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学校法人順天堂@juntendo1838
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学校法人順天堂@juntendo
スポーツ健康科学部@juntendo.sakura
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スポーツ健康科学部juntendo_sakura
研究活動Research Activities

老人性疾患病態・治療研究センター

研究業績データ

主な研究業績(2017年)

1Yoshino H, Hirano M, Stoessl AJ, Imamichi Y, Ikeda A, Li Y, Funayama M, Yamada I, Nakamura Y, Sossi V, Farrer MJ, Nishioka K, Hattori N.
Homozygous alpha-synuclein p.A53V in familial Parkinson’s disease.
Neurobiol Aging. 2017 Sep 57;248:e7-248 e12.
2Uchihara Y, Kataoka H, Yoshino H, Syobatake R, Hattori N, Ueno S.
Parkin mutation may be associated with serious akinesia in a patient with Parkinson's disease.
J Neurol Sci. 2017;379 :119–121.
3Yamaguchi J, Suzuki C, Nanao T, Kakuta S, Ozawa K, Tanida I, Saitoh T, Sunabori T, Komatsu M, Tanaka K, Aoki S, Sakimura K, Uchiyama Y.
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis.
Autophagy. 2017 May 17:1-14. doi: 10.1080/15548627.2017.1314897.
4Osada T., Suzuki R., Ogawa A., Tanaka M., Hori M., Aoki S., Tamura Y., Watada H., Kawamori R., and Konishi S.
Functional subdivisions of the hypothalamus using areal parcellation and their signal changes related to glucose metabolism.
Neuroimage, 162, 1-12, 2017.
5Yamada T, Kerever A, Yoshimura Y, Suzuki Y, Nonaka R, Higashi K, Toida T, Mercier F, Arikawa-Hirasawa E
Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor-2 signaling impairment in the aged neurogenic niche.
J Neurochem. 2017 Aug;142(4):534-544. doi: 10.1111/jnc.14081. Epub 2017 Jun 20.
6Chihiro Akiba, Madoka Nakajima, Masakazu Miyajima, Ikuko Ogino, Eri Nakamura, Fumio Kanai, Norihiro Tada, Miyuki Kunichika, Mitsutaka Yoshida, Kinya Nishimura, Ritsuko Inoue, Masami Miura, Akihide Kondo, Hidenori Sugano, Hajime Arai:
Hippocampal accumulation of leucine-rich a2-glycoprotein contributes to age-related memory impairment.
Neurobiology of Aging, 60, 11-19, 2017
7Kimoto A, Ohnuma T, Toda A, Takebayashi Y, Higashiyama R, Tagata Y, Ito M, Ota T, Shibata N, Arai H.
Medium-chain triglycerides given in the early stage of mild-to-moderate Alzheimer's disease enhance memory function.
Psychogeriatrics.17(6),520-521,2017
8Wada H, Dohi T, Miyauchi K, Doi S, Naito R, Konishi H, Tsuboi S, Ogita M, Kasai T, Hassan A, Okazaki S, Isoda K, Suwa S, Daida H.
Prognostic impact of the geriatric nutritional risk index on long-term outcomes in patients who underwent percutaneous coronary intervention.
Am J Cardiol. 2017 Jun 1;119(11):1740-1745
9Akiba C, Nakajima M, Miyajima M, Ogino I, Miura M, Inoue R, Nakamura E, Kanai F, Tada N, Kunichika M, Yoshida M, Nishimura K, Kondo A, Sugano H, Arai H.
Leucine-rich α2-glycoprotein overexpression in the brain contributes to memory impairment.
Neurobiol Aging. 2017 Dec;60:11-19. doi: 10.1016/j.neurobiolaging.2017.08.014. Epub 2017 Aug 24.PMID: 28917663
10Suzuki Y, Sato T, Sugimoto M, Baskoro H, Karasutani K, Mitsui A, Nurwidya F, Arano N, Kodama Y, Hirano SI, Ishigami A, Seyama K, Takahashi K.
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
Biochem Biophys Res Commun. 2017 Oct 7;492(1):74-81.

主な研究業績(2016年)

1Kanae Yamamoto-Nonaka, Masato Koike, Katsuhiko Asanuma, Miyuki Takagi, JuaAlejandroOliva Trejo, Takuto Seki, Teruo Hidaka, Koichiro Ichimura, Tatsuo Sakai, Norihiro Tada, Takashi Ueno, Yasuo Uchiyama, Yasuhiko Tomino:
Cathepsin D in Podocytes is Important in the Pathogenesis of Proteinuria and CKD.
J. of the American Society of Nephrology, 2016 Sep;27(9):2685-700.
2Asao T, Fujiwara Y, Sunami K, Kitahara S, Goto Y, Kanda S, Horinouchi H, Nokihara H, Yamamoto N, Ichikawa H, Kohno T, Tsuta K, Watanabe S, Takahashi K, Ohe Y.
Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.
Lung Cancer. 2016 Mar; 93:77-81.
3Ando K, Fujino N, Mitani K, Ota C, Okada Y, Kondo T, Mizobuchi T, Kurihara M, Suzuki K, Hoshika Y, Ebana H, Kobayashi E, Takahashi K, Kubo H, Seyama K.
Isolation of Individual Cellular Components from Lung Tissues of Patients with Lymphangioleiomyomatosis.
Am J Physiol Lung Cell Mol Physiol. 2016 May 15; 310(10):L899-908.
4Jiang L, Konishi H, Nurwidya F, Takahashi F, Ebinuma H, Fujimura K, Takasu K, Jiang M, Bujo H, Daida H.
Deletion of LR11 Attenuates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cell Proliferation With Medial Thickening in Mice.
Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1972-9.
5Shigematsu M, Koga T, Ishimori A, Saeki K, Ishii Y, Taketomi Y, Ohba M, Jo-Watanabe A, Okuno T, Harada N, Harayama T, Shindou H, Li JD, Murakami M, Hoka S, Yokomizo T.
Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury.
Sci Rep. 2016 Oct 5;6:34560.
6Shukuya T, Mori K, Amann JM, Bertino EM, Otterson GA, Shields PG, Morita S, Carbone DP.
Relationship between Overall Survival and Response or Progression-Free Survival in Advanced Non-Small Cell Lung Cancer Patients Treated with Anti-PD-1/PD-L1 Antibodies.
J Thorac Oncol. 2016 Nov;11(11):1927-1939.
7Conedera S, Apaydin H, Li Y, Yoshino H, Ikeda A, Matsushima T, Funayama M, Nishioka K, Hattori N.
FBXO7 Mutations in Parkinson's Disease and Multiple System Atrophy.
Neurobiol Aging. 2016 Apr;40:192.e1-5.
8Sato S, Koike M, Funayama F, Ezaki J, Fukuda T, Uenn T, Uchiyama U, Hattori N.
Lysosomal storage of subunit c of mitochondrial ATP synthase in brain-specific Atp13a2-deficient mice.
Am J Pathol. 2016 Dec;186(12):3074-3082.
9Hadano S, Mitsui S, Pan L, Otomo A, Kubo M, Sato K, Ono S, Onodera W, Abe K, Chen X, Koike M, Uchiyama Y, Aoki M, Warabi E, Yamamoto M, Ishii T, Yanagawa T, Shang H, Yoshii F.
Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: Cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hum Mol Genet. 2016 Aug 1;25(15):3321-3340.
10Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, Li H, Li Q, Wang X, Uchiyama Y, Truttmann AC, Kroemer G, Puyal J, Blomgren K, Zhu C.
Neuroprotection by selective neuronal deletion of autophagy-related gene 7 in neonatal brain injury.
Autophagy. 2016;12(2):410-23.

英文原著(2015年)

1Ito Y, Kawano H, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Arai H, Kobayashi T, Hino O.
Establishment of Tsc2-deficient rat embryonic stem cells.
Int J Oncol. 2015 May; 46(5): 1944-1952.
2Liu C, Kanamaru Y, Watanabe T, Tada N, Horikoshi S, Suzuki Y, Liu Z, Tomino Y.
Targeted IgA Fc receptor I (FcαRI) therapy in the early intervention and treatment of pristane induced lupus nephritis in mice.
Clin Exp Immunol. 2015 Sep; 181(3): 407-416.
3Yoshihara T, Shimada K, Fukao K, Sai E, Sato-Okabayashi Y, Matsumori R, Shiozawa T, Alshahi H, Miyazaki T, Tada N, Daida H.
Omega 3 polyunsaturated fatty acids suppress the development of aortic aneurysms through the inhibition of macrophage-mediated inflammation.
Circ J. 2015; 79(7): 1470-1478.
4Schulz M,Kimura T,Akiyama O,Shimoji K, Spors B, Miyajima M, Thomale UW.
Endoscopic and microsurgical treatment of Sylvian fissure arachnoid cysts – clinical and radiological outcome.
World Neurosurg. 2015 Aug;84(2):327-36.
5Moriya M, Miyajima M, Nakajima M, Ogino I, Arai H.
Impact of cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus on the amyloid cascade.
PLoS One. 2015 Mar 30;10(3):e0119973.
6Kazui H, Miyajima M, Mori E, Ishikawa M;SINPHONI-2 Investigators.
Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomized trial.
Lancet Neurol.2015 Jun;14(6):585-94.
7Nakajima M, Miyajima M, Ogino I, Akiba C, Sugano H, Hara T, Fusegi K, Karagiozov K, Arai H:
Cerebrospinal fluid biomarkers for prognosis of long-term cognitive treatment outcomes in patients with idiopathic normal pressure hydrocephalus.
J Neurol Sci. 2015 Oct 15;357(1-2):88-95.
8Tsutsumi S, Ogino I, Miyajima M, Ito M, Arai H, Yasumoto Y:
Cerebrospinal fluid drainage through the diploic and spinal epidural veins.
J Anat 227: 297-301, 2015
9Kageyama H, Miyajima M, Ogino I, Nakajima M, Shimoji K, Fukai R, Miyake N, Nishiyama K, Mastumoto N, Arai H:
Panventriculomegaly with a wide foramen of Magendi and a large cisterna magna.
J Neurosurg2015 Dec4: 1-9
10Miyajima M, Arai H:
Evaluation of the production and absorption of cerebrospinal fluid.
Neurol Med Chir (Tokyo) 55(8): 647-656, 2015
11Komuro Y, Shimizu A, Shimoji K, Miyajima M, Arai H:
Posterior cranial vault distraction osteogenesis with barrel stave osteotomy in the treatment of craniosynostosis.
Neurol Med Chir (Tokyo) 55(8): 617-623, 2015
12Kawai E, Shibata N, Nagata T, Shinagawa S, Tagai K, Ohnuma T, Shimazaki H, Toda A,
Between KIBRA Polymorphism and Alzheimer's Disease with in a JapanesePopulation. 
Neuromolecular Med.2015:Jun;17(2):170-7. 
13Nagata T, Kobayashi N, Ishii J, Shinagawa S, Nakayama R, Shibata N, Kuerban B, Ohnuma T, Kondo K, Arai H, Yamada H, Nakayama K. 
Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease.
Dement Geriatr Cogn Dis Extra.2015:Mar 4;5(1):64-73.
14Ito Y, Kawano H, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Arai H, Kobayashi T, Hino O.
Establishment of Tsc2-deficient rat embryonic stem cells.
Int J Oncol. 2015 May; 46(5): 1944-1952.
15Liu C, Kanamaru Y, Watanabe T, Tada N, Horikoshi S, Suzuki Y, Liu Z, Tomino Y.
Targeted IgA Fc receptor I (FcαRI) therapy in the early intervention and treatment of pristane induced lupus nephritis in mice.
Clin Exp Immunol. 2015 Sep; 181(3): 407-416.
16Yoshihara T, Shimada K, Fukao K, Sai E, Sato-Okabayashi Y, Matsumori R, Shiozawa T, Alshahi H, Miyazaki T, Tada N, Daida H.
Omega 3 polyunsaturated fatty acids suppress the development of aortic aneurysms through the inhibition of macrophage-mediated inflammation.
Circ J. 2015; 79(7): 1470-1478.
17Watanabe T, Hanajima R, Shirota Y, Tsutsumi R, Shimizu T, Hayashi T, Terao Y, Ugawa Y, Katsura M, Kunimatsu A, Ohtomo K, Hirose S, Miyashita Y, Konishi S.
Effects of rTMS over presupplementary motor area on fronto-basal-ganglia network activity during stop-signal task.
Journal of Neuroscience, 35, 4813-4823, 2015
18Ueno S, Miyamoto N, Shimura H, Ueno Y, Watanabe M, Hayashi A, Hattori N, Urabe T.
Successful immune moderation treatment for progressive encephalomyelitis with rigidity and myoclonus.
Intern Med. 2015;54(2):219-21.
19Matsuo H, Tomiyama H, Satake W, Chiba T, Onoue H, Kawamura Y, Nakayama A, Shimizu S, Sakiyama M, Funayama M, Nishioka K, Shimizu T, Kaida K, Kamakura K, Toda T, Hattori N, Shinomiya N.
ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout. Ann Clin Transl Neurol.
2015 Mar;2(3):302-6.
20Fusegi K, Yoritaka A, Hattori N, Mori H.
Automatic behavior in Parkinson's disease.
Parkinsonism Relat Disord. 2015 Jan;21(1):84-5.
21Nishioka K, Oyama G, Yoshino H, Li Y, Matsushima T, Takeuchi C, Mochizuki Y, Mori-Yoshimura M, Murata M, Yamasita C, Nakamura N, Konishi Y, Ohi K, Ichikawa K, Terada T, Obi T, Funayama M, Saiki S, Hattori N.
High frequency of beta-propeller protein-associated neurodegeneration (BPAN) among patients with intellectual disability and young-onset parkinsonism.
Neurobiol Aging. 2015 May;36(5):2004.e9-2004.e15.
22Kino Y, Washizu C, Kurosawa M, Oma Y, Hattori N, Ishiura S, Nukina N.
Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins.
Hum Mol Genet. 2015 Feb 1;24(3):740-56.
23Kurosawa M, Matsumoto G, Kino Y, Okuno M, Kurosawa-Yamada M, Washizu C, Taniguchi H, Nakaso K, Yanagawa T, Warabi E, Shimogori T, Sakurai T, Hattori N, Nukina N.
Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice.
Hum Mol Genet. 2015 Feb 15;24(4):1092-105.
24Yamashiro K, Funabe S, Tanaka R, Fukumura Y, Takanashi M, Yao T, Hattori N.
Primary aortic sarcoma: a rare but critical cause of stroke.
Neurology. 2015 Feb 17;84(7):755-6.
25Asano T, Koike M, Sakata S, Takeda Y, Nakagawa T, Hatano T, Ohashi S, Funayama M, Yoshimi K, Asanuma M, Toyokuni S, Mochizuki H, Uchiyama Y, Hattori N, Iwai K.
Possible involvement of iron-induced oxidative insults in neurodegeneration.
Neurosci Lett. 2015 Feb 19;588:29-35.
26Tanaka Y, Ueno Y, Shimada Y, Yamashiro K, Tanaka R, Urabe T, Hattori N.
Paradoxical brain embolism associated with Kimura disease mimics watershed infarction.
J Stroke Cerebrovasc Dis. 2015 Feb;24(2):e55-7.
27Ueno Y, Koike M, Shimada Y, Shimura H, Hira K, Tanaka R, Uchiyama Y, Hattori N, Urabe T.
L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain.
J Cereb Blood Flow Metab. 2015 Mar;35(3):382-91.
28Shimo Y, Nishina K, Hatano T, Hattori N.
Sensory tricks for isolated speech-induced lingual dystonia.
BMJ Case Rep. 2015 Mar 5;2015.
29Nishikawa N, Shimo Y, Wada M, Hattori N, Kitazawa S.
Effects of aging and idiopathic Parkinson's disease on tactile temporal order judgment.
PLoS One. 2015 Mar 11;10(3):e0118331.
30Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study.
Lancet Neurol. 2015 Mar;14(3):274-82.
31Yatomi Y, Tanaka R, Shimada Y, Yamashiro K, Liu M, Mitome-Mishima Y, Miyamoto N, Ueno Y, Urabe T, Hattori N.
Type 2 diabetes reduces the proliferation and survival of oligodendrocyte progenitor cells in ishchemic white matter lesions.
Neuroscience. 2015 Mar 19;289:214-23.
32Hatano T, Saiki S, Okuzumi A, Mohney RP, Hattori N.
Identification of novel biomarkers for Parkinson's disease by metabolomic technologies.
J Neurol Neurosurg Psychiatry. 2015 Mar 20. pii: jnnp-2014-309676.
33Kawajiri S, Noda K, Ikeda A, Koinuma T, Tomizawa Y, Hattori N, Okuma Y.
Low dose of clonazepam is effective in the treatment of painless legs and moving toes syndrome: a case report.
Case Rep Neurol. 2015 Mar 21;7(1):59-62. doi: 10.1159/000380942. eCollection 2015 Jan-Apr. PubMed PMID: 25873890; PubMed Central PMCID: PMC4395820.
34Kobayashi M, Tanaka R, Yamashiro K, Ueno Y, Kato E, Miura S, Daida H, Hattori N.
Pre-existing Mobile Cardiac Thrombus and the Risk of Early Recurrent Embolism after Intravenous Thrombolysis: A Case Report.
J Stroke Cerebrovasc Dis. 2015 Jun;24(6):e161-3.
35Kino Y, Washizu C, Kurosawa M, Yamada M, Miyazaki H, Akagi T, Hashikawa T, Doi H, Takumi T, Hicks GG, Hattori N, Shimogori T, Nukina N.
FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis.
Acta Neuropathol Commun. 2015 Apr 25;3:24.
36Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S.
Variants associated with Gaucher disease in multiple system atrophy.
Ann Clin Transl Neurol. 2015 Apr;2(4):417-26.
37Ueno Y, Yamashiro K, Tanaka Y, Watanabe M, Miyamoto N, Shimada Y, Kuroki T, Tanaka R, Miyauchi K, Daida H, Hattori N, Urabe T.
Rosuvastatin may stabilize atherosclerotic aortic plaque: transesophageal echocardiographic study in the EPISTEME trial.
Atherosclerosis. 2015 Apr;239(2):476-82.
38Noda K, Hattori N, Okuma Y.
Hemiballism with leg predominance caused by contralateral subthalamic haemorrhage.
BMJ Case Rep. 2015 Apr 9;2015.
39Vaikath NN, Majbour NK, Paleologou KE, Ardah MT, van Dam E, van de Berg WD, Forrest SL, Parkkinen L, Gai WP, Hattori N, Takanashi M, Lee SJ, Mann DM, Imai Y, Halliday GM, Li JY, El-Agnaf OM.
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
Neurobiol Dis.2015 Jul;79:81-99.
40Nishioka K, Oyama G,Yoshino H, Li Y,Matsushima T,Takeuchi C,Mochizuki Y,Mori-Yoshimura M, Murata M, Yamasita C, Nakamura N,Konishi Y,Ohi K,Ichikawa K, Terada T,Obi T,Funayama M,Saiki S,Hattori N.
High frequency of beta-propeller protein-associated neurodegeneration (BPAN) among patients with intellectual disability and young-onset parkinsonism.
Neurobiol Aging. 2015 May;36(5):2004.e9-2004.e15.
41Matsumoto G, Shimogori T, Hattori N, Nukina N.
TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation.
Hum Mol Genet. 2015 Aug 1;24(15):4429-42.
42Shimo Y, Nakajima A, Hattori N.
Dopamine agonist withdrawal syndrome in a patient with restless legs syndrome without impulse control disorder or drug abuse.
Neurol Sci. 2015 Jun;36(6):1021-3.
43Fuse A, Furuya N, Kakuta S, Inose A, Sato M, Koike M, Saiki S, Hattori N.
VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process.
FEBS Lett. 2015 Jun 4;589(13):1430-6.
44Matsushima T, Nishioka K, Tanaka R, Yokoyama K, Hattori N.
Anterior opercular syndrome induced by Epstein-Barr virus encephalitis.
Neurocase. 2015 Jun 1:1-6.[Epub ahead of print] PubMed PMID: 26027635.
45Funayama M, Hattori N.
CHCHD2 and Parkinson's disease--authors' reply.
Lancet Neurol. 2015 Jul;14(7):682-3.
46Fukae J, Higuchi MA, Yanamoto S, Fukuhara K, Tsugawa J, Ouma S, Hatano T, Yoritaka A, Okuma Y, Kashihara K, Hattori N, Tsuboi Y.
Utility of the Japanese version of the 9-item Wearing-off Questionnaire.
Clin Neurol Neurosurg. 2015 Jul;134:110-5.
47Takahashi M, Ikeda J, Tomida T, Hirata K, Hattori N, Inoue Y.
Daytime symptoms of restless legs syndrome--clinical characteristics and rotigotine effectiveness.
Sleep Med. 2015 Jul;16(7):871-6.
48Fujimaki M, Kawajiri S, Ichikawa K, Tomizawa Y, Nakazato T, Noda K, Hattori N, Koike M,Okuma Y.
Lymphomatoid Granulomatosis with Central Nervous System Involvement Successfully Treated with Cyclophosphamide, High-dose Cytarabine, Irradiation: A Case Study.
CNS Neurosci Ther. 2015 Jul;21(7):610-2.
49Tanaka R, Yamashiro K, Okuma Y, Shimura H, Nakamura S, Ueno Y, Tanaka Y, Miyamoto N, Tomizawa Y, Nakahara T, Furukawa Y, Watada H, Kawamori R, Hattori N, Urabe T.
Effects of Pioglitazone for Secondary Stroke Prevention in Patients with Impaired Glucose Tolerance and Newly Diagnosed Diabetes: The J-SPIRIT Study.
J Atheroscler Thromb.2015;22(12):1305-16.
50Noda K, Nakajima S, Sasaki F, Ito Y, Kawajiri S, Tomizawa Y, Hattori N,Yamamoto T,Okuma Y.
Middle Cerebral Artery Occlusion Presenting as Upper Limb Monochorea.
J Stroke Cerebrovasc. 2015 Oct;24(10):e291-3.
51Yoritaka A, Kawajiri S, Yamamoto Y, Nakahara T, Ando M, Hashimoto K, Nagase M, Saito Y, Hattori N.
Randomized,double-blind,placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease.
Parkinsonism Relat Disord. 2015 Aug;21(8):911-6.
52Ueno S, Sekimoto-Tsuboi S, Ishiguro Y, Koinuma T, Eguchi H, Machida Y, Hattori N, Miwa H.
Good's syndrome with opportunistic infection of the central nervous system: a case report.
BMC Neurol. 2015 Aug 25;15:150.
53Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R.
The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.
PLoS Genet.2015 Sep 10;11(9):e1005503.
54Noda K, Tosaka Y, Ishiguro Y, Kawajiri S, Tomizawa Y, Hattori N, Okuma Y.
Delayed chorea after recovery from severe akinetic-rigid parkinsonism caused by extrapontine myelinolysis.
J Neurol Sci. 2015 Nov 15;358(1-2):498-500.
55Matsumoto SE, Motoi Y, Ishiguro K, Tabira T, Kametani F, Hasegawa M, Hattori N.
The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties.
Hum Mol Genet. 2015 Nov 15;24(22):6403-16.
56Bhidayasiri R, Hattori N, Jeon B, Chen RS, Lee MK, Bajwa JA, Mok VC, Zhang B, Syamsudin T, Tan LC, Jamora RD, Pisarnpong A, Poewe W.
Asian perspectives on the recognition and management of levodopa 'wearing-off' in Parkinson's disease.
Expert Rev Neurother. 2015;15(11):1285-97.
57Noda K, Kawajiri S, Tomizawa Y, Hattori N, Okuma Y.
Pisa syndrome in progressive supranuclear palsy: A case report.
Parkinsonism Relat Disord. 2015 Sep;21(9):1115-6.
58Yamashiro K, Tanaka R, Hoshino Y, Hatano T, Nishioka K, Hattori N.
The prevalence and risk factors of cerebral microbleeds in patients with Parkinson's disease.
Parkinsonism Relat Disord. 2015 Sep;21(9):1076-81.
59Hojo M, Ohta K, Iikura M, Hirashima J, Sugiyama H, Takahashi K.
The impact of co-existing seasonal allergic rhinitis caused by Japanese Cedar Pollinosis (SAR-JCP) upon asthma control status.
Allergol Int. 2015 Apr; 64(2): 150-5.
60Iida T, Shiba M, Yohino I, Miyaoka E, Asamura H, Date H, Okumura M, Tada H, Nakanishi Y, Dosaka H, Kobayashi H, Takahashi K, Inoue M, Yokoi K.
Surgical intervention for non–small-cell lung cancer patients with pleural carcinomatosis results from the Japanese lung cancer registry in 2004.
Journal of Thoracic Oncology. 2015 Jul; 10(7): 1076-1082.
61Ichikawa M, Kodama Y, Yoshimi K, Shiota S, Kotajima M, Nakajyo M, Seyama K, Fukuchi Y, Takahashi K.
Effects of transdermal tulobuterol on dyspnea and respiratory function during exercise in patients with chronic obstructive pulmonary disease.
J Thorac Dis. 2015 Apr; 7(4): 687-96.
62Itoigawa Y, Harada N, Harada S, Katsura Y, Makino F, Ito J, Nurwidya F, Kato M, Takahashi F, Atsuta R, Takahashi K.
TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells.
Respir Res. 2015 Apr; 16(1): 48.
63Iwakami S, Fujii M, Tsutsumi T, Sekimoto Y, Jo H, Hara M, Iwakami N, Takahashi K.
Autoimmune pulmonary alveolar proteinosis with primary lung cancer in a patient of very advanced years.
Geriatr Gerontol Int. 2015 May; 15(5): 666-7.
64Ko R, Kenmotsu H, Hisamatsu Y, Akamatsu H, Omori S, Nakashima K, Oyakawa T, Wakuda K, Shukuya T, Ono A, Imai H, Taira T, Naito T, Murakami H, Mori K, Endo M, Ohde Y, Takahashi K, Takahashi T.
The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.
Int J Clin Oncol. 2015 Aug; 20(4): 668-73.
65Sekiya M, Yoshimi K, Muraki K, Iwakami S, Togo S, Tamaki S, Dambara T, Takahashi K.
Do respiratory comorbidities limit the diagnostic usefulness of ultrasound-guided needle aspiration for subpleural lesions?
Respir Investig. 2015 May; 53(3): 98-103.
66Shiota S, Ichikawa M, Suzuki K, Fukuchi Y, Takahashi K.
Practical surrogate marker of pulmonary dysanapsis by simple spirometry: an observational case-control study in primary care.
BMC Fam Prct. 2015 Mar; 16(1): 41.
67Shukuya T, Ko R, Mori K, Kato M, Yagishita S, Kanemaru R, Honma Y, Shibayama R, Koyama R, Shimada N, Takahashi K.
Prognostic factors in non-small cell lung cancer patients who are recommended to receive single-agent chemotherapy (docetaxel or pemetrexed) as a second- or third-line chemotherapy: in the era of oncogenic drivers and molecular-targeted agents.
Cancer Chemother Pharmacol. 2015 Oct;76(4):771-6.
68Sugano K, Okuyama T, Iida S, Komatsu H, Ishida T, Kusumoto S, Uchida M, Nakaguchi T, Kubota Y, Ito Y, Takahashi K, Akechi T.
Medical Decision-Making Incapacity among Newly Diagnosed Older Patients with Hematological Malignancy Receiving First Line Chemotherapy: A Cross-Sectional Study of Patients and Physicians.
PLoS One. 2015 Aug; 10(8): e0136163.
69Tobino K, Johkoh T, Fujimoto K, Sakai F, Arakawa H, Kurihara M, Kumasaka T, Koike K, Takahashi K, Seyama K.
Computed tomographic features of lymphangioleiomyomatosis: Evaluation in 138 patients.
Eur J Radiol. 2015 Mar; 84(3): 534-41.
70Tajima K, Yae T, Javaid S, Tam O, Comaills V, Morris R, Wittner BS, Liu M, Engstrom A, Takahashi F, Black JC,
Ramaswamy S, Shioda T, Hammell M, Haber DA, Whetstine JR, Maheswaran S.
SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes.
Nature Commun. 2015; 6: 8257
71Yagishita S, Fujita Y, Kitazono S, Ko R, Nakadate Y, Sawada T, Kitamura Y, Shimoyama T, Maeda Y, Takahashi F, Takahashi K,Tamura T,Koizumi F.
Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer.
Mol Cancer Ther. 2015 Jun; 14(6): 1414-23.
72Nonaka R,Iesaki T,de Vega S,Daida H, Okada T, Sasaki T, and Arikawa-Hirasawa E.
Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase.
Physiol Rep. 2015 Jan 27;3(1).
73Iwata S, Ito M, Nakata T, Noguchi Y, Okuno T, Ohkawara B, Masuda A, Goto T, Adachi M, Osaka H, Nonaka R, Arikawa-Hirasawa E, Ohno K.
A missense mutation in domain III in HSPG2 in Schwartz–Jampel syndrome compromises secretion of perlecan into the extracellular space 
Neuromuscul Disord 2015 Aug;25(8):667-71..
74Kerever A, Yamada T, Suzuki Y Mercier F, Arikawa-Hirasawa, E.
Fractone aging in the subventricular zone of the lateral ventricle Journal of Chemical Neuroanatomy.
2015 Jul-Sep;66-67:52-60.
75Rinchai D, Riyapa D, Buddhisa S, Utispan K, Titball RW, Stevens MP, Stevens JM, Ogawa M, Tanida I, Koike M, Uchiyama Y, Ato M, Lertmemongkolchai G.
Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils.
Autophagy.2015 11:748-755.
76Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study.
Lancet Neurol,2015 14:274-282.
77Furuta A, Kikuchi H, Fujita H, Yamada D, Fujiwara Y, Kabuta T, Nishino I, Wada K, Uchiyama Y.
Property of Lysosomal Storage Disease associated with Midbrain Pathology in the CNS of LAMP-2-deficient Mice.
Am J Pathol.2015 185: 1713-1723.
78Nori S, Okada Y, Nishimura S, Ssaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano H.
Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition.
Stem Cell Rep.2015 4:1-14.
79Uemura N, Koike M, Ansai K, Kinoshita M, Fujiwara-Ishikawa T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R.
Axonal accumulation of alpha-synuclein in Gaucher disease model of medaka (Oryzias latipes) does not contribute to neurodegeneration.
Pros Genetics doi: 10.1371
80Nanao T, Koike M, Yamaguchi J, Sasaki M, Uchiyama Y.
Cellular localization and tissue distribution of endogenous DFCP1 protein.
Biomed Res,2015, 36:121-133.
81Kawano H, Ito Y, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Kobayashi T, Hino:
Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway.
Oncol Rep. 2015,34(5), 2251-2258.
82Takuma Yoshihara, Kazunori Shimada, Kosuke Fukao, Eiryu Sai, Yayoi Sato-Okabayashi, Rie Matsumori, Tomoyuki Shiozawa, Hamad Alshahi, Tetsuro Miyazaki, Norihiro Tada, Hiroyuki Daida:
Omega 3 Polyunsaturated Fatty Acids Suppress the Development of Aortic Aneurysms Through the Inhibition of Macrophage-Mediated Inflammation.
Circ J. 2015,79(7), 1470-1478.
83Hirano A, Ohara T, Takahashi A, Aoki M, Fuyuno Y, Ashikawa K, Morihara T, Takeda M, Kamino K, Oshima E, Okahisa Y, Shibata N, Arai H, Akatsu H, Ikeda M, Iwata N, Ninomiya T, Monji A, Kitazono T, Kiyohara Y, Kubo M, Kanba S. 
A genome-wide association study of late-onset Alzheimer's disease in a Japanese population. 
Psychiatr Genet. 2015 Aug;25(4):139-46.
84Tajima K, Yae T, Javaid S, Tam O, Comaills V, Morris R, Wittner BS, Liu M, Engstrom A, Takahashi F, Black JC, Ramaswamy S, Shioda T, Hammell M, Haber DA, Whetstine JR, Maheswaran S.
SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes.
Nature Commun. 2015; 6: 8257
85Yagishita S, Fujita Y, Kitazono S, Ko R, Nakadate Y, Sawada T, Kitamura Y, Shimoyama T, Maeda Y, Takahashi F, Takahashi K, Tamura T, Koizumi F.
Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer.
Mol Cancer Ther. 2015 Jun; 14(6): 1414-23.
86Shukuya T, Yamanaka T, Seto T, Daga H, Goto K, Saka H, Sugawara S, Takahashi T, Yokota S, Kaneda H, Kawaguchi T, Nagase S, Oguri T, Iwamoto Y, Nishimura T, Hattori Y, Nakagawa K, Nakanishi Y, Yamamoto N; West Japan Oncology Group.
Nedaplatin plus docetaxel versus cisplatin plus docetaxel for advanced or relapsed squamous cell carcinoma of the lung (WJOG5208L): a randomised, open-label, phase 3 trial.
Lancet Oncol. 2015 Dec;16(16):1630-8.
87Itoigawa Y, Harada N, Harada S, Katsura Y, Makino F, Ito J, Nurwidya F, Kato M, Takahashi F, Atsuta R, Takahashi K.
TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells.
Respir Res. 2015 Apr; 16(1): 48.
88Ando K, Kuraishi H, Nagaoka T, Tsutsumi T, Hoshika Y, Kimura T, Ienaga H, Morio Y, Takahashi K.
Potential Role of CT Metrics in Chronic Obstructive Pulmonary Disease with Pulmonary Hypertension.
Lung. 2015 [Epub ahead of print]
89Ebana H, Otsuji M, Mizobuchi T, Kurihara M, Takahashi K, Seyama K.
Pleural Covering Application for Recurrent Pneumothorax in a Patient with Birt-Hogg-Dubé Syndrome.
Ann Thorac Cardiovasc Surg. 2015. [Epub ahead of print]
90Katsura Y, Harada N, Harada S, Ishimori A, Makino F, Ito J, Kamachi F, Okumura K, Akiba H, Atsuta R, Takahashi K.
Characteristics of alveolar macrophages from murine models of OVA-induced allergic airway inflammation and LPS-induced acute airway inflammation.
Exp Lung Res. 2015;41(7):370-82.
91Takahashi K, Porcel JM, Lee P, Leung CC.Year in review 2014:
Lung cancer, pleural diseases, respiratory infections and tuberculosis, bronchoscopic intervention and imaging.
Respirology. 2015 May;20(4):674-83.
92Fujimoto Y, Togo S, Tulafu M, Shimizu K, Hayashi T, Uekusa T, Honma Y, Namba Y, Takamochi K, Oh S, Suzuki K, Takahashi K.
Variation in the expression levels of predictive chemotherapy biomarkers in histological subtypes of lung adenocarcinoma: an immunohistochemical study of tissue samples.
Int J Clin Exp Pathol. 2015 Sep 1;8(9):10523-33
93Miura S, Kaira K, Kaira R, Akamatsu H, Ono A, Shukuya T, Tsuya A, Nakamura Y, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Yamamoto N.
The efficacy of amrubicin on central nervous system metastases originating from small-cell lung cancer: a case series of eight patients.
Invest New Drugs. 2015 Jun;33(3):755-60.
94Akamatsu H, Ono A, Shukuya T, Tsuya A, Nakamura Y, Kenmotsu H, Naito T, Murakami H, Endo M, Nakajima T, Yamamoto N, Takahashi T.
Disease flare after gefitinib discontinuation.
Respir Investig. 2015 Mar;53(2):68-72.
95Hishida T, Tsuboi M, Shukuya T, Takamochi K, Sakurai H, Yoh K, Ohashi Y, Kunitoh H.
Multicenter observational cohort study of post-operative treatment for completely resected non-small-cell lung cancer of pathological Stage I (T1 >2 cm and T2 in TNM classification version 6).
Jpn J Clin Oncol. 2015 May;45(5):499-501.
96Imai H, Mori K, Wakuda K, Ono A, Akamatsu H, Shukuya T, Taira T, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Nakajima T, Yamamoto N, Takahashi T.
Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer.
Ann Thorac Med. 2015 Jan-Mar;10(1):61-6.
97Kenmotsu H, Naito T, Mori K, Ko R, Ono A, Wakuda K, Imai H, Taira T, Murakami H, Endo M, Takahashi T.
Effect of platinum-based chemotherapy for non-small cell lung cancer patients with interstitial lung disease.
Cancer Chemother Pharmacol. 2015 Mar;75(3):521-6.
98Mizugaki H, Yamamoto N, Nokihara H, Fujiwara Y, Horinouchi H, Kanda S, Kitazono S, Yagishita S, Xiong H, Qian J, Hashiba H, Shepherd SP, Giranda V, Tamura T.
A phase 1 study evaluating the pharmacokinetics and preliminary efficacy of veliparib (ABT-888) in combination with carboplatin/paclitaxel in Japanese subjects with non-small cell lung cancer (NSCLC).
Cancer Chemother Pharmacol. 2015 Nov;76(5):1063-72.
99Yagishita S, Horinouchi H, Sunami KS, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Sumi M, Shiraishi K, Kohno T, Furuta K, Tsuta K, Tamura T, Ohe Y.
Impact of KRAS mutation on response and outcome of patients with stage III non-squamous non-small cell lung cancer.
Cancer Sci. 2015 Oct;106(10):1402-7.
100Horinouchi H, Yamamoto N, Fujiwara Y, Sekine I, Nokihara H, Kubota K, Kanda S, Yagishita S, Wakui H, Kitazono S, Mizugaki H, Tokudome T, Tamura T.
Phase I study of ipilimumab in phased combination with paclitaxel and carboplatin in Japanese patients with non-small-cell lung cancer.
Invest New Drugs. 2015 Aug;33(4):881-9.
101Fujita Y, Yagishita S, Hagiwara K, Yoshioka Y, Kosaka N, Takeshita F, Fujiwara T, Tsuta K, Nokihara H, Tamura T, Asamura H, Kawaishi M, Kuwano K, Ochiya T.
The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer.
Mol Ther. 2015; 23(4):717-27.
102Fujita Y, Yagishita S, Takeshita F, Yamamoto Y, Kuwano K, Ochiya T.
Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer.
Oncotarget. 2015. 20;6(5):3335-45.
103Yagishita S, Horinouchi H, Katsui Taniyama T, Nakamichi S, Kitazono S, Mizugaki H, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Sumi M, Shiraishi K, Kohno T, Furuta K, Tsuta K, Tamura T.
Epidermal growth factor receptor mutation is associated with longer local control after definitive chemoradiotherapy in patients with stage III nonsquamous non-small-cell lung cancer.
Int J Radiat Oncol Biol Phys. 2015 Jan 1;91(1):140-8.
104Li YJ, Kanaji N, Wang XQ, Sato T, Nakanishi M, Kim M, Michalski J, Nelson AJ, Farid M, Basma H, Patil A, Toews ML, Liu X, Rennard SI.
Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition.
Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:1-9.
105Ikari J, Smith LM, Nelson AJ, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Feghali-Bostwick C, Liu X, DeMeo DL, Rennard SI.
Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro.
In Vitro Cell Dev Biol Anim. 2015 Apr;51(4):390-9.
106Wakida K, Watanabe Y, Kumasaka T, Seyama K, Mitani K, Hiraki T, Kamimura G, Nagata T, Nakamura Y, Sato M.
Lymphangioleiomyomatosis in a Male.
Ann Thorac Surg. 2015 Sep;100(3):1105-7.
107Adachi K, Miki Y, Saito R, Hata S, Yamauchi M, Mikami Y, Okada Y, Seyama K, Kondo T, Sasano H.
Intracrine steroid production and mammalian target of rapamycin pathways in pulmonary lymphangioleiomyomatosis.
Hum Pathol. 2015 Nov;46(11):1685-93.
108Gupta N, Meraj R, Tanase D, James LE, Seyama K, Lynch DA, Akira M, Meyer CA, Ruoss SJ, Burger CD, Young LR, Almoosa KF, Veeraraghavan S, Barker AF, Lee AS, Dilling DF, Inoue Y, Cudzilo CJ, Zafar MA, McCormack FX.
Accuracy of chest high-resolution computed tomography in diagnosing diffuse cystic lung diseases.
Eur Respir J. 2015 Oct;46(4):1196-9.
109Asao T, Nokihara H, Yoh K, Niho S, Goto K, Ohmatsu H, Kubota K, Yamamoto N, Sekine I, Kunitoh H, Fujiwara Y, Ohe Y.
Phase II study of amrubicin at a dose of 45 mg/m2 in patients with previously treated small-cell lung cancer.
Jpn J Clin Oncol. 2015 Oct;45(10):941-6.
110Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S.
ICOS promotes group 2 innate lymphoid cell activation in lungs.
Biochem Biophys Res Commun. 2015 Aug 7;463(4):739-45.
111Sai E, Shimada K, Yokoyama T, Sato S, Nishizaki Y, Miyazaki T, Hiki M, Tamura Y, Aoki S, Watada H, Kawamori R, Daida H.
Evaluation of myocardial triglyceride accumulation assessed by 1H-magnetic resonance spectroscopy in apparently healthy Japanese subjects.
Intern Med. 2015;54(4):367-73.
112Nishitani-Yokoyama M, Miyauchi K, Shimada K, Miyazaki T, Ogita M, Okazaki S, Shioya M, Koba S, Tsujita H, Kobayashi Y, Daida H.
Effects of phase II comprehensive cardiac rehabilitation on coronary plaque volume after acute coronary syndrome.
Int Heart J. 2015;56(6):597-604.
113Alshahi H, Shimada K, Miyauchi K, Yoshihara T, Sai E, Shiozawa T, Naito R, Aikawa T, Ouchi S, Kadoguchi T, Miyazaki T, Daida H.
Elevated Circulating Levels of Inflammatory Markers in Patients with Acute Coronary Syndrome.
Int J Vasc Med. 2015;2015:805375.
114Yoshihara T, Shimada K, Fukao K, Sai E, Sato-Okabayashi Y, Matsumori R, Shiozawa T, Alshahi H, Miyazaki T, Tada N, Daida H.
Omega 3 polyunsaturated fatty acids suppress the development of aortic aneurysms through the inhibition of macrophage-mediated inflammation.
Circ J. 2015;79(7):1470-8.
115Akita K, Isoda K, Shimada K, Daida H.
Dipeptidyl-peptidase-4 inhibitor, alogliptin, attenuates arterial inflammation and neointimal formation after injury in low-density lipoprotein (LDL) receptor-deficient mice.
J Am Heart Assoc, 2015; 4: e001469
116Naito R, Miyauchi K, Ogita M, Tsuboi S, Konishi H, Dohi T, Tamura H, Okazaki S, Isoda K, Daida H.
Clinical outcomes following percutaneous coronary intervention before and after introduction of drug-eluting stent.
Cardiovasc Interv Ther, 2015; 30: 338-46
117Konishi H, Miyauchi K, Tsuboi S, Ogita M, Naito R, Dohi T, Kasai T, Tamura H, Okazaki S, Isoda K, Daida H.
Impact of the HAS-BLED Score on Long-Term Outcomes After Percutaneous Coronary Intervention
Am J Cardiol, 2015; 116: 527-531
118Ogita M, Miyauchi K, Kasai T, Doi S, Wada H, Naito R, Konishi H, Tsuboi S, Dohi T, Tamura H, Okazaki S, Daida H.
Impact of preprocedual high-sensitive C-reactive protein levels on long-term clinical outcomes of patients with stable coronary artery disease and chronic kidney disease who were treated with drug-eluting stents.
J Cardiol. 2015; 66: 15-21.
119Ogita M, Miyauchi K, Tsuboi S, Shitara J, Endo H, Wada H, Doi S, Naito R, Konishi H, Dohi T, Kasai T, Tamura H, Okazaki S, Suwa S, Daida H.
Impact of combined C-reactive protein and high-density lipoprotein cholesterol levels on long-term outcomes in patients with coronary artery disease after a first percutaneous coronary intervention.
Am J Cardiol. 2015; 116: 999-1002.
120Naito R, Miyauchi K, Ogita M, Tsuboi S, Konishi H, Okai I, Tamura H, Kasai T, Okazaki S, Daida H.
Comparison of long-term clinical outcomes between sirolimus- and paclitaxel-eluting stents in real-world clinical practice.
Heart Vessels. 2015; 30: 746-751.
121Naito R, Miyauchi K, Konishi H, Tsuboi S, Ogita M, Dohi T, Kasai T, Tamura H, Okazaki S, Isoda K, Daida H.
Temporal trends in the Clinical Outcomes after Percutaneous Coronary Intervention from 1984 to 2010 -Report from the Juntendo PCI Registry-.
Circ J. 2015; 80: 93-100.
122Fujimoto S, Kondo T, Kumamaru KK, Shinozaki T, Takamura K, Kawaguchi Y, Matsumori R, Hiki M, Miyauchi K, Daida H, Rybicki FJ.
Prognostic Value of Coronary Computed Tomography (CT) Angiography and Coronary Artery Calcium Score Performed Before Revascularization.
J Am Heart Assoc. 2015 Aug 21;4(8).
123Ohmura H, Mita T, Taneda Y, Sugawara M, Funayama H, Matsuoka J, Watada H, Daida H, SPIRITS-J Study Investigators.
Efficacy and safety of sitagliptin in Japanese patients with type 2 diabetes.
J Clin Med Res, 2015; 7: 211-219
124Fujimoto S, Kondo T, Yamamoto H, Yokoyama N, Tarutani Y, Takamura K, Urabe Y, Konno K, Nishizaki Y, Shinozaki T, Kihara Y, Daida H, Isshiki T, Takase S.
Development of new risk score for pre-test probability od obstructive coronary artery disease based on coronary CT angiography.
Heart Vessels.2015;30: 563-571
125Naito R, Miyauchi K, Konishi H, Tsuboi S, Okazaki S, Daida H.
Early Definite Stent Thrombosis with Everolimus-eluting Stents.
Clinical Case Reports 2015; 3: 854
126Naito R, Miyauchi K, Konishi H, Tsuboi S, Ogita M, Dohi T, Kasai T, Tamura H, Okazaki S, Isoda K, Daida H.
Gender difference in long-term clinical outcomes following percutaneous coronary intervention during 1984 – 2008.
Atherosclerosis, 2015; 247: 105
127Shibayama K, Daimon M, Watanabe H, Kawata T, Miyazaki S, Morimoto-Ichikawa R, Maruyama M, Chiang SJ, Miyauchi K, Daida H.
Significance of Coronary Artery Disease and Left Ventricular Afterload in Unoperated Asymptomatic Aortic Stenosis.
Circ J. 2016 Jan 25;80(2):519-25
128Ueno Y, Yamashiro K, Tanaka Y, Watanabe M, Miyamoto N, Shimada Y, Kuroki T, Tanaka R, Miyauchi K, Daida H, Hattori N, Urabe T.
Rosuvastatin may stabilize atherosclerotic aortic plaque: transesophageal echocardiographic study in the EPISTEME trial.
Atherosclerosis, 2015; 239: 476-82
129Konishi H, Miyauchi K, Kasai T, Tsuboi S, Ogita M, Naito R, Sai E, Fukushima Y, Katoh Y, Okai I, Tamura H, Okazaki S, Daida H.
Impact of Lipoprotein(a) as Residual Risk on Long-Term Outcomes in Patients After Percutaneous Coronary Intervention.
Am J Cardiol, 2015; 115: 157-60
130Kurano M, Suzuki A, Inoue A, Tokuhara Y, Kano K, Matsumoto H, Igarashi K, Ohkawa R, Nakamura K, Dohi T, Miyauchi K, Daida H, Tsukamoto K, Ikeda H, Aoki J, Yatomi Y.
Possible Involvement of Minor Lysophospholipids in the Increase in Plasma Lysophosphatidic Acid in Acute Coronary Syndrome.
Arterioscler Thromb Vasc Biol, 2015; 32: 463-70
131Mizuno A, Miyauchi K, Nishizaki Y, Yamazoe M, Komatsu I, Asano T, Mitsuhashi H, Nishi Y, Niwa K, Daida H.
Impact of the augmentation time ratio on direct measurement of central aortic pressure in the presence of coronary artery disease.
Hypertens Res, 2015; 38: 684-9
132Dai Y, Takagi A, Konishi H, Miyazaki T, Masuda H, Shimada K, Miyauchi K, Daida H.
Long-term outcomes of rotational atherectomy in coronary bifurcation lesions.
Exp Ther Med. 10:2375-2383;2015.
133Tomita Y, Kasai T, Kisaka T, Rossiter HB, Kihara Y, Wasserman K, Daida H.
Altered breathing syndrome in heart failure: newer insights and treatment options.
Curr Heart Fail Rep. 2015; 12: 158-165.
134Shimada K, Miyauchi K, Daida H.
Azelnidipine and glucose tolerance: possible I ndications and treatment selection for hypertensive patients with metabolic disorders.
Expert Rev Cardiovasc Ther. 13:23-31;2015
135Miyajima M, Nakajima M, Ogino I, Kunichika M, Arai H:
An autopsy case of long-standing overt ventriculomegaly in adults (LOVA) –neuropathhological investigation-.
J Hydrocephalus 7: 6-10, 2015
136Hori M, Kamiya K, Nakanishi A, Fukunaga I, Miyajima M, Nakajima M, Suzuki M, Suzuki Y, Irie R, Kamagata K, Arai H, Aoki S:
Prospective estimation of mean axon diameter and extra-axonal space of the posterior limb of the internal capsule in patients with idiopathic normal pressure hydrocephalus before and after a lumboperitoneal shunt by using q-space diffusion MRI.
Eur Radiol 2015 Dec 22
137Yatomi Y, Tanaka R, Shimada Y, Yamashiro K, Liu M, Mitome-Mishima Y, Miyamoto N, Ueno Y, Urabe T, Hattori N.
Type 2 diabetes reduces the proliferation and survival of oligodendrocyte progenitor cells in ishchemic white matter lesions.
Neuroscience. 2015;289:214-23.
138Ning L, Xu Z, Furuya N, Nonaka R, Yamada Y, Arikawa-Hirasawa E.
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Matrix Biol. 2015 Aug 28.
139de Vega S, Hozumi K, Suzuki N, Nonaka R, Seo E, Takeda A, Ikeuchi T, Nomizu M, Yamada Y, Arikawa-Hirasawa E.
Identification of Peptides Derived from the C-terminal Domain of Fibulin-7 Active for Endothelial Cell Adhesion and Tube Formation Disruption.
Biopolymers. 2015 Oct 22.

英文原著(2014年)

1Okazaki H, Lin Q, Nishikawa K, Ohtsuji N, Tsurui H, Ohtsuji M, Amano H, Tada N, Sudo K, Nishimura H, Shirai T, Hirose S.
TNF α but not IL-17 is critical in the pathogenesis of rheumatoid arthritis spontaneously occurring in a unique-FcγRIIB-deficient mouse model.
Mod Rheumatol. 2014 Nov; 24(6): 931-938.
2Oliva Trejo JA, Asanuma K, Kim E-H, Takagi-Akiba M, Nonaka K, Hidaka T, Komatsu M, Tada N, Ueno T.
Transient increase in proteinuria, poly-ubiquitylated proteins and ER stress markers in podocyte-specific autophagy-deficient mice following unilateral nephrectomy.
Biochem Biophys Res Commun. 2014 Apr; 446(4): 1190-1196.
3Furuya N, Ikeda SI, Sato S, Soma S, Ezaki J, Trejo JA, Takeda-Ezaki M, Fujimura T, Arikawa-Hirasawa E, Tada N, Komatsu M, Tanaka K, Kominami E, Hattori N, Ueno T.
PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation.
Autophagy. 2014 Apr; 10(4): 631-641.
4Nakajima M, Sugano H, Iimura Y, Higo T, Nakanishi H, Shimoji K, Karagiozov K, Miyajima M, Arai H:
Sturge-Weber syndrome with spontaneous intracerebral hemorrhage in childhood.
J Neurosurg Pediatr. 2014 Jan;13(1):90-3.
5Kamiya K, Hori M, Miyajima M, Nakajima M, Suzuki Y, Kamagata K, Suzuki M, Arai H, Ohtomo K, Aoki S:
Axon diameter and intra-axonal volume fraction of the corticospinal tract in idiopathic normal pressure hydrocephalus measured by q-space imaging.
PLoS One. 2014 Aug 5;9(8):e103842.
6Tsutsumi S, Ogino I, Miyajima M, Nakamura M, Yasumoto Y, Arai H, Ito M:
Cranial Arachnoid Protrusions and Contiguous Diploic Veins in CSF Drainage.
AJNR Am J Neuroradiol. 2014 Sep;35(9):1735-9.
7Nakajima M, Miyajima M, Ogino I, Sugano H, Akiba C, Domon N, Karagiozov KL, Arai H:
Use of External Lumbar Cerebrospinal Fluid Drainage and Lumboperitoneal Shunts with Strata NSC Valves in Idiopathic Normal Pressure Hydrocephalus: A Single-Center Experience.
World Neurosurg. 2014 Aug 6. pii: S1878-8750(14)00707-4.
8Okumura A, Yamamoto T, Miyajima M, Shimojima K, Kondo S, Abe S, Ikeno M, Shimizu T:
3p Interstitial Deletion Including PRICKLE2 in Identical Twins With Autistic Features.
Pediatr Neurol 51(5): 730-733, 2014
9Nakashima M, Miyajima M, Sugano H, Iimura Y, Kato M, Tsurusaki Y, Miyake N, Saitsu H, Arai H, Matsumoto N:
The somatic GNAQ mutation c.548G>A (p.R183Q) is consistently found in Sturge-Weber syndrome.
Journal of Human Genetics 59(2):691-693, 2014
10Shimoji T, Tominaga D, Shimoji K, Miyajima M:
Analysis of pre and post-operative symptoms of patients with mild trigonocephaly using several developmental and psychology tests.
Childs Nerv Syst 2014 Dec 3[Epub ahead of print]
11Shibata N, Nagata T, Tagai K, Shinagawa S, Ohnuma T, Kawai E, Kasanuki K, Shimazaki H, Toda A, Tagata Y, Nakada T, Nakayama K, Yamada H, Arai H. 
Association between the catechol-O-methyltransferase polymorphism Val158Met and Alzheimer's disease in a Japanese population. 
Int J Geriatr Psychiatry.2014:Dec 9. doi:10.1002/gps.4237.
12Okazaki H, Lin Q, Nishikawa K, Ohtsuji N, Tsurui H, Ohtsuji M, Amano H, Tada N, Sudo K, Nishimura H, Shirai T, Hirose S.
TNF α but not IL-17 is critical in the pathogenesis of rheumatoid arthritis spontaneously occurring in a unique-FcγRIIB-deficient mouse model.
Mod Rheumatol. 2014 Nov; 24(6): 931-938.
13Oliva Trejo JA, Asanuma K, Kim E-H, Takagi-Akiba M, Nonaka K, Hidaka T, Komatsu M, Tada N, Ueno T.
Transient increase in proteinuria, poly-ubiquitylated proteins and ER stress markers in podocyte-specific autophagy-deficient mice following unilateral nephrectomy.
Biochem Biophys Res Commun. 2014 Apr; 446(4): 1190-1196.
14Furuya N, Ikeda SI, Sato S, Soma S, Ezaki J, Trejo JA, Takeda-Ezaki M, Fujimura T, Arikawa-Hirasawa E, Tada N, Komatsu M, Tanaka K, Kominami E, Hattori N, Ueno T.
PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation.
Autophagy. 2014 Apr; 10(4): 631-641.
15Katsura M, Hirose S, Sasaki H, Mori H, Kunimatsu A, Ohtomo K, Jimura K. Konishi S.
Decreased fronto-temporal interaction during fixation after memory retrieval.
PLoS ONE, 9, e110798, 2014
16Jimura K*, Hirose S*, Kunimatsu A, Ohtomo K, Koike Y, Konishi S.
Late development of brain-behavior correlations during response inhibition.
Neuroscience, 274, 383-392, 2014
17Watanabe T, Kan S, Koike T, Misaki M, Konishi S, Miyauchi S, Miyashita Y, Masuda N.
Network-dependent modulation of brain activity during sleep.
Neuroimage, 98, 1-10, 2014
18Hirose S, Jimura K, Kunimatsu A, Abe O, Ohtomo K, Miyashita Y, Konishi S.
Changes in cerebro-cerebellar interaction during response inhibition after performance improvement.
Neuroimage, 99, 142-148, 2014
19Watanabe T, Hanajima R, Shirota Y, Ohminami S, Tsutsumi R, Terao Y, Ugawa Y, Hirose S, Miyashita Y, Konishi S, Kunimatsu A, Ohtomo K.
Bidirectional effects on inter-hemispheric resting-state functional connectivity induced by excitatory and inhibitory repetitive transcranial magnetic stimulation.
Human Brain Mapping, 35, 1896-1905, 2014
20Watanabe T, Hirose S, Wada H, Imai Y, Machida T, Shirouzu I, Konishi S, Miyashita Y, Masuda N.
Energy landscapes of resting-state brain networks.
Frontiers in Neuroinformatics, 8, 12, 2014
21Kumano H, Uka T.
Visual impairment by surrounding noise is due to interactions among stimuli in the higher-order visual cortex.
J Neurophysiol 112: 620-630, 2014
22Hongo H, Tanaka Y, Shimada Y, Tanaka R, Hattori N, Urabe T.
Dermatomal sensory manifestations in lateral medullary infarction.
J Stroke Cerebrovasc Dis. 2014 Jan;23(1):182-3.
23Shen Q, Yamano K, Head BP, Kawajiri S, Cheung JT, Wang C, Cho JH, Hattori N, Youle RJ, van der Bliek AM.
Mutations in Fis1 disrupt orderly disposal of defective mitochondria.
Mol Biol Cell. 2014 Jan;25(1):145-59.
24Shimo Y, Natori S, Oyama G, Nakajima M, Ishii H, Arai H, Hattori N.
Subthalamic deep brain stimulation for a Parkinson's disease patient with duplication of SNCA.
Neuromodulation. 2014 Jan;17(1):102-3.
25Hattori N.
Cerebral organoids model human brain development and microcephaly.
Mov Disord. 2014 Feb;29(2):185.
26Mori A, Ueno Y, Kuroki T, Hoshino Y, Shimura H, Sekiguchi Y, Noguchi M, Hamada Y, Kusunoki S, Hattori N, Urabe T.
Motor-dominant polyneuropathy due to IgM monoclonal antibody against disialosyl gangliosides in a patient with mantle cell lymphoma.
J Neurol Sci. 2014 Feb 15;337(1-2):215-8.
27Oyama G, Umemura A, Shimo Y, Nishikawa N, Nakajima A, Jo T, Nakajima M, Ishii H, Yamada D, Takanashi M, Arai H, Nanba E, Hattori N.
Posterior Subthalamic Area Deep Brain Stimulation for Fragile X-Associated Tremor/Ataxia syndrome.
Neuromodulation. 2014 Dec;17(8):721-3.
28Tomizawa Y, Tanaka R, Sekiguchi K, Oji Y, Tanaka Y, Yamashiro K, Hattori N.
Cerebral infarction in a case of Parry-Romberg syndrome.
J Stroke Cerebrovasc Dis. 2014 Feb;23(2):393-4.
29Ueno Y, Yamashiro K, Tanaka Y, Watanabe M, Shimada Y, Kuroki T, Miyamoto N, Daimon M, Tanaka R, Miyauchi K, Daida H, Hattori N, Urabe T.
Rationale and design of the EPISTEME trial: efficacy of post-stroke intensive rosuvastatin treatment for aortogenic embolic stroke.
Cardiovasc Drugs Ther. 2014 Feb;28(1):79-85.
30Yamanaka T, Tosaki A, Kurosawa M, Matsumoto G, Koike M, Uchiyama Y, Maity SN, Shimogori T, Hattori N, Nukina N.
NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.
Nat Commun. 2014 Feb 25;5:3354.
31Fukae J, Ishikawa K, Hatano T, Yoritaka A, Takanashi M, Shimo Y, Tsugawa J, Tsuboi Y, Hattori N.
Serum uric acid concentration is linked to wearing-off fluctuation in Japanese Parkinson's disease patients.
J Parkinsons Dis. 2014;4(3):499-505.
32Hatano T, Hattori N, Kawanabe T, Terayama Y, Suzuki N, Iwasaki Y, Fujioka T; Yokukansan Parkinson’s Disease Study Group.
An exploratory study of the efficacy and safety of yokukansan for neuropsychiatric symptoms in patients with Parkinson's disease.
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33Kamagata K, Tomiyama H, Hatano T, Motoi Y, Abe O, Shimoji K, Kamiya K, Suzuki M, Hori M, Yoshida M, Hattori N, Aoki S.
A preliminary diffusional kurtosis imaging study of Parkinson disease: comparison with conventional diffusion tensor imaging.
Neuroradiology. 2014 Mar;56(3):251-8.
34Kerever A, Mercier F, Nonaka R, de Vega S, Oda Y, Zalc B, Okada Y, Hattori N, Yamada Y, Arikawa-Hirasawa E.
Perlecan is required for FGF-2 signaling in the neural stem cell niche.
Stem Cell Res. 2014 Mar;12(2):492-505.
35Funabe S, Tanaka R, Hayashi A, Yamashiro K, Shimura H, Hattori N.
Reversible dropped head syndrome after hemispheric striatal infarction.
J Stroke Cerebrovasc Dis. 2014 Apr;23(4):785-7.
36Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo JA, Takeda-Ezaki M, Fujimura T, Arikawa-Hirasawa E, Tada N, Komatsu M, Tanaka K, Kominami E, Hattori N, Ueno T.
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Autophagy. 2014 Apr;10(4):631-41.
37Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, Kawajiri S, Sasaki H, Koike M, Tsuboi Y, Hattori N.
P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway.
PLoS One. 2014 Apr 10;9(4):e94645.
38Li Y, Sekine T, Funayama M, Li L, Yoshino H, Nishioka K, Tomiyama H, Hattori N.
Clinicogenetic study of GBA mutations in patients with familial Parkinson's disease.
Neurobiol Aging. 2014 Apr;35(4):935.e3-8.
39Motoi Y, Shimada K, Ishiguro K, Hattori N.
Lithium and autophagy.
ACS Chem Neurosci. 2014 Jun 18;5(6):434-42.
40Noda K, Hattori N, Okuma Y.
Primary central nervous system lymphoma presenting as choreoathetosis.
BMJ Case Rep. 2014 Apr 16;2014. pii: bcr2013203353.
41Okuzumi A, Hatano T, Nakahara T, Yokoyama K, Hattori N.
Ophthalmic nerve hypertrophy in chronic inflammatory demyelinating polyradiculoneuropathy.
Neurology. 2014 Apr 29;82(17):1566-7.
42Yamanaka T, Wong HK, Tosaki A, Bauer PO, Wada K, Kurosawa M, Shimogori T, Hattori N, Nukina N.
Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation.
PLoS One. 2014 Apr 4;9(4):e93891.
43Yamashiro K, Tanaka R, Tanaka Y, Miyamoto N, Shimada Y, Ueno Y, Urabe T, Hattori N.
Visceral fat accumulation is associated with cerebral small vessel disease.
Eur J Neurol. 2014 Apr;21(4):667-73.
44Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, Imoto M.
Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease.
PLoS One. 2014 Jun 24;9(6):e100395.
45Ishikawa K, Motoi Y, Mizuno Y, Kubo S, Hattori N.
Effects of donepezil dose escalation in Parkinson's patients with dementia receiving long-term donepezil treatment: an exploratory study.
Psychogeriatrics. 2014 Jun;14(2):93-100.
46Nishioka K, Funayama M, Vilariño-Güell C, Ogaki K, Li Y, Sasaki R, Kokubo Y, Kuzuhara S, Kachergus JM, Cobb SA, Takahashi H, Mizuno Y, Farrer MJ, Ross OA, Hattori N.
EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population.
Parkinsonism Relat Disord. 2014 Jun;20(6):659-61.
47Shiba-Fukushima K, Inoshita T, Hattori N, Imai Y.
PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.
PLoS Genet. 2014 Jun 5;10(6):e1004391.
48Hori M, Yoshida M, Yokoyama K, Kamagata K, Kumagai F, Fukunaga I, Kamiya K, Suzuki M, Masutani Y, Hamasaki N, Suzuki Y, Kyogoku S, Hattori N, Aoki S.
Multiple sclerosis: Benefits of q-space imaging in evaluation of normal-appearing and periplaque white matter.
Magn Reson Imaging. 2014 Jul;32(6):625-9.
49Yamashita C, Tomiyama H, Funayama M, Inamizu S, Ando M, Li Y, Yoshino H, Araki T, Ichikawa T, Ehara Y, Ishikawa K, Mizusawa H, Hattori N.
Evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease.
Neurobiol Aging. 2014 Jul;35(7):1779.e17-21.
50Hattori N, Nomoto M; 6500-004 Study Group.
Sustained efficacy of apomorphine in Japanese patients with advanced Parkinson's disease.
Parkinsonism Relat Disord. 2014 Aug;20(8):819-23.
51Hattori N, Saiki S, Imai Y.
Regulation by mitophagy.
Int J Biochem Cell Biol.2014 Aug;53:147-50.
52Nishioka K, Tanaka R, Tsutsumi S, Yamashiro K, Nakahara M, Shimura H, Hattori N, Urabe T.
Cerebral dural sinus thrombosis associated with adenomyosis: a case report.
J Stroke Cerebrovasc Dis. 2014 Aug;23(7):1985-7.
53Amo T, Saiki S, Sawayama T, Sato S, Hattori N.
Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1.
Neurosci Lett.2014 Sep 19;580:37-40.
54Maraschi A, Ciammola A, Folci A, Sassone F, Ronzitti G, Cappelletti G, Silani V, Sato S, Hattori N, Mazzanti M, Chieregatti E, Mulle C, Passafaro M, Sassone J.
Parkin regulates kainate receptors by interacting with the GluK2 subunit.
Nat Commun. 2014 Oct 15;5:5182.
55Mitome-Mishima Y, Miyamoto N, Tanaka R, Shimosawa T, Oishi H, Arai H, Hattori N, Urabe T.
Adrenomedullin deficiency and aging exacerbate ischemic white matter injury after prolonged cerebral hypoperfusion in mice.
Biomed Res Int. 2014;2014:861632.
56Mizuno Y, Nomoto M, Hasegawa K, Hattori N, Kondo T, Murata M, Takeuchi M, Takahashi M, Tomida T; on behalf of the Rotigotine Trial Group.
Rotigotine vs ropinirole in advanced stage Parkinson's disease: A double-blind study.
Parkinsonism Relat Disord. 2014 Oct 12;20(12):1388-1393.
57Nakahara K, Ueda M, Yamada K, Koide T, Yoshimochi G, Funayama M, Kim JH, Yamakawa S, Mori A, Misumi Y, Uyama E, Hattori N, Ando Y.
Juvenile-onset parkinsonism with digenic parkin and PINK1 mutations treated with subthalamic nucleus stimulation at 45 years after disease onset.
J Neurol Sci. 2014 Oct 15;345(1-2):276-7.
58Shimada Y, Tanaka R, Shimura H, Yamashiro K, Urabe T, Hattori N.
Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice.
Neuroscience. 2014 Oct 10;278:113-21.
59Ueno Y, Okuzumi A, Watanabe M, Tanaka Y, Shimada Y, Yamashiro K, Tanaka R, Hattori N, Urabe T.
Cerebral small artery diseases may be associated with aortic arch calcification in stroke patients.
J Atheroscler Thromb. 2014;21(10):1011-21.
60Hatano T, Funayama M, Kubo S, Mata IF, Oji Y, Mori A, Zabetian CP, Waldherr SM, Yoshino H, Oyama G, Shimo Y, Fujimoto K, Oshima H, Kunii Y, Yabe H, Mizuno Y, Hattori N.
Identification of a Japanese family with LRRK2 p.R1441G-related Parkinson's disease.
Neurobiol Aging. 2014 Nov;35(11):2656.e17-23.
61Kurita N, Ueno Y, Watanabe M, Miyamoto N, Shimura H, Nonaka S, Tsutsumi S, Yasumoto Y, Hattori N, Urabe T.
Three cases of cervicocephalic artery dissection in an amusement park.
J Stroke Cerebrovasc Dis. 2014 Nov-Dec;23(10):e467-71.
62Kuroki T, Yamashiro K, Tanaka R, Hirano K, Shimada Y, Hattori N.
Vertebral artery dissection in patients with autosomal dominant polycystic kidney disease.
J Stroke Cerebrovasc Dis. 2014 Nov-Dec;23(10):e441-3.
63Miyazaki H, Oyama F, Inoue R, Aosaki T, Abe T, Kiyonari H, Kino Y, Kurosawa M, Shimizu J, Ogiwara I, Yamakawa K, Koshimizu Y, Fujiyama F, Kaneko T, Shimizu H, Nagatomo K, Yamada K, Shimogori T, Hattori N, Miura M, Nukina N.
Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum.
Nat Commun. 2014 Nov 21;5:5525.
64Nishioka K, Tanaka R, Shimura H, Hirano K, Hatano T, Miyakawa K, Arai H, Hattori N, Urabe T.
Quantitative evaluation of electroconvulsive therapy for Parkinson's disease with refractory psychiatric symptoms.
J Neural Transm. 2014 Nov;121(11):1405-10.
65Shiba-Fukushima K, Inoshita T, Hattori N, Imai Y.
Lysine 63-linked Polyubiquitination Is Dispensable for Parkin-mediated Mitophagy.
J Biol Chem. 2014 Nov 28;289(48):33131-6.
66Shiba-Fukushima K, Arano T, Matsumoto G, Inoshita T, Yoshida S, Ishihama Y, Ryu KY, Nukina N, Hattori N, Imai Y.
Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering.
PLoS Genet. 2014, 10:e1004861.
67Kashihara K, Kondo T, Mizuno Y, Kikuchi S, Kuno S, Hasegawa K, Hattori N, Mochizuki H, Mori H, Murata M, Nomoto M, Takahashi R, Takeda A, Tsuboi Y, Ugawa Y, Yamanmoto M, Yokochi F, Yoshii F, Stebbins GT, Tilley BC, Luo S, Wang L, LaPelle NR, Goetz CG; MDS-UPDRS Japanese Validation Study Group.
Official Japanese Version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale: validation against the original English version.
Mov Disord Clin Pract (Hoboken). 2014 Sep 1;1(3):200-212.
68Tanaka Y, Ueno Y, Shimada Y, Yamashiro K, Tanaka R, Urabe T, Hattori N.
Paradoxical Brain Embolism Associated with Kimura Disease Mimics Watershed Infarction.
J Stroke Cerebrovasc Dis. 2014 Nov 25. pii: S1052-3057(14)00479-0.
69Akamatsu H, Koh Y, Kenmotsu H, Naito T, Serizawa M, Kimura M, Mori K, Imai H, Ono A, Shukuya T, Taira T, Murakami H, Ohde Y, Endo M, Nakajima T, Takahashi T, Yamamoto N.
Multiplexed molecular profiling of lung cancer using pleural effusion.
J Thorac Oncol. 2014 Jul; 9(7): 1048-52.
70Akamatsu H, Mori K, Naito T, Imai H, Ono A, Shukuya T, Taira T, Kenmotsu H, Murakami H, Endo M, Harada H, Takahashi T, Yamamoto N.
Progression-free survival at 2 years is a reliable surrogate marker for the 5-year survival rate in patients with locally advanced non-small cell lung cancer treated with chemoradiotherapy.
BMC Cancer. 2014 Jan; 14: 18.
71Ando K, Takahashi F, Kato M, Kaneko N, Doi T, Ohe Y, Koizui F, Nishio K, Takahashi K.
Tocilizumab, a proposed therapy for the cachexia of interleukin6-expressing lung cancer.
PLoS One. 2014 Jul; 9(7): e102436.
72Ando K, Kaneko N, Doi T, Aoshima M, Takahashi K.
Prevalence and risk factors of aortic aneurysm in patients with chronic obstructive pulmonary disease.
J Thorac Dis. 2014 Oct; 6(10): 1388-95.
73Fujii M, Iwakami S, Itoigawa Y, Takahashi K.
Interesting radiological images of a tuberculous abscess.
Intern Med. 2014; 53(10): 1097-8.
74Haga T, Kataoka H, Ebana H, Otsuji M, Seyama K, Tatsumi K, Kurihara M.
Thoracic endometriosis-related pneumothorax distinguished from primary spontaneous pneumothorax in females.
Lung. 2014 Aug;192(4):583-7.
75Hasegawa S, Wakiguchi H, Okada S, Gui Kang Y, Fujii N, Hasegawa M, Hasegawa H, Ainai A, Atsuta R, Shirabe K, Toda S, Wakabayashi-Takahara M, Morishima T, Ichiyama T.
Cytokine profile of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during seasonal H1N1 infection.
Cytokine. 2014 Oct; 69(2): 206-10.
76Ito R, Gon Y, Nunomura S, Atsuta R, Harada N, Hattori T, Maruoka S, Okayama Y, Ra C, Hashimoto S.
Development of assay for determining free IgE levels in serum from patients treated with omalizumab.
Allergol Int. 2014 May; 63 Suppl 1:37-47.
77Iwakami S, Ihara H, Fujii M, Takahashi K.
A pulmonary nodule exhibiting temporary spontaneous regression.
Intern Med. 2014; 53(4): 337-8
78Imai H, Takahashi T, Mori K, Ono A, Akamatsu H, Shukuya T, Taira T, Kenmotsu H, Naito T, Murakami H, Endo M, Nakajima T, Yamamoto N.
Individual-level data on the relationships of progression-free survival, post-progression survival, and tumor response with overall survival in patients with advanced non-squamous non-small cell lung cancer.
Neoplasma. 2014; 61(2): 233-40.
79Ishida K, Sekizuka T, Hayashida K, Matsuo J, Takeuchi F, Kuroda M, Nakamura S, Yamazaki T, Yoshida M, Takahashi K, Nagai H, Sugimoto C, Yamaguchi H.
Amoebal endosymbiont Neochlamydia genome sequence illuminates the bacterial role in the defense of the host amoebae against Legionella pneumophila.
PLoS One. 2014 Apr; 9(4): e95166.
80Kamachi F, Harada N, Usui Y, Sakanishi T, Ishii N, Okumura K, Miyake S, Akiba H.
OX40 ligand regulates splenic CD8-dendritic cell-induced Th2 responses in vivo. 
Biochemical and Biophysical Research Communications. 2014; 444(2): 235-240.
81Kanaji N, Basma H, Nelson A, Farid M, Sato T, Nakanishi M, Wang X, Michalski J, Li Y, Gunji Y, Feghali-Bostwick C, Liu X, Rennard SI.
Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes.
Am J Physiol Lung Cell Mol Physiol. 2014 Sep; 307(5): L364-73.
82Kato M, Shukuya T, Takahashi F, Mori K, Suina K, Asao T, Kanemaru R, Honma Y, Muraki K, Sugano K, Shibayama R, Koyama R, Shimada N, Takahashi K.
Pemetrexed for advanced non-small cell lung cancer patients with interstitial lung disease.
BMC Cancer. 2014 Jul; 14(1): 508.
83Ko R, Kenmotsu H, Hisamatsu Y, Akamatsu H, Omori S, Nakashima K, Oyakawa T, Wakuda K, Shukuya T, Ono A, Imai H, Taira T, Naito T, Murakami H, Mori K, Endo M, Ohde Y, Takahashi K, Takahashi T.
The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.
Int J Clin Oncol. 2014 Oct; 25.
84Koike K, Ishigami A, Sato Y, Hirai T, Yuan Y, Kobayashi E, Tobino K, Sato T, Sekiya M, Takahashi K, Fukuchi Y, Maruyama N, Seyama K.
Vitamin C prevents cigarette smoke-induced pulmonary emphysema in mice and provides pulmonary restoration.
Am J Respir Cell Mol Biol. 2014; 50(2): 347-57.
85Kumasaka T, Hayashi T, Mitani K, Kataoka H, Kikkawa M, Tobino K, Kobayashi E, Gunji Y, Kunogi M, Kurihara M, Seyama K.
Characterization of pulmonary cysts in Birt-Hogg-Dubé syndrome: histopathological and morphometric analysis of 229 pulmonary cysts from 50 unrelated patients.
Histopathology. 2014 Jul; 65(1): 100-10.
86Kuriyama S, Morio Y, Toba M, Nagaoka T, Takahashi F, Iwakami S, Seyama K, Takahashi K.
Genistein attenuates hypoxic pulmonary hypertension via enhanced nitric oxide signaling and the erythropoietin system.
Am J Physiol Lung Cell Mol Physiol. 2014 Jun; 306(11): L996-L1005.
87Li YJ, Kanaji N, Wang XQ, Sato T, Nakanishi M, Kim M, Michalski J, Nelson AJ, Farid M, Basma H, Patil A, Toews ML, Liu X, Rennard SI.
Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition.
Prostaglandins Other Lipid Mediat. 2014 Oct; 31: 116-117, C:1-9.
88Mizugaki H, Fujiwara Y, Yamamoto N, Yagishita S, Kitazono S, Tanaka A, Horinouchi H, Kanda S, Nokihara H, Tsuta K, Asamura H, Tamura T.
Adjuvant chemotherapy in patients with completely resected small cell lung cancer: a retrospective analysis of 26 consecutive cases.
Jpn J Clin Oncol. 2014 Sep; 44(9): 835-40.
89Murakami A, Takahashi F, Nurwidya F, Kobayashi I, Minakata K, Hashimito M, Nara T, Kato M, Tajima K, Shimada N,Iwakami S, Moriyama M, Moriyama H, Koizumi F, Takahashi K.
Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.
PLoS One. 2014 Jan; 9(1): e86459. 
90Murakami A, Hayashi T, Terao Y, Mori T, Kumasaka T, Seyama K, Takahashi K.
Cystic, nodular and cavitary metastases to the lungs in a patient with endometrial stromal sarcoma of the uterus.
Intern Med. 2014; 53(9): 1001-5.
91Nakashita T, Ando K, Kaneko N, Takahashi K, Motojima S.
Potential risk of TNF inhibitors on the progression of interstitial lung disease in patients with rheumatoid arthritis.
BMJ Open. 2014; 4: e005615.
92Nakagawa N, Saito Y, Sasaki M, Tsuda Y, Mochizuki H, Takahashi H.
Comparison of clinical profile in elderly patients with nursing and healthcare-associated pneumonia and those with community-acquired pneumonia.
Geriatr Gerontol Int. 2014 Apr;14(2):362-71.
93Nurwidya F, Takahashi F, Kobayashi I, Murakami A, Kato M, Minakata K, Nara T, Hashimoto M, Yagishita Y, Baskoro H, Hidayat M, Shimada N, Takahashi K.
Treatment with insulin-like growth factor 1 receptor inhibitor reverses hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer
Biochem Biophys Res Commun. 2014; 12: 455(3-4):332-8.
94Sato T, Suzuki Y, Mori T, Maeda M, Abe M, Hino O, Takahashi K.
Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma.
Cancer Med. 2014 Oct; 3(5):1377-84.
95Shiota S, Inoue Y, Takekawa H, Kotajima M, Nakajyo M, Usui C, Yoshioka Y, Koga T, Takahashi K.
Effect of continuous positive airway pressure on regional cerebral blood flow during wakefulness in obstructive sleep apnea.
Sleep Breath. 2014; 18(2): 289-95.
96Shukuya T, Serizawa M, Watanabe M, Akamatsu H, Abe M, Imai H, Tokito T, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Ohde Y, Nakajima T, Yamamoto N, Koh Y.
Identification of actionable mutations in malignant pleural mesothelioma.
Lung Cancer. 2014 Oct; 86(1): 35-40.
97Shukuya T, Takahashi T, Imai H, Tokito T, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Murakami H, Endo M, Yamamoto N.
Comparison of cisplatin plus pemetrexed and cisplatin plus gemcitabine for the treatment of malignant pleural mesothelioma in Japanese patients.
Respir Investig. 2014 Mar; 52(2): 101-6.
98Suina K, Hayashi T, Mitani K, Suzuki K, Takahashi K, Seyama K.
What׳s the role of sirolimus on the treatment of lymphangioleiomyomatosis (LAM)?: Merely tuning up of LAM-associated dysfunctional lymphatic vessels rather than cytoreduction?
Respir Investig. 2014 Jul; 52(4): 274-6.
99Tokito T, Shukuya T, Akamatsu H, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Mori K, Yamamoto N.
Toxicity and efficacy of chemotherapy for non-small cell lung cancer with cavitary lesions.
Respir Investig. 2014 May; 52(3):184-9.
100Wang XQ, Mao LJ, Fang QH, Kobayashi T, Kim HJ, Sugiura H, Kawasaki S, Togo S, Kamio K, Liu X, Rennard SI.
Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway.
Prostaglandins Other Lipid Mediat. 2014 Jan; 108: 23-30.
101Yagishita S, Horinouchi H, Taniyama K, Nakamichi S, Kitazono S, Mizugaki H, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Sumi M, Shiraishi K, Kohno T, Furuta K, Tsuta K, Tamura T.
Epidermal Growth Factor Receptor Mutation Is Associated With Longer Local Control After Definitive Chemoradiotherapy in Patients With Stage III Nonsquamous Non-Small-Cell Lung Cancer.
Int J Radiat Oncol Biol Phys. 2014 Oct; S0360-3016(14)04051-6.
102Yagishita S, Horinouchi H, Yorozu T, Kitazono S, Mizugaki H, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Mori T, Tsuta K, Sumi M, Tamura T.
Secondary osteosarcoma developing 10 years after chemoradiotherapy for non-small-cell lung cancer.
Jpn J Clin Oncol. 2014 Feb; 44(2): 191-4.
103Suzuki N, Numakawa T Joshua Chou J, de Vega, S, Mizuniwa C, Sekimoto K, Adachi N, Kunugi N, Arikawa-Hirasawa E, Yamada Y, Akazawa C.
Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling.
The FASEB Journal article fj.13-241034. Published online. 2014 28:1386-97.
104Kerever A Mercier F, Nonaka R, de Vega S, Oda Y, Zalc B, Okada Y, Hattori N, Yamada Y, Arikawa-Hirasawa,
Perlecan is required for FGF-2 signaling in the neural stem cell niche.
Stem Cell Res. 2014 12:492-505.
105Furuya N, Ikeda SI, Sato S, Soma S, Ezaki J, Trejo JA, Takeda-Ezaki M, Fujimura T, Arikawa-Hirasawa E, Tada N, Komatsu M, Tanaka K, Kominami E, Hattori N, Ueno T.
PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation.
Autophagy. 10:631-41. 2014 Jan 21.
106de Vega S, Suzuki N, Nonaka R, Sasaki T, Forcinito P, Arikawa-Hirasawa E, Yamada Y.
A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture.
Arch Biochem Biophys. 1;545:148-53. 2014
107Ning L, Kurihara H, de Vega S,* Ichikawa-Tomikawa n, Xu Z,Nonaka R, Kazuno S, Yamada Y, Miner JH, Arikawa-HirasawA E,
Laminin α1 regulates age-related mesangial cell proliferation and mesangial matrix accumulation through the TGFβ pathway
The American Journal of Pathology . 184:1683-94.2014.
108Ito T, Sato K, Maekawa H, Sakurada M, Orita H, Shimada K, Daida H, Wada R, Abe M, Hino O, Kajiyama Y.
Elevated levels of serum fatty acid synthase in patients with gastric carcinoma.
Oncol Lett. 7:616-620;2014.
109Miyazaki T, Shimada K, Hki M, Kume A, Kitamura Y, Oshida K, Yanagisawa N, Kiyanagi T, Matsumori R, Daida H.
High hexacosanoic acid levels are associated with coronary artery disease.
Atherosclerosis. 223:429-433;2014.
110Nishizaki Y, Shimada K, Tani S, Ogawa T, Ando J, Takahashi M, Yamamoto M, Shinozaki T, Miyauchi K, Nagao K, Hirayama A, Yoshimura M, Komuro I, Nagai R, Daida H.
Significance of Imbalance in the Ratio of Serum n-3 to n-6 Polyunsaturated Fatty Acids in Patients with Acute Coronary Syndrome,
Am J Cardiol. 113:441-445;2014.
111Yokoi H, Nohara R, Daida H, Hata M, Kaku K, Kawamori R, Kishimoto J, Kurabayashi M, Masuda I, Sakuma I, Yamazaki T, Yoshida M.
Change in carotid intima-media thickness in a high-risk group of patients by intensive lipid-lowering therapy with rosuvastatin.
Int Heart J. 2014 Mar 28;55(2):146-52
112Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Familial hypercholesterolemia.
J Atheroscler Thromb. 2014 Mar 27;21(3):289.
113Daida H, Teramoto T, Kitagawa Y, Matsushita Y, Sugihara M.
The relationship between low-density lipoprotein cholesterol levels and the incidence of cardiovascular disease in high-risk patients treated with pravastatin: main results of the APPROACH-J study.
Int Heart J. 2014;55(1):39-47.
114Ohmura T, Iwama Y, Kasai T, Kato T, Suda S, Takagi A, Daida H.
Impact of predischarge nocturnal pulse oximetry (sleep-disordered breathing) on postdischarge clinical outcomes in hospitalized patients with left ventricular systolic dysfunction after acute decompensated heart failure.
Am J Cardiol. 2014 Feb 15;113(4):697-700.
115Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K, Harada-Shiba M, Arai H, Bujo H, Nohara A, Ohta T, Oikawa S, Okada T, Wakatsuki A.
Familial hypercholesterolemia.
J Atheroscler Thromb. 2014 Jan 23;21(1):6-10.
116Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
The elderly.
J Atheroscler Thromb. 2014 Mar 27;21(3):180-5.
117Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Cerebrovascular diseases.
J Atheroscler Thromb. 2014 Mar 27;21(3):175-9.
118Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Chronic kidney disease.
J Atheroscler Thromb. 2014 Mar 27;21(3):173-4.
119Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Diabetes mellitus. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version.
J Atheroscler Thromb. 2014;21(2):93-8.
120Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Coronary artery disease. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version.
J Atheroscler Thromb. 2014;21(2):86-92.
121Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Other types of primary hyperlipoproteinemia(hyperlipidemia). Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version.
J Atheroscler Thromb. 2014;21(2):82-5.
122Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Metabolic syndrome.
J Atheroscler Thromb. 2014 Jan 23;21(1):1-5.
123Chiang SJ, Daimon M, Ishii K, Kawata T, Miyazaki S, Hirose K, Ichikawa R, Miyauchi K, Yeh MH, Chang NC, Daida H.
Assessment of elevation of and rapid change in left ventricular filling pressure using a novel global strain imaging diastolic index.
Circ J. 2014;78(2):419-27.
124Ueno Y, Yamashiro K, Tanaka Y, Watanabe M, Shimada Y, Kuroki T, Miyamoto N, Daimon M, Tanaka R, Miyauchi K, Daida H, Hattori N, Urabe T.
Rationale and design of the EPISTEME trial: efficacy of post-stroke intensive rosuvastatin treatment for aortogenic embolic stroke.
Cardiovasc Drugs Ther. 2014 Feb;28(1):79-85
125Naito R, Miyauchi K, Ogita M, Kasai T, Kawaguchi Y, Tsuboi S, Konishi H, Okazaki S, Kurata T, Daida H.
Impact of admission glycemia and glycosylated hemoglobin A1c on long-term clinical outcomes of non-diabetic patients with acute coronary syndrome.
J Cardiol. 2014 Feb;63(2):106-11.
126Ogita M, Miyauchi K, Miyazaki T, Naito R, Konishi H, Tsuboi S, Dohi T, Kasai T, Yokoyama T, Okazaki S, Kurata T, Daida H.
Low high-density lipoprotein cholesterol is a residual risk factor associated with long-term clinical outcomes in diabetic patients with stable coronary artery disease who achieve optimal control of low-density lipoprotein cholesterol.
Heart Vessels. 2014 Jan;29(1):35-41.
127Suyama M, Koik M, Asaoka D, Mori H, Oguro M, Ueno T, Nagahara A, Watanabe S, Uchiyama U (2014)
Increased immunoreactivity of cathepsins in the rat esophagus under chronic acid reflux esophagitis.
J Histochem Cytochem 62:645-660
128Sakuraba M, Murata J, Teruyama R, Kamiya K, Yamaguchi J, Okano Y, Uchiyama Y, Ikeda K (2014)
Spatotemporal expression of TRPM4 in the mouse cochlea.
J Neurosci Res 92:1409-1418
129Ueshima S, Nishida T, Koike M, Matsuda H, Sawa Y, Uchiyama Y (2014)
Nirtic oxide-mediated injury of interstitial cells of Cajal and intestinal dysmotility under endotoxemia.
Biomed Res 35:251-262
130Bartolomé A, Kimura-Koyanagi M, Asahara S, Guillén C, Teruyama K, Inoue H, Shimizu S, Kanno A, García-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y (2014)
Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic impairment.
Diabetes
131Nakafuku-Fukuda M, Hirata T, Keto Y, Yamano M, Yokoyama T, Uchiyama Y (2014)
Inhibitory effect of the selective secretion 5-HT receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.
Eur J Pharmacol 731:88-92 doi: 10.1016/j.ejphar.2014.02.040.
132Yamanaka T, Tosaki A, Kurosawa M, Matsumoto G, Koike M, Uchiyama Y, Maity SN, Shimogori T, Hattori N, Nukina N (2014)
NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.
Nat Commun doi:10.1038/ncomms4354
133Yokono M, Takasu T, Hayashizaki Y, Mitsuoka K, Kihara R, Muramatsu Y, Miyoshi S, Tahara A, Kurosaki E, Li Q, Tomiyama H, Sasamata M, Shibasaki M, Uchiyama Y (2014)
SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats.
Eur J Pharmacol 727-66-74 doi: 10.1016/j.erphar.2014.01.004
134Awazawa M, Futami T, Sakada M, Kaneko K, Ohsugi M, Nakaya K, Terai A, Suzuki R, Koike M, Uchiyama Y, Kadowaki T, Ueki K (2014)
Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus.
Mol Cell Biol 34:1290-1299 doi:10.1128/MCB.01647-13
135Kashima J, Shintani-Ishida K, Nakajima M, Maeda H, Unuma K, Uchiyama Y, Yoshida K (2014)
Immunocytochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.
Hepatol Res, 44:779-787, DOI: 10.1111/hepr.12183

英文原著(2013年)

1Bian Z, Furuya N, Zheng D-M, Oliva Trejo JA, Tada N, Ezaki J, Ueno T.
Ferulic acid induces mTor inactivation in cultured mammalian cells.
Biol Pharm Bull. 2013; 36(1): 120-124.
2Kawano S, Lin Q, Amano H, Kaneko T, Nishikawa K, Tsurui H, Tada N, Nishimura H, Takai T, Shirai T, Takasaki Y, Hirose S.
Phenotype conversion from rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcγRIIB-deficient C57BL/6 mice.
Eur J Immunol. 2013 Mar; 43(3): 770-778.
3Koike M, Tanida I, Nanao T, Tada N, Iwata J-I, Ueno T, Kominami E and Uchiyama Y.
Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons.
PLOS ONE. 2013 May; 8(5): e63568.
4Miyajima M, Nakajima M, Motoi Y, Moriya M, Sugano H, Ogino I, Nakamura E, Tada N, Kunichika M, Arai H.
Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex.
PLOS ONE. 2013 Sep; 8(9): e74453.
5Miyajima M, Nakajima M, Ogino I, Miyata H, Motoi Y, Arai H:
Soluble amyloid precursor protein α in the cerebrospinal fluid as a diagnostic and prognostic biomarker for idiopathic normal pressure hydrocephalus.
Eur J Neurol. 20(2): 236-242,2013
6Watanabe M, Miyajima M, Ogino I, Nakajima M, Arai H:
Cerebellar Purkinje Cells Exhibit Increased Expression of HMGB-1 and Apoptosis in Congenital Hydrocephalic H-Tx Rats.
Neurosurgery. 72(3): 459-467, 2013
7Miyajima M, Nakajima M, Motoi Y, Moriya M, Sugano H, Ogino I, Nakamura E, Tada N, Kunichika M, Arai H :
Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex.
PLoS One. 2013 Sep 18;8(9):e74453
8Hoshi K, Kariya Y, Nara K, Ito H, Matsumoto K, Nagae M, Yamaguchi Y, Nakajima M, Miyajima M, Arai H, Kuno A, Narimatsu H, Shirotani K, Hashimoto Y:
Lectin-dependent inhibition of antigen-antibody reaction: application for measuring α2,6-sialylated glycoforms of transferrin.
J Biochem. 2013 Sep;154(3):229-32.
9Tsutsumi S, Ogino I, Miyajima M, Ikeda T, Shindo N, Yasumoto Y, Ito M, Arai H.
Genomic causes of multiple cerebral cavernous malformations in a Japanese population.
J Clin Neurosci. 2013 May;20(5):667-9.
10Shimoji K, Kimura T, Kondo A, Tange Y, Miyajima M, Arai H:
Genetic studies of myelomeningocele.
Childs Nerv Syst. 2013 Sep;29(9):1417-25.
11Nakanishi A, Fukunaga I, Hori M, Masutani Y, Takaaki H, Miyajima M, Aoki S:
Microstructural changes of the corticospinal tract in idiopathic normal pressure hydrocephalus: a comparison of diffusion tensor and diffusional kurtosis imaging.
Neuroradiology. 2013 Aug;55(8):971-6.
12Shibata N, Nagata T, Shinagawa S, Ohnuma T, Shimazaki H, Komatsu M, Kuerban B Tomson K, Nakayama K, Yamada H, Arai H.
Genetic association between APOA1 and APOD polymorphisms and Alzheimer's disease in a Japanese population.
J Neural Transm.2013:120(11):1599-1603.
13Nagata T, Shibata N, Shinagawa S, Nakayama R, Kuerban B, Ohnuma T, Arai H, Nakayama K, Yamada H.
Genetic Association between Neurotrophin-3 Polymorphisms and Alzheimer's Disease in Japanese Patients.
Dement Geriatr Cogn Dis Extra.2013:3:272-280.
14Ohnuma T, Takebayashi Y, Higashiyama R, Shibata N, Arai H.
Low-dose lamotrigine augmentation therapy improves residual symptoms in treatment-resistant schizophrenia: A report of five cases Asia-Pacific.
Psychiatry.2013.5:336–343.
15Nobuto Shibata, Yumiko Motoi, Hiroyuki Tomiyama, Tohru Ohnuma, Bolati Kuerban, Katrin Tomson, Miwa Komatsu, Hiromi Shimazaki, Nobutaka Hattori, Heii Arai.
Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer’s Disease and Parkinson’s Disease with Dementia.
Dement Geriatr Cogn Dis Extra.2013:May 18;3(1):161-7.
16Nagata T, Shinagawa S, Kuerban B, Shibata N, Ohnuma T, Arai H, Nakayama K,YamadaH.
Age-Related Association between Apolipoprotein E ε4 and Cognitive Function in Japanese Patients with Alzheimer's Disease. 
Dement Geriatr Cogn Dis Extra. 2013:Jan;3(1):66-73.
17Bian Z, Furuya N, Zheng D-M, Oliva Trejo JA, Tada N, Ezaki J, Ueno T.
Ferulic acid induces mTor inactivation in cultured mammalian cells.
Biol Pharm Bull. 2013; 36(1): 120-124.
18Kawano S, Lin Q, Amano H, Kaneko T, Nishikawa K, Tsurui H, Tada N, Nishimura H, Takai T, Shirai T, Takasaki Y, Hirose S.
Phenotype conversion from rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcγRIIB-deficient C57BL/6 mice.
Eur J Immunol. 2013 Mar; 43(3): 770-778.
19Koike M, Tanida I, Nanao T, Tada N, Iwata J-I, Ueno T, Kominami E and Uchiyama Y.
Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons.
PLOS ONE. 2013 May; 8(5): e63568.
20Miyajima M, Nakajima M, Motoi Y, Moriya M, Sugano H, Ogino I, Nakamura E, Tada N, Kunichika M, Arai H.
Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex.
PLOS ONE. 2013 Sep; 8(9): e74453.
21Hirose S, Watanabe T, Wada H, Imai Y, Machida T, Shirouzu I, Miyashita Y, Konishi S.
Functional relevance of micromodules in the human association cortex delineated with high-resolution fMRI.
Cerebral Cortex, 23, 2863-2871, 2013
22Hirose S, Kimura H. M, Jimura K, Kunimatsu A, Abe O, Ohtomo K, Miyashita Y, Konishi S.
Dissociable temporo-parietal memory networks revealed by functional connectivity during episodic retrieval.
PLoS ONE, 8, e71210, 2013
23Watanabe T, Hirose S, Wada H, Imai Y, Machida T, Shirouzu I, Konishi S, Miyashita Y, Masuda N.
A pairwise maximum entropy model accurately describes resting-state human brain networks.
Nature Communications, 4, 1370, 2013
24Uchimura M, Kitazawa S.
Cancelling prism adaptation by a shift of background: a novel utility of allocentric coordinates for extracting motor errors.
J Neurosci. 33: 7595-7602, 2013.
25Mitani A, Sasaki R, Oizumi M, Uka T.
A leaky-integrator model as a control mechanism underlying flexible decision making during task switching.
PLoS ONE. 8: e59670, 2013.
26Ando K ,Takahashi F, Motojima S, Nakashima K, Kaneko N, Hoshi K, Takahashi K.
Possible Role for Tocilizumab, an Anti-Interleukin-6 Receptor Antibody, in Treating CancerCachexia.
Journal of Clinical Oncology. 2013; 31(6): 69-72.
27Ando K, Kurihara M, Kataoka H, Ueyama M, Togo S, Sato T, Doi T, Iwakami S, Takahashi K, Seyama K, Mikami M.
The efficacy and safety of low-dose sirolimus in lymphangioleiomyomatosis.

Respiratory Investigation. 2013; 51(3): 175-83.
28Ando K, Motojima S, Doi T, Nagaoka T, Kaneko N, Aoshima M, Takahashi K.
Effect of glucocorticoid monotherapy on pulmonary function and survival in Japanese patients with scleroderma-related interstitial lung disease.
Respiratory Investigation. 2013; 51(2): 69-75.
29Ando K, Sekiya M, Tobino K, Takahashi K.
Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema.
Lung.2013; 19(6): 585-91.
30Babaei Jandaghi A, Daliri S, Kikkawa M, Khaledi M, Soleimanifar N, Alizadeh A, Habibzadeh M, Haghi-Ashtiani MT, Seyama K, Rezaei N.
The discovery of a Persian family with a form of Birt-Hogg-Dubé syndrome lacking the typical cutaneous stigmata of the syndrome.
Clin Imaging. 2013; 37: 111-115.
31Harada M, Akimoto K, Otaka M, Sato K, Oda H, Otsuki M, Takahashi K, Kishiro M, Shimizu T.
Thrombolytic therapy in Kawasaki disease: a report of four cases.
Pediatr Int. 2013 Oct; 55(5): e111-5.
32Hoshika Y, Hamamoto T, Sato K, Eto H, Kuriyama S, Yoshimi K, Iwakami S, Takahashi K, Seyama K.
Prevalence and clinical features of lymphedema in patients with lymphangioleiomyomatosis.
Respir Med. 2013; 107(8): 1253-1259.
33Imai H, Shukuya T, Yoshino R, Muraki K, Mori K, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Murakami H, Tomizawa Y, Takahashi T, Takahashi K, Saito R, Yamamoto N.
Efficacy and safety of platinum combination chemotherapy re-challenge for relapsed patients with non-small-cell lung cancer after postoperative adjuvant chemotherapy of cisplatin plus vinorelbine.
Chemotherapy. 2013; 59(4): 307-13.
34Iwakami S, Fujii M, Ishiwata T, Iwakami N, Hara M, Ihara H, Wada R, Tsutsumi T, Seyama K, Takahashi K.
Small-cell Lung Cancer Exhibiting Spontaneous Regression.
Reprinted from Internal Medicine. 2013 Oct; 52(19): 2249-2252.
35Ishiwata T, Seyama K, Hirao T, Shimada K, Morio Y, Miura K, Kume A, Takagi H, Takahashi K.
Improvement in skin color achieved by smoking cessation.
Int J Cosmet Sci. 2013; 35(2): 191-5.
36Kato M, Tobino K, Fujimoto Y, Kobayashi I, Sugano K, Tokuda H, Ienaga H, Takahashi K.
Pneumocystis pneumonia induced by treatment with low-dose tacrolimus and methylprednisolone in a patient with rheumatoid arthritis: a case report.
BMC Res Notes. 2013; 6(1): 498.
37Mochizuki H, Nanjo Y, Takahashi H.
Better adherence to a transdermal tulobuterol patch than inhaled salmeterol in elderly COPD patients.
Geriat Geront Int. 2013; 398-404.
38Mori T, Tajima K, Hirama M, Sato T, Kido K, Iwakami S, Sasaki S, Iwase A, Shiomi K, Maeda M, Hino O, Takahashi K.
The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma.
J Thorac Dis. 2013; 5(2): 145-148.
39Nagahama KY, Togo S, Holz O, Magnussen H, Liu X, Seyama K, Takahashi K, Rennard SI.
Oncostatin M modulates fibroblast function via signal ttransducers and activators of transcription proteins-3.
Am J Respir Cell Mol Biol. 2013; 49(4): 582-591.
40Nagashima O, Matsuno K, Tominaga S, Takahashi K.
Esophageal diverticulum with idiopathic pulmonary upper lobe fibrosis.
Intern Med. 2013; 52(1): 159..
41Nagashima O, Ohashi R, Yoshioka Y, Inagaki A, Tajima M, Koinuma Y, Iwakami S, Iwase A, Sasaki S, Tominaga S, Takahashi K.
High prevalence of gene abnormalities in young patients with lung cancer.
J Thorac Dis. 2013; 5(1): 27-30.
42Nanjo Y, Ishii Y, Kimura S, Fukami T, Mizoguchi M, Suzuki T, Tomono K, Akasaka Y, Ishii T, Takahashi K, Tateda K, Yamaguchi K.
Effects of slow-releasing colistin microspheres on emdotoxin-induced sepsis.
J Infect Chemother. 2013; 19(4): 683-90.
43Sasaki M,Mochizuki H,Takahashi H.
Bronchoesoph ageal fistula developing shortly after initiation of antituberculous chemotherapy.
Internal Medicine. 2013; 52: 376-380.
44Sekiya M, Yoshimi K, Muraki K, Suzuki K, Dambara T, Toshimasa U, Takahashi K.
Solitary Fibrous Tumor of the Pleura: Ultrasonographic Imaging Findings of Three Cases.
Respiratory Investigation. 2013; 51(3): 200-204.
45Shiota S, Takekawa H, Matsumoto S,Takeda K, Nurwidya F, Yoshioka Y, Takahashi F, Hattori N, Tabira T, Mochizuki H, Takahashi K.
Chronic Intermittent Hypoxia/Reoxygenation Facilitate Amyloid-β Generation in Mice.
Journal of Alzheimer’s Disease 2013; 37: 325-333.
46Shukuya T, Takahashi T, Harada H, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Murakami H, Endo M, Takahashi K, Yamamoto N.
Chemoradiotherapy for limited-desease small-cell lung cancer in elderly patients aged 75 years or older.
Jpn J Clin Oncol. 2013; 43(2): 176-183.
47Suzuki K, Seyama K, Hayashi T, Yamashiro Y, Shiraishi A, Kuwatsuru R.
Reversed halo sign in tuberous sclerosis complex.
Case Rep Radiol. 2013; 428501.
48Togo S, Polanska U, Horimoto Y, Orimo A.
Cancer-associated fibroblasts are promising thrapeutic target. 
Cancers Jun. 2013; 5: 149-169.
49Douet V, Arikawa-Hirasawa E, Mercier F
Fractone-heparan sulfates mediate FGF-2 stimulation of cell proliferation in the adult subventricular zone.
Cell Prolif. 46:137-45. 2013 IF:3.116
50Nakazawa N, Miyahara K, Okawada M, Yamataka A, Suzuki R, Akazawa C, Tomikawa-Ichikawa N, Arikawa-Hirasawa E.
Laminin-1 promotes enteric nervous system development in mouse embryo.
Pediatr Surg Int. 29:1205-8. 2013 IF:0.995
51Nishizaki Y, Yamagami S, Myojin M, Sesoko M, Yamashita H, Suzuki R, Daida H.
A murmur-free giant myxoma discovered incidentally on abdominal ultrasonography.
Intern Med. 2013;52(22):2529-31.
52Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Treatment A) lifestyle modification: executive summary of the Japan Atherosclerosis Society(JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version.
J Atheroscler Thromb. 2013;20(12):835-49.
53Hirayama A, Tanahashi N, Daida H, Ishiguro N, Chachin M, Sugioka T, Kawai S; all ACCEPT study investigators in Japan.
Assessing the cardiovascular risk between celecoxib and nonselective nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis and osteoarthritis.
Circ J. 2013 Dec 25;78(1):194-205.
54Nishizaki Y, Daimon M, Miyazaki S, Suzuki H, Kawata T, Miyauchi K, Chiang SJ, Makinae H, Shinozaki T, Daida H.
Clinical factors associated with classical symptoms of aortic valve stenosis.
J Heart Valve Dis. 2013 May;22(3):287-94.
55Yang B, Daimon M, Ishii K, Kawata T, Miyazaki S, Hirose K, Ichikawa R, Chiang SJ, Suzuki H, Miyauchi K, Daida H.
Prediction of coronary artery stenosis at rest in patients with normal left ventricular wall motion. Segmental analyses using strain imaging diastolic index.
Int Heart J. 2013;54(5):266-72.
56Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Treatment B) drug therapy: executive summary of the Japan Atherosclerosis Society(JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version.
J Atheroscler Thromb. 2013;20(12):850-60.
57Kawata T, Daimon M, Hasegawa R, Toyoda T, Sekine T, Himi T, Uchida D, Miyazaki S, Hirose K, Ichikawa R, Maruyama M, Suzuki H, Daida H.
Prognostic value of coronary flow reserve assessed by transthoracic Doppler echocardiography on long-term outcome in asymptomatic patients with type 2 diabetes without overt coronary artery disease.
Cardiovasc Diabetol. 2013 Aug 27;12:121.
58Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Other high-risk conditions.
J Atheroscler Thromb. 2013 Nov 25;20(11):785-9.
59Ohno I, Hayashi H, Aonuma K, Horio M, Kashihara N, Okada H, Komatsu Y, Tamura S, Awai K, Yamashita Y, Kuwatsuru R, Hirayama A, Saito Y, Murohara T, Tamaki N, Sato A, Takayama T, Imai E, Yasuda Y, Koya D, Tsubakihara Y, Horie S, Korogi Y, Narumi Y, Hayakawa K, Daida H, Node K, Kubota I; Japanese Society of Nephrology, Japan Radiological Society, and Japanese Circulation Society Science Advisory and Coordinating Committee.
Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version : JSN, JRS, and JCS Joint Working Group.
Clin Exp Nephrol. 2013 Aug;17(4):441-79.
60Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Absolute risk of cardiovascular disease and lipid management targets.
J Atheroscler Thromb. 2013;20(9):689-97.
61Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Cardiovascular disease risk factors other than dyslipidemia. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan - 2012 version.
J Atheroscler Thromb. 2013;20(10):733-42.
62Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K.
Diagnostic criteria for dyslipidemia.
J Atheroscler Thromb. 2013 Aug 26;20(8):655-60.
63Ohno I, Hayashi H, Aonuma K, Horio M, Kashihara N, Okada H, Komatsu Y, Tamura S, Awai K, Yamashita Y, Kuwatsuru R, Hirayama A, Saito Y, Murohara T, Tamaki N, Sato A, Takayama T, Imai E, Yasuda Y, Koya D, Tsubakihara Y, Horie S, Korogi Y, Narumi Y, Hayakawa K, Daida H, Node K, Kubota I; Japanese Society of Nephrology; Japan Radiological Society; Japanese Circulation Society.
Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version. JSN, JRS, and JCS Joint Working Group.
Jpn J Radiol. 2013 Aug;31(8):546-84.
64Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K; Japan Atherosclerosis Society (JAS).
Comprehensive risk management for the prevention of cardiovascular disease: executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan -- 2012.
J Atheroscler Thromb. 2013 Jul 30;20(7):603-15.
65Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, I ida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K; Japan Atherosclerosis Society.
Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan -2012 version.
J Atheroscler Thromb. 2013;20(6):517-23.
66Daida H, Miyauchi K, Ogawa H, Yokoi H, Matsumoto M, Kitakaze M, Kimura T, Matsubara T, Ikari Y, Kimura K, Tsukahara K, Origasa H, Morino Y, Tsutsui H, Kobayashi M, Isshiki T; PACIFIC investigators.
Management and two-year long-term clinical outcome of acute coronary syndrome in Japan: prevention of atherothrombotic incidents following ischemic coronary attack (PACIFIC) registry.
Circ J. 2013;77(4):934-43.
67Nohara R, Daida H, Hata M, Kaku K, Kawamori R, Kishimoto J, Kurabayashi M, Masuda I, Sakuma I, Yamazaki T, Yokoi H, Yoshida M; Justification For Atherosclerosis Regression Treatment (JART) Investigators.
Effect of long-term intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness--Justification for Atherosclerosis Regression Treatment (JART) extension study.
Circ J. 2013;77(6):1526-33.
68Nishizaki Y, Yamagami S, Joki Y, Takahashi S, Sesoko M, Yamashita H, Yokoyama T, Uehara Y, Daida H.
Japanese features of native valve endocarditis caused by coagulase-negative staphylococci: case reports and a literature review.
Intern Med. 2013;52(5):567-72.
69Ichikawa R, Daimon M, Miyazaki T, Kawata T, Miyazaki S, Maruyama M, Chiang SJ, Suzuki H, Ito C, Sato F, Watada H, Daida H.
Influencing factors on cardiac structure and function beyond glycemic control in patients with type 2 diabetes mellitus.
Cardiovasc Diabetol. 2013 Feb 27;12:38.
70Daida H, Iwase T, Yagi S, Ando H, Nakajima H.
Effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity in Japanese dyslipidemic patients, with exploratory analysis of a PLA2G7 gene polymorphism of Val279Phe.
Circ J. 2013;77(6):1518-25.
71Yamazaki T, Nohara R, Daida H, Hata M, Kaku K, Kawamori R, Kishimoto J, Kurabayashi M, Masuda I, Sakuma I, Yokoi H, Yoshida M; Justification for Atherosclerosis Regression Treatment (JART) Investigators.
Intensive lipid-lowering therapy for slowing progression as well as inducing regression of atherosclerosis in Japanese patients: subanalysis of the JART study.
Int Heart J. 2013;54(1):33-9.
72Kawashiri MA, Yamagishi M, Sakamoto T, Takayama T, Hiro T, Daida H, Hirayama A, Saito S, Yamaguchi T, Matsuzaki M; COSMOS Investigators.
Impact of intensive lipid lowering on lipid profiles over time and tolerability in stable coronary artery disease: insights from a subanalysis of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS).
Cardiovasc Ther. 2013 Dec;31(6):335-43.
73Miura Y, Fukumoto Y, Miura T, Shimada K, Asakura M, Kadokami T, Ando S, Miyata S, Sakata Y, Daida H. Matsuzaki M, Yasuda S, Kitakaze M, Shimokawa H.
Impact of Physical Activity on Cardiovascular Events in Patients with Chronic Heart Failure -A Multi-center Prospective Cohort Study-.
Circ J. 77: 2963-2972;2013.
74Dohi T, Miyauchi K, Ohkawa R, Nakamura K, Kurano M, Kishimoto T, Yanagisawa N, Ogita M, Miyazaki T, Nishino A, Yaginuma K, Tamura H, Kojima T, Yokoyama K, Kurata T, Shimada K, Daida H, Yatomi Y.
Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome.
Atherosclerosis. 229:192-7;2013.
75Sai E, Shimada K, Yokoyama T, Sato S, Miyazaki T, Hiki M, Tamura Y, Aoki S, Watada H, Kawamori R, Daida H.
Association between Myocardial Triglyceride Content and Cardiac Function in Healthy Subjects and Endurance Athletes.
PLOS ONE. 8:e61604;2013.
76Nishitani M, Shimada K, Sunayama S, Masaki Y, Kume A, Fukao K, Sai E, Yamashita H, Ohmura H, Onishi T, Shioya M, Sato H, Shimada A, Yamamoto T, Amano A, Daida H.
Effect of cardiac rehabilitation on muscle mass, muscle strength, and exercise tolerance in diabetic patients after coronary artery bypass grafting.
J Cardiol. 61:216-221;2013.
77Matsumori R, Miyazaki T, Shimada K, Kume A, Kitamura Y, Oshida K, Yanagisawa N, Kiyanagi T, Hiki M, Fukao K, Hirose K, Ohsaka H, Mokuno H, Daida H.
High levels of very long-chain saturated fatty acid in erythrocytes correlates with atherogenic lipoprotein profiles in subjects with metabolic syndrome.
Diabetes Res Clin Pract. 99:12-18;2013.
78Ogita M, Miyauchi K, Dohi T, Tsuboi S, Miyazaki T, Yokoyama T, Yokoyama K, Shimada K, Kurata T, Jiang M, Bujo H, Daida H.
Increased circulating soluble LR11 in patients with acute coronary syndrome.
Clin Chim Acta. 415:191-194;2013.
79Sumi S, Origasa H, Houkin K, Terayama Y, Uchiyama S, Daida H, Shigematsu H, Goto S, Tanaka K, Miyamoto S, Minematsu K, Matsumoto M, Okada Y, Sato M, Suzuki N.
A modified Essen stroke risk score for predicting recurrent cardiovascular events: development and validation.
Int J Stroke. 2013 in press
80Sugihara M, Odagiri F, Suzuki T, Murayama T, Nakazato Y, Unuma K, Yoshida K, Daida H, Sakurai T, Morimoto S, Kurebayashi N.
Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model.
PLoS One. 8:e55514;2013.
81Kawata T, Konishi H, Amano A, Daida H.
Wavering calcified amorphous tumour of the heart in a haemodialysis patient.
Interact Cardiovasc Thorac Surg. 16:219-20;2013.
82Tsuboi S, Miyauchi K, Kasai T, Ogita M, Dohi T, Miyazaki T, Yokoyama T, Kojima T, Yokoyama K, Kurata T, Daida H.
Impact of red blood cell distribution width on long-term mortality in diabetic patients after percutaneous coronary intervention.
Circ J. 77:456-61;2013.
83Kasai T, Miyauchi K, Yanagisawa N, Kajimoto K, Kubota N, Ogita M, Tsuboi S, Amano A, Daida H.
Mortality risk of triglyceride levels in patients with coronary artery disease.
Heart. 99:22-9;2013.
84Fukushima Y, Daida H, Morimoto T, Kasai T, Miyauchi K, Yamagishi S, Takeuchi M, Hiro T, Kimura T, Nakagawa Y, Yamagishi M, Ozaki Y, Matsuzaki M; JAPAN-ACS Investigators.
Relationship between Advanced Glycation End Products and Plaque Progression in Patients with Acute Coronary Syndrome: The JAPAN-ACS Sub-study.
Cardiovasc Diabetol. 12:5;2013.
85Ogita M, Miyauchi K, Morimoto T, Daida H, Kimura T, Hiro T, Nakagawa Y, Yamagishi M, Ozaki Y, Matsuzaki M.
Association between circulating matrix metalloproteinase levels and coronary plaque regression after acute coronary syndrome--subanalysis of the JAPAN-ACS study.
Atherosclerosis. 226:275-80;2013.
86Nonomura K, Yamaguchi Y, Hamachi M, Koike M, Uchiyama Y, Nakazato K, Mochizuki A, Sakaue-Sawano A, Miyawaki A, Yoshida H, Kuida K, Miura M (2013)
Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.
Dev Cell 27: 621-634
87Abe H, Uchida T, Hara A, Mizukami H, Komiya K, Koike M, Shigihara N, Toyofuku Y, Ogihara T, Uchiyama Y, Yagihashi S, Fujitani Y, Watada H. (2013)
Exendin-4 improves beta cell function in autophagy-deficient beta cells.
Endicrinology 154: 4512-4524
88Sakata K, Ohmuraya M, Araki K, Suzuki C, Ida S, Hashimoto D, Wang J, Uchiyama Y, Baba H, Yamamura K (2013)
Generation and analysis of serine protease inhibitor Kazal type 3-Cre driver mice.
Exp Animals.
89Okura H, Kobayashi T, Koike M, Ohsawa M, Zhang D, Arai H, Uchiyama Y, Hino O (2013)
Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway.
Int J Oncol 43: 447-456
90Adachi T, Takahara K, Taneo J, Uchiyama Y, Inaba K (2013)
Particle size of latex beads dictates IL-1β production mechanism.
PLos One 8(7):e68499
91Koike M, Tanida I, Nanao N, Tada N, Iwata J, Ueno T, Kominami E, Uchiyama Y (2013)
Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons.
PLos One 8:e63568 (*equally contributed)
92*Matsui, H., *Sato, F., Sato, S., Koike, M., Taruno, Y., Saiki, S., Funayama, M., Ito, H., Taniguchi, Y., Uemura, N., Toyoda, A., Sakaki, Y., Takeda, S., Uchiyama, Y., Hattori, N., Takahashi, R.
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.
FEBS letters 587(9):1316-25, 2013. (*These authors contributed equally to this work)
93Ohkouchi S, Shibata M, Sasaki M, Koike M, Safig P, Peters C, Nagata S, Uchiyama Y (2013)
Biogenesis and proteolytic processing of lysosomal DNase II.
PLos One, 8:e59148
94Furuta A, Wakabayashi K, Haratake J, Kikuchi H, Kabuta T, Mori F, Tokonami F, Katsumi Y, Tanioka F, Uchiyama Y, Nishino I, Wada K (2013)
Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease.
Acta Neuropathol, 125:459-461
95Koike M, Shibata M, Ezaki J, Peters C, Saftig P, Kominami E, Uchiyama Y (2013)
Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous systems.
Eur J Neurosci, 37:816-830

英文原著(2012年)

1Ogaki, K., Hirayama, T., Chijiiwa, K., Fukae, J., Furuya, T., Noda, K., Fujishima, K., Hattori, N., Takahashi, T., & Okuma, Y.
Anti-aquaporin-4 Antibody-positive Definite Neuromyelitis Optica in a Patient With Thymectomy for Myasthenia Gravis.
Neurologist, 2012, 18(2), 76-79.
2Shimada Y, Yoritaka A, Tanaka Y, Miyamoto N, Ueno Y, Hattori N, Takao U.
Cerebral infarction in a young man using high-dose anabolic steroids.
J Stroke Cerebrovasc Dis. 2012 Nov;21(8):906.e9-11.
3Takagi-Akiba M, Asanuma K, Tanida I, Tada N, Oliva Trejo JA, Nonaka K, Asanuma E, Kominami E, Ueno T, Tomino Y.
Doxorubicin-induced glomerulosclerosis with proteinuria in GFP-GABARAP transgenic mice.
Am J Physiol - Renal Physiol. 2012 Feb; 302(3): F380-389.
4Futakawa S, Nara K, Miyajima M, Kuno A, Ito H, Kaji H, Shirotani K, Honda T, Tohyama Y, Hoshi K, Hanzawa Y, Kitazume S, Imamaki R, Furukawa K, Tasaki K, Arai H, Yuasa T, Abe M, Arai H, Narimatsu H, Hashimoto Y:
A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH.
Neurobiol Aging. 33(8): 1807-1815, 2012
5Watanabe M, Miyajima M, Nakajima M, Arai H, Ogino I, Nakamura S, Kunichika5:
Expression analysis of high mobility group box-1 protein (HMGB-1) in the cerebral cortex, hippocampus, and cerebellum of the congenital hydrocephalus (H-Tx) rat.
Acta Neurochir Suppl. 113:91-96, 2012
6Nakajima M, Miyajima M, Ogino I, Watanabe M, Hagiwara Y, Segawa T, Kobayashi K, Arai H:
Brain localization of leucine-rich α2-glycoprotein and its role.
Acta Neurochir Suppl.113: 97-101, 2012
7Miyajima M, Shimoji K, Watanabe M, Nakajima M, Ogino I, Arai H:
Role of artificial cerebrospinal fluid as perfusate in neuroendoscopic surgery: a basic investigation.
Acta Neurochir Suppl.113:103-7, 2012
8Kakuda N, Shoji M, Arai H, Furukawa K, Ikeuchi T, Akazawa K, Takami M, Hatsuta H, Murayama S, Hashimoto Y, Miyajima M, Arai H, Nagashima Y, Yamaguchi H, Kuwano R, Nagaike K, Ihara Y;
Japanese Alzheimer's Disease Neuroimaging Initiative: Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
EMBO Mol Med. 4(4):344-352, 2012
9Shimizu A, Komuro Y, Miyajima M, Arai H:
Familial nonsyndromic craniosynostosis with specific deformity of the cranium.
J Neurosurg Pediatr. 10(6):560-564, 2012
10Mori E, Ishikawa M, Kato T, Kazui H, Miyake H, Miyajima M, Nakajima M, Hashimoto M, Kuriyama N, Tokuda T, Ishii K, Kaijima M, Hirata Y, Saito M, Arai H:
Guidelines for management of idiopathic normal pressure hydrocephalus: second edition.
Neurol Med Chir (Tokyo). 52(11):775-809, 2012
11Ueda A, Shimizu A, Natori Y, Sonoue H, Komuro Y, Miyajima M, Arai H:
Expression of transforming growth factor-β1, -β2, and -β3 in plagiocephalic fused and patent coronal suture.
J Craniofac Surg. 23(3):755-757, 2012
12Ohnuma T, Sakai Y, Maeshima H, Higa M, Hanzawa R, Kitazawa M, Hotta Y, Katsuta N,Takebayashi Y, Shibata N, Arai H.
No Correlation between Plasma NMDA-Related Glutamatergic Amino Acid Levels and Cognitive Function in Medicated Patients with Schizophrenia.
The International Journal of Psychiatry in Medicine.2012:44(1):17-27.
13Ohnuma T, Nakamura T, Takebayashi Y, Hanzawa R, Kitazawa M, Higashiyama R, Takeda M, Thompson K, Komatsu M, Shimazaki H, Shibata N, Arai H.
No Associations Found between PGBD1 and the Age of Onset in Japanese Patients Diagnosed with Sporadic Alzheimer's Disease.
Dement Geriatr Cogn Dis Extra. 2012:Jan;2(1):496-502.
14Shibata N, Motoi Y, Tomiyama H, Ohnuma T, Kuerban B, Tomson K, Komatsu M, Hattori N, Arai H. 
Lack of Genetic Association of the UCHL1 Gene with Alzheimer's Disease and Parkinson's Disease with Dementia.
Dement Geriatr Cogn Disord. 2012:Jun 8;33(4):250-254.
15Takagi-Akiba M, Asanuma K, Tanida I, Tada N, Oliva Trejo JA, Nonaka K, Asanuma E, Kominami E, Ueno T, Tomino Y.
Doxorubicin-induced glomerulosclerosis with proteinuria in GFP-GABARAP transgenic mice.
Am J Physiol - Renal Physiol. 2012 Feb; 302(3): F380-389.
16Uka T, Sasaki R, Kumano H.
Change in Choice-Related Response Modulation in Area MT during Learning of a Depth-Discrimination Task is Consistent with Task Learning.
J Neurosci. 32: 13689-13700, 2012.
17Kumano H, Uka T.
Reduction in receptive field size of macaque MT neurons in the presence of visual noise.
J Neurophysiol. 108: 215-226, 2012.
18Hosozawa M, Tanaka K, Shimizu T, Nakano T, Kitazawa S.
How children with specific language impairment view social situations.
Pediatrics. 129: 1453-1460, 2012.
19Uchida Y, Kudoh D, Murakami A, Honda M, Kitazawa S.
Origins of superior dynamic visual acuity in baseball players: superior eye movements or superior image processing.
PlosOne. 7: e31530, 2012.
20Nakano T, Kato N, Kitazawa S.
Superior haptic-to-visual shape matching in autism spectrum disorders.
Neuropsychologia. 50: 696-703, 2012
21Ichikawa-Tomikawa N, Ogawa J, Douet V, Xu Z, Kamikubo Y, Sakurai T, Kohsaka S, Chiba H, Hattori N, Yamada Y, & Arikawa-Hirasawa E.
Laminin alpha1 is essential for mouse cerebellar development.
Matrix Biol. 2012 Jan;31(1):17-28.
22Inoue Y, Uchimura N, Kuroda K, Hirata K, Hattori N.
Long-term efficacy and safety of gabapentin enacarbil in Japanese restless legs syndrome patients.
Prog Neuropsychopharmacol Biol Psychiatry, 2012, 36(2), 251-257.
23Ogaki K, Li Y, Takanashi M, Ishikawa K, Kobayashi T, Nonaka T, Hasegawa M, Kishi M, Yoshino H, Funayama M, Tsukamoto T, Shioya K, Yokochi M, Imai H, Sasaki R, Kokubo Y, Kuzuhara S, Tomiyama H, Hattori N.
Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP,and CBS.
Parkinsonism Relat Disord. 2012;19(1):15-20.
24Kanao T, Sawada T, Davies SA, Ichinose H, Hasegawa K, Takahashi R, Hattori N, Imai Y.
The Nitric Oxide-Cyclic GMP Pathway Regulates FoxO And Alters Dopaminergic Neuron Survival in Drosophila.
PLoS One. 2012;7(2):e30958.
25Shiba-Fukushima K, Imai Y, Yoshida S, Ishihama Y, Kanao T, Sato S, Hattori N.
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy.
Sci Rep. 2012;2:1002.
26Shibata N, Motoi Y, Tomiyama H, Ohnuma T, Kuerban B, Tomson K, Komatsy M, HattoriN, Arai H.
Lack of Genetic association of the UCHL1Gene with Alzheimer's disease and Parkinson's disease with dementia.
Demen Geriatr Cogn Disord 2012;33;250-254
27Tanaka R, Kawanabe T, Yamauchi Y, Shimura H, Tanaka Y, Miyamoto N, Ueno Y, Urabe T, Hattori N, Tanaka S.
Economy class stroke syndrome after a long drive.
J Stroke Cerebrovasc Dis. 2012 Feb;21(2):155-7.
28Hasegawa T, Ichiba M, Matsumoto SE, Kasanuki K, Hatano T, Fujishiro H, Iseki E, Hattori N, Yamada T, Tabira T.
Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients.
Journal of Alzheimer's disease 2012 Mar; 31(1):59–64.
29Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton WM, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B.
Parkinson’s disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.
PLoS Genet. 2012;8(3):e1002537.
30Ogaki K, Hirayama T, Chijiiwa K, Fukae J, Furuya T, Noda K, Fujishima K, Hattori N, Takahashi T, Okuma Y.
Anti-aquaporin-4 antibody-positive definite neuromyelitis optica in a patient with thymectomy for myasthenia gravis.
Neurologist. 2012 Mar;18(2):76-9.
31Funayama M, Yoshino H, Li Y, Kusaka H, Tomiyama H, Hattori N.
Pseudo-heterozygous rearrangement mutation of parkin.
parkin. Mov Disord. 2012 Apr;27(4):552-5.
32Shimada K, Motoi Y, Ishiguro K, Kambe T, Matsumoto SE, Itaya M, Kunichika M, Mori H, Shinohara A, Chiba M, Mizuno Y, Ueno T, Hattori N.
Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: implications of autophagy promotion.
Neurobiol Dis. 2012 Apr;46(1):101-8.
33Tomizawa Y, Yokoyama K, Saiki S, Takahashi T, Matsuoka J, Hattori N.
Blood-Brain Barrier Disruption is More Severe in Neuromyelitis Optica than in Multiple Sclerosis and Correlates with Clinical Disability.
J Int Med Res. 2012;40(4):1483-91.
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40Ujiie S, Hatano T, Kubo S, Imai S, Sato S, Uchihara T, Yagishita S, Hasegawa K, Kowa H, Sakai F, Hattori N.
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43Fusegi K, Hattori N, Mizuno Y, Mori H.
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44Hattori N, Hasegawa K, Sakamoto T.
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45Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, Shouji M, Nakanishi A, Suzuki N, Mizuno Y, Mizushima N, Amagai M, Uchiyama Y, Mochizuki H, Hattori N, Okano H.
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46Ogaki K, Li Y, Atsuta N, Tomiyama H, Funayama M, Watanabe H, Nakamura R, Yoshino H, Yato S, Tamura A, Naito Y, Taniguchi A, Fujita K, Izumi Y, Kaji R, Hattori N, Sobue G; Japanese Consortium for Amyotrophic Lateral Sclerosis research (JaCALS).
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48Shimada Y, Yoritaka A, Tanaka Y, Miyamoto N, Ueno Y, Hattori N, Takao U.
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49Yamashiro K, Mori A, Shimada Y, Furuya T, Noda K, Urabe T, Hattori N, Okuma Y.
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50Yamashiro K, Tanaka R, Nishioka K, Ueno Y, Shimura H, Okuma Y, Hattori N, Urabe T:
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51Ando K, Doi T, Moody S.Y, Ohkuni Y, Sato A, Kaneko N.
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52Ando K, Tobino K, Kurihara M, Kataoka H, Doi T, Hoshika Y, Takahashi K, Seyama K.
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53Chiba N, Comaills V, Shiotani B, Takahashi F, Shimada T, Tajima K, Winokur D, Hayashida T, Willers H, Brachtel E, Vivanco MD, Haber DA, Zou L, Maheswaran S.
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54Fujii M, Iwakami SI, Takagi H, Itoigawa Y, Ichikawa M, Iwakami N, Ishiwata T, Seyama K, Takahashi K.
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55Hayashi T, Koike K, Kumasaka T, Saito T, Mitani K, Terao Y, Ogishima D, Yao T, Takeda S, Takahashi K, Seyama K.
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56Ishiwata T, Harada N, Ko R, Hara M, Sekiya M, Sasaki S, Nobukawa B, Takahashi K.
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57Kanaji N, Nelson A, Allen-Gipson DS, Sato T, Nakanishi M, Wang X, Li Y, Basma H, Michalski J, Farid M, Rennard SI, Liu X.
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58Koyama R, Miura K, Yae S, Murakami A, Takahashi K.
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59Kaira K, Abe M, Nakagawa K, Ohde Y, Okumura T, Takahashi T, Murakami H, Shukuya T, Kenmotsu H, Naito T, Hayashi I, Oriuchi N, Endo M, Kondo H, Nakajima T, Yamamoto N.
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60Makino F, Ito J, Abe Y, Harada N, Kamachi F, Y Hideo, Takahashi K, Okumura K, Akiba H.
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61Minakata K, Takahashi F, Nara T, Hashimoto M, Tajima K, Murakami A, Nurwidya F, Yae S, Koizumi F, Moriyama H, Seyama K, Nishio K, Takahashi K.
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62Murakami A, Ohashi R, Minakata K, Koyama R, Muraki K, Shukuya T, Namba Y, Ko R, Yagishita S, Katsura Y, Takahashi F, Sakuraba S, Takahashi K.
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63Muraki K, Koyama R, Honma Y, Yagishita S, Shukuya T, Ohashi R, Takahashi F, Kido K, Iwakami S, Sasaki S, Iwasse A, Takahashi K.
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64Nagashima O, Iwase A, Yae T, Kadoya K, Ishimori A, Kuriyama S, Koyama R, Homma N, Ienaga H, Takahashi K.
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65Nakanishi M, Sato T, Li Y, Nelson A, Farid M, Michalski J, Kanaji N, Wang X, Basma H, Patil A, Goraya J, Liu X, Togo S, Toews ML, Holz O, Muller K, Magnussen H, Rennard SI.
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66Ohwada A, Takahashi K.
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67Okuzumi A, Kimura T, Katsura Y, Miyaji A, Hirama M, Kido K, Ogura K, Hishii M, Takahashi K.
Pulmonary Metastases from carotid body paraganglioma: a case report.
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68Shukuya T, Takahashi T, Harada H, Akamatsu H, Sakaguchi C, Imai H, Ono A, Nakamura Y, Tsuya A, Kenmotsu H, Naito T, Murakami H, Endo M, Takahashi K, Yamamoto N.
Comparison of vinorelbine plus cisplatin and s-1 plus cisplatin in concurrent chemoradiotherapeutic regimens for unresectable stage III non-small cell lung cancer.
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69Tobino K, Hirai T, Johkoh T, Kurihara M, Fujimoto K, Tomiyama N, Mishima M, Takahashi K, Seyama K.
Differentiation between Birt-Hogg Dubé syndrome and lymphangioleiomyomatosis: Quantitative analysis of pulmonary cysts on computed tomography of the chest in 66 females.
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70Yae T, Tsuchihashi K, Ishimoto T, Motohara T, Yoshioka M, Yoshida J. G, Wada T, Masuko T, Mogushi K, Tanaka H, Osawa T, Kanki Y, Minami T, Aburatani H, Ohmura M, Kubo A, Suematsu M, Takahashi K, Saya H, Nagano O.
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.
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71Yae S, Takahashi F, Yae T, Yamaguchi T, Tsukada R, Koike K, Minakata M, Murakami A,Nurwidya F, Kato M, Tamada M, Yoshikawa M, Kobayashi H, Seyama K, Takahashi K.
Hochuekkito(TJ-41), a Kampo Formula, Ameliorates Cachexia Induced by Colon 26 Adenocarcinoma in Mice.
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72Yoshimi K, Ueki J, Seyama K, Takizawa M, Yamaguchi S, Kitahara E, Fukazawa S, Takahama Y, Ichikawa M, Takahashi, Fukuchi Y.
Pulmonary rehabilitation program including respiratory conditioning for chronic obstructive pulmonary disease (COPD): Improved hyperinflation and expiratory flow during tidal breathing.
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73Ichikawa-Tomikawa N, Ogawa J, Douet V, Xu Z, Kamikubo Y, Sakurai,T, Kohsaka S, Chiba H, Hattori H, Yamada Y, and Arikawa-Hirasawa E. 
Laminin a1 is essential for mouse cerebellar development 
Matrix Biol. 31, Pages 17–28 2012 IF:5.074
74Mercier F, Arikawa-Hirasawa E:
Heparan sulfate niche for cell proliferation in the adult brain.
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75Yoshinaga H, Sakoda,S Good JM, Takahashi MP, Kubota T, Arikawa-Hirasawa E, Nakata T, Ohno K, Kitamura T, Kobayashi K, and Ohtsuka Y:
A novel mutation in SCN4A causes severe myotonia and school-age-onset paralytic episodes.
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76Inomata T , Ebihara N, Funaki, T Matsuda A, Watanabe Y, Ning L, Xu Z, Murakami A, Arikawa-Hirasawa E:
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77Ishijima M, Suzuki N, Hozumi K, Matsunobu T, Kosaki K, Kaneko H, Hassell JR, Arikawa-Hirasawa E, Yamada Y
Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation.
Matrix Biol. 31:234-45 2012. IF: 5.074
78Suzuki N, Fukushi M, Kosaki K, Doyle AD, de Vega S, Yoshizaki K, Akazawa C, Arikawa-Hirasawa E, Yamada Y
Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS..
J Neurosci. 32:11586-99. 2012 IF:6.344
79Futami I, Ishijima M, Kaneko H, Tsuji K, Ichikawa-Tomikawa N, Sadatsuki R, Muneta T, Arikawa-Hirasawa E, Sekiya I, Kaneko K
Isolation and Characterization of MultipotentialMesenchymal Cells from the Mouse Synovium.
PLoS ONE 7: e45517 1-12 2012 IF:3.534
80Douet V, Arikawa-Hirasawa E, Mercier F.
Fractone-heparan sulfates mediate BMP-7 inhibition of cell proliferation in the adult subventricular zone.
Neurosci Lett. Neurosci Lett. 52:120-5. 2012. IF:2.030
81Ogita M, Miyauchi K, Dohi T, Tsuboi S, Miyazaki T, Yokoyama T, Yokoyama K, Shimada K, Kurata T, Jiang M, Bujo H, Daida H.
Increased circulating soluble LR11 in patients with acute coronary syndrome.
Clin Chim Acta. 415:191-194;2013.
82Nishizaki Y, Yamashita H, Yamagami S, Daida H.
Large bilateral isolated internal iliac artery aneurysms.
Intern Med. 51:3099-100;2012.
83Dohi T, Kasai T, Miyauchi K, Takasu K, Kajimoto K, Kubota N, Amano A, Daida H.
Prognostic impact of chronic kidney disease on 10-year clinical outcomes among patients with acute coronary syndrome.
J Cardiol. 60:438-42;2012.
84Tamura Y, Ono T, Kuwana M, Inoue K, Takei M, Yamamoto T, Kawakami T, Fujita J, Kataoka M, Kimura K, Sano M, Daida H, Satoh T, Fukuda K.
Human pentraxin 3 (PTX3) as a novel biomarker for the diagnosis of pulmonary arterial hypertension.
PLoS One. 7:e45834;2012.
85Kitagawa Y, Teramoto T, Daida H; APPROACH-J Study group.
Adherence to preferable behavior for lipid control by high-risk dyslipidemic Japanese patients under pravastatin treatment: the APPROACH-J study.
J Atheroscler Thromb. 19:795-805;2012.
86Nishizaki Y, Yamagami S, Suzuki H, Joki Y, Takahashi S, Sesoko M, Yamashita H, Kuremoto K, Shinozaki T, Daida H.
Red blood cell distribution width as an effective tool for detecting fatal heart failure in super-elderly patients.
Intern Med. 51:2271-6;2012.
87Takashima H, Ozaki Y, Morimoto T, Kimura T, Hiro T, Miyauchi K, Nakagawa Y, Yamagishi M, Daida H, Mizuno T, Asai K, Kuroda Y, Kosaka T, Kuhara Y, Kurita A, Maeda K, Amano T, Matsuzaki M; JAPAN-ACS Investigators.
Clustering of metabolic syndrome components attenuates coronary plaque regression during intensive statin therapy in patients with acute coronary syndrome: the JAPAN-ACS subanalysis study.
Circ J. 76:2840-7;2012.
88Dohi T, Miyauchi K, Ohkawa R, Nakamura K, Thuboi S, Ogita M, Miyazaki T, Nishino A, Yokoyama K, Kurata T, Yatomi Y, Daida H.
Higher lipoprotein-associated phospholipase A2 levels are associated with coronary atherosclerosis documented by coronary angiography.
Ann Clin Biochem. 49:527-33;2012.
89Daida H, Takayama T, Hiro T, Yamagishi M, Hirayama A, Saito S, Yamaguchi T, Matsuzaki M; COSMOS Investigators.
High HbA1c levels correlate with reduced plaque regression during statin treatment in patients with stable coronary artery disease: results of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS).
Cardiovasc Diabetol. 11:87;2012.
90Ohkawa R, Kishimoto T, Kurano M, Dohi T, Miyauchi K, Daida H, Nagasaki M, Uno K, Hayashi N, Sakai N, Matsuyama N, Nojiri T, Nakamura K, Okubo S, Yokota H, Ikeda H, Yatomi Y.
Development of an enzymatic assay for sphingomyelin with rapid and automatable performances: Analysis in healthy subjects and coronary heart disease patients.
Clin Biochem. 45:1463-70;2012.
91Miyauchi K, Yamazaki T, Watada H, Tanaka Y, Kawamori R, Imai Y, Ikeda S, Kitagawa A, Ono Y, Murayama F, Choi JB, Suwa S, Hayashi D, Kishimoto J, Daida H; ADVANCED-J investigators.
Management of home blood pressure by amlodipine combined with angiotensin II receptor blocker in type 2 diabetes.
Circ J. 76:2159-66;2012.
92Yamada A, Takeuchi Y, Nishizaki Y, Daida H.
Bag-valve-mask ventilation with airway adjuncts improves neurological outcomes of in-hospital cardiac arrest.
Intern Med. 2012;51(12):1517-21.
93Hashimoto R, Katoh Y, Nakamura K, Itoh S, Iesaki T, Daida H, Nakazato Y, Okada T.
Enhanced accumulation of adipocytes in bone marrow stromal cells in the presence of increased extracellular and intracellular [Ca²⁺].
Biochem Biophys Res Commun. 423:672-8;2012.
94Yamase M, Nakazato Y, Daida H.
Effectiveness of amiodarone versus bepridil in achieving conversion to sinus rhythm in patients with persistent atrial fibrillation: a randomised trial.
Heart. 98:1067-71;2012.
95Suzuki T, Shioya T, Murayama T, Sugihara M, Odagiri F, Nakazato Y, Nishizawa H, Chugun A, Sakurai T, Daida H,
Morimoto S, Kurebayashi N. Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.
PLoS One. 7:e35353;2012.
96Nishizaki Y, Yamagami S, Haga K, Sesoko M, Yamashita H, Miyauchi K, Daida H.
Usefulness of prominently projected aortic arch on chest radiograph to predict severe tortuosity of the right subclavian or brachiocephalic artery in patients aged >44 years undergoing coronary angiography with a right radial artery approach.
Am J Cardiol. 110:203-7;2012.
97Hirano K, Yamashita T, Suzuki S, Hayama E, Matsuoka J, Otsuka T, Sagara K, Fu LT, Sawada H, Aizawa T, Nakazato Y, Daida H.
Relationship between 24-h Holter recordings and clinical outcomes in patients with permanent atrial fibrillation.
J Cardiol. 60:42-6;2012.
98Kajimoto K, Miyauchi K, Yamamoto T, Daida H, Amano A. 
Meta-analysis of randomized controlled trials on the treatment of unprotected left main coronary artery disease: one-year outcomes with coronary artery bypass grafting versus percutaneous coronary artery intervention with drug-eluting stent.
J Card Surg. 27:152-7;2012.
99Okai I, Inoue K, Maruyama M, Maruyama S, Komatsu K, Nishizawa H, Okazaki S, Fujiwara Y, Sumiyoshi M, Daida H. 
Transbrachial intra-aortic balloon pumping for a patient with fulminant myocarditis. 
Heart Vessels. 27:639-42;2012.
100Dohi S, Kajimoto K, Miyauchi K, Yamamoto T, Tambara K, Inaba H, Kuwaki K, Tamura H, Kojima T, Yokoyama K, Kurata T, Daida H, Amano A.
Comparing outcomes after off-pump coronary artery bypass versus drug-eluting stent in diabetic patients.
J Cardiol. 59:195-201;2012.
101Sekita G, Fukushima K, Takeuchi H, Daida H.
Coronary artery fistula with giant aneurysm.
J Card Surg. 27:602-3;2012.
102Matsumori R, Shimada K, Kiyanagi T, Hiki M, Fukao K, Hirose K, Ohsaka H, Miyazaki T, Kume A, Yamada A, Takagi A, Ohmura H, Miyauchi K, Daida H.
Clinical significance of the measurements of urinary liver-type fatty acid binding protein levels in patients with acute coronary syndrome.
J Cardiol. 60:168-173;2012.
103Takahashi Y, Shimada K, Sumiyoshi K, Kiyanagi T, Hiki M, Fukao K, Hirose K, Matsumori R, Ohsaka H, Kume A, Miyazaki T, Miyajima H, Nagaoka I, Daida H.
Clinical Significance of Monocyte-derived Dendritic Cell Activation in Patients with Acute Coronary Syndrome.
World J Cardiovasc Dis. 2012 2:74-81;2012
104Suzuki N, Sato M, Houkin K, Terayama Y, Uchiyama S, Daida H, Shigematsu H, Goto S, Tanaka K, Origasa H, Miyamoto S, Minematsu K, Matsumoto M, Okada Y.
One-year Atherothrombotic Vascular Events Rates in Outpatients with Recent Non-cardioembolic Ischemic Stroke: The EVEREST (Effective Vascular Event REduction after STroke) Registry.
J Stroke Cerebrovasc Dis. 21:245-53;2012.
105Miyauchi K, Daida H, Morimoto T, Hiro T, Kimura T, Nakagawa Y, Yamagishi M, Ozaki Y, Kadota K, Kimura K, Hirayama A, Kimura K, Hasegawa Y, Uchiyama S, Matsuzaki M; for the JAPAN-ACS Investigators.
Reverse Vessel Remodeling But Not Coronary Plaque Regression Could Predict Future Cardiovascular Events in ACS Patients With Intensive Statin Therapy.
Circ J. 76:825-832;2012.
106Teramoto T, Shirai K, Daida H, Yamada N.
Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study.
Cardiovasc Diabetol. 11:29;2012.
107Fukushima Y, Ohmura H, Mokuno H, Kajimoto K, Kasai T, Hirayama S, Miyauchi K, Miida T, Amano A, Daida H.
Non-high-density lipoprotein cholesterol is a practical predictor of long-term cardiac death after coronary artery bypass grafting.
Atherosclerosis. 221:206-11;2012.
108Ohsaka h, Shimada K, Fukao K, Sai E, Fukushima Y, Masuda H, Hirose K, Yoshihara T, Matsumori R, Hiki M, Kiyanagi T, Kume A, Yamashita H, Miyazaki T, Daida H.
Clinical and prognostic features in asymptomatic and symptomatic patients with arteriosclerosis obliterans.
World J Cardiovasc Dis. 2:1-7;2012
109Fukao K, Shimada K, Naito H, Sumiyoshi K, Inoue N, Iesaki T, Yasue T, Toyoda S, Yoshihara T, Kume A, Kiyanagi T, Hiki M, Hirose K, Matsumori R, Ohsaka H, Sai E, Yamashita H, Miyazaki T, Itoh S, Tada N, Daida H.
Effects of Voluntary Exercise on the Progression of Atherosclerotic Lesions in Apolipoprotein E-Deficient Mice: Protective Role against Vascular Inflammation.
Inangural International Academy of Sportology Proceeding. 105-110;2012
110Dohi T, Miyauchi K, Ohkawa R, Nakamura K, Kishimoto T, Miyazaki T, Nishino A, Nakajima N, Yaginuma K, Tamura H, Kojima T, Yokoyama K, Kurata T, Shimada K, Yatomi Y, Daida H.
Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome.
Clin Chim Acta. 413:207-212;2012
111Nohara R, Daida H, Hata M, Kaku K, Kawamori R, Kishimoto J, Kurabayashi M, Masuda I, Sakuma I, Yamazaki T, Yokoi H, Yoshida M; Justification for Atherosclerosis Regression Treatment (JART) Investigators.
Effect of intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness in Japanese patients: Justification for Atherosclerosis Regression Treatment (JART) study.
Circ J. 76:221-9;2012.
112Maruyama S, Shibata R, Kikuchi R, Izumiya Y, Rokutanda T, Araki S, Kataoka Y, Ohashi K, Daida H, Kihara S, Ogawa H, Murohara T, Ouchi N.
Fat-derived factor omentin stimulates endothelial cell function and ischemia-induced revascularization via endothelial nitric oxide synthase-dependent mechanism.
J Biol Chem. 287:408-17;2012.
113Kasai T, Miyauchi K, Kubota N, Kajimoto K, Amano A, Daida H.
Probucol therapy improves long-term (>10-year) survival after complete revascularization: a propensity analysis.
Atherosclerosis. 220:463-9;2012.
114Piao X, Komazawa-Sakon S, Nishida T, Koike M, Piao JH, Ehlken H, Kurihara H, Hara M, van Rooijen N, Schütz G, Ohmuraya M, Uchiyama Y, Yagita H, Okumura K, He YW, Nakano H (2012)
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Sci Signal doi:10.1126/scsignal. 2003448
115Tashiro Y, Urushitani M, Inoue H, Koike M, Uchiyama Y, Komatsu M, Tanaka K, Yamazaki M, Abe M, Misawa H, Sakimura K, Ito H, Takahashi R (2012)
Motor Neuron-specific Disruption of Proteasomes, but not Autophagy, Replicates Amyotrophic Lateral Sclerosis.
J Biol Chem, 287:42984-42994
116Unno T, Wakamori M, Koike M, Uchiyama Y, Ishikawa K, Kubota H, Yoshida T, Sasakawa H, Peters C, Mizusawa H, Watase K (1912)
Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6.
Proc Natl Acad Sci USA, 109: 17693-17698,2012
117Hayakawa N, Shiozaki M, Shibata M, Koike M, Uchiyama Y, Matsuura M, Gotow T (2012)
Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions.
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118Sekine S, Kanamaru Y, Koike M, Nishihara A, Okada M, Kinoshita H, Kamiyama J, Maruyama J, Uchiyama Y, Ishihara N, Takeda K, Ichijo H (2012)
Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.
J Biol Chem, 287: 34635-34645, PMID: 22915595
119Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, Shouji M, Nakanishi A, Suzuki N, Mizushima N, Amagai M, Uchiyama Y, Mochizuki H, Hattori N, Okano H (2012)
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
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英文原著(2011年)

1Kambe T, Inoue R, Kojima N, Tada N, Kimura T, Sahara N, Yamashita S, Mizoroki T, Takashima A, Shimada K, Ishiguro K, Mizuma H, Onoe H, Mizuno Y, Hattori N, Motoi Y.
Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice.
Neurobiol Dis. 2011 Jun; 42(3): 404-414.
2Ezaki J, Matsumoto N, Takeda-Ezaki M, Komatsu M, Takahashi K, Hiraoka Y, Taka H, Fujimura T, Takehana K, Yoshida M, Iwata J, Tanida I, Furuya N, Zheng D-M, Tada N, Tanaka K, Kominami E, Ueno T.
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.
Autophagy. 2011 Jul; 7: 727-736.
3Watanabe T, Kanamaru Y, Liu C, Suzuki Y, Tada N, Okumura K, Horikoshi S, Tomino Y.
Negative regulation of inflammatory responses by IgA receptor (FcαRI) inhibits the development of TLR9 signaling-accelerated glomerulonephritis.
Clin Exp Immunol. 2011 Nov; 166(2): 235-250.
4Komuro Y, Shimizu A, Ueda A, Miyajima M, Nakanishi H, Arai H:
Whole cranial vault expansion by continual occipital and fronto-orbital distraction in syndromic craniosynostosis.
J Craniofac Surg. 22(1):269-272, 2011
5Nakajima M, Miyajima M, Ogino I, Watanabe M, Miyata H, Karagiozov KL, Arai H, Hagiwara Y, Segawa T, Kobayashi K, Hashimoto Y:
Leucine-rich α-2-glycoprotein is a marker for idiopathic normal pressure hydrocephalus.
Acta Neurochir (Wien). 153(6):1339-46; discussion 1346, 2011
6Shirotani K, Futakawa S, Nara K, Hoshi K, Saito T, Tohyama Y, Kitazume S, Yuasa T, Miyajima M, Arai H, Kuno A, Narimatsu H, Hashimoto Y:
High Throughput ELISAs to Measure a Unique Glycan on Transferrin in Cerebrospinal Fluid: A Possible Extension toward Alzheimer's Disease Biomarker Development.
Int J Alzheimers Dis.;2011:352787, 2011
7Okura H, Yatomi K, Saito Y, Kasuga C, Ishii H, Karagiozov K, Miyajima M, Arai H:
Unexpected intraparenchymal hematoma caused by brain metastasis in a patient with neuroblastoma: case report.

Neurol Med Chir (Tokyo). 51(11):784-888, 2011
8Hayashi N, Murai H, Ishihara S, Kitamura T, Miki T, Miwa T, Miyajima M, Nishiyama K, Ohira T, Ono S, Suzuki T, Takano S, Date I, Saeki N, Endo S:
Nationwide investigation of the current status of therapeutic neuroendoscopy for ventricular and paraventricular tumors in Japan.
J Neurosurg 115(6):1147-57,2011
9Shibata N, Arai H. 
New diagnostic criteria for Alzheimer's disease from Alzheimer's association.
Japanese. Nihon Rinsho. 2011:Dec;69 Suppl 10(Pt 2):270-3.
10Shibata N, Ohnuma T, Kuerban B, Komatsu M, Arai H. 
Genetic association between ghrelin polymorphisms and Alzheimer's disease in a Japanese population. 
Dement Geriatr Cogn Disord.2011:32(3):178-81.
11Shibata N, Ohnuma T, Kuerban B, Komatsu M, Baba H, Arai H.
Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population. 
Int J Alzheimers Dis.2011:762471.
12Komatsu M, Shibata N, Kuerban B, Ohnuma T, Baba H, Arai H.
Genetic association between clusterin polymorphisms and Alzheimer's disease in a Japanese population.
Psychogeriatrics.2011:Mar;11(1):14-8.
13Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, Riemenschneider M, Owen M, Harold D, Hollingworth P, Cellini E, Sorbi S, Nacmias B, Takeda M, Pericak-Vance MA, Haines JL, Younkin S, Williams J, van Broeckhoven C, Farrer LA, St George-Hyslop PH, Mayeux R.
Meta-analysis of the association between variants in SORL1 and Alzheimer disease. 
Arch Neurol. 2011:Jan;68(1):99-106.
14Kambe T, Inoue R, Kojima N, Tada N, Kimura T, Sahara N, Yamashita S, Mizoroki T, Takashima A, Shimada K, Ishiguro K, Mizuma H, Onoe H, Mizuno Y, Hattori N, Motoi Y.
Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice.
Neurobiol Dis. 2011 Jun; 42(3): 404-414.
15Ezaki J, Matsumoto N, Takeda-Ezaki M, Komatsu M, Takahashi K, Hiraoka Y, Taka H, Fujimura T, Takehana K, Yoshida M, Iwata J, Tanida I, Furuya N, Zheng D-M, Tada N, Tanaka K, Kominami E, Ueno T.
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.
Autophagy. 2011 Jul; 7: 727-736.
16Watanabe T, Kanamaru Y, Liu C, Suzuki Y, Tada N, Okumura K, Horikoshi S, Tomino Y.
Negative regulation of inflammatory responses by IgA receptor (FcαRI) inhibits the development of TLR9 signaling-accelerated glomerulonephritis.
Clin Exp Immunol. 2011 Nov; 166(2): 235-250.
17Abe K, Takahashi T, Takikawa Y, Arai H, Kitazawa S.
Applying independent component analysis to detect silent speech in MRI signals.
Eur J Neurosci. 34: 1189-1199, 2011.
18Sasaki, R., Uka, T.
Psychophysical evidence for contraction of the range of spatial integration as a mechanism for filtering out spatial noise in a random dot motion display.
Vision Res. 51: 1979-1985, 2011.
19Nakano T.,Kato, N., Kitazawa S.
Lack of eyeblink entrainments in autism spectrum disorders.
Neuropsychologia 49: 2784-90, 2011.
20Yoshimi K, Naya Y, Mitani N, Kato T, Inoue M, Natori S, Takahashi T, Weitemier A, Nishikawa N, McHugh T, Einaga Y, and Kitazawa S.
Phasic reward responses in the monkey striatum as detected by voltammetry with diamond microelectrodes.
Neurosci Res 71: 49-62, 2011.
21Takahashi T, Takikawa Y, Kawagoe R, Shibuya S, Iwano T, Kitazawa S.
Influence of skin blood flow on near-infrared spectroscopy signals measured on the forehead during a verbal fluency task.
NeuroImage 57: 991-1002, 2011.
22Amo T, Sato S, Saiki S, Wolf AM, Toyomizu M, Gautier CA, Shen J, Ohta S, Hattori N.
Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.
Neurobiol Dis. 2011;41(1):111-8.
23Oizumi H, Tanaka R, Shimura H, Sasaki K, Koike H, Hattori N, Tanaka S.
A case of cerebral embolism with metastatic chondrosarcoma in the left atrium.
J Stroke Cerebrovasc Dis. 2011;20(1):79-81.
24Takamatsu, Y., Shiotsuki, H., Kasai, S., Sato, S., Iwamura, T., Hattori, N., & Ikeda, K.
Enhanced Hyperthermia Induced by MDMA in Parkin Knockout Mice.
Current Neuropharmacology, 9(1), 96-99. (2011).
25Yoritaka A, Shimo Y, Shimo Y, Inoue Y, Yoshino H, Hattori N.
Nonmotor Symptoms in Patients with PARK2 Mutations.
Parkinsons Dis. 2011 Jan 13;2011:473640.
26Hayashi C, Funayama M, Li Y, Kawano A, Suzuki M, Hattori N, Ikeda K. Hayashi C, Funayama M, Li Y, Kamiya K, Kawano A, Suzuki M, Hattori N, Ikeda K.
Prevalence of GJB2 causing recessive profound non-syndromic deafness in Japanese children.
Int J Pediatr Otorhinolaryngol. 2011 Feb;75(2):211-4.
27Ogaki K, Motoi Y, Li Y, Tomiyama H, Shimizu N, Takanashi M, Nakanishi A, Yokoyama K, Hattori N.
Visual Grasping in Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (Microtubule-Associated with Protein Tau): A Comparison of 123 I-IMP Brain Perfusion SPECT Analysis with Progressive Supranuclear Palsy.
Mov Disord. 2011 Feb 15;26(3):561-3.
28Oyama G, Shimo Y, Natori S, Nakajima M, Ishii H, Arai H, Hattori N:
Acute effects of bilateral subthalamic stimulation on decision-making in Parkinson's disease.
Parkinsonism Relat Disord. 2011 17;189-193.
29Sharma M, Maraganore DM, Ioannidis JP, Riess O, Aasly JO, Annesi G, Abahuni N, Bentivoglio AR, Brice A, Van Broeckhoven C, Chartier-Harlin MC, Destée A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Gispert S, Hattori N, Jasinska-Myga B, Klein C, Lesage S, Lynch T, Lichtner P, Lambert JC, Lang AE, Mellick GD, Nigris FD, Opala G, Quattrone A, Riva C, Rogaeva E, Ross OA, Satake W, Silburn PA, Theuns J, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Gasser T, Krüger R. Genetic Epidemiology of Parkinson's Disease Consortium.
Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease.
Neurobiol Aging 2011;32:2108.e1-5.
30Yamashiro K, Furuya T, Noda K, Urabe T, Hattori N, Okuma Y.
Convulsive movements in bilateral paramedian thalamic and midbrain infarction.
Case Rep Neurol 3:289-293, 2011
31Teramoto S, Miyamoto N, Yatomi K, Tanaka Y, Oishi H, Arai H, Hattori N, Urabe T.
Exendin-4, a glucagon-like peptide-1 receptor agonist, provides neuroprotection in mice transient focal cerebral ischemia.
J Cereb Blood Flow Metab 2011; 31: 1696-1705.
32Hassin-Baer S, Hattori N, Cohen O.S, Massarwa M, Israeli-Korn, S.D, Inzelberg, R.
Phenotype of the 202 Adenine Deletion in the parkin Gene: 40 Years of Follow-Up.
Movement Disorders, 26(4), 719-722. (2011). doi: Doi 10.1002/Mds.23456
33Kamagata K, Motoi Y, Shimogi K, Nakanishi A, Hori M, Mizuno Y, Hattori N, Aoki S.
Posterior hypoperfusioin Parkinson's disease and Parkinson's disease with dementia measured with arterial spin-labering MR imaging.
J MRI 33:803-807, 2011
34Krüger R, Sharma M, Riess O, Gasser T, Van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Klein C, Lambert JC, Lesage S, Lin JJ, Lynch T, Mellick GD, de Nigris F, Opala G, Prigione A, Quattrone A, Ross OA, Satake W, Silburn PA, Tan EK, Toda T, Tomiyama H, Wirdefeldt K, Wszolek Z,
Xiromerisiou G, Maraganore DM; for the Genetic Epidemiology of Parkinson's disease(GEOPD) consortium.
A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease.
Neurobiol Aging 2011;32:548.e9-18.
35Noda, K., Fukae, J., Fujishima, K., Mori, K., Urabe, T., Hattori, N., & Okuma, Y.
Reversible cerebral vasoconstriction syndrome presenting as subarachnoid hemorrhage, reversible posterior leukoencephalopathy, and cerebral infarction.
Intern Med, 50(11), 1227-1233, 2011
36Seki N, Takahashi Y, Tomiyama H, Rogaeva E, Murayama S, Mizuno Y, Hattori N, Marras C, Lang AE, George-Hyslop PS, Goto J, Tsuji S.
Comprehensive mutational analysis of LRRK2 reveals variants supporting association with autosomal dominant Parkinson's disease.
J Hum Genet 2011;56:671-5.
37Tomiyama H, Yoshino H, Ogaki K, Li L, Yamashita C, Li Y, Funayama M, Sasaki R, Kokubo Y, Kuzuhara S, Hattori N.
PLA2G6 variant in Parkinson’s disease.
J Hum Genet. 2011 May;56(5):401-3.
38Kambe T, Motoi Y, Inoue R, Kojima N, Tada N, Kimura T, Sahara N, Yamashita S, Mizoroki T, Takashima A, Shimada K, Ishiguro K, Mizuma H, Onoe H, Mizuno Y, Hattori N.
Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice.
Neurobiol Dis. 2011 Jun;42(3):404-14.
39Tomiyama H., Yoshino H, Hattori N.
Analysis of PLA2G6 in patients with frontotemporal type of dementia.
Parkinsonism & Related Disorders, 2011, 17(6), 493-494.
40Usami Y, Hatano T, Imai S, Kubo S, Sato S, Saiki S, Fujioka Y, Ohba Y, Sato F, Funayama M, Eguchi H, Shiba K, Ariga H, Shen J, Hattori N.
DJ-1 associates with synaptic membranes.
Neurobiology of Disease 43, 651-662, 2011.
41Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.
Autophagy 2011, 7:176-87
42Usui C, Hatta K, Doi N, Kubo S, Kamigaichi R, Nakanishi A, Nakamura H, Hattori N, Arai H.
Improvements in both psychosis and motor signs in Parkinson's disease, and changes in regional cerebral blood flow after electroconvulsive therapy.
Prog Neuropsychopharmacol Biol Psychiatry, 2011, 35(7), 1704-1708.
43Kawanabe T, Tanaka R, Sakaguchi Y, Akiyama O, Shimura H, Yasumoto Y, Ito M, Hattori N, Tanaka S.
Posterior reversible encephalopathy syndrome complicating intracranial hemorrhage after phenylpropanolamine exposure.
Neurol Med Chir (Tokyo). 2011;51(8):582-5.
44Ross OA, Soto-Ortolaza AI, Heckman MG, Aasly JO, Abahuni N, Annesi G, Bacon JA, Bardien S, Bozi M, Brice A, Brighina L, Van Broeckhoven C, Carr J, Chartier-Harlin MC, Dardiotis E, Dickson DW, Diehl NN, Elbaz A, Ferrarese C, Ferraris A, Fiske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM, Mellick GD, Mutez E, Nilsson C, Opala G, Park SS, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Theuns J, Tomiyama H, Uitti RJ, Valente EM, van de Loo S, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Farrer MJ; on behalf of the Genetic Epidemiology Of Parkinson's Disease (GEO-PD) Consortium.
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.
Lancet Neurol 2011;10:898-908.
45Takeichi T, Takarada-Iemata M, Hashida K, Sudo H, Okuda T, Kokame K, Hatano T, Takanashi M, Funabe S, Hattori N, Kitamura O, Kitao Y, Hori O.
The effect of Ndrg2 expression on astroglial activation.
Neurochem Int. 2011 Aug;59(1):21-7.
46Yasuda T, Hayakawa H, Nihira T, Ren YR, Nakata Y, Nagai M, Hattori N, Miyake K, Takada M, Shimada T, Mizuno Y, Mochizuki H.
Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.
J Neuropathol Exp Neurol 2011, 70(8), 686-697
47Morita A, Okuma Y, Kamei S, Yoshii F, Yamamoto T, Hashimoto S, Utsumi H, Hatano T, Hattori N, Matsumura M, Takahashi K, Nogawa S, Watanabe Y, Miyamoto T, Miyamoto M, Hirata K.
Pramipexole reduces the prevalence of fatigue in patients with Parkinson's disease.
Intern Med. 2011;50(19):2163-8.
48Tanaka R, Sasaki-Ikesawa K, Shimura H, Nishioka K, Hattori N, Tanaka S.
Methotrexate leukoencephalopathy mimics acute progressive stroke.
J Neurol. 2011;258(11):2083-5.
49Hayashi C, Funayama M, Li Y, Kawano A, Suzuki M, Hattori N, Ikeda K.
Prevalence of GJB2 Causing Recessive Profound Non-Syndromic Deafness in Japanese Children.
Int J Pediatr Otorhinolaryngol. 75:211-4, 2011.
50Benhammou JN, Vocke CD, Santani A, Schmidt LS, Baba M, Seyama K, Wu X, Korolevich S, Nathanson KL, Stolle CA, Linehan WM.
Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome.
Genes Chromosomes Cancer. 2011; 50(6):466-77.
51Hagiwara K, Morino H, Shiihara J, Tanaka T, Miyazawa H, Suzuki T, Kohda M, Okazaki Y, Seyama K, Kawakami H.
Homozygosity mapping on homozygosity haplotype analysis to detect recessive disease-causing genes from a small number of unrelated, outbred patients.
PLoS One. 2011; 6(9):e25059.
52Hayashi T, Kumasaka T, Mitani K, Terao Y, Watanabe M, Oide T, Nakatani Y, Hebisawa A, Konno R, Takahashi K, Yao T, Seyama K.
Prevalence of uterine and adnexal involvement in pulmonary lymphangioleiomyomatosis: a clinicopathologic study of 10 patients.
Am J Surg Pathol. 2011; 35(12): 1776-85.
53Hayashida M, Seyama K, Inoue Y, Hirai T, Mishima M;
Respiratory failure research group; Japanese Ministry of Health, Labor, and Welfare. Criteria for designation of lymphangioleiomyomatosis in the specified disease treatment research program.
Nihon Kokyuki Gakkai Zasshi. 2011; 49(2): 67-74.
54Honda A, Yanagawa M, Inoue A, Kikuyama A, Yoshida S, Sumikawa H, Tobino K, Koyama M, Tomiyama N.
Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction.
Br J Radiol. 2011; 84(1000): 335-41.
55Inomata M, Shukuya T, Takahashi T, Ono A, Nakamura Y, Tsuya A, Kenomotsu H, Naito T, Murakami H, Harada H, Endo M, Yamamoto N.
Continuous administration of EGFR-TKIs following radiotherapy after disease progression in bone lesions for non-small-cell lung cancer.
Anticancer Res. 2011; 31: 4519-23.
56Ishimoto T, Nagano O, Yae T, Tamada M, Motohara T, Oshima H, Oshima M, Ikeda T, Asaba R, Yagi H, Masuko T, Shimizu T, Ishikawa T, Kai K, Takahashi E, Imamura Y, Baba Y, Ohmura M, Suematsu M, Baba H, Saya H.
CD44 Variant regulates redox status in cancer cells by stabilizing the CT subunit of system xc- and thereby promotes tumor growth.
Cancer Cell. 2011; 19(8): 387-400.
57Ishiwata T, Hirose T, Hirama M, Miura K, Iwakami S, Tominaga S, Adachi M, Takahashi K.
A feasibility study of zoledronic acid combined with carboplatin/nedaplatin plus paclitaxel in patients with non-small cell lung cancer with bone metastases.
Tumori. 2011; 97:568-572.
58Ito J, Harada N, Nagashima O, Makino F, Usui Y, Yagita H, Okumura K, Dorscheid R. D, Atsuta R, Akiba H, Takahashi K.
Wound-induced TGF-β1 and TGF-β2 enhance airway epithelial repair via HB-EGF and TGF-α.
Biochemical and Biophysical Research Communications. 2011; 412:109-114.
59Kaira K, Oriuchi N, Takahashi T, Nakagawa K, Ohde Y, Okumura T, Murakami H, Shukuya T, Kenmotsu H, Naito T, Kanai Y, Endo M, Kondo H, Nakajima T, Yamamoto N.
L-type amino acid transporter 1 (LAT1) expression in malignant pleural mesothelioma.
Anticancer Res. 2011; 31: 4075-82.
60Kaira K, Takahashi T, Murakami H, Shukuya T, Kenmotsu H, Naito T, Oriuchi N, Kanai Y, Endo M, Kondo H, Nakajima T, Yamamoto N. 
Relationship between LAT1 expression and response to platinum-based chemotherapy in non-small cell lung cancer patients with postoperative recurrence.
Anticancer Res. 2011; 31: 3775-82.
61Kaira K, Oriuchi N, Takahashi T, Nakagawa K, Ohde Y, Okumura T, Murakami H, Shukuya T, Kenmotsu H, Naito T, Kanai Y, Endo M, Kondo H, Nakajima T, Yamamoto N.
LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer.
Am J Transl Res. 2011; 3: 468-78.
62Kanaji N, Sato T, Nelson A, Wang X, Li Y, Kim M, Nakanishi M, Basma H, Michalski J, Farid M, Chandler M, Pease W, Patil A, Rennard SI, Liu X.
Inflammatory cytokines regulate endothelial cell survival and tissue repair functions via NF-kB signaling.
J Inflamm Res. 2011; 4: 127-38.
63Kato M, Shiota S, Shiga K, Takagi H, Mori H, Sekiya M, Suzuki K, Uekusa T, Takahashi K.
Benign giant mediastinal schwannoma presenting as cardiac tamponade in a woman: a case report.
J Med Case Rep. 2011; 14(5): 61.
64Kenmotsu H, Naito T, Kimura M, Ono A, Shukuya T, Nakamura Y, Tsuya A, Kaira K, Murakami H, Takahashi T, Endo M, Yamamoto N.
The Risk of Cytotoxic chemotherapy-related exacerbation of interstitial lung disease with lung cancer.
J Thorac Oncol. 2011; 6(7): 1242-6.
65Li YJ, Wang XQ, Sato T, Kanaji N, Nakanishi M, Kim M, Michalski J, Nelson AJ, Sun JH, Farid M, Basma H, Patil A, Toews Ml, Liu X, Rennard SI.
Prostaglandin E2 inhibits human lung fibroblast chemotaxis through disparate actions on different E-prostanoid receptors.
Am J Respir Cell Mol Biol. 2011; 44(1): 99-107.
66Motohara T, Masuko S, Ishimoto T, Yae T, Onishi N, Muraguchi T, Hirao A, Matsuzaki Y, Tashiro H, Katabuchi H, Saya H, Nagano O.
Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells.
Carcinogenesis. 2011; 32(11): 1597-606.
67Nagahama K, Hayashi T, Nagaoka T, Kanemaru R, Togo S, Kumasaka T, Uekusa T, Seyama K, Takahashi K.
Pulmonary erdheim-chester disease: A response to predonisolone.
Respiratory Medicine CME. 2011; 4: 81-84.
68Ohwada A, Inami K, Matsumoto- Yamazaki M, Atsuta R, Takahashi K.
Bronchial reversibility with a short-acting β2-agonist predicts the FEV1 response to administration of a along-acting β2-agonist with inhaled corticosteroids in patients with bronchial asthma.
Experimental and Therapeutic Medicine. 2011; 2: 619-623.
69Ohashi R, Kato M, Katsura Y, Takekawa H, Hoshika Y, Sugawara T, Yoshimi K, Togo S, Nagaoka T, Seyama K, Takahashi K, Tsuchiya K, Misawa S, Kikuchi K.
Breakthrough lung scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance(MGUS).
Med. Mycol. J. 2011; 52:33-38.
70Sato T, Liu X, Basma H, Togo S, Sugiura H, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Michalski J, Farid M, Sharp JG, Rennard SI.
Interleukin-4 induces differentiation of human embryonic stem cells into“fibrogenic”fibroblast-like cells.
J Allergy Clin Immun. 2011; 127: 1595-1603.
71Shiomi K, Shiomi S, Ishinaga Y, Sakuraba M, Hagiwara Y, Miyashita K, Maeda M, Suzuki K, Takahashi K, Hino O.
Impact of renal failure on the tumor markers of mesothelioma, N-ERC/mesothelin and osteopontin.
Anticancer Research. 2011; 31:1427-1430.
72Shukuya T, Takahashi T, Kaira R, Ono A, Nakamura Y, Tsuya A, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Takahashi K, Yamamoto N.
Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: a pooled analysis of published reports.
Cancer Sci. 2011; 102(5): 1032-1037.
73Shukuya T, Takahashi T, Naito T, Kaira R, Ono A, Nakamura Y, Tsuya A, Kenmotsu H, Murakami H, Harada H, Mitsuya K, Endo M, Nakasu Y, Takahashi K, Yamamoto N.
Continuous EGFR-TKI administration following radiotherapy for non-small cell lung cancer patients with isolated CNS failure.
Lung Cancer. 2011; 74(3): 457-61.
74Tajima K, Miura K, Ishiwata T, Takahashi F, Yoshioka M, Minakata K, Murakami A, Sasaki S, Iwakami S, Annoura T, Hashimoto M, Nara T, Takahashi K.
Sex hormones alter Th1 responses and enhance granuloma formation in the lung.
Respiration. 2011; 81(6): 491-498.
75Takahashi F, Chiba N, Tajima K, Hayashida T, Shimada T, Takahashi M, Moriyama H, Brachtel E, Edelman EJ, Ramaswamy S, Maheswaran S.
Breast tumor progression induced by loss of BTG2 expression is inhibited by targeted therapy with the ErbB/HER inhibitor lapatinib.
Oncogene. 2011; 30(27): 3084-95.
76Tobino K, Gunji Y, Kurihara M, Kunogi M, Koike K, Tomiyama N, Johkoh T, Kodama Y, Iwakami S, Kikkawa M, Takahashi K. Seyama K.
Characteristics of pulmonary cysts in Birt-Hogg-Dubé syndrome: thin-section CT findings of the chest in 12 patients.
Eur J Radiol. 2011; 77(3):403-409.
77Togo S, Sato T, Sugiura H, Wang X, Basma H, Nelson A, Liu X, Bargar TW, Sharp JG, Rennard SI.
Differentiation of embryonic stem cells into fibroblast-like cells in three-dimensional type I collagen gel cultures.
In Vitro Cell Dev Biol Animal. 2011; 47(2): 114-24.
78Tsutsui A, Suzuki S, Yamane K, Matsui M, Konda T, Marui E, Takahashi K, Arakawa Y.
Genotypes and infection sites in an outbreak of multidrug-resistant Pseudomonas aeruginosa.
J Hosp Infect. 2011; 78(4):317-22.
79Ning L, Ishijima M, Kaneko H, Kurihara H, Arikawa-Hirasawa E, Kubota M, Liu L, Xu Z, Futami I, Yusup A, Miyahara K, Xu S, Kaneko K, Kurosawa H,
Correlations between both the expression levels of inflammatory mediators and growth factor in medial perimeniscal synovial tissue and the severity of medial knee osteoarthritis,
Int. Orthop.2011 Jun;35 :831-8.
80Chyba M, Mercier F, RaderJ, Douet V Arikawa-Hirasawa E, Kwon YC, Kodama R
Dynamic mathematical modeling of cell-fractone interactions 
Journal of Math-for-Industry, Vol. 3, pp. 79–88
81Kiyanagi T, Iwabuchi K, Shimada K, Hirose K, Miyazaki T, Sumiyoshi K, Iwahara C, Nakayama H, Masuda H, Mokuno H, Sato S, Daida H.
Involvement of Cholesterol-enriched Microdomains in Class A Scavenger Receptor-mediated Responses in Human Macrophages.
Atherosclerosis. 215:60-69;2011.
82Hirose K, Iwabuchi K, Shimada K, Kiyanagi T, Iwahara C, Nakayama H, Daida H.
Different responses to oxidized low-density lipoproteins in human polarized macrophages.
Lipids Health Dis. 10:1;2011.
83Maruyama S, Shibata R, Ohashi K, Ohashi T, Daida H, Walsh K, Murohara T, Ouchi N.
Adiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanism.
J Biol Chem. 286:32790-800;2011.
84Dohi T, Miyauchi K, Iesaki T, Tsuruta R, Tsuboi S, Ogita M, Kubota N, Kasai T, Yokoyama T, Daida H.
Candesartan with pioglitazone protects against endothelial dysfunction and inflammatory responses in porcine coronary arteries implanted with sirolimus-eluting stents.
Circ J. 75:1098-106;2011.
85Fukao K, Shimada K, Hiki M, Kiyanagi T, Hirose K, Kume A, Ohsaka H, Matsumori R, Kurata T, Miyazaki T, Daida H.
Effects of calcium channel blockers on glucose tolerance, inflammatory state, and circulating progenitor cells in non-diabetic patients with essential hypertension: a comparative study between Azelnidipine and amlodipine on Glucose tolerance and Endothelial functioN - a crossover Trial (AGENT).
Cardiovasc Diabetol. 79:10;2011
86Nishitani M, Shimada K, Sunayama S, Masaki Y, Kume A, Fukao K, Sai E, Yamashita H, Ohmura H, Onishi T, Shioya M, Sato H, Shimada A, Yamamoto T, Amano A, Daida H.
Impact of diabetes on muscle mass, muscle strength, and exercise tolerance in patients after coronary artery bypass grafting.
J Cardiol. 58:173-180;2011.
87Yaginuma K, Kasai T, Miyauchi K, Kajimoto K, Amano A, Daida H.
Propensity score analysis of 10-year long-term outcome after bypass surgery or plain old balloon angioplasty in patients with metabolic syndrome.
Int Heart J. 52:372-6;2011.
88Ogita M, Miyauchi K, Dohi T, Wada H, Tuboi S, Miyazaki T, Nishino A, Yokoyama T, Kojima T, Yokoyama K, Kurata T, Daida H.
Gender-based outcomes among patients with diabetes mellitus after percutaneous coronary intervention in the drug-eluting stent era.
Int Heart J. 52:348-52;2011.
89Dohi T, Miyauchi K, Okazaki S, Yokoyama T, Ohkawa R, Nakamura K, Yanagisawa N, Tsuboi S, Ogita M, Yokoyama K, Kurata T, Yatomi Y, Daida H. Dohi T, Miyauchi K, Okazaki S, Yokoyama T, Ohkawa R, Nakamura K, Yanagisawa N, Tsuboi S, Ogita M, Yokoyama K, Kurata T, Yatomi Y, Daida H.
Decreased circulating lipoprotein-associated phospholipase A2 levels are associated with coronary plaque regression in patients with acute coronary syndrome.
Atherosclerosis. 219:907-12;2011.
90Nishino A, Kasai T, Miyauchi K, Nakajima N, Yokoyama T, Yokoyama K, Kurata T, Daida H.
Long-term effect of metabolic syndrome with and without diabetes mellitus on coronary revascularization in Japanese patients undergoing percutaneous coronary intervention.
Clin Cardiol. 34:610-6;2011.
91Hibi K, Kimura T, Kimura K, Morimoto T, Hiro T, Miyauchi K, Nakagawa Y, Yamagishi M, Ozaki Y, Saito S, Yamaguchi T, Daida H, Matsuzaki M; JAPAN-ACS Investigators.
Clinically evident polyvascular disease and regression of coronary atherosclerosis after intensive statin therapy in patients with acute coronary syndrome: serial intravascular ultrasound from the Japanese assessment of pitavastatin and atorvastatin in acute coronary syndrome (JAPAN-ACS) trial.
Atherosclerosis. 219:743-9;2011.
92Ogita M, Miyauchi K, Kurata T, Yokoyama K, Dohi T, Tuboi S, Miyazaki T, Nishino A, Yokoyama T, Daida H.
Clinical impact of angiographic restenosis after bare-metal stent implantation on long-term outcomes in patients with coronary artery disease.
Circ J. 75:2566-72;2011.
93Teramoto T, Kitagawa Y, Daida H; APPROACH-J Study group.
APPROACH-J study: design, rationale, and baseline data of the affirmation primary prevention with pravastatin in reduction of occlusive atherosclerotic complications in hypercholesterolemia--Japan study.
J Atheroscler Thromb.18:1054-61;2011.
94Kohro T, Yamazaki T, Izumi T, Daida H, Kurabayashi M, Miyauchi K, Tojo T, Nagai R; JCADII Investigators.
Intensively lowering both low-density lipoprotein cholesterol and blood pressure does not reduce cardiovascular risk in Japanese coronary artery disease patients.
Circ J. 75:2062-70;2011.
95Sato H, Kasai T, Miyauchi K, Kubota N, Kajimoto K, Miyazaki T, Nishino A, Yaginuma K, Tamura H, Kojima T, Yokoyama K, Kurata T, Amano A, Daida H.
Long-term outcomes of women with coronary artery disease following complete coronary revascularization.
J Cardiol. 58:158-64:2011.
96Konishi H, Kasai T, Miyauchi K, Kajimoto K, Kubota N, Dohi T, Amano A, Daida H.
Association of low glomerular filtration rate with the incidence of stroke in patients following complete coronary revascularization.
Circ J. 75:2372-8;2011.
97Fukushima Y, Hirayama S, Ueno T, Dohi T, Miyazaki T, Ohmura H, Mokuno H, Miyauchi K, Miida T, Daida H.
Small dense LDL cholesterol is a robust therapeutic marker of statin treatment in patients with acute coronary syndrome and metabolic syndrome.
Clin Chim Acta. 412:1423-7;2011.
98Yokoyama K, Miyauchi K, Kawamura M, Kajimoto K, Dohi T, Yamagami S, Kano T, Amano A, Hosoda Y, Daida H.
String-sign in left internal thoracic artery is associated with regression in left main trunk stenosis after coronary artery bypass.
Int Heart J. 52:84-7;2011.
99Kojima T, Miyauchi K, Yokoyama T, Yokoyama K, Kurata T, Suwa S, Kawamura M, Tamura H, Okazaki S, Inoue K, Fujiwara Y, Sumiyoshi M, Tanimoto K, Nakazato Y, Yamagami S, Hiro T, Komiyama N, Daida H.
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo University (ALPS-J).
Circ J. 75:1071-9;2011.
100Masaki Y, Shimada K, Kojima T, Miyauchi K, Inoue K, Kiyanagi T, Hiki M, Fukao K, Hirose K, Ohsaka H, Kume A, Miyazaki T, Ohmura H, Ohsaka A, Daida H.
Clinical significance of the measurements of plasma N-terminal pro-B-type natriuretic peptide levels in patients with coronary artery disease who have undergone elective drug eluting stent implantation.
J Cardiol. 57:303-310;2011.
101Dohi T, Miyauchi K, Okazaki S, Yokoyama T, Tamura H, Kojima T, Yokoyama K, Kurata T, Daida H.
Long-term impact of mild chronic kidney disease in patients with acute coronary syndrome undergoing percutaneous coronary interventions.
Nephrol Dial Transplant. 26:2906-11;2011.
102Kasai T, Miyauchi K, Kajimoto K, Kubota N, Dohi T, Tsuruta R, Ogita M, Yokoyama T, Amano A, Daida H.
Prognostic significance of glomerular filtration rate estimated by the Japanese equation among patients who underwent complete coronary revascularization.
Hypertens Res. 34:378-83;2011.
103Dohi T, Miyauchi K, Okazaki S, Yokoyama T, Yanagisawa N, Tamura H, Kojima T, Yokoyama K, Kurata T, Daida H.
Plaque regression determined by intravascular ultrasound predicts long-term outcomes of patients with acute coronary syndrome. J Atheroscler
Thromb. 18:231-9;2011.
104Kuwahara Y, Oikawa T, Ochiai Y, Roudkenar MH, Fukumoto M, Shimura T, OhtakeY, Ohkubo Y, Mori S, Uchiyama Y, Fukumoto M (2011)
nhancement of autophagy is a potential modality for tumors refractory to radiotherapy.
Cell Death Dis, 2:e177
105Shiozaki M, Hayakawa N, Shibata M, Koike M, Uchiyama Y, Gotow T (2011)
Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice.
Histochem Cell Biol, 136:475–489
106Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H (2011)
Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice.
Proc Natl Acad Sci USA 108: 16825-16830
107Uchida Y, Hasegawa J, Chinnapen D, Inoue T, Okazaki S, Kato R, Wakatsuki S, Misaki R, Koike M, Uchiyama Y, Iemura S, Natsume T, Kuwahara R, Nakagawa T, Nishikawa K, Mukai K, Miyoshi E, Taniguchi N, Sheff D, Lencer WI, Taguchi T, Arai H (2011)
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.
Proc Natl Acad Sci USA 108:15846-15851
108Koyanagi M, Asahara A, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Hosooka T, Inoue H, Matsumoto H, Koike M, Uchiyama Y, NodaT, Seino S, Kasuga M, Kido Y (2011)
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
PLoS One 6:e23238
109Oguro M, Koike M, Ueno T, Asaoka D, Mori H, Nagahara A, Uchiyama Y, Watanabe S (2011)
Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease.
J Gastroenterol, 46:629-638

英文原著(2010年)

1Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R (2010)
Reduction of brain b-amyloid by fluvastatin, a hydroxymethylglutaryl- CoA reductase inhibitor, through increase in degradation of amyloid precursor protein Cterminal fragments (APP-CTFs) and Ab-clearance.
J Biol Chem 285: 22091-22102
2Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H (2010)
Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A stimulated microglial.
Glia 58: 114-124
3Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H (2010)
Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.
Biochem Biophys Res Comm 399: 391-395
4Lee J-H, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Wolfe DM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Cuervo AM, Nixon RA (2010)
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Cell 141:1146-1158
5Tizon B, Sahoo S, Yu H, Gauthier S, Kumar AR, Mohan P, Figliola M, Pawlik M, Grubb A, Uchiyama Y, Bandyopadhyay U, Cuervo AM, Nixon RA, Levy E. (2010)
Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.
PMID: 20541250
6Hadano S, Otomo A, Kunita R, Suzuki-Utsunomiya A, Akatsuka A, Koike M, Aoki M, Uchiyama Y, Itoyama Y, Ikeda JE (2010)
Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking.
PLoS One 5:e9805.
7Shimada N, Ohno-Matsui K, Iseki S, Koike M, Uchiyama Y, Wang J, Yoshida T, Sato T, Peters C, Mochizuki M, Morita I (2010)
Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization.
Am J Pathol 176:2571-2580
8Shibata M, Yoshimura K, Tamura H, Ueno T, Nishimura T, Inoue T, Sasaki M, Koike M, Arai H, Kominami E, Uchiyama Y (2010)
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation.
Biophys Biochem Res Comm 393:274-279
9Yagita Y, Horie K, Yamanaka I, Koinuma S, Shigeyoshi Y, Kawakami K, Takeda J, Uchiyama Y (2010)
Chondrogenesis during the ES cell differentiation in vitro.
PNAS 107:3846-3851
10Tamura H, Shibata M, Koike M, Sasaki M, Uchiyama Y (2010)
Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains.
J Histochem Cytochem 58: 443-453
11Tatsumi K, Sou Y-S, Tada N, Nakamura E, Iemura S, Natsume T, Kang SH, Chung CH, Kasahara M, Kominami E, Yamamoto M, Tanaka K, Komatsu M.
A novel type of E3-ligase for the Ufm1-conjugation system.
J Biol Chem. 2010 Feb; 285(8): 5417-5427.
12Fukao K, Shimada K, Naito H, Sumiyoshi K, Inoue N, Iesaki T, Kume A, Kiyanagi T, Hiki M, Hirose K, Matsumori R, Ohsaka H, Takahashi Y, Toyoda S, Itoh S, Miyazaki T, Tada N, Daida H.
Voluntary exercise ameliorates the progression of atherosclerotic lesion formation via anti-inflammatory effects in apolipoprotein E-deficient mice.
J Atheroscler Thromb. 2010 Dec; 17(12): 1226-1236.
13Kuerban B, Shibata N, Komatsu M, Ohnuma T, Arai H. 
Genetic association between PLTP gene polymorphisms and Alzheimer's disease in a Japanese population.
Dement Geriatr Cogn Disord. 2010:30(1):78-82.
14Murayama N, Iseki E, Fujishiro H, Yamamoto R, Ota K, Suzuki M, Nagashima K, Arai H, Sato K.
Detection of early amnestic mild cognitive impairment without significantly objective memory impairment: a case-controlled study.
Psychogeriatrics. 2010:10:62-68.
15Fujishiro H, Iseki E, Murayama N, Yamamoto R, Higashi S, Kasanuki K, Suzuki M, Arai H, Sato K.
Diffuse occipital hypometabolism on [18 F]-FDG PET scans in patients with idiopathic REM sleep behavior disorder: prodromal dementia with Lewy bodies?
Psychogeriatrics. 2010:10:144-152.
16Fujishiro H, Iseki E, Higashi S, Kasanuki K, Murayama N, Togo T, Katsuse O, Uchikado H, Aoki N, Kosaka K, Arai H, Sato K.
Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia.
Neurosci Lett. 2010:3;486:19-23.
17Ota T, Shinotoh H, Fukushi K, Kikuchi T, Sato K, Tanaka N, Shimada H, Hirano S, Miyoshi M, Arai H, Suhara T, Irie T.
Estimation of plasma IC50 of donepezil for cerebral acetylcholinesterase inhibition in patients with Alzheimer disease using positron emission tomography.
Clin Neuropharmacol. 2010:33:74-78.
18Baba K, Baba H, Noguchi I, Arai R, Suzuki T, Mimura M, Arai H.
Executive dysfunction in remitted late-life depression - Juntendo University Mood Disorder Projects: JUMP.
J Neuropsychiatry Clin Neurosci. 2010:22:70-74.
19Shibata N, Kuerban B, Komatsu M, Ohnuma T, Baba H, Arai H.
Genetic Association Between CALHM1, 2, and 3 Polymorphisms and Alzheimer's Disease in a Japanese Population. 
J Alzheimers Dis. 2010:20(2):417-21.
20Tatsumi K, Sou Y-S, Tada N, Nakamura E, Iemura S, Natsume T, Kang SH, Chung CH, Kasahara M, Kominami E, Yamamoto M, Tanaka K, Komatsu M.
A novel type of E3-ligase for the Ufm1-conjugation system.
J Biol Chem. 2010 Feb; 285(8): 5417-5427.
21Fukao K, Shimada K, Naito H, Sumiyoshi K, Inoue N, Iesaki T, Kume A, Kiyanagi T, Hiki M, Hirose K, Matsumori R, Ohsaka H, Takahashi Y, Toyoda S, Itoh S, Miyazaki T, Tada N, Daida H.
Voluntary exercise ameliorates the progression of atherosclerotic lesion formation via anti-inflammatory effects in apolipoprotein E-deficient mice.
J Atheroscler Thromb. 2010 Dec; 17(12): 1226-1236.
22Nakano T.,Kitazawa S.
Eyeblink entrainment at breakpoints of speech.
Exp Brain Res. 205: 577-81, 2010.
23Genko Oyama, Kenji Yoshimi, Shihoko Natori, Yoko Chikaoka, Yong-Ri Ren, Manabu Funayama, Yasushi Shimo, Ryosuke Takahashi, Taizo Nakazato, Shigeru Kitazawa, Nobutaka Hattori.
Impaired in vivo dopamine release in parkin knockout mice.
Brain Res. 1352: 214-22, 2010.
24Kumano H, Uka T.
The spatial profile of macaque MT neurons is consistent with Gaussian sampling of logarithmically coordinated visual representation.
J Neurophysiol. 104: 61-75, 2010.
25Nakano T, Tanaka K, Endo Y, Yamane Y, Yamamoto T, Nakano Y, Ota H, Kato N, Kitazawa S.
Atypical gaze patterns in children and adults with autism spectrum disorders dissociated from developmental changes in gaze behaviour.
Proc. R. Proc Biol Sci. 277: 2935-43, 2010.
26Wada M, Higo N, Moizumi S, Kitazawa S.
c-Fos expression during temporal order judgment in mice.
Plos One 5: e10483, 2010.
27Shiotsuki H, Yoshimi K, Shimo Y, Funayama M, Takamatsu Y, Ikeda K, Takahashi R, Kitazawa S, Hattori N.
A rotarod test for evaluation of motor skill learning.
Journal of Neuroscience Methods 189: 180-185, 2010.
28Inoue M and Mikami A.
Feature to space conversion during target selection in the dorsolateral and ventrolateral prefrontal cortex of monkeys.
Eur. J. Neurosci. 31: 938-949, 2010.
29Katai S, Kato K, Unno S, Kan Y, Saruwatari M, Ishikawa N, Inoue M, and Mikami A.
Classification of extracellularly recorded neurons by their discharge patterns and their correlates with intracellularly identified neuronal types in the frontal cortex of behaving monkeys.
Eur. J. Neurosci. 31: 1322-1338, 2010.
30Ono F & Kitazawa S.
The effect of perceived motion-in-depth on time perception.
Cognition 115: 140-146, 2010.
31Wada M, Watanabe S, Chung U, Higo N, Taniguchi T, Kitazawa S.
Noninvasive bioluminescence imaging of c-fos expression in the mouse barrel cortex.
Behavioural Brain Research 208: 158-162, 2010.
32Nakano T, Ota H, Kato N & Kitazawa S.
Deficit in visual temporal integration in autism spectrum disorders.
Proc. R. Soc. Lond. B 277: 1027-30, 2010.
33Ono F & Kitazawa S.
Shortening of subjective tone intervals followed by repetitive tone stimuli.
Atten Percept Psychophys 72: 492-500, 2010.
34Evangelou E, Maraganore DM, Annesi G, Brighina L, Brice A, Elbaz A, Ferrarese C, Hadjigeorgiou GM, Krueger R, Lambert JC, Lesage S, Markopoulou K, Mellick GD, Meeus B, Pedersen NL, Quattrone A, Van Broeckhoven C, Sharma M, Silburn PA, Tan EK, Wirdefeldt K, Ioannidis JP; for the Genetic Epidemiology of Parkinson's Disease (GEOPD) Consortium: includes Hattori N, and Checkoway H.
Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: Large-scale collaborative study.
Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):220-8.
35Mitsui J, Takahashi Y, Goto J, Tomiyama H, Ishikawa S, Yoshino H, Minami N, Smith DI, Lesage S, Aburatani H, Nishino I, Brice A, Hattori N, Tsuji S.
Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines.
Am J Hum Genet 2010;87:75-89.
36Shiotsuki H, Yoshimi K, Shimo Y, Funayama M, Takamatsu Y, Ikeda K, Takahashi R, Kitazawa S, Hattori N.
A rotarod test for evaluation of motor skill learning.
J Neurosci Methods 2010;189:180-5.
37Ueno Y, Shimada Y, Tanaka R, Miyamoto N, Tanaka Y, Hattori N, Urabe T.
Patent foramen ovale with atrial septal aneurysm may contribute to white matter lesions in stroke patients.
Cerbrovasc Dis 30: 15-22, 2010.
38Miyamoto N, Tanaka R, Shimura H, Watanabe T, Mori H, Onodera M, Mochizuki H, Hattori N, Urabe T.
Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain.
J Cereb Blood Flow Metab. 2010 Feb;30(2):299-310.
39Kawajiri S, Machida Y, Saiki S, Sato S, Hattori N.
Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD.
Neurosci Lett. 2010 Sep 6;481(2):88-91.
40Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K.
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
J Cell Biol. 2010 Apr 19;189(2):211-21.
41Miyamoto N, Tanaka R, Shimura H, Watanabe T, Mori H, Onodera M, Mochizuki H, Hattori N, Urabe T.
Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain.
J Cereb Blood Flow Metab. 2010 Feb;30(2):299-310.
42Oyama G, Yoshimi K, Natori S, Chikaoka Y, Ren YR, Funayama M, Shimo Y, Takahashi R, Nakazato N, Kitazawa S, Hattori N.
Impaired in vivo dopamine release in parkin knockout mice.
Brain Research 1352:214-22, 2010.
43Kambe T, Motoi Y, Ishii K, Hattori N.
Posterior cortical atrophy with [11C] Pittsburgh compound B accumulation in the primary visual cortex.
J Neurol. 2010 Mar;257(3):469-71.
44Kawanabe T, Yoritaka A, Shimura H, Oizumi H, Tanaka S, Hattori N.
Successful treatment with Yokukansan for behavioral and psychological symptoms of Parkinsonian dementia.
Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17;34(2):284-7.
45Li L, Funayama M, Tomiyama H, Li Y, Yoshino H, Sasaki R, Kokubo Y, Kuzuhara S, Mizuno Y, Hattori N.
No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients.
Neurosci Lett. 2010 Aug 2;479(3):245-8
46Noda K, Tani M, Fukae J, Fujishima K, Hattori N, Okuma Y.
Isolated proximal leg paresis due to a small cortical infarction.
Intern Med. 2010;49(15):1633-6.
47Fukae J, Noda K, Fujishima K, Takahashi T, Hattori N, Okuma Y.
Subacute longitudinal myelitis associated with Behcet's disease.
Intern Med. 2010;49(4):343-7.
48Fukae J, Tanaka S, Hattori N.
Retroperitoneal fibrosis secondary to pergolide therapy.
Intern Med. 2010;49(15):1687.
49Shiotsuki H, Yoshimi K, Shimo Y, Funayama M, Takamatsu Y, Ikeda K, Takahashi R, Kitazawa S, Hattori N.
A rotarod test for evaluation of motor skill learning.
J Neurosci Methods. 2010 Jun 15;189(2):180-5.
50Kawanabe T, Yoritaka A, Shimura H, Oizumi H, Tanaka S, Hattori N.
Successful treatment with Yokukansan for behavioral and psychological symptoms of Parkinsonian dementia.
Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17;34(2):284-7
51Shiotsuki H, Motoi Y, Nakamura S, Mizuno Y, Hattori N.
Dopamine deficiency may lead to Capgras syndrome in parkinson’s disease with dementia,
J Neuropsychiatry Clin Neurosci. 2010 Summer;22(3):352i.e14-352.e15.
52Xu Z, Ichikawa N, Kosaki K, Yamada Y, Sasaki T, Sakai LY Kurosawa H, Hattori N, Arikawa-Hirasawa E.
Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition.
Matrix Biol.2010 Jul;29(6):461-70.
53Yamashiro K, Milsom AB, Duchene J, Panayiotou C, Urabe T, Hattori N, Ahluwalia A.
Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice.
J Cereb Blood Flow Metab. 2010 Aug;30(8):1494-503.
54Miyamoto N, Tanaka Y, Ueno Y, Tanaka R, Hattori N, Urabe T.
Comparison of clinical backgrounds with anterior versus posterior circulation infarcts.
J Stroke Cerebrovasc Dis. 2010 Sep-Oct;19(5):393-7.
55Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N.
PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.
FEBS Lett. 2010 Mar 19;584(6):1073-9.
56Miyamoto N, Tanaka Y, Ueno Y, Tanaka R, Hattori N, Urabe T.
Comparison of clinical backgrounds with anterior versus posterior circulation infarcts.
J Stroke Cerebrovasc Dis. 2010 Sep-Oct;19(5):393-7.
57Ogaki K, Noda K, Fukae J, Furuya T, Hirayama T, Fujishima K, Hattori N, Okuma Y.
Cryptococcal meningitis successfully treated with liposomal amphotericin B and voriconazole in an elderly patient.
Brain Nerve 2010;62:1337-40.
58Tanaka Y, Tanaka R, Liu M, Hattori N, Urabe T.
Cilostazol attenuates ischemic brain injury and enhances neurogenesis in the subventricular zone of adult mice after transient focal cerebral ischemia.
Neuroscience 171: 1367-1376, 2010.
59Yoshino H, Tomiyama H, Tachibana N, Ogaki K, Li Y, Funayama M, Hashimoto T, Takashima S, Hattori N.
Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism.
Neurology. 2010 Oct 12;75(15):1356-61.
60Funayama M, Tomiyama H, Wu RM, Ogaki K, Yoshino H, Mizuno Y, Hattori N.
Rapid screening of ATP13A2 variant with high-resolution melting analysis.
Mov Disord 2010;25:2434-7.
61Lesage S, Patin E, Condroyer C, Leutenegger AL, Lohmann E, Giladi N, Bar-Shira A, Belarbi S, Hecham N, Pollak P, Ouvrard-Hernandez AM, Bardien S, Carr J, Benhassine T, Tomiyama H, Pirkevi C, Hamadouche T, Cazeneuve C, Basak AN, Hattori N, Dürr A, Tazir M, Orr-Urtreger A, Quintana-Murci L, Brice A.
arkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans.
Hum Mol Genet 2010;19:1998-2004.
62Sekine T, Kagaya H, Funayama M, Li Y, Yoshino H, Tomiyama H, Hattori N.
Clinical course of the first Asian family with Parkinsonism related to SNCA triplication.
Mov Disord 2010;25:2871-75.
63Watanabe M, Kimura K, Iguchi Y, Shibazaki K, Urabe T, Hattori N.
Peripheral arterial atherosclerosis in patients with extracranial, not intracranial, arterial stenosis.
Intern Med. 2010;49(15):1515-9.
64Hayashi T, Kumasaka T, Mitani K, Yao T, Suda K, Seyama K.
Loss of heterozygosity on tuberous sclerosis complex genes in multifocal micronodular pneumocyte hyperplasia.
Mod Pathol. 2010; 23: 1251-1260.
65Hayashida T, Takahashi F, Chiba N, Brachtel E, Takahashi M, Godin-Heymann N, Gross KW, Vivanco MM, Wijendran V, Shioda T, Sgroi D, Donahoe PK, Maheswaran S.
HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis. (* First two authors contributed equally to this work.)
Proc Natl Acad Sci USA. 2010; 107(3):1100-5.
66Huqun, Fukuyama S, Morino H, Miyazawa H, Tanaka T, Suzuki T, Kohda M, Kawakami H, Okazaki Y, Seyama K, Hagiwara K.
A quantitatively-modeled homozygosity mapping algorithm, qHomozygosityMapping, utilizing whole genome single nucleotide polymorphism genotyping data.
BMC Bioinformatics 11 Suppl. 2010; 7:S5.
67Ichikawa M, Iwakami S, Fujii M, Takahashi K.
A Rare image of a pulmonary nodule revealed on FDG-PET scans.
Inter Med. 2010; 49: 2275-2276.
68shiwata T, Sekiya M, Suzuki T, Matsuoka T, Kumasaka T, Takahashi K.
Thymic adenocarcinoma with sarcomatoid features characterized by intracaval tumor growth: report of a case.
Surg Today. 2010; 40: 1068-1072.
69Ichinose M, Seyama K, Nishimura M, Fukuchi Y, Nagai A, Mishima M, Kubo K; Beta-2 Agonist Research and Evaluation Committee in COPD (BAREC) Study Group.
Additive effects of transdermal tulobuterol to inhaled tiotropium in patients with COPD.
Respir Med. 2010; 104: 267-274.
70Igawa S, Murakami H, Takahashi T, Nakamura Y, Tsuya A, Naito T, Kaira K, Ono A, Shukuya T, Tamiya A, Endo M, Yamamoto N.
Efficacy of chemotherapy with carboplatin and paclitaxel for unresectable thymic carcinoma.
Lung Cancer. 2010; 67:194-197.
71Jiang DM, Kato C, Zhou XW, Wu ZH, Sato T, Li YZ.
Phylogeographic separation of marine ando soil myxobacteria ato high levels of classification.
ISME J. 2010; 4(12): 1520-1530.
72Kaira K, Naito T, Takahashi T, Ayabe E, Shimoyama R, Kaira R, Ono A, Igawa S, Shukuya T, Murakami H, Tsuya A, Nakamura Y, Endo M, Yamamoto N.
Pooled analysis of the reports of erlotinib after failure of gefitinib for non-small cell lung cancer.
Lung Cancer. 2010; 68: 99-104.
73Kamio K, Liu XD, Sugiura H, Togo S, Kawasaki S, Wang X, Ahn Y, Hogaboam C, Rennard SI.
Statins inhibit matrix metalloproteinase release from human lung fibroblasts.
Eur Respir J. 2010; 35(3):637-46.
74Koike K, Kondo Y, Sekiya M, Sato Y, Tobino K, Iwakami S, Goto S, Takahashi K, Maruyama N, Seyama K, Ishigami A.
Complete lack of vitamin C intake generates pulmonary emphysema in senescence marker protein-30 knockout mice.
Am J Physiol Lung Cell Mol Physiol. 2010; 298: L784-L792.
75Kunogi M, Kurihara M, Shigihara T, Ikegami, Kobayashi T, Shindo N, Kumasaka T, Gunji Y, Kikkawa M, Iwakami S, Hino O, Takahashi K, Seyama K.
Clinical and genetic spectrum of Birt-Hogg-Dubé syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature.
J. Med. Genet. 2010; 47:281-287.
76Malinowska-Kolodziej I, Finlay G, Campbell G, Garcia-Moliner ML, Weinstein B, Doughty CA, Qin W, Butterfield C, Short S, Seyama K, Kwiatkowski DJ.
Lymphangioleiomyomatosis: cause of a malignant chylous pleural effusion.
J Clin Oncol. 2010; 28: 4-6.
77Nurok M, Eslick I, Carvalho CR, Costabel U, D'Armiento J, Glanville AR, Harari S, Henske EP, Inoue Y, Johnson SR, Lacronique J, Lazor R, Moss J, Ruoss SJ, Ryu JH, Seyama K, Watz H, Xu KF, Hohmann EL, Moss F.
The International LAM Registry: a component of an innovative web-based clinician, researcher, and patient-driven rare disease research platform.
Lymphat Res Biol. 2010; 8: 81-87.
78Ono A, Naito T, Murakami H, Takahashi T, Nakamura Y, Tsuya A, Kaira K, Igawa S, Shukuya T, Tamiya A, Kaira R, Endo M, Yamamoto N.
Evaluation of S-1 as third- or further-line chemotherapy in advanced non-small-cell lung cancer.
Int J Clin Oncol. 2010; 15: 161-165.
79Sato T, Liu X, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Sun J, Michalski J, Patil A, Basma H, Holz O, Magnussen.
Reduced miR-146a increases prostaglandin E2 in chronic obstructive pulmonary disease fibroblasts.
Am J Respir Crit Care Med. 2010; 182:1020-1029.
80Seyama K, Kumasaka T, Kurihara M, Mitani K, Sato T.
Lymphangioleiomyomatosis: a disease involving the lymphatic system.
Lymphat Res Biol. 2010; 8: 21-31.
81Seyama K, Mitani K, Kumasaka T, Gupta SK, Oommen S, Liu G, Ryu JH, Vlahakis NE.
Lymphangioleiomyoma cells and lymphatic endothelial cells: expression of VEGFR-3 in lymphangioleiomyoma cell clusters.
Am J Pathol. 2010; 176: 2051-2052
82Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J.
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations.
Cell. 2010; 141(1):69-80.
83Shukuya T, Takahashi T, Tamiya A, Ono A, Igawa S, Nakamura Y, Tsuya A, Murakami H, Endo M, Ohde Y, Nakagawa K, Okumura T, Kondo H, Yamamoto N.
Actual status of adjuvant chemotherapy for non-small-cell lung cancer at one Japanese cancer center: the need for increased cooperation between medical oncologists and surgeons.
Med Oncol. 2010; 27: 932-937.
84Shukuya T, Yasui H, Boku N, Onozawa Y, Fukutomi A, Yamazaki K, Taku K, Kojima T, Machida N.
Weekly Paclitaxel After Failure of Gemcitabine in Pancreatic Cancer Patients with Malignant Ascites: A Retrospective Study.
Jpn J Clin Oncol. 2010; 40(12): 1135-8.
85Shukuya T, Ishiwata T, Hara M, Muraki K, Shibayama R, Koyama R, Takahashi K.
Carboplatin plus weekly paclitaxel treatment in non-small-cell lung cancer patients with interstitial lung disease.
Anticancer Res. 2010; 30(10): 4357-61.
86Tajima K, Ohashi R, Sekido Y, Hida T, Nara T, Hashimoto M, Iwakami S, Minakata K, Yae T, Takahashi F, Saya H, Takahashi K.
Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells.
Oncogene. 2010; 29(13):1941-1951.
87Takagi Y, Sato T, Morio Y, Kumasaka T, Mitani K, Miyamoto H, Iwakami S, Kodama Y, Onuma E, Seyama K, Takahashi K.
A pleuro-peritoneal communication through the diaphragm affected with lymphangioleiomyomatosis.
Intern Med. 2010; 49:439-445.
88Takahashi E, Nagano O, Ishimoto T, Yae T, Suzuki Y, Shinoda T, Nakamura S, Niwa S, Ikeda S, Koga H, Tanihara H, Saya H.
Tumor necrosis factor-alpha regulates transforming growth factor-beta-dependent epithelial-mesenchymal transition by promoting hyaluronan-CD44-moesin interaction.
J Biol Chem. 2010; 285(6):4060-73.
89Takahashi K, Yoshimi K.
Clinical characteristics of patients with lung cancer associated with pneumonial.
Nihon Ronen Igakukai Zasshi. 2010; 47(6):550-553.
90Tanai C, Yamamoto N, Ohe Y, Takahashi T, Kunitoh H, Murakami H, Yamamoto N, Nakamura Y, Nokihara H, Shukuya T, Baldwin JR, Koshiji M, Tamura T.
A phase I study of enzastaurin combined with pemetrexed in advanced non-small cell lung cancer.
J Thorac Oncol. 2010; 5: 1068-74.
91Toba M, Nagaoka T, Morio Y, Sato K, Uchida K, Homma N, Takahashi K.
Involvement of Rho kinase in the pathogenesis of acute pulmonary embolism-induced polystyrene microspheres in rats.
Am J Physiol Lung Cell Mol Physiol. 2010; 298(3): L297-L303.
92Togo S, Sugiura H, Nelson A, Kobayashi T, Wang X, Kamio K, Kawasaki S, Bitterman P, Rennard SI, Liu X.
Hepatic growth factor(HGF) inhibits cigarette smoke extract induced apoptosis in human bronchial epithelial cells.
Exp Cell Res. 2010; 316(20): 3501-3511.
93Wadsworth SJ, Atsuta R, McIntyre JO, Hackett TL, Singhera GK, Dorscheid DR.
IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7-mediated Fas ligand cleavage from bronchial epithelial cells.
J Allergy Clin Immunol. 2010; 126(2): 366-374.
94Yanagawa M, Tomiyama N, Honda O, Kikuyama A, Sumikawa H, Inoue A, Tobino K, Koyama M, Kudo M.
Multidetector CT of the lung: Image quality with garnet-based detectors.
Radiology. 2010; 255(3): 944-954.
95Zhang S, Togo S, Minakata K, Gu T, Ohashi R, Tajima K, Murakami A, Iwakami S, Zhang J, Xie C, Takahashi K.
Distinct roles of cholinergic receptors in small cell lung cancer cells.
Anticancer Research. 2010; 30:97-106.
96Syu A, Ishiguro H, Inada T, Horiuchi Y, Tanaka S, Ishikawa M, Arai M, Itokawa M, Niizato K, Iritani S, Ozaki N, Takahashi M, Kakita A, Takahashi H, Nawa H, Keino-Masu K, Arikawa-Hirasawa E, Arinami T.
Association of the HSPG2 gene with neuroleptic-induced tardive dyskinesia Neuropsychopharmacolog.
Apr;35:1155-64. 2010 . IF: 7.048
97Sakamoto Y, Ishijima M, Kaneko H, Kurebayashi N, Ichikawa N, Futami I, Kurosawa H, Arikawa-Hirasawa E
Distinct Mechanosensitive Ca2+ Influx Mechanisms in Human Primary Synovial Fibroblasts
J Orthop Res. 28:859-864, 2010 IF: 2.986
98Namba T, Yabe T, Gonda Y, Ichikawa N, Sanagi T, Arikawa-Hirasawa E, Mochizuki H, Kohsaka S, Uchino S.
Pigment epithelium-derived factor up-regulation induced by memantine, an N-methyl-d-aspartate receptor antagonist, is involved in increased proliferation of hippocampal progenitor cells.
Neuroscience. 2010 May 5;167 :372-83. 2010 IF: 3.357
99Xu Z, Ichikawa N, Kosaki K, Yamada Y, Sasaki T, Sakai LY Kurosawa H, Hattori N, Arikawa-Hirasawa E.
Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition
Matrix Biol. 2010 Jul;29:461-70 IF: 5.074
100Sasaki T, Takagi J, Giudici C, Yamada Y, Arikawa-Hirasawa E, Deutzmann R, Timpl R, Sonnenberg A, Bächinger HP, Tonge D.
Laminin-121-Recombinant expression and interactions with integrins.
Matrix Biol. 2010 Jul;29:484-93. IF: 5.074
101Aihara K, Miyauchi K, Kasai T, Kubota N, Kajimoto K, Tamura H, Kojima T, Yokoyama K, Kurata T, Amano A, Daida H.
Long-term efficacy of pravastatin therapy in diabetic patients undergoing complete coronary revascularization.
J Atheroscler Thromb 2010 Feb 13.
102Kurabayashi M, Sakuma I, Kawamori R, Daida H, Yamazaki T, Yoshida M, Hata M, Masuda I, Kaku K, Yokoi H, Kishimoto J, Nohara R.
Can intensive lipid-lowering therapy with statins ameliorate atherosclerosis in japanese patients?
J Atheroscler Thromb 2010 Mar 9.
103Onishi T, Shimada K, Sato H, Seki E, Watanabe Y, Sunayama S, Ohmura H, Masaki Y, Nishitani M, Fukao K, Kume A, Sumide T, Mokuno H, Naito H, Kawai S, Daida H.
Effects of phase III cardiac rehabilitation on mortality and cardiovascular events in elderly patients with stable coronary artery disease.
Circ J 2010 Mar 6.
104Yanagisawa N, Shimada K, Miyazaki T, Kume A, Kitamura Y, Ichikawa R, Ohmura H, Kiyanagi T, Hiki M, Fukao K, Sumiyoshi K, Hirose K, Matsumori R, Takizawa H, Fujii K, Mokuno H, Inoue N, Daida H.
Polyunsaturated fatty acid levels of serum and red blood cells in apparently healthy Japanese subjects living in an urban area.
J Atheroscler Thromb 2010 Mar 13.
105Miura Y, Fukumoto Y, Shiba N, Miura T, Shimada K, Iwama Y, Takagi A, Matsusaka H, Tsutsumi T, Yamada A, Kinugawa S, Asakura M, Okamatsu S, Tsutsui H, Daida H, Matsuzaki M, Tomoike H, Shimokawa H.
Prevalence and Clinical Implication of Metabolic Syndrome in Chronic Heart Failure – Report From MetS-CHF Study –
Circ J. 74:2612-2621;2010.
106Fukao K, Shimada K, Naito H, Sumiyoshi K, Inoue N, Iesaki T, Kume A, Kiyanagi T, Hiki M, Hirose K, Matsumori R, Ohsaka H, Takahashi Y, Toyoda S, Itoh S, Miyazaki T, Tada N, Daida H.
Voluntary Exercise Ameliorates the Progression of Atherosclerotic Lesion Formation via Anti-inflammatory Effects in Apolipoprotein E-Deficient Mice.
J Atheroscler Tromb. 17:1226-1236;2010
107Miyazaki T, Shimada K, Miyauchi K, Kume A, Tanimoto K, Kiyanagi T, Sumiyoshi S, Hiki M, Mokuno H, Okazaki S, Sato H, Kurata T, Daida H.
Effects of fenofibrate on lipid profiles, cholesterol ester transfer activity, and in-stent intimal hyperplasia in patients after elective coronary stenting.
Lipids Health Dis. 9:122;2010.
108Hiki M, Shimada K, Kiyanagi T, Fukao K, Hirose K, Ohsaka H, Fukushima Y, Kume A, Matsumori R, Sumiyoshi K, Miyazaki T, Ohmura H, Kurata T, Miida T, Daida H.
Single administration of α-glucosidase inhibitors on endothelial function and incretin secretion in diabetic patients with coronary artery disease -Effects of miglitol on endothelial vascular reactivity in type 2 diabetic patients with coronary heart disease in Juntendo University (J-MACH) -.
Circ J. 74:1471-1478;2010.
109Yanagisawa N, Shimada K, Miyazaki T, Kume A, Kitamura Y, Ichikawa R, Ohmura H, Kiyanagi T, Hiki M, Fukao K, Sumiyoshi K, Hirose K, Matsumori R, Takizawa H, Fujii K, Mokuno H, Inoue N, Daida H.
Polyunsaturated fatty acid levels of serum and red blood cells in apparently healthy Japanese subjects living in an urban area.
J Atheroscler Tromb. 17:285-294;2010.
110Onishi T, Shimada K, Sato H, Seki E, Watanabe Y, Sunayama S, Ohmura H, Masaki Y, Nishitani M, Fukao K, Kume A, Sumide T, Mokuno H, Naito H, Kawai S, Daida H.
Effects of phase III cardiac rehabilitation on mortality and cardiovascular events in elderly patients with stable coronary artery disease.
Circ J. 74:709-714;2010.
111Yamasaki Y, Katakami N, Furukado S, Kitagawa K, Nagatsuka K, Kashiwagi A, Daida H, Kawamori R, Kaku K.
Long-term effects of pioglitazone on carotid atherosclerosis in Japanese patients with type 2 diabetes without a recent history of macrovascular morbidity.
J Atheroscler Thromb. 17:1132-40;2010.
112Ohashi T, Shibata R, Morimoto T, Kanashiro M, Ishii H, Ichimiya S, Hiro T, Miyauchi K, Nakagawa Y, Yamagishi M, Ozaki Y, Kimura T, Daida H, Murohara T, Matsuzaki M.
Correlation between circulating adiponectin levels and coronary plaque regression during aggressive lipid-lowering therapy in patients with acute coronary syndrome: subgroup analysis of JAPAN-ACS study.
Atherosclerosis. 212:237-42;2010.
113Arai H, Hiro T, Kimura T, Morimoto T, Miyauchi K, Nakagawa Y, Yamagishi M, Ozaki Y, Kimura K, Saito S, Yamaguchi T, Daida H, Matsuzaki M; JAPAN-ACS Investigators.
More intensive lipid lowering is associated with regression of coronary atherosclerosis in diabetic patients with acute coronary syndrome--sub-analysis of JAPAN-ACS study.
J Atheroscler Thromb. 17:1096-107;2010.
114Kubota N, Miyauchi K, Kasai T, Iesaki T, Kajimoto K, Sumiyoshi K, Dohi T, Daida H.
Synergistic effects of calcium-channel and angiotensin-receptor blockers on endothelial function and inflammatory responses in a porcine drug-eluting stent model.
Circ J. 74:1704-10;2010.
115Hiro T, Kimura T, Morimoto T, Miyauchi K, Nakagawa Y, Yamagishi M, Ozaki Y, Kimura K, Saito S, Yamaguchi T, Daida H, Matsuzaki M; JAPAN-ACS Investigators.
Diabetes mellitus is a major negative determinant of coronary plaque regression during statin therapy in patients with acute coronary syndrome--serial intravascular ultrasound observations from the Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome Trial (the JAPAN-ACS Trial).
Circ J. 74:1165-74;2010.
116Yamagami S, Miyauchi K, Daida H.
Impact of initial degree of coronary narrowing on left ventricular function in first myocardial infarction.
Int Heart J. 51:82-5;2010.
117Miyazaki S, Kasai T, Miyauchi K, Miyazaki T, Akimoto Y, Takagi A, Aihara K, Kawamura M, Suwa S, Kojima S, Sumiyoshi M, Daida H.
Changes of matrix metalloproteinase-9 level is associated with left ventricular remodeling following acute myocardial infarction among patients treated with trandolapril, valsartan or both.
Circ J. 74:1158-64;2010.
118Takagi A, Iwama Y, Yamada A, Aihara K, Daida H.
Estimated glomerular filtration rate is an independent predictor for mortality of patients with acute heart failure.
J Cardiol. 55:317-21;2010.
119Nishimura N, Reien Y, Matsumoto A, Ogura T, Miyata Y, Suzuki K, Nakazato Y, Daida H, Nakaya H.
Effects of nicorandil on the cAMP-dependent Cl- current in guinea-pig ventricular cells.
J Pharmacol Sci. 112:415-23;2010.
120Miyazaki T, Daida H.
Clinical significance of mild lipid-lowering by statins for prevention of cardiovascular disease in Japanese high-risk patients.
Circ J. 74:630-1;2010.
121Kurabayashi M, Sakuma I, Kawamori R, Daida H, Yamazaki T, Yoshida M, Hata M, Masuda I, Kaku K, Yokoi H, Kishimoto J, Nohara R.
Can intensive lipid-lowering therapy with statins ameliorate atherosclerosis in Japanese patients? Rationale and design of the JART study.
J Atheroscler Thromb. 17:416-22;2010.
122Aihara K, Miyauchi K, Kasai T, Kubota N, Kajimoto K, Tamura H, Kojima T, Yokoyama K, Kurata T, Amano A, Daida H.
Long-term efficacy of pravastatin therapy in diabetic patients undergoing complete coronary revascularization.
J Atheroscler Thromb. 17:350-5;2010.
123Dohi T, Miyauchi K, Okazaki S, Yokoyama T, Yanagisawa N, Tamura H, Kojima T, Yokoyama K, Kurata T, Daida H.
Early intensive statin treatment for six months improves long-term clinical outcomes in patients with acute coronary syndrome (Extended-ESTABLISH trial): a follow-up study.
Atherosclerosis. 210:497-502;2010.

英文原著(2009年)

1Nakajima M, Bando K, Miyajima M, Arai H:
Lumboperitoneal shunt placement using computed tomography and fluoroscopy in conscious patients.
J Neurosurg. 2009 Sep;111(3):618-22.
2Komuro Y, Hashizume K, Koizumi T, Miyajima M, Nakanishi H, Arai H:
Cranial expansion with distraction osteogenesis for multiple-suture synostosis in school-aged children.
J Craniofac Surg. 2009 Mar;20(2):457-60.
3Shimoji K, Miyajima M, Karagiozov K, Yatomi K, Matsushima T, Arai H:
Surgical considerations in fourth ventricular ependymoma with the transcerebellomedullary fissure approach in focus.
Childs Nerv Syst. 2009 Oct;25(10):1221-8.
4Kita Y, Baba H, Maeshima H, Nakano Y, Suzuki T, Arai H.
Serum amyloid b protein in young and elderly depression: a pilot study.
Psychogeriatrics. 2009:Dec;9(4):180-5.
5Nakano T, Yamamoto Y, Kitajo K, Takahashi T, Kitazawa S.
Synchronization of spontaneous eye blinks while viewing video stories.
Proc. R. Soc. Lond. B 276: 3635-44, 2009.
6Sasaki, R. & Uka, T.
Dynamic readout of behaviorally relevant signals from area MT during task switching.
Neuron 62: 147-157, 2009.
7Natori, S., Yoshimi, K., Takahashi, T., Kagohashi, M, Oyama, G., Shimo, Y., Hattori, N, Kitazawa, S.
Subsecond reward-related dopamine release in the mouse dorsal striatum.
Neurosci Res 63: 267-272, 2009.
8Ono, F., & Kitazawa, S.
The effect of marker size on the perception of an empty interval.
Psychonomic Bulletin & Review 16: 182-189, 2009.
9Arimura T, Hayashi YK, Murakami T, Oya Y, Funabe S, Arikawa-Hirasawa E, Hattori N, Nishino I, Kimura A. 
Mutational analysis of Fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy 
Circulation Journal  2009 Jan;73(1):158-61
10Fukae J, Sato S, Shiba K, Sato K, Mori H, Sharp PA, Mizuno Y, Hattori N.
Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease.
FEBS Lett. 2009; 583: 521-5.
11Ichikawa N, Iwabuchi K, Kurihara H, Ishii K, Kobayashi T, Sasaki T, Hattori N, Mizuno Y, Hozumi K, Yamada Y, Arikawa-Hirasawa E.
Binding of laminin-1 to GM1 ganglioside in lipid rafts is critical for neurite outgrowth.
J Cell Sci. 2009 Jan 15;122:289-99
12Kanai K, Asahina M, Arai K, Tomiyama H, Kuwabara Y, Uchiyama T, Sekiguchi Y, Funayama M, Kuwabara S, Hattori N, Hattori T.
Preserved cardiac 123I-MIBG uptake and lack of severe autonomic dysfunction in a PARK9 patient.
Mov Disord 2009;24:1403-4.
13Tomiyama H, Li Y, Yoshino H, Mizuno Y, Kubo S, Toda T, Hattori N.
Mutation analysis for DJ-1 in sporadic and familial parkinsonism: Screening strategy in parkinsonism.
Neurosci Lett 2009;455:159-61.
14Yoritaka A, Ohizumi H, Tanaka S, Hattori N.
Parkinson's Disease with and without REM Sleep Behaviour Disorder: Are There Any Clinical Differences?
Eur Neurol. 2009 61:164-170.
15Liu M, Eguchi N, Yamasaki Y, Urade Y, Hattori N, Urabe T.
Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice.
Neuroscience. 2009 Sep 29;163 (1):296-307
16Miyamoto N, Tanaka R, Zhang N, Shimura H, Onodera M, Mochizuki H, Hattori N, Urabe T.
Crucial role for Ser133-phosphorylated form of cyclic AMP-responsive element binding protein signaling in the differentiation and survival of neural progenitors under chronic cerebral hypoperfusion. 
Neuroscience. 2009 Aug 18;162(2):525-36.
17Ogaki K, Fukae J, Noda K, Fujishima K, Hattori N, Okuma Y.
Blurred vision with acute hypertension indicating hypertensive brainstem encephalopathy-case report-.
Neurol Med Chir (Tokyo). 2009; 49 :625-30.
18Saiki S, Ueno Y, Moritani T, Sato T, Sekine T, Kawajiri S, Adachi S, Yokoyama K, Tomizawa Y, Motoi Y, Hattori N.
Extensive hemispheric lesions with radiological evidence of blood-brain barrier integrity in a patient with neuromyelitis optica.
J Neurol Sci. 2009; 284: 217-219.
19Urabe T, Watada H, Okuma Y, Tanaka R, Ueno Y, Miyamoto N, Tanaka Y, Hattori N, Kawamori R.
Prevalence of abnormal glucose metabolism and insulin resistance among subtypes of ischemic stroke in Japanese patients.
Stroke 40: 1289-1295, 2009.
20Sasaki K, Shimura H, Itaya M, Tanaka R, Mori H, Mizuno Y, Kosik KS, Tanaka S, Hattori N.
Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains.
FEBS Lett. 2009 Jul 7;583(13):2194-200.
21Ueno Y, Zhang N, Miyamoto N, Tanaka R, Hattori N, Urabe T.
Edaravone attenuates white matter lesions through endothelial protection in a rat chronic hypoperfusion model.
Neuroscience. 2009 Aug 18;162(2):317-27.
22Tomizawa Y, Fukae J, Noda K, Fujishima K, Yokoyama K, Hattori N, Takahashi T, Okuma Y.
Linear medullary pericanal lesion with longitudinal myelitis can be diagnostic of neuromyelitis optica.
Intern Med. 2009;48(3):175-6.
23Hatano T, Kubo S-I, Shimo Y, Nishioka K, and Hattori N.
Unmet Needs of Patients with Parkinson’s Disease: Interview Survey of Patients and Caregivers.
The Journal of International Medical Research. 37: 717-726, 2009
24Miyauchi K, Takaya N, Hirose T, Ikeda F, Kawamori R, Ohishi H, Yoshida K, Yamamoto M, Arai H, Urabe T, Hattori N, Suzuki M, Maehara T, Sase K, Hatsukami TS, Yuan C, Daida H.
Rationale and design of carotid plaque in human for all evaluations with aggressive rosuvastatin therapy (CHALLENGER Trial).
Circ J 73: 111-115, 2009.
25Okuma Y, Kamei S, Morita A, Yoshii F, Yamamoto T, Hashimoto S, Utsumi H, Hatano T, Hattori N, Matsumura M, Takahashi K, Nogawa S, Watanabe Y, Miyamoto T, Miyamoto M, Hirata K.
Fatigue in Japanese patients with Parkinson’s disease: A study using Parkinson fatigue scale.
Mov Disord 24:1977-1983, 2009
26Zhang N, Miyamoto N, Tanaka R, Mochizuki H, Hattori N, Urabe T.
Activation of tyrosine hydroxylase prevents pneumonia in a rat chronic cerebral hypoperfusion model.
Neuroscience 158: 665-672, 2009.
27Hattori N, Wanga M, Taka H, Fujimura T, Yoritaka A, Kubo S, Mochizuki H.
Toxic effects of dopamine metabolism in Parkinson's disease.
Parkinsonism Relat Disord. 2009 Jan;15 Suppl 1:S35-8.
28Nishioka K, Ross OA, Ishii K, Kachergus JM, Ishiwata K, Kitagawa M, Kono S, Obi T, Mizoguchi K, Inoue Y, Imai H, Takanashi M, Mizuno Y, Farrer MJ, Hattori N.
Expanding the clinical phenotype of SNCA duplication carriers.
Mov Disord. 2009 Sep 15;24(12):1811-9.
29Miyamoto N, Tanaka R, Shimosawa T, Yatomi Y, Fujita T, Hattori N, Urabe T.
Protein kinase A-dependent suppression of reactive oxygen species in transient focal ischemia in adrenomedullin-deficient mice.
J Cereb Blood Flow Metab. 2009 Nov;29(11):1769-79.
30Mellick GD, Siebert GA, Funayama M, Buchanan DD, Li Y, Imamichi Y, Yoshino H, Silburna PA, and Hattori N.
Screening PARK genes for mutations in early-onset Parkinson's disease patients from Queensland, Australia.
Parkinsonism & Related Disorders. 15 (2):105-109, 2009.
31Pirkevi C, Lesage S, Condroyer C, Tomiyama H, Hattori N, Ertan S, Brice A, Başak AN.
A LRRK2 G2019S mutation carrier from Turkey shares the Japanese haplotype.
Neurogenetics 2009;10:271-3.
32Yasuda T, Nihira T, Ren YR, Cao XQ, Wada K, Setsuie R, Kabuta T, Wada, K, Hattori N, Mizuno Y, Mochizuki H.
Effects of UCH-L1 on alpha-synuclein over-expression mouse model ofParkinson's disease.
J Neurochem. 2009 ;108:932-44.
33Kamigaichi R, Kubo S, Ishikawa K, Yokoyama K, Ogaki K, Usui C, Hatta K, Arai H, Mochizuki H, Hattori N.
Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report.
Eur J Neurol. 2009 Feb;16(2):e6.
34Miyamoto N, Tanaka R, Zhang N, ShimuraH, Onodera M, Mochizuki H, Hattori N, Urabe T.
Crucial role Ser133-phosphorylated form of cyclic AMP-responseive element binding protein signaling in the differentiation and survival of neural progenitors under chronic cerebral hypoperfusion.
Neuroscince. 2009;162:525-36.
35Yatomi K, Miyamoto N, Komine-Kobayashi M, Liu M, Oishi H, Arai H, Hattori N, Urabe T.
Pathophysiological dual action of adiponectin after transient focal ischemia in mouse brain. 
Brain Res. 2009 Nov 10;1297:169-76
36Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, Kawakami H, Sakoda S, Yamamoto M, Hattori N, Murata M, Nakamura Y, Toda T.
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Nat Genet. 2009 Dec;41(12):1303-7.
37Suzuki K, Miyamoto M, Miyamoto T, Okuma Y, Hattori N, Kamei S, Yoshii F, Utsumi H, Iwasaki Y, Iijima M, Hirata K.
Correlation between depressive symptoms and nocturnal disturbances in Japanese patients with Parkinson’s disease.
Parkinsonism Relat Disord 15:15-19, 2009
38Cui R, Takahashi F, Ohashi R, Yoshioka M, Gu T, Tajima K, Unnouhara T, Iwakami S, Hirama M, Ishiwata T, Iwase A, Takahashi K.
Osteopontin is involved in the formation of malignant pleunal effusion in lung cancer.
Lung Cancer. 2009; 63(3):368-374.
39Gu T, Ohashi R, Cui R, Tajima K, Yoshioka M, Iwakami S, Sasaki S, Shinohara A, Matsukawa T, Kobayashi J, Inaba Y, Takahashi K.
Osteopontin is involved in the development of acquired chemo-resistance of cisplatin in small cell lung cancer.
Lung Cancer. 2009; 66(2):176-183.
40Harada H, Yamamoto N, Takahashi T, Endo M, Murakami H, Tsuya A, Nakamura Y, Ono A, Igawa S, Shukuya T, Tamiya A, Nishimura T.
Comparison of chemotherapy regimens for concurrent chemoradiotherapy in unresectable stage III non-small cell lung cancer.
Int J Clin Oncol. 2009; 14: 507-12.
41Higa F, Uchihara T, Haranaga S, Yara S, Tateyama M, Oshiro Y, Shiraishi M, Kumasaka T, Seyama K, Fujita J.
Malignant epithelioid angiomyolipoma in the kidney and liver of a patient with pulmonary lymphangioleiomyomatosis: lack of response to sirolimus.
Intern Med. 2009; 48: 1821-1825.
42Ichinose M, Seyama K, Nishimura M, Fukuchi Y, Nagai A, Mishima M, Kubo K.
Beta-2 agonist research and evaluation committee in COPD(BAREC) study group. Additive effects of transdermal tulobuterol to inhaled tiotropium in patients with COPD.
Respiratory Medicine. 2009; 1-8.
43Ito J, Sekiya M, Miura K, Yoshimi K, Suzuki T, Seyama K, Izumi H, Uekusa T, Takahashi K.
Refractory recurrent thymoma successfully treated with long-acting somatostatin analogue and prednisolone.
Internal Medicine. 2009; 48: 1061-1064.
44Iwakami S, Sato T, Takagi H, Fujii M, Iwakami N, Yoshimi K, Koyama R, Ichikawa M, Yoshioka M, Takahashi K.
An autopsy case of subacute cor pulmonale due to pulmonary tumor cell emboli in a patient with gastric cancer.
Internal Medicine. 2009; 48: 1057-1060.
45Kamijo S, Takai T, Kuhara T, Tokura T, Ushio H, Ota M, Harada N, Ogawa H, Okumura K.
Cupressaceae pollen grains modulate dendritic cell response and exhibit IgE-inducingadjuvant activity in vivo.
J Immunol. 2009; 183:6087-6094.
46Liu X, Nelson A, Wang X, Kanaji N, Kim M, Sato T, Nakanishi M, Li Y, Sun J, Michalski J, Patil A, Basma H, Rennard SI.
MicroRNA-146a modulates human bronchial epithelial cell survival in response to the cytokine-induced apoptosis.
Biochemical and Biophysical Research Communications. 2009; 380: 177-182.
47Mitani K, Kumasaka T, Takemura H, Hayashi T, Gunji Y, Kunogi M, Akiyoshi T, Takahashi K, Suda K, Seyama K.
Cytologic, immunocytochemical and ultrastructural characterization of lymphangioleiomyomatosis cell clusters in chylous effusion of patients with lymphangioleiomyomatosis.
Acta Cytologica 2009; 53(4):402-409.
48Odajima N, Betsuyaku T, Nasuhara Y, Inoue H, Seyama K, Nishimura M.
Matrix metalloproteinases in blood from patients with LAM.
Respir Med. 2009; 103(1): 124-129.
49Ohashi R, Tajima K, Takahashi F, Cui R, Gu T, Shimizu K, Nishio K, Fukuoka K, Nakano T, Takahashi K.
Osteopontin modulates malignant pleural mesothelioma cell functions in vitro.
Anticancer Res. 2009; 29(6):2205-2214.
50Sekiya M, Ishiwata T, Yoshimi K, Nagaoka T, Morio Y, Shiota S, Suzuki T, Seyama K, Takahashi K.
Malignant pleurisy associated with primary lung cancer well controlled by pleurodesis using distilled water.
Internal Medicine. 2009; 48: 1051-1055.
51Shukuya T, Takahashi T, Tamiya A, Ono A, Igawa S, Tsuya A, Nakamura Y, Murakami H, Naito T, Kaira K, Endo M, Yamamoto N.
Evaluation of the safety and compliance of 3-week cycles of vinorelbine on days 1 and 8 and cisplatin on day 1 as adjuvant chemotherapy in Japanese patients with completely resected pathological stage IB to IIIA non-small cell lung cancer: A retrospective study.
Jpn. J. Clin. Oncol. 2009; 39: 158-162.
52Shukuya T, Takahashi T, Tamiya A, Ono A, Igawa S, Nakamura Y, Tsuya A, Murakami H, Naito T, Kaira K, Endo M, Yamamoto N.
Gefitinib plus paclitaxel after failure of gefitinib in non-small cell lung cancer initially responding to gefitinib.
Anticancer Res. 2009; 29: 2747-2751.
53Su MC, Chiu KL, Ruttanaumpawan P, Shiota S, Yumino D, Redolfi S, Haight JS, Yau B, Lam J, Bradley TD.
Difference in upper airway collapsibility during wakefulness between men and women in response to lower-body positive pressure.
Clin Sci (Lond). 2009 May;116(9):713-20.
54Sugiura H, Ichikawa T, Liu X, Kobayashi T, Wang XQ, Kawasaki S, Togo S, Kamio K, Mao L, Ann Y, Ichinose M, Rennard SI.
N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts.
Pulm Pharmacol Ther. 2009; 22(6): 487-91.
55Takahashi F, Kumasaka T, Nagaoka T, Wakiya M, Fujii H, Shimizu K, Uchida K, Morio Y, Seyama K, Hino O, Takahashi K, Fukuchi Y.
Osteopontin expression in pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma.
Pathol Int. 2009; 59(10):752-756.
56Tamiya A, Endo M, Shukuya T, Igawa S, Tsuya A, Nakamura Y, Murakami H, Takahashi T, Boku N, Yamamoto N.
Features of gemcitabine-related severe pulmonary toxicity: patients with pancreatic or biliary tract cancer.
Pancreas. 2009; 38: 838-840.
57Togo S, Liu X, Wang X, Sugiura H, Kamio K, Kawasaki S, Kobayashi T, Ertl RF, Ahn Y, Holz O, Magnussen H, Fredriksson K, Skold CM, Rennard SI.
The PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1 stimulated fibroblasts.
Am J Physiol Lung Cell Mol Physiol. 2009; 296(6):L959-69.
58Yoshioka M, Sagara H, Takahashi F, Harada N, Nishio K, Mori A, Ushio H, Shimizu K, Okada T, Ota M, Ito Y, Nagashima O, Atsuta R, Suzuki T, Fukuda T, Fukuchi Y, Takahashi K.
Role of multidrug resistance-associated protein 1 in the pathogenesis of allergic airway inflammation.
Am J Physiol Lung Cell Mol Physiol. 2009; 296(1): L30-L36.
59Arimura T, Hayashi YK, Murakami T, Oya Y, Funabe S, Arikawa-Hirasawa E, Hattori N, Nishino I and Kimura A.
Mutational analysis of Fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy
Circulation Journal Jan;73(1):158-61, 2009 IF: 3.940
60Ichikawa N, Iwabuchi K, Kurihara H, Ishii K, Kobayashi ,Sasaki T, Hattori N,Mizuno Y, Hozumi K, Yamada Y, and Arikawa-Hirasawa E.
Binding of laminin-1 to GM1 ganglioside in lipid rafts is critical forneurite outgrowth.
J Cell Sci. Jan 15;122:289-99, 2009 IF: 5.432
61Azuma K, Ichimura K, Mita T, Nakayama S, Jin WL, Hirose T, Fujitani Y, Sumiyoshi K, Shimada K, Daida H, Sakai T, Mitsumata M, Kawamori R, Watada H.
Presence of alpha-smooth muscle actin-positive endothelial cells in the luminal surface of adult aorta.
Biochem Biophys Res Commun. 380:620-6;2009.
62Dohi T, Miyauchi K, Kasai T, Kajimoto K, Kubota N, Tamura H, Yokoyama T, Kojima T, Yokoyama K, Kurata T, Daida H.
Impact of metabolic syndrome on 10-year clinical outcomes among patients with acute coronary syndrome.
Circ J. 73:1454-8;2009.
63Dohi T, Miyauchi K, Okazaki S, Yokoyama T, Yanagisawa N, Tamura H, Kojima T, Yokoyama K, Kurata T, Daida H.
Early intensive statin treatment for six months improves long-term clinical outcomes in patients with acute coronary syndrome (extended-ESTABLISH trial): A follow-up study.
Atherosclerosis 2009 Dec 4.
64Hiki M, Shimada K, Ohmura H, Kiyanagi T, Kume A, Sumiyoshi K, Fukao K, Inoue N, Mokuno H, Miyazaki T, Daida H.
Serum levels of remnant lipoprotein cholesterol and oxidized low-density lipoprotein in patients with coronary artery disease.
J Cardiol. 53:108-16; 2009.
65Hiro T, Kimura T, Morimoto T, Miyauchi K, Nakagawa Y, Yamagishi M, Ozaki Y, Kimura K, Saito S, Yamaguchi T, Daida H, Matsuzaki M, JAPAN-ACS Investigators.
Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome: A multicenter randomized trial evaluated by volumetric intravascular ultrasound using pitavastatin versus atorvastatin (JAPAN-ACS [japan assessment of pitavastatin and atorvastatin in acute coronary syndrome] study).
J Am Coll Cardiol. 54:293-302; 2009.
66Kajimoto K, Miyauchi K, Kasai T, Shimada K, Kojima Y, Shimada A, Niinami H, Amano A, Daida H.
Short-term 20-mg atorvastatin therapy reduces key inflammatory factors including c-jun N-terminal kinase and dendritic cells and matrix metalloproteinase expression in human abdominal aortic aneurysmal wall.
Atherosclerosis. 206:505-11; 2009.
67Kajimoto K, Miyauchi K, Kasai T, Yanagisawa N, Yamamoto T, Kikuchi K, Nakatomi T, Iwamura H, Daida H, Amano A.
Metabolic syndrome is an independent risk factor for stroke and acute renal failure after coronary artery bypass grafting.
J Thorac Cardiovasc Surg. 137:658-63; 2009.
68Kaku K, Daida H, Kashiwagi A, Yamashina A, Yamazaki T, Momomura S, Iwase T, Yamasaki Y, Nagatsuka K, Kitagawa K, Kawamori R.
Long-term effects of pioglitazone in japanese patients with type 2 diabetes without a recent history of macrovascular morbidity.
Curr Med Res Opin. 25:2925-32; 2009.
69Kasai T, Miyauchi K, Kajimoto K, Kubota N, Dohi T, Kurata T, Amano A, Daida H.
The adverse prognostic significance of the metabolic syndrome with and without hypertension in patients who underwent complete coronary revascularization.
J Hypertens. 27:1017-24; 2009.
70Kasai T, Miyauchi K, Kajimoto K, Kubota N, Kurata T, Amano A, Daida H.
The impact of pravastatin therapy on long-term outcome in patients with metabolic syndrome undergoing complete coronary revascularization.
Circ J. 73:2104-9; 2009.
71Kasai T, Miyauchi K, Kajimoto K, Kubota N, Yanagisawa N, Amano A, Daida H.
Relationship between the metabolic syndrome and the incidence of stroke after complete coronary revascularization over a 10-year follow-up period.
Atherosclerosis. 207:195-9; 2009.
72Matsunaga E, Takaya N, Yokoyama T, Akimoto Y, Miyauchi K, Daida H.
Relationship between coronary artery wall thickness measured by 64-slice multidetector computed tomography and cardiovascular risk factors.
Circ J. 73:681-5; 2009.
73Miyauchi K, Kojima T, Yokoyama T, Kurata T, Yokoyama K, Kawamura M, Suwa S, Okazaki S, Inoue K, Fujiwara Y, Sumiyoshi M, Tanimoto K, Nakazato Y, Yamagami S, Daida H.
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in juntendo university (ALPS-J).
Cardiovasc Drugs Ther. ;23:409-13; 2009.
74Miyauchi K, Takaya N, Hirose T, Ikeda F, Kawamori R, Ohishi H, Yoshida K, Yamamoto M, Arai H, Urabe T, Hattori N, Suzuki M, Maehara T, Sase K, Hatsukami TS, Yuan C, Daida H.
Rationale and design of the carotid plaque in human for all evaluations with aggressive rosuvastatin therapy (CHALLENGER trial): Evaluation by magnetic resonance imaging.
Circ J. 73:111-5; 2009.
75Nishizawa H, Suzuki T, Shioya T, Nakazato Y, Daida H, Kurebayashi N.
Causes of abnormal Ca2+ transients in guinea pig pathophysiological ventricular muscle revealed by Ca2+ and action potential imaging at cellular level.
PLoS One. 4:e7069; 2009.
76Onishi T, Shimada K, Sunayama S, Ohmura H, Sumide T, Masaki Y, Fukao K, Nishitani M, Kume A, Sato H, Naito H, Kawai S, Amano A, Daida H.
Effects of cardiac rehabilitation in patients with metabolic syndrome after coronary artery bypass grafting.
J Cardiol. 53:381-7; 2009.
77Shi J, Iesaki T, Kubota N, Sumiyoshi K, Kajimoto K, Kikuchi K, Daida H, Amano A.
Skeletonization with an ultrasonic scalpel is as safe as a non-skeletonized dissection in preserving the endothelial function of the human gastroepiploic artery.
Interact Cardiovasc Thorac Surg. 8:216-20; 2009.
78Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T.
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
J Biol Chem. 284:29109-24; 2009.
79Sumide T, Shimada K, Ohmura H, Onishi T, Kawakami K, Masaki Y, Fukao K, Nishitani M, Kume A, Sato H, Sunayama S, Kawai S, Shimada A, Yamamoto T, Kikuchi K, Amano A, Daida H.
Relationship between exercise tolerance and muscle strength following cardiac rehabilitation: Comparison of patients after cardiac surgery and patients with myocardial infarction.
J Cardiol. 54:273-81; 2009.
80Takayama T, Hiro T, Yamagishi M, Daida H, Hirayama A, Saito S, Yamaguchi T, Matsuzaki M, COSMOS Investigators.
Effect of rosuvastatin on coronary atheroma in stable coronary artery disease: Multicenter coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in japanese subjects (COSMOS).
Circ J. 73:2110-7; 2009.
81Tanaka Y, Daida H, Imai Y, Miyauchi K, Sato Y, Hiwatari M, Kitagawa A, Kishimoto J, Yamazaki T, Kawamori R.
Morning home blood pressure may be a significant marker of nephropathy in japanese patients with type 2 diabetes: ADVANCED-J study 1.
Hypertens Res. 32:770-4; 2009.
82Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T (2009)
Nesfatin-1-regulated paraventricular oxytocinergic signaling causes anorexia through a leptin-independent melanocortin pathway.
Cell Metabolism 10: 355-365
83Matsuda, T., Kido, Y., Nakano-Hashimoto, N., Kaisho, T., Tanaka, T., Asahara, S., Shigeyama, Y., Takeda, A., Inoue, T., Shibutani, Y., Koyanagi, M., Hosooka, T., Matsumoto, M., Inoue, H., Uchida, T., Koike, M., Uchiyama, Y., Akira, S., Kasuga, M. (2009)
Ablation of C/EBP beta alleviates ER stress and pancreatic beta cell failure through induction of GRP78.
J Clin Invest 120:115-126
84Yagita K, Yamanaka I, Koinuma S, Shigeyoshi Y, Uchiyama Y. (2009)
Mini Screening of Kinase Inhibitors Affecting Period-length of Mammalian Cellular Circadian Clock.
Acta Histochem Cytochem 42:89-93
85Sugita S, Horie S, Nakamura O, Maruyama K, Takase H, Usui Y, Takeuchi M, Ishidoh K, Koike M, Uchiyama Y, Peters C, Yamamoto Y, Mochizuki M. (2009)
Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.
J Immunol 183:5013-5022
86Ohsawa S, Hamada S, Asou H, Kuida K, Uchiyama Y, Yoshida H, Miura M. (2009)
Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb.
J Neurosci 29:11385-11292.
87Shibata M*, Yoshimura K*, Furuya M, Koike M, Ueno T, Komatsu M, Arai H, Tanaka K, Kominami E, Uchiyama Y (2009)
The MAP1-LC3 conjugation system is involved in lipid droplet formation.
Biophys Biochem Res Comm 382: 419-423 (* equally contributed)
88Nada S*, Hondo A*, Kasai A*, Koike M*, Saito K, Uchiyama Y, Okada M (2009)
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
EMBO J 28: 477-489 (* equally contributed)
89Gotoh K, Lu Z, Morita M, Shibata M, Koike M, Waguri S, DonoK, DokiY, Kominami E, Sugioka A, Monden M, Uchiyama Y (2009)
Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation.
Autophagy 5:351-360
90Garcia M, Rao M, Fujimoto J, Garcia V, Shah S, Crum J, Gotow T, Uchiyama Y, Ellisman MH, Calcutt N, Cleveland D (2009)
Phosphorylation of highly conserved NF-M KSP repeats is not required for myelin-dependent radial axonal growth.
J Nurosci 29: 1277-1284
91Miyamoto K, Shiozaki M, Shibata M, Koike M, Uchiyama Y, Gotow T (2009)
Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats.
J Neurosci Res 87: 556-566

英文原著(2008年)

1Iizuka T, Kanzaki S, Mochizuki H, Inoshita A, Narui Y, Furukawa M, Kusunoki T, Saji M, Ogawa K, Ikeda K.
Noninvasive In Vivo Delivery of Transgene via Adeno-Associated Virus into Supporting Cells of the Neonatal Mouse Cochlea.
Hum Gene Ther. 2008 Apr;19(4):384-90.
2Iguchi Y, Kimura K, Kobayashi K, Ueno Y, Shibazaki K, Inoue T.
Microembolic signals at 48 hours after stroke onset contribute to new ischemia within a week.
J Neurol Neurosurg Psychiatry 2008;79;253-259
3Mizuno Y, Hattori N, Kubo S, Sato S, Nishioka K, Hatano T, Tomiyama H, Funayama M, Machida Y, Mochizuki H.
Progress in the Pathogenesis and Genetics of Parkinson’s Disease Philosophical transactions.
Biological sciences 2008 Apr 15
4Ning YP, Kanai K, Tomiyama H, Li Y, Funayama M, Yoshino H, Sato S, Asahina M, Kuwabara S, Takeda A, Hattori T, Mizuno Y, Hattori N.
PARK9-linked parkinsonism in Eastern Asia: Mutation detection in ATP13A2 and clinical phenotype.
Neurology 2008;70;1491-1493
5Obi K, Akiyama H, Kondo H, Shimomura Y, Hasegawa M, Iwatsubo T, Mizuno Y, Mochizuki H.
Relationship of phosphorylated alpha-synuclein and tau accumulation to Abeta deposition in the cerebral cortex of dementia with Lewy bodies.
Exp Neurol. 2008 Apr;210(2):409-20
6Obi k, Nishioka K, Owen A. Ross OA, Terada T, Yamazaki K, Sugiura, A, Takanashi M, Mizoguchi K, Mori H, Mizuno Y, Hattori N.
Clinicopathological study of a SNCA gene duplication patient with Parkinson disease and dementia
Neurology. 2008 Jan 15;70(3):238-41
7Oizumi H, Hayashita-Kinoh H, Hayakawa H, Arai H, Furuya T, Ren YR, Yasuda T, Miura M, Mizuno Y, Mochizuki H
Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson’s disease.
Neurosci Res 60, 15-21, 2008
8Shimizu Y, Yokoyama K, Misu T, Takahashi T, Fujihara K, Kikuchi S, Itoyama Y, Iwata M.
Development of extensive brain lesions following interferon beta therapy in relapsing neuromyelitis optica and longitudinally extensive myelitis.
J Neurol 255:305-307 2008
9Shibazaki K, Iguchi Y, Kimura K, Ueno Y, Inoue T.
New asymptomatic ischemic lesions on diffusion-weighted imaging after cerebral angiography.
J Neurol Sci 266:150-155 2008
10Yamashiro K, Komine-Kobayashi M, Hatano T, Urabe T, Mochizuki H, Hattori N, Iwama Y, Daida H, Sakai M, Nakayama T, Mizuno Y.
The frequency of cardiac valvular regurgitation in Parkinson's disease.
Mov Disord. 2008 Apr 8
11Kagohashi M, Nakazato T, Yoshimi Y, Moizumi S, Hattori N, Kitazawa S.
Wireless voltammetry recording in unanesthetised behaving rats .
Neurosci Res. 2008 Jan;60(1):120-7.
12Ono, F., & Kawahara, J.
The effect of false memory on temporal perception.
Psychol Res 2008:72 61-64
13Gotow T, Shiozaki M, Higashi T, Yoshimura K, Shibata M, Kominami E, Uchiyama Y (2008)
Hepatic gap junctions in the hepatocarcinogen-resistant DRH rat.
Histochem Cell Biol 130: 583-594
14Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N, Ohsugi Y, Nishikawa T, Ripley B, Kimura A, Kishimoto T, Naka T. (2008)
Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.
Arthritis Rheum 58: 3710-3719
15Qiao L, Hamamichi S, Caldwell KA, Caldwell GA, Yacoubian TA, Wilson S, Xie Z-L, Speake LD, Parks R, Crabtree D, Liang Q, Crimmins S, Schneider L, Uchiyama Y, Iwatsubo T, Zhou Y, Peng L, Lu YM, Standaert DG, Walls KC, Shacka JJ, Roth KA, Zhang J (2008)
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.
Mol Brain 1:17
16Sou YS, Waguri S, Iwata JI, Ueno T, Fujimura T, Hara T, Sawada N, Yamada A, Mizushima N, Uchiyama Y, Kominami E, Tanaka K, Komatsu M (2008)
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.
Mol Biol Cell 19: 4762-4775
17Maeda Y, Ide T, Koike M, Uchiyama Y, Kinoshita T (2008)
GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.
Nat Cell Biol 10: 1135-1145
18Mori Y*, Koike M*, Moriishi E, Kawabata A, Tang H, Oyaizu H, Uchiyama Y, Yamanishi K (2008)
Human herpesvirus-6 induces MVB formation and virus egress occurs via an exosomal release pathway. Traffic 9:1728-1742 *equal contributors
19Saito F, Kuwata H, Oiki E, Koike M, Uchiyama Y, Honda K, Takeda K (2008)
Inefficient phagosome maturation in infant macrophages.
Biochem Biophys Res Commun 375: 113-118
20Yoshioka A, Miyata H, Doki Y, Yamasaki M, Sohma I, Gotoh K, Takiguchi S, Fujiwara Y, Uchiyama Y, Monden M (2008)
LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers.
Int J Oncol 33:461-468.
21Oppenheim RW, Blomgren K, Ethell DW, Koike M, Komatsu M, Prevette D, Roth KA, Uchiyama Y, Vinsant S, Zhu C (2008)
Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.
J Neurosci 28: 1490-1497
22Shiozaki M, Yoshimura K, Shibata M, Koike M, Uchiyama Y, Gotow T (2008)
Morphological and biochemical signs of age-related neurodegenerative changes in Klotho mutant mice.
Neuroscience 152:924-941
23Kiyohara Y, Nishii K, Ukai-Tadenuma M, Ueda H, Uchiyama Y, Yagita K (2008)
Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector based strategy.
Nucl Acids Res 36 (4): e23
24Suzuki C, Takabatake Y, Tanaka H, Koike M, Shibata M, Uchiyama Y, Takahara S, Imai E, Isaka Y (2008)
Participation of autophagy in renal ischemia/reperfusion injury.
Biochem Biophys Res Comm 368:100-106
25Fujibayashi A, Taguchi T, Misaki R, Ohtani M, Dohmae N, Takio K, Yamada M, Gu J, Yamakami M, Fukuda M, Waguri S, Uchiyama Y, Yoshimori T, Sekiguchi K (2008)
Human RME-8 is involved in membrane trafficking through early endosomes.
Cell Struct Funct 33:35-50
26Takatsuka A, Yagi R, Koike M, Oneyama C, Nada S, Schmedt C, Uchiyama Y, Okada M (2008)
Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility.
Dev Biol 315:474-488
27Hasegawa S, Hamada S, Kumode Y, Esumi S, Katori S, Fukuda E, Uchiyama Y, Hirabayashi T, Mombaerts P, Yagi T (2008)
The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse.
Mol Cell Neurosci 38:66-79
28Moriyama Y, Sekine C, Koyanagi A, Koyama N, Ogata H, Chiba S, Hirose S, Okumura K, Yagita H
Koike M, Shibata S, Tadakoshi T, Gotoh K, Komatsu M, Waguri S, Kawahara N, Kuida K, Nagata S, Kominami E, Tanaka K, Uchiyama Y (2008)
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury.
Am J Pathol 172: 454-469
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Autophagy 4: 151-175

英文原著(2007年)

1Arai T, Fujishima K, Kobayashi H, Yamamoto T, Mori K, Maeda M, Mizuno Y, Okuma Y.
Pseudoathetosis caused by migrated cervical disc.
Parkinsonism Rel Disord 13:59-61,2007
2Ephraty L, Porat O, Israeli D, Cohen OS, Tunkel O, Yael S, Hatano Y, Hattori N, Hassin-Baer S. 
Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations.
Movement Disorders, Vol. 22, No. 4, 2007
3Fukae J, Noda K, Fujishima K, Wada R, Yoshiike T, Hattori N, Okuma Y.
Successful treatment of relapsing neuro-Sweet's disease with corticosteroid and dapsone combination therapy.
Clin Neurol Neurosurg. 2007 Dec;109(10):910-3.
4Fukae J, Mizuno Y, Hattori N. 
Mitochondrial dysfunction in Parkinson's disease.
Mitochondrion 7:58-62, 2007
5Fujita E, Kouroku Y, Isoai A, Kumagai H, Misutani A, Matsuda C, Hayashi YK, Momoi T.
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).
Hum Mol Genet 2007;16:618-629
6Funayama M, Li Y, Tomiyama H, Yoshino H, Imamichi Y, Yamamoto M, Murata M, Toda T, Mizuno Y, and Hattori N.
Leucine-rich repeat kinase 2 G2385R variant is a risk factor for Parkinson disease in Asian population.
Neuroreport 2007;18(3):273-275.
7Hara K, Momose Y, Tokiguchi S, Shimohata M, Terajima K, Onodera O, Kakita A, Yamada M, Takahashi H, Hirasawa M, Mizuno Y, Ogata K, Goto J, Kanazawa I, Nishizawa M, Tsuji S ;
Multiplex families with multiple system atrophy.
Arch Neurol. 2007 ;64(4):545-51.
8Hatano T, Kubo S, Imai S, Maeda M, Ishikawa K, Mizuno Y, Hattori N.
Leucine-rich repeat kinase 2 associates with lipid rafts.
Hum Mol Genet. 16:678-690, 2007
9Hayakawa H, Hayashita-Kinoh H, Nihira T, Mizuno Y, Mochizuki H,
The isolation of neural stem cells from olfactory bulb of Parkinson's disease model.
Neurosci Res Mar;57(3):393-8:2007
10Ihara M, Yamasaki N, Hagiwara A, Tanigaki A, Kitano A, Hikawa R, Tomimoto H, Noda M, Takanashi M, Mori H, Hattori N, Miyakawa T, Kinoshita M. 
Sept4, a Component of Presynaptic Scaffold and Lewy Bodies, Is Required for the Suppression of alpha-Synuclein Neurotoxicity.
Neuron 2007;53:519-33
11Ishihara L, Gibson RA, Warren L, Amouri R, Lyons K, Wielinski C, Hunter C, Swartz JE, Elango R, Akkari PA, Leppert D, Surh L, Reeves KH, Thomas S, Ragone L, Hattori N, Pahwa R, Jankovic J, Nance M, Freeman A, Gouider-Khouja N, Kefi M, Zouari M, Ben Sassi S, Ben Yahmed S, El Euch-Fayeche G, Middleton L, Burn DJ, Watts RL, Hentati F.
Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families.
Mov Disord. 2007;22:55-61
12Itoh M, Ide S, Takashima S, Kudo S, Nomura Y, Segawa M, Kubota T, Mori H, Tanaka S, Horie H, Tanabe Y, Goto Y. :
Methyl CpG-Binding Protein 2(a Mutation of Which Causes Rett Syndrome) Directly Regulates Insulin-Like Growth Factor Binding Protein 3 in Mouse and Human Brains.
J Neuropathol Exp Neurol vol66, No2,2007,pp117-123
13Iguchi Y, Kimura K, Kobayashi K, Ueno Y, Shibazaki K, Iwanaga T, Inoue T.
In-hospital onset ischemic stroke may be associated with atrial fibrillation and right-to-left shunt.
J Neurol Sci 2007;254:39-43
14Iguchi Y, Kimura K, Inoue T, Wada K, Ueno Y, Sunada Y.
Diffusion-weighted MR images in patient with neuropsychiatric lupus: A case report.
J Clin Neurosci 2007;14:273-275
15Kawajiri S, Tani M, Noda K, Fujishima K, Hattori N, Okuma Y.
Segmental zoster paresis of limbs: Report of three cases and review of literature.
Neurologist 13:313-317,2007
16Kasai S, Urushibata S, Hozumi K, Yokoyama F, Ichikawa N, Kadoya Y, Nishi N, Watanabe N, Yamada Y, Nomizu M.
Identification of multiple amyloidogenic sequences in laminin-1.
Biochemistry. 2007 Apr 3;46(13):3966-74. Epub 2007 Mar 10.
17Kerever A, Schnack J, Vellinga D, Ichikawa N, Moon C, Arikawa-Hirasawa E, Efird JT, Mercier F.
Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor fibroblast growth factor 2 from the extracellular milieu.
Stem Cells. 2007 Sep;25(9):2146-57. Epub 2007 Jun 14.
18Kono S, Shirakawa K, Ouchi Y, Sakamoto M, Ida H, Sugiura T, Tomiyama H, Suzuki H, Takahashi Y, Miyajima H, Hattori N, Mizuno Y.
Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier.
J Neurol Sci. 252:181-184, 2007
19Kumazawa R, Tomiyama H, Li Y, Imamichi Y, Funayama M, Yoshino H, Yokochi F, Fukusako T, Takehisa Y, Kashihara K, Kondo T, Elibol B, Bostantjopoulou S, Toda T, Takahashi H, Yoshii F, Mizuno Y, Hattori N.
Mutation analysis of the PINK1 gene in 395 patients with Parkinson’s disease.
Arch Neurol. In press
20Kawakami T, Kanazawa H, Satoh T, Ieda M, Ieda Y, Kimura K, Mochizuki H, Shimada T, Yokoyama C, Ogawa S, Tanabe T, Fukuda K.
AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.
Biochem Biophys Res Commun. 2007 23;363(3):656-61.
21Kawahara G, Okada M, Morone N, Ibarra CA, Nonaka I, Noguchi S, Hayashi YK, Nishino I.
Reduced cell anchorage may cause sarcolemma-specific collagen VI deficiency in Ullrich disease.
Neurology 2007;69:1043-1049
22Keira Y, Noguchi S, Kurokawa R, Fujita M, Minami N, Hayashi YK, Kato T, Nishino I.
Characterization of lobulated fibers in limb girdle muscular dystrophy type 2A by gene expression profiling.
Neurosci Res 2007;57:513-521
23Kimura K, Ieda M, Kanazawa H, Yagi T, Tsunoda M, Ninomiya S, Kurosawa H, Yoshimi K, Mochizuki H, Yamazaki K, Ogawa S, Fukuda K.
Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy.
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24Lee J, Kagamihara Y, Kakei S.
Development of a quantitative evaluation system for motor control using wrist movement. –An analysis of movement disorders in patients with cerebellar diseases-
Journal of Japanese Society of Laboratory Medicine, 55(10); 912-921, 2007
25Liewluck T, Hayashi YK, Ohsawa M, Kurokawa R, Fujita M, Noguchi S, Nonaka I, Nishino I.
Unfolded protein response and aggresome formation in hereditary reducing-body myopathy.
Muscle Nerve 2007;35:322-326
26Liang W-C, You C-Y, Liu C-Y, Lee C-S, Goto K, Hayashi YK, Jong YJ.
Novel LMNA mutation in a Taiwanese family with autosomal dominant Emery-Dreifuss muscular dystrophy.
J Formos Med Assoc 2007;106:S27-S31
27Lin YC, Murakami T, Hayashi YK, Nishino I, Nonaka I, Yuo CY, Jong YJ.
A novel FKRP gene mutation in a Taiwanese patient with limb-girdle muscular dystrophy 2I.
Brain Dev 2007;29:234-238
28Liu M, Eguchi N, Yamasaki Y, Urade Y, Hattori N, Urabe T:
Focal cerebral ischemia/reperfusion injury in mice induces hematopoietic prostaglandin D synthase in microglia and macrophages.
Neuroscience 145: 520-529, 2007.
29Malicdan MC, Noguchi S, Nonaka I, Hayashi YK, Nishino I.
A Gne knockout mouse expressing human GNE D176V mutation develops features similar to distal myopathy with rimmed vacuoles or hereditary inclusion body myopathy.
Hum Mol Genet 2007;16:2669-2682
30Mellick GD, Siebert GA, Funayama M, Buchanan DD, Li Y, Imamichi Y, Yoshino H, Silburn PA, Hattori N.
Screening PARK Genes for Mutations in Early Onset Parkinson’s Disease Patients from Queensland, Australia.

Parkinsonism & Related Disorders. In press.
31Mizuno Y, Kanazawa I, Kuno S, Yanagisawa N, Yamamoto M, Kondo T,
Japanese Parkinson-Entacapone Study Group. Placebo-controlled, double-blind dose-finding study of entacapone in fluctuating parkinsonian patients.
Mov Disord 2007;22:75-80
32Mori K, Nakao Y, Yamamoto T, Okuma Y, Osada H, Esaki T.
Partial (one-third) side-to-end hypoglossal-facial anastomosis ensures facial reanimation without tongue dysfunction.
Neurosurg Q 17:180-184,2007
33Muchir A, Pavlidis P, Bonne G, Hayashi YK, Worman HJ.
Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery Dreifuss muscular dystrophy.
Hum Mol Genet 2007;16:1884-1895
34Namba T, Mochizuki H, Onodera M, Namiki H, SekiT
Postnatal neurogenesis in hippocampal slicecultures: early in vitro labeling of neuronal precursor cells leads to efficient neuronal production.
J Neurosci Res, 85: 1704-1712, 2007
35Nakashima I, Fukazawa T, Ota K, Nohara C, Warabi Y, Ohashi T, Miyazawa I, Fujihara K, Itoyama Y.
Two subtype of optic-spinal form of multiple sclerosis in Japan: Clinical and laboratory features.
J Neurol. 2007 Apr;254(4) 488-92
36Ohsawa M, Liewluck T, Ogata K, Iizuka T, Hayashi Y, Nonaka I, Sasaki M, Nishino I.
Familial reducing body myopathy.
Brain Dev 2007;29:112-116
37Ohshima T, Hirasawa M, Tabata H, Mutoh T, Adachi T, Suzuki H, Saruta K, Iwasato T, Itohara S, Hashimoto M, Nakajima K, Ogawa M, Kulkarni AB, Mikoshiba K. :
Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.
Development.2007;134(12):2273-82.
38Okada M, Kawahara G, Noguchi S, Sugie K, Murayama K, Nonaka I, Hayashi YK, Nishino I.
Primary collagen VI deficiency is the second most common congenital muscular dystrophy in Japan.
Neurology 2007;69:1035-1042
39SekiT, Namba T, Mochizuki H, Onodera M,
Clustering, migration and neurite formation of neural precusor cells in the adult rat hippocampus .
J Comp Neurol, 10; 502: 275-290, 2007
40Saiki M, Saiki S, Sakai K, Matsunari I, Higashi K, Murata KY, Hattori N, Hirose G.
Neurological deficits are associated with increased brain calcinosis, hypoperfusion, and hypometabolism in idiopathic basal ganglia calcification.
Mov Disord. 2007 May 15;22(7):1027-30.
41Satake W, Mizuta I, Suzuki S, Nakabayashi Y, Ito C, Watanabe M, Takeda A, Hasegawa K, Sakoda S, Yamamoto M, Hattori N, Murata M, Toda T.
Fibroblast growth factor 20 gene and Parkinson's disease in the Japanese population.
NeuroReport 18:937-40, 2007
42Setsuie R, Wang YL, Mochizuki H, Osaka H, Hayakawa H, Ichihara N, Li H, Furuta A, Sano Y, Sun YJ, Kwon J, Kabuta T, Yoshimi K, Aoki S, Mizuno Y, Noda M, Wada K.
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.
Neurochem Int. 2007;50(1):119-29.
43Shibazaki K, Iguchi Y, Kimura K, Wada K, Ueno Y, Sunada Y.
Paradoxical brain embolism associated with HCV-related type II mixed cryoglobulinemia.
J Clin Neurosci 2007;14:780-782
44Shibazaki K, Iguchi Y, Inoue T, Ueno Y, Kimura K.
Serial contrast saline transcranial Doppler examination in a patient with paradoxical brain embolism associated with pulmonary embolism.
J Clin Neurosci 2007;14:788-791
45Suzuki K, Okuma Y, Hattori N, Kamei S, Yoshii F, Utsumi H, Iwasaki Y, Iijima M, Miyamoto T, Miyamoto M, Hirata K.
Characteristics of sleep disturbances in Japanese patients with Parkinson’s disease. A study using Parkinson’s Disease Sleep Scale.
Mov Disord 22:1245-1251,2007
46Tani M, Natori S, Noda K, Fujishima K, Hattori N, Mizuno Y, Okuma Y.
Isolated reversible splenial lesion in adult meningitis: a case report and review of the literature.
Intern Med. 2007;46(18):1597-600.
47Tamura Y, Ogihara T, Uchida T, Ikeda F, Kumashiro N, Nomiyama T, Sato F, Hirose T, Tanaka Y, Mochizuki H, Kawamori R, Watada H
A melioration of glucose tolerance by hepatic inhibition of nuclear factor κB in db/db mice.
Diabetologia 50(1):131-41, 2007
48Tomiyama H, Funayama M, Mizuno Y, Hattori N.
LRRK2 in neurodegenerative disorders (Review).
CNS drugs 2007;21 Spec. issue 1:63-71.
49Ueno Y, Kimura K, Iguchi Y, Shibazaki K, Inoue T, Hattori N, Urabe T.
Mobile aortic plaques are a cause of multiple brain infarcts seen on diffusion-weighted imaging.
Stroke 2007;38:2470-2476
50Ueno Y, Iguchi Y, Shibazaki K, Inoue T, Hattori N, Urabe, T, Kimura K.
Paradoxical brain embolism may not be uncommon-Prospective study in acute ischemic stroke.
J Neurol 2007;254:763-766
51Ueno Y, Kimura K, Iguchi Y, Shibazaki K, Inoue T, Urabe T.
Right-to-left shunt and lacunar stroke in patients without hypertension and diabetes.
Neurology 2007;68:528-531
52Ura S, Hayashi YK, Goto K, Astejada MN, Murakami T, Nagato M, Ohta S, Daimon Y, Takekawa H, Hirata K, Nonaka I, Noguchi S, Nishino I.
Limb-girdle muscular dystrophy due to emerin gene mutations.
Archives of neurology 2007;64:1038-1041
53Yamashiro K, Liu R, Maeda M, Hattori N, Urabe T.
Induction and selective accumulation of mutant ubiquitin in CA1 pyramidal neurons after transient global ischemia.
Neuroscience 2007;147:71-9
54Yasuda T, Fukuda-Tani M, Nihira T, Wada K, Hattori N, Mizuno Y, Mochizuki H.
Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson’s disease.
Exp Neurol 2007;206:308-317
55Yasuda T, Miyachi S, Kitagawa R, Wada K, Nihira T, Ren YR, Hirai Y, Ageyama N, Terao K, Shimada T, Takada M, Mizuno Y, Mochizuki H.
Neuronal specificity of alpha-synuclein toxicity and effect of Parkin co-expression in primates.
Neuroscience 2007;144:743-753
56Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC.
Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.
J Neurochem 100(2):368-381.2007
57Matsuda H,Mizumura S,Nagao T,Ota T,Iizuka T,Nemoto K,Takamura N,Arai H,Homma A.
Automated Discrimination Between Very Early Alzheimer disease and Controls Using an Easy Z-Score Imaging system for Multicenter Brain Perfusion Single-Photon Emission Tomography.
AJNR Am J Neuroradiol. 28:731-736.2007
58Murayama N,Iseki E,Yamamoto R,Kimura M,Eto K,Arai H.
Utility of the Bender Gestalt Test for Diffrentiation of Dementia with Lewy Bodies from Alzheimer's Disease in Patients Showing Mild to Moderate Dementia.
DementGeriatr Cogn Disord.23:258-263.2007
59Yamamoto R,Iseki E,Murayama N,Minegishi M,Marui W,Togo T,Katsuse O,kosaka K,Kato M,Iwatsubo T,Arai H.
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60Kitazawa S, Moizumi S, Okuzumi A, Saito F, Shibuya S, Takahashi T, Wada M, and Yamamoto S.
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61Lu X, Miyachi S, Ito Y, Nambu A, Takada A.
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Eur J Neurosci. Apr;25(8):2374-82, 2007
62Moizumi, S., Yamamoto, S. & Kitazawa, S.
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Neurosci Res. Sep;59(1):60-7, 2007
63Ono, F., & Kawahara, J.
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64Ono, F., Yamada, K., Chujo, K., & Kawahara, J.
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Percept Psychophys. May;69(4):544-9, 2007
65Suzuki A, Ivandini TA, Yoshimi K, Fujishima A, Oyama G, Nakazato T, Hattori N, Kitazawa S, Einaga Y.
Fabrication, characterization, and application of boron-doped diamond microelectrodes for in vivo dopamine detection.
Anal Chem. 2007 Nov 15;79(22):8608-15. Epub 2007 Oct 6.
66Shibuya S, Takahashi T, Kitazawa S.
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Exp Brain Res. 179:709-721, 2007
67Uchida Y, Lu X, Ohmae S, Takahashi T & Kitazawa S.
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68Yamamoto K., Kawato M, Kotosaka S, Kitazawa S.
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69Iwai K, Koike M, Ohshima S, Miyatake K, Uchiyama Y, Saeki Y, Ishii M (2007)
RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway.
J Bone Miner Res 22:1612-1620
70Somboonthum F, Yoshii H, Okamoto S, Koie M, Gomi Y, Uchiyama Y, Takahashi M, Yamanishi K, Mori Y (2007)
Generation of a recombinant Oka varicella vaccine expressing mumps virus hemagglutinin-neuraminidase protein as a polyvalent live vaccine.
Vaccine 25:8741-8755
71Hida T, Ikeda H, Kametaka S, Akazawa C, Kohsaka S, Ebisu S, Uchiyama Y, Waguri S (2007)
Specific depletion of GGA2 causes cathepsin D missorting in HeLa cells.
Arch Histol Cytol 70:303-312
72Tulone C, Uchiyama Y, Novelli Y, Grosvenor N, Saftig P, Chain BM (2007)
Haematopoietic development and immunological function in the absence of cathepsin D.
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73Miyanishi M, Tada K, Koike M, Uchiyama, Y, Kitamura T, Nagata S (2007)
Identification of Tim-4 as a phosphatidylserine receptor.
Nature 450: 435-439
74Komatsu M, Waguri S, Koike M, Sou1 Y, Ueno T, Hara H, Mizushima N, Iwata J, Ezaki J, MurataS, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka T (2007)
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
Cell 131: 1149-1163
75Yamasaki R, Zhang J, Koshiishi I, Suniarti DFS, Wu Z, Peters C, Schwake M, Uchiyama Y, Kira J, Saftig P, Utsumi H, Nakanishi H (2007)
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76Yamanaka I, Koinuma S, Shigeyoshi Y, Uchiyama Y, Yagita K (2007)
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77Nakahara, M., Nagasaka, A., Koike, M., Uchida, K., Kawane, K., Uchiyama, Y., Nagata, S. (2007)
Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens.
FEBS J 274: 3055-3064
78Komatsu, M, Ueno, T, Waguri, S, Uchiyama, Y, Kominami, E, Tanaka, K (2007)
Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.
Cell Death Diff 14:887-894
79Shacka JJ, Klocke BJ, Young C, Shibata M, Olney JW, Uchiyama Y, Saftig P, Roth KA (2007)
Cathepsin D Deficiency Induces Persistent Neurodegeneration in the Absence of Bax-Dependent Apoptosis.
J Neurosci, 27: 2081-2090
80Yagi R, Waguri S, Sumikawa S, Nada S, Oneyama C, Itami S, Schmedt C, Uchiyama Y, Okada M (2007)
C-terminal Src kinase controls development and maintenance of mouse squamous epithelia.
EMBO J 26: 1234-1244
81Shacka JJ, Lu J, Xie ZL, Uchiyama Y, Roth KA, Zhang J. (2007)
Kainic acid induces early and transient autophagic stress in mouse hippocampus.
Neurosci Lett. 414: 57-60

英文原著(2006年)

1Akagawa M, Ito S, Toyoda K, Ishii Y, Tatsuda E, Shibata T, Kawai Y, Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K:
Bispecific antibodies against modified protein and DNA with oxidized lipids.
Proc Natl Acad Sci 2006;103:6160-6165
2Arai T, Fukae J, Hatano T, Kubo S, Ohtsubo T, Nakabeppu Y, Mori H, Mizuno Y, Hattori N.
Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson’s disease.
Acta Neuropathol 2006;112: 139-145
3Arai H, Furuya T, Mizuno Y, Mochizuki H.
Inflammation and infection in Parkinson’s disease. 
Histol Histopathol21: 2006;673-678
4Cao XQ, Arai H, Ren YR, Ooizumi H, Zhang N, Seike S, Furuya T, Yasuda T, Mizuno Y, Mochizuki H,
Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels,
J Neurochemistry 2006;99: 861-867
5Goto K, Nishino I, Hayashi YK.
Rapid and accurate diagnosis of facioscapulohumeral muscular dystrophy.
Neuromuscul Disord 2006;16:256-261
6Hattori N, Machida Y, Sato S, Noda K, Iijima-Kitami M, Kubo S, Mizuno Y.
Molecular mechanisms of nigral neurodegeneration in Park2 and regulation of parkin protein by other proteins.
J Neural Transm Suppl. 70, 2006, pp205-208
7Hayashi A, Nagaoka M, Mizuno Y:
Music therapy in Parkinson’sdisease: Improvement of parkinsonian gait and depression with rhythmic auditory stimulation.
Parkinsonism & Related disorders 2006;12,s76
8Hayashita-Kinoh H, Yamada M, Yokota T, Mizuno Y, Mochizuki H.
Down-regulation of α-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson’s disease rat model.
Biochemical and Biophysical Research Communications 2006;341(4): 1088-1095
9Hino-Fukuyo N, Haginoya K, Hayashi YK, Nishino I, Murakami T, Nonaka I, Togashi K, Tanaka S, Takayanagi M, Yokoyama H, Sakamoto O, Abe T, Toda T, Iinuma K.
A case of Fukuyama-type congenital muscular dystrophy with a very mild mental deficit.
Neuromuscul Disord 2006;16:274-276
10Ishihara L, Gibson RA, Warren L, Amouri R, Lyons K, Wielinski C, Hunter C, Swartz JE, Elango R, Akkari A, Leppert D, Surh L, Reeves KH, Thomas S, Ragone L, Hattori N, Pahwa R, Jankovic J, Nance M, Freeman A, Gouider-Khouja N, Kefi M, Bouar M, Sassi SB, Yahmed SB, Euch-Fayeche EG, Middleton L, Burn DJ, Watts RL, l Hentati F:
Clinical features of Parkinson Disease patients with and without LRRK2 G2019S mutations .
Arch Neurol 2006;63:1250-1254
11Ibarra M CA, Wu S, Murayama K, Minami N, Ichihara Y, Kikuchi H, Noguchi S, Hayashi YK, Ochiai R, Nishino I.
Malignant hyperthermia in Japan: mutation screening of the entire ryanodine receptor type 1 gene coding region by direct sequencing.
Anesthesiology 2006;104:1146-1154
12Iguchi Yasuyuki, Kimura Kazumi, Kobayashi Kazuto, Ueno Yuji, Inoue Takeshi:
Ischemic stroke with malignancy may be frequently caused by paradoxical embolism.
J Neurol Neurosurg Psychiatry 2006; 77: 1336-1339
13Iguchi Yasuyuki, Kimura Kazumi, Shibazaki Kensaku, Iwanaga Takeshi, Ueno Yuji, Inoue Takeshi.
Transcranial Doppler and carotid duplex ultrasonography findings in bow hunter’s syndrome.
J Neuroimaging 2006;16:278-80
14Iguchi Yasuyuki, Kimura Kazumi, Ueno Yuji, Inoue Tsuyoshi, Wada Kuniyasu, Sunada Yoshihide.
Dysarthria-clumsy hand syndrome originating in the corona radiata: A case report,
Eur J Neruol 2006;13: e6
15Iguchi Yasuyuki, Kimura Kazumi, Inoue Tsuyoshi, Wada Kuniyasu, Ueno Yuji, Sunada Yoshihide.
Diffusion-weighted MR images in patient with neuropsychiatric lupus: A case report.
J Clin Neurosci 14: 2006: 273-275
16Iguchi Yasuyuki, Wada Kuniyasu, Shibazaki Kensaku, Inoue Takeshi, Ueno Yuji, Yamashita Shinji, Kimura Kazumi.
First impression at stroke onset plays an important role in early hospital arrival.
Intern Med 2006;45: 447-51
17Kawabata K, Migita M, Mochizuki H, Miyake K, Igarashi T, Fukunaga Y, Shimada T,
Ex vivo cell-mediated gene therapy for metachromatic leukodystrophy using neurospheres,
Brain Res, 2006;1094, 13-23
18Kimura K, Nagao Y, Hachimori K, Shimohira M, Nomura Y, Segawa M.
Myoclonus Associated with Generalized Epilepsy in Childhood-Neurophysiological Evaluation.
Proceedings of 10th International Child Neurology Congress, Montreal (Canada), June 11-16, 2006. Medimond, Bologna (Italy), 2006, pp.277-279
19Kitami MI, Kitami T, Nagahama M, Tagaya M, Hori S, Kakizuka A, Miauno Y, Hattori N.
Dominant-negative effect of mutant valosin-containing protein in aggresome formation.
FEBS Lett 2006;580: 474-478
20Komine-Kobayashi M, Zhang N, Liu M, Tanaka R, Hara H, Osaka A, Mochizuki H, Mizuno Y, UrabeT.
Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice.
J Cereb Blood Flow Metab (2005 July, EPUB), 2006;26: 402-413
21Kubo S, Hattori N, Mizuno Y.
Recessive Parkinson’s Disease.
Mov Disord 2006;21(7): 885-893
22Liewluck T, Pho-Iam T, Limwongse C, Thongnoppakhun W, Boonyapisit K, Raksadawan N, Murayama K, Hayashi YK, Nishino I. Sangruchi T.
Mutation analysis of the GNE gene in distal myopathy with rimmed vacuoles (DMRV) patients in Thailand.
Muscle Nerve 34: 775–778, 2006
23Liu R, Suzuki A, Guo Z, Mizuno Y, Urabe T.
Intrinsic and extrinsic erythropoietin enhances neuroprotection against ischemia and reperfusion injury in vitro.
J Neurochem 2006;96(4): 1101-1110
24Maraganore DM, de Andrade M, Elbaz A, Farrer MJ, Ioannidis JP, Kruger R, Rocca WA, Schneider NK, Lesnick TG, Lincoln SJ, Hulihan MM, Aasly JO, Ashizawa T, Chartier-Harlin MC, Checkoway H, Ferrarese C, Hadjigeorgiou G, Hattori N, Kawakami H, Lambert JC, Lynch T, Mellick GD, Papapetropoulos S, Parsian A, Quattrone A, Riess O, Tan EK, Van Broeckhoven C: Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium.
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
JAMA 2006;296:661-670
25Matsuda N, Kitami T, Suzuki T, Mizuno Y, Hattori N, Tanaka K:
Diverse effects of pathogenic mutations of Parkin that catalyzes multiple monoubiquitylation in vitro.
J Biol Chem 2006;281:3204-3209
26Miyamoto, N, Kagohashi, M, Nishioka, K, Fujishima, K, Kitada, T, Tomita, Y, Mori, K, Maeda, M, Wada, R, Matsumoto, M, Mori, H, Mizuno, Y, Okuma, Y. 
An Autopsy Case of Schilder's Variant of Multiple Sclerosis (Schilder's Disease)
Eur Neurol 2006;55:103-107
27Mizuno Y, Hattori N, Yoshino H, Hatano Y, Satoh K, Tomiyama H, Li Y.
Progress in familial Parkinson's disease (Review).
J Neural Transm Suppl. 2006;(70):191-204.
28Murakami T, Hayashi YK, Noguchi S, Ogawa M, Nonaka I, Tanabe Y, Ogino M, Takada F, Eriguchi M, Kotooka N, Campbell KP, Osawa M, Nishino I.
Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness.
Ann Neurol 2006;60:597-602
29Nakamura A, Kitami T, Mori H, Mizuno Y, Hattori N.
Nuclear localization of the 20S proteasome subunit in Parkinson's disease.
Neurosci Lett. 2006;406(1-2):43-8
30Naito S, Mochizuki H, Yasuda T, Mizuno Y, Furusaka M, Ikeda S, Adachi T, Shimizu H, Suzuki J, Fujiwara S, Okada T, Nishikawa K, Aoki S, Wada K
Characterization of multimetric variants of ubiquitin carboxyl-terminal Hydrolase L1 in water by small-angle neutron scattering.
Biochem Biophys Res Commun 2006;339 (2); 717-725
31Nishioka K, Fujishima K, Kobayashi H, Mizuno Y, Okuma Y.
An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome.
Clin Neurol Neurosurg 2006;108:772-774
32Nishioka K, Hayashi S, Farrer MJ, Singleton AB, Yoshino H, Imai H, Kitami T, Sato K, Kuroda R, Tomiyama H, Mozoguchi K, Murata M, Toda T, Imoto I, Inazawa J, Mizuno Y, Hattori N.
Clinical Heterogeneity of α-Synuclein Gene Duplication in Parkinson’s Disease.
Ann Neurol 2006;59(2): 298-309
33Ohta E, Funayama M, Ichinose H, Urano F, Toyoshima I, Matsuo M, Nishida T, Yukihiko K, Yoshino S, Yokoyama H, Shimazu H, Maeda K, Hasegawa K, Obata F.
Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia.
Arch Nrurol. 2006;63: 1605-1610
34Ozawa R, Hayashi YK, Ogawa M, Kurokawa R, Matsumoto H, Noguchi S, Nonaka I, Nishino I.
Emerin-lacking mice show minimal motor and cardiac dysfunctions with nuclear-associated vacuoles.
Am J Pathol 2006;168:907-917
35Ren YR, Nishida Y, Yoshimi K, Yasuda T, Jishage K, Uchihara T, Yokota T, Mizuno Y, Mochizuki H.
Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain.
J Neurochem. 2006;98(6):1810-6
36Ren Y-R, Yoshimi K, Yasuda T, Nishida Y, Yokota T, Uchihara T, Jishage K, Mizuno Y, Mochizuki H,
Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain,
J Neurochem, 2006;98, 1808-1813
37Ruiqin Liu, Asuka Suzuki, Zhiwei Guo, Yoshikuni Mizuno, Takao Urabe.
Intrinsic and extrinsic erythropoietin enhances neuroprotection against ischemia and reperfusion injury in vitro.
J Neurochem. 2006;96, 1101-1110
38Ruiqin Liu, Masao Moroi, Masato Yamamoto, Tetsuya Kubota, Tsuyoshi Ono, Atsushi Funatsu, Hiroki Komatsu, Takahiro Tsuji, Hisao Hara, Hidehiko Hara, Taro Tsunoda, Masato Nakamura, Hironori Hirai, Tetsu Yamaguchi.
Presence and Severity of Chlamydia pneumoniae and Cytomegalovirus Infection in Coronary Plaques Are Associated With Acute Coronary Syndromes.
Int Heart J. 2006;47(4):511-519
39Sher I, Zisman-Rozen S, Eliahu L, Whitelock JM, Maas-Szabowski N, Yamada Y, Breitkreutz D, Fusenig NE, Arikawa-Hirasawa E, Iozzo RV, Bergman R, Ron D.
Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermis formation.
J Biol Chem 281(8): 5178-5187, 2006
40Sato S, Chiba T, Nishiyama S, Kakiuchi T, Tsukada H, Hatano T, Fukuda T, Yasoshima Y, Kai N, Kobayashi K, Mizuno Y, Tanaka K, Hattori N:
Decline of striatal dopamine release in parkin-deficient mice shown by ex vivo autoradiography.
J Neurosci Res 2006;84:1350-1357
41Sato S, Chiba T, Sakata E, Kato K, Mizuno Y, Hattori N, Tanaka K:
14-3-3ɳ is a novel regulator of parkin ubiquitin-ligase.
EMBO J 2006;25:211-221
42Sato K, Hatano T, Yamashiro K, Kagohashi M, Nishioka K, Izawa N, Machizuki H, Hattori N, Mori H, Mizuno Y,
The Juntedo Parkinson Study Group. Prognosis of Parkinson’s Disease: Time to Stage III, IV, V, and to Motor Fluctuations.
Mov Disords 2006;21(9): 1384-1395
43Tomiyama H, Li Y, Funayama M, Hasegawa K, Yoshino H, Kubo S, Sato K, Hattori T, Lu CS, Inzelberg R, Djaldetti R, Melamed E, Amouri R, Gouider-Khouja N, Hentati F, Hatano Y, Wang M, Imamichi Y, Mizoguchi K, Miyajima H, Obata F, Toda T, Farrer MJ, Mizuno Y, Hattori N.
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries.
Movement disorders, 2006 Aug;21(8):1102-8
44Ueno Y, Fujishima K, Kobayashi H, Mizuno Y, Okuma Y.
Cortical myoclonus due to hypocalcemia 12 years after thyroidectomy.
Clin Neurol Neurosurg 2006;108:400-403
45Ueno Y, Kimura K, Iguchi Y, Inoue T, Wada K, Urabe T, Sunada Y:
Acute confusional state caused by a large number of small brain infarcts.
European J Neurol 2006;13: e2-e3.
46Wada K, Arai H, Takanashi M, Fukae J, Oizumi H, Yasuda T, Mizuno Y, Mochizuki H,
Expression levels of VEGF and its receptors in Parkinson's disease,
NeuroRepot, 2006;15, 705-709
47Wada M, Yoshimi K, Higo N, Ren YR, Mochizuki H, Mizuno Y, Kitazawa S,
Statistical parametric mapping for cell density of microglias and dopamine neurons,
Neruosi Res, 2006;56, 96-102
48Waragai M, Chiba A, Uchibori A, Fukushima T, Anno M, Tanaka K,
Anti-Ma2 associated paraneoplansic neurological syndrome presenting as enchphalitis and progressive muscular atrophy.
J Neurol Neurosurg Psychiatry 2006;77:111-113
49Watanabe T, Zhang N, Liu M, Tanaka R, Mizuno Y, Urabe T.
Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion.
Stroke 2006;37: 1539-1545
50Wu S, Ibarra MC, Malicdan MC, Murayama K, Ichihara Y, Kikuchi H, Nonaka, I, Noguchi S, Hayashi YK Nishino, I.
Central core disease is due to RYR1 mutations in more than 90% of patients.
Brain 2006;129:1470-1480
51Yamamoto S, Fukae J, Mori H, Mizuno Y, Hattori N:
Positive immunoreactivity for vesicular monoamine transporter 2 in Lewy bodies and Lewy neurites in substantia nigra.
Neurosci Lett 2006;396:187-191
52Yamashiro K, Watanabe T, Tanaka R, Komine-Kobayashi M, Mizuno Y, Urabe T.
Clustering of risk factors increases the incidence of echolucent carotid plaque in stroke patients.
Cerebrovasc Dis 2006;22: 432-438
53Yoritaka A, Hishima T, Akagi K, Kishida S.
Successful steroid treatment of acquired idiopathic partial hypohydrosis.
J Dermatology. 2006;33:265-267
54Arai H, Takano M, Miyakawa K, Ota T, Takahashi T, Asaka H, Kawaguchi T.
A quantitative near-infraredspectroscopy study: A decrease in cerebral hemoglobin oxygenation in Alzheimer's disease and mild cognitive impairment.
Brain Cogn.61:189-194.2006
55Liu J, Suzuki T, Seki T, Namba T, Tanimura A, Arai H.
Effects of repeated phencyclidine administration on adult hippocampal neurogenesis in the rat.
Synapse.60:56-68.2006
56Nakamura K,Koyama Y,Takahashi K,Tsurui H,Yan X ,Ohtsuji M,Qing S-L,Sugawara Y,Sawabe K,Ohashi A,Ohnuma T,Arai H,Nishimura H,Hasegawa H,and Hirose S.
Requirement of Trypotophan Hydroxylase During Development for Maturation of Sensorimotor Gating.
J.Mol.Biol.363:345-354.2006
57Oshima K,Akiyama H,Tsuchiya K,Kondo H,Haga C,Shimomura Y,Iseki E,Uchikado H,Kato M,Niizato K,Arai H.
Relative paucity of tau accumulation in the small areas with abundant Aβ42-positive capillary amyloid angiopathy within a given cortical region in the brain of patients with Alzheimer pathology.
ActaNeuropathol.111:510-518.2006
58Shibata N, Ohnuma T, Higashi S, Higashi M, Usui C, Ohkubo T, Watanabe T, Kitajima A, Ueki A, Nagao M, Arai H.
Genetic association between USF1 and USF2 Gene polymorphisms and Japanese Alzheimer's Disease.
Journal ofGerontology.61:660-662.2006
59Shibata N, Ohnuma T, Higashi S, Higashi M, Usui C, Ohkubo T, Watanabe T, Kitajima A, Ueki A, Nagao M, Arai H.
Genetic association between Notch4 polymorphisms and Japanese schizophrenics.
Psychiatr Genet.16:77-79.2006
60Usui C, Shibata N, Ohnuma T, Higashi S, Ohkubo T, Ueki A, Nagao M, Arai H.
No Genetic Association between the Myeloperoxidase Gene -463 Polymorphism and Estrogen Receptor-alpha Gene Polymorphisms and Japanese Sporadic Alzheimer's Disease.
Dement Geriatr Cogn Disord. 21:296-299.2006
61Ashe J, Lungu OV, Basford AT, Lu X.
Cortical control of motor sequences.
Curr Opin Neurobiol 2006;Apr;16(2):213-21.
62Kitazawa, S, Wolpert, DM.
Response to Gilbert: Rhythmicity, randomness and synchrony in climbing fiber signals.
Trends Neurosci. 2006 Feb;29(2):66-7.
63Miyachi S, Lu X, Imanishi M, Sawada K, Nambu A, Takada M.
Somatotopically arranged inputs from putamen and subthalamic nucleus to primary motor cortex.
Neurosci Res. 2006; 56(3):300-8.
64Miyazaki, M., Yamamoto, S., Uchida, S. & Kitazawa, S.
Bayesian calibration of simultaneity in tactile temporal order judgment.
Nat Neurosci. 2006: 9(7):875-7.
65Uka T, DeAngelis GC.
Linking neural representation to function in stereoscopic depth perception: roles of the middle temporal area in coarse vs. fine disparitydiscrimination.
J Neurosci. 2006: 26: 6791-6802.
66Wada M, Yoshimi K, Higo N, Ren YR, Mochizuki H, Mizuno Y, Kitazawa S.
Statistical parametric mapping of immunopositive cell density.
Neurosci Res, 2006: 56 (1) 96-102.
67Zhu, J-H, Horbinski, C., Guo, F., Watkins, S., Uchiyama, Y., Chu, C.T. (2006)
Reguration of autophagy by extracellular signal regulated protein kinases during 1-methyl-4-phenylpyridinium injury.
Am J Pathol 170:75-86
68Waguri, S., Tomiyama, Y., Hida, T., Sakai, N., Taniike, M., Wakasugi, M., Ebisu, S., Uchiyama, Y. (2006)
The luminal domain participates in the endosomal trafficking of the cation-independent mannose 6-phosphate receptor.
Exp. Cell Res. 312: 4090-4107
69Yamada S, Isojima Y, Kanamori S, Waguri S, Uchiyama Y, Nagai K. (2006)
Uncoupling protein 2 negatively regulates neurite extensions in PC12h cells.
Neurosci Lett. 410(2):110-114
70Yae K, Keng VW, Koike M, Yusa K, Kouno M, Uno Y, Kondoh G, Gotow T, Uchiyama Y, Horie K, Takeda J. (2006)
Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth.
Mol Cell Biol. 26: 6185-6196
71Ishii M, Iwai K, Koike M, Ohshima S, Kudo-Tanaka E, Ishii T, Mima T, Katada Y, Miyatake K, Uchiyama Y, Saeki Y. (2006)
RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis.
J Bone Miner Res. 21: 965-976
72Yoshimura K, Shibata , Koike M, Gotoh K, Fukaya M, Watanabe M, Uchiyama Y (2006)
Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues.
Autophagy 2: 200-208
73Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Ueno Koike M, Uchiyama Y, Kominami E, Tanaka K (2006)
Loss of autophagy in the central nervous system causes neurodegeneration.
Nature 441: 880-884
74Shimamura M, Sato N, Waguri S, Uchiyama Y, Hayashi T, Iida H, Nakamura T, Ogihara T, Kaneda Y, Morishita R (2006)
Gene transfer of HGF gene improves learning and memory in the chronic stage of cerebral infarction.
Hypertension 47: 742-751
75Zhu C, Xu F, Wang X, Shibata M, Uchiyama Y, Blomgren K, Hagberg H (2006)
Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia.
J Neurochem, 96: 1016–1027
76Shacka J, Klocke BJ, Shibata M, Uchiyama Y, Datta G, Schmidt RE, Roth KA (2006)
Bafilomycin A1 Inhibits Chloroquine-Induced Death of Cerebellar Granule Neurons.
Mol Pharacol 69: 1125-1136
77Sasaki T, Gotow T, Shiozaki M, Sakaue F, Saito T, Julien JP, Uchiyama Y, Hisanaga S. (2006)
Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants.
Hum Mol Genet. 15:943-952

英文原著(2005年)

1Clarimon J, Johnson J, Djaldetti R, Hernandez D, Hattori N, Sroka H, Barhom Y, Singleton A.
Mutation of the Parkin gene in a Persian family: Clinical progression over a 40-year period.
Mov Disord Apr 25; 887-890, 2005
2Fukae J, Kubo SI, Hattori N, Komatsu K, Kato M, Aoki M, Mizuno Y.
Hoarseness due to bilateral vocal cord paralysis as an initial manifestation of familial amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis 6: 122-124, 2005
3Fukae J, Takanashi M, Kubo S, Nishioka K, Nakabeppu Y, Mori H, Mizuno Y, Hattori N.
Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson’s disease and related neurodegenerative disorders.
Acta Neuropathol 109: 256-262, 2005
4Funayama M, Hasegawa K, Ohta E, Kawashima N, Komiyama M, Kowa H, Tsuji S, Obata F.
An LRRK2 Mutation as a Cause for the Parkinsonism in the Original PARK8 Family.
Ann Neurol 57(6): 918-921, 2005
5Gou L, Itaya M, Takanashi M, Mizuno Y, Mori H.
Relationship between Parkinson disease with dementia and dementia with lewy body.
Parkinsonism Rel Disord 11: 305-309, 2005
6Hisanaga K, Iwasaki Y, Itoyama Y, Neuro-Sweet Disease Study Group (Okuma Y is one of the members of the study group).
Neuro-Sweet disease: clinical manifestations and criteria for diagnosis.
Neurology 64: 1756-1761, 2005
7Ichikawa N, Kasai S, Suzuki N, Nishi N, Oishi S, Fujii N, Kadoya Y, Hatori,K Mizuno Y, Nomizu M, Arikawa-Hirasawa E.
Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain.
Biochemistry 44(15): 5755-5762, 2005
8Ide M, Yamada K, Toyota T, Iwayama Y, Ishitsuka Y, Minabe Y, Nakamura K, Hattori N, Asada T, Mizuno Y, Mori N, Yoshikawa T.
Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson's disease.
Hum Genet 117: 520-527, 2005
9Inzelberg R, Hattori N, Mizuno Y.
Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation.
Neurology 65:1843, 2005
10Kagamihara Y, Masakado Y.
Excitability of spinal inhibitory circuits in patients with spasticity.
J Clin Neurophysiol Apr 22(2): 136-147, 2005
11Kosik KS, Shimura H.
Phosphorylated tau and the neurodegenerative foldopathies.
Biochem Biophys Acta 1739(2-3): 298-310, 2005
12Li Y, Tomiyama H, Sato K, Hatano Y, Yoshino H, Atsumi M, Kitaguchi M, Sasaki S, Kawaguchi S, Miyajima H, Toda T, Mizuno Y, Hattori N.
Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism.
Neurology 64: 1955-1957, 2005
13Li X, Kitami T, Wang M, Mizuno Y, Hattori N.
Geographic and ethnic differences in frequencies of two polymorphisms (D/N394 and L/I272) of the parkin gene in sporadic Parkinson’s disease.
Parkinsonism Rel Disord 11: 485-491, 2005 
14Liu R, Yamamoto M, Moroi M, Kubota T, Ono T, Funatsu A, Komatsu H, Tsuji T, Hara H, Hara H, Nakamura M, Hirai H, Yamaguchi T.
Chlamydia pneumoniae immunoreactivity in coronary artery plaques of patients with acute coronary syndromes and its relation with serology.
Am Heart J 150(4): 681-688, 2005
15Lu CS, Simons EJ, Wu-Chou YH, Fonzo AD, Chang HC, Chen RS, Weng YH, Rohe CF, Breedveld GJ, Hattori N, Gasser T, Oostra BA, Bonifati V.
The LRRK2 I2012T, G2019S, and I2020T mutations are rare in Taiwanese patients with sporadic Parkinson's disease.
Parkinsonism Relat Disord 11: 521-522, 2005
16Masakado Y, Kagamihara Y, Takahashi O, Akaboshi K, Muraoka Y, Ushiba J.
Post-activation depression of the soleus H-reflex in stroke patients.
Electromyogr Clin Neurophysiol 45(2): 115-122, 2005
17Matsuda C, Kameyama K, Tagawa K, Ogawa M, Suzuki A, Yamaji S, et al.
Dysferlin interacts with affixin (beta-parvin) at the sarcolemma.
J Neuropathol Exp Neurol 64: 334-340, 2005
18Matsumoto H, Hayashi YK, Kim DS, Ogawa M, Murakami T, Noguchi S, et al.
Congenital muscular dystrophy with glycosylation defects of alpha-dystroglycan in Japan.
Neuromuscul Disord 15: 342-348, 2005
19Mitsuhashi H, Yoshikawa A, Sasagawa N, Hayashi YK, Ishiura S.
Denervation enhances the expression of SHPS-1 in rat skeletal muscle.
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