposal for a new nomenclature for SCCmec elements.
Antimicrob Agents Chemother 50:1001-1012, 2006.
5Cui L, Iwamoto A, Lian J-Q, Neoh Hui-min, Maruyama T, Horikawa Y and Hiramatsu K.
Novel Mechanism of Antibiotic Resistance Originating in Vancomycin-Intermediate Staphylococcus aureus.
Antimicrob Agents Chemother 50:428-38, 2006
6Cui L, Tominaga E, Neoh Hui-min, and Hiramatsu K.
Correlation between Reduced Daptomycin Susceptibility and Vancomycin. Resistance in Vancomycin-Intermediate Staphylococcus aureus.
Antimicrob Agents Chemother 50:1079-1082, 2006
7Fan P, Gao T, Li M, Liao W, Fu M, Liu Y and Ikeda S.
A case of impetigo herpetiformis associated with intrahepatic cholestasis of pregnancy.
J Dermatol. 33: 563-6, 2006.
8Fujii T, Iida Y, Yomogida M, Ikeda K, Haga T, Jikumaru Y, Ninami M, Nishimura N, Kodera Y, Inada Y, Shirai T, Hirose S, and Nishimura H.
Genetic control of the spontaneous activation of CD4+ Th cells in systemic lupus erythematosus-prone (NZB x NZW) F1 mice.
Genes Immun. 7:647-654, 2006.
9Fujii T, Ohtsuka Y, Lee T, Kudo T, Shoji H, Sato H, Nagata S, Shimizu T, Yamashiro Y.
Bifidobacterium breve enhances TGF-b signaling by regulatingSMAD7 expression in preterm infants.
J Pediatr Gastroenterol Nutr 43: 83-8, 2006
10Hamano Y, Tsukamoto K, Abe M, Sun G, D, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Ogawara A, Tachikawa H, Nishimura H, Tokunaga K, Hirose S, and Suzuki K.
Genetic dissection of vasculitis, myeloperoxidase-specific antineutrophil cytoplasmic autoantibody production, and renal traits in spontaneous crescentic glomerulonephritis-forming/Kinjo mice.
J. Immunol. 176:3662-3673, 2006.
11Haruna K, Shiraki Y, Hiruma M, Ikeda S, Kawasaki M.
A case of lymphangitic sporotrichosis occurring on both forearms with a published work review of cases of bilateral sporotrichosis in Japan.
J Dermatol. 33: 364-7, 2006.
12Hasegawa T, Matsukura T, Mizuno Y, Suga Y, Ogawa H and Ikeda S.
Clinical trial of a laser device called fractional photothermolysis system for acne scars.
J Dermatol. 33:623-7, 2006.
13Hayashi Y, Yamataka A, Kaneyama K, Kato Y, Yanai T, Kobayashi H, Lane GJ, Miyano T.
Review of 86 myelodysplasia patients with neurogenic bladder who had sigmoidocolocystoplasty followed-up for more than 10 years.
J Urol 176:1806-1809, 2006
14Hirose S, Jiang Y, Nishimura H, and Shirai T.
Significance of MHC class II haplotypesand IgG Fc receptors in SLE.
Springer Seminars in Immnopathol. 28:163-174, 2006.
15Hori, J., M. Wang, M. Miyashita, K. Tanemoto, H. Takahashi, T. Takemori, K. Okumura, H. Yagita, and M. Azuma.
B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts.
J Immunol 177:5928-5935. 2006
16Hua, J. et al.:
Inhibitory effects of oral glucosamine administration on platelet activation in guinea pigs.
Inflamm. Regener. 26: 446-452, 2006.
17Iizumi K, Mikami Y, Hashimoto M, Nara T, Hara Y, Aoki T.
Molecular cloning and characterization of ouabain-insensitive Na+-ATPase in the parasitic Protist, Trypanosoma cruzi.
Biochim Biophys Acta-Biomembranes , 1758, 738-746. 2006
18Inukai, T., X. Zhang, M. Goto, K. Hirose, K. Uno, K. Akahane, A. Nemoto, K. Goi, H. Sato, K. Takahashi, H. Honna, K. Kagami, K. Nakamoto, H. Yagita, K. Okumura, T. Koyama-Okazaki, S. Nakazawa, and K. Sugita.
Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand: a possible mechanism for poor sensitivity to antitumor immunity.
Leukemia 20:2119-2129. 2006
19Kamata, K., S. Kamijo, A. Nakajima, A. Koyanagi, H. Kurosawa, H. Yagita, and K. Okumura.
Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis.
J Immunol 177:6433-6439. 2006
20Kamijo, S., A. Nakajima, K. Ikeda, K. Aoki, K. Ohya, H. Akiba, H. Yagita, and K. Okumura.
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody.
Biochem Biophys Res Commun 347:124-132. 2006
21Kanai, T., K. Uraushihara, T. Totsuka, Y. Nemoto, R. Fujii, T. Kawamura, S. Makita, D. Sawada, H. Yagita, K. Okumura, and M. Watanabe.
Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis.
J Gastroenterol Hepatol 21:1136-1142. 2006
22Kato Y, Yamtaka A, Okazaki T, Yanai T, Lane GJ, Kobayashi H, Miyano T.
Surgical treatment and outcomeof mega-hydronephrosis due to pelviuteric jundotion stenosis.
Pediatr Surg Int 22: 911-913, 2006
23Kikuchi, Y., T. Takai, M. Ota, T. Kato, K. Takeda, K. Mitsuishi, S. Ikeda, K. Okumura, and H. Ogawa.
Application of immunoreaction enhancer solutions to an enzyme-linked immunosorbent assay for antigen-specific IgE in mice immunized with recombinant major mite allergens or ovalbumin.
Int Arch Allergy Immunol 141:322-330. 2006
24Kikuchi, Y., T. Takai, T. Kuhara, M. Ota, T. Kato, H. Hatanaka, S. Ichikawa, T. Tokura, H. Akiba, K. Mitsuishi, S. Ikeda, K. Okumura, and H. Ogawa.
Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses.
J Immunol 177:1609-1617. 2006
25Komatsu N, Suga Y, Saijoh K, Liu AC, Khan S, Mizuno Y, Ikeda S, Wu HK, Jayakumar A, Clayman GL, Shirasaki F, Takehara K, Diamandis EP.
Elevated human tissue kallikrein levels in the stratum corneum and serum of peeling skin syndrome-type B patients suggests an over-desquamation of corneocytes.
J Invest Dermatol. 126:2338-42, 2006.
26Nakano N, Shiraki Y, Hiruma M, Ikeda S, Sugita T.
A Chinese-Japanese boy with black dot ringworm due to Trichophyton violaceum.
J Dermatol. 33: 165-8, 2006.
27Lin Q, Xiu Y, Jiang Y, Tsurui H, Nakamura K, Kodera S, Ohtsuji M, Ohtsuji N, Shiroiwa W, Tsukamoto K, Amano H, Amano E, Kinoshita K, Sudo K, Nishimura H, Izui S, Shirai T, and Hirose S.
Genetic Dissection of the Effects of Stimulatory and Inhibitory IgG Fc Receptors on Murine Lupus.
J. Immunol. 177:1646-1654, 2006.
28Ma XX, Ito T, Chongtrakool P, Hiramatsu K.
Molecular epidemiology of Japanese hospital MRSA 1979-85. -Predominance of Panton-Valentine leukocidin positive clones.
J Clin Microbiol 44:4515-4527. 2006
29Maeda, K., C. Nishiyama, T. Tokura, H. Nakano, S. Kanada, M. Nishiyama, K. Okumura, and H. Ogawa.
FOG-1 represses GATA-1-dependent FcepsilonRI beta-chain transcription: transcriptional mechanism of mast-cell-specific gene expression in mice.
Blood 108:262-269. 2006
30Mizuno Y, Suga Y, Haruna K, Muramatsu S, Hasegawa T, Kohroh K, Shimizu T, Komatsu N, Ogawa H and Ikeda S.
A case of Japanese neonate with congenital ichthyosiform erythroderma diagnosed as Netherton syndrome.
Clin Exp Dermatol. 31: 677-80, 2006.
31Mizuno Y, Suga Y, Hasegawa T, Haruna K, Kohroh K, Ogawa H, Ikeda S, Shimizu T, Komatsu N.
A case of peeling skin syndrome successfully treated with topical calcipotriol.
J Dermatol. 33:430-2, 2006.
32Nagaoka, I. Tamura H, Hirata M.
An antimicrobial cathelicidin peptide, human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPRL1 and P2X7.
J. Immunol. 176: 3044-52, 2006
33Nakajima, A., S. Komazawa-Sakon, M. Takekawa, T. Sasazuki, W. C. Yeh, H. Yagita, K. Okumura, and H. Nakano.
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
Embo J 25:5549-5559. 2006
34Nakamura K, Sugawara Y, Sawabe K. Ohashi A, Tsurui H, Xiu Y, Ohtsuji M, Lim Q, Nishimura H, Hasegawa H, and Hirose S.
Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.
J. Neuroscience 26:530-534, 2006.
35Nakamura T, Sekigawa I, Ogasawara H, Mitsuishi K, Hira K, Ikeda S, Ogawa H.
Expression of DNMT-1 in patients with atopic dermatisis.
Arch Dermatol Res. 298: 253-6, 2006.
36Nakamura, T., Y. Hirasawa, T. Takai, K. Mitsuishi, M. Okuda, T. Kato, K. Okumura, S. Ikeda, and H. Ogawa.
Reduction of skin barrier function by proteolytic activity of a recombinant house dust mite major allergen Der f 1.
J Invest Dermatol 126:2719-2723. 2006
37Nakano N, Hiruma M, Shiraki Y, Chen X, Porgpermdee S and Ikeda S.
Combination of pulse therapy with terbinafine tablets and topical terbinafine cream for the treatment of dermatophyte onchomycosis: a pilot study.
J Dermatol. 33: 753-8, 2006.
38Ochiai T, Nishimura K, Noguchi H, Kitajima M, Tsuruoka Y, Takahashi Y, Tsukada A, Watanabe E, Nagaoka I, Futagawa S.
Prognostic impact of orotate phosphoribosyl transferase activity in resectable colorectal cancers treated by 5-fluorouracil-based adjuvant chemotherapy.
J. Surg. Oncol. 94: 45-50, 2006.
39Ochiai, T. Nishimura K, Noguchi H, Kitajima M, Tsukada A, Watanabe E, Nagaoka I, Futagawa S.
Prognostic impact of orotate phosphoribosyl transferase among 5-fluorouracil metabolic enzymes in resectable colorectal cancers treated by oral 5-fluorouracil-based adjuvant chemotherapy.
Int. J. Cancer 118: 3084-3088, 2006.
40Oikawa, T., Y. Kamimura, H. Akiba, H. Yagita, K. Okumura, H. Takahashi, M. Zeniya, H. Tajiri, and M. Azuma.
Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease.
J Immunol 177:4281-4287. 2006
41Okuda, D. Yomogida S, Tamura H, Nagaoka I.
Determination of the antibacterial and LPS-neutralizing regions of guinea pig neutrophil cathelicidin peptide CAP11.
Antimicrob. Agents Chemother. 50, 2602-2607, 2006.
42Ota, A. Yonemoto H, Someya A, Itoh S, Kinoshita K, Nagaoka I.
Changes in matrix metalloproteinase 2 activities in amniochorions during premature rupture of membranes.
J. Soc. Gynecol. Investig. 13: 592-597, 2006.
43Porgpermdee S, Takagi A, Mayuzumi N, Ogawa H, Ikeda S, Nakamura S.
Expression of SERCA2 (Darier's disease gene product) in acantholytic dermatoses.
J Dermatol Sci. 43: 146-9, 2006
44Sariego I, Annoura T, Nara T, Hashimoto M, Tsubouchi A, Iizumi K, Makiuchi T, Murata E, Kita K, Aoki T
Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase isoforms.
Parasitol Int , 55, 11-16. 2006
45Sato, T. Iwabuchi K, Nagaoka I, Adachi Y, Ohno N, Tamura H, Seyama K, Fukuchi Y, Nakayama H, Yoshizaki F, Takamori K, Ogawa H.
Induction of human neutrophil chemotaxis by Candida albicans-derived beta-1,6-long glycoside side-chain-branched beta-glucan.
J. Leukoc. Biol. 80: 204-211, 2006.
46Shirai T and Hirose S.
Molecular pathogenesis of SLE.
Springer Seminars in Immunopathol. 28:79-82, 2006.
47Shiraki Y, Hiruma M, Hirose N, Sugita T and Ikeda S.
A nationwide survey of Trichophyton tonsurans infection among combat sport club members in Japan using a guestionnaire form and the hairbrush method.
J Am Acad Dermatol. 54: 622-6, 2006.
48Shiraki Y, Hiruma M, Kano R, Miyamoto C and Ikeda S.
Case of tinea capitis caused by Trichophyton mentagrophytes (molecular type Arthroderma benhamiae): prevalence of a new zoonotic fungal infection in Japan.
J Dermatol. 33: 504-6, 2006.
49Shiraki Y, Hiruma M, Matsuba Y, Kano R, Makimura K, Ikeda S, Ogawa H.
A case of tinea corporis caused by Arthroderma benhamiae (teleomorph of Tinea mentagrophytes) in a pet shop employee.
J Am Acad Dermatol. 55: 153-4, 2006.
50Shiraki Y, Ishibashi Y, Hiruma M, Nishikawa A and Ikeda S.
Cytekine secretion profiles of human keratinocytes during Trichophyton tonsurans and Arthroderma benhamiae infections.
J Med Microbiol. 55: 1175-85, 2006.
51Shiroiwa W, Tsukamoto K, Ohtsuji M, Lin Q, Ida A, Kodera S, Ohtsuji Nishimura H, Tsurui H, Kinoshita K, Nishimura H, Shirai T, and Hirose S.
IL-4Ra polymorphism in regulation of IL-4 synthesis by T cells: implication in susceptibility to a subset of murine lupus.
Int. Immunol. 19:175-183, 2006.
52Someya, A. Moss J, Nagaoka I.
Involvement of a guanine nucleotide-exchange protein, ARF-GEP1 0 0/BRAG2a in the apoptotic cell death of monocytic phagocytes.
J. Leukoc. Biol. 80: 915-921, 2006.
53Tabe, Y. Konopleva M, Kondo Y, Contractor R, Jin L, Ruvolo V, Tsutsumi-Ishii Y, Miyake K, Miyake N, Ohsaka A, Nagaoka I, Issa JP, Andreeff M.
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter. Ann.
Hematol. 85: 689-704, 2006.
54Tabe, Y. Konopleva M, Contractor R, Munsell M, Schober WD, Jin L, Tsutsumi-Ishii Y, Nagaoka I, Igari J, Andreeff M.
Upregulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells.
Blood. 107: 1546-1554, 2006.
55Takagi A, Nishiyama C, Kanada S, Niwa Y, Fukuyama K, Ikeda S, Okumura K, Ogawa H.
Prolonged MHC class II expression and CIITA transcription in human keratinocytes.
Biochem Biophys Res Commun. 25: 388-93, 2006.
56Takagi, A., C. Nishiyama, S. Kanada, Y. Niwa, K. Fukuyama, S. Ikeda, K. Okumura, and H. Ogawa.
Prolonged MHC class II expression and CIITA transcription in human keratinocytes.
Biochem Biophys Res Commun 347:388-393. 2006
57Takai, T., E. Mizuuchi, Y. Kikuchi, T. Nagamune, K. Okumura, and H. Ogawa.
Glycosylation of recombinant proforms of major house dust mite allergens Der p 1 and Der f 1 decelerates the speed of maturation.
Int Arch Allergy Immunol 139:181-187. 2006
58Uno, T., K. Takeda, Y. Kojima, H. Yoshizawa, H. Akiba, R. S. Mittler, F. Gejyo, K. Okumura, H. Yagita, and M. J. Smyth.
Eradication of established tumors in mice by a combination antibody-based therapy.
Nat Med 12:693-698. 2006
59Usui, Y., H. Akiba, M. Takeuchi, T. Kezuka, A. Takeuchi, T. Hattori, Y. Okunuki, T. Yamazaki, H. Yagita, M. Usui, and K. Okumura.
The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis.
Eur J Immunol 36:3071-3081. 2006
60Yomogida, S. et al.
Effect of glucosamine on interleukin-8 production from human colonic epithelial cell cline.
Inflamm. Regener. 26: 513-518, 2006.

英文原著(2005年)

1Akiba, H., K. Takeda, Y. Kojima, Y. Usui, N. Harada, T. Yamazaki, J. Ma, K. Tezuka, H. Yagita, and K. Okumura. 2005.
The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.
J Immunol 175:2340-2348
2Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T.
The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anae robic, parasitic conditions.
J Mol Evol, 60, 113-127, 2005
3Aramaki, O., F. Inoue, T. Takayama, M. Shimazu, M. Kitajima, Y. Ikeda, K. Okumura, H. Yagita, N. Shirasugi, and M. Niimi. 2005.
Interleukin-10 but not transforming growth factor-? is essential for generation and suppressor function of regulatory cells induced by intratracheal delivery of alloantigen.
Transplantation 79:568-576.
4Aramaki, O., F. Inoue, T. Takayama, M. Shimazu, M. Kitajima, Y. Ikeda, K. Okumura, H. Yagita, N. Shirasugi, and M. Niimi. 2005.
Various costimulatory pathways are essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplant Proc 37:1934-1936.
5Bashuda, H., M. Kimikawa, K. Seino, Y. Kato, F. Ono, A. Shimizu, H. Yagita, S. Teraoka, and K. Okumura. 2005.
Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates.
J Clin Invest 115:1896-1902.
6Boyce JM, Cookson B, Christiansen K, Hori S, Vuopio-Varkila J, Kocagoz S, Oztop AY,
Vandenbroucke-Grauls CM, Harbarth S, Pittet D. Meticillin-resistant Staphylococcus aureus.
Lancet Infect Dis 5:653-63, 2005
7Chen X, Niyonsaba F, Ushio H, Okuda D, Nagaoka I, Ikeda S, Okumura K, Ogawa H.
Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli.
J. Dermatol. Sci. 40: 123-132, 2005
8Cui L, Lian JQ, Neoh HM, Reyes E, Hiramatsu K.
DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.
Antimicrob Agents Chemother 49:3404-13,2005
9Fukumoto K, Nagaoka I, Yamataka A, Kobayashi H, Yanai T, kato Y, Miyano T.
Effect of antibacterial cathelicidin peptiden CAP18/LL-37 on sepsis in neonatal rats.
Pediatr Surg Int. 2005 Jan;21(1):20-4.
10Hasegawa T, Suga Y, Mizoguchi M, Muramatsu S, Mizuno Y, Ogawa H, Kubo K, Kuroyanagi Y.
An allogeneic cultured dermal substitute suitable for treating intractable skin ulcers and large skin defects prior to autologous skin grafting: three case reports.
J Dermatol 32:715-20, 2005
11Hashimoto M, N.-Shimada J, Aoki T.
Trypanosoma cruzi post-transcri ptionally upregulates and exploits cellular FLIP for inhibition of death-inducing signal.
Mol Biol Cell, 16, 3521-3528, 2005
12Hashimoto M, Nakajima-Shimada J, Ishidoh K, Aoki T.
Gene expression profiles in response to Fas stimulation in Trypanosoma cruzi-infected host cells.
Int J Parasitol, 35, 1587-1594, 2005
13Heissig, B., S. Rafii, H. Akiyama, Y. Ohki, Y. Sato, T. Rafael, Z. Zhu, D. J. Hicklin, K. Okumura, H. Ogawa, Z. Werb, and K. Hattori. 2005.
Lowdose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization.
J Exp Med 202:739-750.
14Hisata K, Kuwahara-Arai K, Yamanoto M, Ito T, Nakatomi Y, Cui L, Baba T, Terasawa M, Sotozono C, Kinoshita S, Yamashiro Y, Hiramatsu K.
Dissemination of methicillin-resistant staphylococci among healthy Japanese children.
J Clin Microbiol Jul;43(7):3364-72 2005
15Hua J, Suguro S, Hirano S, Sakamoto K, Nagaoka I.
Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats.
Inflamm. Res. 54: 127-132, 2005
16Inaoka DK, Takashima E, Osanai A, Shimizu H, Nara T, Aoki T, Harada S, Kita K.
Expression, purification and crystallization of Trypa nosoma cruzi dihydroorotate dehydrogenase complexed with orotate.
Acta Cryst, F61, 875-878, 2005
17Ishihara M, Yamataka A, Kaneyama K, Koga H, Kobayashi H, Lane GJ, Miyano T,
Prospective analysis of primary modified Georgeson's laparoscopy-assisted endorectal pull-through for Hirschsprung's disease: short- to mid-term results.
Pediatr Surg Int 21: 878-882, 2005
18Ito, T., C. Nishiyama, M. Nishiyama, H. Matsuda, K. Maeda, Y. Akizawa, R. Tsuboi, K. Okumura, and H. Ogawa.
Mast cells acquire monocyte-specific gene expression and monocyte-like morphology by overproduction of PU.1.
J Immunol 174:376-383, 2005.
19Kaduka, Y., K. Takeda, M. Nakayama, K. Kinoshita, H. Yagita, and K. Okumura.
TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.
Biochem Biophys Res Commun 331:384-390 2005.
20Kanamaru, Y., K. Sumiyoshi, H. Ushio, H. Ogawa, K. Okumura, and A. Nakao.
Smad3 deficiency in mast cells provides efficient host protection against acute septic peritonitis.
J Immunol 174:4193-4197. 2005.
21Kaneda, H., K. Takeda, T. Ota, Y. Kaduka, H. Akiba, Y. Ikarashi, H. Wakasugi, M. Kronenberg, K. Kinoshita, H. Yagita, and K. Okumura.
ICOS costimulates invariant NKT cell activation.
Biochem Biophys Res Commun 327:201-207. 2005.
22Kato, T., T. Takai, K. Mitsuishi, K. Okumura, and H. Ogawa. 2005.
Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases.
J Allergy Clin Immunol 116:169-176. 2005
23Kawada, H., C. Nishiyama, A. Takagi, T. Tokura, N. Nakano, K. Maeda, N. Mayuzumi, S. Ikeda, K. Okumura, and H. Ogawa.
Transcriptional regulation of ATP2C1 gene by Sp1 and YY1 and reduced function of its promoter in Hailey-Hailey disease keratinocytes.
J Invest Dermatol 124:1206-1214, 2005
24Kawamura, H., H. Yagita, T. Nisizawa, N. Izumi, C. Miyaji, R. E. Vance, D. H. Raulet, K. Okumura, and T. Abo.
Amelioration of acute graftversus-host disease by NKG2A engagement on donor T cells.
Eur J Immunol 35:2358-2366. 2005.
25Koga H, Yamataka A, Kobayashi H, Lane GJ, Miyano T,
Median sternotomy provides excellent exposure for excising anterior mediastinal tumors in children.
Pediatr Surg Int 21: 864-867, 2005
26Lu-Suguro JF, Hua J, Sakamoto K, Nagaoka I.
Inhibitory action of glucosamine on platelet activation in guinea pigs.
Inflamm. Res. 54:493-499 2005
27Ma XX, Galiana A, Pedreira W, Mowszowicz M, Christophersen I, Machiavello S, Lope L, Benaderet S, Buela F, Vincentino W, Albini M, Bertaux O, Constenla I, Bagnulo H, Llosa L, Ito T, Hiramatsu K.
Community-acquired methicillin-resistant Staphylococcus aureus, Uruguay.
Emerg Infect Dis. 11(6):973-6 2005
28Mayuzumi N, Ikeda S, Kawada H, Fan PS, Ogawa H.
Effects of UVB irradiation, pro-inflammatory cytokines and raised extracellular calcium concentration on the expression of ATP2A2 and ATP2C1.
Br J Dermatol. 2005 Apr;152(4):697-701.
29Mayuzumi N, Ikeda S, Kawada H, Ogawa H.
Effects of drugs and anticytokine antibodies on expression of ATP2A2 and ATP2C1 in cultured normal human keratinocytes.
Br J Dermatol. 2005 May;152(5):920-4.
30Mehmut M, Takeda K, Abe M., Ogara H, Hirose S, Okumura K, Fujime M.
Fas ligand and TNF-related apoptosis-inducing ligand induction on infiltrating lymphocytes in bladder carcinoma by bacillus Calmette-Guerin treatment.
Urol Int, 75:80-87, 2005
31Miyahira, Y., Y. Takashima, S. Kobayashi, Y. Matsumoto, T. Takeuchi, M. Ohyanagi-Hara, A. Yoshida, A. Ohwada, H. Akiba, H. Yagita, K. Okumura, and H. Ogawa.
Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection.
Infect Immun 73:7356-7365, 2005
32Nagaoka I, Kuwahara-Arai K, Tamura H, Hiramatsu K, Hirata M.
Augmentation of the bactericidal activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by amino acid substitutions.
Inflamm. Res. 54: 66-73, 2005.
33Nakamura K, Nishimura H, Hirose S.
Correlation of aggression with serum IgM level in autoimmune-prone NZB mice.
Developmental Brain Res earch, 159:145-148, 2005.
34Nakano, N., A. Nakao, K. Ishidoh, R. Tsuboi, E. Kominami, K. Okumura, and H. Ogawa. 2005.
CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes.
Br J Dermatol 153:37-45.
35Nakano, N., A. Nakao, T. Uchida, N. Shirasaka, H. Yoshizumi, K. Okumura, R. Tsuboi, and H. Ogawa. 2005.
Effects of arachidonic acid analogs on Fc epsilon RI-mediated activation of mast cells.
Biochim Biophys Acta 1738:19-28.
36Nakano, N., C. Nishiyama, N. Masuoka, M. Nishiyama, H. Yamane, K. Okumura, and H. Ogawa. 2005.
Analysis of PU.1/ICSBP (IRF-8) complex formation with various PU.1 mutants: molecular cloning of rat Icsbp (Irf-8) cDNA.
Immunogenetics 56:871-877.
37Nakazawa, T., T. Takai, H. Hatanaka, E. Mizuuchi, T. Nagamune, K. Okumura, and H. Ogawa. 2005.
Multiple-mutation at a potential ligand-binding region decreased allergenicity of a mite allergen Der f 2 without disrupting global structure.
FEBS Lett 579:1988-1994.
38Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Iizumi K, Dohmo to Y, Ono T, Aoki T.
Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase activity and on the protozoan growth in mammalian cells.
Parasitol Int,54, 59-64, 2005
39Nishiyama, C., T. Ito, M. Nishiyama, S. Masaki, K. Maeda, N. Nakano, W. Ng, K. Fukuyama, M. Yamamoto, K. Okumura, and H. Ogawa.
GATA-1 is required for expression of Fc? RI on mast cells: analysis of mast cells derived from GATA-1 knockdown mouse bone marrow.
Int Immunol 17:847-856, 2005.
40Niyonsaba F, Ushio H, Nagaoka I, Okumura K, Ogawa H.
The human beta -defensins (-1, -2, -3, -4) and cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK activation in primary human keratinocytes.
J. Immunol. 175: 1776-1784, 2005
41Noguchi N, Suwa J, Narui K, Sasatsu M, Ito T, Hiramatsu K, Song JH.
Susceptibilities to antiseptic agents and distribution of antiseptic-resistance genes qacA/B and smr of methicillin-resistant Staphylococcus aureus isolated in Asia during 1998 and 1999.
J Med Microbiol 54(:557-65,2005
42Ogata M, Tutumimoto Sato K, Kunikane T, Oka K, Seki M, Urano S, Hiramatsu K, Endo T.
Antibacterial activity of dipropofol and related compounds.
Biol Pharm Bull 28:1120-2, 2005
43Okamoto, A., T. Kawamura, K. Kanbe, Y. Kanamaru, H. Ogawa, K. Okumura, and A. Nakao. 2005.
Suppression of serum IgE response and systemic anaphylaxis in a food allergy model by orally administered high-dose TGF-beta.
Int Immunol 17:705-712.
44Ota, T., K. Takeda, H. Akiba, Y. Hayakawa, K. Ogasawara, Y. Ikarashi, S. Miyake, H. Wakasugi, T. Yamamura, M. Kronenberg, D. H. Raulet, K. Kinoshita, H. Yagita, M. J. Smyth, and K. Okumura.
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.
Blood 106:184-192. 2005.
45Qi Z, Wang J, Sun Z, Ma F, Zhang Q, Hirose S, Jiang Y.
Polymorphism of the mouse gene for the interleukin 10 receptor alpha chain (Il10 ra) and its association with the autoimmune phenotype.
Immunogenetics. 57:697-702, 2005.
46Sampanthanarak P, Niyonsaba F, Ushio H, Nagaoka I, Ikeda S, Okumura, K, Ogawa H.
The effect of antibacterial peptide human beta-defensin-2 on interleukin-18 secretion by keratinocytes.
J. Dermatol. Sci. 37:188-191, 2005
47Sanmano B, Mizoguchi M, Suga Y, Ikeda S, Ogawa H.
Engraftment of umbilical cord epithelial cells in athymic mice: in an attempt to improve reconstructed skin equivalents used as epithelial composite.
J Dermatol Sci. 2005 Jan;37(1):29-39.
48Shike T, Gohda T, Tanimoto M, Kobayashi M, Makita Y, Funabiki K, Horikoshi, Hirose S, Shirai T, Tomino Y.
Chromosomal mapping of a quantitative trait locus for the development of albuminuria in diabetic KK/Ta mice.
Nephrol Dial Transplant, 20:879-885, 2005
49Sng LH, Koh TH, Wang GC, Hsu LY, Kapi M, Hiramatsu K.
Heterogeneous vancomy cin-resistant Staphylococcus aureus (hetero-VISA) in Singapore.
Int J Antimicrob Agents. Feb;25(2):177-9. 2005
50Soo Ko K, Peck KR, Sup Oh W, Lee NY, Hiramatsu K, Song JH.
Genetic differentiation of methicillin-resistant Staphylococcus aureus strains from Korea and Japan.
Microb Drug Resist 11:279-86, 2005
51Suzuki H, Suzuki Y, Yamanaka T, Hirose S, Nishimura H, Toei J, Horikoshi S, Tomino Y.
Genome-wide scan in novel IgA nephropathy model identifies susceptibility locus on murine chromosome 10, in a region sytenic to human IGAN1 on chromosome 6q22-23.
J Am Soc Nephrol, 16:1289-1299, 2005
52Tabe Y, Konopleva M, Contractor R, Munsell M, Schober WD, Jin L, Tsutsumi-Ishii Y, Nagaoka I, Igari J, Andreeff M.
Upregulation of MDR and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells.
Blood. 2006 Feb 15;107(4):1546-54. Epub 2005 Oct 13.
53Takai, T., M. Takaoka, H. Yasueda, K. Okumura, and H. Ogawa. 2005.
Dilution method to refold bacterially expressed recombinant Der f 2 and Der p2 to exhibit the secondary structure and histamine-releasing activity of natural allergens.
Int Arch Allergy Immunol 137:1-8.
54Takai, T., T. Kato, H. Yasueda, K. Okumura, and H. Ogawa.
Analysis of the structure and allergenicity of recombinant pro- and mature Der p1 and Der f 1: major conformational IgE epitopes blocked by prodomains.
J Allergy Clin Immunol 115:555-563. 2005.
55Takai, T., T. Kato, M. Ota, H. Yasueda, T. Kuhara, K. Okumura, and H. Ogawa.
Recombinant Der p 1 and Der f 1 with in vitro enzymatic activity to cleave human CD23, CD25 and alpha1-antitrypsin, and in vivo IgE-eliciting activity in mice.
Int Arch Allergy Immunol 137:194-200, 2005.
56Takai, T., T. Kato, Y. Sakata, H. Yasueda, K. Izuhara, K. Okumura, and H. Ogawa.
Recombinant Der p 1 and Der f 1 exhibit cysteine protease activity but no serine protease activity.
Biochem Biophys Res Commun 328:944-952, 2005.
57Takaya N, Katoh Y, Iwabuchi K, Hayashi I, Konishi H, Itoh S, Okumura K, Ra C, Nagaoka I, Daida H.
Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor gamma-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury.
J. Mol. Cell. Cardiol. 39: 856-864, 2005.
58Takeda, K., E. Cretney, Y. Hayakawa, T. Ota, H. Akiba, K. Ogasawara, H. Yagita, K. Kinoshita, K. Okumura, and M. J. Smyth. 2005.
TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.
Blood 105:2082-2089.
59Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K.
Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species.
J Bacteriol 187:7292-308,2005
60Tanaka, T., T. Ebata, A. Tajima, K. Kinoshita, K. Okumura, and H. Yagita.
Beta2-microglobulin required for cell surface expression of blastocyst MHC.
Biochem Biophys Res Commun 332:311-317. 2005
61Tokura, T., N. Nakano, T. Ito, H. Matsuda, Y. Nagasako-Akazome, T. Kanda, M. Ikeda, K. Okumura, H. Ogawa, and C. Nishiyama.
Inhibitory effect of polyphenol-enriched apple extracts on mast cell degranulation in vitro targeting the binding between IgE and Fc epsilon RI.
Biosci Biotechnol Biochem 69:1974-1977. 2005.
62Torun MM, Bahar H, Demirci M, Altas K, Bagdatli Y, Kocazeybek B, Kapi M, Hiramatsu K.
Two heterogeneously vancomycin-intermediate clinical isolates of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in a Turkish university hospital: brief report of asurveillance study.
Int J Antimicrob Agents. Dec;26(6):508-10, 2005
63Totsuka, T., T. Kanai, S. Makita, R. Fujii, Y. Nemoto, S. Oshima, R. Okamoto, A. Koyanagi, H. Akiba, K. Okumura, H. Yagita, and M. Watanabe. 2005.
Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells.
Eur J Immunol 35:1773-1785.
64Tsukahara, R., M. Takeuchi, H. Akiba, T. Kezuka, K. Takeda, Y. Usui, M. Usui, H. Yagita, and K. Okumura. 2005.
Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation.
Int Immunol 17:523-530.
65Uchiyama N, Kabututu Z, Kubata BK, Kiuchi F, Ito M, Nakajima-Shimada J, Aoki T, Ohkubo K, Fukuzumi S, Martin SK, Honda G, Urade Y.
Antichagasic activity of komaroviquinone is due to generation of reactive oxygen species catalyzed by Trypanosoma cruzi old yellow enzyme.
Antimicrob Agents Chemother, 49, 5123-5126, 2005
66Watanabe S, Ito T, Takeuchi F, Endo M, Okuno E, Hiramatsu K.
Structural comparison of ten serotypes of staphylocoagulases in Staphylococcus aureus.
J Bacteriol Jun;187(11):3698-707 2005
67Xue, X., J. H. Piao, A. Nakajima, S. Sakon-Komazawa, Y. Kojima, K. Mori, H. Yagita, K. Okumura, H. Harding, and H. Nakano.
Tumor necrosis factor alpha (TNFalpha ) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS acumulation by TNFalpha.
J Biol Chem 280:33917-33925. 2005
68Yamabe, H., Y. Tanaka, K. Okumura, Y. Morikami, Y. Kimura, Y. Hokamura, and H. Ogawa.
Electrophysiologic characteristics of verapamil-sensitive atrial tachycardia originating from the atrioventricular annulus.
Am J Cardiol 95:1425-1430. 2005
69Yamazaki, T., H. Akiba, A. Koyanagi, M. Azuma, H. Yagita, and K. Okumura.
Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production.
J Immunol 175:1586-1592. 2005
70Zhang B, Ohtsuka Y, Fujii T, Baba H, Okada K, Shoji H, Nagata S, Shimizu T, Yamashiro Y.
Immunological development of preterm infants in early infancy.
Clin Exp Immunol 2005 ;140:92-6.
71Zhang H, Yamataka A, Koga H, Kobayashi H, Lane GL, Miyano T.
Bladder stone formation after sigmoidocolocystoplasty: statistical analysis of risk factors.
J Pediatr Surg 40:407-411, 2005

Communication

1Han, X.; Ito, T.; Uehara, Y.; Zhang, M.; Hiramatsu, K.
Characterization of SCCmec elements that carry ccrA3 and ccrB3 genes identified in Staphylococcus epidermidis.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
2Hiramatsu, K.
Molecular evolution of MRSA and VISA
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
3Lulitanond, A.; Ito, T.; Li, S.; Han, X.; Ma, X. X.; Engchanil, C.; Chanawong, A.; Wilailackana, C.; Jiwakanon, N.; Hiramatsu, K.
Identification of a variant of type IX SCCmec in ST9 MRSA strains isolated in Thailand.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
4Matsuo, M.; Cui, L.; Kim, J.; Hiramatsu, K.
A mutation of cmk (cytidylate kinase) gene confers reduced vancomycin susceptibility in Staphylococcus aureus.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
5Morimoto, Y.; Igarashi, M.; Baba, T.; Hiramatsu, K.
Antimicrobial activity of nybomycin against Escherichia coli.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
6Ishikawa, D.; Osada, T.; Sasaki, T.; Kuwahara-Arai, K.; Haga, K.; Shibuya, T.; Kodani, T.; Hiramatsu, K.; Watanabe, S.
Alterations of Intestinal Microbiota in Ulcerative Colitis Patients Treated with Sequential Antibiotic Combination and Faecal Microbiota Transplantation.
JOURNAL OF CROHNS & COLITIS
7Uehara, Y.; Sasaki, T.; Hiramatsu, K.; Kawada, M.; Furuichi, M.; Imajo, E.; Sato, Y.; Anno, S. T.
ST834 methicillin-resistant Staphylococcus aureus with a pathogenicity island similar to SaPIj50 among children in Saitama, Japan.
Int J Antimicrob Agents.

日本語論文

1桑原京子、平松啓一.
臨床分離株に対するdoripenemの抗菌力.
日本化学療法雑誌 53(S-1)17 – 23 2005
2伊藤輝代、平松啓一.
MRSA感染症.
日本臨床 増刊号 63 Suppl 12, Dec
3小松充孝、田島裕、伊藤輝代、山城佑一郎、平松啓一.
化学発光および呈色試薬を用いたメチシリン耐性黄色ブドウ球菌に対するLinezolidの抗菌活性の評価.
日本化学療法学会雑誌 54:102-110. 2006
4檀原高, 奥村徹, 関谷栄, 内藤俊夫, 堀賢.
インフルエンザで怖い肺炎と脳症 鳥インフルエンザの予防と治療.
順天堂のやさしい医学13かぜとインフルエンザ、順天堂大学医学部編、学生社、東京、115-139, 2006.
5ネオフイミン、堀賢、小松充孝、小栗豊子、竹内史比古、崔龍洙、平松啓一.
バンコマイシン感受性低下がMRSA血流感染症の臨床経過に及ぼす影響の検討.
順天堂医学June ; Vol. (53); 243-250. 2007
6池田恵、堀賢、三澤成毅、小栗豊子、網中 真由美、李澤 康雄、坂田 梢、伊藤 輝代、平松 啓一.
VanB型-バンコマイシン耐性腸球菌による局地的流行伝播の早期発見と拡散防止対策の有効性について.
環境感染 22(3):203-210. 2007
7岡崎千絵、堀賢、森本景子、下嶋和代、佐瀬一洋.
医療従事者における新型インフルエンザワクチン接種後の副反応発生状況.
環境感染 25: 237-241. 2010
8山本典生,中村一哉,浜本いつき,田代眞人.
パンデミックインフルエンザ(H1N1)2009に対するワクチンの評価と新ワクチン開発に向けた展望.
公衆衛生, Aug 74(8):681-686. 2010
9山本典生、田代眞人.
国立感染症研究所インフルエンザウイルス研究センターの紹介.
医学のあゆみ June 232(13): 1230-1232 2010
10冨永英司、伊藤輝代、CHRISTOF VON EIFF、平松啓一.
黄色ブドウ球菌small colony variants出現抑制のためのアルベカシンとスルバクタム/アンピシリンの併用効果.
順天堂医学 56:339-3492010
11茅野崇、菱沼知美、松尾美記、張萠、伊藤輝代、森本ゆふ、平松啓一.
市中獲得型MRSA(CA-MRSA)の高病原性に関する研究:オキサシリン高度耐性化とfudoh領域の影響.
順天堂医学 56:56-67. 2010
12関根美和、馬場理、片山由紀、平松啓一.
黄色ブドウ球菌MHC様分子が貪食などの宿主免疫系に及ぼす影響について.
順天堂医学 57(3), 232-242. 2011
13高橋並子、澤村正之、菊池賢、平松啓一.
多剤耐性淋菌に対するニトロフラントイン,ホスホマイシンを含む代替治療候補としての抗菌薬の感受性.
順天堂医学57(4)365-369. 2011
14小野由可、菊池賢、Xun J、堀賢、平松啓一.
linezolid 治療中に出現した縦隔炎患者由来 methicillin-resistant Staphylococcus aureus のlinezolid 耐性機構.
順天堂医学57(4)370-6. 2011
15金京勲、伊藤輝代、平松啓一.
世界各地で分離されたVancomycin-intermediate S. aureus 46株の分子疫学的解析.
順天堂医学57(5)494-503. 2011
16香本晃良, 崔龍洙、江端望、渡辺由希子、松尾美記、片山由紀、Piyamas Petcharoen、平松啓一.
黄色ブドウ球菌におけるRNAポリメラーゼ遺伝子の突然変異はLinezolidの高感受性化に関連する.
順天堂医学 58(6) 498-505. 2012
17射場敏明, 村井美和, 長岡功, 田部陽子.
敗血症におけるneutrophil extracellular traps (NETs), damage-associated molecular patterns (DAMPs), そして細胞死.
日救急医会誌 24: 181-191 2013.
18細谷志乃、伊藤輝代、三澤成毅、吉池高志、小栗豊子、平松 啓一.
皮膚科外来患者由来 MRSA 株に見られる新規 MRSA クローンの出現状況.
感染症学雑誌 2014 Nov;88(6):840-8.
19三宅幸子.
MAIT細胞と自己免疫.
Jpn J Clin Immunol. 37(1):19-24 2014.
20三宅幸子.
腸内細菌と自己免疫.
Jpn J Clin Immunol. 37(5):398-402 2014.
21三宅幸子.
自然リンパ球.
医学のあゆみ.251(6):479 2014.
22家田健史、桒原京子、森本ゆふ、久末伸一、伊藤輝代、堀江重郎、平松啓一.
尿路感染症主要原因菌のフルオロキノロン系抗菌薬を中心とした薬剤に対する感受性および gyrA・parC における QRDR の遺伝子変異の解析.
日本化学療法学会雑誌 2015. 63(3):343-349
23川合覚, 丹羽孝介, 川瀬三雄, 美田敏宏.
STH-PAS法を活用したマラリア遺伝子診断ツールの開発.
Clinical Parasitology. 26:86-9. 2015.
24三宅幸子.
腸内細菌と自己免疫.
Keynote R・A.,3(1):14-18 2015.
25三宅幸子.
自己免疫疾患と腸内細菌.
Medical Science Digest 41(4):146-149 2015.
26胡忠双, 長岡功.
LPS誘導性ピロトーシスと抗菌ペプチド.
医学のあゆみ253: 1087-1091 2015.
27美田敏宏.
国内で遭遇する可能性のある熱帯病:確実な診断と感染防御の最新知見.
日本臨床内科医会会誌. 29(5):756-60. 2015.
28三宅幸子.
神経免疫. 炎症と免疫.
23(2):105 2015.
29三宅幸子.
自己免疫疾患と腸内細菌.
細胞 47(2):57-60 2015.

著書

1Cui, L., and K. Hiramatsu. 2004.
Vancomycin-resistant Staphylococcus aureus.
in ed, by Franz-Josef Schmitz and Dr. Ad C. Fluit. MRSA. Horizon Scientific Press.
2Kuroda, M., and K. Hiramatsu. 2004.
Genome sequencing and annotation: an overview.
Johnson, A., and Woodford, N., ed., Genomics, Proteomics and Clinical Bacteriology. Humana Press.
3Baba, T.,Takeuchi, F., Kuroda, M., Yuzawa, H., Ito, T., and Hiramatsu, K. 2004.
The Genome of Staphylococcus aureus.
pp In Al'Aladeen, D., and Hiramatsu, K (ed). The Staphylococcus aureus: Molecular and Clinical Aspects. Eliis Harwood, London, UK.
4Hiramatsu, K., Kuroda, M., Baba, T., and K. Okuma. 2004.
Application of Genomic Information to the Diagnosis, Management and Control of Bacterial Infections: The Staphylococcus aureus model.
ed.by D. Persing, et al. Diagnostic Molecular Microbiology 2nd Ed, pp407-418, ASM Press.
5堀 賢.
空気感染対策.
臨床微生物の基礎知識、奥住捷子、小栗豊子編、メディカ出版、東京、215-217, 2006
6堀 賢:
飛沫感染対策.
臨床微生物の基礎知識、奥住捷子、小栗豊子編、メディカ出版、東京、218-220, 2006.
7星最智、堀 賢:
接触感染対策.
臨床微生物の基礎知識、奥住捷子、小栗豊子編、メディカ出版、東京、221-223, 2006.
8堀 賢:
インフルエンザの診断が遅れた場合の治療・管理.
インフルエンザハンドブック、富野康日己、永井厚志編、中外医学社、東京、199-204, 2006
9堀 賢:
順天堂医院での取り組み、わが病院の感染対策.
木村哲編、医薬ジャーナル社、大阪、231-237, 2006.
10山本典生.
細胞培養法による新型インフルエンザワクチン製造におけるバイオセーフティとGMP クリーンテクノロジー
日本工業出版 22:1-5 2012.
11上原由紀.
白血球
感度と特異度からひもとく感染症診療のDecision Making 細川直登編, 文光堂 16-20 (368頁) 2012.
12仁科隆史, 中野裕康.
実験医学増刊号「活性酸素・ガス状分子による恒常性制御と疾患」
山本雅之監修, 赤池孝章, 一條秀憲, 森泰生編 羊土社, 123-129 (219頁) 2012.
13大塚宜一,清水俊明.
周産期診療ワークブック.
日本周産期, 新生児医学会教育, 研修委員会(編) メジカルビュー社,東京.359-361 (461頁) 2012.
14平松啓一.
標準微生物学11.
平松啓一 (監修), 中込 治 (編集), 神谷 茂 (編集), 医学書院 (688頁) 2012.
15山本典生, 田代眞人.
新型インフルエンザ予防接種 Q&A
小児内科 東京医学社 45, 549-551 2013.
16上原由紀.
企画にあたって
臨床感染症ブックレット8巻 感染症の予防や制御に必要なことを実践する. 上原由紀, 前崎繁文, 大曲貴夫編 文光堂 5(168頁) 2013.
17上原由紀.
感染経路別予防策(3)ー接触感染予防策ー
臨床感染症ブックレット8巻 感染症の予防や制御に必要なことを実践する. 上原由紀, 前崎繁文, 大曲貴夫編 文光堂 20-26(168頁) 2013.
18上原由紀.
感染対策の効果を判定するには?
臨床感染症ブックレット8巻 感染症の予防や制御に必要なことを実践する. 上原由紀, 前崎繁文, 大曲貴夫編 文光堂 161-163(168頁) 2013.
19橋本宗明, 奈良武司.
トリパノソーマ症.
別冊感染症症候群(第2版)、上巻 日本臨牀.日本臨牀社、大阪、650-653(812頁) 2013.
20美田敏宏, 北潔.
検査値を読む:寄生虫卵・虫体検査.
内科 111: 1049, 2013 南山堂 2013.
21山本典生, 田代眞人.
細胞培養インフルエンザワクチン
Bio Clinica 北隆館 28: 41-45 2013.
22奈良武司監訳・訳.
Section 17 原虫および蠕虫感染症:概論
Part 8 感染症 ハリソン内科学第4版(原著第18版) 福井次矢、黒川清監修、メディカル・サイエンス・インターナショナル、東京、1465-1470(3376頁) 2013.
23奈良武司監訳・訳.
Section 18 原虫感染症
Part 8 感染症 ハリソン内科学第4版(原著第18版) 福井次矢、黒川清監修、メディカル・サイエンス・インターナショナル、東京、1471-1515(3376頁) 2013.
24奈良武司監訳・訳.
Section 19 蠕虫感染症
Part 8 感染症 ハリソン内科学第4版(原著第18版) 福井次矢、黒川清監修、メディカル・サイエンス・インターナショナル、東京、1516-1542(3376頁) 2013.
25奈良武司.
ヌクレオチド代謝.
岩波生物学辞典第5版 巌佐庸、倉谷滋、斎藤成也、塚谷裕一編、岩波書店、東京(2192頁) 2013.
26Chiba A, Miyake S.
Basic techniques for studies of iNKT cells and MAIT cells.
Arthritis Research Methods and Protocols. Shiozawa S ed. Springer, London, 75-84 2014.
27山田俊幸, 大戸斉, 渥美達也, 三宅幸子, 山内一由編
免疫系のしくみと働き
新版 臨床免疫学第3版. 南江堂 1−25 (340頁) 2014.
28山田俊幸, 大戸斉, 渥美達也, 三宅幸子, 山内一由編
細胞表面分子とサイトカイン
新版 臨床免疫学第3版. 南江堂 1−25 (340頁) 2014.
29胡忠双, 村上泰介, 鈴木香, 田村弘志, 長岡功.
抗菌ペプチドLL-37によるマクロファージ系細胞のピロトーシスの制御.
エンドトキシン・自然免疫研究17 -エンドトキシン・自然免疫の展開:新しい機序、診断、応用. 谷徹, 横地高志 編集, 医学図書出版, 東京, 73-75(105頁) 2014.
30上原由紀.
バンコマイシンとテイコプラニン
“実践的“抗菌薬の選び方・使い方 細川直登編, 医学書院 163−169 (221頁) 2014.
31上原由紀. 胆道感染症
ワンランク上の検査値の読み方・考え方–ルーチン検査から病態変化を見抜く–
本田孝行編, 医学書院 148-153(368頁) 2014.
32美田敏宏.
マラリア/バベシア.
今日の治療指針2014. 医学書院 東京、256-7, (1900頁) 2014.
33渡辺純夫, 永原章仁, 北條麻理子.
消化管疾患
診療マニュアル 日本医学館(692頁) 2014.
34Nakayama H, Iwabuchi K.
Glycosphingolipid-Receptor Interactions in the Innate Immune Responses.
Glycoscience Glycoscience: Biology and Medicine Taniguchi N, Endo T, Hart GW, Seeberger PH, Wong CH. Springer Japan, 699-705 (1568頁) 2015.
35美田敏宏.
特集未来への投資マラリア撲滅へ「薬剤耐性マラリア拡大の解明と対策」
国際人流. 入管協会 340. 12-6, 223-5. 2015.
36山本典生.
今後出現が予想される新型インフルエンザウイルスは?
内科 南江堂116(6), 1087-1090(362頁) 2015.
37鈴木香, 長岡功.
Cathelicidinファミリーの抗菌ペプチドLL-37によるエンドトキシン除去作用.
エンドトキシン・自然免疫研究18 -自然免疫における生体防御ペプチドの多様性. 長岡功,谷徹, 横地高志 編集, 医学図書出版, 東京, 1-6(100頁) 2015.
38胡忠双, 村上泰介, 鈴木香, 田村弘志, 長岡功.
ピロトーシスに対する抗菌ペプチドLL-37の作用.
エンドトキシン・自然免疫研究18 –自然免疫における生体防御ペプチドの多様性. 長岡功,谷徹, 横地高志 編集, 医学図書出版, 東京, 86-88(100頁) 2015.
39多田浩之, 松下健二, 松山考司, 長岡功, 高田春比古.
Porphyromonas gingivalisジンジパインによるヒト歯肉上皮細胞のIL-33誘導を介したCAP18/LL-37ダウンレギュレーション機構.
エンドトキシン・自然免疫研究18 –自然免疫における生体防御ペプチドの多様性. 長岡功,谷徹, 横地高志 編集, 医学図書出版, 東京, 93-97(100頁) 2015.
40森田芙路子, 上原由紀.
予防抗微生物薬
血液腫瘍領域の感染症 原田壮平編, 最新医学社 175-186 (243頁) 2015.
41美田敏宏.
旅行者下痢症とその対策.
改訂版アジア旅行者のための感染症対策.改訂第1版. 連合出版社.29-57. (223頁) 2015.
42奈良武司.
トリパノソーマ症.
別冊骨格筋症候群(第2版)、上巻 日本臨牀、日本臨牀社、大阪、276-280(467頁) 2015.
43美田敏宏.
肺寄生虫症.
EBMを活かす呼吸器診療. 高橋和久, 児玉裕三. メジカルビュー社 223-5 (541頁) 2015.

特許

1特許出願人:学校法人順天堂、生化学工業株式会社
発明者:長岡 功、村上泰介、蓬田 伸、田村弘志
発明の名称:アナンダミド生成抑制
特許出願日:2005年6月16日
特許出願番号:特願2005-176312
2特許出願人:学校法人順天堂、生化学工業株式会社
発明者:長岡 功、平田陸正、田村弘志
発明の名称:アポトーシス抑制剤
特許出願日:2005年11月24日
特許出願番号:特願2005-339395
3特許出願人: 学校法人順天堂、生化学工業株式会社
発明者 : 長岡功、奥田大樹、蓬田 伸、田村弘志
発明の名称 : 抗菌ペプチド
特許出願日 :2005 年7 月5 日
4特許出願人:公益財団法人微生物化学研究会、学校法人順天堂
発明者 : 五十嵐雅之、平松啓一
発明の名称 : 病原性細菌用抗菌剤、及びその用途
特許出願日 :2011年08月24日
特許出願番号:特願2011-182657
5特許出願人:学校法人順天堂
発明者 : 山本典生
発明の名称 : 抗インフルエンザウイルス剤
特許出願日 :2012年08月10日
特許出願番号:特願2012-178250
6特許出願人:学校法人順天堂
発明者 : 平松啓一、森本ゆふ、馬場理
発明の名称 : 抗菌剤
特許出願日 :2013年11月12日
特許出願番号:特願2013-233957
7特許出願人:学校法人順天堂、デンカ生研株式会社
発明者 : 大石 金成、馬場理、平松啓一、中臣康雄.
発明の名称 : 毒素検出方法
特許出願日 :2013年03月21日
特許出願番号:特願2012-265453
8特許出願人:公益財団法人ヒューマンサイエンス振興財団
発明者 : 山本典生、浜本いつき、田代眞人
発明の名称 : 細胞培養組成物、インフルエンザウイルスの生産方法、及び、インフルエンザウイルス
特許出願日 :2013年03月22日
特許出願番号:特願2013-060692
9特許出願人:学校法人順天堂、学校法人早稲田大学、清水建設株式会社
発明者 : 堀賢、森本正一、田辺新一、町田晃一、杉山靖尚、山口一、辻裕次
発明の名称 : 空調システム
特許出願日 :2013年05月10日
特許出願番号:特願2013-100533
10特許出願人:全薬工業株式会社、学校法人順天堂
発明者 : 大澤弘宜、榎並淳平、平松啓一
発明の名称 : 抗ブドウ球菌抗体、その製造方法並びにその使用
特許出願日 :2014年3月11日
特許出願番号:特願2013049268
11特許出願人:学校法人順天堂、国立研究開発法人国立精神・神経医療研究センター、国立大学法 人東京大学、学校法人麻布獣医学園
発明者:三宅幸子, 山村隆, 服部正平, 森田英利
自己免疫疾患の診断方法、自己免疫疾患の診断用バイオマーカー、及び自己免疫疾患の予防又は治療剤
特許出願日:2015年8月27日
特願2015-167839
12特許出願人:国立大学法人千葉大学、学校法人順天堂
発明者:柳田浩志、星野忠次、山本典生
インフルエンザウイルス感染症の予防および/または治療剤
特許公開日:2015年6月26日
特許5765650号